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<entry dataset="Swiss-Prot" created="2009-01-20" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQP5</accession>
    <name>AHPD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase AhpD</fullName>
            <ecNumber evidence="2">1.11.1.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Alkylhydroperoxidase AhpD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ahpD</name>
        <name type="ordered locus">AZC_1050</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="Rhea" id="RHEA-COMP:16355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.11.1.28"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AhpD family.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.28" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169581.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HQP5"/>
    <dbReference type="SMR" id="A8HQP5"/>
    <dbReference type="STRING" id="438753.AZC_1050"/>
    <dbReference type="EnsemblBacteria" id="BAF87048">
        <property type="protein sequence ID" value="BAF87048"/>
        <property type="gene ID" value="AZC_1050"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1050"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105328_0_0_5"/>
    <dbReference type="OMA" id="AIMAMNN"/>
    <dbReference type="OrthoDB" id="1427837at2"/>
    <dbReference type="BRENDA" id="1.11.1.28">
        <property type="organism ID" value="609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008785">
        <property type="term" value="F:alkyl hydroperoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032843">
        <property type="term" value="F:hydroperoxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01676">
        <property type="entry name" value="AhpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004674">
        <property type="entry name" value="AhpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00777">
        <property type="entry name" value="ahpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0049">Antioxidant</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0575">Peroxidase</keyword>
    <keyword id="KW-0676">Redox-active center</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000359471" description="Alkyl hydroperoxide reductase AhpD">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="2">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Interchain (with AhpC); in linked form" evidence="2">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01676"/>
        </source>
    </evidence>
    <sequence length="181" mass="18933" checksum="A6BDED0A664A4CD1" modified="2007-12-04" version="1">MSIEALKTQLPAFAKDVKLNLSALPREDSLTEQQLYGLLVACGYTTRNGTVAQALEAEAAPHLSPAALDAAKAAASIMAMNNVYYRFTHLASNKAYETLPAKLRMSVIGNPGVDKVDFELWSLAVSAMNGCGRCIDAHEAVLREAGLSEAQIQTAVRVGAIIASAAVALEAAGAGFPEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQR6</accession>
    <name>A8HQR6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Phosphonate uptake transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1056</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169587.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1056"/>
    <dbReference type="EnsemblBacteria" id="BAF87054">
        <property type="protein sequence ID" value="BAF87054"/>
        <property type="gene ID" value="AZC_1056"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1056"/>
    <dbReference type="eggNOG" id="COG3639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064254_0_0_5"/>
    <dbReference type="OMA" id="IGQEFLV"/>
    <dbReference type="OrthoDB" id="1209768at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005769">
        <property type="entry name" value="PhnE/PtxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01097">
        <property type="entry name" value="PhnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="96"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="293" mass="31616" checksum="D9C987333F55D350" modified="2007-12-04" version="1">MSATVPSLPPAQAAALAAAYDAATAKARLRSLLVAVVVAALALLAAWFAEVKPGALKDIAHFTDYLAKTIPTISAETPRADIVAWYWDLKNWARLLGETILMAYLGTLFGAIGGFVLCFLASANLVRNKAVIFLTRRFLEFCRTVPDVVFALIFVFAFGLGPVPGVLAISIHTAGALGKLFAEVVENIDMKPVEGLTATGATWVQRVRFGVVPQVLSNFASYGLLRFEINVRGAGVLGFVGAGGIGQEFLTAIRNFYYTDVSAILLMIIATVILIDLGTERIRHRLLFQDQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQY4</accession>
    <name>A8HQY4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">marR</name>
        <name evidence="2" type="ordered locus">AZC_1075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1075"/>
    <dbReference type="EnsemblBacteria" id="BAF87073">
        <property type="protein sequence ID" value="BAF87073"/>
        <property type="gene ID" value="AZC_1075"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1075"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_18_2_5"/>
    <dbReference type="OMA" id="HLTAHAW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="18"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="168" mass="18663" checksum="A1566B43F77AB9D6" modified="2007-12-04" version="1">MLIESMTYKYSAPTLPPATQFGRLVIQVHRLWRRELDHALVGHGLSLATALPLLMLRERGELRQNALAEALGIECPSLVRLLDALAAEGLVERREDPADRRAKVLHLTPLGQRRAQAAEDALVVMRARLLADVSEEDLARTLHVLRTVEGRLDREAETRRPGAEGDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8HR49</accession>
    <name>A8HR49_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative gene transfer agent (GTA) protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1119</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1119"/>
    <dbReference type="EnsemblBacteria" id="BAF87117">
        <property type="protein sequence ID" value="BAF87117"/>
        <property type="gene ID" value="AZC_1119"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1119"/>
    <dbReference type="eggNOG" id="ENOG5032SG3">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164764_0_0_5"/>
    <dbReference type="OMA" id="NKHRGEI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021791">
        <property type="entry name" value="Phage_TAC_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11836">
        <property type="entry name" value="Phage_TAC_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="119" mass="12427" checksum="BB29F428DD58D91A" modified="2007-12-04" version="1">MRRAAMANRHRGEISAHLGGRDRTLVLTLGALAELEAAFAVEDLTALAERFGRGRLCASDMVRLIGAGLRGAGETIDDEEVARLACPEGAVGYARIVSALLSGTFGGGEAPRPPVPQET</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HR85</accession>
    <name>A8HR85_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glucose transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1141</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
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        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR006443">
        <property type="entry name" value="Formate-DH-alph_fdnG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01553">
        <property type="entry name" value="formate-DH-alph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="2">
        <location>
            <begin position="12"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="3">
        <location>
            <begin position="697"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="824" mass="92746" checksum="0AB5C7861A31E357" modified="2007-12-04" version="1">MSSLGPTFGRGAMTNSWTDIRNTDLVVIMGGNAAEAHPCGFKWVVEAKANRGAKLVVVDPRFTRSAAVADYYAPIRQGSDIAFLLGVINYCIQNNKVQWDYVKAFTNATYLVKDGFEYRDGLFTGYDEEKRDYNRSTWDYQIGPDGYAMVDETLENPRCVWNLLKAHVAQYTPEMVERISGTPKDKFLKVAAMIAECSSPTKTMTSMYALGWTQHSKGSQNIRCMAMLQLILGNIGVRGGGMNALRGHSNIQGLTDIGLMSNMIPGYLNLPTEREPDFATYMSTRGFKPLRPNQMSYWQNYKKFMVSFLKSMWGPAATAENNFAFDWLPKLDVPTYDILRAFELMKQGKMNLYFCQGFNPLQAFPNRNKLSAALSRLKMLVIMDPLETETARFWENHGVYNDVDPSKIQTEVIQLPTTCFAEDEGSLVNSGRWLQWHWPAGSPPGEARTDAWIMSQIHLRLKEMYRKEGGALPDPIVNLSWTYKNPDEPTPEELTKELNGYVVSDVLDPNDPTKKLLTAGKQVPNFGVLRDDGSTAAGCWIYSGSFTEDGNMMARRDNSDPDNTGAYLKWSFAWPANRRIIYNRASADINGKPWDDTRKLLWWDGAKWTGYDVPDIAPTAKPQDVGPFIMNPEGVSRLFARGMMRDGPFPVHYEPFESPLVNVIAPKVRGNPVARVFKDDFAQFAEPASKEFPYAATSYRLTEHFHYWTKNNHVNSVLQPEFFVEISEELAKEKSINNGGWVRVWSKRGSVFAKAYVTKRIRPLICDGKPVHVVGIPIHWGFVGAAKKGFPANVLTPFVGDANIETPEFKAFLVNIEPTTGPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRF2</accession>
    <name>A8HRF2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1177</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169708.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1177"/>
    <dbReference type="EnsemblBacteria" id="BAF87175">
        <property type="protein sequence ID" value="BAF87175"/>
        <property type="gene ID" value="AZC_1177"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1177"/>
    <dbReference type="eggNOG" id="COG0247">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005304_1_1_5"/>
    <dbReference type="OMA" id="CPMMIEH"/>
    <dbReference type="OrthoDB" id="1951488at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021872">
        <property type="entry name" value="DUF3483"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11982">
        <property type="entry name" value="DUF3483"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="231"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="304"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="644" mass="67202" checksum="CCCF17A8C0059CC6" modified="2007-12-04" version="1">MAAAFGLSVLVWAMGLSAALALGTRVALWRRGRMARVDWLSGLAAVPKRYLVDVHHVVARDPLAARMHMLAAGGLIAGSGLAALAIVPVLATSSLWWALTALAFATMLAGALLVGGRRYPARPARLSGGRFQILPFLLLGYGLGGFSLASGAVAGLSGGAGFVVLAVTAGCGLALAFLVARGPMRHALAGALHLAAHPRPARFAGRRDVALAPVDLEAETLGVGTPADFGWNRLLGFDACVQCGRCETACPAFAAGQPLNPKRLVQDLVAAMEGSDSAAYSGSPYPNARPVARQGGALSPIVGAGAMIHPDTLWSCTTCRACVEECPMMIEHVDAVIDLRRHRTLMLGAVPEKAAARLDDLRATDEVGGHALAARADFAAGLDLPVLHPEGHADVLLWLGEGAYDLRHGRTLRALVRLLRTAGVDFAILGAAEKDCGDLARRLGDEATFARLARENVATLNALSFGLILTADPHALNSLRNEYPAFGGRYEVWHHTAFLDRLLAEGRLALGAPGHLSVTYHDPCYLGRYNGEVEAPRRLLDALGLRRTEMARHGTRSLCCGGGGGAPHSDIAGDLRIPDLRMDQARATGAAVVAVACPHCAVMLEGVTGARPEVRDVAELVLAAVEAGQAAPASAGARQPEPVA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS18</accession>
    <name>ATPD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-type ATPase subunit delta</fullName>
            <shortName evidence="1">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpH</name>
        <name type="ordered locus">AZC_4128</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="1">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase delta chain family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HS18"/>
    <dbReference type="SMR" id="A8HS18"/>
    <dbReference type="STRING" id="438753.AZC_4128"/>
    <dbReference type="EnsemblBacteria" id="BAF90126">
        <property type="protein sequence ID" value="BAF90126"/>
        <property type="gene ID" value="AZC_4128"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4128"/>
    <dbReference type="eggNOG" id="COG0712">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085114_0_1_5"/>
    <dbReference type="OMA" id="MVDNIQD"/>
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        <location>
            <begin position="1"/>
            <end position="186"/>
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    </evidence>
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        <name evidence="2" type="ordered locus">AZC_4179</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF90177">
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        <property type="gene ID" value="AZC_4179"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Stress-induced_KGG_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10685">
        <property type="entry name" value="KGG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="98" mass="10457" checksum="EA31E392167C2D99" modified="2007-12-04" version="1">MIQEFRTMGDARKGGSKRGFAAMDAEKQRAIARKGGESVPAEKRSFSQNRELASSAGRKGGQSVADEDRSFSRDRSLASQAGQKGGQASHSGNNPQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSP4</accession>
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            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
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            <shortName evidence="2">MetAP</shortName>
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        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
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        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ordered locus">AZC_4203</name>
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    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172723.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4203"/>
    <dbReference type="MEROPS" id="M24.001"/>
    <dbReference type="EnsemblBacteria" id="BAF90201">
        <property type="protein sequence ID" value="BAF90201"/>
        <property type="gene ID" value="AZC_4203"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4203"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_0_0_5"/>
    <dbReference type="OMA" id="RGAESCY"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00680">
        <property type="entry name" value="MAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="27"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="275" mass="29764" checksum="86042C90EFF91595" modified="2007-12-04" version="1">MTYVEAAAAPLRKTGQIKLHGPEGFAAMRKAGQLAAQALDAISEMIGPGVSTEAVDKLVFDFAVSHGAYPATLNYRGYRYSVCTSINHVVCHGMPSPRPLREGDIVNVDVTLVVDGWYGDSSRMYAIGEIPRRAERLIEVTYESMMLGIAAIKPGAHLGDIGAAIQAYVEPQHMSVVRDFCGHGVGQVFHDEPNVVHVGRRGEGPELKPGMIFTVEPMINLGRPHVKVLSDGWTAVTRDRSLSAQFEHAVGVTETGVEIFTLSPKGYHKPPYTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT93</accession>
    <name>A8HT93_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter periplasmic peptide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0812</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0812"/>
    <dbReference type="EnsemblBacteria" id="BAF86810">
        <property type="protein sequence ID" value="BAF86810"/>
        <property type="gene ID" value="AZC_0812"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0812"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_4_5"/>
    <dbReference type="OMA" id="WDTLIYR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723880" evidence="4">
        <location>
            <begin position="46"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="93"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="528" mass="58681" checksum="4718D036B23DF813" modified="2007-12-04" version="1">MPRCWANSTGIQYQTQRENMAFLQSRLSRALAVAMFAIAPAAAHAGKANDTLVYASDSEPENVSPYHNNVREGVIIARHVFDNLIFHDLATGKYEPQLATNWTWADPQTLDLTIRKGVTFHNGDPLTADDVVFTLNYVVSPDSKVVTKQNVNWIKSAEKIGDDKVRIHLVGPFPAAIEYLAGPVVIYPEKYFKKVGLDGFAKAPIGSGPYKVTSVTPGKGVKMEKNTSYWKDSPLGQPKIGKLEFRIIPDPETQVAELMTGGVDWIWRVQADQAKQLGAVPNLTVLSAETMRVGFLQFDSQGRAPGSEPLKDPRVRQAISYAIDRKAMVDNLVRGGARVMNSACFIDQFGCTDKGVPRYDYDPAKAKKLLADAGYPNGFSIDLYAYREREYAEAVVGYLGAVGIKAKLNFMKYAALRELSRSGKVPIYFQTWGSFSVADASAFTGVWFKGDEDDMTRDQQVTDMLKKADTTVETEARLAAYSEALKLIAERAYLLPLFSYSSNYAFTSDLNFNAQPDELPRFFKARWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU19</accession>
    <name>A8HU19_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ordered locus">AZC_0897</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0897"/>
    <dbReference type="EnsemblBacteria" id="BAF86895">
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    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0897"/>
    <dbReference type="eggNOG" id="COG2759">
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    <dbReference type="HOGENOM" id="CLU_003601_3_3_5"/>
    <dbReference type="OMA" id="CGEIMTM"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000270">
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    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0035999">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="578" mass="60969" checksum="FB4E70048D4084EF" modified="2007-12-04" version="1">MTEPSVRFRHRGPRMHTTARHIDPMSDAAIAATVTPEPIEAVGARLGIPADALYRYGPHKAKLSLDFIREIEDRPTGKLILVTAISPTPAGEGKTTTTIGLGDALNRIGAKTAVCLREPSLGPCFGAKGGATGGGRAQIVPMQDINLHFTGDLHAIGAAHNLLSALIDNHIYWGNALDIDTRRIAWKRVVDLNDRALRSIVVGLGGPANGFPREDGFDITVASEVMAIFCLAKSLEELEDRLSQMVVAQTRAKGIVRAEALKGIGSMVALLRDAFQPNLVQTMEHTPAFVHGGPFANIAHGCNSVIATRSALRLADYVVTEAGFGADLGAEKFLDIKCRQAGLAPAASVVVATVRALKMHGGVGLKDLVKEDAGAVVLGAANLRRHVENMQKFGIPVVVALNRFLSDTPAEVDAVRGVLADLGVNVHVCSHWAEGGAGAEALAEEVKMLAARPSQFRTLYPDAMPLAGKIETIAREIYRAGDVALSPDAARRLTELEAAGFGDLPVCMAKTQYSFSADPKLRNAPTGHTIPVREVRLSAGAGFVVALTGDVMTMPGLPSVPAAEHIFVDADGVIGGLS</sequence>
</entry>
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    <accession>A8HU47</accession>
    <name>A8HU47_AZOC5</name>
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            <fullName evidence="1">DUF2007 domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0906</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169437.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0906"/>
    <dbReference type="EnsemblBacteria" id="BAF86904">
        <property type="protein sequence ID" value="BAF86904"/>
        <property type="gene ID" value="AZC_0906"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0906"/>
    <dbReference type="eggNOG" id="ENOG5032YJ8">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_171578_0_1_5"/>
    <dbReference type="OMA" id="LDQNMSI"/>
    <dbReference type="OrthoDB" id="2070137at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2007" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="75" mass="8279" checksum="544D0AD39CB3D6A8" modified="2007-12-04" version="1">MREVVRTNDIVLISAIAALLEAADIGHMVADSHISALEGSIGVLPRRILVLEEDEIRTRRLLTEAGFADVLRRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUH6</accession>
    <name>A8HUH6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="13">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="13">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">thrS</name>
        <name evidence="16" type="ordered locus">AZC_0947</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="13"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0947"/>
    <dbReference type="EnsemblBacteria" id="BAF86945">
        <property type="protein sequence ID" value="BAF86945"/>
        <property type="gene ID" value="AZC_0947"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0947"/>
    <dbReference type="eggNOG" id="COG0441">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008554_0_1_5"/>
    <dbReference type="OMA" id="FYYDFAY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13 16" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 13" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="15">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="240"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="500"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAF86945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="636" mass="71863" checksum="21A560F18280E216" modified="2007-12-04" version="1">MAAAISKSLLKKAVAVTLDGALTDLSEPITKDARIEIVTRDDPRALELIRHDAAHVLAEAVQELFPGTQVTIGPVIENGFYYDFARNEPFTTDDLPKIEAKMKEIIARDKPFTKEVWSRDEAKRVFRDKGEAFKVELVDAIPEDQDVKIYKQGEWFDLCRGPHMPSTGKIGTAFKLMKVAGAYWRGDSNNPMLTRIYGTAWKDQSELDAYLHRLEEAEKRDHRRLGREMDLFHFQEEGPGVVFWHPKGWSLFQGLVSYMRRRLKADYNEVNAPQVLDKSLWETSGHWGWYKENMFKVQSAGEETGDERVFALKPMNCPGHVQIFKHGLKSYRDLPLRLAEFGAVHRYEPSGALHGLMRVRGFTQDDAHVFCTEEQMAAECLKINDLILSTYADFGFEEITVKLSTRPEKRVGSDAVWDHAEDVMSRVLKQIEAESGGRIKTGILPGEGAFYGPKFEYTLSDAIGREWQCGTTQVDFNLPERFGAFYVDADGQKKTPVMIHRAICGSMERFTGILIEHFAGHFPLWLAPVQLAVCTITQEADDYAAEVASAARALDLKVELDTRNEKISYKVREHSLAKIPVQFALGKKEAAERTVSIRRLGSQEQKVLPLEEALKLLADEAVPPDLKRRAAVTKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUP2</accession>
    <name>A8HUP2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0968</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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                <person name="Aono T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Backer P.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0065 (bug) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4334"/>
    <dbReference type="EnsemblBacteria" id="BAF90332">
        <property type="protein sequence ID" value="BAF90332"/>
        <property type="gene ID" value="AZC_4334"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4334"/>
    <dbReference type="eggNOG" id="COG3181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045683_1_0_5"/>
    <dbReference type="OMA" id="APGSMDH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005064">
        <property type="entry name" value="BUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042100">
        <property type="entry name" value="Bug_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42928">
        <property type="entry name" value="PTHR42928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03401">
        <property type="entry name" value="TctC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="386" mass="39789" checksum="FD66B4B6C20F9F9B" modified="2007-12-04" version="1">MRHVHEGAKSGVPALRPLPFATEAVNSFPNVRHLEVKRRSGPHVRHGKEIMPQFSHGPRALSARPSRRAVAALGLALLAAPLAALPARAQVADLRIMAPAAPGGGWDQTARSMQQALVAAGAARSVQVTNVAGAGGTIGIAQFVNGAKGDPNQLMVMGYVMVGAILTNKAPVTLDQVTPIARLTEETEAIAVPAASPIKTVQELAEAIKANPAKVTWAGGSAGGVDHIAAALFAQAAGADPSKINYIPFSGGGEALAAVLGGKVTAGISGYGEFESQVKAGKLRILAVTAGERVEGVDAPTLTEAGLKLKITNWRGVVAPPGLNPEQVKTLTATVEKMAKSPAWAEVLKQKGWDDALLTGEAFTAFLKQENATTTDILKSVGLVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVR3</accession>
    <name>A8HVR3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutathione synthetase</fullName>
            <ecNumber evidence="10">6.3.2.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GSH synthetase</fullName>
            <shortName evidence="10">GSH-S</shortName>
            <shortName evidence="10">GSHase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Glutathione synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gshB</name>
        <name evidence="13" type="ordered locus">AZC_4348</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + glutathione + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13557"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="10">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic GSH synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.3" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172868.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4348"/>
    <dbReference type="EnsemblBacteria" id="BAF90346">
        <property type="protein sequence ID" value="BAF90346"/>
        <property type="gene ID" value="AZC_4348"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4348"/>
    <dbReference type="eggNOG" id="COG0189">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068239_0_0_5"/>
    <dbReference type="OMA" id="WMRKDPP"/>
    <dbReference type="OrthoDB" id="878336at2"/>
    <dbReference type="UniPathway" id="UPA00142">
        <property type="reaction ID" value="UER00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004363">
        <property type="term" value="F:glutathione synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00162">
        <property type="entry name" value="GSH_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006284">
        <property type="entry name" value="Glut_synth_pro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004218">
        <property type="entry name" value="GSHS_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004215">
        <property type="entry name" value="GSHS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21621:SF4">
        <property type="entry name" value="PTHR21621:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02955">
        <property type="entry name" value="GSH-S_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02951">
        <property type="entry name" value="GSH-S_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01380">
        <property type="entry name" value="glut_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="125"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF90346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="314" mass="35087" checksum="CEF4958F59781D75" modified="2007-12-04" version="1">MSLQVAVQMDHIAHINIAGDSTFALLLEAQRRGHRLVHYTPDRLAMRDGAVFATVEDLTVADEAGKHFTLGEKRRVKLSDYDVVLLRQDPPFDMAYVTTTHLLERIHPKTLVVNDPAHVRNAPEKIFVTEFPELMPPTLITRDLEEIKAFRAEFKDVVMKPLYGNGGAAVFRMAEGDLNFGSLYDLFSTTFREPWVIQRFLPEVKHGDKRIILVDGEAAGAVNRVPSEGDLRSNMVRGGAARPTDLTDREQEICARIGPSLRKMGLIFVGIDVIDGNLTEINVTSPTGLRAIKRLGGPDIAAQIWDKIEEKRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8HW36</accession>
    <name>A8HW36_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-aspartate dehydrogenase</fullName>
            <ecNumber evidence="6">1.4.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nadX</name>
        <name evidence="9" type="ordered locus">AZC_4388</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="6">Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.</text>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
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        <text evidence="6">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.</text>
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        <text evidence="6">The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.</text>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <location>
            <begin position="403"/>
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
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        <property type="protein sequence ID" value="BAF87505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1507"/>
    <dbReference type="EnsemblBacteria" id="BAF87505">
        <property type="protein sequence ID" value="BAF87505"/>
        <property type="gene ID" value="AZC_1507"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1507"/>
    <dbReference type="eggNOG" id="COG5265">
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    <dbReference type="HOGENOM" id="CLU_000604_84_1_5"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC1_TM_dom"/>
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        <property type="entry name" value="ABC1_TM_sf"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
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        <property type="entry name" value="PTHR24221"/>
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    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="56"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="76"/>
            <end position="96"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="324"/>
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    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="37"/>
            <end position="329"/>
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            <end position="597"/>
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        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="396"/>
            <end position="403"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
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    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF87505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="640" mass="71074" checksum="88D1BD5ADA35B454" modified="2007-12-04" version="1">MFKGVSAARGALGKTIAALWPYLWPVGRPDLKRRVMATTVLLFLAKFATMAVPFIFKWATDALAHVPDGQGDPDISWLLAAPVLLTLAYGFSRIVMAGITQLRDGMFAAVALHAVRRLATETFEHMHALSLRFHLERKTGGLTRVLERAREGIETIVRMLVLQLAPTIVEMVLVLAVLLFAFDWRYVVAVSLTVALYTWFTYAASEWRIAIRRDMNESDTEANTKAVDSLLNYETVKYFGAETRERNRYDRSMARYEQATVRTFTSLAWLNAGQAFIFTLGLTAVMVMAAYDVRAGRQSLGAFVMVNAMMIQLYQPLNFLGMIYREIKQAIVDIEAMFAVLARDPEIEDRPDAPALKIAGGTVRFEDVRFAYDPDRDILKGVTFEVPAGRTLAIVGSSGAGKSTISRLLFRFYDVKGGRITIDGQDIRDVSQDSLRAAIGMVPQDTVLFNDTIAYNIRYGRADATEAEVEEAARLAQIDAFIRATPKGYKTEVGERGLKLSGGEKQRVAIARTILKAPPILVLDEATSALDSHTEREIQDALDRVSRGRTTLVIAHRLSTVINADEILVLSQGRVAERGTHPELLAKGGLYAALWQRQREADDARKKLLEAAASPEPEAEPQREEPHLVAHREEEPSSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXJ9</accession>
    <name>A8HXJ9_AZOC5</name>
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        <recommendedName>
            <fullName evidence="5">CDP-diacylglycerol--serine O-phosphatidyltransferase</fullName>
            <ecNumber evidence="4">2.7.8.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphatidylserine synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_1510</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16913"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="2.7.8.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.8" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170038.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1510"/>
    <dbReference type="EnsemblBacteria" id="BAF87508">
        <property type="protein sequence ID" value="BAF87508"/>
        <property type="gene ID" value="AZC_1510"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1510"/>
    <dbReference type="eggNOG" id="COG1183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049944_1_0_5"/>
    <dbReference type="OMA" id="IFFDFFD"/>
    <dbReference type="OrthoDB" id="1232102at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003882">
        <property type="term" value="F:CDP-diacylglycerol-serine O-phosphatidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004533">
        <property type="entry name" value="CDP-diaglyc--ser_O-PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012616">
        <property type="entry name" value="CDP-OH_P_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08009">
        <property type="entry name" value="CDP-OH_P_tran_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00473">
        <property type="entry name" value="pssA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="CDP-OH_P_tran_2" evidence="10">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="271" mass="29372" checksum="EE0052B560936953" modified="2007-12-04" version="1">MTLPFPPFDPNGQSTERPRRFARIPLRLLLPNMVTLLALCSGLTAVRMAIEHRMELALAAIVFAALLDGVDGRLARALKGTSRFGAELDSLADFVNFGCAPALILYLWGLDEAGSLGWIGALIFAICAALRLARFNVMLDDPNRPAFTADFFTGIPAPAGAITVLLPVYLELLGIPHVTLSAPMALIYCLAIGVLMISKVPAWSGKTLGKRVRRDMVLPLFVLFAVFAGLLASYPWLVLSVCSVLYLAMLPLSALRYRRLMAEHVAGLPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYX4</accession>
    <name>A8HYX4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <dbReference type="EnsemblBacteria" id="BAF90551">
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    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
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    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="340" mass="37396" checksum="297A00C8A629FDBD" modified="2007-12-04" version="1">MKKIGFLSFGHWTPSPNSGTRSAGDALLQSIDLAVAAEELGADGAYFRVHHFARQLASPFPLLAAVGARTSRIEIGTAVIDMRYENPLYMAEDAGAADLIAGGRLQLGISRGSPEQVIDGWRYFGYQPAEGQSDADMGRRHAEVLLDVLKGEGFAKPNPRPMFPNPPGLLRLEPYSEGLRERIWWGAGSNATAVWAAERGMNLQSSTLKDDETGEPFHIQQAKQIRVYRDAWKAAGHDREPRVSVSRSIFALVDERDRAYFGRGNESADQIGFLDEKTRAIFGRSYAATPDVLIEELRKDEAIAEADTLLLTVPNQLGVDYNAHVIEAILKHVAPALGWR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87229.1"/>
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        <location>
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        </location>
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        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87229.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="349" mass="37694" checksum="4123EAF482CE2447" modified="2007-12-04" version="1">MKRLSFKHGAAASLACLAGLLGLIGGAQAQQTFYVAGYGGTFEQIMRKEIIPAFEKAHGVKVEYVAGNSTDTLAKLQAQKGNQQIDVAILDDGPMYRAINLGFCAPIKGLPTAELFDTARFKDDKAVGIGLVATGLMYNTKVFKEKGWAPPTSWNDLKDPKYKGQLVIPPINNTYGLYTLVEFARMNGGGENAIEPGFKVMKTDVNPNVLAYEPSPGKMTELFQSGQAVIAVWGSGRVASFAATGFPVDFVYPKEGAVALLASACPVGKGGDNALANAFVQAMVAPEFQAVLSREYGYGPVNKNAKVDMEALRMAPVGERAAKLLVFDWDAINPKIDDWTKRWNREVER</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        </source>
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    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4 10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169799.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1268"/>
    <dbReference type="EnsemblBacteria" id="BAF87266">
        <property type="protein sequence ID" value="BAF87266"/>
        <property type="gene ID" value="AZC_1268"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1268"/>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000404_0_1_5"/>
    <dbReference type="OMA" id="WACADPG"/>
    <dbReference type="OrthoDB" id="357568at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013678">
        <property type="entry name" value="RNR_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08471">
        <property type="entry name" value="Ribonuc_red_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="8 10" id="KW-0170">Cobalt</keyword>
    <keyword evidence="7 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuc_red_2_N" evidence="12">
        <location>
            <begin position="31"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="11">
        <location>
            <begin position="198"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="11">
        <location>
            <begin position="791"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF87266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1241" mass="135233" checksum="2748610D5F3B275C" modified="2007-12-04" version="1">MRVERRYTTEGRSPYDAIAFREAVSEIRNPNGSVVFRQEGIEVPAQFSQVASDILAQKYFRKAGVPARLKKVEENAVPSFLWRSVPDEAALAALPEKERYVGESSAKQVFDRLAGTWTYWGWKGGYFDTEADAQAFFDEHRYMLAMQMVAPNSPQWFNTGLHWAYGIDGPGQGHFYVDYKSGELLASTSAYEHPQPHACFIQSVGDDLVNEGGIMDLWVREARLFKYGSGTGSNFSALRGEGERLSGGGKSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVVVDADHPDIESYVNWKVLEEQKVASLVTGSRINAKHLKAVLKACVNCEGTGDSCFDPEKNPALKREIKAARKAGVVDAAIRRVIQYARQGFTDIDVAIYDTDWDGEAYLTVAGQNSNNSVRVTDDFLRAVEEDADWNLIRRTDGKVHKTVKARELWDKIGSAAWHCADPGIQFHTTINDWHTCPSGGEIRASNPCSEYMFLDDTACNLASLNLLQFRDSEKRFDVESFEHAVRLWTVVLEISVLMAQFPSRRIAELSYEYRTLGLGYANIGGLLMTAGIPYDSAEGRAICGAISAIMTGICYATSAEMAKELGPFPAYEQNATSMLRVIRNHRRAAYGEAKGYEGLSIAPVPLDHASCKDERLVAHAKAAWDKALADGEKHGYRNAQVSVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINGAVPEALRTLGYSEAQIAEIEAYAVGHGSLAQAPAINHGSLKAKGFDAEAIAKAEAAVKTAFDIKFAFNRWTFGDDFLTKSLGVSAAQLADPKFDLLSHLGFSKADVEAANVHVCGAMTLEGAPYLKAEHLPVFDCASPCGRIGKRFLSVESHIRMMAAAQPFISGAISKTINMPNEATVEDCLSSYLLSWRLALKANALYRDGSKLSQPLNAQLVADDEDEEDAVEALVAQPAAARAATVTEKIVERVIERVIERNVHDREKMPDRRKGYTQKAVVGGHKVYLRTGEYDDGRLGEIFIDMHKEGAALRSFINNFAISVSLGLQYGVPLEEYVDAFTFTRFEPAGPVQGNDTIKYATSILDYVFRELAVSYLGRYDLGHVDQTETGFDALGKGVDEGKAPTGGAAAAAASRVVSKGLVRGKNVSLLVPQLAEPRASSDNVTVLRARTEGATALKPEAELEEGAAELEEAVESLLDKPLAWTPAARTQDRRAEARARGYEGEACPECMNFTMVRNGTCLKCNTCGATTGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1R4</accession>
    <name>A8I1R4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1412</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169940.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1412"/>
    <dbReference type="MEROPS" id="M38.982"/>
    <dbReference type="EnsemblBacteria" id="BAF87410">
        <property type="protein sequence ID" value="BAF87410"/>
        <property type="gene ID" value="AZC_1412"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1412"/>
    <dbReference type="eggNOG" id="COG0402">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_3_5"/>
    <dbReference type="OMA" id="RVFWSYA"/>
    <dbReference type="OrthoDB" id="1592010at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="57"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="456" mass="48525" checksum="2D51FE03FB17B428" modified="2007-12-04" version="1">MARPSRTLITGATILSMDGAVGDLPKGDILVEDDRIIAIAPVLQADDAERVDAEGRIAVPGFVNAHMHTWQTGLRSLAADWTLLEYFRWVHAGLATRFRPEDIGIATLVGALGQIDAGTTTLVDWCHNNPTPEHTDAAVEALARSGIRAAFFHGSPKPDPKPGEPHFSEVPHPRAEIERLRRGMFSGEDGLMTLGLAILGPHYSTLEVARADFRMAREFGLVASMHQGGGAAKTPGGWETLLDEGLVGPGINVVHGNDLSDALFSALVDQGASFSVTPENEMTQGHGFPVTGRLLKRGVAPSLGVDLESVLAGDMMGVARVALGMQRVLDNTDSRRDTGAIPPTSTVRVRQALEWITIEGARMLGQEGRIGSLAPGKQADITLIDARALHLQPVHDPVATVVMQAGRGDVEAVMIAGRFRKKNGKLLAAALDDTLARLARSGARIVDELGLKRTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2C1</accession>
    <name>A8I2C1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fructose-1,6-bisphosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1849</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FBPase class 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170377.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1849"/>
    <dbReference type="EnsemblBacteria" id="BAF87847">
        <property type="protein sequence ID" value="BAF87847"/>
        <property type="gene ID" value="AZC_1849"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1849"/>
    <dbReference type="eggNOG" id="COG1494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054938_0_0_5"/>
    <dbReference type="OMA" id="AVFYMDK"/>
    <dbReference type="OrthoDB" id="879338at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004464">
        <property type="entry name" value="FBPase_class-2/SBPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30447">
        <property type="entry name" value="PTHR30447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03320">
        <property type="entry name" value="FBPase_glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004532">
        <property type="entry name" value="GlpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00330">
        <property type="entry name" value="glpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="94"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="171"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="193"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR004532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004532-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="327" mass="33871" checksum="E40E5428A7A11736" modified="2007-12-04" version="1">MSRVPPQLDRRLALELARVTERAAVAAAVYRGRGDEQAADEAAANGAFSELCDMPISGEVVIGPGLEGEVAHLFQGETVGRGGEAVEIAADALEGTTLCAKNMPGSMSVMVMAAPGALLKVPPVYMDKVAVGPGYPKGVVSLAAKPEENIRALAEAKGVPPTEITALVLDRPRHAGLIAAVRAVGASVKLITDGDVAGIIHTTDPAGSGVDIYLGIGGAPEGVLAAAALRCIGGQMEGRLILDSEDKRSLAKKLGIRDGSKVYGLEDMVQGDCIVSATGVTDGALLHGVRMLRGRVVTETLLMRAATGTVRRISTEHRDPQKFNIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2F4</accession>
    <name>A8I2F4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="8">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">AZC_1865</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8 11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8 11">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="entry name" value="SSF53474"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
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        <location>
            <begin position="41"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="303" mass="33568" checksum="2A8E5EE0969B7DAA" modified="2007-12-04" version="1">MIEARDRTMQEKLTFMSDGLKLSAVLHVPEGRRPDERLPAFIVLHGFVGSKDESHAEIQARMLEDFGYVALRFDFRCCGESEGERAQVRCFDQVADAKNALTFLAGRPEVDPARIGVVGHSFGAAVAVYSAGVDSRFACVISSCGWGDGERKFRGQHPTPEAWARFTGLLEAGRKHKRETGQSMWISRFDAVPIPEPLRRNLSPKAIMEIPVETAISMYEFRADDVVGNIAPRPALFFHTADDGITPTEQSIRMFEKAGQPAELMLITGTSHFPLSEQDAPRTKLMIRGWLDKFFPSPLGGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I399</accession>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1998"/>
    <dbReference type="EnsemblBacteria" id="BAF87996">
        <property type="protein sequence ID" value="BAF87996"/>
        <property type="gene ID" value="AZC_1998"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1998"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_8_1_5"/>
    <dbReference type="OMA" id="KRWFARQ"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="FAD-bd"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="4">
        <location>
            <begin position="51"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="434" mass="47050" checksum="A64024C845D710D5" modified="2007-12-04" version="1">MHRRRAETMRPQDALARCRYDPRNFRRRTASIVCPKEAFMSQPVSNAPGIEAEVAVVGAGPAGLATAIGFAASGRTTVLITGPERGIDHRTTALLGTSIPILERFGVWDRIAPHTAPLRDMRIVDGTRRLVRAPEVTFKASEIGLEAFGYNIENEPLRRELGAAAEETNGLSLARASLTDLRTDADGVTLSLDDGRSVRATLVVAADGRNSRVREACGIGVKRREYPQVAVTATVRHTRPHWDISTEFHTETGPFTLVPLPGDRSSIVCVVDDREAVRLLGLDLPALAREFERRAHSILGPFEVEEGRAAFPLVAETAREITAPRVALMAEAAHVMPPIGAQGLNLGLRDAVALVDLAAEPGLDLGGAEMLKRYAGARDRDIHGRMTAVDMLNRSLLSDLVPVQSVRGFGLYLLDRVGPLRRTVMRLGLGNRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3I5</accession>
    <name>A8I3I5_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Putative oligopeptide ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2027</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170554.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2027"/>
    <dbReference type="EnsemblBacteria" id="BAF88025">
        <property type="protein sequence ID" value="BAF88025"/>
        <property type="gene ID" value="AZC_2027"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2027"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_5_2_5"/>
    <dbReference type="OMA" id="AIPSKMF"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="79"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="280" mass="29661" checksum="9169A7879E24985D" modified="2007-12-04" version="1">MSTRLLTLPRVGYQISPVGIGAFLVILFWLVVAIFAPRLTPYAIGDIVDFDYFGPVSAKFWMGTDYLGRDMLSRIIAGSRYTVGLSLAAVAIACCTGVTLGMTAAVIGGWFDSILSRFLDALSSIPSKLFGLVVVAGIGSSIPVLIGTLAIIYTPGSYRFARALAVNINTMDFVTVARTRGEGVAYLIGSEILPNIVGPVFADVGLRFVFIVLLLSGLSFLGLGVQPPNADWGALVRENISGLAFGAPAVIFPSLAIASLTISVNLLIDNLPRKIRDRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3N2</accession>
    <name>A8I3N2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1634</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1634"/>
    <dbReference type="EnsemblBacteria" id="BAF87632">
        <property type="protein sequence ID" value="BAF87632"/>
        <property type="gene ID" value="AZC_1634"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1634"/>
    <dbReference type="HOGENOM" id="CLU_321516_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="792"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="833"/>
            <end position="862"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="901" mass="97319" checksum="ED2B32D2C02B24D0" modified="2007-12-04" version="1">MTIGRRARSDPPSHEEMAAAGAGEIELHHEVVIVVVAAAIEVFPAPRVHAVVPQMPHVRAVDHFVGIGEGIEGVPAGRELHGNEIARIHVQKGTLAIAAEAGAGEHRAAVARHIGAGIAGGVIARIAGLEAADAAGIIVHLVESDVLVLRAPLAHPHDGGLVVGGTDGLRDGHSLRHMNGTGARGGNEIHETGGRGGAALGRRGGSAADADGHHAAGGNPHLRDRRLRLMIEHLDQVRREVLLEGLLGELGGPGMGIARLPRKAVADAAHGHLHRRVRSQHGLEQQALRHGRDIARSDVQHVRRVEIGLPLQERADRPCQQQVIGLPEVRHRVIAGPAGGTATEIEPRPDACEGARRDHGCLHDQIQNIARRHKLLIGQRRRDTRAGVIRDPRPVVIRCRVQGREHQVHHRAGIGVEFLEPGTDERLDDAEIPALREPHRLGGGCGRERRDGRIDPARQRDACLQARGLECRTLGINAETGIGRGSSGLIEGVEQEQRHRLAVVRALHAVQPGEDLRVNGRLIVDRRRVVDRRISGFAHIDVHVSAERIGEALEIGRNRREIRGGHRPERCRLRVLIVHHIGRIVVPAAAPVALDVAGRGVRDRISVIRDGCGDRNIAKARSRHGGLEIGEGRIDPALIAGKARIARRRTIHVQLVAQQDAPQMRLNIRHAPEGGDEHLDPLVGIGGAVHQPGRPRRAISALNDRALVGAHHQFDIRGPHHIGDDLLLRPVHHRRGTKAVVIGADEAEVLGDLVQISGDGIAGPPDFPALVIDADIVAEGRVGGHEVHIRHRHLSTRAGPPPPPEGNAEPHDHPDMVPQAWLAVVKIACRTRADTPPPAASPRKRPHRSAAPIPDARRNPSRTTWLPGFARWIRERKVADTETITLTRRCHGSVSRRATCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3Z4</accession>
    <name>A8I3Z4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170199.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1671"/>
    <dbReference type="EnsemblBacteria" id="BAF87669">
        <property type="protein sequence ID" value="BAF87669"/>
        <property type="gene ID" value="AZC_1671"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1671"/>
    <dbReference type="eggNOG" id="COG1905">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054362_1_2_5"/>
    <dbReference type="OMA" id="VGKFHVQ"/>
    <dbReference type="OrthoDB" id="1206880at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01958">
        <property type="entry name" value="nuoE_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01099">
        <property type="entry name" value="COMPLEX1_24K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <reaction evidence="5 10">
            <text>2 H(+) + H2O + urea = CO2 + 2 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20557"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16199"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7 10">
            <name>Ni cation</name>
            <dbReference type="ChEBI" id="CHEBI:25516"/>
        </cofactor>
        <text evidence="5 7 10">Binds 2 nickel ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Carbamylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Carboxylation allows a single lysine to coordinate two nickel ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.5" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012170294.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1766"/>
    <dbReference type="MEROPS" id="M38.982"/>
    <dbReference type="EnsemblBacteria" id="BAF87764">
        <property type="protein sequence ID" value="BAF87764"/>
        <property type="gene ID" value="AZC_1766"/>
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    <dbReference type="KEGG" id="azc:AZC_1766"/>
    <dbReference type="eggNOG" id="COG0804">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000980_0_0_5"/>
    <dbReference type="OMA" id="GFDSHIH"/>
    <dbReference type="OrthoDB" id="157757at2"/>
    <dbReference type="UniPathway" id="UPA00258">
        <property type="reaction ID" value="UER00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:urease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043419">
        <property type="term" value="P:urea catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01953">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
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    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
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    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
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        <property type="entry name" value="Urease_alpha_N_dom"/>
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        <property type="entry name" value="Urease_AS"/>
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    <dbReference type="InterPro" id="IPR005848">
        <property type="entry name" value="Urease_asu"/>
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    <dbReference type="InterPro" id="IPR017951">
        <property type="entry name" value="Urease_asu_c"/>
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    <dbReference type="InterPro" id="IPR029754">
        <property type="entry name" value="Urease_Ni-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01752">
        <property type="entry name" value="UREASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01792">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01120">
        <property type="entry name" value="UREASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00145">
        <property type="entry name" value="UREASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51368">
        <property type="entry name" value="UREASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 7" id="KW-0533">Nickel</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urease" evidence="12">
        <location>
            <begin position="132"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5 8 9">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="5 7">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 9">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="5 6">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR611612-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF87764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="571" mass="60689" checksum="E1165CE0AB925285" modified="2007-12-04" version="1">MTKARMSRSAYAHMFGPTVGDKVRLADTALYIEIEKDFTVHGEEVKFGGGKVIRDGMGQSQVANADGAVDTVITNAVILDHWGIVKADVGLKDGRIFKIGKAGNPDVQSGVDIIIGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALASGVTTMLGGGTGPATGTFATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASQPKALEEMVRAGACALKLHEDWGTTPAAIDTCLSVADAFDIQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSSTNPTRPYTRNTIDEHLDMLMVCHHLSPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGESGGNDNLRARRYVAKYTINPAIAHGVSKHIGSVEAGKLADLVLWSPAFFGVKPDLVLKGGSIAVAQMGDPNASIPTPQPVHYRPMFGAYGRARTHSSLTFVSKAAVEDGLAARLQTAKTLVAVENVRSGISKKDMVLNGATPHIEVDPETYDVRADGELLVCEPADVLPMAQRYFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5N4</accession>
    <name>A8I5N4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-keto-4-pentenoate hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170855.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2328"/>
    <dbReference type="EnsemblBacteria" id="BAF88326">
        <property type="protein sequence ID" value="BAF88326"/>
        <property type="gene ID" value="AZC_2328"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2328"/>
    <dbReference type="eggNOG" id="COG0188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002977_6_1_5"/>
    <dbReference type="OMA" id="THHWLLF"/>
    <dbReference type="OrthoDB" id="217468at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="term" value="F:DNA binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="10">
        <location>
            <begin position="20"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="891"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="560"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="899"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="917" mass="101448" checksum="D95B6838174B5523" modified="2007-12-04" version="1">MADNDTPPQGGATPSDIRPVSITDELSRSYLDYAMSVIVARALPDVRDGLKPVHRRILFSMHENGYEWNKQYRKSARVVGDVIGKYHPHGNQSVYDALVRMVQTFSMRVPLIDGQGNFGSVDGDPPAAMRYTEVRLEKVTQSLLDELGQDTVDFQANYDNSENEPSVLPARFPNLLVNGAGGIAVGMATNIPPHNLGEVIDGTVALLDDPVMDPELLLDYIPGPDFPTGALIMGRSGIRQAYMTGRGSIMMRARATIETVRKEREAIIITEIPYQVNKATMIEKIAELVRDKRLEGIAEIRDESDREGMRVVIEVKRDAQADVVLNNLYRMTPLQTSFGVNMVALSGGRPAVMTLHDTLTAFIAFREEVVSRRTKFLLRKARDRAHVLVGLAIAVANIDEIIQLIRTAPDPGTARERLMERHWPAKDVASLVALIADPRHVVASDGTYRLSMEQARAILDLRLQRLTALGRDEISDELDKLALEIAEYLEILASRPRMRAIIREELLALRAEFNTPRRTEITEGFGDLDDEDLIAREDMVVTVSHAGYVKRVPLSTYRAQRRGGKGRSAMQTRDEDFVTRLFVASTHAPVLFFSSKGQVYKLKVWRLPAAAPQARGKALINILPLQPDERITSIVPLPENLEEHSLWQIMFATTGGTVRRNALADFSQVNRNGKIAMKLEEGEQIASVQLCNEHQDVLLTTANGACIRFPVPEVRLFKGRDSVGVRGIRLEEGDRLISMAIINHTDAAAEERVQYLRQSRAQAAEDAPIELEGEAPAAEGKLDPVKFLEMETNEQFILTLSENGYGKRTSSYEYRVTGRGGKGIVAMAVNERNGKLVASFPVRDADQIMLVTDGGQLIRCPVNGIRIVGRSSQGVIVFDTAADERVVSVEHISEDEAGEATEGEGEETGAPDESPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I649</accession>
    <name>A8I649_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2363</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2363"/>
    <dbReference type="EnsemblBacteria" id="BAF88361">
        <property type="protein sequence ID" value="BAF88361"/>
        <property type="gene ID" value="AZC_2363"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2363"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="WTVLMIT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="69"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="14"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="108"/>
            <end position="115"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="333" mass="35325" checksum="9F631C4862F39843" modified="2007-12-04" version="1">MRVMAASVNFQRPIRSGDLPHPGLRRQSGWLTSRPQSAGLDPGTGGNMTGLNTAAPGALQAAAGAAPAAQLDGVRISFPASGPRGAEFIAVEGASLTVADGEFVAIVGPTGCGKSTLLNATAGLLVPSVGSVSIFGAPLKGLNRSAGYLFQAEALFPWKTVIDNVAIGLDVAGVPTAQARERAAAWLKRVGLGAFADRYPHMLSGGQRKRVGLAQVLIRDPKILLMDEPFGPLDAQTRQIMGNLLLDLWTQDRKAVLFVTHDLDEAIALADRVVIMSAGPASRIIGEWRIGLARPRDIAEVRLLPEFHALHREIWGALREEVVKGYRQTEEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A8I684</accession>
    <name>A8I684_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_2376</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2376"/>
    <dbReference type="EnsemblBacteria" id="BAF88374">
        <property type="protein sequence ID" value="BAF88374"/>
        <property type="gene ID" value="AZC_2376"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2376"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_1_2_5"/>
    <dbReference type="OMA" id="CFGTSGP"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="8"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="198"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="400"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="589" mass="64532" checksum="B54E71F071E5EB60" modified="2007-12-04" version="1">MDDMTKEMTGAEMVIQALTDQGVEHLFGYPGGAVLPIYDALFHQNRIEHILVRHEQAAVHSAEGYARSSGKVGVVLVTSGPGATNAVTGLTDALMDSIPIVCITGQVATHLIGNDAFQECDTVGITRPCTKHNYLVRDVNDLARVLHEAFYVAQNGRPGPVVVDIPKDVQFAKGTYIGRENIEHKTYKPRLVGDDGAVRQAIEMIAGAKRPIFYTGGGVINSGPAASRALRELARLSGVPVTSTLMGLGAFPAASSQWLGMLGMHGTYEANMAMHGCDVMVCIGARFDDRITGRLDAFAPGSKKIHIDIDPSSINKNVKVDLPIIGDCTKVLEAMVALWKSQDRQTDKAALDEWWKQIDRWRARNSLAYRLLPDVIKPQQAIERLYAATKDKDVYITTEVGQHQMWAAQFFRFEEPNRWMTSGGLGTMGYGLPAAIGAQIAHPDGLCIDIAGEASILMNMQEMSTAVQFNLPVKIFILNNRYMGMVRQWQELLHGGRYSHSYSEALPDFVKLADAYGGVGIRCEKPGDLDGAIQEMINIKRPVIFDCIVDQQENCFPMIPSGRAHNEMILGDMAVDLDEAITDEGKMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6L7</accession>
    <name>A8I6L7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphogluconate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">edd</name>
        <name evidence="7" type="ordered locus">AZC_2424</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_5"/>
    <dbReference type="OMA" id="WRGVRTD"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="920"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="970"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1016"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1092" mass="116243" checksum="8096892DB7CD6EB1" modified="2007-12-04" version="1">MNISAPFIRRSVATTLLTIGLGLSGLLAYFNLPVAPLPQVDIPTIQVSASMPGASPDTMASTVATPLERHLGQIADVSEITSNSTLGQTRITLQFGLSRDIDGAARDVQAAINAARADLPAALRSNPTYRKVNPADAPVMILSLTSDTLSRGQLYDSAATVLQQKLSQVKGVGQVTIGGSSLPAVRVEINPSALSQYGIGLEDVRAALAAANANSPKGAIESKGQRWQIYTNDQASKADAYRSLIIAYRNNAPVRISDVATVEDSVENIRNEGLANGKPSVLILISREPGANIIETIDRVKDLMPELRASIPADITLAIAQDRTATIRASVADVEHALLIAVILVVVVVFAFLRDARAALIPSVAVPVSLLGTFSAMYLLGYSLDNFSLMALTIATGFVVDDAIVVVENVIRHMEAGKSRLEAALAGAREVGFTVLSMSISLIAVFIPLLLMGGIVGRFFREFSVTISVAILVSMVVSLTTTPMMCAYLLRPHRAERPGNRLGRAAERVFKGILAGYARSLDWALAHRLFILLLLGGVVALNVHLFSVVPKGFFPQQDTGMLVGGAQADQSISFQLMRQKLMRFVEIIKSDPAVDSVVGYTGGGQTNSAFVFVSLKPKEERDASADQVIARLRGRLSSVPGATMFLQAMQDVRAGGRQSNAQYQFTLQSDDLALLREWTPKITEALKRNPDLVDVNSDTQEKGLEMQLDINRDTAARLGLSMSQISNTLYDAFGQRQVSTIYAPLNQYHVVMEVAPRYWQDPRTLDDIRISTSGAALAGSLATASVTSQITSTVSSALSAATGTTDTTLDAVRNASTNRIANTTKSGTSTGAAVSTRFSPSIPLSAFASYGPGNAPLAVNHQGLFAAATISFNLPEGKTIGDAVASIQRTMVEIGTPASVHGTFQGTAKVFQQSLSSQPLLILLALATVYVVLGVLYESFIHPITILSTLPSAGLGAVLALIAFNTEFSLIALIGVILLIGIVKKNAIMMVDFALEAERQQGLPPAAAIREACLQRFRPILMTTLAAVFGALPLALASGTGAELRQPLGISIIGGLLVSQLLTLYSTPVVYLWLDRLRGRERRRRLAPAPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6U9</accession>
    <name>A8I6U9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2046</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170573.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2046"/>
    <dbReference type="EnsemblBacteria" id="BAF88044">
        <property type="protein sequence ID" value="BAF88044"/>
        <property type="gene ID" value="AZC_2046"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2046"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_5"/>
    <dbReference type="OMA" id="AKDYPLM"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="99"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="325" mass="35872" checksum="06CB47DDAF8F2283" modified="2007-12-04" version="1">MQTLQFLLWRLAKGILVVLAIVILDFFLIHMAPGDPASVMAGESGATDEAFVQQLRVKFGLDQPLTTQLGLYLWGVVRLDLGFSHRQQMPVLDLVLDRLPATLLLTGAAFVFSLTLGVVLGAWAAAHKGRPLDRIITTVSLVFYAAPLFWMALMAVLIFSVWLDWLPAFGIRDVGGDAGLLDRTLDVARHLVLPAVTLGLFFTAVYVRMTRASMIEVARQDFVKTCRAKGLPERVILRRHVLRNAVLPVVTLAGLQAGQMVGGAVMTETVFAWPGIGRLMYEALIQRDYNLLLGVFVVSAAMVVVFNILTDLVYRMVDPRIEVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7S4</accession>
    <name>A8I7S4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative phage gp25 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170683.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2156"/>
    <dbReference type="EnsemblBacteria" id="BAF88154">
        <property type="protein sequence ID" value="BAF88154"/>
        <property type="gene ID" value="AZC_2156"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2156"/>
    <dbReference type="eggNOG" id="COG3628">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_133204_1_1_5"/>
    <dbReference type="OMA" id="PECGEPG"/>
    <dbReference type="OrthoDB" id="1791538at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="137" mass="15280" checksum="E486B677ED3DCF78" modified="2007-12-04" version="1">MAQAVRYRTGLDRRTGQVLTGWAHVQQSLAVIWTTRFRERVMRLQIGSELRSWLAEDLSPATALGIYADLVVAAHTFEPEYRLTELQFVNATRAGGLALRHSGTYYPEGRFGDYGKAIPIGYGAPVVLAQQVARRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8I802</accession>
    <name>A8I802_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2192"/>
    <dbReference type="EnsemblBacteria" id="BAF88190">
        <property type="protein sequence ID" value="BAF88190"/>
        <property type="gene ID" value="AZC_2192"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2192"/>
    <dbReference type="eggNOG" id="ENOG5033XIJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1136988_0_0_5"/>
    <dbReference type="OMA" id="TYDYFWI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="280" mass="30655" checksum="D2F5E4E7449582D7" modified="2007-12-04" version="1">MRSGGGLPAAFLLLARNRNAVAPHFPPCSPAPPSGWRGSRGMRALISAAVGAAITCGATFGFVAEAAATPARLIILRHGEKSDPYRLCEIGRRRARALVEQYLGRDAQQSFFAPGTAPEAIFTISIHTVETASPLANSWDLPQAFYSVLPVGKAPKLFDSDLAKRTKQAAENLLNNPRFDGKTVVVVWEHNHIADASLPPGRRALTLRQALNLDQLPGVPETWPDNTYDYFWIVDYKPGNPVPVSFRMEKQVFTGKYADLPHNDWGQPEGLDVRETDCEP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I889</accession>
    <name>RS4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsD</name>
        <name type="ordered locus">AZC_2224</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170751.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I889"/>
    <dbReference type="SMR" id="A8I889"/>
    <dbReference type="STRING" id="438753.AZC_2224"/>
    <dbReference type="EnsemblBacteria" id="BAF88222">
        <property type="protein sequence ID" value="BAF88222"/>
        <property type="gene ID" value="AZC_2224"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2224"/>
    <dbReference type="eggNOG" id="COG0522">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_092403_0_0_5"/>
    <dbReference type="OMA" id="NVVFRMG"/>
    <dbReference type="OrthoDB" id="1211060at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
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        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000085959" description="30S ribosomal protein S4">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="S4 RNA-binding" evidence="1">
        <location>
            <begin position="94"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="205" mass="23484" checksum="AC0A9DFBAB628579" modified="2007-12-04" version="1">MSKRISAKHKIDRRMGENIWGRSKSPVNRREYGPGQHGQRRKGKLSDFGVQLRAKQKLKGYYGSIGEKQFHAVYVEASRLKGDTGANLIGLLERRLDAVVYRAKFVPTIFAARQFVNHGHVKVNGRRVNIPSYQVKVGDVIEVREASKQMALVLEAVQLAERDVPDYLEVDHNRLTAKFNRIPELNEVPYPVQMEPNLVVEFYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8H3</accession>
    <name>A8I8H3_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Oligopeptide/dipeptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171186.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2662"/>
    <dbReference type="EnsemblBacteria" id="BAF88660">
        <property type="protein sequence ID" value="BAF88660"/>
        <property type="gene ID" value="AZC_2662"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2662"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_5"/>
    <dbReference type="OMA" id="VNCWLQD"/>
    <dbReference type="OrthoDB" id="1101128at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="330" mass="35461" checksum="3697341E30703A65" modified="2007-12-04" version="1">MAPLLDVRDLSIAFPRATPVRGLSLTVEQGETVALVGESGSGKSLTALALLRLLPAGARIASGEVRFRGEVLSSLPPRALRQVRGRDIAMIFQEPMTSLNPVVTVGQQIIEVVRLHQGLGRAAARARAIELLDLVRIPEPQRRVDEYPHQLSGGMRQRVMIAIAVACSPKLLIADEPTTALDVTIQAQVLDLLDRLRRELNMALLLITHDLGVVAEWADRVVVMYAGRKVEEAPFETLFGTPLHPYTRGLLHASPRLETGLHYTSGRLTEIPGSITTAAGEAGCAFAPRCALARPSCRVVPPDIRPVAAGHLVACPVTTSREVDHAAAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8Y9</accession>
    <name>A8I8Y9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2722</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <sequence length="414" mass="43094" checksum="CC76D6BB7D085BAC" modified="2007-12-04" version="1">MISRPTRVLLGLSLLAGLCGAATAALAAGGLDGLDIRIGRALFNRAWVPAPSSTHADDGLGPLFDARSCASCHPDGRRARTIVTPDGQLDGRGMVLVLMQPGGTGDPVYGRRLQIDAVPGLTPEGILGVADEPLPDGRTARTPAPQQLGYGPLASATGLSLRVAQDLRGRGQLEQVSDAALEKLEAQQAKGPDAVHGRLRRVPAANGKTVIGRYGWKASQPTLASQSAEAFFLDMGMSTSFHPEPWGDCTPVQIACRNAPHGERGEGGLEIPDSILDRVVAYVASLTTPDTEKDPAGARLFAATGCAACHQPALPSRQGGTVRLFTDLMLHDLGEGLADTLPDPGAKPSEWRTAPLAGLSDALARDTGLLHDGRAKSVEEAVLWHGGQAAGAVARFRALPAGQKAALLQYVSKL</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Aono T."/>
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        </source>
    </evidence>
    <sequence length="363" mass="38595" checksum="C2ED3D8819B3C914" modified="2007-12-04" version="1">MAALPFLLRLCLRRGMVPPVGRMTCRSAPVTAFPVRAPAATLADVASAAGVGESTVSRVLRNHGSFSEKTRKRVMEAAAQLGYVPNRIAGTLASSGSRLVGIIVPSLSNIVFPEVLSGVNQALEDEGYQAVFAVSEYKMAREEEMVASMLAWRPAALMVAGLEHTPAARALLEAGGTRIIELMDLDGEPIDIAVGFSNLEVGRVSARHLLARGYRRIAYVGHDLAADTRAAKRLEGFEGVLRDQGLALMERSTLPTLSSIEAGRAGLEQALARRPDLEAVYFSNDDMAFGGYCLCLSRGIRVPDQLALFGYNGLGIGQALPQPLSTIRTPRVEIGATAARLAARNAPAQRIDLGFELIAGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA74</accession>
    <name>A8IA74_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">marR</name>
        <name evidence="3" type="ordered locus">AZC_2473</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2473"/>
    <dbReference type="EnsemblBacteria" id="BAF88471">
        <property type="protein sequence ID" value="BAF88471"/>
        <property type="gene ID" value="AZC_2473"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2473"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_4_0_5"/>
    <dbReference type="OMA" id="FTEQVGH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="43"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="180" mass="20019" checksum="4C1878FD113766A5" modified="2007-12-04" version="1">MSAVVTERRDRHGRSDSVSDDRHRETSTGTADAPHADGPYDFREQVGHLLRKTYQRHLAIFQQHAADPNLTAVQFVTLCALRDNGPSSQSELVRLTAVDQGTIRGIIDRLRARELISLTTDPEDRRKVIATLTDGGRTAIAEMVPCAHRITELTLQNLNAAERVALQFLLRKMLGPDTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAF6</accession>
    <name>A8IAF6_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">ABC transporter substrate binding protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2502</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2502"/>
    <dbReference type="EnsemblBacteria" id="BAF88500">
        <property type="protein sequence ID" value="BAF88500"/>
        <property type="gene ID" value="AZC_2502"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2502"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_841106_0_0_5"/>
    <dbReference type="OMA" id="AKCAHCL"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="67"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="337" mass="35393" checksum="C6476E09C289D751" modified="2007-12-04" version="1">MRPPIKNPEDQDMHRRTFLAGLSGLGASALLPVSGALAQGAAPVTLTVGYAKVAHLAPIILIADKLKAQGVELKLVEFARYADARTALQAGSLDIATVGPADIPISLANGSTALVGIMGVGSSPKYVIARTGTKFESWDDIKGKKIAIAPGSAVWFQFAATLIEKGVPYNSFQAINIQGGGANFDQALEKGEVDAIVTWEPFESIPVMKGYGYFAKNLDYSTSKAAGAELGMLVANKTNIAGKDAAVQAFVSAYVKEMRALEASPAAFATAIQTLTGLDADISKRIAEIIKLGPVVTPDQLKRQAKAFNDLGVIPKDVTGQIDGAWNSTYLDKALKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB59</accession>
    <name>A8IB59_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-binding dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2613</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="388" mass="40386" checksum="8F341508283E99F8" modified="2007-12-04" version="1">MFPGLWPWSGAWSADMWRFLVALGGFTLLAGLLAVAFGSVIFVSTIGNALISTGAIGFTGGVLILASGLILRELERIRAVLAEGARPARATPRVEAVLDDAALLAVSDAVSAPPPRRQPPPVAPEPASEERHAPAPAAEAPPAPEPEYAPMVPPAPEPPQPAPAPELPTPRLRSPSFSDRLRRPMPSLSPERPAPAPASTPGAPTDAAPQPEPPAVTERRGRILGRHGEAEIAPPVPRPRSLLERVALSRPAPERLEPVAPPAPPQPEPEPAPAVAEAAPEPAPAPEPAPAPEPAPEPVHAPEPEAVSHEPAPEPEPAPVPDFAPERAAPRASPRPEPVVLKSGIVGGMAYTLYSDGSIQAELPDGVVRFGSLQELRDHVARAHPPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC71</accession>
    <name>A8IC71_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Sulfate ester transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3169</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3169"/>
    <dbReference type="EnsemblBacteria" id="BAF89167">
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        <property type="gene ID" value="AZC_3169"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3169"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_046113_1_2_5"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
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            <begin position="47"/>
            <end position="70"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="125"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="249"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="274"/>
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    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="98"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="292" mass="31871" checksum="F869FD9FAA9B8AB2" modified="2007-12-04" version="1">MPGRPRPASRRSPQRITMAVLDLPRQAAPHPVSWRRLRPVLAGLRDFAIALALPAVILILWAIGSAYQLVPQQILPPPVYVWENFRDMLASGELLQHASISAARVAGGFVLGASLGLLLGIAMGLSEKVDDYVRPLFTAIAQVPTLGWIPLLMLFLGIGEALKIVIIAKAALVPMVLNTSAGIRGVSKAYLEVADVFAFTRWQKLRRLILPAAVPPIFTGIRYSLTKAWTALVAVELLASAEGLGYLLVWGRQMFWLDTMIVAMVIIGLVGFAMDKLLALVEARLQSWRIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2867"/>
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        <property type="protein sequence ID" value="BAF88865"/>
        <property type="gene ID" value="AZC_2867"/>
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    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Aldolase_TIM"/>
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        <property type="entry name" value="NMO"/>
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        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="68"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88865.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="331" mass="34707" checksum="62DB044DA26D5C67" modified="2007-12-04" version="1">MSTRRPLPPALEGRLRLPVIASPMFIVSGPELVIAECLSGVVGSFPALNARAPDTLDGWLTTIKTRLAEAQAADPGRRIAPFAVNQIVHASNDRLERDMETCVAHEVPLIITSLRPPGDVVRQAHSYGGLVFHDVISVRHAEKALEAGVDGLILVCAGAGGHAGTLSPFALLGEVRRFYDGPIALSGSITTGDAILAAQAMGADFAYMGTRFIATAEANAAARYKEMITESAAADILYTPYFTGVPGNYLKPSIVASGLDPDALPHADKSSMNFGSGRVKAWKDVWGAGQGVGTIGDVPPVAQVVDRLAHEYATARERLAATAARFAGGEA</sequence>
</entry>
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    <accession>A8IDD1</accession>
    <name>A8IDD1_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fkbM</name>
        <name evidence="2" type="ordered locus">AZC_2919</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2919"/>
    <dbReference type="EnsemblBacteria" id="BAF88917">
        <property type="protein sequence ID" value="BAF88917"/>
        <property type="gene ID" value="AZC_2919"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2919"/>
    <dbReference type="eggNOG" id="COG2242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093059_0_0_5"/>
    <dbReference type="OMA" id="IRIFMEF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="53"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="261" mass="29560" checksum="30C42F64E4DEDFA2" modified="2007-12-04" version="1">MDLKIIEYRDHFLKIYGRTGDFYFNDIDIGIQTNNFLLYIIDNHLNDKMYGLDIGANIGLTTAILGKSFPGSSFLSFEPDPQTFGFLQETIVANNLSNCTPYQLALGDRAGELTFMSDPNDSSGNRLAPSGTALGGGNRTVKVDRLDDFLSQEGFPRVDFIKLDVEGYEMEVLRGATKTLRIFRPSVYLEFNSFTLIAFGNHNPRELLDYLRQNFPYVYRFKEGAPLPIQNNQDEMDFIHTNLVHHGCVDDLYCTHTPIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8IE25</accession>
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        <submittedName>
            <fullName evidence="2">Putative methyltransferase</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3027</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_3027"/>
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    <dbReference type="KEGG" id="azc:AZC_3027"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
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    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="87"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="272" mass="30185" checksum="DB5998BDBF2A653B" modified="2007-12-04" version="1">MTSRLFNQMLEGIDRGAFPRTRKWAWRGVYNMLSRFWRDDDWRFMNYGYVPEGVAFPLEAADEPERAFIGLYAQAVDGLPVAGARVLEIGSGRGGGARYVARYHAPASVTGLDYSPETVRLARKLNADTPNLSFEQGDAEHLPFPDASFDIAVNIESSHCYANMPAFVGEVARVLKPGGWFTFADMRGRAAMTELDRQMAVPGLDLVSERNISPRVVAALDAADARKQARIGKALLMKRFMSEFAGAKGSMLYKGLSRGEVIYVARRYRKAG</sequence>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3049"/>
    <dbReference type="EnsemblBacteria" id="BAF89047">
        <property type="protein sequence ID" value="BAF89047"/>
        <property type="gene ID" value="AZC_3049"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3049"/>
    <dbReference type="eggNOG" id="COG4977">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Class_I_gatase-like"/>
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        <property type="entry name" value="DJ-1/PfpI"/>
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    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
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        <property type="entry name" value="HTH_AraC"/>
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    <dbReference type="Pfam" id="PF01965">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HTHARAC"/>
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        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="413" mass="44198" checksum="1D866E67C25F3560" modified="2007-12-04" version="1">MPLLGMRQHASPARLHLGQLRLASGTNATSCSDAPFPLPAVRWSSRVPFHCAGWRDGPAGAAPMSLAPHSVPSRTASGAKLRVGFLPLHNFTLTAFSSFLDVLRLAGDEGDRSRPIACSWAVMAPGRRPVRASCGIEIQPSADLSDPKGFDYMVVVGGLLHGMPPLAPALATYLQQAAQAGVPLIGVCTGSFVLCRLGLMAQRKCCVSWYHYRDFLEEFPALVPVADRLFVIDRDRITCSGGAGVADLAAHLVAAHLGAATAQKALNILLIDRPRTPESAQPAPPVGEGSGADDRVSRALLLMEQNLAEPLSVAEIARRLAVSPRQLERLFAERLAETPQESYLALRLRHGRWMLANTVFSAAQIAAELGFADGSHFGRAFKGRFGETPAAFRKAAVPAGRKGAREPLPRIYD</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <property type="protein sequence ID" value="BAF89472.1"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3474"/>
    <dbReference type="EnsemblBacteria" id="BAF89472">
        <property type="protein sequence ID" value="BAF89472"/>
        <property type="gene ID" value="AZC_3474"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="285" mass="31563" checksum="DFAC5891001EB4D7" modified="2007-12-04" version="1">MTDTSIVGAEQREQFAKQGYTVLRQFYDPKADVAPIHEGIRVILEHVCRKYGVDAPTGTPHEAMTVAYPALIAKNRSWGGEVYDAVKQIPAFMRLVTNLRNDDVFRALREGSVPGLAAGGYGIRIDNPGEEKFRAHWHQEFPSQLRSVDGIVFWTPLLPLTADMGPVEIAEGSHAEGIVPVYEDDKGVGASGTYALHLDREQERLAKYNIVAPLTTPGDLVLMDFLTLHQGGHNKSKTPRWTIQFRYFNFADELGTRIGWRGSFAAGIKFADVLPELLVSRGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEX5</accession>
    <name>A8IEX5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3548</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0065 (bug) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3548"/>
    <dbReference type="EnsemblBacteria" id="BAF89546">
        <property type="protein sequence ID" value="BAF89546"/>
        <property type="gene ID" value="AZC_3548"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3548"/>
    <dbReference type="eggNOG" id="COG3181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045683_0_0_5"/>
    <dbReference type="OMA" id="PMTLIGK"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005064">
        <property type="entry name" value="BUG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042100">
        <property type="entry name" value="Bug_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42928">
        <property type="entry name" value="PTHR42928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03401">
        <property type="entry name" value="TctC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017082">
        <property type="entry name" value="YflP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="356" mass="37027" checksum="CD4CA3A1AEC06BAA" modified="2007-12-04" version="1">MALQQNKVREQGAGSSPGGDTEEDVMFRKTARAALAVLMGAAAFSLAATPRAAQAQAYPARPITVVVPFAAGGPTDTVARLVAESMTKTLGQQVIVENVGGAGGTRGAGQVAKAAPDGYTLLLHHIGQATAPSLYRKLPYKVTDFETAGLITAVPMTLIAKPGFEPKSIADVVAYVKANKDKVTYGNAGVGSASHLCGMLFMSAVGTQVTTVPYQGTGPAMNDLVGGQIDLMCDQTTNTTGQIKGGKVKAYAVTTKEPVKSLPDLPTMEAGGLKGFEVTVWHGLYAPKGTPADVVAKLNAALNTALEDPKVVARFADLGTEPEPKDRRSAEFHKTFLTAEVAKWKPIIEAAGVYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF20</accession>
    <name>A8IF20_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ethanolamine ammonia-lyase small subunit</fullName>
            <shortName evidence="4">EAL small subunit</shortName>
            <ecNumber evidence="4">4.3.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">eutC</name>
        <name evidence="5" type="ordered locus">AZC_3565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ethanolamine = acetaldehyde + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15313"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57603"/>
            <dbReference type="EC" id="4.3.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
        <text evidence="4">Binds between the large and small subunits.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amine and polyamine degradation; ethanolamine degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Bacterial microcompartment</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the EutC family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.7" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172088.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3565"/>
    <dbReference type="EnsemblBacteria" id="BAF89563">
        <property type="protein sequence ID" value="BAF89563"/>
        <property type="gene ID" value="AZC_3565"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3565"/>
    <dbReference type="eggNOG" id="COG4302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068224_1_0_5"/>
    <dbReference type="OMA" id="ADRNCVS"/>
    <dbReference type="OrthoDB" id="1115166at2"/>
    <dbReference type="UniPathway" id="UPA00560"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031469">
        <property type="term" value="C:bacterial microcompartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008851">
        <property type="term" value="F:ethanolamine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00601">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009246">
        <property type="entry name" value="EutC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042251">
        <property type="entry name" value="EutC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042255">
        <property type="entry name" value="EutC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39330">
        <property type="entry name" value="PTHR39330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05985">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018982">
        <property type="entry name" value="EutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-1283">Bacterial microcompartment</keyword>
    <keyword evidence="1 4" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="2 4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="257" mass="27417" checksum="D2E8344506411913" modified="2007-12-04" version="1">MSTKRDPWLGLARHTPARIALGRTGASLPTAEVLKFALAHAQARDAVHTPFDAAATAEGVRALGFETLDVTSAAPARDIYLRRPDLGRRLSDESRTRLAARTDAPIDLALVVADGLSSAAVHAQAVPFLAALKPWIASEGWRTGPVVVAREARVALGDEVGQLLKARAVAVLIGERPGLSSPDSLGLYLTLNPQVGCNDAQRNCISNVRAEGLSHEAAAFKLAWLLKEAFRRSLTGVDLKDESDDFLVDGRPPLRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFL9</accession>
    <name>A8IFL9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ordered locus">AZC_3629</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172152.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3629"/>
    <dbReference type="EnsemblBacteria" id="BAF89627">
        <property type="protein sequence ID" value="BAF89627"/>
        <property type="gene ID" value="AZC_3629"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3629"/>
    <dbReference type="eggNOG" id="COG0364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013524_5_0_5"/>
    <dbReference type="OMA" id="PDEGIQM"/>
    <dbReference type="OrthoDB" id="1153269at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="14"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="191"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF89627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="490" mass="54436" checksum="B7907BA37CD276AB" modified="2007-12-04" version="1">MVARVITVDPFDIVVFGATGDLAKRKLLPALYERDLAGQIPPDARIIGVSRRPMSRGEFQELARDSVEDRDGIDTIEAQRLARFLDRVDYVAVDAVSDEGWTDLKARLSEGGDRVRVFYLAVGPDLFDDICSRIGAHGLVTPQSRVVVEKPVGKNLASARKVNEAVGRVFPEDSIFRIDHYLGKETVQNLMALRFANALFEPVWNNAHIDHVQITVAESIGTAGRAGYYDTAGALRDMVQNHILQLLCLVAMEPPVSMDADAVRDEKLKVLKALVPIDERSAPHLTVRGQYRSGASAGGAVPGYLEELGSPESDTETFVALRAEIANWRWAGVPFYLRTGKRLPSRVSEIVVAFRPIPHSVFDGQAGPIMANRLVIRLQPDEGVKLWLMIKDPGPGGMRLQHVPLDMSFAEAFGVRNPDAYERLLMDVVRGNQTLFMRRDEVEAAWKWIDPILEAWRNSHEPPKPYTAGTWGPSASIALIERDGRTWMDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFY8</accession>
    <name>A8IFY8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="2">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">coaE</name>
        <name evidence="3" type="ordered locus">AZC_0004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <source>
            <dbReference type="EMBL" id="BAF86025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="394" mass="43027" checksum="8188C8891C35CBD7" modified="2007-12-04" version="1">MRYPQIAAAPVNNGLVMKIEPLSAVPSLTSPAAGAAPSERDARRIWADQALRILERDARRSADTHLLPFEAHRLGGIDIYLKDESSHPTGSLKHRLARSLFLFGVCNGQIREGITLVEASSGSTAVSEAYFARLLGLPFYAVMTRTTSPEKIADIEREGGRCHFVDDSSAVYAEAAALAERLGGLYVDQFTNAERVTDWRGNNNIAESIFQQMQGEPRSVPTWIVMGAGTGGTSATIGRYLRYRHHATRLCVADPEGSVFYDAFRTGDRSLTSCPGSRIEGIGRPRVEPSFIPEVIDHMIRVPDAASIAAMRVLARRLGRKVGPSTGTAFHALCMLAAEMMGRGETGSLVTLICDRGERYLRSYYDDAWVAAQGFELGSHEARMETFLDQGGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG57</accession>
    <name>A8IG57_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fkbM</name>
        <name evidence="2" type="ordered locus">AZC_0043</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0043"/>
    <dbReference type="EnsemblBacteria" id="BAF86041">
        <property type="protein sequence ID" value="BAF86041"/>
        <property type="gene ID" value="AZC_0043"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0043"/>
    <dbReference type="eggNOG" id="COG2242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686478_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="38"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="358" mass="39247" checksum="3B01247A98679014" modified="2007-12-04" version="1">MNSNDFGPPANFINGGIYEKENLDVLMSFVRDDTVFLDIGANLGFYSLKVAQRNKLHGKIHAFEPHPTLVRLARASSYLNGFSQLAADDGVIVVHQCALGDTNGEVTLAYPDGHLGGGGMAAAAAGTTAVVTPVHRLDDFLGPDFTFDLAKIDVEGFELEVLRGMQGLIARSPKAVLLFEKLERNRGYEADIEAVLRGAGLHLFGITADSLLFPIADGELSAYSGYVVASHDPDIERNRNHFRIYPRQFLASAERVKERTRDMLVVGGEAGDIIFHGPYWYLHRGIYRLTLEGTTDGIIEVVLAHHFGYPTTSVLLGPDNLTADVLIETDLPQFELVCRPKNNRATVSLKSIRIQRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGX6</accession>
    <name>A8IGX6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0148</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168679.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0148"/>
    <dbReference type="EnsemblBacteria" id="BAF86146">
        <property type="protein sequence ID" value="BAF86146"/>
        <property type="gene ID" value="AZC_0148"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0148"/>
    <dbReference type="eggNOG" id="COG0310">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082057_0_0_5"/>
    <dbReference type="OMA" id="MHIEPGV"/>
    <dbReference type="OrthoDB" id="1632785at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
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            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86146.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="218" mass="23714" checksum="E2E08B825E935581" modified="2007-12-04" version="1">MHIEPGILSAAKVVAANAAAIATLATYAPKLVRNPVILVKTVLAAAFFSVFMEIFHLPVGASELHFVGASAVYFIFGFVPTLFGFALGLLLQGALFEPQDLVHLGVNSLSLMVPLIAVHETFGKRFFARDESKLPVSWAQILKFDAAYYSGVVSMVGFWLLMGNEATPVYDWAIFAASYLPLVLCEPIFTFVALKLLGRIENNSAVRRFTVVGELATR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3279"/>
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        <property type="gene ID" value="AZC_3279"/>
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        <property type="entry name" value="ADH-like_C"/>
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        <property type="entry name" value="ADH_N"/>
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    </dbReference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="24"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="1">
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            <begin position="169"/>
            <end position="294"/>
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    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
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            <dbReference type="Pfam" id="PF08240"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89277.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="336" mass="36011" checksum="31F6D9EBF39EAB53" modified="2007-12-04" version="1">MKALLCEEPGRLSVISRPEPVPGPGEVLVRIRRVGICGTDFHIFQGKHPFLEYPRVMGHELSGTVEQAPEGSRLTRGENVYIVPYLSCGKCVACRKGVTNACQNIAVLGVHRDGGMAEFLCVPEQNVIPAGSASLDDAAMIEFLAIGAHGVKRGSITAQDKVLVVGAGPIGMSAIIFAKARGAEVSVMDTREDRLNFTRDALGANHLLIADAGAEDVARGITGGDFYDVVIDATGHAGAMQRGFGFVAHAGRYVLVSVVRQDITFSDPEFHKRETTLFASRNAQPDDFAEVVRQMEAGKVPTRALNTHRGALSDAPALFQEWLRPEAGVIKAILEV</sequence>
</entry>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <property type="entry name" value="SSF54001"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="177"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="302" mass="32438" checksum="6669ACC696CF30CD" modified="2007-12-04" version="1">MLYDIRQTTSYSYAGVVRATKQVVRMSPVDRQGHQHVIAHVLDVTPKPSELERGRDFFGNGIAWMVVDAAHDRLDISTRSRIEVSVAPLPEAETTPTVASIRLDAMASQDLGPASPVHGLYASRSIPLELTITEWAATSFPDERPVLAAALELMHRIHDDFAYQPGTTTVTTLPVEAFDARSGVCQDFAHVMIAGLRGVGLPARYVSGYLRTIPPEGQPRLAGADATHAWVEVWCGARIGWIGLDPTNAIPAGEDHVILAIGRDYADVSPVDGVVVSSGNQILAVGVDVIPVERPQADAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHT3</accession>
    <name>A8IHT3_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">PS_pyruv_trans domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3319"/>
    <dbReference type="EnsemblBacteria" id="BAF89317">
        <property type="protein sequence ID" value="BAF89317"/>
        <property type="gene ID" value="AZC_3319"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3319"/>
    <dbReference type="eggNOG" id="COG2327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037729_1_0_5"/>
    <dbReference type="OMA" id="CPSMYAF"/>
    <dbReference type="OrthoDB" id="540816at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="58"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="402" mass="46700" checksum="944E5AB300FD929F" modified="2007-12-04" version="1">MARVLVMIPSGEVYDHDCVRWYNYKDVQRSIDHYHNIGDAFVFDSSLKLMNFEKLGVLPIANPKMEDIDRLREEYDYVFLRGSNYVHNHMKWQNTIEVLKRLKLPVIAYGIGAQAPVKGEMELSEETKTVLHMMADSSASIGVRGAYSAQVLWDIGIRNIRIVGCPTAFRRNDPNLTITLPNLEDVKQVGITCRREVSPAYAQDIKRYLTFHRDLVKECANRWDVVLMAQGEVEEKKIVFGTAEQREEAIAALKANKWVSEWYWDDEIEKLHRERLFYSDVVADYEALVQQKDLVLGYRLHGNLMALSNGTPSIYFTYDSRTVEFAETYQIPSYDVFSKKEFKLEDYWDQGLFNKFNRAWAMTYREQKTFLDENGVDNKMVDTRHTPAPWSLGAEAPERKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHT6</accession>
    <name>A8IHT6_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">expE7</name>
        <name evidence="3" type="ordered locus">AZC_3320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3320"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF89318">
        <property type="protein sequence ID" value="BAF89318"/>
        <property type="gene ID" value="AZC_3320"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3320"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_35_1_5"/>
    <dbReference type="OMA" id="SIWWENS"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="42"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="264"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
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    <evidence type="ECO:0000259" key="2">
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            <dbReference type="Pfam" id="PF13439"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89318.1"/>
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    </evidence>
    <sequence length="462" mass="51616" checksum="79C8C8CF7419B1BB" modified="2007-12-04" version="1">MNAQPNPSAPLPAVPVPVAPDGSVEDLRVLIISHAHPGYSLGGAEVASHNLHKGLNAVGGASSRYLARVGNPVPRHGASALMSLRQKEDEILYHADDYDHFLLSNRNTEDLRRDFLRFVTDVQPHVVHFHHILGLGLETLFAVRDALPDTRIVVTFHEFLSICHHHGQMVKTAGMKLCQRSSPTDCHACFPDISPARFLQRERFVQSMLQLADHYVSPSHFLAQRFIDWGLDASRMSVIENGLDIAEVAPPRPLTGGNTRRGSFAYFGQMTPYKGADVLLDAVGRVPESVWSEDARMMIFGGNLERQPQAYQNKIAALVEKAGDRVRFYGSYQNVEMPRLMRSVDWMIMPSVWWENSPVVIQEAFHHGRPIISSNIGGMAEKIRDGVDGLHFRAGSAEDLADRLVEALTDDTLWERLRAGIRKPDTHLDFARTHLELYRRLRAEKRSDVPGATVQKAVARTA</sequence>
</entry>
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            <fullName evidence="1">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="1" type="ordered locus">AZC_3352</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89350.1"/>
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    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_3352"/>
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        <property type="gene ID" value="AZC_3352"/>
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    </dbReference>
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        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89350.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="240" mass="27005" checksum="C9160F7174CB9FD6" modified="2007-12-04" version="1">MSQGKTALVITAHPGDFVWRAGGAIALHARKGYRVKIACLSYGERGESQWAWKTAGVKLEDVKAQRKAEAEEAARILGAEIEFFDAGDYPLRGTEAILDRLIDIYREEKPAFVLTHSLNDPYNVDHPEATRLAQEARIIAQAAGHKPDPTRAYAAPPVFLFEPHQPEQCDFKPNVILNIDDVWEVKRKAFEVLAAQKHLWEYYTRVALNRGVQGGRNSGRAMTYGEAYQRLFPMILEELA</sequence>
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            <fullName evidence="3">von Willebrand factor type A domain protein</fullName>
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    <organism evidence="3 4">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
    <sequence length="343" mass="37132" checksum="3ECEE7F745FE54F9" modified="2007-12-04" version="1">MIQFQWLWAAALLPLPLLVRFLMPAAPKRRAGALRLPFFHEIAGAGLVSEGGRRRRLVRLALLSVIWLLLVGAAMRPAYVGKPVPIAVEGRDLMLAVDLSGSMSRQDLSYDNIPVDRLTIIKGVADDFIAKRKGDRIGLILFSTRAYVQAPLTFDRNVVRDLLRTSSIGMTGQETAIGDAIALAVKTLRTRPQEQRVLVLLTDGANNSGMLSPIPAAEIAKANGVKIYTIGVGADAFAVGQRMVNPSFDLDEGALEQIAQMTGGRYFRARDAAGLAAIYNDIDRMEPVSGEPLYLSPTVSLFQWPLGAALVLSFLLGLVWLWPARSRKAQAEAPAPNLEGAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIN3</accession>
    <name>A8IIN3_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3428</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171951.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3428"/>
    <dbReference type="EnsemblBacteria" id="BAF89426">
        <property type="protein sequence ID" value="BAF89426"/>
        <property type="gene ID" value="AZC_3428"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3428"/>
    <dbReference type="eggNOG" id="COG3209">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2244790_0_0_5"/>
    <dbReference type="OMA" id="DKMVYGE"/>
    <dbReference type="OrthoDB" id="1955727at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046154">
        <property type="entry name" value="DUF6156"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19653">
        <property type="entry name" value="DUF6156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="107" mass="11849" checksum="06B4AC7170071BA1" modified="2007-12-04" version="1">MIEEAETAQWPDQRFFVSYTGVKLPFTLVNPIAADALSNRNTFIRAYFDAAGVLRGFDKVVYGEIELSHRYAYHDNGALRHAAIVMLDEEPAELAFDAAGIPIASEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJJ5</accession>
    <name>A8IJJ5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NTP pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168846.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0315"/>
    <dbReference type="EnsemblBacteria" id="BAF86313">
        <property type="protein sequence ID" value="BAF86313"/>
        <property type="gene ID" value="AZC_0315"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0315"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_19_2_5"/>
    <dbReference type="OMA" id="HADQPGM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="134" mass="14903" checksum="AF92B319523616E8" modified="2007-12-04" version="1">MKITLVAACALVDADNRVLVAQRPEGKALAGLWEFPGGKVEPGERPEACLIRELHEELGITVKEACLAPLTFASHGYETFHLLMPLWICRRWEGQVIAREHKALKWLRAGKLRDIPMPPADEPLIPPLIDLLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK40</accession>
    <name>A8IK40_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0397</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Yamada M."/>
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                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="2 8">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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    </comment>
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    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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    </evidence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
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        <name evidence="16" type="ordered locus">AZC_4053</name>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell inner membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="1 2" key="4">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3" key="2">
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
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        <property type="protein sequence ID" value="BAF86529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0531"/>
    <dbReference type="EnsemblBacteria" id="BAF86529">
        <property type="protein sequence ID" value="BAF86529"/>
        <property type="gene ID" value="AZC_0531"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0531"/>
    <dbReference type="HOGENOM" id="CLU_1811831_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="142" mass="15183" checksum="C63E761D5F226B9B" modified="2007-12-04" version="1">MNQMAVAVRQGSTAAARRSDDSPHPRADSRQDRLPMDLSPALSPEDAFVADLVASGRYADAASVWREAIYLLAEREYERSVQETAQLSLLHDVLSREADGAPLVPDADGAETDLAFADADAVLSEIELLLSAGAPMAFRKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMG2</accession>
    <name>A8IMG2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane autotransporter barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0546</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0546"/>
    <dbReference type="EnsemblBacteria" id="BAF86544">
        <property type="protein sequence ID" value="BAF86544"/>
        <property type="gene ID" value="AZC_0546"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0546"/>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005887_4_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Autotransporter" evidence="1">
        <location>
            <begin position="870"/>
            <end position="1159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1159" mass="115337" checksum="4FBBAA3E1DF669FC" modified="2007-12-04" version="1">MSFASGGGKMAGRKDRASRARARIGRAVGTLAFLIAGTAIAGAQTFEAAGAIFFATASRQTSAIPLDLSTIIGSSAGIVSGSISSTGASGVGTVITSQAPIATGTMTPVTGFGTTIATAPTLIVAKPGSGSPQSPPAGWSLYSGYSTSYSIPYANTPVFGGPQAQLMVNVTVGGQTTQVQVDTGSQGIVIPQYLFGNQTFTGKQGTIVYSSSGNNATGIWTTMTVSFPGAKDQNGNPTTASASVPVFIEQSANNGTKDCTVAGTGCYFMMGIGYGRPDNGWTGYQPSLNTNPLLHLTGMDEGTVRSGYIVTATGIQAGLTAANAGQGYALIQLQPSTGQASANWTTPPGTLIVTPNGGSPATTALPVLVDTGISYLWGNLGTASTACTYHNQQFTCAPAGTAVTVYLGPGSYVGYSYVVGGSDNNSAAPPASRDSVIGALNTGISPLAQFDLMFDAVGGFAGYKATAPNTSGIYFSPYLSTAGALSVPDGFLTTLPVYVSSATTFSTTGTATLQGAVTGVSGLTVAGPGNTSFFGTVTLPSVTISGGAASFLANVTAPQFQVLSGAAAANSATLTATVSNAGTLINAGTIVGGVSNSGTVFNWQTVTGAVQSSGTFANTGTVNGTVTNSGTLTNDGTINGIVISTGTMNGNGIVTGALAVSGTVAPGHSIGTMAVNGNVELRRGSVYEAELGPAGTSDRILASGSATLDGTRIAVSPYAGYTPGLGSYQIITAGGGVSGTYSVSAPDFGALPAAYPFLAANGRITGSGLTIDMVRSTVPFAAAGITANETATGRGLDTLAQQGTLFNALLGLNAATAAGAYDQLSGEIYASTQSLLIDQSFYVRDGVLGRLRQESGAPGAAGAVQTATLVPGLPLTLWGEGYGGWGQAGGNGNSAGDSRSIGGFLMGLDLPLGTNWRAGIAGGYSQSTFSTDARGSSGTSDNYDVALYAGGALAAVGPGTLNLRAGAAYAWHDIAMSRSAAFSGFANALSAGYGADTAQVFAELGYGFTLEKTPLGRVGLEPFAGLAYVHLSTDGLTETFGAAALSVASSSFDTTLTQFGLRASAVLLPGPNLPAVDVHGLIGWQHAFGDTVPTVAASFASGSLPFTVSGAPIATDSLLLGFGLDTAIGQNARLGVAYTGQLASNVQDSAVKGTFSLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMR8</accession>
    <name>A8IMR8_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">Hydrogenase large subunit protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hupL</name>
        <name evidence="5" type="ordered locus">AZC_0599</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.</text>
    </comment>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="604" mass="66662" checksum="E143454A70BBD2CB" modified="2007-12-04" version="1">MTIQTPNGFSLDNAGRRIVVDPVTRIEGHMRCEVNVDANNVIRNAVSTGTMWRGLEVILKGRDPRDAWAFVERICGVCTGCHALTSVRAVEDALQIKIPNNAFLIREIMAKVLQWHDHVVHFYHLHALDWVNPVNALKADPKATSALQQSISNHSKSSPGYFRDVQNRLKTFVESGQLGIFKNGYWDNPAYKLPPEADLLAVTHYLEALDFQREIVKVHTIFGGKNPHPNYMVGGVPCAINMDGDMSAGAPLNMERLNFVKLKLQEALEFSANVYVPDVIAIASFYKDWLYGGGLSALNVMDYGDYEAIQGQKSTDRLPGGVILGGKWDEIHPIDPRDPAQVQEFVTHSWYTYGSGNNDKGLHPWDGVTEPKYELGPAAKGTKTNIEAVDEAAKYSWIKAPRWRGNAVEVGPLARYILAYSKGVDYVKGQVDEALGRFNTLAGTNFTPKQALPTTIGRTLARALEAHYCAVMMMDDFNHLIANIKAGDTSTANVEKWDPSTWPKEAKGVGTVAAPRGGLGHWIKIKDGRIENYQCVVPTTWNGGPRDPKGNIGAFEASLLNTPMQRPDEPVEILRTLHSFDPCLACSTHVLAPGGEELARVTVR</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172186.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3663"/>
    <dbReference type="EnsemblBacteria" id="BAF89661">
        <property type="protein sequence ID" value="BAF89661"/>
        <property type="gene ID" value="AZC_3663"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3663"/>
    <dbReference type="eggNOG" id="ENOG502Z9JE">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1110422_0_0_5"/>
    <dbReference type="OMA" id="MGWLEIT"/>
    <dbReference type="OrthoDB" id="868527at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="249" mass="27555" checksum="A51FB0DAAB9C13C3" modified="2007-12-04" version="1">MTDMAELQKRKLPINLSIVHVDPDAFLASFMGWLEITAFITAQRAGTAAVPADGVTPALSAQDLATPGVQAVANDALFAFCMTAALKGDVAAVDAVDAGLIARFGDDYPGKLAVGYFRAVNDNPILLEDFVGQAGRKWLKGDRPPPPLRAKEDWNAGLRFFEKARKSNFIHEVLYPLARWTRERWTVIVEKEPAFLHHIEDNLPILREALDDPRNDQAFIANLLLKAAPAVDMELTDEYEGFLRSLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMX3</accession>
    <name>A8IMX3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3673</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Sato S."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172196.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3673"/>
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        <property type="protein sequence ID" value="BAF89671"/>
        <property type="gene ID" value="AZC_3673"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3673"/>
    <dbReference type="eggNOG" id="COG4118">
        <property type="taxonomic scope" value="Bacteria"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <feature type="region of interest" description="Disordered" evidence="1">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <sequence length="397" mass="44030" checksum="0C4B8F30E06B89D0" modified="2007-12-04" version="1">MNMKVLGAGRDASGGYKVDVTRGERVGRVSSEWFSRPDDERFLSLGELAAMVLGRADHSRSRLVETSRIHVEASRSNAERLALVLPGADAPVEPNHWSFGQLAAQIGAPAAYLRQLPAALAGINLQYGLTAHRAEQIKTFETDNGRVELRAVTGPDYGRIYDHELVEAVQRIAGNGTGDTRWKVPGVLDWSTGVYNPCVNITKDTTTLYASDRDVFLFLVDDLNPIEAGRLPDGSPDLYFRGFYCWNSEVGAKTLGIASFYLRAVCQNRNLWGVEDFQEITIRHSKYAASRFAHEAAPALTRFANSSPMPFVNGIKAAREKIVARTDEDRSDFLRNRGFSRVETARIIDTVLAEEGRKPESIFDFVQGITAFARDKPHQDARLDLEGRAKKLLDRAA</sequence>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
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            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169222.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0691"/>
    <dbReference type="EnsemblBacteria" id="BAF86689">
        <property type="protein sequence ID" value="BAF86689"/>
        <property type="gene ID" value="AZC_0691"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0691"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037398_0_1_5"/>
    <dbReference type="OMA" id="CEDPANH"/>
    <dbReference type="OrthoDB" id="1832232at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="378" mass="40624" checksum="E1158E97C81F54D6" modified="2007-12-04" version="1">MKRLSIGFIPLTDAAVLIAAAERGFAMAEGIEIELHKEVSWANIRDKVNVGLLDGAHMLGPLAIASSLGLGHVRVPLVVPFALNLNGSAITIAKSVYAAMGETGGDLTSALGAAQALGKVVIDRRERGEDPLTFAAVYTFSTHHYLIRHFLTAGGIDPDRDVRLVVIPPPFMAESLRNGLIHGFSVGSPWNSVAVDADVGRIAVLGAEIFGWVPEKVLGVHARFANAEPEVLHRLVRALNAAAAWCEDPANHADLARLLSEPRHLSLPADILRRTLDGRLHTAPGGVLRSHPDYLVLHREGANRPDPDHALWMYHQIVAAHQGDWAPDAAREAISVYRPDIFDAAVGAAPPSPPREPDCVATQFGPVFDKERFLATGE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPW5</accession>
    <name>DUT_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="1">dUTPase</shortName>
            <ecNumber evidence="1">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dut</name>
        <name type="ordered locus">AZC_0707</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dUTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169238.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IPW5"/>
    <dbReference type="SMR" id="A8IPW5"/>
    <dbReference type="STRING" id="438753.AZC_0707"/>
    <dbReference type="EnsemblBacteria" id="BAF86705">
        <property type="protein sequence ID" value="BAF86705"/>
        <property type="gene ID" value="AZC_0707"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0707"/>
    <dbReference type="eggNOG" id="COG0756">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068508_1_2_5"/>
    <dbReference type="OMA" id="YAAFVHP"/>
    <dbReference type="OrthoDB" id="1669228at2"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0546">Nucleotide metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071353" description="Deoxyuridine 5'-triphosphate nucleotidohydrolase">
        <location>
            <begin position="1"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="90"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <sequence length="157" mass="16233" checksum="AEEBECA2C60396F6" modified="2007-12-04" version="1">MSATRLDVPVVRLPHGMDLPLPEYATAASAGMDLVAAVPAEVPLVIAPGAWALVPTGLALELPEGMEAQVRPRSGLALKFGVTVLNAPGTIDADYRGEVGVILINHGREPFTVSRGMRIAQMVIAGVQQITLVETGNLGETARGVGGFGSTGLDRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQH6</accession>
    <name>A8IQH6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_0784</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0784"/>
    <dbReference type="EnsemblBacteria" id="BAF86782">
        <property type="protein sequence ID" value="BAF86782"/>
        <property type="gene ID" value="AZC_0784"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0784"/>
    <dbReference type="eggNOG" id="COG1177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_3_4_5"/>
    <dbReference type="OMA" id="FRRSWLF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="65"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="267" mass="28662" checksum="BEBC3D33B4CFED96" modified="2007-12-04" version="1">MRPMKRSPLVFALQLVITLLATAFLVVPAGTSILAGVTVNYFQGVRSGLTLEWVAQVWGLYAPTIFRSIALALGTLVVTLALGVPSAWALARKPGRMSRLVEEVVTLPVAIPGLALALALIIAYGGIREFRASILFILVGHVLYTLPFMLRSVMAVLAAVDVRTLEEGAASLGATPWQRFIQVVVPNARGGIIAGSLMVVTLSIGEFNLTWMLHTPLTQTLPVGLADSYASMRLEIASAYTLVFFIMIVPLLVAIQLLGGERRAAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQI5</accession>
    <name>A8IQI5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0787</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0787"/>
    <dbReference type="EnsemblBacteria" id="BAF86785">
        <property type="protein sequence ID" value="BAF86785"/>
        <property type="gene ID" value="AZC_0787"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0787"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024588_6_0_5"/>
    <dbReference type="OMA" id="WTLDTDS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="5">
        <location>
            <begin position="220"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>allantoate</name>
            <dbReference type="ChEBI" id="CHEBI:17536"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="418" mass="42993" checksum="CE26DE2FBC28490C" modified="2007-12-04" version="1">MMSVATESSATDVLEGSRLLARLEALARFTDVPGEMTRLTLSPAHKAAAAEVARWFAAAGMAVHLDATGSVVGRYEGTQPDAPALILGSHIDTVRNAGIFDGNLGVVVALAVVEQLHADGVRLPFALEVHAFADEEGVRFPSTLTSSRALAGRFDAAALDATDADGITRREALKAFGVDPEAYAACSRAGRALGYVEVHIEQGPVLEAKGLPVGIVTAIAGATRGTIELVGEAGHSGTLPMEMRHDALAGAADMILALERLAKATPGLVATVGTLTIPGGAVNVVPGRVRFSFDVRAPDDRTRLDALDTMRATLAEIAAARGLATTLEETYDAPAAPCDGALQAALAAAVAAEGIDALHLPSGAGHDGLSLNGVMPIAMLFVRSRNGSHNPREHASAEDIGAAARVLSRFVRGYTPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRM4</accession>
    <name>A8HRM4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sbcD</name>
        <name evidence="2" type="ordered locus">AZC_1212</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF87210">
        <property type="protein sequence ID" value="BAF87210"/>
        <property type="gene ID" value="AZC_1212"/>
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    <evidence type="ECO:0000313" key="3">
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    <sequence length="373" mass="40418" checksum="898D0C352D749942" modified="2007-12-04" version="1">MRLIHSADWQLGKPFGRMPVDARAALSEARLDAIDTLAAAARQHRAGHVLVAGDVFDSAEPGDRIYRQALARMKAAAGVRWWLLPGNHDPLRPDGLWSRLSAEAPENVAACLTPAPVMLGEDAVLLPAPLTHKFSLSDPTAWFDGAETPAGLPRIGLAHGAIRTFGGDEQTNLIAPDRARRAGLSYLALGDWHGLRKIDGHTYYSGTPEPDDFGREATGLALLVDVAGAGLEPQVEALPIGRHAWVEERWHLSGAEDVAPRIAALAPGIERKHLVARLHLSGLVPLAERVTLRRLLEDGLAHEIRWLDLDLADLMTRPTETDLSEIDAHGELRDAAERLRAMAEDGGTEGRLAGAALERLYVELMRAQRGSEA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <comment type="cofactor">
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            <name>pyridoxal 5'-phosphate</name>
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        </cofactor>
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    <comment type="similarity">
        <text evidence="2">Belongs to the alanine racemase family.</text>
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        <property type="protein sequence ID" value="BAF90214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_4216"/>
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        <property type="entry name" value="PLP-binding_barrel"/>
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        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <ligand>
            <name>substrate</name>
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    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="374" mass="39894" checksum="ED7E1EB666F636B4" modified="2007-12-04" version="1">MPEPTADLATLEIDLGAVRQNWRTVRAQYRGPTLGAVVKQNAYGFGLSRIVPLLSSLGCRDFWVVCIEEALAVRTLAPDARVFVLHGLAGAAPADFRAHRIIPVLMDASELPRVQAEAAARGPLDVAIQFDTGLSRLGLSRTDVKRLRDDPSPLAGLRIAAYVTHLAHFSNPVARHNDWQWRRFRAWTQALPPAPLSFCASAGVFGPPERHAHHARVGSALYGVETTPSSRQPILPAARLTAPILRVMDVPAGTEVGYGGVYRTPQPARLAHVGVGYGGGLPFSFQRQAYGYVGGLPAPIVSGLAMSLMTLDVSGLPEGLAVPGAQVELFGPAQPVDILAAAAGVAPNVVMVSAGARTRRVYLEPSEEKLRVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSW9</accession>
    <name>A8HSW9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitrogen regulatory protein P-II</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glnK</name>
        <name evidence="8" type="ordered locus">AZC_4227</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP. P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme. Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS. P-II indirectly controls the transcription of the GS gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the P(II) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172747.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4227"/>
    <dbReference type="EnsemblBacteria" id="BAF90225">
        <property type="protein sequence ID" value="BAF90225"/>
        <property type="gene ID" value="AZC_4227"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4227"/>
    <dbReference type="eggNOG" id="COG0347">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082268_0_0_5"/>
    <dbReference type="OMA" id="LEMAIHT"/>
    <dbReference type="OrthoDB" id="2021322at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017918">
        <property type="entry name" value="N-reg_PII_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002332">
        <property type="entry name" value="N-reg_PII_urydylation_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039144">
        <property type="entry name" value="GlnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00638">
        <property type="entry name" value="PII_GLNB_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00496">
        <property type="entry name" value="PII_GLNB_UMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR039144-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="112" mass="12123" checksum="DBB1FFDA8C85AAED" modified="2007-12-04" version="1">MKIVMAIIKPFKLEEVRDALTGIGVHGLTVTEVKGYGRQKGHTEIYRGAEYAVSFLPKLKIEVAVPSDQVAKVVEAITASAKTGQIGDGKIFVFQIDHAVRIRTGETDADAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT09</accession>
    <name>A8HT09_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4241</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF90239">
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    <dbReference type="eggNOG" id="ENOG5031PVX">
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="34"/>
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            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="188"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="239" mass="25985" checksum="12AD458468AF85A8" modified="2007-12-04" version="1">MDRKHGKGPMRNTMRRSLQTSRMRAFLLAASALAATPALFAAAPAAAQTANQLPQSQDGTLMNSIMGAIGIGGDTRPSIDYRERAPLVVPPSAANGELPQPQAPASTKLNNWPKDPDMARAEKANAVDNSPAQRYEDKRDVLLPSELNKGRKANAGKLDGPAQRYEDKRDVLSPSELGFKSWFGITPSDQKPMVFTGEPTRESLTQPPTGYQTPAPNAPYGVVEKKNEPFKFPTLFDRN</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0828"/>
    <dbReference type="EnsemblBacteria" id="BAF86826">
        <property type="protein sequence ID" value="BAF86826"/>
        <property type="gene ID" value="AZC_0828"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0828"/>
    <dbReference type="eggNOG" id="COG4974">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027562_17_7_5"/>
    <dbReference type="OMA" id="TWWGRVQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CB"/>
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    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
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    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0229">DNA integration</keyword>
    <keyword evidence="3" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="73"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="6">
        <location>
            <begin position="183"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="359"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="384" mass="43185" checksum="2D02E1466AA25BA9" modified="2007-12-04" version="1">MDLRRSRASQLDQGAHNMPPKPKAPKHTYWRGDTLWARFTVAGREIRESLRTGSAKVAARRVAEMREKAVGATRFGETRVLWDDAVTAWASFIPRQVGSPRTVKRYADSLSIAGRHFSTLPIADIDKDAINRFVAARRAEGVTNATIRRDLQAISSLLDFSEDEGWRDGNPALDKMRRLKEHRDPIMLPDDGDYAFVLSRLQEGHAEMLRAARATGMRQDELARAERRHFNAANSSLLVRGKGNKQRTISLSAEAAAIFSRQPVSLACPHIFHHAGKPITKAAFIFSRARRAAQKAAQKAGMEFRGFRFHDMRHLYAVEFLRSGGDIYTLKEHLRHSSVKTTEMYLEFLTPEEAELAKRGRKAGLDGQGGLMEEGRRASKGREV</sequence>
</entry>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <sequence length="350" mass="35449" checksum="B49B3AD4AFD130F4" modified="2007-12-04" version="1">MGFWKWSKTPAANAAIDPPINWAEGQLASTVNDSARAMMAALAAYRDDNGGALAATVATADGNGHATAYAVTTNQGLTSGSVPNGFTLTVSAAATNAAAATLTVDGQAGPIMADGFSVPFGALRKGSRFSVSWDDPWWRLVHPLGAVVGDEKVVFSPSAPSGWLAANGLYIGPTGSVADGFAGPEAFDLFVYLWPRTVLTVTGGRGASALADWTANKALALPDMRGAVWVGRDSMGSFDTGRLISGAFPSGRDTVGTSGGAAQITLGIGQIPAHKHNVSLSAAPDHTHSYTRPQAGAGTVLATGTNAGGTADVTGPAGGHTHPVTEDTVGGGGAHDNIQYSSIRTFCIKL</sequence>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="5 6" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="ChEBI" id="CHEBI:58210"/>
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        <text evidence="3">Binds 1 FMN per subunit.</text>
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        <text evidence="1 2">Belongs to the nitroreductase family.</text>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000232-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="187" mass="20584" checksum="08F878C56690B96C" modified="2007-12-04" version="1">MPDALDLLRTRRSSRIVDLTGPAPKPEELDTILSIAARVPDHGKLAPWRFIVFEGEGRLRAGEALAKVFAELNPDATEKRLEDEKGRFARVPLVVAVVSSAQPHVKIPEWEQLLSSAAAAQNLLLATLALGYGATWITEWPTYEPKARAALGLAEHERITGFIYIGTPTQALEDRPRPALSEVVTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVA7</accession>
    <name>A8HVA7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Heavy metal translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_4294</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4294"/>
    <dbReference type="EnsemblBacteria" id="BAF90292">
        <property type="protein sequence ID" value="BAF90292"/>
        <property type="gene ID" value="AZC_4294"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4294"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_11_3_5"/>
    <dbReference type="OMA" id="KARVHYD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007029">
        <property type="entry name" value="YHS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04945">
        <property type="entry name" value="YHS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="517"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="545"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="860"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="888"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="7">
        <location>
            <begin position="78"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="TRASH" evidence="7">
        <location>
            <begin position="160"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="915" mass="94408" checksum="24DAB1BA606EC099" modified="2007-12-04" version="1">MAHEHHTHGSNADAGSCCGGKAPAPLDLAPKAASPAAGDCCGGAAPPPLVLPATGAPEADCCGGNAPPPLDLSPKAIDPVCGMSVDIATAKHRATYQGKTFYFCCNGCKTKFEADPEAQLAKAKARDEAKAAQKTEASACCGHDHGHAHHAPASGALVKDPVCGMDVDPATAKYKSHHGGHDVFFCSPSCKTKFDAHPEHYTDGGAPPPVDVPEGTIFTCPMDPEIRQIGPGTCPICGMALEPEVASLDDGPNVELIDMTRRFWIGLALALPVFVLEMGSHLGLHLIAPQVSNYVQFALASPVVLWAGWPFFQRGVASVRSGHLNMFTLIALGTGVAYLYSLAGTFLPGLFPNAFRGHGGAVPVYFEAAAVITVLVLLGQVLELRARAATSGAIKALLGLAPKTARRIAADGSEADVAIEEIHPGDLLRLRPGEKVPVDGTVEEGRASVDESLVTGESLPVTKETGATAIAGTLVASGGFVMRATKVGRETLLAQIVQMVAQAQRSRAPIQRLADQVSGWFVPAVLAAALASFAVWMWVGPEPRLTFALMAAVSVVIIACPCALGLATPMSIMVGVGRGAQAGILIKSAEALERMEKVTVLVVDKTGTLTQGKPKVTGIRATGLPEDELLRLAASLEQASEHPLAAAVVAEAQARGLKLAPVADFDSPAGKGVSGTVEGRRLLIGNADYLRDSGVPTDAQVKEAEALRAEGATVVLVAVDGTAAGLIAIADPVKATTPDALKALKAEGVRVVMLTGDTRTTAEAVARRLGITEVEAGVLPDRKADVVQRLRAEGEVVAMAGDGVNDAPALAAADVGIAMGTGTDVAMESAGITLLKGDLAGLAQARSLSRATMRNIRRSLFFAFVYNAAGVPLAAGILYPVLGLLLSPMVAAAAMSLSSVSVIANALLLRRWRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVB2</accession>
    <name>A8HVB2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">grxC</name>
        <name evidence="4" type="ordered locus">AZC_4296</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="1 2">Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutaredoxin family.</text>
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        <property type="protein sequence ID" value="BAF90294.1"/>
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        <property type="entry name" value="Glutaredoxin"/>
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        <property type="entry name" value="Glutaredoxin_subgr"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="3">
        <location>
            <begin position="4"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002549"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90294.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    <sequence length="85" mass="9327" checksum="B4EEA9AAE2D96A8E" modified="2007-12-04" version="1">MKSIVIYTKSWCSYCHAAKELLRRKGWTFTEIDVTTDPAGQQEMSKKAGGRTSVPQIFIGDTHVGGCDDLYALEDAGRLDALMAA</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF90426">
        <property type="protein sequence ID" value="BAF90426"/>
        <property type="gene ID" value="AZC_4428"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4428"/>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="CVGWLHE"/>
    <dbReference type="OrthoDB" id="1698673at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="AB_hydrolase"/>
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        <property type="entry name" value="SSF53474"/>
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    <proteinExistence type="predicted"/>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="585" mass="63263" checksum="B34845B25B316DC5" modified="2007-12-04" version="1">MLPISFDGCAGWLHLPAEGRARGRGVIICESFGYEALSTQRATLVLARTCAEAGLPTLSFHYPGTGDSAGEETPGQIERWIASIGAAAAFLKAQTGLEDIALCGLRLGGLLAIEAAQTFGGISALALLAPVLSGKTYARELLLSGSMVPSREGSLPPGWREFLGYRLHNDDLARLRILDGEARLGSLSHVRVRIASPAARPAALPADIAWGPFQHHDGLAQHAQDLMLPLCAFRETAAWLAEGAAGAAVPPVPPAREALEVAPGLQELVLRLGPGGRALGILTRPAHVKADWGAVILNSGLNHHTGNGRSGVRLARRLAAQGVPTLRLDLDKIGDCAPADPDETVGFHDLGRVEDVRAAVDQLVQQGSSRVLLTGICAGAYIGLHAAANDPRIRAAVLVNLPYFYIRDEDPAIPLWRRPLRLAVRLADRTRRWRAALLWNRNPEFGPAFFRRRYVTQRVLLLWHYALLSVSCRLKGTLRRFLPALQPGARARRLLQALVAHGTALTLVYGTQDWGLVELGILFPDHQRDLVDAGYADLRFIENADHTLTNAWMFDAYARILEEMLGLPPEAPEAGSRQASEEHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWH8</accession>
    <name>A8HWH8_AZOC5</name>
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        <submittedName>
            <fullName evidence="10">Putative TonB-dependent receptor</fullName>
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    <gene>
        <name evidence="10" type="ordered locus">AZC_4433</name>
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    <organism evidence="10 11">
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="BAF90431">
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    </evidence>
    <evidence type="ECO:0000313" key="11">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="protein sequence ID" value="BAF87487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="MFS"/>
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    <dbReference type="Pfam" id="PF07690">
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        <property type="match status" value="1"/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Akiba N."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
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                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="1 2" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <sequence length="590" mass="66609" checksum="C49C18E4A187F993" modified="2007-12-04" version="1">MRGEWHMSMELHVFFRGALPARAAVNAMFRELTFPVSLSGRGTLEGHRGFLPMKLRREETGVEFDVFDDQEMIAQFAGEVDPGFDRSASFRWGGDEDEMLAALCTAAALAKLLGAVVLDEEEDRPFPADRAVEMARRSLDVVQARRDAEKAKGRVPGTRPADIKRYVKPLLALRPDLTVADRALVIRPVRHVLRGAFFDRTGDPYSFSVSRILVPLYDAHFDIFLRDRVRGAGRDVWEQHFQMLLLDHLAEHVFAPAGQVRTLSAVAERLAGTFRRQGGDNALFKAPVRAFILAGAPERAEAYLDDLARDNADRPHMLRAIQELRSELDRDIAELCAEAHAREAEMVVALKLQSVWEPSPFPVEEPKASHARRCDEAPFSIRPWVQTPEGLFADEPVETNTPSFSHGRLVRAGRNMLLLPLTREEAERRHHAREDYLLTVRPMEKGRLTVHYLGKRPKSPHDPRDPDFLPPLSIWLSLDVPGWHVKARLYGDLDRQGWLGDLNVEISPQGSSQEAWCAGLRSRPSAWEITDRREGEPARRTEIPMTEAEMAPYLEATFAFGDYWALLHHVDAFTRMAGYGPLPGLPERPA</sequence>
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                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="285" mass="30390" checksum="6E2FD1559FCF7A32" modified="2007-12-04" version="1">MTDAAKTPSLADLRAEIDRIDETMHRLLMERSEIIDRLVQVKRTQTEGSAFRPAREASMMRSLVERHHGLLPLDTVESIWRVIIATFTYVQAPYSVHADLSVGEPLMRDSARFHFGFTAPFVPHMGARAVVEAVAASRGDLGLLPAAMVPGSDAWWTALEGVTAPKIIARLPFVERADHPAGLPVFVVSHPIADAAVTEVSTFSVRVAGWSARAAAAVATHAEVLAVADGALDGAALLVSVRGTDGGTVQDVLRQSGASVRSFIPVGSHAAPYRFGMDSAGIARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0I2</accession>
    <name>A8I0I2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ordered locus">AZC_1261</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169792.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1261"/>
    <dbReference type="EnsemblBacteria" id="BAF87259">
        <property type="protein sequence ID" value="BAF87259"/>
        <property type="gene ID" value="AZC_1261"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1261"/>
    <dbReference type="eggNOG" id="COG0112">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022477_2_1_5"/>
    <dbReference type="OMA" id="GRRYYEG"/>
    <dbReference type="OrthoDB" id="861782at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="23"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="140"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="437" mass="46563" checksum="B46FA95C2C2497A5" modified="2007-12-04" version="1">MASSAAHSASASAEMNRFFSASLAEVDPEIAAAVSAELGRQREEIELIASENIVSRAVLEAQGSVLTNKYAEGYPGKRYYGGCQFVDVAENLAIDRAKKLFGCAFANVQPNSGSQANQGVFFTLMQPGDTFLGLNLAAGGHLTHGSPVNMSGKWFNAVAYGVREDDQRIDYDVVAQLADQHKPKVIVAGGSAYPRVIDFARMRQIADSVGAKLMVDMAHFAGLVAGGAHPSPFPHAHVVTTTTHKTLRGPRGGMILTNDEELAKKLNSAIFPGIQGGPLMHVIAAKAVAFGEALRPEFKVYAKNVVENARALAENLRGHGFDIVSDGTDTHLMLVDLRPKRLTGKISENALGRAHITCNKNGIPFDPEKPAVTSGVRLGTPAGTTRGFGVAEFQQIGDMIAEVLDVLSQKGVAEDSLVEEAVRGKVKSLLARFPIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0L0</accession>
    <name>A8I0L0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10684"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="EC" id="3.1.3.48"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169801.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1270"/>
    <dbReference type="EnsemblBacteria" id="BAF87268">
        <property type="protein sequence ID" value="BAF87268"/>
        <property type="gene ID" value="AZC_1270"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1270"/>
    <dbReference type="eggNOG" id="COG0394">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071415_3_0_5"/>
    <dbReference type="OMA" id="KPITAHW"/>
    <dbReference type="OrthoDB" id="1800563at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="4">
        <location>
            <begin position="6"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="180" mass="19930" checksum="4129A17D7F79FC4D" modified="2007-12-04" version="1">MTDHTYNVLFLCTGNSARSILGEAMLNKLGEGRFRAFSAGSKPKGEVNPLAIEVLREADFPTDGLSSKSWEVFARADTPTMDFIFTVCDDAAGETCPIWPGHPATAHWGIEDPAAVEGTYLERRKAFVRAQRYLLNRISAFMALPLRSLDRMALHNQLRAIGQLTDAYVARSNLLHSESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1B1</accession>
    <name>A8I1B1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Cytochrome BD2 subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">AZC_1354</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169882.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1354"/>
    <dbReference type="EnsemblBacteria" id="BAF87352">
        <property type="protein sequence ID" value="BAF87352"/>
        <property type="gene ID" value="AZC_1354"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1354"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_1_5"/>
    <dbReference type="OMA" id="WPDSENE"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF87352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="470" mass="51527" checksum="4B0A96D583853E2B" modified="2007-12-04" version="1">MELTPLLLSRIQFAFTISFHIIFPAFTIGLAAWLTFLEACHLFTGERIYRRLSDFWLKIFAVAFGLGVVSGIVMAFQFGTNWSELSRRTGPIQGPLLGYESFTAFALEAAFFGVLMFGRDRVPRWAYLGACLMVSLGTSLSAFWIMVNNSWMQYPTGFSLTPDGVFVPTDWSAIIFNQAVWTRFPHMIIAAYVTSAFCVAATGAWYMLRGTAVQEGRAMAVMGLRLAAILVPVQLGFGHLVGDFVHDKQPAKFAAIEGRWNDQQPASEILVAWPDSENERNLFEISVPYLGSVIGSMSLTSKELGIKSFAPQDRPPVAIPFFAFRIMVGCGLVMLALAWIGSWLSFSERLLKARLFLVATFLSFPLGFIATLTGWFTAEVGRQPWVVYGQLRTAEAATPFLTSQEVATTFALVAAVYALIFGFGVLYIYRLLRAGPIPAAALSLYGTNPKRPLSIPGASPGVSGAAKTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1B7</accession>
    <name>A8I1B7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Formate dehydrogenase alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1356</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1356"/>
    <dbReference type="EnsemblBacteria" id="BAF87354">
        <property type="protein sequence ID" value="BAF87354"/>
        <property type="gene ID" value="AZC_1356"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1356"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_16_1_5"/>
    <dbReference type="OMA" id="PRSLKCH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02787">
        <property type="entry name" value="MopB_CT_ydeP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02767">
        <property type="entry name" value="MopB_ydeP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037951">
        <property type="entry name" value="MopB_CT_YdeP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010046">
        <property type="entry name" value="Mopterin_OxRdtse_a_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041953">
        <property type="entry name" value="YdeP_MopB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43105:SF4">
        <property type="entry name" value="PTHR43105:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01701">
        <property type="entry name" value="Fdhalpha-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin" evidence="5">
        <location>
            <begin position="110"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="6">
        <location>
            <begin position="645"/>
            <end position="753"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="766" mass="83766" checksum="045C61F2FC5E8F5D" modified="2007-12-04" version="1">MGVAKTIRPYHQPAGGWGALKAMGTALVEQHVAVHGMATLARMNQPGGFDCPGCGWADPKHTSPFEYCENGGKAVAWEMTTRRCTPAFFESHTVSELSALNDYELEMEGRLTHPMRYDAISDRYLPVSWDEAFALVGAHLNALPDPNMAEFYTSGRASNEAAFLYQLFAREYGTNNFPDCSNMCHEATSVGLPQSIGVGKGTVLLEDFARADCIFIFGQNPGTNSPRMMTELRNASRRGATIMSFNPFRERALERFQAPQSPVEMATLSSTPISSRLYQVKVGGDVALIKGLMKCLLAADEEARARESAPVLDWDFIKGHTAGIEALVADLNATSWSDVERKSGISRTEIEIAAQAYMKAERAILVYGMGITQHRHGTQNVQQIANLALLRGNVGREGAGICPVRGHSNVQGDRTVGITETPSRALLDAIEARYGFSPPKADGHNVVTALEAMVRGETKVFIGLGGNFAAAIPDWQLTQQAMRGLDLTVHIATKLNRSHLVHGRDALILPCLGRTEIDMQASGPQSVTVEDSMSMVHASTGHNLPASENLKSEPAIIAGMARATLGHRSKVNWEALTEDYARIREEIEAVFPIFQGYNARIREPGGFHLTSLARERIWATATGKANFLVCDGLCEDPQVSEKDVLWLTTVRSHDQYNTTLYSLSDRYRGVYGQRDVIFLSQAEMDRRGLKADDRVDIVTVSQDGVERAVRAFRVVPYAFPEGGCAAYYPETNPLVPLYAHDPQSFTPASKGVPVRLVKSTATPAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I234</accession>
    <name>A8I234_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative sodium/sulphate symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170371.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1843"/>
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        <property type="protein sequence ID" value="BAF87841"/>
        <property type="gene ID" value="AZC_1843"/>
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        <source>
            <dbReference type="EMBL" id="BAF87841.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="227" mass="24346" checksum="F0994C4D3123F720" modified="2007-12-04" version="1">MSRPVRTSLSVIEDALGPLEGKHVLDLGCGHGALAKALVRRGAEVTGVDPQIEAVEAAEQAVPEARFVQAGAEHLPHRDGLFDAVVILNALHHVPAPLMRAALREAVRVSAGPVLVIEPLAEGSFFEAVRLVDDETEIRALAQAALTDAIAAGDVTLVRMEEYEDHRAFSGPEALLRKIVEVDPARAEIAARRAPEVVEVVRAVAEPQGEGFVLIQPHRAHLLRRPS</sequence>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="entry name" value="L33_sf"/>
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    <dbReference type="PROSITE" id="PS00582">
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    <keyword id="KW-0689">Ribosomal protein</keyword>
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            <begin position="1"/>
            <end position="55"/>
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    </feature>
    <evidence type="ECO:0000255" key="1">
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    </evidence>
    <sequence length="55" mass="6297" checksum="ED8B433E947943E0" modified="2007-12-04" version="1">MAKAATIKIKLLSSADTGVFYVTKKNSRTKTDKIVLKKYDPVARKHVEFRETKIK</sequence>
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    <accession>A8I2E5</accession>
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        <recommendedName>
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        <alternativeName>
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        <name evidence="10" type="primary">topA</name>
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    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170389.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1861"/>
    <dbReference type="EnsemblBacteria" id="BAF87859">
        <property type="protein sequence ID" value="BAF87859"/>
        <property type="gene ID" value="AZC_1861"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1861"/>
    <dbReference type="eggNOG" id="COG0550">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1754">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002929_0_2_5"/>
    <dbReference type="OMA" id="PECKYTR"/>
    <dbReference type="OrthoDB" id="223233at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025589">
        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13368">
        <property type="entry name" value="Toprim_C_rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="12">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="165"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="767"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="834"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF87859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="892" mass="96988" checksum="46F929E34DC92532" modified="2007-12-04" version="1">MQVVIVESPAKAKTINKYLGPGYEVIASYGHIRDLPSKDGSVDPEADFRMLWEVDPKAQKRLNDIAKAVKVADGLILATDPDREGEAISWHVLEVLREKKALKGQKVERVVFNAITKQAVLEAMKAPRAVDVALVDAYLARRALDYLVGFTLSPVLWRKLPGARSAGRVQSVALRLVCDREREIELFVAKEYWSIAATLATPRGDTFEARLSGADGKKITRLSVGTAEEAAAFRAALDTAAFSVRNVEAKPVRRHPQPPFTTSTLQQEASRKLGLAPARTMQIAQRLYEGVDIGGETAGLITYMRTDGVDMAPEAVTATRNAISAQYGARYLPGTPRKYTTKAKNAQEAHEAIRPTDPSRHPREMARHLDAEQARLYELIWTRTIASQMESAELERTTADIIAKAAGRELELTATGTVVKFDGFLTLYREGKDDEDDDEESRRLPAMSAGEALDKREIKTDQHFTEPPPRYSEASLVKRMEELGIGRPSTYAAVLAVLRDREYVKLEKKRLVPEDKGRLVTAFLQSFFKKYVEYDFTADLEEKLDEISAAEIDWKQVLRDFWNDFSLAVDATKELRVSQVIDALDEILTAHLFPAKEDGSDPRLCPTCGSGRLSLKMGKFGAFIGCSNYPECRYTRPLSGGEGEAGGDGVRKLGTDPETGLEVTLRDGRFGAYLQLGEAVDGEKPKRSSLPKGLAPADVDLETALALLALPRRVGTHPEDGEPILAGIGRFGPYIQHGKVYANLEAADDVLTVGLNRAVVLLAEKQSRGRGGRGAAPAGRTLGDHPTEGGAITVRAGRFGPYVNHGKINATLPKSQDPDSLTLEQALALIEAKAAASPSARKPARKSASADGAAKKAPAKKTATKTAAKKTTTKAAGTKKTAKAKADAAAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2K9</accession>
    <name>A8I2K9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1893</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170421.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1893"/>
    <dbReference type="EnsemblBacteria" id="BAF87891">
        <property type="protein sequence ID" value="BAF87891"/>
        <property type="gene ID" value="AZC_1893"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1893"/>
    <dbReference type="eggNOG" id="COG1359">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131496_3_2_5"/>
    <dbReference type="OMA" id="TAHFRDS"/>
    <dbReference type="OrthoDB" id="1909149at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="106" mass="11466" checksum="EB88C7DE15FA1380" modified="2007-12-04" version="1">MSVPSPFVVIAEFQVKPGRLADFLALAHDDATSSVSSEPGCRTFDVCVSAAEADTVVFYEVYDDRAAFDAHLETPHFARFRDGFPALIVAERPVRFLARATSGAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2Z5</accession>
    <name>A8I2Z5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170487.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1960"/>
    <dbReference type="EnsemblBacteria" id="BAF87958">
        <property type="protein sequence ID" value="BAF87958"/>
        <property type="gene ID" value="AZC_1960"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1960"/>
    <dbReference type="eggNOG" id="COG2072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044076_0_0_5"/>
    <dbReference type="OMA" id="NPYRWME"/>
    <dbReference type="OrthoDB" id="324612at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="477" mass="53354" checksum="9D0EC723543755BA" modified="2007-12-04" version="1">MTTTFGSTDGLRALEQQVRDDLARIAHPKAPWVKPRTAPGGKPAYDVVIVGGGQCGLGTAFCLQRSKVDNILVLDQAPRDLEGPWRTYSRMLTLRSPKDFTGPDMDIPSLTYQAWHEARYGKEAWTELKLIPKDLWADYLLWYRDVLDLPVRNLCQVTDIGPADGLLALTVNTPDGVETIYARKVVLATGQEGMGNWTLPAELERLPEHLRARSSDMIDFDALKGKTVIVIGAGASAFDNAATALEAGVGEVMQLCRRFEPQLVQPYLWFTFRGFMRHLSELTDEWRWRFMSRALRLREAFPQATYDRCARHANFHLTTGAGLIDAYEQDGRAVVSTQAGTFTADYVIACTGIGMDFGARPELKRFAHNIATWGDRYTPPDHEKEARLSQFPYLAEDYAFEEKTAGETPWVSDIHLFSIASTMSFGASGSSINAMTTAIPKLVHGLTRDLFQDDLDQFWADFQAYDVPQAVVRKLEA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4D4</accession>
    <name>GLMU_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="1">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="1">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="1">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">glmU</name>
        <name type="ordered locus">AZC_1718</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="1"/>
    <dbReference type="EC" id="2.3.1.157" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170246.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I4D4"/>
    <dbReference type="SMR" id="A8I4D4"/>
    <dbReference type="STRING" id="438753.AZC_1718"/>
    <dbReference type="EnsemblBacteria" id="BAF87716">
        <property type="protein sequence ID" value="BAF87716"/>
        <property type="gene ID" value="AZC_1718"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1718"/>
    <dbReference type="eggNOG" id="COG1207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_15_2_5"/>
    <dbReference type="OMA" id="TAIVEHK"/>
    <dbReference type="OrthoDB" id="1381953at2"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00533"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
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        <property type="entry name" value="Hexapep"/>
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        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
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        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
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        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
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    </dbReference>
    <dbReference type="Pfam" id="PF12804">
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000073644" description="Bifunctional protein GlmU">
        <location>
            <begin position="1"/>
            <end position="448"/>
        </location>
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    <feature type="region of interest" description="Pyrophosphorylase" evidence="1">
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            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="1">
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        </location>
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    <feature type="active site" description="Proton acceptor" evidence="1">
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        </location>
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    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="14"/>
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        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
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        <ligand>
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
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        <location>
            <position position="144"/>
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        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
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        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
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    <feature type="binding site" evidence="1">
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            <position position="230"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
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        <location>
            <position position="319"/>
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        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
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            <position position="337"/>
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        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
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        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
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        <location>
            <position position="363"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
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    <feature type="binding site" evidence="1">
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            <position position="366"/>
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        <ligand>
            <name>acetyl-CoA</name>
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        <location>
            <begin position="372"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
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    <feature type="binding site" evidence="1">
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            <position position="409"/>
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        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <sequence length="448" mass="46869" checksum="25282EC615E860A1" modified="2007-12-04" version="1">MSERSLLVVVLAAGEGTRMASRLPKVLHRIAGRSMLHHVLETTRQAGATRVAVVIGPDREDVAAEAHRVRPDAQVFVQTERLGTAHAVLAARAALEEPADDVLVLYADTPLLRPETLENLRAPLADGAAVAVLGFRPADPTGYGRLLTQGDALVAIREEKDATPDERRVDFCNAGVMALRAREALSILTRIGNANAKGEYYLTDAVEIARADGLSAVATEAEVDEVAGVNSRLQLAEAEAILQGRLRRAAMAGGATLVAPETVFLSVDTRLGRDVLVEPNVVFGPGVTVEDDVVIHAFSHLEGAHLERGVSIGPYARLRPGTRLGEGVRIGNFVETKAALIDAGAKVNHLSYVGDAHVGSNANVGAGTITCNYDGFSKHRTEIGAGAFIGTNSSLVAPVSVGAGAYIGSGSVITDDVPADALALGRGRQAVKEGWAAALRAARGKPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4G9</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1730</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170258.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1730"/>
    <dbReference type="ESTHER" id="azoc5-a8i4g9">
        <property type="family name" value="Duf_900"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87728">
        <property type="protein sequence ID" value="BAF87728"/>
        <property type="gene ID" value="AZC_1730"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1730"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
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    <dbReference type="InterPro" id="IPR010297">
        <property type="entry name" value="DUF900_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014586">
        <property type="entry name" value="UCP033909"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05990">
        <property type="entry name" value="DUF900"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UCP033909"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="425" mass="45914" checksum="169F5D88351806A1" modified="2007-12-04" version="1">MRLMLAARPFRCVMAIAVVLLVTACGGRPPGVLVPVQAPDVPGTSKVSMIVATTRAKATTTTDMFSGERGKAPSFAEITVSLPPDAARQVGEVQWPRSVPGNPATDFVVTDAQDLSMPQAQAWLNRDVAKRPKHRVLVFIHGYNNRFDDAVFRFAQIVHDSGADVTPILFTWPSRGSLLAYGYDRESAVYSRDALETLLTALNKDPAVGEISVLAHSMGNWVTFEALRQMAIRNGRVLPKIKNIMLAAPDVDVDIFNSQWQDLGTPSPNVTIFVSQDDKALRVSQRVWGSRARLGQIDPEQEPFRSEFEARKINVYDLTKLNTPDGLNHGKFAESPEVVRMIGGRIAAQSTITDSREGVGDRIVQVTQGAASAVGQAAGVVIAAPVAVVDSNTRDNLSSQVENLGGTVSSTVHSTTNMMTTPPSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4I3</accession>
    <name>A8I4I3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter nucleotide binding ATPase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1735</name>
    </gene>
    <organism evidence="10 11">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
    <sequence length="510" mass="55978" checksum="C8203C9816994B87" modified="2007-12-04" version="1">MKEILEELENRRVVARLGGGEKRIQAQHGRGKLTARERIELLLDHGSFEEFDTFVQHRCGDFGMENQKIPGDGVVTGWGTVNGRQVFVFAKDFTVFGGSLSEAHAQKITKIQDLALKTRAPIIGLFDAGGARIQEGVAALGGYGEVFKRNVTASGVIPQISLIMGPCAGGDVYSPAMTDFIFMVRDTSYMFVTGPDVVKTVTNETVTSEELGGAKVHTTKSSVADGAYENDVEMLLQTRRLIDFLPLNNQVGVPEWPSFDAPDRVEESLDTLIPDNPNKPYDIKELILKVADEADFFEIQAAYAKNIVTGFGRIEGRTVGFVANQPMVLAGVLDADASRKAARFVRFCDAFEIPIVTFVDVPGFLPGTAQEYGGLIKHGAKLLFAYSQATVPLVTIITRKAFGGAYDVMASKHVGGDVNYAWPTAQIAVMGAKGAVEIIFRSDMDDPEKIAEQTRKYEQRFLSPFVAAERGYIDEVIKPHSTRRRIARALAMLRSKKVEQPLKKHDNLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5C2</accession>
    <name>A8I5C2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">cobD</name>
        <name evidence="11" type="ordered locus">AZC_2259</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170786.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2259"/>
    <dbReference type="EnsemblBacteria" id="BAF88257">
        <property type="protein sequence ID" value="BAF88257"/>
        <property type="gene ID" value="AZC_2259"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2259"/>
    <dbReference type="eggNOG" id="COG1270">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054212_0_1_5"/>
    <dbReference type="OMA" id="NSGYTMA"/>
    <dbReference type="OrthoDB" id="2029688at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00380">
        <property type="entry name" value="cobD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 10" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="299"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="324" mass="33955" checksum="3038A069CB0510E9" modified="2007-12-04" version="1">MAFDLTCVALLVEGLTGYPQPLFRAIRHPVVWAGTLISALESRLNRTTLPGPARKRNGVLTVIVLLACAMLPALMLEAFLRQFALGVVLAGILGSVLIAQHSLYTYVAAVATALEKGGLAAGRRAVSHIVGRDPEQLDVAGVTRGAIESLAENFSDGIVAPTFWMLVGGLAGGAGYKALNTADSMIGHRNPRYEDFGWAAARLDDLVNLPASRLSGLLIVLAAGLLPGCSPKEAWRAMLRDAPHHRSPNAGWPEAAMAGALGISIAGPRSYGGVPAQAAYMGNGRRDIDARDIRAALRLYVAADALLVVFVTLIALAGLVIARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5F6</accession>
    <name>A8I5F6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">iclR</name>
        <name evidence="6" type="ordered locus">AZC_2273</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2273"/>
    <dbReference type="EnsemblBacteria" id="BAF88271">
        <property type="protein sequence ID" value="BAF88271"/>
        <property type="gene ID" value="AZC_2273"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2273"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_6_0_5"/>
    <dbReference type="OMA" id="RHSMRMF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="4">
        <location>
            <begin position="27"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="5">
        <location>
            <begin position="87"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="275" mass="29384" checksum="5E18DDD5A396ACCD" modified="2007-12-04" version="1">MSMSVASVGNGPDESGPESKAAGPAGSQAVMRALDVLEAAASDPIDLGTLASSLGLTRSTAHRLASGLAARGYLRLAPGEGYSLGPKVMELGARARAQRPLARIARPHLEALASETEDTVHLGVLEGDWALYLDKLPGRRRFEISSRVGERHPVWSTGLGKALILDGDAATWERFFEIGSARGPNREQARTAWLGRMSNYADWGYAFDLEENEPRVRCVAAPIRDASGLTVGAISVSSASHYMDDARMKALSQMVTGTADRISGELGWRRRPSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5M2</accession>
    <name>A8I5M2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SmpA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_2298</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2298"/>
    <dbReference type="EnsemblBacteria" id="BAF88296">
        <property type="protein sequence ID" value="BAF88296"/>
        <property type="gene ID" value="AZC_2298"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2298"/>
    <dbReference type="eggNOG" id="COG2913">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104933_1_0_5"/>
    <dbReference type="OMA" id="WRIFKRY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026592">
        <property type="entry name" value="BamE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037873">
        <property type="entry name" value="BamE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007450">
        <property type="entry name" value="Lipoprotein_SmpA/OmlA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37482">
        <property type="entry name" value="PTHR37482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04355">
        <property type="entry name" value="SmpA_OmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SmpA_OmlA" evidence="4">
        <location>
            <begin position="95"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="212" mass="22703" checksum="CC18C8F52DC64DD0" modified="2007-12-04" version="1">MPRGSVVITEPIVHERALAAPIRMMWRIFKRYSVAPGRSAQRSASSLPVRRVSAATTAAALALAGLSLAACGSLPPMGVAAGNPPTGIVRTYQRGYVLSDGALEQVPVGSSREQVLLVLGTPSTVSTLNGDVFYYISQTEKRVAFLKPEITDQKVLAVYFGKDKRVTRIANYGLQDGKVFDFVSQTTPTGGEELSIIKQLISATDFSPGFAR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5N7</accession>
    <name>GCS2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="1">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="1">GCS 2</shortName>
            <shortName evidence="1">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_2303</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I5N7"/>
    <dbReference type="SMR" id="A8I5N7"/>
    <dbReference type="STRING" id="438753.AZC_2303"/>
    <dbReference type="EnsemblBacteria" id="BAF88301">
        <property type="protein sequence ID" value="BAF88301"/>
        <property type="gene ID" value="AZC_2303"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2303"/>
    <dbReference type="eggNOG" id="COG2170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044848_1_0_5"/>
    <dbReference type="OMA" id="LIFGLHV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
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        <property type="entry name" value="gshA_cyan_rel"/>
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    <keyword id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <sequence length="386" mass="43163" checksum="54616BD4AB2C254F" modified="2007-12-04" version="1">MLRLGSLASREVRMSNDYRFGIEEEFFVVDAETKAALRRMPSGFFDALRDRLGDSITVELLQSQLEMATAPTDRIGDALDELRDLRHIAGRVAAEHGLGFIAAGTHPTASWDNVRATKANRYDGLMQDLQMLGERNMVCGLHVHVELPDPDLRVDVMRRITPYLPHFIALSTSSPFWGSRQTGLMGYRLAAYDELPRTGLPELFEDNAAYEEYVAALVGARAISDSSYVWWAIRPSQKHPTLELRAPDACTRVEDAVALAALYRSLVRFLVRHPEHHRHIGAVDRAIANENKWRAQRYGIHGSFVDLAEQRAIQVRDALDQLIALVADDAEDLGCLDALLHLRTIPDAGTSADMQIAVYQEAHHRTGNRGEALQAVKTWLAHATLQ</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2323"/>
    <dbReference type="EnsemblBacteria" id="BAF88321">
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        <property type="gene ID" value="AZC_2323"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="183" mass="20283" checksum="493EE55D45473801" modified="2007-12-04" version="1">MVHIHITGASGSGTSTLGAAVAEVLGIRHLDTDRFFWMPTEPPFTTPREVSARLALLQQEALPDVGWVLSGSALKWATPLEPLYDLIVFLHLDPAVRMERIRLREEQRYGERIRPGGDMAEVSRAFLEWAESYDTAGPERRSRAAHEDWLQRQSAPVLRLDSVEPVEALLAAVLDHPAGGAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8I633</accession>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720878" description="DUF2059 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2059" evidence="2">
        <location>
            <begin position="104"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88355.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="178" mass="19075" checksum="9ECE114E5B5E7F55" modified="2007-12-04" version="1">MAVFPSVRSFGAGLLALGLMAGSALAQTAAPAAPAALPQPTAAQMQIARQLVEANGEAHAFDGIIPNIVDGAALGFLQTNPDLAPKLRDTAKALRPEFEKRKGELMDILAASYAQRFTEQELKDALAFYQTPVGKKLVSDRAQIVQQAVIAIQAWGAKLNSEAMNRIREEMKKQGYDL</sequence>
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    <accession>A8I6E9</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
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            <topology evidence="1">Single-pass membrane protein</topology>
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    </comment>
    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="STRING" id="438753.AZC_2399"/>
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        <property type="gene ID" value="AZC_2399"/>
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            <end position="42"/>
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    <evidence type="ECO:0000256" key="5">
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
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    </evidence>
    <sequence length="286" mass="30769" checksum="7856FE47199C012E" modified="2007-12-04" version="1">MRLDDFKPSSNVEDRRGMNFPGGGGGLGIGTVIVVGLLGWALGINPMTLLGGLEALQGSGQQQTTQGRKGPPDDQVAQFAAKVLATTEQVWTDQFRQQGRTYTKPTMVLFSGRVQSACGDASAAVGPFYCPVDQKIYLDLDFFRELATRFGAPGDFASAYVIAHEVGHHVQNLIGILPKLQQAQRNAATQREANGISVRSELMADCLAGVWANHANADYRVLEPGDVDEGMKAAAAVGDDRLQRQATGTVVRDNFTHGSSQQRVTWFMRGLKAGNMNQCNTLQGTP</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
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            <topology evidence="2">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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    <comment type="similarity">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="75"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="279" mass="29494" checksum="67CCD2873632B528" modified="2007-12-04" version="1">MKGFWSRFCRHKAAVAGLVVVVLLVAVALAAPYLYPASPWKMVQRPFLAPFVNAAVPLGTDTLGRNVASGLVHGARVSLLIGTVSTLVALVIGVPIGAIAGYFGGIVDDLLMRVTEFFQTVPSFALAIVLVAIFQPSLVSIVTAIGIVGWPPVARLVRGEVLAQRKREYVEAAILCGQSHFTIITRQILPNVVSPIVVLASLMVATAILLESSLSFLGLGDPSVMSWGYMVGAARTVVRQAWWLSVLPGLAIVIAVLAINLVGEGLSEALDPRSARDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8I871</accession>
    <name>A8I871_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2218</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2218"/>
    <dbReference type="EnsemblBacteria" id="BAF88216">
        <property type="protein sequence ID" value="BAF88216"/>
        <property type="gene ID" value="AZC_2218"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2218"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000496_0_0_5"/>
    <dbReference type="OMA" id="DTFDHRT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042157">
        <property type="term" value="P:lipoprotein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000074">
        <property type="entry name" value="ApoA_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01442">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2114"/>
            <end position="2270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2198"/>
            <end position="2214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="2385" mass="255373" checksum="7573089E5503EEB2" modified="2007-12-04" version="1">MKSPKKIQDPTEAALSAIQEALTLQLDAAEPAAPQPPGADDRPAPTKSPQPAAQQSTPPQAAAQPPRDAGNGRRRLDVAERRAANDDRQTIGQLLAALQRRSSPAPYWWALIGSVVWMGIGVALALATQRAAISDISSLQGVIESPLLLAIIAGIILPPVGFFGTASVVRRTRDLQLIARAMTEVALRLAQPEAIGTEAVVSVGQAVRREVAAMGEGVDRTIARAAELETVVRSEVSLLERAYEENELRIRNLIDELQAERQNILIHSERLREGIVDADKLLAHDVKDIAERVNASVSGAADRITSLFEERSAAITGELSRIGETVIGAISAKGSELIDRLETTGAEIRGDLTRSSDAVSAALKSRTDDLAQNLAASTAEVTELVGRWSEDVRVNADTARETLIQALVESSALVHDELTVRAAEVNSTFRSTAESVVYELSNRGGELIRKVQDTGERVAETIAQRGGDIADRIEITGSRIHEDVTVRGEVLQQQLSDTAERVAEALERTSAAVTDALAVKGDEIAASLTQTANEMSERFDGIASDVNNVMGSQGEAFNNAFRLNADQMVATLGTNSEALEQMLTSRLSALDEAISVRGFALADRVGQDSALVAKAIHDSITAFDASIREDAPELVAQLADRIEAVSETLGTKLSDLDSRLGATGETVATVFDTRIAKVEETLSGRSGDLAALIEQRATEFAEVMSEGTRVATEALEQTSGALSSTLDERLAKIEETLSVRGGELTATIERQAADFTAAMSDGTRAATEALEQTSGALSSTLDERLAGIEDLLSTRGSELTAAIEQRATDFTAAMSEGTRAATEALEHTSGALSVALDERLSQVEETLAARSGELTAAIEQRAAEFAQAMSEGTRAATEALEQTSDALSSTLDERLSRIELALTAGTEAVAQSIDGRADAFVQAVAEGTRVSQDAFDQTAETIVNAIDQRLVRIEETLDERARSLTEALQERAMDFDRVVSEATSSATTLFEQTSGTVANAVEQRLAHLEQVIDTRARTLTEALHARAQDFNRSVSEATGSVSEVFEQNSTSVAALIDERLGQIEQLFDERTQGLETRAQDFTKAMTESTREAATAFEETGELVTTVIQERLAHVEQVLSERTDSLTSTLDGRASAFAEAVENSTRDANAAFEQTSQAVANAIGERLGQIEQVLDERTVSLTQMIETRGEAFARAVADSSREANSAFEQTSNAVAAAIGEKLGQIEQVLDERTHSLTQMIETRGEAFARAVAESSREANSAFEQTSNAVAAAIGDRLTQIEQVLDERAKSLTGALESRASEFARVVTESTQNATHTFEQTGEAVSASIDQRLGEIERTLDERARNLTETLETRAADFTRAVSEGTRLASEAFEQTSEAVTITLDQRLGRIEQTLEQRTQSITETLANRTVDLARAITDGSQSVSQALDHSMSTLDTYFASRSKAIGELIASRAESVSEAIGARANDIAATLDGRVQRIEDLVTGRFENISGLIEERGLSVADTLATRIEAVTGQLRTGADEIEQSLNGLADNVGRTLNAQAEGVAATLRTSAGQVEFSLTNLSENVGRALTSQAEQVTGTLTTNASEMERSLTTLADQVGRTIGTKAAQAAETLKTSSSEIEQSIGSLADSVGRTIGTKAAQAAETLKTSSSEIEQSIGSLADTIGRSIGTQAELVTIALRSGAGEVEDRINAAADNVTRALSTRAEAAVAVLQNGTGDLDGRLSALAEQITRTLTDRTDRAITTLRIGASDVEERVERLIQNVASTMTGQADDMTEKLNARLAEIAGLFDTKSGAFLGSLEGTSRQAVYEIRAANDRLRGDIEGILDRLSGANASFQSAMGQVFENIGTFEGGFADKAEALRVSAETIGSSAEATVARLDGQVQSLKAVAASTLNDIASLTQRFESQGRLVLKASETLGETHEQVDAVLSNRKAAIEDLTATIAERVAQLEQGLQAFQSTVSKTLGNAQDRARQIANVVADTTEASARALDNQHQALSAAAEAERARLTEALKTNYDAALKDVNHVFEEGGRRFLDVARELKSAASEVQQSIELAREEMKRGILELPGETEASAATMRRAVAEQIKALAELNEIVARQGQALDVAAAPARPLPRATAPALQPPARPVETTRVPAAPAPREVPAREAYGPAAPVPQGPVHPGPVMPAPAAQAQAPAGPPQREIPQVVRPRIEAPVAETQRRPAPRREDERTAVTEARPAPRVPEARAPRQAPREEGRGGWLSDLLARASNEPEDGAKTAPQRQPTRAARPHHHMIESLDSLSVDIARMIDHDAAVELWERYKRGERNVFTRRLYTMQGQQAFEELRRKYRTDAEFHETVDRYIAEFDRLLEQVAADDRGNVLTKTYLTSDTGKVYTMLAHAAGRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8D6</accession>
    <name>A8I8D6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <ecNumber evidence="4">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2649</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2649"/>
    <dbReference type="EnsemblBacteria" id="BAF88647">
        <property type="protein sequence ID" value="BAF88647"/>
        <property type="gene ID" value="AZC_2649"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2649"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_7_2_5"/>
    <dbReference type="OMA" id="ICAPEAD"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
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        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="369" mass="39827" checksum="6E8CC7973341D35B" modified="2007-12-04" version="1">MTGRRHAIDRVQDAGQISNNYLKSSSTELNSRLRLLARRPISSRSAGGQQARRGTRPPMQKITGSFVAIVTPFNKDGSVDFVAFRELLKFQEDNGTAAILIMGSTGETSMLSAEEKKKVIVETAKMKTAKMPLFYGCTGNNTETTIENVRFAKDNGADGAILAAPAYICAPEADIEGYFLDVADATDLPLGIYNNPPRVKSDLHWDNLLRIFKHPNYVIHKESTTRVGQVAQVLAARPDVSVMCCDSPNLGLVVPTMSLGGHGTANMTGNIAPAELVAISRPWNGDEGAAAFKEAYLGLLPMLHYTYSAINPVAVKSLMKAVGLPVGELRKPLRGLEGEALAKGVRIVQELELDRKYGFKIAPLSAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8F1</accession>
    <name>A8I8F1_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Oligopeptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2654</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2654"/>
    <dbReference type="EnsemblBacteria" id="BAF88652">
        <property type="protein sequence ID" value="BAF88652"/>
        <property type="gene ID" value="AZC_2654"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2654"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_5"/>
    <dbReference type="OMA" id="LMMLERP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="286" mass="31040" checksum="F4EC284472B7518D" modified="2007-12-04" version="1">MGLAPATSGTVRLDGEVISGLPYAQLRPLRRRMQMVFQDPYASLNPRKRVADIIAEPLQVHGIGTAQDRRAKVQELMARVGLPVDAGGRFPHEFSGGQRQRIGIARALALNPALIVADEPVSALDVSVQAQVINLMVRLQKEMGLSYLFISHDLAVVHYIADRILVMYLGKIVEVADRARVWKQPLHPYTAGLLAAHPAPDPAGAHRPRVRITGDMPSPTNPPSGCRFHTRCPFVENRCTAEAPALRALPDGRQVACHRVEVTGAGEARSPSEILSLEPITAPAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8L8</accession>
    <name>A8I8L8_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <dbReference type="EMBL" id="BAF88681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="615" mass="63280" checksum="709BBC5FB1C7B778" modified="2007-12-04" version="1">MFSNLWVPAGVACFATSRCQTVDNLYTNSLSVKSKSPPPDGIGGWERTPHDGSNTGRCERCACHGDDHRGRRGAARPRGRDADNGARPPRPSAPAPEPSCGQRARRLLPYGRVPGMRAACGWRAAPSLPDACASRHGRRAAGRAVSHDVIILGAGPAGANAALAAAESGLRVVLFDQQPEAGGQVWRAPLPGLSMPSSPELSSGDALRARLAASAVECRFGRTVWSVGGHFRVDAVGPDGNEHVEAPRLVAATGAHERVVPFPGWTLPGVIGLAAATVLLKSHGVLPGQRVVIAGCGPLLAAVAAGVLKGGGTIAAIADLAGPSDWLRALPALASQPRLLARGAGWALKIGGARVPVLFRHGVRAAEGDDALSRVSLAPVDAEGAFIAGPERVMEADALCVGHGLVPGAEVPRLFRVAQAFDRQRGGFVPKLDAEGRTSLNGLYACGDGVGLRGALVAEAAGRLAGLACAHDAGALTAATFAGVSAPAREAIGQARAFSDAMGDMMALRPAQVAAIPPETTVCRCEDVTRADIESAYADGAREMNQLKQFTRCGMGPCQGRFCGDVAAEILAAKVGSREEVGTFTARPPLRPVALADLLGSFDYSDIPIPPPAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8P2</accession>
    <name>A8I8P2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribulose-bisphosphate carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2687</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RuBisCO large chain family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2687"/>
    <dbReference type="EnsemblBacteria" id="BAF88685">
        <property type="protein sequence ID" value="BAF88685"/>
        <property type="gene ID" value="AZC_2687"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2687"/>
    <dbReference type="eggNOG" id="COG1850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031450_3_0_5"/>
    <dbReference type="OMA" id="IHGHPDG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016984">
        <property type="term" value="F:ribulose-bisphosphate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033966">
        <property type="entry name" value="RuBisCO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020878">
        <property type="entry name" value="RuBisCo_large_chain_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000685">
        <property type="entry name" value="RuBisCO_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036376">
        <property type="entry name" value="RuBisCO_lsu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017443">
        <property type="entry name" value="RuBisCO_lsu_fd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036422">
        <property type="entry name" value="RuBisCO_lsu_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42704">
        <property type="entry name" value="PTHR42704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00016">
        <property type="entry name" value="RuBisCO_large"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02788">
        <property type="entry name" value="RuBisCO_large_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00014">
        <property type="entry name" value="RuBisCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51649">
        <property type="entry name" value="SSF51649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54966">
        <property type="entry name" value="SSF54966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00157">
        <property type="entry name" value="RUBISCO_LARGE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RuBisCO_large_N" evidence="6">
        <location>
            <begin position="15"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="RuBisCO_large" evidence="5">
        <location>
            <begin position="139"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="422" mass="44721" checksum="4E7C2E1AA21540A5" modified="2007-12-04" version="1">MMSRFEASYLIETPLDPVKVAQVMAGEQSSGTFTRVHGETDELRARSRAEVLSVVDFGTSDTPSLPNAYLDRRSVAGPYRRARIRLAFPVANVGANLPTLAATAAGNLFDLGEVTGLRLESLSLPDAYRRAFDMPRQGLAGTRALTGVETGPLVGSIIKPNVGLSAEETGELVGQLCAAGLDFIKDDEICANPSHAPLAARVPAVMRRVRDHAERTGKKVMVAFNITDETDAMRRHADLVAREGGTCVMASLNWCGFSAIQTLRRSTDLALHGHRNGYGALSRAPLLGIGFQAYQVLWRLAGVDHMHVHGLKGKFAQEDAEVIESARDCVTPLSSSEDDRVMPAFSSGQWAGTVPATYAATGHADLLFMAGGGIMAHPDGPSAGVASIREAWEAVMAGEGLPEAAQRAPALAKALAFFGSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8S6</accession>
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        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
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    </protein>
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        <name evidence="6" type="ordered locus">AZC_2699</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
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        <subcellularLocation>
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        <subcellularLocation>
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        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88697.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
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    </evidence>
    <sequence length="353" mass="35803" checksum="E5058EA5349871A3" modified="2007-12-04" version="1">MTSIITNNAASVALATLRSINDSLNTTNDRVSTGKKINSAADGAAYWNISTTLTSDNGALGAVKDAINLDMSSVKTTNTGLTQIMNSLNTIKQALVSAQSSTADRTSLQKNIANAVSDISSAASSAVVNGANWLSVDSSATGFNANKSLLANFSRASGVVTVGTTTLDTGAFAVYDAKTNGTATGTSSTIDTAVTAVATSASSGTGALTVAVGTGAGQLKGFMDTTYSISGTVNGTTVAAFTASIANIDISSLTSSDVDLAKLSSYMKIVSATIDGLQAGSTALGTTQTRLTSQQNFAQSLIDINTSSIGSLVDANMEEESTKLKALQTQQQLAVQSLSIANNSTSNIMTLFR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171225.1">
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    <dbReference type="STRING" id="438753.AZC_2701"/>
    <dbReference type="EnsemblBacteria" id="BAF88699">
        <property type="protein sequence ID" value="BAF88699"/>
        <property type="gene ID" value="AZC_2701"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2701"/>
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        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="DJ-1/PfpI"/>
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        <property type="entry name" value="Homeobox-like_sf"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="233"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF88699.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="335" mass="35869" checksum="64115A411C13302A" modified="2007-12-04" version="1">MSTRRPARIIPVLAVVPPRALLLDLAGPIEVLRQANQAQDDVRFDVTYVGPSEQVHSSIGLPLAGIRPLPRSVPDGALVLVSGAVETPLGSPSSTAAQDEADAASIVEWLRTAIRPQVRLATICSGALLAARAGLLDGYDCTTHFGTLAQLAALAPHARVRENRLYVEDRGRLTSAGVTAGIDLMLAFVAREVGHATAVAAARMLVVYLRRGGGDPQLSPWLEGRNHIHPAIHRAQDAVGADPARDWSVEAMADVAGTSPRNLSRLFNEHAGMSVTEYVNRMRIALAHDMVVHSRLDMDAIAESSGFSSARQFRRAWNRLQAVPPGQLRAQLAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I905</accession>
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            <fullName evidence="3">Hydantoinase A</fullName>
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        <name evidence="3" type="ordered locus">AZC_2728</name>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="protein sequence ID" value="BAF88726.1"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF88726">
        <property type="protein sequence ID" value="BAF88726"/>
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        <property type="entry name" value="Hydantoinase_A"/>
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    <dbReference type="PANTHER" id="PTHR11365">
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="191"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="517" mass="54021" checksum="09D0DEDE62C72D33" modified="2007-12-04" version="1">MRRIGIDVGGTNTDAVLIDGTTVIHSVKRATTADVTTGILDALAALRQHPATRGKVDAVVIGTTHFINAVVQRRHLQKVAAIRLGMPASAALPPFCDWPSDLGTLVNGEVFMLEGGHDYDGRPFMPLDTAGVRTAARRIRDQGIRSVAISAIFSPLDPSGEEQARDILLEECPDIAVTLSHDLGRIGLLERENAALLNAALRDLAATTVSAFRKAIADSGIDAPLYLTQNDGTVMQAEVATQFPVMSFASGATNSMRGAAHLSGLEDAMVVDVGGTTSDIGQLRHGFPREANSVVEVGGVRTLFRMPDLLSIGLGGGSHVDPDTGRIGPLSVGYRLTQDALVFGGTQLTATDIAVAAGLLDIGDRARVQHLSAGLITAALENARQQLEDNVDRMKTEAGEVPLLAVGGGAFLAPEKLTGCSQIVRVPHGDCANAVGAAIAQVSGETDQVFRDLSRDAAIEAALTIARDRAVAAGADRDSLKTVEVEDMPIAYLPGNALRVRARVAGGIATPDVRDAA</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2732"/>
    <dbReference type="EnsemblBacteria" id="BAF88730">
        <property type="protein sequence ID" value="BAF88730"/>
        <property type="gene ID" value="AZC_2732"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2732"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006807">
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        <property type="entry name" value="C-N_Hydrolase"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="5"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88730.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="313" mass="34243" checksum="4A5C6C2733287F2A" modified="2007-12-04" version="1">MTRVLRLAAAQMGPTSRTEPRAVTLDRMIRLLEAAAADGAQLVVFPELAFTTFFPRWLLDDAELLASFETAMPNPGVQPLFDRARALGVGFYVGYAELTPAGQRFNSSITVGPDGAILGKYRKVHLPGSVEPRPGDRFQQLEKRYFEYGDLGFPAFRGPQAWQSPILGMLVCNDRRWPEAWRAYGLQGVELMLMGYNSAAYDPNGGNTEDAALRTFHSTLVAQANAYMNATWAVSVAKAGDEDGSALIGGSCIVDPNGVLVAQAKTLEDEVLVADCDLDACRQGKEKMFNFAAHRRPEHYRRLVDQVGAVLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BMP lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171337.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2813"/>
    <dbReference type="EnsemblBacteria" id="BAF88811">
        <property type="protein sequence ID" value="BAF88811"/>
        <property type="gene ID" value="AZC_2813"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2813"/>
    <dbReference type="eggNOG" id="COG1744">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038813_1_1_5"/>
    <dbReference type="OMA" id="IGHGREF"/>
    <dbReference type="OrthoDB" id="603910at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Bmp" evidence="3">
        <location>
            <begin position="34"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="335" mass="34563" checksum="9D627AD53203C872" modified="2007-12-04" version="1">MVRLDRRHFLFGSALCGLAAWPLMQSVARAAQPKLGLLLPGRRDDGGFMQAGFSGFEAAAAELKADVVVVDGVRPQKDDLVAALRRIAAEGPSVIAAHGGQCNEAAKIVAADHPRIQFLVIQGGVEGANLTSYEVLQEQSAWLAGAAAALMTKTGTVGHISGIRVPPGLKGRAAYAAGVAHARPGVKLLTTFCGEQDDAALAAKVTAAQADADADIIFTMLNAGRTGAIEACRARKIHQIGNVRDWVPVAPDVFVASAIADVSVAMRDAVSDAVSGRLVPGKHVKLGVSSGDAVRLALAPGVPEEVRVAITGYTADIAAGRIVVPTAYDGPEFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA12</accession>
    <name>A8IA12_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2450</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NtaA/SnaA/DszA monooxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170976.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2450"/>
    <dbReference type="EnsemblBacteria" id="BAF88448">
        <property type="protein sequence ID" value="BAF88448"/>
        <property type="gene ID" value="AZC_2450"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2450"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022256_1_2_5"/>
    <dbReference type="OrthoDB" id="1591714at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01095">
        <property type="entry name" value="Nitrilotriacetate_monoxgenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016215">
        <property type="entry name" value="NTA_MOA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000337">
        <property type="entry name" value="NTA_MOA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03860">
        <property type="entry name" value="FMN_nitrolo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="3">
        <location>
            <begin position="18"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="141"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="213"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000337-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="434" mass="47122" checksum="35CBB2A26CD2D791" modified="2007-12-04" version="1">MKRQMHLGLFLLGTGSHIAGWRMPGAVDSFQDIEAVCEIARTAERAKFDLIFMGDNLNADPAAHPSYTARLEPLTLLSAVAMATERVGLGATVSTTYSDPFTVARAFASLDHISHGRAAWNAVTTAAPAAAANFGTQHPDHARRYEIAGEFLDTVKGLWDCWADDAIVADRESGLYIDPARVKPLDHEGAFFKVKGPVNIGRAPQGHPIISQAGGSEPGQQLAARTADLVFAVVQDIDEARAGYQALKARLPALGRRPEDVCVLPGVMPVVGRTDREARDKLNALMRHVNASNALGMLSERFGVDMSAYDLDGPIPELPKADTYHSFTGVMLAKARRESMTLRDLYNLVAAARGHWVLCGSAESVADTLQDWFETGAADGFNVMPPYFHEGFTDFTDLVVPLLQERGLFRADYEGTTLRDHLGLQRPANPNFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAE0</accession>
    <name>A8IAE0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_2497</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
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    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="258" mass="27293" checksum="58232191DFA5F3D2" modified="2007-12-04" version="1">MERPMLSRTGLRAALAAVAALGLTATTVLPAAAFTDQEKAELGPLIRDYLLKNPEVLQEAIAVLEKRQGEAEAQARAKTLASIKPKVFDSPRGVVIGNPKGNVTLVEFFDYNCGYCKHTLSDINALVKNNPNLRVVLREFPVLGPGSVEAAQVAVAVRMVAPDKYKAFHDALLSGRGQADRARALAAAKEVGIDVAQLQKQATSPELNATLDESMEIAQALGLNGTPSFVIGDEVIVGAVGLEKLQEAVTKNGKTAAN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBI0</accession>
    <name>AROQ_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="1">3-dehydroquinase</shortName>
            <ecNumber evidence="1">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroQ</name>
        <name type="ordered locus">AZC_3073</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171597.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IBI0"/>
    <dbReference type="SMR" id="A8IBI0"/>
    <dbReference type="STRING" id="438753.AZC_3073"/>
    <dbReference type="EnsemblBacteria" id="BAF89071">
        <property type="protein sequence ID" value="BAF89071"/>
        <property type="gene ID" value="AZC_3073"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3073"/>
    <dbReference type="eggNOG" id="COG0757">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090968_2_0_5"/>
    <dbReference type="OMA" id="CAGIVIN"/>
    <dbReference type="OrthoDB" id="1872106at2"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071577" description="3-dehydroquinate dehydratase">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="101"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="1">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <sequence length="147" mass="15451" checksum="DC57024F8358F915" modified="2007-12-04" version="1">MSDTIHVLNGPNLNLLGTREPGIYGAATLADVEALCRTTAAQHGLELVFRQSNHEGDLVDWIQAAAGSVGVVLNAGAYTHTSVALRDAIAGTGVPAVEVHLSNVFAREPFRHHSYLSPVVRGVICGFGPQSYVLGITALATTRPARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBT6</accession>
    <name>A8IBT6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative ATP phosphoribosyltransferase regulatory subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3117"/>
    <dbReference type="EnsemblBacteria" id="BAF89115">
        <property type="protein sequence ID" value="BAF89115"/>
        <property type="gene ID" value="AZC_3117"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3117"/>
    <dbReference type="eggNOG" id="COG3705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025113_6_0_5"/>
    <dbReference type="OMA" id="YYTGFEF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="2">
        <location>
            <begin position="70"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="438" mass="45985" checksum="87D6C5B1B33D585C" modified="2007-12-04" version="1">MLALLISEHCAALKAPSAVTGWSRTPSFARSPHETSSGRPSRICGPGRPQRSRAAMPIEAQSPPLLRDSSALDEALMARFASAGFLRLDPPILQPADAFLDLSGETIRRSMFLTSGEDGQELCLRPDLTIPVAREVQRLHLPMPAAVSYLGPVFRSHSGGAGEFRQAGVESFGRADTAAADADILALGLETCAIYGVPDPEILIGDVGLFSAVLEALPLAPAWRRRLMKDFGQGRLDEDIANLSESEAKGTAAVHAGVLSALAGSDPDAARALITDLLSIAGITTVGGRTVSEIAARFLEQAALEGNGLSAETAAILSRYLAITGAPGPALEQVRALANEARIDISGALAAFEERASHLAAHGVNLSEVEFSAAFGRPLDYYSGMVFELSDPEGRVAAPLVAGGRYDRLMSRLGAETVVPAVGFAAWVERLALLESQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBZ6</accession>
    <name>A8IBZ6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glutathione S-transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3140"/>
    <dbReference type="EnsemblBacteria" id="BAF89138">
        <property type="protein sequence ID" value="BAF89138"/>
        <property type="gene ID" value="AZC_3140"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3140"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_12_2_5"/>
    <dbReference type="OMA" id="VDIGTIA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034343">
        <property type="entry name" value="YibF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42673:SF12">
        <property type="entry name" value="PTHR42673:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="17"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="213" mass="23017" checksum="C3F625808A6B9B78" modified="2007-12-04" version="1">MRPPKSPRNAHPSGAAMPLRLRHSPASPFVRKCRLAAAVLGIPLELEPCDTTDPTDSISTQNPLGKIPALLLEDGEVLFDSPVIVAYLDHLGGNKLIPAEPKARFAALKLEALADGMADAALLQIYEHRYRPEGMQVQSWLDKQAAKVSRALESLEANPPSEALTNGAIALASALGYLDLRFKGEWRSGHPKLVAWLEAFKAKVPAFAETTVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC89</accession>
    <name>A8IC89_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3176</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the flavin oxidoreductase frp family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3176"/>
    <dbReference type="EnsemblBacteria" id="BAF89174">
        <property type="protein sequence ID" value="BAF89174"/>
        <property type="gene ID" value="AZC_3176"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3176"/>
    <dbReference type="eggNOG" id="COG0778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070764_0_0_5"/>
    <dbReference type="OMA" id="GMCLGYP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02146">
        <property type="entry name" value="NfsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016446">
        <property type="entry name" value="Flavin_OxRdtase_Frp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43425">
        <property type="entry name" value="PTHR43425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005426">
        <property type="entry name" value="Frp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="4">
        <location>
            <begin position="45"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="284" mass="30428" checksum="09B85D8E1225F2EE" modified="2007-12-04" version="1">MMSDTLIAEKPVVSAAEAALERRYREPLAGADHPWNAVIQSLVDHRTVRAFLPKAVSEETLQVLVAAAQSAPTSSNVQAWSVVAVRDPARKARLAHLAGDQKHILEAPLLLVWIADLSRAAGIGERAGLTLEGLDFTESFLIAGFDAALAAQNALVAAESLGLGTCYIGALRNHPIEVAETLGLPRKTFAVFGLVVGHPDPARPADVKPRLPQAAVLHHETYDLAGQAEAVARHDAHSLAFRAEQKLDATPWSQQLIGRLHTVAALKGRHLLKQALEKLGFALK</sequence>
</entry>
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    <name>A8ICH9_AZOC5</name>
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        <submittedName>
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    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3211</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3211"/>
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        <property type="gene ID" value="AZC_3211"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3211"/>
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    <dbReference type="OMA" id="MGEATCH"/>
    <dbReference type="OrthoDB" id="1094766at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="3-OHbutyrate_DH"/>
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        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
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        <property type="entry name" value="SDR_fam"/>
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        <property type="entry name" value="GDHRDH"/>
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        <property type="entry name" value="SDRFAMILY"/>
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        <property type="entry name" value="SSF51735"/>
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    </dbReference>
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        <property type="entry name" value="PHB_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="259" mass="26842" checksum="68674FE2A4E6618A" modified="2007-12-04" version="1">MKGRNAVVTGSTSGIGLAIARSLAAEGCNVMLNGFGEPAQIEMVRREMAETTGCTIGYSGADMGRPEEVRALIAAAQNTLGTVDILINNAGVQHVAPLVAFPEDKWDLLLAVNLSAAFHATKAVMPAMLARGFGRVVNIASALGLVGAPHKPAYVATKHGLIGLTRSVALEVAQGGVTCNVVCPGMVMTPIIEMQVADQARVTGLPPEEVVREVFLENQPIRRPVKAEEIAAAVVFLCSEAAAGITGTVLSVDGGYTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="4">Putative selenocysteine lyase</fullName>
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    <gene>
        <name evidence="4" type="ordered locus">AZC_2863</name>
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    <organism evidence="4 5">
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    <reference evidence="4 5" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="evidence" value="ECO:0007669"/>
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        <location>
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            <end position="442"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="452" mass="47759" checksum="F71895E4AE10BA42" modified="2007-12-04" version="1">MCRRAEEPWRHGGPDAFPRLTPRGRHRSRHRRRDAHPMGGRDRFAGFRPRSGAAAMMAGPFTSSEIAELRAQTPATGHRIHLNHASTSLMPRAVTGVMTDFIALEQAVGTHAAMEAHARDIEGVRHAVAALLNCPPRNIAFVETASRGWALALGACVSSGLRRIALARSDWGANILNASAMATGTALEVSLVPIGPLGQSSPAALVQAGAGGAVAFSLVPTSSGVAADVETIAEEARRREALVMIDAAQAVGQIPVDVSALGADVLVFPARKWLRGPKGAAVLFVSDRILAQAGPPLRDLGGGTWSGADDFLWRDDARRFESFEFNPAVRLGLGAAARLAREVGPGRIAARIRALVDLACTRLAALGAPLPMEAGDPAATGIMTWADRRRDVGALVEALRQRGIFAAGIGESQARLALEARGGPIIRASVHYFNTEDEIEAFATGFAALWHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICZ7</accession>
    <name>A8ICZ7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acyl-CoA transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2864</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171388.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2864"/>
    <dbReference type="EnsemblBacteria" id="BAF88862">
        <property type="protein sequence ID" value="BAF88862"/>
        <property type="gene ID" value="AZC_2864"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2864"/>
    <dbReference type="eggNOG" id="COG1804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_0_0_5"/>
    <dbReference type="OMA" id="VGAWANQ"/>
    <dbReference type="OrthoDB" id="969868at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003673">
        <property type="entry name" value="CoA-Trfase_fam_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044855">
        <property type="entry name" value="CoA-Trfase_III_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023606">
        <property type="entry name" value="CoA-Trfase_III_dom_1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02515">
        <property type="entry name" value="CoA_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89796">
        <property type="entry name" value="SSF89796"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="380" mass="40529" checksum="40262D0EC0CC8DD0" modified="2007-12-04" version="1">MTDAPSDLPLAGVRVLDLSRILAGPWCAMVLGDLGADVVKVEHPERGDDTRDWGLRTGRTTTSYFDAVNRNKRSVSIDLATPEGLAQVKAMARDADIVVQNFKTGGADKLGLGYEALAAENPRLIYCSISGYGSEGPEASRPGYDLLVQGEAGLMALNGEAERPPLKFGLAAVDLFTGQYAAQALLAALYKRERTGKGSRVELALFDSGLALTSYYGLEALVQGIDPPRYGNAHPSIVPYGVFDAQDGALVITVGNNAQFQRFCTSVIGRPDLAADPRFATNLERSRNRADLLPELRAELARRTRAELLASLRAAGIPAGEVLGLHEALTSGRAQRAGMVVRSEEGAGAPRYILAPPYRFDGARLPVRALPPELEATNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDA0</accession>
    <name>A8IDA0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2899</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2899"/>
    <dbReference type="EnsemblBacteria" id="BAF88897">
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        <property type="gene ID" value="AZC_2899"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2899"/>
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    <dbReference type="OMA" id="PVQMKVN"/>
    <dbReference type="OrthoDB" id="1755469at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Cation_efflux"/>
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        <property type="entry name" value="Cation_efflux_CTD"/>
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    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
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    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="491" mass="51955" checksum="288BEC70D93D3EE9" modified="2007-12-04" version="1">MAAESRARVDGGTRIGILMTYRASSALIGAPHKNSDAGWKCCSGGACFMRHIRNLRRFAPGVVIPVLALAGAGEASAGGFGLREQSSYYQGTSFAGVAAGGWGLASMYWNPAAISFVPGLQVEGNVSYVAPHASIDVNRATAPITGTNLGTFGVSDIVDNAAIPAMYASYAWERWAVGVSVNAPFGLVTDAPCNWSGRFYGCYSRIYDVNVQGNVAYKVNDWLVIGGGVSVNYMDARLNQAQINGVSTAGPVLGTGQVDGDDVGLGFSLGALFTLAPGTTLGIGYRSSIDLNLTGQVSVYAPTGQNLAMFPANAGLTLPDQVTASFRSQLNPQWTVSGTVEWTNWSSLQKLVVVPQGASISVLDLGWRDGWFFSGGVEYQWDPRLALRTGLAYEISPVTDDVRNPRLPDSNRIWLSVGATYAWTNQLSMDLAYTHIFGQSGSINLSPADPANALRGSLSAQVSDAYVDIVSVALRYKFDAPQPTAVALITK</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3024"/>
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        <property type="gene ID" value="AZC_3024"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0016787">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
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        <location>
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            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
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            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="338" mass="37601" checksum="4B1D808ED2498404" modified="2007-12-04" version="1">MPRNPYHSGPQTSHFDGLRFFNPDHPPTDRALREILRWKMKGRATPWTPAPNRPQAIPEARVPDLSVTIVGHATALIQIEGLNILTDPVWSERASPFSFAGPRRACPPGIAFAHLPPIDIVLLSHNHYDHMDLATLRALQTRDRPLIVTPLGNDAIVRRAVPDARFQTGDWWDVVVLAGGIEITFLPAQHWSARTGRDRRMALWSGFMVRTGSRLVYFAGDTAYGNGRIFREMRTRMGRPDMALIPIGAYEPRWFMKAQHADAREAVQIMEDLEAEQAVGIHWGVFRLTDEGREEPPAMLAASLEARGIAAARFPAGEPGASYGMGGVRPNLVLSCTE</sequence>
</entry>
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    <reference evidence="2 3" key="1">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="8"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="372" mass="39574" checksum="7CC896E21E0788BE" modified="2007-12-04" version="1">MSTQETEVLIIGAGGAGTSAALHLAQRGVACVLLERGLVGGQASGVNYGGVRQQGRHPAELPIARRSMALWHKLKDITGTDAEFTVSGHLKLARTPEEEADLVAYLEVARDNDLPLRFVGRNALHEDYPWLGPKVIAGSLAPEDGAANPRLMVPALAHAARAAGAVIHENTKATRYALDGECFEVTTGTHTFRARWLLNTAGFWGGAVAEAFGEKTPVSALNPNMMVTEPIRHFIEPNLGVVGGNVYLRQIPRGNVIIGGGYGVSDPAVPWSRPKAEETRAAMALAVDLVPELKGISIIRSWTGIDGEMPDHIPVIGPSRTTPRLLHAFGFSGHGFQLGPAVGAILSELVLDGRTDVPLEPFDIGRWTARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEQ0</accession>
    <name>A8IEQ0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Bifunctional cytochrome P450/NADPH--P450 reductase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Cytochrome P450</fullName>
                <ecNumber evidence="11">1.14.14.1</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">NADPH--cytochrome P450 reductase</fullName>
                <ecNumber evidence="11">1.6.2.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">AZC_3520</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NADPH + 2 oxidized [cytochrome P450] = H(+) + NADP(+) + 2 reduced [cytochrome P450]</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>an organic molecule + O2 + reduced [NADPH--hemoprotein reductase] = an alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]</text>
            <dbReference type="Rhea" id="RHEA:17149"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:142491"/>
            <dbReference type="EC" id="1.14.14.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">In the N-terminal section; belongs to the cytochrome P450 family.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.1" evidence="11"/>
    <dbReference type="EC" id="1.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172043.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3520"/>
    <dbReference type="EnsemblBacteria" id="BAF89518">
        <property type="protein sequence ID" value="BAF89518"/>
        <property type="gene ID" value="AZC_3520"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3520"/>
    <dbReference type="eggNOG" id="COG0369">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_7_0_5"/>
    <dbReference type="OMA" id="WKKAHNI"/>
    <dbReference type="OrthoDB" id="520970at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070330">
        <property type="term" value="F:aromatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019344">
        <property type="term" value="P:cysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023206">
        <property type="entry name" value="Bifunctional_P450_P450_red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000209">
        <property type="entry name" value="Bifunctional_P450_P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11 12" id="KW-0349">Heme</keyword>
    <keyword evidence="11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="6 11" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="13">
        <location>
            <begin position="585"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="14">
        <location>
            <begin position="777"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="502"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000209-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAF89518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1158" mass="123325" checksum="E5FB676E43735FD3" modified="2007-12-04" version="1">MSETSTPPALKSVDLGLAAGTVRVGWFPGASREAVLAAVRGAAGLSGETAFHVETADGVTIALDDSVPAGTRLRLVVQGEVPSSAAPALHRPVPGPKPYPVVGNLPELHNAEGLVAAVDALHAKHGEFFAFQVGGKRAYFCSDADIISEMCAAPDVFAKLVEGRGGLGNLAEKSVGSALFTASDNDPLWHQAHRILAPAFGATALKNYYGRIVEVADDLLDHLDRLAPGESFLATDLMTRMTFEAISYAAFNRRYGAIDSPALPAFVEAMNVVLTDAMAEPKRLLPEVFYHEARKTRAAADKIMLEEVETIIAERRFAMAAGAPVPTDLLQVMLTTPDRVTGQKLPDDNIRGQLIVLLIAGHETTSGMLAYALYHLWKYPETMEKLIAEVDEVLGRDFSYKPTYEDVGRLAYTQRVLKEALRLCPPVPMFPRYVTRDATVGNGRYDLKAGERIFVSLSAMQKNPRFWGADALVFRPERFGPEEEKHHHPHAYHPFGMGARSCIGFQFALVEAKMVLARFIQRFTARPKDPHYVLCHKQALTVKPDHLDMLLERRPEVKGRFPVRTEAPKTQGAPLAVAQAGGRPMRVLYGSNMGGCRDIALSLAQQAGARGFAATVAELDEQVGQPWLTDGPVVIVTSTYNGTPPDNAARFAKWLETAPAGVCAGVRHAVLGCGNTQWHQTFQKFPKTIASGLAALGGTALLDEGTADAAGDYEAAVEGWTAALWPALEAAFGGAAGAAVIGSAEAAAEAPAVKVEVVNFAGAATGAAPRTGTRLDQGAQLSRIRVNRELLSPGAQGSTRHIEIPLPAGTSYAAGDHLAVFPVNPPALVAAAAARCGLAPETQVLLTALHPDAASEAGLPFGVPVSVGELLAEHVDLAGPVTRRDLRAWAQAAQCPPDRARIAGWLSDFPSAVAEAKPRMEDLLAQVPSVQLDLAALLTVRPALKPRYYSISSSPLMSPDACALTVGVHQFTTADGVRHDGLCSSYLVSCGEDAPVRVLVKDTGSTFHLPADPAVPLILVGPGTGLAPLRGFIQERHALRAQGRATGPVLLFFGCRDDGDYLYREELEAYRDEGTLSLLAVGFSRRPGTPRTYVQDLLRTHGDAVREQVAAGASILICGNARTMAPDVHAAFLELLGAGAVAELEAGGRYLQDVWASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF25</accession>
    <name>A8IF25_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative amino acid transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_3567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3567"/>
    <dbReference type="EnsemblBacteria" id="BAF89565">
        <property type="protein sequence ID" value="BAF89565"/>
        <property type="gene ID" value="AZC_3567"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3567"/>
    <dbReference type="eggNOG" id="COG0531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007946_5_0_5"/>
    <dbReference type="OMA" id="RDRHLPH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="443"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="518" mass="55073" checksum="2C7B365AF4DDF254" modified="2007-12-04" version="1">MLFHCGGRYEWRPAMSDSSLSKSSSGISYTTVDTAYFEQRKLKRHARVWSLWALGVGAVISGHFSGWNLGIASGGWGGMFIAAVIIAVMYLGLTFSIAEMSAALPHTGAAYSFARTTMGPWGGFVTGLCENVEYVITPAVVVSFIGAYMGSIFGTPTSFQPVYWIFGYIIFVGLNVVGVELSFRVTLVVTLAALACLVAFWVSALPVMDFSRWALNMGVGPDGTAVELPNGGGPFLPFGIGGALAAMPFAVWLFLAIEQLPLAAEESVDPKTDMPRGIIAGMATLIVSAFMILWLNSSVAKGAFGLSTSTEPLLDGFKAIYGTGIAQLLALVAVIGLIASFHTIIYAQGRQIYSLSRAGYFPRGLSVTHGSRKTPHVAMAAGAVVGLAIMLVIWFSLGADAGSAAIGGTLLNMAVFGAMLSYVMQAISFIRMRKNMPHVERPYTSPFGIPGAVATILIALVTIYFQLSDPTYRAGVIGVAIWFAIGIAYFALHGRHKLVLSPEEEFALSGGTSEYKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFW7</accession>
    <name>A8IFW7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3658</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168658.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0127"/>
    <dbReference type="EnsemblBacteria" id="BAF86125">
        <property type="protein sequence ID" value="BAF86125"/>
        <property type="gene ID" value="AZC_0127"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0127"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_5"/>
    <dbReference type="OMA" id="ERWICQP"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="298" mass="32484" checksum="4D82106CB88D4113" modified="2007-12-04" version="1">MEIRTLRAFVEVVRQGGFSNAAKAILATQSTVSKAVRQLEDELGLPLLDRLGHSSRLTAAGEIVYRRAAVMLAEREDLVSELDELRGLTRGVLRLGLPPLGSNILFAPLFALYRQRFPGIEIKLHQHGSRRLEEMVLAGEMDLAGSLLPVAPDFAWQSIHQEPIVALLPASHRLAGAARVDLGDLAADPFLLFQEGFAIDTVLQAACERRGLKPQVAVRSAQADFLVELVAAEVGVTFLPRMIADQRPRPGVARVLLDEPGTDWHMALVWRKGGYLSRAALAWLDLSREVLAANAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH51</accession>
    <name>A8IH51_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_0174</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the four-carbon acid sugar kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0174"/>
    <dbReference type="EnsemblBacteria" id="BAF86172">
        <property type="protein sequence ID" value="BAF86172"/>
        <property type="gene ID" value="AZC_0174"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0174"/>
    <dbReference type="eggNOG" id="COG3395">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029424_0_0_5"/>
    <dbReference type="OMA" id="CGGESAN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037051">
        <property type="entry name" value="4-carb_acid_sugar_kinase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010737">
        <property type="entry name" value="DUF1537"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031475">
        <property type="entry name" value="NBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042213">
        <property type="entry name" value="NBD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17042">
        <property type="entry name" value="NBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07005">
        <property type="entry name" value="SBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SBD_N" evidence="8">
        <location>
            <begin position="29"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="NBD_C" evidence="9">
        <location>
            <begin position="284"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="390" mass="40284" checksum="A9E4087706C472DE" modified="2007-12-04" version="1">MEDNVVGRPQDHTSALDRGTPPMTGLRLVADDLTGALDAAIAFVTPGQHVPVYWNAPPSVAPSRLSIDSGTRETDAASARARVAALLRNITPDADTLFFAKLDSLLRGQAAAEIAAWMEALQPRRCIIAPAFPRQGRVTRGGIQYLCRDGAERPVGADLRATLEAEGHPVHLRRPGEAMPEGVSLWDSETDTDLAQIVAAGRPADGTTLWCGSGGLAAALTGHPSGIDVAPRTLPRPILGLFGTNHPVTVAQLAACGDAVLALSADGPDNAAALGNKLAADGVALARLALPEGTPRPVAAARIAEAFSSLVAQLDPPGTLIVSGGETLRSLCAALGAERLDLYGQIESGVPCSILRGGRFDGVHIISKSGAFGAPSLLRRLTETSEGDDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH90</accession>
    <name>A8IH90_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ordered locus">AZC_0190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0190"/>
    <dbReference type="EnsemblBacteria" id="BAF86188">
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    <dbReference type="KEGG" id="azc:AZC_0190"/>
    <dbReference type="eggNOG" id="COG0282">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_020352_0_0_5"/>
    <dbReference type="OMA" id="SMRRRIC"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
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        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Ac/propionate_kinase"/>
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        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
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    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
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        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="207"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="282"/>
            <end position="284"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="327"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="393" mass="41830" checksum="1DEE91FF93C93C8B" modified="2007-12-04" version="1">MTDAVLVVNSGSTSLKFAAYAAGADAVPPLLCRGVVDSMTSDPHFIAKAPDGTPIDAHEWGEGQNLGHGRALSFIIQWLEQHEANIKVVAAGHRVVLGGTRFEGPVRITPEVLDYLDGLSAMEPSHQAYNVRGARELAQDFPGLPQVAMFDTSFHRSMPEVAQVYALPAELRDTGVRHWGYHGISYDYISRQVPKYVPDARRVIVAHLGGGASMCAMLDGRSMETTMAFAGLTGLPMATRSGDVPADVLFYLLKTQGHDVASLEKLLYGKSGLLGLSGVTGDMRQLQDSKDPAAVLAVDAFVYAMTKFTGAYAAVLGGLDALVFTAGIGENSPIVRAALCARLEWLGVKLDPAANTANGPRISATDSRVGVFVIPTNEELMIAQHTLALLQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHC0</accession>
    <name>A8IHC0_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">L-PSP endoribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168733.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0202"/>
    <dbReference type="EnsemblBacteria" id="BAF86200">
        <property type="protein sequence ID" value="BAF86200"/>
        <property type="gene ID" value="AZC_0202"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0202"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100715_4_5_5"/>
    <dbReference type="OMA" id="EWLMEID"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="137" mass="15321" checksum="072485E56A3952E5" modified="2007-12-04" version="1">MIHRRIRPFNTAKTYPEQRLDNDLAQAVVARGTTIFLRGQCPQDLDTAEDVGIGDPVAQTHKVMQNIRQLVEESGGTMEHVCKLVVYLTDVRHREAVYRTMGEYIRGVHPVCTGLVVVALARPSWLVEIDATAVIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHR3</accession>
    <name>A8IHR3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3311</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171834.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3311"/>
    <dbReference type="EnsemblBacteria" id="BAF89309">
        <property type="protein sequence ID" value="BAF89309"/>
        <property type="gene ID" value="AZC_3311"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3311"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2566486_0_0_5"/>
    <dbReference type="OMA" id="FHEQTPP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="81" mass="8845" checksum="D0A2FADCF96C76B0" modified="2007-12-04" version="1">MPVPVSIAGGGASRLKHSGGARQRVVIAHRLSTVRTLDRLLVFDHGRIAEQGRPADLLRLDGGLYRRLHERQTLDLGLAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8II52</accession>
    <name>A8II52_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3363"/>
    <dbReference type="EnsemblBacteria" id="BAF89361">
        <property type="protein sequence ID" value="BAF89361"/>
        <property type="gene ID" value="AZC_3363"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3363"/>
    <dbReference type="eggNOG" id="COG0489">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024839_0_0_5"/>
    <dbReference type="OMA" id="ADVWGYS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
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        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
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        <ligand>
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        <source>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01883"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89361.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Iki T."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3365"/>
    <dbReference type="EnsemblBacteria" id="BAF89363">
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        <property type="gene ID" value="AZC_3365"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3365"/>
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    </dbReference>
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        <property type="entry name" value="GST_C"/>
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        <property type="entry name" value="Gtt2-like_C"/>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="19"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="106"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
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            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="225" mass="25415" checksum="8BE8BB548C9C6021" modified="2007-12-04" version="1">MTPPPLPWSLGIQNTRRRHAMLLYLSARSPNPRRVQFFLAEKGIEVPVEMVDLAAKAHWSEDFRKISPRRTVPVLVLDDGTAVSETIAICRYFEAVQPEPNLFGRDAREIAVVEMWQRRAEIELMQAVQFAFRHVHPALAEREVPQVKEWGEANKTKVLDFLTFLDGELATRAYLAGDRFTVADITAIVAIDFMKVARITAPEELVNLARWRAEVSARPAAKAGA</sequence>
</entry>
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                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    <sequence length="603" mass="64315" checksum="6578D0D4CBFB5BAC" modified="2007-12-04" version="1">MSRPLPILPALLLAAALLVLPALAQAAPRLTLSATPDTLISTGTVEVVIALTEGDGREPPNLTPLTRDFDIVGQGRRSRTEVVDGRRVPVNEWLVTLAPKRTGRLIIPAISLAGLSTAPVAVNVVPSTGGALTDERTLFVRLEAGDVQPFVQSDVPVTVRVYDRLGLRGGGISRISADGASFTPQGEQRAYYRTIGRYRYQVIEQSYLMRPQRSGTIEVPPVTLEAKVPAYTGGQLPPDIAGALGRPQPPNPWDTNFPSVRDLTVQSNPLTVTVRERPADAKGWFLPARSLTISSEWAKPPKDVKVGEVLTRTIRVEAEGAGPNQLPPLTLAEVPGVRQYEEQSRTESAPVRGAPGALLTKTVSVVPTRSGTFTLPAIELGWWNTATQKQETATLPAETFTVAADPRAPQTAAGPVAAATSGTGGSARTPPPAVASDTSLLHSALGLWSVWRTWFMLAAEIALFCLCVAVVMAGLRRLERWRRGRRIAQAAEAGDPANASIATLAQAEAALEAGCKARNAALAHRALMAWLRLSATGTQAPVPVTPALAQALTAVQDALYGTAPRPFDAKRLRAAFHAEQRARRKGARQERGARLAPLYPTTR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Akiba N."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A24 family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_0281"/>
    <dbReference type="EnsemblBacteria" id="BAF86279">
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        <property type="project" value="InterPro"/>
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    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="3">
        <location>
            <begin position="15"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86279.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="155" mass="15765" checksum="F1B6F587847DBC91" modified="2007-12-04" version="1">MSPVLLAEAFASILVPVALVAALASDLSRRTIPNIVVLALLLGFAALAFLGYVDDLPLRLVLAGAVLCVGFALFSEDVIGAGDAKLAAATALWLDPTQFPLYVLLCGAMGALLVAAATVARQQGWGGRLARGLPYGVALATAGLALFPYSSLALA</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168836.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0305"/>
    <dbReference type="EnsemblBacteria" id="BAF86303">
        <property type="protein sequence ID" value="BAF86303"/>
        <property type="gene ID" value="AZC_0305"/>
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    <dbReference type="eggNOG" id="COG1028">
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    </dbReference>
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        <property type="entry name" value="AcAcCoA_reduct"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="240" mass="25264" checksum="80FD20F072DE1573" modified="2007-12-04" version="1">MSRVALVTGGTRGIGEAISIALKDKGYKVAANYAGNDAAAQAFHEKTGIPVFKWDVSDFEACKAGIAKVEADVGPVEVLVNNAGITRDATLHRMTLEQWNAVINTNLNSAFNMCRNVIEGMRARKFGRIVCISSINGQKGQFGQTNYSAAKAGEIGFVKALAQESAALGITVNAIAPGYIATEMVRAVPEDVLKKIISTIPVGRLGEPEDIARAVAFLVADDAGFITGSTLTANGAQYIT</sequence>
</entry>
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    <accession>A8IKC5</accession>
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        <name evidence="2" type="ordered locus">AZC_3889</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3889"/>
    <dbReference type="EnsemblBacteria" id="BAF89887">
        <property type="protein sequence ID" value="BAF89887"/>
        <property type="gene ID" value="AZC_3889"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3889"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Peripla_BP_I"/>
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        <property type="entry name" value="Urea_ABC_transptr_substrate-bd"/>
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        <property type="entry name" value="SSF53822"/>
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        <property type="entry name" value="urea_ABC_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721732" evidence="1">
        <location>
            <begin position="28"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="412" mass="45638" checksum="2B0F3BFCBACD2D56" modified="2007-12-04" version="1">MKKSVLRGLRAAAFSGTLVLGSGAAFAADPVKIGVLEDQSGDFAVATIGKVHAIQLAADEINKAGGIAGRPVELVIYDTQSDNTRYQEFMRRVLQRDKVDVVFAGFSSASREAYRPIVDQLNGFAFYNNQYEGGVCDGHMIVTGAVPEQQFSTLIPWMMEKYGKKVYTLAADYNFGQISAEWVRQIVKQNGGEMVGEDFIPLGVSQFSQNIQNIQKAKPDFVVTLLVGTAQASYYEQAAAANVNLPMASSVNVGQGYEHKRFKPPSLKDMYVTTNYIEEIDSPKSKEFVAKFKAKFPNEPYVNQEAENSYLAVYLYKQMVERAKSTKRDDIRKVIAQGDVCMDAPEGKVCIDPKSQHMSHTIYLAKVGADHSITFPKVWEDIKPYWLGEAGCDLTKKDPMAQYTPSNPPPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL23</accession>
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            <fullName evidence="2">Pyrroline-5-carboxylate reductase</fullName>
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        <alternativeName>
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        <name evidence="2" type="primary">proC</name>
        <name evidence="5" type="ordered locus">AZC_3979</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172499.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3979"/>
    <dbReference type="EnsemblBacteria" id="BAF89977">
        <property type="protein sequence ID" value="BAF89977"/>
        <property type="gene ID" value="AZC_3979"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3979"/>
    <dbReference type="eggNOG" id="COG0345">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042344_0_2_5"/>
    <dbReference type="OMA" id="VVRVMTN"/>
    <dbReference type="OrthoDB" id="1349288at2"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="3">
        <location>
            <begin position="13"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="4">
        <location>
            <begin position="170"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="278" mass="27594" checksum="9C9FADF9663D27AF" modified="2007-12-04" version="1">MSLEVLKQLDGPIVLVGAGKMGGALLEGWLGLGIEPARLVVLDPNLNPEAAKALADKGVSANPAYDAIPHAAVLILAVKPQVAPAVIASIRGIVGPKSVVVSIMAGRTIGFMQEALPRGAAIVRTIPNTPAAIGKGITVAVANAAVSPEARAATSALLGTVGPVEWVESESLIDAATAVSGSGPAYVFLLAEALAKAGAAAGLPADLADRLARATVSGAGALLEQSGIDPAILRQNVTSPGGTTAAALAVLMDEAKGFGPLLTQAVAEATHRSRELAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILA4</accession>
    <name>A8ILA4_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4008</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF86580.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="588" mass="60680" checksum="B6F8CEE83AFAAFC2" modified="2007-12-04" version="1">MSIQFPAPHSRFVDGSVAEGTSARPRMDTAGAHAAPARRRRPRPAQNLESRGGALLQLVASLLFIGQAALIARAVGTMSSAITVPALLGPAAGILALGVVRAILEALGARLCHRQARAALGRLRSEVAAAVAARSPLDRNRPVAGAVASALAEQAEAVVPYLSRFKPARLRASVVPFVMLAVVLPLSWAAALVMLVALPLIPVFMALIGWRAQAASEAHLKEMGSMNGFLLDRLRGLATIRALGAVDTTALRLRASAETLKDRTMAVLRIAFLSSAVLELFSALGVAMVAVYVGFHLLGTLEFGTWGVPLNLSDGLFILILAPAFFEPMRDLSAVWHDRAAGEAAFAALKLLTANGLPLPGANMAHPVPAAAAPAPDVVFDTVSFTHAEGRAPFAAFSLTVPAGGRVALLGPSGAGKSTLLALAAGLAPVHTGSVRIGGLPLTAETAAELRSGMAWIGQRPHFFAGSLAANVQMGRPDIGPEAVEEALAFATLDRAVRGRSADDGLGEGGAGLSGGELVRLAIARAAVDPRVQLVLADEPTAHLDAATAAEVTEALLTLATGRTLIVATHDPVLAARLDTVVQLEPRP</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="entry name" value="Tautomerase/MIF_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Tautomerase_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="BAF89696.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="144" mass="15532" checksum="6DDCE2671FC4751B" modified="2007-12-04" version="1">MPASTTAEPEFPMPFTRISLLAGHPPAYLEALSDSLHAALVESFEVPAADRFQIFHQHQPGELVFDRDYGGGPRSAGFVLFHITTGRARSPAVKRAFYRHLVANLAASPGVRPEDVMVVLSASQLEDWSFANGESAGAPEEEAA</sequence>
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    <accession>A8IN80</accession>
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            <fullName evidence="6">LapA_dom domain-containing protein</fullName>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="113" mass="11945" checksum="433E2D2B54EB7F42" modified="2007-12-04" version="1">MSSAPVGRLLAVIIGLPVSVAIVALAVANRRPVTLSLDPFSPDTPVISVTVPLFAVIFGALILGLVIGGLVTWARQGRYRRAARRARRDLAAAEVRHEAQMATATALPAVVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8INH5</accession>
    <name>A8INH5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydroxy-acid dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3752</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172275.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3752"/>
    <dbReference type="EnsemblBacteria" id="BAF89750">
        <property type="protein sequence ID" value="BAF89750"/>
        <property type="gene ID" value="AZC_3752"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3752"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014271_3_1_5"/>
    <dbReference type="OMA" id="MLNGWHE"/>
    <dbReference type="OrthoDB" id="193579at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="604" mass="64805" checksum="3E50C5D9E076E6EB" modified="2007-12-04" version="1">MVGQGDQPENHGRKLRSQLWFDNPDNPGMTALYLERYLNFGLTREELQSGKPIIGIAQTGSDLSPCNRHHLDLAKRVREGIAAAGGIPFEFPVHPIQETGKRPTAALDRNLAYLGLVEVLYGYPLDGVVLTTGCDKTTPACIMAAATVNIPAIVLSGGPMLNGWWNGERTGSGTVVWKARAQHAAGEIDYDTFMEIVASSAPSVGHCNTMGTASTMNGLAEALGMSLPGCAAIPAPYRERGQISYETGKRIVDMVWEDLKPSDILTREAFENAIRVNSAIGGSTNAPIHLNAIARHVGVSLTVDDWQAVGHKIPLLVNLQPAGEYLGEEFHRAGGIPAVVAELIQAGQIHEGALTVNGRSIGENCRGKFSWDRDVIRAYDAPMKADAGFIVLRGNLFENAIMKTSVISEEFRARFLSDPKDPNAFEGPAVVFEGPEDYHHRIDDPALGIDEHTLLFIRGTGPIGYPGGAEVVNMQPPAALIKRGVNALPCIGDGRQSGTSGSPSILNASPEAAAGGGLALLKTGDRVRIDLEKGTADILISDEELAQRRAALEANGGFPIPQSQTPWQEIQRSMVAQFDEGMVLKPAVKYQRVAQTMGVPRDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8INM8</accession>
    <name>A8INM8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CMD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3769</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172292.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3769"/>
    <dbReference type="EnsemblBacteria" id="BAF89767">
        <property type="protein sequence ID" value="BAF89767"/>
        <property type="gene ID" value="AZC_3769"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3769"/>
    <dbReference type="eggNOG" id="COG2128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082760_4_1_5"/>
    <dbReference type="OMA" id="QAKTSDY"/>
    <dbReference type="OrthoDB" id="1925754at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010195">
        <property type="entry name" value="Uncharacterised_peroxidase-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01926">
        <property type="entry name" value="peroxid_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="55"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="191" mass="20919" checksum="DFDFAEC90CD10A8E" modified="2007-12-04" version="1">MSEVVHTFTTKVPRWRPYVTPVRLEEATEEQREAMKITPSNTKVSDYVLTLAHDPESLAVRSPLFNAIMYGDDGLSRAERELGAVGASVVNRCVYCAAVHASRYNQLAKAPEVIKAIFAAETKAELEPRNQAIFDFAVAVSNTPPEAAADHIAALREQGLTDLEQVDLILSAAIFGWANRLMHTLGEPVAT</sequence>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3793"/>
    <dbReference type="EnsemblBacteria" id="BAF89791">
        <property type="protein sequence ID" value="BAF89791"/>
        <property type="gene ID" value="AZC_3793"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3793"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_15_9_5"/>
    <dbReference type="OMA" id="IISAHIW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="108" mass="11943" checksum="A09BC97DC0597937" modified="2007-12-04" version="1">MGQVLHRCATTTDAVRRAIQHSQESLRARAKRDGINQKTAPRWKQRNSVADLPTGPKAPKSTVLSGEEEAIIVAFRHHTHPSRISGASPHDMTRSRPTSWLPSPPPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPJ6</accession>
    <name>A8IPJ6_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2 5">Flagellar P-ring protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Basal body P-ring protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">flgI</name>
        <name evidence="6" type="ordered locus">AZC_0632</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="1 5">Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Periplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the FlgI family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169163.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0632"/>
    <dbReference type="EnsemblBacteria" id="BAF86630">
        <property type="protein sequence ID" value="BAF86630"/>
        <property type="gene ID" value="AZC_0632"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="6" id="KW-0969">Cilium</keyword>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="20"/>
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    </feature>
    <feature type="chain" id="PRO_5009007225" description="Flagellar P-ring protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002591"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="366" mass="38471" checksum="5ECC47DD82383543" modified="2007-12-04" version="1" precursor="true">MISRFLIAALVVLLAGPALALTRIKDISSVQGVRDNQLIGYGLVMGLQGTGDTLRNSPFTEQALQAMLDRMGINVVGSPLRARNTAAVMVTANLPAFAAIGSRVDVTVSSIGDATSLKGGTLLITQLNNTDGLTYAVAQGQLAVSGFSVQGQAETLTQGVPTSGRIPNGALVERQIPGQLRDLNEYLIDLTNPDFKTASLMADAINAYTQARYGRPLARERDLRTVVVQRPPQANPARFLAEIGELGIEVDTPAKVVVDQRTGTVVIGRNVQVSTVAVTQGSVTVRVTETPVVSQPNPFASGSTVVVPRTDIQADEAGGHLAVVRGTDLQTLVRGLNRLGLKPSDIIAILQAIKTSGALQAELVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPL3</accession>
    <name>A8IPL3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar basal-body rod protein FlgF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_0645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169176.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0645"/>
    <dbReference type="EnsemblBacteria" id="BAF86643">
        <property type="protein sequence ID" value="BAF86643"/>
        <property type="gene ID" value="AZC_0645"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0645"/>
    <dbReference type="eggNOG" id="COG4786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013687_0_0_5"/>
    <dbReference type="OMA" id="MQSGLYV"/>
    <dbReference type="OrthoDB" id="947161at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012836">
        <property type="entry name" value="FlgF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02490">
        <property type="entry name" value="flgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0282">Flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="5">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="6">
        <location>
            <begin position="179"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="240" mass="25751" checksum="5820D4A99FE4247E" modified="2007-12-04" version="1">MSNGLYVALSGQMATEKRMATIANNVANMNTPGYRAEEIKFSSIMAEQGAKDIKFASTGESYTSRRAGPITYTNSPYDVAVQGKGWFSVKTPDGVAYTRDGRFNVTADGMLVSVNNYPVLDQGGTAVMIQPNQGELKITADGTIIQGTNPVGTLGLFEIPLDAKLKRYDNSAVIPDKAATPVTDYNSNAIRQGYVEGSNVDPVMEMTRLIMVQRAFESAAQAISQQETSGTDSIRALGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPM9</accession>
    <name>A8IPM9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type III secretion system inner membrane R protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0655</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0655"/>
    <dbReference type="EnsemblBacteria" id="BAF86653">
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        <property type="gene ID" value="AZC_0655"/>
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    <dbReference type="KEGG" id="azc:AZC_0655"/>
    <dbReference type="eggNOG" id="COG1684">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_063626_3_1_5"/>
    <dbReference type="OMA" id="PMQVRLF"/>
    <dbReference type="OrthoDB" id="1942709at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="54"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="249" mass="26905" checksum="210F5EA1111FDBA0" modified="2007-12-04" version="1">MIPLDVSILSAFLVFCRIGSCIMMMPGLSGYRLPVRVRLLLAVAVSLAILPLMYDDLVNFIRNANSAQLLLSIGTEMATGAIIGTLARIFYLMLQMMLVAIAQFIGLSSPMGLPEDGEVLPSLATLMILAATTMMFLTDQHYEMLRGLIASYRQIPVGVGFGGRGALIQASDQLSAALMIAMRLASPFLIYSLIINFAVGLINKLVPQIPVYFISAPFILLGGLILLYGLSDQMLTAFSAAFNLFLRTG</sequence>
</entry>
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    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169307.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0776"/>
    <dbReference type="EnsemblBacteria" id="BAF86774">
        <property type="protein sequence ID" value="BAF86774"/>
        <property type="gene ID" value="AZC_0776"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0776"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_3_5"/>
    <dbReference type="OMA" id="KRERPWI"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="69"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="504" mass="55519" checksum="F01016E7A4492600" modified="2007-12-04" version="1">MWKQFFAALTIVGGLTGAVGAGAQAQTLRFGLMDDPDALDPTLSRNYTTRMVFAALCDKLVDIDAKLNIIPQLASEWSWSADQKTLTMKIRPGLTFHDGEKLDAEAVKFNLERHQKMPGSQRRSELAALDTVEVVDPVTVRLHLKAPSAPFLSQLTDRAGMMVSPKAAQALGDKFATAPVCAGPFKFVERVAQDHILLEKFDGYWNKDNIFLQKVDFRTIPDSTVRLTNLRSGQLDLLERLAPTDLPEVRSQGKLKVGTGYELGFQSIIFNTAKADSVIGGDARVRKAFELSIDREALSQVVFNGEYLPGNQWVSPKNPFYVSAFPIPKRDVAKAKALLKDAGVKTPVPVNLIVYSTNEAAQVGQVVQAMTKESGFEVKLVTTDIGTALNAADQGNFEAFLYAWSGRPDPDGNTYNFLACKAPLNYTRFCNEKAQAALDAERATSDPAARAAAWKNLAEVVLTEDPLIYLYHRKLMWAYTPKLKGFTEADYPDGLVRFTGLKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQK7</accession>
    <name>A8HQK7_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">Ferredoxin</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="primary">fdxN</name>
        <name evidence="5" type="ordered locus">AZC_1043</name>
    </gene>
    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169660.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1129"/>
    <dbReference type="EnsemblBacteria" id="BAF87127">
        <property type="protein sequence ID" value="BAF87127"/>
        <property type="gene ID" value="AZC_1129"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1129"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_5"/>
    <dbReference type="OMA" id="SYPRRVW"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="223" mass="24893" checksum="CB546D157B69A5D9" modified="2007-12-04" version="1">MRLLVIEDDPDLNRQLVNALGEAGYAVDTAFDGEEGHFLGDSEPYDAVVLDIGLPKLDGISVLEHWRRAGRRMPVLILTARDRWSDKVQGFDAGADDYVAKPFHMEEVLARLRALLRRASGHASSELTCGPVRLDTRSGRVSVGGSPVKLTSHEYRLLSYLMHHAGRVVSRAELVEHLYEQDFDRDSNTIEVFVGRLRKKIDCDVIQTVRGLGYLLAAPETAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRA0</accession>
    <name>A8HRA0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">D-alanyl-D-alanine dipeptidase</fullName>
            <shortName evidence="3 4">D-Ala-D-Ala dipeptidase</shortName>
            <ecNumber evidence="3 4">3.4.13.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ddpX</name>
        <name evidence="5" type="ordered locus">AZC_1150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>D-alanyl-D-alanine + H2O = 2 D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20661"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="EC" id="3.4.13.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase M15D family.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.22" evidence="3 4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1150"/>
    <dbReference type="MEROPS" id="M15.011"/>
    <dbReference type="EnsemblBacteria" id="BAF87148">
        <property type="protein sequence ID" value="BAF87148"/>
        <property type="gene ID" value="AZC_1150"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1150"/>
    <dbReference type="eggNOG" id="COG2173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060744_0_1_5"/>
    <dbReference type="OMA" id="IRTEWWH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01924">
        <property type="entry name" value="A_A_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000755">
        <property type="entry name" value="A_A_dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01427">
        <property type="entry name" value="Peptidase_M15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026671">
        <property type="entry name" value="AA_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR026671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="226" mass="24693" checksum="24672A1F63EB0E5B" modified="2007-12-04" version="1">MDTGSRTGSMERGGASMSVSAEPVLPALFVDVPAVVPNVIVDLRYAGPNNFVGVRVDGYEAERALLTRPAAEAAARVAEGLARQGLVLKLLDCYRPTRAVAHFARWAADTNDLGTKADFYPDHDKPELFDLGYIAGRSSHSRGSTLDLTLAHASDGTELDMGTPFDLFSERSWPASLAVTDAQRDNRRLLAAAMTDAGFEPFLMEWWHFTLKGEPFPDTYFDAPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRQ5</accession>
    <name>A8HRQ5_AZOC5</name>
    <protein>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="5 6" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="255"/>
        </location>
    </feature>
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        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="255" mass="28308" checksum="F4500CB14720BFCF" modified="2007-12-04" version="1">MNAQVISDQMAPDFLLAVEGLTVSFDGFKAVDDLSFYVDENEIRVIIGPNGAGKTTVLDLICGRTKATSGSVKFKNTELTKMKEYEIVRAGVGRKFQNPSIYEDLTVFENLEISYPKGRGVVGALAFKRDGAVKARVQDIAETIFLADLLNQRAEYLSHGQKQWLEIGMLLIQDPELLMLDEPVAGMSVAERKKTAELLNRIIKDRSVIVIEHDMKFVEDIAHKVTVLHQGKILSEGTMAKVQADPKVVEVYLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF90129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF90129">
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    <dbReference type="eggNOG" id="COG0765">
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        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="TM_PBP2"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
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    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="20"/>
            <end position="45"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="217"/>
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    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="21"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50928"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF90129.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UbiH/COQ6 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172749.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4229"/>
    <dbReference type="EnsemblBacteria" id="BAF90227">
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        <property type="gene ID" value="AZC_4229"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4229"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_8_1_5"/>
    <dbReference type="OMA" id="AHGFNFG"/>
    <dbReference type="OrthoDB" id="867226at2"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018168">
        <property type="entry name" value="Ubi_Hdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010971">
        <property type="entry name" value="UbiH/COQ6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01988">
        <property type="entry name" value="Ubi-OHases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01304">
        <property type="entry name" value="UBIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="8">
        <location>
            <begin position="10"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="411" mass="43985" checksum="D8C5D5084876FDAA" modified="2007-12-04" version="1">MGKDARPEAADVVIAGGGLAGLSLALALKDGLGPDAAITVYDPGFGKPLTGDRRCSAIAAGARRLLTVLGVWDEVAPEAQPMKTMVVTDSRTRDVARPVFLTFDGDVEPGEPFAYMVPNAVLQQALTDAAGRAGIDMRAAPVSDFATDRSGVTVTGGDGAVLRASLLVACDGSKSRLRSLAGITSTSWAYGQSAITFTVEHERPHLGEAVEHFLPPGPFATLPLPGNRASIVWTERTEDAKRYAELPDYRFQEELEQRFGHKLGWVKLETKPQVYPLGFAMARSFIGERFALVGDAAHLIHPIAGQGLNMGLRDVAALAEAVTDAARVGLDFASPQVLERYQRWRRFDTLAMGVATDTLNKLFSNQSDALRIIRDVGLGLVDRMPKLKGLFIRDAAGLTGAVPKLLRGQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTC6</accession>
    <name>A8HTC6_AZOC5</name>
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        <submittedName>
            <fullName evidence="15">Chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">AZC_0821</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A8HTC6"/>
    <dbReference type="STRING" id="438753.AZC_0821"/>
    <dbReference type="EnsemblBacteria" id="BAF86819">
        <property type="protein sequence ID" value="BAF86819"/>
        <property type="gene ID" value="AZC_0821"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0821"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_12_5"/>
    <dbReference type="OMA" id="RDQTYMM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="14">
        <location>
            <begin position="386"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="12">
        <location>
            <begin position="479"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="13">
        <location>
            <begin position="631"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="484"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="433"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAF86819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="735" mass="76108" checksum="F5E4DD83E0F159E5" modified="2007-12-04" version="1">MRRGLFGLRKASRVLVGRRGSSMRISDLPIRTKLVGFAGALFGIGLMVVGAIGLYTMTSAVQLDAERRGQALAKDSARTIAAQVEEAALTARAAATAIEGFIGEKGGDRDRLGFVLSGLVAENPALAGMTLAFESGKLDGQDKDFAGHALADSTGRFSARFYRDAGGSVAREAVNVSQDGAAQRWYPSAVQQGRAVATPAYAAVFGGRPVKVVTVAVPVRRAGTPIGVVAVDLPLERIARTVADLKPFGTGVAAVVGSDGNWLAGAEAERVGGAVTDPALTALVKDAAGGKPVQRIIYTDEGKTFCGVCTTLIRLAFTLTGTYDSATFYAFASQVQIAGVGERWTLILTVPKADALQTVTDARNMMGGIAAIVLVLVLVLVWVGAQLLTQPITDITDKMRALAGDDTSIRLDGLERKDEIGDMARAVEVFRQNAIERHELEAARAEAQAAQEARQKAIDSLIARFREAAAAMIGEATTASTDLEAVSSQLSHSATESKERAHSASEASARASADMQSVAAAAEQMASSIGEISRQVASTSEMIGHAAADARSTNEKIASLANAANRIGDVVSLIEAIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKELAAQTSKATSEIISQVSAIQAETQHAVEAIRTISGTIENVDSFASSIAAAVEQQSATTNQIGNNIDSAANGTGAVADDIQQLNSAVQGTDASASRVLNASRSVKEATSRLQSEIDGFLRSVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
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    <name>A8HTW2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC-type molybdate transport system periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169410.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0879"/>
    <dbReference type="EnsemblBacteria" id="BAF86877">
        <property type="protein sequence ID" value="BAF86877"/>
        <property type="gene ID" value="AZC_0879"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0879"/>
    <dbReference type="eggNOG" id="COG0725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079071_1_0_5"/>
    <dbReference type="OMA" id="RTTIHWA"/>
    <dbReference type="OrthoDB" id="1506401at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723932" evidence="1">
        <location>
            <begin position="37"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="266" mass="26686" checksum="DE3D7353FA20A5F4" modified="2007-12-04" version="1">MPATPPLRTFARRASALCLPALALGLALLSGHPAAAAELKVLTTGAFKPVVADTAKRFSQSTGTQVTVDNDTAGALVKRVEGGENFDVLILTPAALAALQKSERVGLGTVVPLAKVGIGVAVKAGAPKPDVSTPDAFKAALLAARKVAMIDPASGGSSGIYLTGLFEKMGIADEVKAKAVLVPGGLVATRVVSGEADLAIHQVSEILAVPGAELVAPLPAAIQNYTVYAGALAPNPSNADTAASFLALLAAPDMAPMLAAKGMEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTX2</accession>
    <name>A8HTX2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">nusG</name>
        <name evidence="9" type="ordered locus">AZC_0882</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0882"/>
    <dbReference type="EnsemblBacteria" id="BAF86880">
        <property type="protein sequence ID" value="BAF86880"/>
        <property type="gene ID" value="AZC_0882"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0882"/>
    <dbReference type="eggNOG" id="COG0250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067287_1_0_5"/>
    <dbReference type="OMA" id="DGPFNGF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015869">
        <property type="entry name" value="Transcrpt_antiterm_NusG_bac_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01014">
        <property type="entry name" value="NUSG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="6"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="180" mass="20490" checksum="ED40C7A1DD438079" modified="2007-12-04" version="1">MRGAMAKRWYIVHAYSNFEKKVADSIREQAEQRNLTDLFEQILVPTEKVVEVRRGRKVDTERKFFPGYVLVKMDLTDEAFHLIKNTPKVTGFLGADNKPMPISENEAMRILQQVQEGIERPKPSISYEVGETVKVSDGPFATFNGIVEEVDESRSRLKVAVSIFGRATPVELEFGQVEKV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTX8</accession>
    <name>RL1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplA</name>
        <name type="ordered locus">AZC_0884</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169415.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HTX8"/>
    <dbReference type="SMR" id="A8HTX8"/>
    <dbReference type="STRING" id="438753.AZC_0884"/>
    <dbReference type="EnsemblBacteria" id="BAF86882">
        <property type="protein sequence ID" value="BAF86882"/>
        <property type="gene ID" value="AZC_0884"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0884"/>
    <dbReference type="eggNOG" id="COG0081">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062853_0_0_5"/>
    <dbReference type="OMA" id="GWTDVDV"/>
    <dbReference type="OrthoDB" id="1671455at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0810">Translation regulation</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000073216" description="50S ribosomal protein L1">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <sequence length="232" mass="24076" checksum="D62FA43872830E99" modified="2007-12-04" version="1">MAHQGKRVRAANEGIDRLKLYPLDEALALLKARTTAKFDETIEVAINLGVDPRHADQMVRGVCNLPNGSGRTVRVAVFARGAKADEAKAAGADIVGAEDLLETIQGGTIEFDRCIATPDLMPLVGRLGKVLGPRGLMPNPKVGTVTMDVKGAVAAAKGGAVEFRVEKAGIIHGGIGKASFPADKLAENIRAFVDAVVKAKPTGAKGTYVQRVAVSSTMGPGIKVDTASVVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUI7</accession>
    <name>A8HUI7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ALGX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0951</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; alginate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169482.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0951"/>
    <dbReference type="EnsemblBacteria" id="BAF86949">
        <property type="protein sequence ID" value="BAF86949"/>
        <property type="gene ID" value="AZC_0951"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0951"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_711619_0_0_5"/>
    <dbReference type="OMA" id="NTLGKQY"/>
    <dbReference type="OrthoDB" id="1439364at2"/>
    <dbReference type="UniPathway" id="UPA00286"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031811">
        <property type="entry name" value="ALGX/ALGJ_SGNH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16822">
        <property type="entry name" value="ALGX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0016">Alginate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ALGX" evidence="4">
        <location>
            <begin position="86"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="368" mass="41007" checksum="EEFE67FA6A9C8DA0" modified="2007-12-04" version="1">MPLLFAYRRWWCFAFIGLLLLPTLGLVMPDLKAPIRTVQTVPPAWWIQATERLDPYINNNYGFRGLFMGAHAAYSKFMKSTRERPVLIGQKGQIFYTGEKALDQSLGRIFRTDQVERLVRVTDRMRDVLKARGITFAMVVPPNGQSVMPDLLPAWAQTEQKRPTEYDSVAATLPARGTAFADLRPELTAAREEGPVYRRTDTHWNNRGAVLGFNAAMRAAGRPELQVPESEALGPLTPTATGDLARYLGETSETGDLDYPPKGPMVQPANLKPLPGLMPATRGNDPFEGYAYETGHAGPRILVIGDSFSQSFWPGLLARNASAFGWTHHRNCRFEWSVIDRFKPDIVIYAPVERAITCLGSPAGLDMK</sequence>
</entry>
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        <name evidence="4" type="ordered locus">AZC_0978</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0978"/>
    <dbReference type="EnsemblBacteria" id="BAF86976">
        <property type="protein sequence ID" value="BAF86976"/>
        <property type="gene ID" value="AZC_0978"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0978"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_065316_0_0_5"/>
    <dbReference type="OMA" id="NPILANR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="40"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="262" mass="27594" checksum="F4EE5236A326FA4E" modified="2007-12-04" version="1">MRAGSRPAGRASEPAGRNRMTEHTGEAARLPSGAVFPQERIRAALNFGNVLFTTQDDAGAPVGLGPDLMHALADHFGLGLDIRSYAQPPDVVADANTDAWDVTILAIEPAREAFVAFAAPMTRIEATCVVDAAYTETSLAELDRPGFRLAAMDRSGYELYLSRTLKAATLVKTASFAESIARFNAGEADAVAGLATMLAGRLPDMPRGRLMPHSFQTIHHGFAVPHALAPLLPAINAFVAQSAASVITQAVSRHGIVGLTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV61</accession>
    <name>A8HV61_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Putative response regulator</fullName>
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    <gene>
        <name evidence="2" type="ordered locus">AZC_4275</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4275"/>
    <dbReference type="EnsemblBacteria" id="BAF90273">
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="LytTR_DNA-bd_dom"/>
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    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
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    <proteinExistence type="predicted"/>
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        <location>
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            <end position="253"/>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
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        </source>
    </evidence>
    <sequence length="253" mass="27695" checksum="6E72D153F89B941F" modified="2007-12-04" version="1">MTKTSRSEGGTTEAELAALPFEYRLQRTPVGVIILDAQQRIRAANPQARLLLARRSEPLIGTDILSLHPEAARAKVAFLLQSARDSAEGAASLVVTTAMGSLVAKVTRLEDTADGGFCMMFHALGARTMGEPDLPPEAEAPRLLKLPVMRGTGDVTGLIDVEDVVFLSAEGHYARAVTRDVTAFCPRALADLEPRLDPALFLRVHRRHMVNIRHVRAAERSDGRWWLRMADAGSSRLPVSRARVADMRRMLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVH3</accession>
    <name>A8HVH3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">AZC_4315</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172835.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4315"/>
    <dbReference type="EnsemblBacteria" id="BAF90313">
        <property type="protein sequence ID" value="BAF90313"/>
        <property type="gene ID" value="AZC_4315"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4315"/>
    <dbReference type="eggNOG" id="COG0304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_69_2_5"/>
    <dbReference type="OMA" id="QIGHCLG"/>
    <dbReference type="OrthoDB" id="606297at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="4"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAF90313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="420" mass="44009" checksum="4E67A56A37AE4812" modified="2007-12-04" version="1">MRRVVVTGLGMVTPLGCGVEPTWRRLLAGESGAKRVDTFDVSDLPCKIAAVIPRGDGSDGSYNPDQWMEPKEQRKVDEFIVYAMAAAKQALDDADWHPTAYEDQIASGVLIGSGIGGIEGIADTALTLKEKGPRRVSPFFIPGRLINLAGGYVSIEHGLKGPNHAVVTACSTGSHAIGDAARLIAFGDADVMVAGGTESPVNRLALAGFAACKALVTAFNDEPTRASRPYDRDRDGFLMGEGAGIVVLEELEHAKARGAKIYAEVIGYGLSGDAFHITAPTPDGDGAFRCMTAALKRAGISPGEVDYINAHGTSTMADEIELKAVERLLGNAAANVSMSSTKSSIGHLLGAAGAVEAIFSILAIRDQIAPPTLNLENPSVETPIDLVPLKPRARKIDVALSNSFGFGGTNASLVLRRYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVI3</accession>
    <name>A8HVI3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ordered locus">AZC_4318</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172838.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4318"/>
    <dbReference type="EnsemblBacteria" id="BAF90316">
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        <property type="gene ID" value="AZC_4318"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4318"/>
    <dbReference type="eggNOG" id="COG0194">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_001715_1_0_5"/>
    <dbReference type="OMA" id="EWAVVHG"/>
    <dbReference type="OrthoDB" id="1502854at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="26"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF90316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="228" mass="25424" checksum="C927D87B4BB8557E" modified="2007-12-04" version="1">MAAPATSHFSLPGWKPGSRSGLARRGLMLVLSSPSGAGKTTLSRRLLAEDDRITMSVSVTTRAPRPGEVDGKDYFFVSKERFEELRDTGALLEHATVFSNLYGTPRQAVEDALSAGRDVLFDIDWQGTQQLDQSAEQDLVKVFLLPPTAEDLEKRLRTRAQDTDDVVRQRMSKASDEISHFTEYDYILINQDVEDSLAKLKAILQAERLKRRRLTGLAGFVKGLRDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVL3</accession>
    <name>A8HVL3_AZOC5</name>
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        <recommendedName>
            <fullName evidence="5">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4327"/>
    <dbReference type="EnsemblBacteria" id="BAF90325">
        <property type="protein sequence ID" value="BAF90325"/>
        <property type="gene ID" value="AZC_4327"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4327"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025126_1_0_5"/>
    <dbReference type="OMA" id="YPSSHGC"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016915">
        <property type="entry name" value="UCP029342"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029342">
        <property type="entry name" value="UCP029342_ErfK/YbiS/YcfS/YnhG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723093" description="YkuD domain-containing protein" evidence="4">
        <location>
            <begin position="34"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="63"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="331" mass="34641" checksum="FA5F667A17D85CE0" modified="2007-12-04" version="1">MSGTAGMDRRQLLRRTCLLGGSVALLALSPVRAAEDPEETAIRSLKPGEYVWHPERAPEGPVAIVVNLPEQRCFVYRDGVRIGVSTVSTGKEGHLTPTGVFTILAKDVDHHSSLYHEASMPYSERLTWSGVALHAGGLPGYPSSHGCVHLPLAFSKLLYGITSVGTPVIISDGHNAPQDVLDPGLVLPADVTASIAAGADQKVPDGSRGPACVVASGADRRLVVLRDGVEVLSGALTVKDPTQPLGNVVYVLRPQQDGKPPRWSAVSYEGNGARAGAAQDALARLMVEPAVNARLVALLTPGATMLVTDLPADSGTRSGPDLVILDQRGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVZ6</accession>
    <name>A8HVZ6_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gntR</name>
        <name evidence="5" type="ordered locus">AZC_4376</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4376"/>
    <dbReference type="EnsemblBacteria" id="BAF90374">
        <property type="protein sequence ID" value="BAF90374"/>
        <property type="gene ID" value="AZC_4376"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4376"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_1_5"/>
    <dbReference type="OMA" id="VLLHTWE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="70"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="282" mass="31652" checksum="EBA8C2B0ABDFCB38" modified="2007-12-04" version="1">MRFFNDIFTQCFGLKAAFMGKSIKKTPELQNGQGAEADSDRPTRPKVRVRFKPMRLKLSAQEASRPLQTASLHGQLLARLREMVLDGELRPGSPLPERMLCETFGVSRTPLREAFKVLATEGLIELRPHRTPVVTPVDAEEIAHVFQLMEALEQLAGRLACTLARDEDIARLEAMHADLVAFHRDERRSDYFRQNQQIHAEITRLAANPVLLGTWSAMNAKIYRARAQANYDHERWDASLTEHEAFMALLRARNADGFAASLADHTRRTGTAVLANLAKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWI2</accession>
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        <submittedName>
            <fullName evidence="10">Aminopeptidase II</fullName>
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    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_4434</name>
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    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M29 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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            <dbReference type="ARBA" id="ARBA00023049"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
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    </evidence>
    <sequence length="418" mass="44947" checksum="4D72DB2FF25D3FE3" modified="2007-12-04" version="1">MTEHQRNVSATIDPVKLDRLAQVAVKVGLNLQEGQDLFLTAPIAALPLVRRIAEHAYKAGAGLVIPLFSDDEITLARYRNAPDASFDRAAGWLYEGVAKAFSQNTARLAIVGDNPMLLSGEDPAKVSRASKANSLAYKPALEKIAGFDINWNIVAFPSVAWARQMFPDVADDIAVAKLADAIFAASRVDNDDPIANWTAHNAALRTRTEWLNDKRFSALHFTGPGTDLVVGLADGHEWQGGASMAKNGIVCNANIPTEEVFTTPHAHRVEGHVSSTKPLSYQGTLIDNIQVRFEAGRIVEAKASRGEEVLNKVLDTDEGARRLGEVALVPHSSPISAGGLLFFNTLFDENAACHIALGQCYSKCFLDGANLSAEQIAAQGGNKSLIHIDWMIGSGEIDIDGIGADGSRTPVFRKGEWA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169981.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1453"/>
    <dbReference type="EnsemblBacteria" id="BAF87451">
        <property type="protein sequence ID" value="BAF87451"/>
        <property type="gene ID" value="AZC_1453"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1453"/>
    <dbReference type="eggNOG" id="COG0169">
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    <dbReference type="HOGENOM" id="CLU_044063_4_0_5"/>
    <dbReference type="OMA" id="CNAIRRE"/>
    <dbReference type="OrthoDB" id="1054867at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
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        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="12"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="ThiF" evidence="2">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="276" mass="29467" checksum="B4338531A6BFBC93" modified="2007-12-04" version="1">MISGTTKLIGHIGFPTESFKSPMIYNPYFEREGIDAVVVPMGCEVPDYPSFLKLFFRLSNALGTLITMPHKVTTLSLVDAASPTAAIAGACNAVRRREDGRLEGDLFDGEGFVRGMRRKGRVIEGTHALVVGAGGVGSAIAASLARAGVARITLFDSHPEAARQLAERLKRHYPALEVEVGANDPAGCDIVVNATPLGMRAGDPLPVEVERIAPSAFVGEVVMTHEITPFLAAVRARGCAFQVGTDMLFEQIPAYFEFFGLPPTTPEALRAAAQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX91</accession>
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        <submittedName>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170050.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1522"/>
    <dbReference type="EnsemblBacteria" id="BAF87520">
        <property type="protein sequence ID" value="BAF87520"/>
        <property type="gene ID" value="AZC_1522"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1522"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_5"/>
    <dbReference type="OMA" id="IDYVVCR"/>
    <dbReference type="OrthoDB" id="1180629at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="320" mass="34007" checksum="2571B5BEB8E6B186" modified="2007-12-04" version="1">MVEHHLILGGCGFIGRHVAILLARAGHKVILADRVPLSFGFDDDVAGSIAWSPFDLATADWDDLIAGIDVIHHYAWASIPSSANADPGADMKGNVLPTIALLDAMRARQEERKRRLVFSSSGGTVYGRLHRVPVREDHALSPLNAYGAGKAAAELYISTYSNLHGLDTRIARLSNPFGAGQNLARGQGAATTFLARAINNEQIVIWGDGEVVRDYVHIADAAAGLVALACANSVGASHTFNIGSGQGVTLNAIIAELETELGRPLDVRYEPARPYDVPVSVLDISAAHAALGWRPRLSFAEGIRLTLADLAAGHAFSSLR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYT7</accession>
    <name>HIS6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="1">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ImGP synthase subunit HisF</fullName>
            <shortName evidence="1">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisF</name>
        <name type="ordered locus">AZC_4498</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173017.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HYT7"/>
    <dbReference type="SMR" id="A8HYT7"/>
    <dbReference type="STRING" id="438753.AZC_4498"/>
    <dbReference type="EnsemblBacteria" id="BAF90496">
        <property type="protein sequence ID" value="BAF90496"/>
        <property type="gene ID" value="AZC_4498"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4498"/>
    <dbReference type="eggNOG" id="COG0107">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_4_0_5"/>
    <dbReference type="OMA" id="IFHYKET"/>
    <dbReference type="OrthoDB" id="1522718at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000072921" description="Imidazole glycerol phosphate synthase subunit HisF">
        <location>
            <begin position="1"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <sequence length="258" mass="27270" checksum="C675982C420F848A" modified="2007-12-04" version="1">MLKVRVIPCLDVKDGRVVKGVQFVDLRDAGDPVESARAYDAAGADELTFLDITASHENRGTILDVVRRTAEQCFMPLTVGGGVRTVEDVRALLQAGADKVSINTAAVHRRAFVGEAAEKFGEQCIVVAIDAKQVSGPGETPRWEIFTHGGRKPTGLDVVEYAREVVDLGAGEILLTSMDRDGTGKGFDTALTRAVADAVQVPVIASGGVGTLDHMVDGIREGGATAVLAASIFHFGTFTVRQAKERLAAAGLPVRMDT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-04-29" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZA5</accession>
    <name>MURB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="1">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murB</name>
        <name type="ordered locus">AZC_4560</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MurB family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173079.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HZA5"/>
    <dbReference type="SMR" id="A8HZA5"/>
    <dbReference type="STRING" id="438753.AZC_4560"/>
    <dbReference type="EnsemblBacteria" id="BAF90558">
        <property type="protein sequence ID" value="BAF90558"/>
        <property type="gene ID" value="AZC_4560"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4560"/>
    <dbReference type="eggNOG" id="COG0812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035304_1_0_5"/>
    <dbReference type="OMA" id="KMNAGMK"/>
    <dbReference type="OrthoDB" id="841869at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="232" mass="25484" checksum="339E6A7BB693658B" modified="2007-12-04" version="1">MLECSICGGTQFSSREILWDELIAAWGLCREEVEYINRQQGCFCVACRANLRVVALGEAVRDALGVEGPMTAWTADPRLAGLRVLDVNGATAISNALSHLPGYVRGNFPEVNMEALPYPAAAFDLVVHSDTLEHVPHPLRGLEECRRVLRPGGHLCFTIPVVVGRLTRSRDGLPPSWHGNSSQNSDDYLVQTEYGADMWTQVMRAGFTRVTLHQVSYPAAIAITAWTPPARN</sequence>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173104.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4585"/>
    <dbReference type="EnsemblBacteria" id="BAF90583">
        <property type="protein sequence ID" value="BAF90583"/>
        <property type="gene ID" value="AZC_4585"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4585"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_7_3_5"/>
    <dbReference type="OMA" id="MKEAMEW"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724055" evidence="1">
        <location>
            <begin position="23"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="25"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="428" mass="45407" checksum="DCECB365752DBEC4" modified="2007-12-04" version="1">MRIAALSLVSALALTVAAPALAQQTINIGHLADYSGGTSDVGQPYGQGVQDTIAWINKNGGVNGKTINSDFNEYGYQVPRALAAFKKWTSGSDKVVAIQGWGTADTEALVALVTKEQIPYYSGSYSATLTDPTGKGGPKSERAAPYNFFYGPSYSDAARAMVQWAADDWKAKGGQGKPKWVHMGANHPYPNSPKAAAEAYAKELGFEVLEPITFALTPGDYTAQCLTLKQAGANYAYLGNTAGSNISVLKACEAAGVKVQFLGNVWGMGEEAMKAAGTAANGVVFPVRTAVTWEGSAPGLATFKDISKQSDPSGNAYRSVHYMTAVCTVLYMKEAMDWADKNGGVTGPKIAEGMYQKKDWVPKGTEGVCNPSTWTATDHRPTMTVDLYRSVVSGPTDAPLADLVKSGTIKLEKVATINLPRKSELLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZT5</accession>
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        <submittedName>
            <fullName evidence="9">Permeases</fullName>
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        <name evidence="9" type="ordered locus">AZC_4624</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4624"/>
    <dbReference type="EnsemblBacteria" id="BAF90622">
        <property type="protein sequence ID" value="BAF90622"/>
        <property type="gene ID" value="AZC_4624"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4624"/>
    <dbReference type="eggNOG" id="COG2252">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024508_0_1_5"/>
    <dbReference type="OMA" id="RKGSYFF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904823">
        <property type="term" value="P:purine nucleobase transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026033">
        <property type="entry name" value="Azg-like_bact_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="PTHR43337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005353">
        <property type="entry name" value="PbuG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="472" mass="49868" checksum="1867A2136AAAA7B8" modified="2007-12-04" version="1">MRGRVGRGVMPSEIRTNTRPQDQAEPLAGEGWELKRGTGLMLERLFKLKDNGTTVRTEIMAGFTTFLTMAYIIFINPKILADAGMPHGSVFVATCLIAALGSLAMGLYANYPIAIAPGMGLNAYFAYVVVLGMGYTWQIALGAVFISGVCFVLVTLFRIREAIVNGIPHSIRIAITVGIGLFLAIISLKSAGIVAASPATFVTLGNLHEPTVILSVIGFFAVAVLSVLRFKGALLIGILGVTALSFFFAGNKLSSFVSLPPSLSPTLFALDIPGALHAGILNVVLVFFLVELFDATGTLMGVARRAGLLKDGKMERLNKALLADSTSILAGSLLGTSSSTAYLESASGVQEGGRTGLVAVTVGVLFLACLFFAPLAGSVPAYATAPALFFVACLMLRDLTELDWEDITEVIPAAVTALLMPFTYSIATGVAFGFISYAGLKLFTGRAKEVNWIVWIIAAVFLFKYAYEGSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZV6</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="2 3">
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <sequence length="243" mass="24834" checksum="CBB70589F6C77613" modified="2007-12-04" version="1">MGDSEDWRFGVRRKTGVGMIVAGGLGGRWMRAGCVLAPLAVVLAACTTTPADPISMIPPNVQATVVAEEKLREAREQANAGDPAARSTSVQDILARARAEGAAPAQGGDGAQAPAPAGALATGGAPAAPAPAGAAAPTAGKPARTAPAPREFEIVFEGTTDQPPERELAAFQKAWKAAKVSDKTQVMITAGPGGGGSAFDQALLANRRLRTVRSLLPATVNARQHYDPEFVPDTVRIVVGAMD</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <comment type="similarity">
        <text evidence="2">Belongs to the HpcH/HpaI aldolase family.</text>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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    </evidence>
    <sequence length="443" mass="49301" checksum="4C51BE3DD5D65ED5" modified="2007-12-04" version="1">MAIWASIWEARCTPVIVRLLRAILAQMGHRRIRPFAAASLRHNTAGHDRPCTGRRPPHQSIGKEFPMTILKQPIVGTMGADIVGPRNPQVEAQNPDILIPPLTDHGGIPNLKFPFAMAHNRLEDGGWAREVTQRELGTLKELAMVNMRLPPGVVRELHWHKEAEWAYVLNGRVRFYLVDDQRQTLVEDLGPGDLWLAPAGFPHAIQGLEEGTEFVLVFNDGNFSENQTLLVTELFAHTPRDVLAKNFGVPVEAFDGIPGHEKYIFRQPVPPPLEDVRKSLGAATFTDRYVFRASQIAATPFPGGATKVVDSKSFAVTNLAALFIDLEPGGMREIHWHPDADEIQYYISGKTRMTVFDAVANARTFDFVPGDVGYVPKTLAHYIENIGDEPVRVLNVFHTGEYKDVSLNNWLALTPRHLVEGHLDVGDPLLSSLRATRQAVVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2D1</accession>
    <name>A8I2D1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1854</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1854"/>
    <dbReference type="EnsemblBacteria" id="BAF87852">
        <property type="protein sequence ID" value="BAF87852"/>
        <property type="gene ID" value="AZC_1854"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1854"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_17_5"/>
    <dbReference type="OMA" id="RDYITKP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="31"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="149" mass="16234" checksum="3F9D318959C6B6C0" modified="2007-12-04" version="1">MVSSYAILSDPLAGAKRQCGGPGGDAHMAKTVMIVEDNELNMKLFHDLLEAHGYHTVETRNGIEAMDLARQHRPDLILMDIQLPEVSGLEVTKWLKADAELKAIPVVAVTAFAMKGDEERIRAGGCEAYLSKPISVAKFLETVRRFAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2S3</accession>
    <name>A8I2S3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutamate/aspartate transport system permease protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1926</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170454.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1926"/>
    <dbReference type="EnsemblBacteria" id="BAF87924">
        <property type="protein sequence ID" value="BAF87924"/>
        <property type="gene ID" value="AZC_1926"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1926"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_3_5"/>
    <dbReference type="OMA" id="QLVPMWA"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030202">
        <property type="entry name" value="GltJ/AatQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614:SF42">
        <property type="entry name" value="PTHR30614:SF42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
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    </dbReference>
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    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
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            <end position="53"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <end position="229"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="BAF87924.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="255" mass="27615" checksum="01921EEB0F5298C3" modified="2007-12-04" version="1">MKYDWSWSVFLDLSSDGVHSYLYNLGLGVLWTLGLTGATAAGALVFGSILGVFRTTRAPVLNAIGATYVEIFRNIPLLVQMFLWYFVLPEVLPKAIGQAIKGMPAPWNAFVPALLCLTFYGSARIGEQMRSGIQSLPRGQLQAALALGLTPVMAYRHVVLPEAFRLMIPPLTSEFMAIVKYSSVAMTIGLLELTGQARAMQEASFHIFEAFSAATVGYLVINGCIVLAMRWLERRLAVPGLIGAAASSPARVAQS</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1942"/>
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    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1942"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="54"/>
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        <location>
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    </feature>
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        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
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    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="93"/>
            <end position="273"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87940.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="292" mass="31010" checksum="2F888DC9D3EFDE87" modified="2007-12-04" version="1">MTAQPVAAAAPAPRAIPSEAEIEAKARARIKARRTLVITLRIAILVAVLGFWEIGAETGFIDPFFFASPSGIADQIWIWITEGTSQGPLWTQIVVTLEETVLGFIIGAVGGVVCGILLGRNKLLADVFSIYIKIANSIPRVVLGSIFIIALGLGMPSKVALAVVMVFFVVFANAFQGVREADRAMIANAQILGASPFKITTTVIIPSAMSWILASLHVSFGFALVGAVVGEFLGAKQGVGLLIATAQGAFNANGVFAAMIILAVLALVMEFLITLVENRLVKWRPVPFHEQN</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1988"/>
    <dbReference type="EnsemblBacteria" id="BAF87986">
        <property type="protein sequence ID" value="BAF87986"/>
        <property type="gene ID" value="AZC_1988"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1988"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_0_0_5"/>
    <dbReference type="OMA" id="PWIAREG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0536">Nodulation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="69"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="315" mass="34928" checksum="ACA98F79EFE123B9" modified="2007-12-04" version="1">MMPANVTSDRDFRGYAGRPPQVRWPNGARLALSIVVNVEEGAELSIGAGDERNESVYETIDEIVGARDLCMESHFEYGPRAGWPRIRTLLARYGVAATLNANGRALALSPWIAREGVADGHEVAAHGWRWERHALMDEAREREAIARTVAAITATAGSPPRGWHTRSATSVNTRRLLLEHGGFLYDSNAYNDDMPYLVREAGEDCLILPYAFDTNDMRFQPGGGFIFADDFARYCIEAFDRLYEEGAHAPRMMSVGLHLRIIGRPGRIGGLERFLAHVASKPGVWFARRDAIARHWLSAIGRDDIVRRALGADAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3B2</accession>
    <name>A8I3B2_AZOC5</name>
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        <recommendedName>
            <fullName evidence="4 6">Signal peptidase I</fullName>
            <ecNumber evidence="3 6">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2003</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase S26 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170530.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2003"/>
    <dbReference type="MEROPS" id="S26.001"/>
    <dbReference type="EnsemblBacteria" id="BAF88001">
        <property type="protein sequence ID" value="BAF88001"/>
        <property type="gene ID" value="AZC_2003"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2003"/>
    <dbReference type="eggNOG" id="COG0681">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028723_1_2_5"/>
    <dbReference type="OMA" id="SDSRFWG"/>
    <dbReference type="OrthoDB" id="1741894at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="7">
        <location>
            <begin position="14"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="250" mass="28442" checksum="A177777007473700" modified="2007-12-04" version="1">MTATSDSKKDGGFLETVRVIVHALLIALVIRTLLFQPFNIPSGSMKDTLLIGDYLFVSKYSYGYSRFSLPLSPPLFTGRIWGKEPTRGDVVVFKLPKDGETDYIKRLVGMPGDDIQMIDGVLHINGVPVKRERLSDVMEDDGTGRQAPVKRWRETLPNGVSYETLDIVDNGFYDNTPVYHVPAGHFFMMGDNRDNSADSRVLSQVGYVPFENLVGKAQMIFFSIDEHTPAWQVWNWPWTVRWTRIFSMVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3S0</accession>
    <name>A8I3S0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1647</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170175.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1647"/>
    <dbReference type="EnsemblBacteria" id="BAF87645">
        <property type="protein sequence ID" value="BAF87645"/>
        <property type="gene ID" value="AZC_1647"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1647"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131462_3_2_5"/>
    <dbReference type="OMA" id="CYVAEFL"/>
    <dbReference type="OrthoDB" id="1944417at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042221">
        <property type="term" value="P:response to chemical"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="119" mass="12583" checksum="4C111ACBF12AB199" modified="2007-12-04" version="1">MSELVILLVLSVVCDVCGQLAFKRGADALPPASDLARFLPALFTQPWLLAGIAVYGVEFIVWIRVLMLAPLGIAFPLASLNILGIMVASHLILKEPATRRQYAGAVLVTAGIALVASSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4P6</accession>
    <name>A8I4P6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_1756</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87754">
        <property type="protein sequence ID" value="BAF87754"/>
        <property type="gene ID" value="AZC_1756"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1756"/>
    <dbReference type="eggNOG" id="COG2239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037408_2_2_5"/>
    <dbReference type="OMA" id="IYYAYVT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <dbReference type="EMBL" id="BAF87769.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="294" mass="32305" checksum="779793E8BFF13C80" modified="2007-12-04" version="1">MPLAPMGSTLRMLRPAPHVLAFYDGRVPDTRLWSEEPNWLDDGAYALGIASYAILEGAEALVYDTHISLPHARFIRRTLEEMGVRHMRVVLSHWHDDHVAGNEVFADCEILANALTADILRDKQAKLESGDPPIRPLILPNRTFSGEITLQVGALPVTLRQMDIHSCDGTVVLLPDGLLLAGDTLEDPITYVDEPERLAIHLEGLAEMARWPLSRILPNHGSAEVIAAGGYQPDLIAATRRYVERLIAARTDPGLAARDLRAFVPEDFASGAIGYFAPYEAVHRQNLAAVTEAS</sequence>
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                <person name="Liu CT."/>
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                <person name="Wakao S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
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                <person name="Lee KB."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="3" key="2">
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            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="STRING" id="438753.AZC_1806"/>
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        <property type="gene ID" value="AZC_1806"/>
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        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF87804.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="230" mass="24778" checksum="054896FC207BFCE2" modified="2007-12-04" version="1">MDANLAGRLNFTHRPPTKEALPPGRHDLGLFEQRDAVLVVPEGVDASRPTPLVVLFHGGGGSAQKILPMLEAHAQANGFLLLVPQSLYPTWDIVIAGNGPDRERLDIALAEVADRFTLDPEHLAFAGHSDGGSYTLSLGLTNGQFVTHLIVSSAGFMSVHHQEGAPRIFISHGINDEQIPIDRSGRAHADLLKRAGYDVTYIEYNGPHAYQPPVVALAVNFFLADLLATA</sequence>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <comment type="similarity">
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    <dbReference type="KEGG" id="azc:AZC_2712"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="GMTITIR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="364"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="458"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="610"/>
            <end position="672"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="714" mass="75950" checksum="B3570D9E79B4C2FE" modified="2007-12-04" version="1">MAQACHAQNVAEFPGAFGMTITIRTALVSLFCVMSAVIIVMCGLTLSTAKRNYDGAKEAASLASVEMDILQALSVFRLERGSMVTLLTVEGAYTPAQQEQMNQRRQIAAKAMTAAAPKIDALTHQKLLAIGKDLKSQFANMDRLREAADRDLPRPLAQREAGLSKRINDDGGRLMTTMEKFLDTAEDGIRANDPTLSQFILSRTMAWDVRSYVGTINGMLNTVVGAERPFKPEEDRTVTDLDGRVTAAWKPVLDVADNDDTSPDLKKSIQIAQETYFGGSFKKLRDDILSNLRNGKPAGVALNAWRDASQTQNTFSDVAMVSIKSIVEAANAREATAFRNLLTYSAILVFAVALTVVGLLVVLRRVTGPISRLTHVMTDVASGDLEVEIPGTQRHDEIGAMAKALMVFKESLVRNRGMEAEAARQRTEAELERKRMMQNLAGEFEREVGGIVGTVASSSQQLQQTAGRMAKAAEKTSSQSTAVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVLQSAEMSKVAVAEAEKTGTVIQDLAQAAGRIGAVVGLISSIAEQTNLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTQQAVTVIEGVGLQIRKMSDVAASISAAVEEQGVATREIVRNVDQAATGTNTVTSHIADVAKTADETGEAAGQVLQASTALTDQAKRLEAQMQQFLATVRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9K3</accession>
    <name>A8I9K3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Pyrroloquinoline-quinone aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2801</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171325.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2801"/>
    <dbReference type="EnsemblBacteria" id="BAF88799">
        <property type="protein sequence ID" value="BAF88799"/>
        <property type="gene ID" value="AZC_2801"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2801"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007015_1_2_5"/>
    <dbReference type="OMA" id="WSAWVAD"/>
    <dbReference type="OrthoDB" id="1297285at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="796"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="941"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="1073"/>
            <end position="1160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1184" mass="125794" checksum="36F4ECB6D0055340" modified="2007-12-04" version="1">MTEPAPSPDALLARAGTLAILRPAQHVKGLVPTAPPPEGALDLFLFLDDEGRTLAFNGHVDLGTGIRTALAQIVAEELDLPIDRVTMVLGHTGGTPNQGATIASDSIQISAQPLRRAAAQARHHLVALAAEALGLPEADLTVTDGVVHPKAGGNAGVSYAALIAGRRDRLMLAESVALKPVSDYRIVGQRMPRVDIPAKATGTFTYVHDVRVPGMLHGRVVRPPYAGIDAGDFIGKSLIAVDESSVADIPGMVAVVTMGDFVGVVAEREEQAAEAARRLKVRWKEPPPLPADLTDIPNALRTNPSKPRLLHERGDVEAAHSAAAQQMDRTYVWPYQMHASIGPSCAVTDVRPEGTTVWSGTQNPYPLRADIALLLGLPEETIEIVRFEAAGCYGRNCADDVAADAALLSRAVGRPVRVQLTREQEHAWEPKGAAQLMEIRGGITADGSPAAYDFSTRYPSNAAVTLALLLTGRVPADNPVFEMGDRTAIPPYAYDNMRVVAHDMAPIVRAAWLRGVSALPNSFAHESYIDELAAAAGVDPVEYRLRYLHDPRAVDLVKEVAAKAGWEHRTGARQQVVEGDIVRGQGFAYALYVHSKFPGYGAAWSAWVADVEVNKATGDVNVTRVVVGQDSGLMINPAGIEHQIHGNVIQSTSRALKEEVSFSKTEVASREWGAYPILTFPEVPVIKVVLMPRPEEPPLGSGESASVPSAAAIANAIFDATGVRFREPPFTPDRVRAALTGEAPPPDPKPEKKKRSWFALAGAALAGALGMASVALPIRGAIAPITPPDPTSFSAEMIARGKQLAALGDCAVCHTLPGGVTNAGGRAMETPFGTVYATNLTPDPETGIGRWSYAAFERAMREGISRDGRHLYPAFPYTAFTKTSDTDLQALYAYLMSQPAVSAPTPEAKMAFPFNIRPLMAGWNALFLKPGQMEADPARSPQWNRGAYLVDGLGHCGACHTPRNVLGAEKTGAAYLAGGMVDGWEAPALTALSSAPIPWTEEALYSYLRTGFSPHHGTAAGPMAPVVQELSHLPDADIRAMATYLASFSGPAPADPAARAAELQAKASASLRPLDTLGGKLYEGACAACHSESGPTLFGVRPELALNTNVHAARPDNLIRVILDGIPSPAARDLGDMPAFRESLDDGQVAALVRYIRAKFAPDAKPWEGVDAEVTRLRSAPTTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9Z7</accession>
    <name>A8I9Z7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gntR</name>
        <name evidence="5" type="ordered locus">AZC_2444</name>
    </gene>
    <organism evidence="5 6">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Lee KB."/>
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    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="561"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="71"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="392"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="590" mass="63225" checksum="2DD624BC270BA3B9" modified="2007-12-04" version="1">MSTALSAPARAAARRKAFGRALMAAPLIVLLLVFLVYPVGQLLLLSVWGAKGFSLQAYAPLFSSPLYINVLLITLKISAITTLLSVIGGYPIAYLISVSAPERKARLLFWVLLSFWTSFLVRAFAWIVILGRRGVVNHLLLSLGLADQPADLLYNFSSVIIGMVHALMPLAILTMLSVMENIDRTLPRAASTLGARPGTAFWKIYFPLSLPGVAAAAIMVFVTAIGFFIVPALLGGRRETMITQLIIDQVLQTMNWGFAGAISVLLLVVVLVVFLAYDKLVGLSTMTGSGSTRPAKATSGGLSQRIGDALLTALGTASDALISLFPHRKTASGKAPLPLVFFVVALLVLMSLPAVLMIPLSFGSGGLNWPPRGFTLEWYEQMLQSPVWGQALMRSLLVGLGTGFLAMLIGTPAAFLLVRSDMKGKGAILAFVLSPIVVPRMIIAVGLFYMFARIGLVGTALGLILGHTVVAVPYVVMTMMAVLRNYDTRLDLAAQSLGARPLATLRYVTLPILGAGMLSSFLFAFATSFDELTIALFASGGLNATLPKQFWDEVTLQVSPMIAAVSTCLFIFIAVLIFVADRLRRRSLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAR4</accession>
    <name>A8IAR4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 11">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplV</name>
        <name evidence="12" type="ordered locus">AZC_2549</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="7">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="8 11">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8 10">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171075.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2549"/>
    <dbReference type="EnsemblBacteria" id="BAF88547">
        <property type="protein sequence ID" value="BAF88547"/>
        <property type="gene ID" value="AZC_2549"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2549"/>
    <dbReference type="eggNOG" id="COG0091">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083987_3_0_5"/>
    <dbReference type="OMA" id="KRIQPRA"/>
    <dbReference type="OrthoDB" id="1666043at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018260">
        <property type="entry name" value="Ribosomal_L22/L17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00464">
        <property type="entry name" value="RIBOSOMAL_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8 10" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="126" mass="13891" checksum="A1401BEAC9DA98BA" modified="2007-12-04" version="1">MGKQATPRALADNEAKAVARNLRVSPQKLNLVAGLIRGKKVSTALADLEFSRKRIARDVKKCLESAIANAENNHDLDVDDLIVAEAHVGKGLVMKRFSPRARGRASRIEKPFSHITIVVREVEERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAU7</accession>
    <name>A8IAU7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
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                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_3098"/>
    <dbReference type="EnsemblBacteria" id="BAF89096">
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="GAF-like_dom_sf"/>
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        <property type="entry name" value="HisK_dim/P_sf"/>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
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    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="1538"/>
            <end position="1752"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89096.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="1754" mass="188347" checksum="11042A080AEDFF8B" modified="2007-12-04" version="1">MSSDWALIPEGLSRKDGRLALVLGDPGAVPFRQAANACPVLLPRLALAAELAAAVRAMHAAGVVHGDIRPAHILARADGGRVWLTGFAHATARGQVPEGGLTDPSADALPYMSPEHTGRTGRIVDERSDLYSLGVVLYELLAGVLPFHAQRRMEWIHAHVARVPAPPRERADLPEAVSAIVVKLLAKEPASRYQSAATLEQDLRRCVATLRQKGTIPDFVPGESEVLLGNPTPQRFLGRTSELAHLTTAAARVAADGRAEGVLVQAEAGAGKSALAAAFQRRVEPHMAWFATAKCEPRDQPYAALGAALRSLVIRALAAAPEALEALAAGWAHAFGDDVAFLLDLVPELAPLVAVPSRPASLPLMETRARVHRLLAGVLAGFARQRHFLVLVIDDVQWADVATLDFIGELLGAETPAPILFLGLARPSQEMALLRLASHRRIETMDLVPLSVAETRDLVAGLLRAPTSAVGGLAELVWTKTGGNPFFVCQFLSVLAHRGGLSFDPASGRWVWDAAVIAAAGIADNVATLIAGKILRLEPDLQKLLMFLASLGSQFDAELLATVEPVHGGALEPALGKAVEAGYVIATPTGHRFAHDKIRDAAYQLIDPSSRATWHLGLARVLAGAVREGAAARLFDAVDQYGLCLRLLEDANERLAVAELYLDAARRARRSGSYEAALGLVRTATALLPQDRWNTCYRTSFELAVLGAECAAMHGEHAYAEAQLAAAGVHAEELVDAALATRLQVSLLTALDRSDEAVRTGLGFLSRLGPAWSFAPGDTVEEEYRSLVSRLGTQPVGVLIDAPALTDPLRLAAMEVLVEVTSPASFIDRRLHDLVPLRMVNLVLEHGLCDAAAFAFEHAAMVIGPAFGDYALAHALGQLGLDLVNRRGFERFRAKVEMCFGSLVSPWTRPLAERRDLIRKSFDSALAAGDANFAAYSCNNLVTNMLSAGEPLVAVEAEIERGLAYAAGVRLVRVELILKAQARMVQQIRRGIAADPQEEAATEALLEADPRLAVAAFCYWTRKLQCCVLSGRFAEAAQAREKAEHYAWTCPYFLETAVLALFGGLALSLPRAAGEEGPWRDAFRRHAAQMAHWAAHSPSNFEGGARLLAAEAARLDGRDVEAMTLYERAVQGARTLGLSHHEALASECAARFHASRGHGLIASAFRRYAASAYEVWGAHAKAAELGSGSGGIVQSDPAVPRLEADLDISLMLDGSRALSAEIVLPQLIERLLTLAMQHAGADRGLLTLVRDGRPYAAASAVSEAGGLHVWMSEVGLYQCPFPVSLVNVVLRTRTTLMLADVRETPEFGDDPFFAHAPRAVLALPLKKGGEVVGVLYLENAHLPDAFSASRQALLEVLGSQAAISLENARLYAELQTDIARRKTIEQELRRSRAVLAAAQSMMQIGSWYWEAANRTILWSDELFRILGLDPLEHKPSFQLFWSRVHPEDKARLKAAIHAVRASVQSASVEFRIVLPGVEVRHIECIIPAMLSAAESRGDFVGTVMDVTEKHRADERLRAAQAELERVAGLTTMGELVASVAHEISQPLAAIVANASAGIQWLKRSPPRADQAEQVLARIAAQGTKAGDVIRGLRSISAKSDAHMAPFDVPDAVDEAIALLADRLRKAQVLVRRTLSPSERIAHGDRALFQQVVINLAGNAIEAMRGSSGARTLSITTRSQADAFMEIEVADTGEGIPPEQVARIFDPFFSTKPDGMGMGLAICRSVVEAHGGTLGVDTGPTGTRFFFSFPRGDHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBV5</accession>
    <name>A8IBV5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="BAF89122">
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    <dbReference type="OrthoDB" id="1885367at2"/>
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            <end position="26"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="134" mass="14299" checksum="EAAFB7AEA425AF3D" modified="2007-12-04" version="1">MILTPSRIAQIVFAATLAATGSAAQAASHSDEQILKLAPNARMEQRCNARAMGVIGREHKGLRPDELVAYAYADTVINGGTIRAPGAAVRSGGKWYHLSYACQTADSGTEVKAFDYALGTVIPRAEWAEHFLVP</sequence>
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<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC17</accession>
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    <organism>
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        <lineage>
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    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="similarity">
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    <dbReference type="STRING" id="438753.AZC_3148"/>
    <dbReference type="EnsemblBacteria" id="BAF89146">
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    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00678"/>
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    </evidence>
    <sequence length="162" mass="18226" checksum="65A0AE3593E80514" modified="2007-12-04" version="1">MSQTPPPNRLCAVTLDDASIGRSGADVEHERAIAIYDLLEDNRFTPVGDPGEGPYTLHIGLMDNRLVLDIRREKGSEPVVQHHLSLSPLRKVVKDYFLICESYYAAIRTASPTQIEAIDMGRRGLHNEGSTLLQERLKDKVEVDFDTARRLFTLICALHWKG</sequence>
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        <lineage>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; alginate biosynthesis.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AlgF family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF89216">
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    <dbReference type="GO" id="GO:0042597">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00005182"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00010033"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="232" mass="23547" checksum="769F5F62201F1CB0" modified="2007-12-04" version="1">MMGQRHLEAGFAVLLAAAVMFPGLAGAQTAPLTRLYAPKPPQGSAYVRVVNPTAAAAAVSLAGGAPVTLGPATERALAYRVAPGGKPVTLTVDGKPVAGEIVPVADGFLTIALSGGPGGWSAKPLPDATEGRDDLKVMLRFYNLAEGCTAALAVADGPTVFDGVPQSESRQRAINPVDASLVGRCGPLASAPVRLPKLKAGDHYSLFLGGNATAPILQGQVDETEPYRGTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
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        <name evidence="3" type="ordered locus">AZC_3226</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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    <reference evidence="4 5" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="472" mass="47594" checksum="1E8AB55CF9309A7D" modified="2007-12-04" version="1">MSGTGEDGVRFAAPLDLADPRLERLIVRLAVPSVAGLSITALHHVANAAFVGLLSGQALAAVSIAVPIFALVAAIGHGLGIGGAASIGRLLGAGDALDAGRAASATLALCVLLGGAAGIGLFWGAGGVLALFSPGPDLAPIAATYLRLLAVSCPLLLAQIACDFIAIAEGNSRFSMWTLLGAFALNIVLDPLLIFGFGLGVEGAALATILSQLAALAAYGLYFGRRWGRVRLGVGGLGLKARLLRPILAVGVPAGLSSALSALAFAVVYAMAGIHGGDEAVAGVSIAFRLLTLGLLPVIGFCLGAQPVLSFAAGAGDRIRLRAATLFMARVALGFTLFYAVSMMLGSAPLVGLFTADARVADVARRGLILFHAGFALTGLHQVLVILLQAMERARLAAVISLAPQGYLLLPLLYGGAALWGMDGVLAAPPLAMGLTALVSAALLLREVRRLPTARSRKSSPSLAAEGAGGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICS0</accession>
    <name>A8ICS0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative siderophore biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Siderophore biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3245"/>
    <dbReference type="EnsemblBacteria" id="BAF89243">
        <property type="protein sequence ID" value="BAF89243"/>
        <property type="gene ID" value="AZC_3245"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3245"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039848_0_0_5"/>
    <dbReference type="OMA" id="FELYWAR"/>
    <dbReference type="UniPathway" id="UPA00186">
        <property type="reaction ID" value="UER00284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019290">
        <property type="term" value="P:siderophore biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019432">
        <property type="entry name" value="Acyltransferase_MbtK/IucB-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM01006">
        <property type="entry name" value="AlcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlcB" evidence="3">
        <location>
            <begin position="253"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="443" mass="48716" checksum="A45A82817C20C725" modified="2007-12-04" version="1">MASLPVPHDRARLVLAWLVVPHRALPAAALLARTNEAPPHLGAGSKKTPARSAGAKSSRGSYVLSKRSHQARPSGTGDCMTIAELVTLTGQRRPFVALAATDRPVEVHVGAQSVRIAAGDASVSLGWQRQGGGALLTGALLDPRADMLLLAACEALFGSFPELTHVALAPDLAPAAVAGLITHGPAQLVDGLPRIEPDLLWQMSALWLPGSGGVFPQRLVTENGIRHPRRPPMRDGLLYARSIPWLGQSITFETADPERHLPAFHRWMNDPRVAEIWEETGDLAQHRAYLEERRADPHVVPVIGSFGGVPFGYFELYWARENRLGPHYEAQDYDRGWHVLVGEEAFRGKAYISAWLPSLMHFMFLDDPRTQRIVGEPRATHAQQIRNLDRSGFAKVKHVDFSHKRALLVMLLRERFFGDRLWQPDFDATAQPVLPVAAQAVPA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICW0</accession>
    <name>PYRB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="1">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Aspartate transcarbamylase</fullName>
            <shortName evidence="1">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pyrB</name>
        <name type="ordered locus">AZC_2851</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171375.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ICW0"/>
    <dbReference type="SMR" id="A8ICW0"/>
    <dbReference type="STRING" id="438753.AZC_2851"/>
    <dbReference type="EnsemblBacteria" id="BAF88849">
        <property type="protein sequence ID" value="BAF88849"/>
        <property type="gene ID" value="AZC_2851"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2851"/>
    <dbReference type="eggNOG" id="COG0540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043846_2_0_5"/>
    <dbReference type="OMA" id="FPTEREY"/>
    <dbReference type="OrthoDB" id="1844275at2"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000321072" description="Aspartate carbamoyltransferase">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <sequence length="321" mass="34923" checksum="2E66C91ACBAAACCB" modified="2007-12-04" version="1">MITAPFFTLDRRDLLGIEGLSAPEIVGLLDLAEEFVVLNRQIEKKRSTLRGRTQVNLFFEASTRTQSSFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMRPDILVVRHHASGAVALLARKVDCCVVNAGDGAHEHPTQALLDALTIRRNKGRIEGLTVAVCGDVLHSRVARSNILLLHTLGARVRVVAPSTLLPTGIENFGVEVHRSMESGLEGADIVMMLRLQRERMAGSFIPSVKEYFHYYGLDEAKLKRAKPDALVMHPGPMNRGVEIDSAVADGAQSLIREQVEMGVAVRMAVLDALARKLPNATGAERD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICW3</accession>
    <name>A8ICW3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2852</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="596" mass="64695" checksum="3E192D29A031274B" modified="2007-12-04" version="1">MQTYQPPLRDMRFVLHELHGSDALKDLKGCEDISTDLIDAVLEEAGKLVTEVLAPLNVVGDAEGCRYENGVVRTPTGFTDAYKTYVEGGWNGIACDPEWGGQGLPASVTKFVEEMMCSANLSFGLYPGLTHGAYQALNSHASQELKERFLPKMVEGVWSGTMCLTEPHCGTDLGLLRTKAEPQADGSYKITGSKIFISAGEHDLTENIIHLVLARLPDAPKGIKGISLFLVPKFLPTEDGRPGPRNGVTCTGIEHKMGLNGSATCQMSFDEATGWLVGTPHKGMAAMFTMMNSERLSVGTQGLGIGEASYQSAVAYARDRVQGRALSGAKYPEKAADPIIVHPDVRRSLMTMRAYNEGCRALSGWVARNLDLMERSNDPEERQQAEDFTALMTPIVKALFTDLGFTNASLGVQVYGGHGYIRDHGMEQYVRDARIAMIYEGTNGIQALDLVGRKLPAHTGRYLRSFFHPVLAYIDAKMDDENLGPLVGPLGKAFGALQLATGHIAEKGLKDAEEAGAAATDYLRLFGLVALGYMWVRMAEVAFEKRATANGEAAFYDAKITTARFFIDRLLPEVAGLWGAIKSGKSSMMALPDDAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEG7</accession>
    <name>A8IEG7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxypyruvate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3489</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hyi family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172012.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3489"/>
    <dbReference type="EnsemblBacteria" id="BAF89487">
        <property type="protein sequence ID" value="BAF89487"/>
        <property type="gene ID" value="AZC_3489"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3489"/>
    <dbReference type="eggNOG" id="COG3622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050006_1_2_5"/>
    <dbReference type="OMA" id="YVQYDIY"/>
    <dbReference type="OrthoDB" id="1007505at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017643">
        <property type="entry name" value="Hydroxypyruvate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026040">
        <property type="entry name" value="HyI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006241">
        <property type="entry name" value="HyI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03234">
        <property type="entry name" value="OH-pyruv-isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="3">
        <location>
            <begin position="21"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006241-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="259" mass="28576" checksum="77A499BBF53CAF17" modified="2007-12-04" version="1">MPKFAANLTMLWNEIDFLDRFAKAAEAGFKGVEYLFPYAYPKEELAERLEKHGLTQALHNLPAGEWAKGERGIAVLPDRVGEFQDSVGTALEYAKVLKTQTLNVLAGIAPKDVPAEKIYETLVSNLKFAAAEAKKAGIPLVVEAINTRDIPGFYLNTTKQTLSLLDDVGPQDVFFQYDIYHMQIMEGDLVPTLRANMARIKHIQLADNPGRGEPGTGEINYPFIFKAIDDAGYTGWIGAEYKPATTTDAGIGWFAPYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEN6</accession>
    <name>A8IEN6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TRAP dicarboxylate transporter-DctP subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3515"/>
    <dbReference type="EnsemblBacteria" id="BAF89513">
        <property type="protein sequence ID" value="BAF89513"/>
        <property type="gene ID" value="AZC_3515"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3515"/>
    <dbReference type="eggNOG" id="COG1638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_2_3_5"/>
    <dbReference type="OMA" id="WPASGIW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="364" mass="38500" checksum="4100E3FE6831C4F0" modified="2007-12-04" version="1">MPSSCSGGERRGAVPADCLLIRSSLMTLSILRAAGLAFLVAGGLNAAAFAQSAPPAKSEPVVWELIDEYPASAIPGQADATFAAAVEKATGGKLVIQPIPDAKSGLRSREQLKAVSEGRFAMADSFGGALAEDSPLFLLSSLPFLTASADEARQLYVAARPLYEAEFARRGQKLLFVTPWPPSGIWSAEAVSSPAALKALKIRTYDQTGAELFAATSTRAAVVSFSDLMPKLKTGEFNAVLSSGDGGAGRELWVHVRHFSQITYAVPLSFGTVSLTAWNALDPQTQAAVLRAGEETTQAQWKAMEGRVAANYQRMRENGVVIDEAPPAAVMDLLRTAASKSIVRWRTTVTPEAAAVLDTFAATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEP6</accession>
    <name>A8IEP6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="9">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">potA</name>
        <name evidence="11" type="ordered locus">AZC_3519</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172042.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3519"/>
    <dbReference type="EnsemblBacteria" id="BAF89517">
        <property type="protein sequence ID" value="BAF89517"/>
        <property type="gene ID" value="AZC_3519"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3519"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_5"/>
    <dbReference type="OMA" id="EITVFWQ"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015417">
        <property type="term" value="F:ABC-type polyamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="30"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF89517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="388" mass="43183" checksum="A8C58B71B7820E87" modified="2007-12-04" version="1">MAADKARTQIIGAVRRSFAPWDDPAAKPLIRFETVVKRFGAFTAVDRVSLDIYEREFFALLGPSGCGKTTLMRMLAGFEPPTEGRILLAGEDISAMPPYRRPVNMMFQSYALFPHMNVWDNIAFGLRQDKMSKADIAARVEEMLALVKLEPFAKRKPHQLSGGQRQRVALARSVAKRPKVLLLDEPLTALDKKLREETQFELMDLQMTLGMTFLIVTHDQEEAMTVADRIGVMNQGQLVQVAPPAVIYEQPATRYIADFIGDVNVVETKVAAVAPDGVTLGCEKTAYPIRIAQSVDVKPGDSAWLVIRPEKLRIALEPPVPAESNIFEGKVWDIGYLGDLSIYHVELACGTRIKVSKPNVSRLVERPITWDDKVWVSFAPDAGVVLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEQ3</accession>
    <name>A8IEQ3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3521</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168584.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0053"/>
    <dbReference type="EnsemblBacteria" id="BAF86051">
        <property type="protein sequence ID" value="BAF86051"/>
        <property type="gene ID" value="AZC_0053"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0053"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_1_7_5"/>
    <dbReference type="OMA" id="KLAMEHM"/>
    <dbReference type="OrthoDB" id="955232at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="8"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="325" mass="35373" checksum="8017D09CAFF9508E" modified="2007-12-04" version="1">MPGNPVLLLVGGTGFVGGHLAPALVAAFPRHRRVMLSRGEASARPDWETLEGDLSDAVAMDRIVAELRPEVVIHLAAQASVVSDPNATWVVNCGGTFNLARAVARHVPRGLFFFSSSGEIYGESFNDGPAREDTAPRPMNAYAGSKLAAEAVLRALLPQEWRLVIARAFNHTGPGQDERFVLPSFAAQIARIEAGQIAPRIRVGNLAAERDFLHVKDVVAAYIALLHYEGPERRILVNVASGHVYGISDLLERLRGSARRPFEVEIDPARMRPSDIPCAAGDPSLLKQLVNWTPRHSIQETLDELLDWWRAAVLSGRGEGVSTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG81</accession>
    <name>A8IG81_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gmd</name>
        <name evidence="6" type="ordered locus">AZC_0054</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168585.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0054"/>
    <dbReference type="EnsemblBacteria" id="BAF86052">
        <property type="protein sequence ID" value="BAF86052"/>
        <property type="gene ID" value="AZC_0054"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0054"/>
    <dbReference type="eggNOG" id="COG1089">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_14_1_5"/>
    <dbReference type="OMA" id="FVKSSWQ"/>
    <dbReference type="OrthoDB" id="955232at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="6"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="325" mass="36226" checksum="A84660A075D52119" modified="2007-12-04" version="1">MTKRALITGITGQDGAYLSQFLLEKGYEVHGVVRRSSHLGVADHRLRWLGVEKDVAMLDGNLSDLSSLIRLVEQVKPDEVYNLAAQSFVASSWQQPILTANITAVGVTNVLEAVRIVAPQARFYQASSSEMYGKIQEAAQSETTPFYPRSPYAVAKLYGHWITVNYRESFGLHASSGILFNHESPLRGIEFVTRKVTDGVARIKLGLEKELRLGNIDAKRDWGHAKDYVRAMWLMLQQDAADDYVVATGTTTTVRDMCRIAFSHVGLNIDDHLVIDPAFFRPAEVDVLLGNPAKAKAKLGWEPQITLDQMIREMVDADLARLKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGK3</accession>
    <name>A8IGK3_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0176"/>
    <dbReference type="EnsemblBacteria" id="BAF86174">
        <property type="protein sequence ID" value="BAF86174"/>
        <property type="gene ID" value="AZC_0176"/>
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    <dbReference type="KEGG" id="azc:AZC_0176"/>
    <dbReference type="eggNOG" id="COG1454">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_007207_0_0_5"/>
    <dbReference type="OMA" id="PGELMDY"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000000270">
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
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    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="13"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="376" mass="39092" checksum="45CD3BE43952DF52" modified="2007-12-04" version="1">MTLAFSPIDLVRPPRIAFGSGTLSAVREWLAARGLKRALVVADGFNAGRIELLGLEGAVEVFGEVKPEPDLPNLEALLAKAESFGPDVVIGFGGGSAMDLAKLAAVLPGSGQSLHDVVGPEKVAGKRAALIQVPTTAGTGSEAGTRALVTDPVTQNKLAVQSLHMLADLAVVDPDLTLTVPPAVTAATGVDAMAHCVEAFTSRKAHPTIDLYALEGARLVGRFLPRAIKDGSDREARAGLALASLYGGFCLGPVNTTAGHAVAYPLGTRHHIAHGAANALIFPHVLAFNAPAVPEKTAQVLAALGFPASSDPAVVLKATREWCAALGCEMRLSAYKVPADDLPIMATEAHAIRRLLDNNPRDMSREDILAIYQAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHD0</accession>
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        <recommendedName>
            <fullName evidence="1">ResIII domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3259</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171783.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3259"/>
    <dbReference type="REBASE" id="16448">
        <property type="entry name" value="Aca571ORF3258P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF89257">
        <property type="protein sequence ID" value="BAF89257"/>
        <property type="gene ID" value="AZC_3259"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3259"/>
    <dbReference type="eggNOG" id="COG1061">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_015668_0_0_5"/>
    <dbReference type="OMA" id="EGHKAYS"/>
    <dbReference type="OrthoDB" id="13585at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="85"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04851"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="863" mass="96018" checksum="CCAD5ED3D5F54666" modified="2007-12-04" version="1">MFRQLDYQDRVLSTLDAYLDLLKEKKARADKVAALAEQDPDLGLAIPDFAKDAWEAMKAANKLPASRAAIPFSPRMDGCERPVPNAVLKVPTGGGKTWLAVSAVSRVMGRYLDRNTGFVLWIVPNEAIYTQTLKHLKDRQHPYRQALDRAAAGRVKIMEKTDRLDARDVESNLCIMLLMLQSANRETQDSLKMFQDRGDVHGFFPPEGEQQAHQAVIDRTPNLSAYTGMFPMVKDSLGNALRIIRPVVVMDEGHRAISDLAFGTLYGFNPCFVLELTATPQDVQPRGGRNPREGRYANVLVEVTGRELDREGMIKMPLNLDPRQGNDWKATLNAALAKLNALDAEARQLRADTGRYIRPIMLIQVERTGADQRESGHIHAEDVKDWLLTAGFDQAEIAIKTAQQNDLNDPENQDLLSPTNRVRAIITKQALQEGWDCPFAYVLCSLAASANLKAMTQLVGRILRQPGALKTDVEALDECHVITHHADTATVVGAIKDGLEQDGLGDLVLRVTQDDKSGTGKTARTINRRPAFASTEIYLPKVMVVESGDARELDYETDVLSALDWRGFDPQDIADRVPENAQAAESQLQRIRLAEDGDELFVGETVAANAEILAFDPAHAVRMISDIVPNPFVGREIVGATVAALRARGFDDAKLGLLASLIVEELRKGLEAARNARAEALFKAEVAAGRIQFRLRLDGRNWRMPFSIETTEPENARQLLNRAGGPLEKSLFAPVYENELNSDERDVAVYLDGEKTLAWWHRNVARTQYGIQGWKKAKIYPDFIFAVQRDGEAKRITVLETKGDQLDNLDTAYKREALAFLSDHFEWDEATPVGELELVNNGETVEGTLILMSEWKAKLPAYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHF3</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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        <name evidence="2" type="ordered locus">AZC_3267</name>
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    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <location>
            <begin position="120"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89439.1"/>
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    </evidence>
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        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="protein sequence ID" value="BAF86210"/>
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    <dbReference type="HOGENOM" id="CLU_420163_0_0_5"/>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FRG" evidence="1">
        <location>
            <begin position="28"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="652" mass="74426" checksum="3FE37BBA8F3B6419" modified="2007-12-04" version="1">MEDGFFSKNIRAHDSENALEICQYLLASGRADLFRGQTFDWARLIPSLFRLTEEKRKFAYEELRLFSEWANGVPQMRNYHGNDDAITAIAQHYGIATSFLDVTTDPRVALAFAKSERAASDDDAVIYCFLEGALRHIEGIKIVKISVENLWRLEVQSGLFLDYITDSIVDAVKSMAIKIHFPRALRSAAETRRLYPLRKSALESVLDQWFYKRQIEGALDQFVPHVKNQVVVRRQTYPGIFRWREIPELTPEWLSKDLRWVQPPIESVRITGRPLDLKIRLQVSDPLRDAKNLRELILPAICEAFAAGRLLSFDFELSGVGKRYSKRISQIANWVWDGIRVLPYKISELASAMANMLTILSHVSKRTKHSSNLAQILFGETDIIEVAPVGGHIEAGFVSKSDLDVARNYAGGRGFTKYSLKMLTESPDILNDFITDPWLLFDFLKFKRIFIEQFVPTAIIGFWENWVDDKDEISKLRWSVPFNPALLGYVSRFQYRFSSPLAAERDVSRLVLINNDMDKDDISESFLFCMPHIMGGGGPFLLKLHGYGHDARPIWEIPDAVQRAVWIFDIGGISVLEVSSSLNSASTDDEIHADGLGAFEVWLIAKGLMEEVNGKSLGEIRPIYESFWRDLSVSNKKMEKYYKEALGREMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
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        <name evidence="6" type="ordered locus">AZC_0290</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
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            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
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        <property type="gene ID" value="AZC_0290"/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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    <sequence length="88" mass="9525" checksum="F05F090A13CC6AA3" modified="2007-12-04" version="1">MNTEKINETNIPMTPEALAVLGGGEIAYLRTIKSEDAQRLFPQAPEMQPGLTLFTLHAADGTPIMLTDSREAALANAFQNELTTVSVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK84</accession>
    <name>A8IK84_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">argH</name>
        <name evidence="8" type="ordered locus">AZC_3873</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3873"/>
    <dbReference type="EnsemblBacteria" id="BAF89871">
        <property type="protein sequence ID" value="BAF89871"/>
        <property type="gene ID" value="AZC_3873"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3873"/>
    <dbReference type="eggNOG" id="COG0165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_3_4_5"/>
    <dbReference type="OMA" id="GYYLANV"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="62"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="374"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="504" mass="55724" checksum="26ABCF6957204BF3" modified="2007-12-04" version="1">MMIESEAHRSKVSRRLQDETAQEICDFIYLPRLADFARGFPYLTAINQAHILMLDAQALIPSDAAKTLAEALLQMEENGPSAIALDPQREDAYFNYEAHLIGKVGLDIGGRAHTARSRNDILATMDRMRCRDLVIALLDALAELRQTAAEQAARYVDVVMPGYTHLQPAQPMTYGFYLAGVAEALERDAERLAGAYGRVDRCPLGAGAFAGTPYGIDRSETARLLGFPAVVDSTLDAVASRDFIFEVLGSLSILAATWSRIAQDYFLWSTDEFRFIEFPDSVAGTSSIMPQKKNPIVLEFLKGKAGHIIGHYAGAVSILRATNFTHSGDANRESISFFWGAADDCLTSLKLLRLIIRTASPRREVMLKRARENFSSATDLADAIVMKSGLSFRQAHHIVGAVVRDALDHDLTADRISLDMVQRACRDQMGREIALSEEDVHASLDPRISVASRRDGGPAEEGVRMVLGKVQAKLDADRQDNRRRREVIDAACRDRRRLMEELAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL35</accession>
    <name>A8IL35_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3983</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3983"/>
    <dbReference type="EnsemblBacteria" id="BAF89981">
        <property type="protein sequence ID" value="BAF89981"/>
        <property type="gene ID" value="AZC_3983"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3983"/>
    <dbReference type="eggNOG" id="COG1565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024840_3_0_5"/>
    <dbReference type="OMA" id="YYHPQRN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PTHR12049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="367" mass="39116" checksum="D5BE2C09EF22FC91" modified="2007-12-04" version="1">MTNPLKDEIRALIEVEGPISVGRYMALCLGHPRHGYYVTRDPFGAGGDFITAPEISQMFGELIGLWAVACWQQMGEPSSFRLVELGPGRGTLMADALRAARLVPAFGAAMRLHLVEMSPVLRRRQAETLKDHAPQWHDRIEDVPEGPAIVIANEFFDALPVDQFVRGPTGWHERRVGLDVTGSLVFGLDPRPFRPIEAFAAGFPRPAEGDLLERMESGPARALAARLAAQGGTALALDYGHARSGFGDTLQAMKDHRFTNPLAEPGEADLTAHVDFAALAGMARAAGARAFGPLTQGDFLRRLGIEARAATLMGSASAAQKAAIGSALTRLTGAGTGEMGTLFKVLALAAPTFGPPPAFAPEEEFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMC4</accession>
    <name>A8IMC4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="6">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mesJ</name>
        <name evidence="6" type="synonym">tilS</name>
        <name evidence="8" type="ordered locus">AZC_0527</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0527"/>
    <dbReference type="EnsemblBacteria" id="BAF86525">
        <property type="protein sequence ID" value="BAF86525"/>
        <property type="gene ID" value="AZC_0527"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0527"/>
    <dbReference type="eggNOG" id="COG0037">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018869_3_2_5"/>
    <dbReference type="OMA" id="PWQDPHN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="7">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="2"/>
            <end position="7"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="332" mass="35149" checksum="19BB1550946296AF" modified="2007-12-04" version="1">MSGGPDSTAMLVLARIWRYGLLDGPSFFVATVDHGLRPEATDEALAVGALCEELGLPHVILPWRGPKPRSGIQEAARDERFALLRSFARQNGLDGLALAHTQDDQAETVLFRLCRGSGIGGLAAMRPVSRRNGLAVLRPFLSIAKARLVATLAVSGTPFVRDPSNEDTRYARPRLRAISPLLGAEGLDAARLAVLAQRAARADDALEAATDAAQKLLVHGGWDDEAGTRLDAEGFFRLPQEIALRLLMRALTLRATEGPVELAKAERLLEALRAAVIQPGRLRRTLAGALVTLKQGSLSIVQAPARQAGAAHLAANSGTSGALVLGKEGGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMI0</accession>
    <name>A8IMI0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0556</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0065 (bug) family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF86554">
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        <property type="gene ID" value="AZC_0556"/>
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    <dbReference type="KEGG" id="azc:AZC_0556"/>
    <dbReference type="eggNOG" id="COG3181">
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    </dbReference>
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        <property type="entry name" value="TctC"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006987"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
    <sequence length="360" mass="38410" checksum="AABC5473300276B5" modified="2007-12-04" version="1">MFSFGRSVRERGKGTASARPKRNGCPMAGHLRRISACLLLGLLLWAGLDVRLGETAVRAQDFPKRAITLVVPRPAGGMSERLAELLAPPLSRAFGVPVNIRLMPGDMGGEGARYVVAAPADGYTLMVAPSTLLLFDPTTLPNLGFVPERDLDPVLLAIRMPTVLVVQPAVEARSLSELEAEIRAKPDLVFGASAKGSINDLLAAEMFRRARMPRNITYLGGGGAVEAALLKGQVQASFQEASISADDIDRALVRALAITGDERSPRLPGVPTFAELGAPEMNVFTWQAVVAPAGLKEDVRAALENGLKTALLDRTVVTAMQAIGAEVVAAGSRQLSRVLTEERVRWRELGTADPYSATTR</sequence>
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    <accession>A8IMJ2</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF86561">
        <property type="protein sequence ID" value="BAF86561"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="ABC_TroCD"/>
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        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC-3"/>
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        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="20"/>
            <end position="40"/>
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    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
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        <source>
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    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="290" mass="29784" checksum="909CDE46A5302556" modified="2007-12-04" version="1">MTPYDLLVSPFVEFEFMRRALVGIFALSLGAGPVGVFLMLRRMSLTGDAMAHAILPGAAIGFLVSGLDLAAMTIGGLAAGLLVAVGAGVVARATEIKEDASMAAFYLVSLALGVMIVSLKGSNVDLLHVLFGTVLGLDDPTLLLVAGIASLTLVTLAFIWRPLVLECVDPTFLASVSRAGGVSHIIFLALVVMNLVGGFHALGTLLSVGLMMLPAATARFWVRDLTALVVVATVIAFVAGVAGLLISYYVGAPSGPAIILVAGAAYAVSVVFGPAGGVLSRLMPRRHLEA</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    </evidence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <location>
            <begin position="1"/>
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        <location>
            <begin position="1"/>
            <end position="16"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89745.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="438753.AZC_0657"/>
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        <location>
            <begin position="185"/>
            <end position="201"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <sequence length="201" mass="20366" checksum="1220C7581D6C4F09" modified="2007-12-04" version="1">MAIQPPSDIVLDVMQAADPAKAQKVTANLQRLATSASSGVFDTMVQGVAGGFSGGLSFASTSTTSLHNLTNLSKRPGAEPGEAASELMAKAGNDPLRKFEAMVLSTFVESMLPKSTAVYGAGNAGNVWRSMLAQKMGDQVAEAGGIGIAKTIAARHPEMRTVSGAQVAGAPTAAAARLTTVQPSGGEADKDTTTTGTDISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQ93</accession>
    <name>A8IQ93_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-isomer specific 2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169289.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0758"/>
    <dbReference type="EnsemblBacteria" id="BAF86756">
        <property type="protein sequence ID" value="BAF86756"/>
        <property type="gene ID" value="AZC_0758"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0758"/>
    <dbReference type="eggNOG" id="COG1052">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019796_1_3_5"/>
    <dbReference type="OMA" id="TAYYTDH"/>
    <dbReference type="OrthoDB" id="1638924at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh_C" evidence="2">
        <location>
            <begin position="110"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="304" mass="32362" checksum="B0CA7600B4CB338B" modified="2007-12-04" version="1">MRAVFVDASPTLAGVAERLHRADDIPLGIHRNPDVTPAELPAVLDGAEIAIIDHTALPTDIARTCNGLKHVVFLGTGARSYMNPEELAALGISVHIIKGYGDTAVAECAFALMWAAAKGFAYMDRGVRAGKWLRTDGVELTGKTIGLIGYGGIGAEMARLAKGAGMRVIAWNRTPKDEPGVTFVPLETLLAESDVVSLHLLLNDETRGFLSRERLAQLKPGVILVNTARGALIDEEALVEALKFGNVRHAGLDVFVTEPLPADHPFTALENVTLSAHSAFRTPEASDNLIEAALNHCRRIAAGG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1991-02-01" modified="2022-05-25" version="115" xmlns="http://uniprot.org/uniprot">
    <accession>P20669</accession>
    <accession>A8INU9</accession>
    <name>NODD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Nodulation protein D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">nodD</name>
        <name type="ordered locus">AZC_3792</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1990" name="J. Bacteriol." volume="172" first="2658" last="2666">
            <title>Identification and characterization of a functional nodD gene in Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Goethals K."/>
                <person name="van den Eede G."/>
                <person name="van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
            <dbReference type="PubMed" id="2158977"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text>NodD regulates the expression of the nodABCFE genes which encode other nodulation proteins. NodD is also a negative regulator of its own expression. Binds flavonoids as inducers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="Z48959">
        <property type="protein sequence ID" value="CAA88827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="M60872">
        <property type="protein sequence ID" value="AAA26190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="A35268">
        <property type="entry name" value="A35268"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P20669"/>
    <dbReference type="SMR" id="P20669"/>
    <dbReference type="STRING" id="438753.AZC_3792"/>
    <dbReference type="EnsemblBacteria" id="BAF89790">
        <property type="protein sequence ID" value="BAF89790"/>
        <property type="gene ID" value="AZC_3792"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3792"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_39_0_5"/>
    <dbReference type="OMA" id="CARPHVM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08462">
        <property type="entry name" value="PBP2_NodD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037416">
        <property type="entry name" value="NodD_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0010">Activator</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0536">Nodulation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <feature type="chain" id="PRO_0000105699" description="Nodulation protein D">
        <location>
            <begin position="1"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="HTH lysR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; AAA26190/CAA88827." evidence="2" ref="1">
        <original>A</original>
        <variation>T</variation>
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="314" mass="35551" checksum="046F300CC7D4D61A" modified="2008-02-26" version="2">MRFKGLDLNLLVALNALLSEHSVTSAAKSINLSQPAMSAAVQRLRIYFNDDLFTINGRERVFTARAESLAPAVRDILSRIQSTIIKGDLFEADRSERVFRIISSDYSTSIFIRGVISAASTSLPLLRFELISPDDNCHDLLNKSEVDALIMPEIFMSSAHPFVPLFEEKMVCVGCARNHEDRNISSIQEYLSMRHVVAKFGRGMRPSLEEWFMAENGMRRRIDIVVQSFSMIPPVIQGTERIAIMPYRLVEHFSKFMPLKVFALPFPLPRFTECLQWPSIATPDLGNRWLRAYLADHASQMMILDSAEYSGASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQP9</accession>
    <name>A8HQP9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alkyl hydroperoxide reductase C</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peroxiredoxin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Thioredoxin peroxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_1051</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
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            <dbReference type="ChEBI" id="CHEBI:57783"/>
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        <text evidence="3">Homodimer.</text>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="AZC_1164"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1164"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="41"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="121" mass="11667" checksum="F3204AC6E3D29065" modified="2007-12-04" version="1">MTRATFQTSRPALLAGALLIGLWLSGPVPGLSGQAFAAETTKTGGAGCEADTSGHAATPPSQGASSGTAAGNVGSTGWTNGMGGTHIGTSNHAPTPGSPQSQPETVTGANPGSPDQPNKPC</sequence>
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        <name evidence="1" type="ordered locus">AZC_4166</name>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
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    <reference evidence="2" key="2">
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <sequence length="336" mass="35690" checksum="8B713BF9E9FA46EA" modified="2007-12-04" version="1">MEAQSTRESSAQVGATATALWYVGPQRADVRTETLPRRGEGELLVETRWSALSRGTERLVFAGLVGPDHSERMRAPMQDGEFPFPVKYGYCAVGRVVEGPQRFLGRHVFVLHPHQDRFIVQADDVLPIPETVPPRRATLAANMETALNALWDSGAGAGDRIVVVGVGLVGLLITYLAAQLPGAEVTAVDPDPARGAIAGSFGAHFAACTQAVREADVVFHTSASSEGLCAALSCCATEASLVEVSWYGDKAVTVGLGGSFHAKRLRLISSQVGAVPAARAPRWPHKRRLAKALDLLADPRLDALITEDVAFADLPGALARILGDDPQGVATVVRYA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90191">
        <property type="protein sequence ID" value="BAF90191"/>
        <property type="gene ID" value="AZC_4193"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4193"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1977012_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721147" evidence="1">
        <location>
            <begin position="31"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="126" mass="13981" checksum="8AD6F98575B83C39" modified="2007-12-04" version="1">MLGCQRHIGRDRPMRRSVALLCLMPLGAQAGDLTFYEKSIASAADCHKTYEQVVPDWRRNRAALFTRFPDGRERLIHCLPDGVAEWICVPAAGKIYTAVQIGKTLAACEAQTPRVPVLDKPSMFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSV5</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4222</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90220.1"/>
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    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4222"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="167"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90220.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="275" mass="29122" checksum="DCCEAC241E586BC8" modified="2007-12-04" version="1">MGRTRLVTGLVAFILTFALGGAASLLLVSQFKTTVEETARRDVSVIGGSLARALAQQFEKAARFGIPLKLLPGVESYLAQTLTQTPGITRIVVRGPDGREVRSAIGPTTGTDTVSAPIQVDGLSVGLVEVTTSPTSFSAGIDDTEWRMLGAVAGCALMSGLLAAWLAGGALNRRRQRFVTALERNLDGDLDPGPYSAAIGRSSVARAFHALSMEARRIGAKVTAFQAYAEELLAVDFDGQLRPEVERIRREALPAPVHLPTTTDDTLSPQPKRGA</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT26</accession>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Backer P.D."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <sequence length="317" mass="33446" checksum="B88B6F2BE6E38FF7" modified="2007-12-04" version="1">MRWWPYWSVSDYVKAYMVDHFTAIYSKRNDNPNFTRCFSIWHKYGARFGAFAGNDVPGMVAGPTSKAKFVACDFDNGTTPIYVDPGTDGTTATFTECSLQGRDANFTGEPLVHVRGSNTKLTIIGGNLKEAGVALVRVADGGTGNTVRMLEVETGRWNIAAGASGDALVASSGNAIYVDGKIQQQVEMAIGANIYWPDGPFKPYTPTVTASSGTITAYTASAKYKIVNRQIEIYYDILLTTAGSATGDMVVTLPVSTTAPGAGFGSETTLTGKGVNMRQGAAASTFTISFAADNGSIFNSGGAGDGRHIIGKFVGPV</sequence>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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    <gene>
        <name evidence="1" type="primary">rpoB</name>
        <name type="ordered locus">AZC_0887</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169418.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HTY8"/>
    <dbReference type="SMR" id="A8HTY8"/>
    <dbReference type="STRING" id="438753.AZC_0887"/>
    <dbReference type="PRIDE" id="A8HTY8"/>
    <dbReference type="EnsemblBacteria" id="BAF86885">
        <property type="protein sequence ID" value="BAF86885"/>
        <property type="gene ID" value="AZC_0887"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0887"/>
    <dbReference type="eggNOG" id="COG0085">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000524_4_3_5"/>
    <dbReference type="OMA" id="FMTWEGY"/>
    <dbReference type="OrthoDB" id="9601at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02013">
        <property type="entry name" value="rpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000329164" description="DNA-directed RNA polymerase subunit beta">
        <location>
            <begin position="1"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1357"/>
            <end position="1376"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="1376" mass="153145" checksum="6F0DB9146C095872" modified="2007-12-04" version="1">MAQTFTGRKRIRKFFGKIKEVAEMPNLIEVQKASYDQFLQIEEPKGGRADDGLQAVFKSVFPISDFSGAAMLEFVRYEFEPPKYDVDECRQRGMTFAAPLKVTLRLIVFDVDPDTGAKSVKDIKEQDVYTGDIPLMTMNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARIIPYRGSWLDIEFDAKDIVYARIDRRRKIPVTSLLFALGLDSEEILNTFYEKILYTRAKDGWRMPFDPKRMKGYKAVADLIDADTGEVVVEAGKKLTVRAARQLVEKGLKALKISDDEMVGQYIGEDIVNVHTGEIYAEAGEEITEKVLKTLGDAGFDEIPVLDIDHINTGAYIRNTLSADKNSSREEALFDIYRVMRPGEPPTLDSAQAMFHSLFFDAERYDLSAVGRVKMNMRLDLDAEDTVRILRREDILAVIKTLVELRDGKGEIDDIDHLGNRRVRSVGELMENQYRVGLLRMERAIKERMSSVDIDTVMPQDLINAKPVAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIEAPYRRVVDGRVTDEVVYLSAMEEGKYYVAQANVPLDTDGRFQEDLVICRHAGDVLVVSPDRVDFMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRSQAPLVGTGMEAVVARDSGAAIAARRAGVIDQVDATRIVIRATGETDPSKSGVDIYRLMKFQRSNQSTCINQRPLVRVGDVVKKGDIIADGPSTELGELALGRNVLVAFMPWNGYNYEDSILLSENIVKEDVFTSIHIEEFEAMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVRAGDILVGKITPKGESPMTPEEKLLRAIFGEKAADVRDTSLRLPPGTTGTIVEVRVFNRHGVDKDERALAIEREEIERLAKDRDDEQAILDRNVYGRLSEMLVGKVAIAGPKAFKKDTEITKDALGEYPRSQWWLFAVADDALMSELEAIRAQYDESKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPVEDMPFLEDGTNVDIVLNPLGVPSRMNVGQILETHLGWACAGLGRQVAAAVDAYYGSKDQQVLRNALVKVYGPDDIEVLDEKQITELGENLRKGVPMATPVFDGAHEADIEEHLEKAGLNPSGQSTLFDGRTGEPFDRKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGEDTFESGIPESFNVLVKEMRSLGLNVELLNSKTGRQTNPGTRENLPAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU04</accession>
    <name>A8HU04_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0892</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0892"/>
    <dbReference type="EnsemblBacteria" id="BAF86890">
        <property type="protein sequence ID" value="BAF86890"/>
        <property type="gene ID" value="AZC_0892"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0892"/>
    <dbReference type="eggNOG" id="COG1409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052611_0_0_5"/>
    <dbReference type="OMA" id="NHDAYVR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="25"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="322" mass="34458" checksum="E350FAE41D1D5310" modified="2007-12-04" version="1">MRFNLSGPCSKEAAPSEGSRRMFVLAHLSDPHLGPIPEARLSELLGKRFFGMMNWIGARRRNFGASTLAPLMADLAAQAPDHIAVTGDLVNVSLPAEFDTGATFLASLGTPDKVSVIPGNHDAYVRSAMTYHLERWAPFLAGDETHPGTPVDTEAFPYVRRRGPIAIVGVSTAIPTAVFLASGKAGKAQLERLRALLRQLKAEGLFRVVLIHHPPVGERHSHRDLRDAPAVRAALVEAGAELVLHGHDHRASLGHIEGVAPPIPVVGVPSASAGPEDGRGAGRYNLYRISGGPGAWVCDMESRGYAKGETDVALRDQRRLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU37</accession>
    <name>A8HU37_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0903</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169434.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0903"/>
    <dbReference type="EnsemblBacteria" id="BAF86901">
        <property type="protein sequence ID" value="BAF86901"/>
        <property type="gene ID" value="AZC_0903"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0903"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_661692_0_0_5"/>
    <dbReference type="OMA" id="EFMVELA"/>
    <dbReference type="OrthoDB" id="741829at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721173" evidence="2">
        <location>
            <begin position="33"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="410" mass="42612" checksum="AD0940FC184C7A8B" modified="2007-12-04" version="1">MLPGAVVKVLSRVAGALALVSLLAGLPKAARAEPALSMDEVIGRTRGWTIGLSTGMGGCMATATYEDRTTVWMGFGGGSNKAFFALSNPKWRSLAVGNRYELQLLARGEGRWRGRFTGVELDKEMGLLAQDLVTGFVIDIARAGALDVVYDRKIIAQLSLSGSMAAIDALVDCQKSVIASLRTEPKAGDGARTKARGEGPQSEGGKSSGTGFFVSERGHLLTNNHVVNGCKKVTVTPVGEVAVPAQVVARDPNNDLALLKADLTPKDVPALNTRVRVGDGVSVYGFPLSGLLASNGNFTIGNVTATAGLADDTRMVQISAPVQPGNSGGPVIDQKGNIVGVVVSKLDALGVASAIKDVPQNVNFAIKSSIAQNFLDTNGIESKAKLKDATLEPAAVADVAKGFTVRIECE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU86</accession>
    <name>A8HU86_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Carbonic anhydrase</fullName>
            <ecNumber evidence="3">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0918</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169449.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0918"/>
    <dbReference type="EnsemblBacteria" id="BAF86916">
        <property type="protein sequence ID" value="BAF86916"/>
        <property type="gene ID" value="AZC_0918"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0918"/>
    <dbReference type="eggNOG" id="COG0288">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053879_4_2_5"/>
    <dbReference type="OMA" id="MHTITSE"/>
    <dbReference type="OrthoDB" id="1841447at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="245" mass="25406" checksum="0E2D763D6B69F91D" modified="2007-12-04" version="1">MCELCTTNGLSRRHLLGGGMAVAGLAAAGLLGGLATPTAALAQAARPNDIPPAEALKRLKDGNARYAANKPRQHDFSAGRAARASAQYPFAAILSCADSRVAPELAFDQGPGELFVCRVAGNFVNEDGLASLEYGVQVLGLPLIMVLGHTNCGAIDATIKVVKDNITLPGHLPGLVNALKPGIEAAIAKQPKDLLATAIEENVRFNVRRLRDASPILSKAVADKKLQVVGGVYEIGTGKVTAIEA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUG2</accession>
    <name>GCH1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="1">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP cyclohydrolase I</fullName>
            <shortName evidence="1">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">folE</name>
        <name type="ordered locus">AZC_0942</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169473.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HUG2"/>
    <dbReference type="SMR" id="A8HUG2"/>
    <dbReference type="STRING" id="438753.AZC_0942"/>
    <dbReference type="EnsemblBacteria" id="BAF86940">
        <property type="protein sequence ID" value="BAF86940"/>
        <property type="gene ID" value="AZC_0942"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0942"/>
    <dbReference type="eggNOG" id="COG0302">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049768_3_1_5"/>
    <dbReference type="OMA" id="CEHMCMS"/>
    <dbReference type="OrthoDB" id="1632367at2"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000071759" description="GTP cyclohydrolase 1">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <sequence length="218" mass="24539" checksum="E5FAD4BB3D92CDE6" modified="2007-12-04" version="1">MDAVVKLFKEQAETEAQRQMPVHRPVDAPRPSRAEAEAAVRTLLAYIGEDPHREGLQETPARVIRSYDEIYGGYALSPDDVLDRTFGEIGSFDDFVLLKDIPFTSHCEHHMVPFMGKAHVAYFPVERVVGLSKIARLVDLYARRLQTQEHLTSQITTALDEALKPRGVAVMIEAEHMCMSMRGILKPGVTTLTSQFTGAFRDDPAEQVRFITMLRGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVP3</accession>
    <name>A8HVP3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_4340</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4340"/>
    <dbReference type="EnsemblBacteria" id="BAF90338">
        <property type="protein sequence ID" value="BAF90338"/>
        <property type="gene ID" value="AZC_4340"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4340"/>
    <dbReference type="eggNOG" id="COG0685">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025841_0_0_5"/>
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        <source>
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        <source>
            <dbReference type="RuleBase" id="RU003862"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="305" mass="32780" checksum="6F5EF90D2B355EBA" modified="2007-12-04" version="1">MMSGPVRASRELGKAPVSVSFEFFPPKTEEMERTLWASIDRLAPLCPNFVSVTYGAGGSTRERTHSTVARIVKETSLAPAAHLTCVAATRAEIDEVVRSYADAGVKHIVALRGDPTTGVGTKYEPHPGGYAYAADLVAGIKKLGDFEVSVSAYPERHPESPDADADIDVLARKVDAGANRAITQFFFDNDVYFRYLDKVRARGIDIPIVPGILPVTNFKQAARFAAATGASVPDWFAARFEGLDDDPETRKLIAAAVAAEQVMDLVDRGATDIHFYTLNRADLVYAVCHLLGLRAQAAAAPATAA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <location>
            <begin position="58"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90344.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="264" mass="28684" checksum="79F20ABB8F519818" modified="2007-12-04" version="1">MTASSAASHPAYQGHEGLVSAHFSPQAQAYVASEVHAKGADLADLAARLSGAGVDRLLDLGCGGGHVSFTAAPLVRHVMAYDLSSSMLQAVVDEAQGRGLDNIATEQGRAEDLPFADASFDWVVSRYSAHHWHDLGAGLRQARRVVKPQGKVIFMDVVAPPHPLFDTFVQSIELLRDTSHVRDYSVPEWVSAAEKAGLVLEGMETRRLRLEFASWIARMRTPPVLADAIRALEEGAPKEVRAYFEIEPDGTFTLDTATLVFRPL</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <property type="evidence" value="ECO:0007669"/>
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    </evidence>
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    <sequence length="334" mass="36285" checksum="B52A0CC720A5C07D" modified="2007-12-04" version="1">MPKSDALLTKSDVAHERTIVTPSGSRTFGFLLLPDFALLTYASAIEPLRAANALSGQDLYRWRHISVDGQPVKASNGVAIAVDERVGETLALDALVAVAGGNPARFRHKATFTFLRRLAHRGVMLAGISGGPYALARAGVLAGHRCTLHWEHIPAFTEEFPDLDVKRTLYEIDRDRVTCAGGIATLDMMADLIARDHGPGLANAVSEWFLRTQARPASGAQRMAPRERFGIGNAKVLSVLAEMEARLEEPATRQELAALAGISLRQLERLFADHLGETLGAHYLRVRLDRARSLLKQTALPVAEVAMACGFVSTSHFSRAYKARFGASPKGERV</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF87501.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF87501">
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    </dbReference>
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        <location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50943"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87501.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="249" mass="26836" checksum="08ED058A90AA213D" modified="2007-12-04" version="1">MAPTRAAVCSASDSLVIPARKGGRPKKDMRVPDRRSKAAKDETETASYITGSGAPAAGATSLEQALGIQVRSIRRQLDLTVSDLANAAGISVGMLSKIENGQISPSLSTLQSVARALNVPITALFSTFEERHDCSYVKAGQGVVIERRGTKVGHQYELLGHGLGGDIVVEPYLITLTQEAVPYTSFRHGGVEFIHMLSGEVVYRHGDRTYHLRPGDSLMFDSAAAHGPEELITRPMTYLSIIVYSRQAE</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To bacterial alkanal monooxygenase alpha and beta chains.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170052.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1524"/>
    <dbReference type="EnsemblBacteria" id="BAF87522">
        <property type="protein sequence ID" value="BAF87522"/>
        <property type="gene ID" value="AZC_1524"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1524"/>
    <dbReference type="eggNOG" id="COG2141">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027853_9_1_5"/>
    <dbReference type="OMA" id="APGSDQM"/>
    <dbReference type="OrthoDB" id="1003376at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019949">
        <property type="entry name" value="Luciferase_OxRdatse_group-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03558">
        <property type="entry name" value="oxido_grp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="17"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="334" mass="36100" checksum="55EDF55FC9C6D9B3" modified="2007-12-04" version="1">MTKLSILDLAPIPQGATARDALQRSLDLAQHAEGWGYNRFWVAEHHNMVGIASAATSVVIGYLADGTRKIRVGAGGIMLPNHSPLVIAEQFGTLEALYPGRIDLGLGRAPGTDQWTMRALRRDPRAADTFPQDVLELQALLGPAQPDQRLRAVPGTGAEVPLWILGSSLFGAQLAGMLGLPYAFASHFAPELLIQALDTYRARFEPSRQLQKPHAMVGVPVVVAETDAEARRLFTSTQQSFTHMFRGTRGQLPPPIDDIETYWTPMEKVQVQGMLGRAIVGGPATVETGLKALIAETQADELMVASAIFDHSARLRSYEILSTLDIAAPVPALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXX9</accession>
    <name>A8HXX9_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1552</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170080.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1552"/>
    <dbReference type="EnsemblBacteria" id="BAF87550">
        <property type="protein sequence ID" value="BAF87550"/>
        <property type="gene ID" value="AZC_1552"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1552"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_1_5"/>
    <dbReference type="OMA" id="TRWIDSA"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="94"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="294" mass="31144" checksum="7D8CB4E673ECF54E" modified="2007-12-04" version="1">MTATDTALQAAPAQKARGYWATVGRRLTRDKVSMVCALILLAILLAALLAPYLHLADPYQGSMVRRLRHIGTPGYPLGTDELGRDMLSRLIYGGRLSLLIGILPVVLAFIIGTSLGLVAGYAGGWLNTAIMRTVDVFYAFPSVLLAIAISGVLGAGIVNSIVSLTVVFVPQITRVAESVTTGVRNLDFVDAARASGAGALTIMRVHMLGNVLGPIFVYSTGLISVSMILAAGLSFLGLGTKPPEPEWGLMLNTLRTAIYVNPWVAAMPGVMIFAVSICFNLLSDGLRSAMDIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYE0</accession>
    <name>A8HYE0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1604</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="567"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="9">
        <location>
            <begin position="218"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF90530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="631" mass="65925" checksum="382AFF232D21BEC5" modified="2007-12-04" version="1">MAGAPSLHGHGGTPSAASPPLSRVGAAALAVERVLGALVEIPVAILVAAEIIVLFMGVVARYVFHTPIVWSDELASILFLWLAMLGAVVAFRRGEHMRMTAVAAKVNPGLRAFLDVLAMTAALAFILLVFPHALEYAEEEVFILTPALEIPNAVRAAALPVGLGLMIAFAVLRLVRHTDLKVVGVALLTTVAVIAAFWLLGPFLRPLGNANLLIFFVGVVAACVFAGVPIAFAFGLATFGYLALTTRTPMMVLVGRMDEGMSHLILLSVPLFVFLGALIEMTGMAKAMVRFLASLLGHVRGGLHYVLVGAMYLVSGISGSKAADMAAVAPVLFPEMKQRGAKEGDLVALLSATGAQTETIPPSLVLITIGSVTGVSISALFTGGMVPGIVLAVTLCAVVWWRYRGEKLDHVKRATGGEILRSFVIAFPAIALPFVIRAAVIEGVATATEVSTLGIVYAIAAGILIYRQFDVRRLMPMLVDTASLSGAILLIIGTATGMAWGLTQSGFSRELAAAMTGLPGGAMTFMAVSIVAFIILGSVLEGIPAIVLFGPLLFPIARAVGIHEVHYAMVVILAMGIGLFAPPFGVGYYAACAIGRVDPVAGMKPILGYLVALFVGLIAVALVPWFSIGFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ60</accession>
    <name>A8HZ60_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ordered locus">AZC_4542</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173061.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4542"/>
    <dbReference type="EnsemblBacteria" id="BAF90540">
        <property type="protein sequence ID" value="BAF90540"/>
        <property type="gene ID" value="AZC_4542"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4542"/>
    <dbReference type="eggNOG" id="COG0770">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031507_4_1_5"/>
    <dbReference type="OMA" id="VEMGANH"/>
    <dbReference type="OrthoDB" id="1861122at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="111"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="335"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="113"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF90540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="476" mass="49474" checksum="FC97E8488943F426" modified="2007-12-04" version="1">MTTRALYTPEEILAATGGTARGTLADVTGISIDTRTLEPGDAFFAITGENSDGHAYVAKALENGASLAVVAADRVQGLPDGPLVVVPDVLGALTDLGKAARARSEARIVAVTGSVGKTTTKEALRIALSADGETHASAASYNNHWGVPLSLARFPRSARYGVFEVGMNHPGEITPLVRMVRPHVAVITTVEAVHIAQFSGIEEIADAKAEIFDGLEPGGTAVLNRDNPLFDRLVASARAKGVKNIVSFGADPACEVRLKDVVLHPACSTVVADVLGTPVTFKLGMPGRHIVQNALAVLAAVRLLGGDLALAAVALARLRPPPGRGVPVSLSVSGGTATLLDESYNANPASMRAAIDVLSRTPVGPRGRRIAVLGDMLELGTEGAQHHRELAEALEAGKIDRVFCAGPLMHALWEVLPSSRKGGYAVHASHLEPLISAAIRAGDTLMVKGSNGSRMGPLVKALAERFRLPGDALLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ79</accession>
    <name>A8HZ79_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_4550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutaredoxin]-dithiol + arsenate + glutathione + H(+) = arsenite + glutathionyl-S-S-[glutaredoxin] + H2O</text>
            <dbReference type="Rhea" id="RHEA:22016"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:17668"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29242"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:48597"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:146199"/>
            <dbReference type="EC" id="1.20.4.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the ArsC family.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4550"/>
    <dbReference type="EnsemblBacteria" id="BAF90548">
        <property type="protein sequence ID" value="BAF90548"/>
        <property type="gene ID" value="AZC_4550"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4550"/>
    <dbReference type="eggNOG" id="COG1393">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116644_0_0_5"/>
    <dbReference type="OMA" id="YLKHPPD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="151" mass="16373" checksum="8FEF3C7261A4AF76" modified="2007-12-04" version="1">MRQGMQDAWEVGSTMSDFPVTIYHNPACGTSRNTLAMIRAAGYAPTVVEYLKTGWTQDQLKGLISAMGGTARDILREKGTPAAELGLLVPEVSEADLLAAMVAHPILVNRPIVVTPLGTRLCRPSERVLDLLERKPDSFTKEDGEVVALKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ91</accession>
    <name>A8HZ91_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">murG</name>
        <name evidence="13" type="ordered locus">AZC_4555</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173074.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4555"/>
    <dbReference type="CAZy" id="GT28">
        <property type="family name" value="Glycosyltransferase Family 28"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90553">
        <property type="protein sequence ID" value="BAF90553"/>
        <property type="gene ID" value="AZC_4555"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4555"/>
    <dbReference type="eggNOG" id="COG0707">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037404_2_1_5"/>
    <dbReference type="OMA" id="AADMMLC"/>
    <dbReference type="OrthoDB" id="1165736at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="5"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="188"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF90553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="367" mass="37609" checksum="9CF9CE9F7A7B2C74" modified="2007-12-04" version="1">MSKLVLLAAGGTGGHLFPAEALAAALAARGFTIDLATDSRAARYAGHFPARELHVLSADTVRGRSPVALAKTALALGGGFLSALMLLRRIKPAVVVGFGGYPTVPPLMAASLTGVPSLVHEANGVMGRANRLLASRVKAIATGFPGILDSDPALKAKAVWTGNPLRPAVLEVTRIPYAPPTAEGPLNLLVFGGSQGARVMSDIVPEGLAQLDPALRPRLRIVQQARAEDLDRVQGTYAQAGITAEVAPFFNDLPARMAAAQLVISRSGASTVAELSALGRPSLLVPLPGAIDQDQAANAKALAATGGALPIPQAEFTPERVAREITRLAAAPQTLTQMADAARSAGVLDAADRLADLVARLAGSPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZV3</accession>
    <name>A8HZV3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173150.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4631"/>
    <dbReference type="EnsemblBacteria" id="BAF90629">
        <property type="protein sequence ID" value="BAF90629"/>
        <property type="gene ID" value="AZC_4631"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4631"/>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009912_5_1_5"/>
    <dbReference type="OMA" id="ERYEMAQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="204"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="341"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="497" mass="55213" checksum="A0DA2DBF79C17B51" modified="2007-12-04" version="1">MFETASDTFAYVAQVAWRRRFLAIIPILLLPPLALVAAAIAPARYEARMTLLVQEPSKLNPILNDIAVNPNLKERMSALIALAHSEVVLGKVLEDLHRVTPETPPKQRDDLVKALSEAVTIQLVGSDIIEMRVRSMDPNSPAQTLQALSRRFVERLVSPERTAVQDSERFLKDQMSERRRALDGAEKALLDFRTANADKLPALYNSTVQRLATLEQQLQSKEMDLSIAGATMEELRKRLASTNPLIGRIEENIVQASAELASLRARYTDEHSLVQAAEWRLQRLEEERRHLLNDSHAISTTDLDRLWNIAAGVGTAPAGDQRGNDSDRNATPLLVSQLQRLQEQQSKRTAIESEVDQLRKVIAVLQRDIAEFGPIDQQQQQLERQVSFARDNYESLAKRYEMARVTGALGVFEAPERVKVLETPSDPASKVTPGYALYVLAGIISGFAVGGALAAASELLDTRLRRPADFARILGVPVIARVPRISPQEAQPRPYAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1V7</accession>
    <name>PURA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenylosuccinate synthetase</fullName>
            <shortName evidence="1">AMPSase</shortName>
            <shortName evidence="1">AdSS</shortName>
            <ecNumber evidence="1">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purA</name>
        <name type="ordered locus">AZC_4670</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAF90668" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90668.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_043879832.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I1V7"/>
    <dbReference type="SMR" id="A8I1V7"/>
    <dbReference type="STRING" id="438753.AZC_4670"/>
    <dbReference type="EnsemblBacteria" id="BAF90668">
        <property type="protein sequence ID" value="BAF90668"/>
        <property type="gene ID" value="AZC_4670"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4670"/>
    <dbReference type="eggNOG" id="COG0104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029848_0_0_5"/>
    <dbReference type="OrthoDB" id="232152at2"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000336999" description="Adenylosuccinate synthetase">
        <location>
            <begin position="1"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
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        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
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    <feature type="binding site" evidence="1">
        <location>
            <begin position="299"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>substrate</name>
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        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="331"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="413"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="430" mass="46513" checksum="189F74955F4F19FC" modified="2008-05-20" version="2">MANVVVVGSQWGDEGKGKIVDWLSEQADVVVRFQGGHNAGHTLVVDGVTYKLSLLPSGVVRPGKLSVIGNGVVLDPQALVDELARLESQGVHVGPDRLRIAENTPLILPLHRELDALRENASEGTRIGTTKRGIGPAYEDKVGRRAIRLVDLVDPKALPAKVERLLTHHNLIRRGLGVEEVNPQALVDELLALAPKVLPYMDRVWELLDKARKDGKKILFEGAQGALLDIDHGTYPYVTSSNTVASSAAGGSGVGPGALDYVLGITKAYTTRVGEGPFPTELTDEVGKTLGTKGREFGVVTGRPRRCGWFDAVLVRQTVRTCGIHGIALTKLDVLDGFDEIKVCVGYKLDGKEIDYFPSEMGAQARVEPIYETIEGWTDSTAGARSWADLPAEAVKYVRWLEELIGCPVAVLSTSPERNDTILVHNPFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I278</accession>
    <name>A8I278_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15 16">Protoporphyrinogen IX oxidase</fullName>
            <shortName evidence="15">PPO</shortName>
            <ecNumber evidence="15 16">1.3.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">AZC_4716</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16">Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>3 A + protoporphyrinogen IX = 3 AH2 + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:62000"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15 16">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 15 16">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cell membrane</location>
            <topology evidence="3 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15 16">Belongs to the HemJ family.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.-" evidence="15 16"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4716"/>
    <dbReference type="EnsemblBacteria" id="BAF90714">
        <property type="protein sequence ID" value="BAF90714"/>
        <property type="gene ID" value="AZC_4716"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4716"/>
    <dbReference type="eggNOG" id="COG1981">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125006_1_0_5"/>
    <dbReference type="OMA" id="VRLFIYH"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070818">
        <property type="term" value="F:protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02239">
        <property type="entry name" value="HemJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005265">
        <property type="entry name" value="HemJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40255">
        <property type="entry name" value="PTHR40255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03653">
        <property type="entry name" value="UPF0093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004638">
        <property type="entry name" value="UCP004638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00701">
        <property type="entry name" value="TIGR00701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 16" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 15 16" id="KW-0349">Heme</keyword>
    <keyword evidence="13 15 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR004638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="BAF90714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="173" mass="19663" checksum="7821F906C8E7F1A9" modified="2007-12-04" version="1">MAQPLPFRGSVACGFLWALGNAAAPRSHGWNQRMYEWIKALHIMAVISWMAAMLYLPRLFVYHADAETGSVQSETFKVMERRLLKGICNPAMIVTWLAGIYLIYEGGWIRSGWLHGKLALVLLLSAFHGFIVRWWKAFAADKNVHSSRFFRMVNEIPALLMVGIVLLVVLKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2C3</accession>
    <name>A8I2C3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin-dependent monooxygenase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">TetX monooxygenase</fullName>
            <shortName evidence="1">TetX</shortName>
            <ecNumber evidence="1">1.14.13.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a tetracycline + H(+) + NADPH + O2 = an 11a-hydroxytetracycline + H2O + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:61444"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:144644"/>
            <dbReference type="ChEBI" id="CHEBI:144645"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aromatic-ring hydroxylase family. TetX subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170378.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1850"/>
    <dbReference type="EnsemblBacteria" id="BAF87848">
        <property type="protein sequence ID" value="BAF87848"/>
        <property type="gene ID" value="AZC_1850"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1850"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009665_4_0_5"/>
    <dbReference type="OMA" id="DRPIFAL"/>
    <dbReference type="OrthoDB" id="504558at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00845">
        <property type="entry name" value="TetX_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043683">
        <property type="entry name" value="TetX_monooxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1 3" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="2"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="FAD_binding_3" evidence="2">
        <location>
            <begin position="290"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="379" mass="39697" checksum="1C8FCECE4C181D14" modified="2007-12-04" version="1">MRTPVTIIGAGLGGLTLARVLQMQGVTATIYEAEASPDARPQGGLLDMHADSGQRALRAAGLFEAFLRLVRPAEDAKRIVDKTGRILFDKPGTACGERPEVDRGDLRRLLIASLAPQTIRWGHRVVSVVGRDGGRHEVTFANDATVMSELLVGADGAWSKVRPRLSDVQPAYTGTSFIETLLPAGTSRHAASAELIGSGTLMALAPGRGILAHRNADGTLHAYIALNEAEDWFRALDFSDPSGALAHVAACFEGWAPPLTALIGEGRQAPILRPIHALPVGLRWPRMPGVTLLGDAAHLMSPFAGAGANLAMLDGAELARAILASPDDTEAALAIYEAGLFPRSAAVAATSARNLACFFGETAPQGVADLFAGEVAGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2K2</accession>
    <name>A8I2K2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1889</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1889"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87887">
        <property type="protein sequence ID" value="BAF87887"/>
        <property type="gene ID" value="AZC_1889"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1889"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_374562_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="50"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="741" mass="81298" checksum="EBF80877B0821D8B" modified="2007-12-04" version="1">MRPRLRRGVEVRGEWWPRKGLQHSMSAHQGGPDGADVKMSSSETRPMRATIAIPLHNHAPWIGKQLDSLFAQWRADFELLVVDDGSEDGGIDVVMDRLAARPDIVATVLRHGRSRSSALVDAFARYASAPVIIQADSDDITLPGRLDAILACFDRDPRCRLVSSNAVLISEGGMPMGILDAIHGDRVVGRDDPVPVYWGALWYGATLAYHRSVFEAFPPMDAEFCPYGFDTIAPARATLLGTHHLLARPLVGWRQHVNNTHRRVGALGTSASAREHYAALDVMIKAQVVRDAQWLRERSAPEDQPRISAAIERCEQQFMAYFDKWARLRNRRDQAGGQAAVSDGTTDRPLPDMPPVVTLPVARSWPVERYTPLAQALSRWPGFHEAEESHIWTSRQVVAVLRVTAPDAVALALTLGSSLSLPTARALVSINAGPEIEVALPQSGCCVVEVPLRSREDHLLPWTGVSLLSIRVPLADAPINKVPDHPDTRILGAALYAIEPIVTQQAEVPHLGQLMTRMWAEQDDWKLEPGCLTPIAGWLSEREMRLLYGCARLLEGPFLEMGAWVGRATSVLARGVRDAGGEKRFVSAEIGPELEHFRAIGDEVHYFSPQCDGQSIGHVAASVFEAEIAPVLRGDGGVIGTLARNLDALALLPFVTIHEGDFATAPDLGYRFIFNDCAHTPAEIERSAAGLKALIGERTIIMAAHDHSPEAEATFRALFDVLESMCVDTLFVCRMRNRPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2U1</accession>
    <name>A8I2U1_AZOC5</name>
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        <submittedName>
            <fullName evidence="4">Silent information regulator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170462.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1935"/>
    <dbReference type="EnsemblBacteria" id="BAF87933">
        <property type="protein sequence ID" value="BAF87933"/>
        <property type="gene ID" value="AZC_1935"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1935"/>
    <dbReference type="eggNOG" id="COG0846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023643_3_0_5"/>
    <dbReference type="OMA" id="EQCKKCR"/>
    <dbReference type="OrthoDB" id="1264438at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="12"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="253" mass="27302" checksum="3C48D5937D397AC9" modified="2007-12-04" version="1">MIFEADLKTAQRELADFLTAADRAVAFTGAGLSTECGIPDFRSPGGLWSRNKPIAFGDFRAHPAARNEAWRRKFVMDASFAGAQPGRGHRALANLLAQGRLSGIITQNIDGLHQASGVPDMDLVELHGNGTYATCLDCRRRYELGWVKTRFEAAGGIAPDCEACGGPIKSATISFGQAMPEREMARAAALTDTCDLFIVLGSSLVVYPAAGFPLMARRNGARLVIVNRQPTDFDEMADLVVRDDIGDVLEPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2W7</accession>
    <name>A8I2W7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative N-carbamyl-L-amino acid amidohydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1947</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1947"/>
    <dbReference type="EnsemblBacteria" id="BAF87945">
        <property type="protein sequence ID" value="BAF87945"/>
        <property type="gene ID" value="AZC_1947"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1947"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024588_2_1_5"/>
    <dbReference type="OMA" id="MGSHIDT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="429" mass="46360" checksum="434D1214A9E7A909" modified="2007-12-04" version="1">MAGRHSRSLTGSKVRQMHRHANLRPNMDRLWSTLARSAEIGTTARGGLRRLALTAEDGEVRRVFQRWCEEAGCQLTVDGIGNMFAVRPGQEADGKVVLVGSHLDTQIKGGRFDGILGVLAGLEVIRTLNDHGIETRLPVAVVNWTNEEGARFEPPMIGSAIFTGDKSLDFALSRTDKDGITLGAALDAISFRGTGGLRPDQCDSLFELHIEQGPRLDAAKIQLGVVTGAFAVRGFVVEVIGETGHVGPTPMPDRHNALVGAAHVTLAIEEIGWELHPTGGKSTTMRLVAEPNLLGILPDRVEMTCDMRHPDNAVVSQALERFIARLPELEAKSRCKIRLHEGWSYGGMAFDRDRVGLVRGAAEALGYTHMDMLTEAGHDAMHVANHLPTAMIFTPCEGGLSHNELENVTLADIEPGVNVLLQAVLARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A8I444</accession>
    <name>A8I444_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lipoprotein-releasing system ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lolD</name>
        <name evidence="6" type="ordered locus">AZC_1688</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170216.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1688"/>
    <dbReference type="EnsemblBacteria" id="BAF87686">
        <property type="protein sequence ID" value="BAF87686"/>
        <property type="gene ID" value="AZC_1688"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1688"/>
    <dbReference type="eggNOG" id="COG1136">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="FVYQSHR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="11"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="232" mass="25113" checksum="A78ECB010DAEF3BC" modified="2007-12-04" version="1">MMPEPDFPPALALVNVARRYKEGEGAIEVLRDANLVVEPGQSVALVAPSGTGKSTLLHLAGLLEHPDEGEVYVDGAPTSGLPDKERTRLRRIHVGFVYQFHHLLPELTALENVMMPQMIRGLSKKEASVRAADLLDYLGLGKRLNHRPSELSGGEQQRVAIARALANAPRLVLADEPTGNLDPKTSDHVFGALAELVHATGVAAIIATHNLDLADRMDRRVTLRDGQVVELA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-10-14" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4G3</accession>
    <name>PIMT_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="1">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pcm</name>
        <name type="ordered locus">AZC_1728</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAF87726" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87726.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_043879119.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I4G3"/>
    <dbReference type="SMR" id="A8I4G3"/>
    <dbReference type="STRING" id="438753.AZC_1728"/>
    <dbReference type="EnsemblBacteria" id="BAF87726">
        <property type="protein sequence ID" value="BAF87726"/>
        <property type="gene ID" value="AZC_1728"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1728"/>
    <dbReference type="eggNOG" id="COG2518">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055432_2_0_5"/>
    <dbReference type="OrthoDB" id="1948290at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000351817" description="Protein-L-isoaspartate O-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="217" mass="23290" checksum="C0C46F51834F694B" modified="2008-10-14" version="2">MTDSEAERAERAAFILSLRRRGIRDLAVLRALELVPRGLFVDPTLRRHAYEDVALPIACGQTMSQPSLVALMTEALALNAEHTVLEIGTGSGYQAAVLSHLAAQVVTMDRYRALVGEAQTRFQVLGLRNVAAFVGDGTQGLPGRAPYDRIMITAATGEVPRALVDQLKPGGVLIAPIGAPREVQKLRRFIKDGGNLEASDLMDVRFVPLVAGVAALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4Q4</accession>
    <name>A8I4Q4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1759</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1759"/>
    <dbReference type="EnsemblBacteria" id="BAF87757">
        <property type="protein sequence ID" value="BAF87757"/>
        <property type="gene ID" value="AZC_1759"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1759"/>
    <dbReference type="eggNOG" id="COG0559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027416_1_0_5"/>
    <dbReference type="OMA" id="FGPTNRE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017779">
        <property type="entry name" value="ABC_UrtB_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <evidence type="ECO:0000313" key="2">
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    <sequence length="253" mass="26268" checksum="9367F964BCD17386" modified="2007-12-04" version="1">MSEPKKRVLVTGGGRGLGSAIVRALAAQGFAVTFTYRSAGAEAEALIAAITADLPDAEVSARAVDLADRAAVEALAEELENGETFYGFCHNAGASYDTLAAMVDQDKAEAVMQVNHFAFVRLSRALVRPMTRAREGRIVAIGSVAALQANPGNVAYAASKAALLAHVRGLAVESAKRGVTVNYIAPGFIDTAMLAKFADHRARLESQIPAGRFAQPDDVAQVAAFLFSPGASYITGAVIPVDGGLTATLAAHR</sequence>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_2415"/>
    <dbReference type="EnsemblBacteria" id="BAF88413">
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        <property type="gene ID" value="AZC_2415"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2415"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2972">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="WFTNLKL"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:transmembrane signaling receptor activity"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="233"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="320"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="479"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
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            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="583" mass="61379" checksum="ECB849993BF12E68" modified="2007-12-04" version="1">MIAALRYGRDGANAGPLQGEGNGDMKIQDVRIAYKITLILILAGVITLAAVAYLNGRTSAIIERYAYLTENQEPALLALVRANIRTNNWEAGLMTSIAYEKPDFETILKTVTSYKAEIDKILAEAARLDPENADFYRRYGQSFEQPYNEVVRGIKLAQAGNIAEARAIAQTAVPQIAAVRRSSTPVIDKAGKVILETSNDLKADTSSARLLSYVLIGGSTVLAIVVGFLLAQFSIARPIHRLGELMHRVADGDLSVTIVGQDRKDEVGGMAKALAVFREKAERAVEMEGRQKEMEQAAQQRRKTELGELASLFESAIGGIVTTVSASTDRLEGAAATLSQTATTTRSLSGEVASASDLATANVKSVAVAAEELSSSVAEIARQVQSSSEIAAEAVTQAQRTDTRIGELSQAARRIGDVVELINAIASQTNLLALNATIEAARAGDAGKGFAVVASEVKELATQTAKATGEIGDQITQIQTATADCVSAMKEIGDTINRIAGIAQAIAAAVEQQGAATLEISRNIQQAAAGTEQVSANIAQVTRGAAETGEASGAVLDSARALSNEGEHLKAEVDRFLATVRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8I734</accession>
    <name>A8I734_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2074</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170601.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2074"/>
    <dbReference type="MEROPS" id="M20.001"/>
    <dbReference type="EnsemblBacteria" id="BAF88072">
        <property type="protein sequence ID" value="BAF88072"/>
        <property type="gene ID" value="AZC_2074"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2074"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_7_0_5"/>
    <dbReference type="OMA" id="HADTVWP"/>
    <dbReference type="OrthoDB" id="1015417at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017150">
        <property type="entry name" value="Pept_M20_glutamate_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037238">
        <property type="entry name" value="Carboxypeptidase_G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="182"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="377" mass="40256" checksum="FC51D9DB5A661B15" modified="2007-12-04" version="1">MDLSALPFDTTSMLARLRPWIECESPTYDPAAVSRAVALAARDAAAAGGQVDHIPGPDGLGDCARIRFPHRDAGTPGILVMGHFDTVHPIGTLEKLAFRQEGNLCWGPGLLDMKGGTFTALEALIQLTRAGIETPLPITFLFTSDEEIGSPGTRTLIEEEAKTHKYVLVPEPGLADKGVTTGRYAIARYKLTAYGRASHAGATLKEGRSAIREMARRIPEIEDMTSDDCTFSVGVVHGGQWVNCVATTCSGEALSMAKRQEDLDRGTTRILALNERREDGTGFEVKTSVVRPVWEPNAGSMALHALAKSIAGELGFDLPHRSSPGGSDGNFTGALGIPTLDSLGPCGGDYHTLNEHIRIDTLAERGRLIAGLMARLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7K7</accession>
    <name>A8I7K7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2133</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    <sequence length="208" mass="23074" checksum="A89F37C2FEFE19AC" modified="2007-12-04" version="1">MDGVIEMGGNRYMTDPQGHLVPVDLVKPQDALEDQTVRKIIRYADDLSAQIARFRGHTFDDVASFVSILAERYGATRGGAKGNTTLTSFDGCLKVVVQVQDVLTFGPELQVAKAIVDECVAAWSDGAPAEVRALVQHAFQTDREGRINRAALFSLRRLKIEREPWPRAMAALDDAIRVVGSREYVRFYRRANARAKWEPITIDLASAA</sequence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Binnewies T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2202"/>
    <dbReference type="EnsemblBacteria" id="BAF88200">
        <property type="protein sequence ID" value="BAF88200"/>
        <property type="gene ID" value="AZC_2202"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2202"/>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010186_7_0_5"/>
    <dbReference type="OMA" id="GKPLMHG"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="186"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="412" mass="42661" checksum="D09744EA4DF14A36" modified="2007-12-04" version="1">MNMTGTPKKAPLMPVADALALITRDLDVLATEMVPVAEAVGRVLAAPLAARRSQPGADMSAMDGYAFAYPDTLDIPLTLKVVGESAAGRAFDGAVRPGEATRIFTGGVVPPGADTVVIQENTTREGDSVTITVPLAKGRNVRKAGFDFAAGTALLPAGRRLNARDVMLAAAADHASLPVVRRPRVGIIQTGDELVYPGQATGLLSEVVVSNVYGLAALAREAGAEVIDLGLVRDGMDETRAAISRARDLGIDVLVSSGGASVGEHDLMAPALKAEGIALAVHKIALRPGKPLMFGAGGNMRALGLPGNPVSAYVCAVLFLLPILSRLQGEDAPLMATRPARLGTAMPANDTRMDFVRARLSFEDGKAIAHPLTNQDSSMLSALASADCLLIRPAHAPEAKVGDPCEIIPLNA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I836</accession>
    <name>TRPC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="1">IGPS</shortName>
            <ecNumber evidence="1">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trpC</name>
        <name type="ordered locus">AZC_2205</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrpC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170732.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I836"/>
    <dbReference type="SMR" id="A8I836"/>
    <dbReference type="STRING" id="438753.AZC_2205"/>
    <dbReference type="EnsemblBacteria" id="BAF88203">
        <property type="protein sequence ID" value="BAF88203"/>
        <property type="gene ID" value="AZC_2205"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2205"/>
    <dbReference type="eggNOG" id="COG0134">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034247_2_0_5"/>
    <dbReference type="OMA" id="RGPHDLI"/>
    <dbReference type="OrthoDB" id="1789381at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="chain" id="PRO_1000071431" description="Indole-3-glycerol phosphate synthase">
        <location>
            <begin position="1"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <sequence length="263" mass="28222" checksum="1D1CAB0E44F7016C" modified="2007-12-04" version="1">MSDILSRIETYKRAEIEAARAARPQAETEAAARAADPVRPFAKALEAKIAAGQTALIAEIKKASPSKGLIRPDFDPPVLARAYEDGGAACLSILTDGPSFQGAPEYLIAARAQVSLPVLRKDFLFDTYQVAEARAWGADCILVIMAAVDDALARDLVEAATDFGMDSIIEVHDEAELDRALALPSKLIGINNRNLRTFETTLATSGRLAPRVPKDRIVIGESGIFTHADVKLLRQVGIASILVGESLMRQEDVTSATRTLLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8I850</accession>
    <name>A8I850_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Triosephosphate isomerase</fullName>
            <shortName evidence="5">TIM</shortName>
            <shortName evidence="5">TPI</shortName>
            <ecNumber evidence="5 6">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tpiA</name>
        <name evidence="7" type="ordered locus">AZC_2210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170755.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2228"/>
    <dbReference type="EnsemblBacteria" id="BAF88226">
        <property type="protein sequence ID" value="BAF88226"/>
        <property type="gene ID" value="AZC_2228"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2228"/>
    <dbReference type="eggNOG" id="COG0152">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061495_2_0_5"/>
    <dbReference type="OMA" id="EFCYKND"/>
    <dbReference type="OrthoDB" id="1345271at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01415">
        <property type="entry name" value="SAICAR_synt_PurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033934">
        <property type="entry name" value="SAICAR_synt_PurC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001636">
        <property type="entry name" value="SAICAR_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00081">
        <property type="entry name" value="purC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01057">
        <property type="entry name" value="SAICAR_SYNTHETASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="9">
        <location>
            <begin position="17"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="264" mass="30210" checksum="0133FAE074247D8A" modified="2007-12-04" version="1">MDFLNPRYTPMSRRRRIYEGKAKVLYEGPEPGTLIQHFKDDATAFNAKKHDVIDGKGVLNNRISEYIFQRLNEIGVPTHFIRRLNMREQLIREVEIIPLEIVVRNVAAGSLSTRLGIEEGTALPRSIIEFYYKNDALNDPMVSEEHVTAFGWATTQEIDDIIALAIRVNDFLTGLFLGVGIRLVDFKMECGRLWENDMMRIVVADEISPDSCRLWDIKSNDKLDKDRFRRDLGGLVEAYSEVARRLGILTDNEPNQTKGPALVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8M3</accession>
    <name>A8I8M3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2680</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171204.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2680"/>
    <dbReference type="EnsemblBacteria" id="BAF88678">
        <property type="protein sequence ID" value="BAF88678"/>
        <property type="gene ID" value="AZC_2680"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2680"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_0_5"/>
    <dbReference type="OMA" id="SVHRNQW"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="25"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="231" mass="25607" checksum="2D39EEC6FAA14F57" modified="2007-12-04" version="1">MWSQIVEEWPRFATYYNLIFIAKAAGTTLALSALGCILGSLIGLGLAVTRVTRARWLLPLRLVALVFTEVFRRVPFLVTLMLCFFAFQATGYDIPLFVVAAVSVTMIAGAFLGEIIRGGFNSVHRNQWEAAETMNFSLIDTIRLVVLPQAWRIVLPPAFGFFVMFIKDTALASQIGVIELTYVGKVLNNKGFSAALSFGVILIVYFLISYPLSRLGAHLEARLASSRHRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8P8</accession>
    <name>A8I8P8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Tripartite ATP-independent periplasmic transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2689</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2689"/>
    <dbReference type="EnsemblBacteria" id="BAF88687">
        <property type="protein sequence ID" value="BAF88687"/>
        <property type="gene ID" value="AZC_2689"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2689"/>
    <dbReference type="eggNOG" id="COG1593">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019824_4_1_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007387">
        <property type="entry name" value="TRAP_DctQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04290">
        <property type="entry name" value="DctQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00786">
        <property type="entry name" value="dctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="305"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="522"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="606"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="9">
        <location>
            <begin position="218"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="631" mass="65881" checksum="B215E5DB03B21B40" modified="2007-12-04" version="1">MIGGAMSGSLSPTAAENAAAARSAASGFGRLDAAFFGLIEHVAAAIVLVEVGVLFAGVVARYVFHAPLVWSDELASILFLWLSMLGAVVALRRGEHMRMTGCLGLAGPQTRAVLEALAILVPLGFLGLVLHPALDYASEERFIVTPALEISNVWRAAAIPVGLSLMVLACLARLARAASFKAVVIALGLTAGLMVAFYLLGPVLKPLGQINLIIFFVGVVALCVFAGVPIAFAFALATFGYLALTTRTPMLVMVGRLDEGMSHLILLAVPLFIFLGALIEMTGMAKAMIAFLASLLGHVRGGLSYVLIGAMYLVSGISGSKIADMAAIAPILFPEMKARGAKEGDLVALLSATGAQTETIPPSIVLITIGSVTGVSIAALFTGGMVPALVLGLCLCTVVWRRYRNEDLSHIRKPAWREIGKLAIVALPAIALPFVIRAAVVEGVATATEVSTIGIVYAVLAGLLIYRRFDWRRIQPMLIETASLTGAIIFIVGCATAMAWGLTQSGFSRNLAQAMAGIPGGAYGFLAVSIVAFIILGSVLEGIPAIVLFGPLLFPIAKAAGVHEVHYAMVVIFAMGIGLFAPPFGVGYYGACAISKIHPDEGLKHIWGYVAALLVGLVLVAAIPWLSIGFL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8V7</accession>
    <name>GLPK_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol kinase</fullName>
            <ecNumber evidence="1">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glycerokinase</fullName>
            <shortName evidence="1">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glpK</name>
        <name type="ordered locus">AZC_2710</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="1">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171234.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I8V7"/>
    <dbReference type="SMR" id="A8I8V7"/>
    <dbReference type="STRING" id="438753.AZC_2710"/>
    <dbReference type="PRIDE" id="A8I8V7"/>
    <dbReference type="EnsemblBacteria" id="BAF88708">
        <property type="protein sequence ID" value="BAF88708"/>
        <property type="gene ID" value="AZC_2710"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2710"/>
    <dbReference type="eggNOG" id="COG0554">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009281_2_3_5"/>
    <dbReference type="OMA" id="VQWMRDQ"/>
    <dbReference type="OrthoDB" id="233605at2"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0000250"/>
        <property type="project" value="UniProtKB"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
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        <property type="match status" value="2"/>
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        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0319">Glycerol metabolism</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000071684" description="Glycerol kinase">
        <location>
            <begin position="1"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="12"/>
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        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="1">
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            <position position="12"/>
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        <ligand>
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        <ligand>
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        <ligand>
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        </location>
        <ligand>
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    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
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    </evidence>
    <sequence length="498" mass="54639" checksum="CF9B3F28B141B183" modified="2007-12-04" version="1">MTKYVGAIDQGTTSTRFIVFDRKGQIFSVAQREHEQIYPRPGWVEHNAVEIWLNTRTVILEALEKKGLSTSDLAAVGVTNQRETALLWDRKTGEPLYNALVWQDTRTDQLVARYAKEGGQDRLRAKTGLPLATYFSGLKLHWILDNVPGARAKAEAGDALFGNIDTWLLWNLTGGPDGGIHITDVTNASRTQLMDLEKLAWDEDILKLFNIPAACLPRIVSSSERYGTGKGPLEGVTLSGILGDQQAALFGQACLHPGEAKNTYGTGNFMLMNTGEKPFPSTCGLITTVGYKLGDAKAVYALEGSIAITGALVQWLRDNLGIIKNSADIEPLARTVSDNGDVYFVPAFSGLYAPRWDDSARGVVCGLTRFANKGHIARAALEATAYQTREVLEAMVKDSKVAIRELRTDGGMVVNELLMQFQADMVNVPVVRPKVIETTALGAAYAAGLAVGYWASTDDITQNWGVDRRWHPHMAAEQREHLYGSWNKAVERSLGWAR</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
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        <property type="protein sequence ID" value="BAF88502.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2504"/>
    <dbReference type="EnsemblBacteria" id="BAF88502">
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        <property type="gene ID" value="AZC_2504"/>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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            <begin position="4"/>
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        </location>
        <ligand>
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        </ligand>
    </feature>
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            <dbReference type="ARBA" id="ARBA00005417"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="251" mass="27329" checksum="164F6CED078FEEB2" modified="2007-12-04" version="1">MGTVSMTGVSKVYGGAHGVRALDNVDVHLAEGEFMALLGPSGCGKSTLLNMLAGFEGQTEGAISFDGRSVVKPGPDRGVVFQEAALLPWLTVWQNVVFGPQVQGVPRADYEPRAKEILRVVGLDAFHDALPAQLSGGMRQRVGIARALVMQPRALLMDEPFGALDAQTRLSMQQLLLEVWQRFKTTVLFVTHDIDEAILLADRVCIMTARPGRITRDIPITLPRPRTIDDLLSPAFVAFKAQIMSEMRGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
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                <person name="D'Haeze W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <sequence length="235" mass="26074" checksum="62521C2B91732A97" modified="2007-12-04" version="1">MHKSFGAVEVLKGVSLTVERGQVVALIGRSGSGKSTLLRCINGLETIQSGRIEIAGEEVTQDKEKLRHLRTEVGIVFQSYNLFPHLSVGENIMLAPKIVKKVAAKEAHDTAREVLQLVGLSEKFDAYPDQLSGGQQQRVAIARSLAMHPKLMLFDEVTSALDPELTEEVLNVMERLARNGMTMILVTHEMGFAKRVANTTVFMHKGRIWEEGPSQELFANPQTPELRQFVKADVK</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <location>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Wiley G.B."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168578.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0047"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86045">
        <property type="protein sequence ID" value="BAF86045"/>
        <property type="gene ID" value="AZC_0047"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0047"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_34_0_5"/>
    <dbReference type="OMA" id="TSFQNGI"/>
    <dbReference type="OrthoDB" id="948440at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="254"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="466" mass="50539" checksum="AFD5EDFDCBCCE29B" modified="2007-12-04" version="1">MVSVPVAYDVTRLFLGPLSRTPRGIDRVDFGLAARLFRQSSFPCVGVMPTLHGTRAFSHHAVRRGLVRLQQLWAERQGGDKTAIWTDLVAELTGQRVGSATIPAPAPLTALQRARRMTSLLAATGFSFGNSARTHVPERAVYVNVGHISLAMPFFLRWLDARPDVTPVFMLHDVIPLDTPEYVSPSSVRHHATMVASTARHAAGLLVTTQTAQRTVRDALARIGRTDIMTLAQPLPLSRVFDTTAEPDPALAGVPYFVICGAIEPRKNHELLFNVWRGLTAELGAKAPHLVIIGSPGWKCDEILQPVRNNPQMCRHVHVASGLSSPALKRLLAGAIALLMPSHAEGFGLPLIEAMRLGVPVMASDIPAHREVVDAQALLLDPRDPLAWDAAIRHWADGGRPQVHPRSRQDTVDERETYFSGIEDFLEACAAERAKQLGPVARRTTAAGGALIGKPASAESSALDSF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGE6</accession>
    <name>THIE_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiamine-phosphate synthase</fullName>
            <shortName evidence="1">TP synthase</shortName>
            <shortName evidence="1">TPS</shortName>
            <ecNumber evidence="1">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="1">TMP pyrophosphorylase</shortName>
            <shortName evidence="1">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thiE</name>
        <name type="ordered locus">AZC_0079</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAF86077" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86077.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_043878701.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IGE6"/>
    <dbReference type="SMR" id="A8IGE6"/>
    <dbReference type="STRING" id="438753.AZC_0079"/>
    <dbReference type="EnsemblBacteria" id="BAF86077">
        <property type="protein sequence ID" value="BAF86077"/>
        <property type="gene ID" value="AZC_0079"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0079"/>
    <dbReference type="eggNOG" id="COG0352">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018272_3_2_5"/>
    <dbReference type="OrthoDB" id="1558094at2"/>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000336375" description="Thiamine-phosphate synthase">
        <location>
            <begin position="1"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="39"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="136"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="187"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="212" mass="21630" checksum="A2D17FFCFF8F1A91" modified="2008-05-20" version="2">MPHPFDLSLYLVTDRRLTAERGLLETVEEAVAGGVTLVQLRDPEAKGRALAEEARALIGLLRPKGIPLIINDRVDVAAAVGAEGVHLGQDDLDPAAARAILGPDAIIGLSVGSLEELSASNLGPVDYVGCGPINATGTKGDAGGAIGIEGFAFLRSHIALPMVGIGGLKAEDAEAVMQAGANGIAVVSALCAAPDVTEAARTLKTIIETSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGI6</accession>
    <name>A8IGI6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Exodeoxyribonuclease III protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0093</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF86091">
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        <property type="gene ID" value="AZC_0093"/>
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    <dbReference type="eggNOG" id="COG0708">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="term" value="F:exodeoxyribonuclease III activity"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="AP_endonuc_1"/>
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        <property type="entry name" value="AP_endonuclease_F1_BS"/>
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    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
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    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037493">
        <property type="entry name" value="ExoIII-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43250">
        <property type="entry name" value="PTHR43250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="22"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="290" mass="32055" checksum="79BC9A6003A1B6B7" modified="2007-12-04" version="1">MAGILTCLLLPPAVAALSLTVCTWNINSVRIRLDIVKETVERLKPDVLCLQETKCQDDKFPLAAIRELGFPHIALNGQKGWHGVATFSKRPFDAIEKQEFCGKGDARHIAVTLGGAGGLSAPVTIHNFYIPAGGDEPNPEVNPKFAHKLAFLDEAIAWEKLTEAGRPAGAHAILVGDLNIAPLETDVWNHKQLLSVVSHTPVEVDLLTRFQAAGPWIDVMREFVPPTEKLFTWWSYRSPDHTVNDRGRRLDHVWTSRSLAGKAKAMTVLKEARSWEKPSDHVPVAVTFEV</sequence>
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        <name evidence="9" type="ordered locus">AZC_0126</name>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168657.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0126"/>
    <dbReference type="EnsemblBacteria" id="BAF86124">
        <property type="protein sequence ID" value="BAF86124"/>
        <property type="gene ID" value="AZC_0126"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0126"/>
    <dbReference type="eggNOG" id="COG2204">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_0_5_5"/>
    <dbReference type="OMA" id="HSNRCHG"/>
    <dbReference type="OrthoDB" id="123059at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
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    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
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        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
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    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="145"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
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        <source>
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            <dbReference type="PROSITE" id="PS50110"/>
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        <source>
            <dbReference type="EMBL" id="BAF86124.1"/>
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    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="442" mass="48803" checksum="D45AD46B68305D83" modified="2007-12-04" version="1">MPDLKVLIVEDDEDVRLGCLQALELEGLTVIGAKCVEQVPRMAPQDFPGVVVTDIRMPGMDGMAYLRQLVEADADLPVILITGHGDVATAVQAMRDGAYDFIQKPFSPEQLVGVVQRALEKRRLTMEVRALRRQVAAIGGLESRIVGRSAAVVELRALVQDLAATPTDVMILGETGCGKELIARCLHDLSGRTGPFVALNCGGLPETLFESEIFGHEAGAFSGAAKQRIGKVEHAQRGTLFLDEIESMPMAMQVKFLRVLQERVVERLGSNRLIPVDFRVIAATKADLGALSEEGKFRADLHFRLNVATIDLPPLRDRREDIPLLFQYFVSQAALRLDRPAPEIRDSHIRELMAHKWRGNVRELRNEAERYVLGLKSSIGQGASDTPAPLSQTVEVFERGIIAEELRRQHGNISRAAEALRIAKTTLFDKIRKYGIETAPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGV6</accession>
    <name>A8IGV6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_0140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168671.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0140"/>
    <dbReference type="EnsemblBacteria" id="BAF86138">
        <property type="protein sequence ID" value="BAF86138"/>
        <property type="gene ID" value="AZC_0140"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0140"/>
    <dbReference type="eggNOG" id="COG2816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037162_0_4_5"/>
    <dbReference type="OMA" id="LEDCRWF"/>
    <dbReference type="OrthoDB" id="1435118at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000210">
        <property type="term" value="F:NAD+ diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015376">
        <property type="entry name" value="Znr_NADH_PPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09297">
        <property type="entry name" value="zf-NADH-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="8">
        <location>
            <begin position="172"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="312" mass="33595" checksum="E181430531545B07" modified="2007-12-04" version="1">MLASSSSPLGPWPALGYVGNPLDRAAQRRGEADALARRSDAQAYLLGGELVALKAGKGEVHGPLFSLPEAQDWGGSEPLFLGLEDGAPRFGLFFPVENRERMEAAGLIVTDLRSIAVGGLVEARHLGPIACAKALGAWHQRHRFCSNCGAPTRVVEAGWRRDCPSCGGQHFPRTDPVAIMLTYSGDKCLLGRQPRFAPNMWSCLAGFVEPGETFEEAVRRETFEEAGITTGKVAYHSAQPWPFPMSLMIGCLAEATSTDIVIDPLELEAARWFDRAEAAAMLTRTHPDGLFAPPPVAIAHHLIRAFVEGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGW7</accession>
    <name>A8IGW7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein AZC_0144</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0144</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86142.1"/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0183"/>
    <dbReference type="EnsemblBacteria" id="BAF86181">
        <property type="protein sequence ID" value="BAF86181"/>
        <property type="gene ID" value="AZC_0183"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0183"/>
    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_5"/>
    <dbReference type="OMA" id="RCWIAMA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="48"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="80"/>
            <end position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="309" mass="32909" checksum="D812FA4DFF703CF0" modified="2007-12-04" version="1">MSYWPLRPIRRRSARKAGSGGAAGMRSVGVETAVGAAGAEGEPGDDGLRTRCLQVAYGRRLVIDGVSLSVPSGRLTALIGPNGSGKSTLLGAMARLLAPRAGAVLLDGRSVHHMPTRALARALGILPQSPVVPESLTAYELVSRGRYPHQGALKRWSESDEQAVVRAMRLTGTLDFADVPVDRLSGGQRQRCWIAMTMAQETPVILLDEPTTFLDLRYQVEVLELLRTLAHAHGRTVVAVLHDLNLALAYADCVVCLKEGRIHAVAQEGEPLTSETVREVYGLAVTRVSHPITGAPVFLPLPSTVGGAP</sequence>
</entry>
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    <accession>A8IHR9</accession>
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        <submittedName>
            <fullName evidence="12">ABC transporter ATP-binding protein</fullName>
        </submittedName>
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        <name evidence="12" type="ordered locus">AZC_3313</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3313"/>
    <dbReference type="EnsemblBacteria" id="BAF89311">
        <property type="protein sequence ID" value="BAF89311"/>
        <property type="gene ID" value="AZC_3313"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3313"/>
    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_84_5_5"/>
    <dbReference type="OMA" id="LANAWDT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="33"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="358"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="392"/>
            <end position="399"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF89311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="604" mass="66022" checksum="A761CF4C55A002A9" modified="2007-12-04" version="1">MSSLRRSKGSRAFRLVFGFLSAHWRRQPGVIGVIVGTIALSTLCEVLVPLYAGRLVDALVSAESAAAAARPEAGAAALHAFFTILALGAVMVVFRHIAYAGIVRLTIRMMADVAQDAFARVQRFSSDWHANSFAGSTVRKITRGMWSLDLLNDTLLVALLPSVTVLMGAAVLLAIQWPIMGAVIGGGAVLFIALTVALSVYYVAPASELSNRWDTRVGGTLADAIGCNAVVKGFGAEAREEARLDRVMGKWRARVRRTWMAHTWSGTAQLLALLALRTAIIGTGLWLWWRGQASPGEVAYMLTMYFVVHGYLRDIGYYVHNLQRSVNDMQELAEIHETAVSIADRPDAVPARIRQGRIAFEHVRFHYPGHETPLYDDLHVEIAPGERVGLVGPSGSGKTTFVKLVQRLHDVSDGRVCVDGQDVRAVTQASLRRQIAVVQQEPILFHRTLAENIAYARPEASRAEIERAAALANASGFIARLPRGYATLVGERGVKLSGGERQRVAIARAFLADAPILILDEATSSLDSESEAQIQEAMERLMEGRTTLVIAHRLSTVRTLDRLLVFDHGRIAEQGRPADLLRLDGGLYRRLHERQTLDLGLAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIG7</accession>
    <name>A8IIG7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ros/MucR family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0238"/>
    <dbReference type="EnsemblBacteria" id="BAF86236">
        <property type="protein sequence ID" value="BAF86236"/>
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    <dbReference type="KEGG" id="azc:AZC_0238"/>
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    <dbReference type="OMA" id="HIVSAYV"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ROS/MUCR_sf"/>
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        <property type="entry name" value="ROS_MUCR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05443">
        <property type="entry name" value="ROS_MUCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="157" mass="17147" checksum="DF990F669873451B" modified="2007-12-04" version="1">MDDQDSNDFLAENAAQIVSAFVAHNSISAAELPNLIQTVHATLAALTGQKPVEAAPKQLVPAVSVKRSITPDYIICLEDGLKFKSLKRHLMSKYGLTPDEYRKKWDLPYDYPMVAPNYALTRSAMAKEIGLGRAKSTPAKAPEAKDAPARKPRAKKA</sequence>
</entry>
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    <accession>A8IJB4</accession>
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        <submittedName>
            <fullName evidence="3">Cell wall-associated hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0279</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168810.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0279"/>
    <dbReference type="MEROPS" id="C40.001"/>
    <dbReference type="EnsemblBacteria" id="BAF86277">
        <property type="protein sequence ID" value="BAF86277"/>
        <property type="gene ID" value="AZC_0279"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0279"/>
    <dbReference type="eggNOG" id="COG0791">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="NAPYLWG"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
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        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041382">
        <property type="entry name" value="SH3_16"/>
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    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="157"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="284" mass="30111" checksum="D2CA240B6CACC567" modified="2007-12-04" version="1">MAELDRRLTPARPDLAASSLKGVVDASRFVEGEVRRVFADVAPLRRAPRPDAMLDTEALYGETVTAFEDDMEGWSWVQLGRDGYVGYMPTIAIGPLGPAPTHRVSAPRTFLFPGLDIKLPPVATLVTGALLHVRDVRGKFAVTDRGAVPARHILPLDAAEPDFVTVAAGLLGTPYLWGGCSSLGIDCSGLVQTSLGIAGISAPRDSDMQEAALGASIDLSGPFRRGDLLFWPGHVGIVEDAVTLLHANAFHMAVAREPLGPALLRIAEAAGPLRTVRRLENGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJL7</accession>
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            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
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    <gene>
        <name evidence="2" type="ordered locus">AZC_0325</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <location>
            <begin position="1"/>
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    <feature type="chain" id="PRO_5002723670" evidence="1">
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    <sequence length="364" mass="39480" checksum="E05BCEE171C4418D" modified="2007-12-04" version="1">MPSASGEARMTPILKTAVATAALSLALACTGSAFAQQATPPAQPPITLKAMGSFHIGGKTVDISGKPVKEVVFSPGGVPAKIDPNGTYIAGQMYVQYFIPQDQKGTVPLLLWHGGGLTGVTYETTPDGREGWLNYFLRKGWAVYNSDAVERGRSGWAQSPDIFPGEPVFLTVNGPFERFRIGDGAGSWSDDPAKRKVLPGNQFPVDSYIQFVKQNVPRWTTTDDFILDAYSQEIEKVCPCVILVHSQSGKFGFEMAQKHPDKVKALIAVEPAVTGDPKLASKLAGVPILMVYGDYIATDSRWPTIRARAMDFVKLVRDAGGSVDVINLPEKGIKGNSHLIMMDRNSDEVAGVIQNWLVEKKLTR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86400.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <sequence length="195" mass="21638" checksum="52ECFA516468A911" modified="2007-12-04" version="1">MSADRILTPHSDGKCRCPWCGTDPLYVAYHDTEWGVPERDSRALFEKLLLDGFQAGLAWITILRKRDNFRRAFDGFEPEVIAAYGPEKVAALMADAGIVRNRAKIEGAVLSARAYLDLREKGIAFSDFMWEAVDGTVQVNRPRTLKDIPAETPASRALSKKLKAAGFKFCGPTIVYAAMQACGLVDDHLAECWRA</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
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    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3931"/>
    <dbReference type="EnsemblBacteria" id="BAF89929">
        <property type="protein sequence ID" value="BAF89929"/>
        <property type="gene ID" value="AZC_3931"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3931"/>
    <dbReference type="eggNOG" id="COG0128">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024321_0_1_5"/>
    <dbReference type="OMA" id="YEDHRMA"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00104">
        <property type="entry name" value="EPSP_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="44"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="54"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="471" mass="49026" checksum="E8A3CFCE9B573210" modified="2007-12-04" version="1">MNEQPRQRRPHEAPMSQVESSPSLSAHGHGSDPKPATGLPSPGLSGKVRVPGDKSVSHRALIFGALARGETRVTGLLEGEDVLNTAKACAALGATVERTGPGQWRVEGVGVGNFKAPAAPLDFGNSGTGVRLMMGAVAGNPIQATFDGDASLRKRPMKRVLDPLAAMGVKLVEEAEGGRLPMRLEGVTDLKAFTYETPVPSAQVKSAVLLAGLAASGETVVVEREATRDHTERMLAHFGADVSVEPHGAHGRRITLKGRPELKAAPVDVPSDPSSAAFPLVAAVIVPGSDIVITDVMMNPLRTGLITTLKEMGASIETLAERTEGGETVADLRVRYSKLKGVAVPPERAPAMIDEYPILAVAAAFAEGETRMQGLAELRVKESDRLAAVADGLAACGVTHRIEGDDLIVTGAADVEGGGPVATHMDHRIAMSFLVLGLASRAGVKVDDVSFIATSFPTFMPMIAGLGAIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKS3</accession>
    <name>A8IKS3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Precorrin-4 C11-methyltransferase region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the precorrin methyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172464.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3944"/>
    <dbReference type="EnsemblBacteria" id="BAF89942">
        <property type="protein sequence ID" value="BAF89942"/>
        <property type="gene ID" value="AZC_3944"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3944"/>
    <dbReference type="eggNOG" id="COG2875">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011276_7_1_5"/>
    <dbReference type="OMA" id="WSAMGEQ"/>
    <dbReference type="OrthoDB" id="1185397at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046026">
        <property type="term" value="F:precorrin-4 C11-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11641">
        <property type="entry name" value="Precorrin-4_C11-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006362">
        <property type="entry name" value="Cbl_synth_CobM/CibF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01465">
        <property type="entry name" value="cobM_cbiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00840">
        <property type="entry name" value="SUMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="253" mass="26789" checksum="342DBB91E5A364DB" modified="2007-12-04" version="1">MTVHFIGAGPGAADLITVRGRDLIARCPVCLYAGSIVAPDLLAYCPPGARIVDTAPLDLDRIEQEYVAAHAAGQDVARLHSGDLSVYSAVAEQVRRLERRGIPYTLTPGVPAFAAAAAALRAELTVPEVAQSVVLTRVSGRASAMPEREKLATFAESGATLAIHLAIHALDRVVAELTPFYGAECPVAVVVKASWPDERILRGTLATIAAQVADDPIARTALILVGPALAPADFRESALYNVDYVRRFRGMAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKS7</accession>
    <name>A8IKS7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cobalt-precorrin-5B C(1)-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.195</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cobalt-precorrin-6A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">cbiD</name>
        <name evidence="7" type="ordered locus">AZC_3945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:26285"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:60063"/>
            <dbReference type="ChEBI" id="CHEBI:60064"/>
            <dbReference type="EC" id="2.1.1.195"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 6/10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CbiD family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.195" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3945"/>
    <dbReference type="EnsemblBacteria" id="BAF89943">
        <property type="protein sequence ID" value="BAF89943"/>
        <property type="gene ID" value="AZC_3945"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3945"/>
    <dbReference type="eggNOG" id="COG1903">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041273_0_0_5"/>
    <dbReference type="OMA" id="YHGKLIK"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043780">
        <property type="term" value="F:cobalt-precorrin-5B C1-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046140">
        <property type="term" value="P:corrin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00787">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002748">
        <property type="entry name" value="CbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036074">
        <property type="entry name" value="CbiD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35863">
        <property type="entry name" value="PTHR35863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01888">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026782">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111342">
        <property type="entry name" value="SSF111342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00312">
        <property type="entry name" value="cbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="391" mass="39300" checksum="9B68EAAB4862F773" modified="2007-12-04" version="1">MTARRLRPMKGLMSTGGKEDGPFAEQPDGAPAPNLRRGWTTGTCAAGAAKAAFAALVTGAFPDPVEVELPNGARPAFALAVSALEGDSARAGIVKDAGDDPDVTHGALVSATVRRGAPGAGVTFAAGEGVGIVTRPGLPVPPGEPAINPVPRRMIAQGIAEVAAAAGVPADVAVEISIADGARLAKKTLNPRLGIVGGLSVLGTTGVVIPFSCAAWIHSIHRGIDVARAMGLDHVAGATGSASEAAVQALHQLPETALIDMGDFVGGMLKYLRAHPVPRVTIAGGVAKMTKLAQGMLDLHSKRGSADLTALAYLAREAGASLDLADRIGSANTVAHAFDEAGAEGLPLGDLVAARAWDAAAGVIAGTGMELEIVVFDREGALMGRTGFRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKX0</accession>
    <name>A8IKX0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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    </evidence>
    <sequence length="329" mass="35007" checksum="19771BAD14DD5E75" modified="2007-12-04" version="1">MARDSAASVARPLRVGVTGIGIMGSNHARVLAELPGAELVAVADPDTAQAGRVAEVLGCQAVSDHHGLLELGLDAVIVAAPTHLHHSVALDVINAGCSVLVEKPVASTVEQGREIVAAARAKGVTLMVGHVERFNPAVQAVKKAIEGEELLSIAITRVGPFPPRMSNVGVVIDLAVHDIDLIRWFTGSDIVEVQPQTSSAMAEREDIALLQFRTASGVLAHINTNWLTPFKARTVHVATRKKYVIGDLLTRQVTECFDYRPDGSYSMRHLPVAYAEPLRTELTHFLDAVRTGGTPPVSGEEGVASLEIAISCLTERVEAAARAKVRRAG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
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    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172502.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3982"/>
    <dbReference type="EnsemblBacteria" id="BAF89980">
        <property type="protein sequence ID" value="BAF89980"/>
        <property type="gene ID" value="AZC_3982"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3982"/>
    <dbReference type="eggNOG" id="COG0682">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013386_1_0_5"/>
    <dbReference type="OMA" id="TDVPWAI"/>
    <dbReference type="OrthoDB" id="435911at2"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="271" mass="29270" checksum="E0AB9193D680CBFA" modified="2007-12-04" version="1">MIQFALPFPAIDPVLFAVGPFAVRWYALAYIAGLLIGWQLARYLVSRPALWGGTSPMQPNDLDDALFWATFGVILGGRTGYVLFYNLPFFLEHPDEIVKLWHGGMSFHGGLAGTLVALVLFARARGIRVFSLLDVAGVVAPIGLLFGRLANFINGELWGRPADVPWAMVFPTGGDVPRHPSQLYEAGLEGLALFIAMLIAVRMGALKRPGLAAGLFGIGYGIGRIVGEFFREPDPQLGFLMFGSTMGMLLSIPLVLAGAGLVIYALRRPVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILP3</accession>
    <name>A8ILP3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">leuC</name>
        <name evidence="14" type="ordered locus">AZC_4061</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172581.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4061"/>
    <dbReference type="EnsemblBacteria" id="BAF90059">
        <property type="protein sequence ID" value="BAF90059"/>
        <property type="gene ID" value="AZC_4061"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4061"/>
    <dbReference type="eggNOG" id="COG0065">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006714_3_4_5"/>
    <dbReference type="OMA" id="CNMSIEM"/>
    <dbReference type="OrthoDB" id="749418at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="13">
        <location>
            <begin position="13"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAF90059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="474" mass="50928" checksum="64B95C7AC207B6EF" modified="2007-12-04" version="1">MNAPTSGPKTLYDKIFDDHVVSRQEDGTCLLYIDRHLVHEVTSPQAFEGLRMAGRKVRAPSKTLAVVDHNVPTTDRSHGIDDPESATQVETLAENTREFGIEYYNERDIRQGIVHVIGPEQGFTLPGTTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQKKSKNMRVTVDGTLPEGVGAKDVTLAIIGSIGTAGGTGYVIEYAGDVMRQLSMEGRMTVCNMSIEGGARAGMVAPDEKAFAYLKDRPRAPKGADWDKAVAYWETLRSDEGAYFDAEVRLDGANLPPIVSWGTSPEDVVSVEGLVPDPEAIEDAVRRDAKKRALAYMGLTAGTKISDIAIDRVFIGSCTNGRIEDMRQAAQIVAGHTVNANVKAMVVPGSGLVKAQAEAEGLDKIFLAAGFEWREPGCSMCLAMNADRLSPEERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAAIAGRFVDVRTWPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILZ3</accession>
    <name>A8ILZ3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_0451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0451"/>
    <dbReference type="EnsemblBacteria" id="BAF86449">
        <property type="protein sequence ID" value="BAF86449"/>
        <property type="gene ID" value="AZC_0451"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0451"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_1_3_5"/>
    <dbReference type="OMA" id="SPVWWIC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="305" mass="33354" checksum="1F7986C645178016" modified="2007-12-04" version="1">MIDLSPGFFNAHSMSIKNLDLDLLRSFAAVAELGSISAAAQRIGRTQSAVSLQMDRLAEQLGFPVVERKGRGVALTPRGAAFLDDARRLLDLNDRVLGHHLRSGFSEPLRLGFVQDVAESALQRILARLGSLFPGAPITVRVCSTNTMIEKLRIGELDLAAGYRVETDVPTRLIMREQMCWIGARSLRLNPEEPVPLLMFESPCIFRSAAISALTAAGRSFRIALTSPSLPGVMAAVGAGLGITLRSARSLRPDLMTIGDLGTQPLPHFEYALYSRAENRLPALDQIEQVIEEELRRERPLFAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8INI7</accession>
    <name>A8INI7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative cobalt transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3756</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CbiQ family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172279.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3756"/>
    <dbReference type="EnsemblBacteria" id="BAF89754">
        <property type="protein sequence ID" value="BAF89754"/>
        <property type="gene ID" value="AZC_3756"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3756"/>
    <dbReference type="eggNOG" id="COG0619">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056469_4_2_5"/>
    <dbReference type="OMA" id="MKAQMSR"/>
    <dbReference type="OrthoDB" id="1479665at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Lee KB."/>
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    <sequence length="148" mass="16339" checksum="F3B768590152C1BD" modified="2007-12-04" version="1">MAGRTKKAQISVYLEPDVLDLLAHYAAQRDQSMSLIAQAAIASFLSPDSAERQEAALARRLGQIDRRLARLERDLGISTEAFATFIRFWLATTPALPEPAAQAARAKVSERYTAYTRALGRRLAKGPPLRREIEEDLAGTENDRGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPP0</accession>
    <name>A8IPP0_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">CheW-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cheW</name>
        <name evidence="2" type="ordered locus">AZC_0662</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169193.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0662"/>
    <dbReference type="EnsemblBacteria" id="BAF86660">
        <property type="protein sequence ID" value="BAF86660"/>
        <property type="gene ID" value="AZC_0662"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0662"/>
    <dbReference type="eggNOG" id="COG0835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048995_3_3_5"/>
    <dbReference type="OMA" id="DERLAMS"/>
    <dbReference type="OrthoDB" id="1711729at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="160" mass="17612" checksum="5BFE84C564F042B5" modified="2007-12-04" version="1">MTSTSLVLARQENTGAGAQYVTVRIGPQLFGLPIEMVHEVFVPDHITRVPLSNHEIEGVLNLRGRIVTMINMRSMLGLPALEDTRRMAVGIEHHGESFGLMIDEVGEVLVLDPARKETNPTNLDPHWADIVTGVYRLKGQLMLVLDVDLALGRLNTARAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQG5</accession>
    <name>A8IQG5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169311.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0780"/>
    <dbReference type="EnsemblBacteria" id="BAF86778">
        <property type="protein sequence ID" value="BAF86778"/>
        <property type="gene ID" value="AZC_0780"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0780"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OrthoDB" id="2018797at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
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        <property type="entry name" value="OmpA-like"/>
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    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
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    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721829" evidence="3">
        <location>
            <begin position="24"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="76"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="199" mass="21230" checksum="D6EFF4F9198FA985" modified="2007-12-04" version="1">MKSLMLRGALTAALLVSAAAPLAAQTDLSNAQIVQGLNNLTQDAPVVTAASLRQAALDHATMYSGPPSQRPPLAIQLDKLAQINVQIQFKLNSAIILPDSYATIGAIADALHNPVLQGYRFIVTGNTDTTGTREHNLKLSQERADAVVEALTTTFNVNPARLEAVGLGEEALQDTKNPESPVNRRVQIFNVGPLPPRPR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-10-01" modified="2022-05-25" version="113" xmlns="http://uniprot.org/uniprot">
    <accession>Q04855</accession>
    <accession>A8IBK7</accession>
    <name>Y3085_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein AZC_3085</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_3085</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1991" name="Mol. Gen. Genet." volume="231" first="124" last="138">
            <title>Characterization of a novel Azorhizobium caulinodans ORS571 two-component regulatory system, NtrY/NtrX, involved in nitrogen fixation and metabolism.</title>
            <authorList>
                <person name="Pawlowski K."/>
                <person name="Klosse U."/>
                <person name="de Bruijn F.J."/>
            </authorList>
            <dbReference type="PubMed" id="1661370"/>
            <dbReference type="DOI" id="10.1007/BF00293830"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="X63841">
        <property type="protein sequence ID" value="CAA45329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S18623">
        <property type="entry name" value="S18623"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171609.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q04855"/>
    <dbReference type="SMR" id="Q04855"/>
    <dbReference type="STRING" id="438753.AZC_3085"/>
    <dbReference type="PRIDE" id="Q04855"/>
    <dbReference type="EnsemblBacteria" id="BAF89083">
        <property type="protein sequence ID" value="BAF89083"/>
        <property type="gene ID" value="AZC_3085"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3085"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_20_5"/>
    <dbReference type="OMA" id="NARCARF"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000066345" description="Uncharacterized protein AZC_3085">
        <location>
            <begin position="1"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="GAF">
        <location>
            <begin position="25"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="185"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="4">
        <location>
            <begin position="263"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="342"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="1">
        <location>
            <begin position="472"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00141"/>
        </source>
    </evidence>
    <sequence length="735" mass="80476" checksum="CFF94DDF06440B9A" modified="1994-10-01" version="1">MADEAEQAGLRILGDVLSAAHSAGDLSCLSPDLLARIADTFHLQRVSLFQVHEAEGRGIAATCVIDWRRPGLAFPAMTEGSHPPLTAAGGDPLLAQWAARRRRGETIIGRTRDLTGYLYGFFSHYGVVTFLTEPVMVHGRWWGHFCVDTPDAEHEWTAVERQAFKCIAAVLAGLLARSGTEGLVSEAARRAMLDTSIDAVIVADEAGAIVEFNHAAEAIFGHTREGVIGRPMTETIIPAHYIDRHRQGFMRHLATGENHIMRRLVEVEALRADGSVFPAELTVNEHRAGGRRLFSAFVRDISDRITSRRALERLAFTDMHTGLSNRTGLLRLCTGRPTRPSGAVVLMLRDLGVVKTSFGDDWAEPMIVETANLLSRMLPQEACLGRTGESEFTVVTWQPGAAAELAETLIGRLRSAIESGGRRFYLRVGLGVVERPGDATYLLRDAEMAARDCRDGHLLHFAEHMRAQHQQRLELEMALRDVIQRRTSALSLHYQPVVSARTGGLVGFEALVRWYSETHGPVSPALFVPLAEAGGFAERLGAWVIETAISACAGWNVRRRAHGLAPWHIAINLSATEVVAPDLIERVRQTMAFHGLPPQCVCFELTESAILNQPEIAIETLSRLRALGCTTAIDDFGTGYSSLSYLQRLPMDVLKIDRSFVLDMVDNSRSREIVRVMIEMAHGLGMSVVAEGVETTGALQILRQMGCDRAQGFLFGRAMPGDVAGTLPETLAPTG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQ40</accession>
    <name>TRPF_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
            <shortName evidence="1">PRAI</shortName>
            <ecNumber evidence="1">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trpF</name>
        <name type="ordered locus">AZC_1017</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrpF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169548.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HQ40"/>
    <dbReference type="SMR" id="A8HQ40"/>
    <dbReference type="STRING" id="438753.AZC_1017"/>
    <dbReference type="EnsemblBacteria" id="BAF87015">
        <property type="protein sequence ID" value="BAF87015"/>
        <property type="gene ID" value="AZC_1017"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1017"/>
    <dbReference type="eggNOG" id="COG0135">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076364_1_1_5"/>
    <dbReference type="OMA" id="FYAKSPR"/>
    <dbReference type="OrthoDB" id="1854712at2"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="PTHR42894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="chain" id="PRO_1000071437" description="N-(5'-phosphoribosyl)anthranilate isomerase">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <sequence length="228" mass="23350" checksum="3CF37A8FA9BDF608" modified="2007-12-04" version="1">MAIEVKICGLSTAETLEAALAAGADLVGFVHFPKSPRHVPLEAAPALSRAVAGRAAKVLLLVDPDDATLAAAVAAFQPDIIQLHGKESPERVAAIRARTGRPVMKALPVSGPADLAVVPAYAAVADRLLFDAKPAPDDTLPGGNGRVFDWTLLAGLDPGRPVMLSGGLDAGNVSQALSVVRLDGVDVSSGVETAPGLKSPEKILAFVRAVKAAEAASRPSRLKKVEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQ68</accession>
    <name>A8HQ68_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative choloylglycine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1021</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    <sequence length="378" mass="40088" checksum="75E97F87E4EB0853" modified="2007-12-04" version="1">MCGLHSPCGIGGGLLMALARWKRAARAVIVAAAGYAAVDPAVACTRAMFVGTDQVVITGRNMDWPEDMRSNLWAFPKGIARDGAAGPKSIRWTSKYGSLIATAYDVGSADGMNEAGLVANMLYLTEAQYGAADDRPTLAVSLWAQYALDNYATVAEAVDAFAKDTFRVVGGTIPNGAAAQLHLALSDATGDSAILEHINGKLVIHHSRDYVVMTNSPPFDQQLALDAYWKEIGGLTFLPGTNRASDRFVRASFLIGSLAKTADPAFISAVPGQNFENQSALGVLSVMRAVSTPLGIKTPETPNVSATLWRTVSDQKNRVVYFDSATSPNSFWVPLGDLDLKPGAPVKKLTIAGGRVYGGNAAAQFEAAKPFEFLRADP</sequence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="194" mass="20774" checksum="656C9F723B29DDDB" modified="2007-12-04" version="1">MRGDNPHMTQRISGPAAEPLTLAEAKDFLRLTDPSTDVLVGALLSAARRTIESATGRVLMTQSWRLVRDAWPASGLFLLPIAPVASLDAARVRRADGTWEEVPAGRLSLLGDRTPQLIGLDRAHLPQPAVDHGGIALDVTAGYGPEPADVPSDLLQAVRLTLAHFHEHRDVVGEAIGLPGAVLALIAPYRMLRL</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    </reference>
    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <property type="component" value="Chromosome"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723879" evidence="1">
        <location>
            <begin position="19"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87140.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="235" mass="24172" checksum="9FF66203C73822F2" modified="2007-12-04" version="1">MVKGARAIAATMVMGLFAAGCQAPGGPPSWGTSVVKETDGFGDYYETVINVPAPTGAPRAFSCAGPWGPSTSDTVLKGIFGGGRAVQATDVLRPDGTTGPGTIVLPNDPQLRVSVAWADGFAYAGPIRFNFTEQSAWSVNGVRIGSTIADLERANGKPFRLVGFGGDAGGVVTDWQGGALANLPGGCNLTVQLAISALAPASAQAKVVGPKVFLSTDRNVRALKPTVGRFWVMYN</sequence>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Lee KB."/>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="419" mass="47240" checksum="178D514C9BBE5BB2" modified="2007-12-04" version="1">MLDKTDTHLEALLRRRKPGYSLEAPFYTDPDIFASDLDLIFGRHWIYVGVEPDVAEPGDAMVIDIGKTSVIITRNDDNEVRAFHNVCRHRGARVLQDYKTSVGNLVCRYHAWTYDLDGKLLFAEHMGKDFDAGCHGLKPVHIRSLEGLLFICLSDDPPADFDDMAARMAPYLAPHDLKNAKVAFESELIEPGNWKLVMENNRECYHCAGNHPELTVPLFAYGFGFAPEELDDMGRLEAQRYADLVKASHGEWESCGFPSQMIEHLDDMVTGFRTERLPLDGAGESHTGDTRAACRKLLGAINDPRHGALHFWTQPNSWHHFMSDHVVTFSAIPLDAERTLVRTKWLVHKDAVEGVDYDIANLTAVWQATNVQDAELVGLCQEGARSPAYEPGPYSPHTEMLVEKFCNWYVGRMRAQGAR</sequence>
</entry>
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        <name evidence="3" type="ordered locus">AZC_4100</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAF90098"/>
        <property type="gene ID" value="AZC_4100"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4100"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="SARPWMI"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
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        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="117" mass="12437" checksum="366EB812140BFAC6" modified="2007-12-04" version="1">MPVYDYMCEDCGPFTQMHPMSACADPQSCPDCGLLAPRAFLSAPYFAGMDSARRTAIATNERSANAPMTSSEFAAKKHGAGCSCCSGMQSRSKKSRTATAPSGAKSFPSARPWMISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSZ7</accession>
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    <reference evidence="2 3" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90235.1"/>
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    <dbReference type="STRING" id="438753.AZC_4237"/>
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        <property type="component" value="Chromosome"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720676" evidence="1">
        <location>
            <begin position="41"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90235.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="286" mass="30002" checksum="A60B3C2F491E7989" modified="2007-12-04" version="1">MPSAPHSPFALRRRVRRFGTLPWCAGLALVSILTASPVLAQDITFTATGAPQPYTIANVQPDVRGLAPGMGEAEARAALAKAYPASRIEATKATITYLSDGVAFRSRPVLTQMTAQASGPGTQEEVTLSFGLPTTGSPLLGIQRRVDFGSSAAAPQVAPLVGQLIEKYGPPSFRRGEEAAPVQSLIWVFGTGKVQPCGTKAPCPAVSATFAIGRLDSYRAAVEEKQDLLIQVDLIVQAGGRVRSFKTTLADNRGAVASYEAAQSQIVAAVDARAARQGTAPETPKF</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT51</accession>
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        <name evidence="2" type="ordered locus">AZC_4256</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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            <end position="209"/>
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    </feature>
    <evidence type="ECO:0000259" key="1">
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        <alternativeName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ATPase C chain family.</text>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Yamada M."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0833"/>
    <dbReference type="EnsemblBacteria" id="BAF86831">
        <property type="protein sequence ID" value="BAF86831"/>
        <property type="gene ID" value="AZC_0833"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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            <dbReference type="EMBL" id="BAF86831.1"/>
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    </evidence>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
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    <gene>
        <name evidence="1" type="ordered locus">AZC_0847</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169378.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0847"/>
    <dbReference type="EnsemblBacteria" id="BAF86845">
        <property type="protein sequence ID" value="BAF86845"/>
        <property type="gene ID" value="AZC_0847"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0847"/>
    <dbReference type="eggNOG" id="ENOG502ZI81">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_179973_0_0_5"/>
    <dbReference type="OMA" id="ITHANNS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="100" mass="10026" checksum="FFEAA14D5D71C9C4" modified="2007-12-04" version="1">MSLQIPALTEKDPFKLAQAIRELAVGRSNAVGTCTLTPGAALTTVAAVNCAPGSVVFLMPTTATAATATGLYAVAAAGSFTVHHDVSSATDRTFGYVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU67</accession>
    <name>A8HU67_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_0912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169443.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0912"/>
    <dbReference type="EnsemblBacteria" id="BAF86910">
        <property type="protein sequence ID" value="BAF86910"/>
        <property type="gene ID" value="AZC_0912"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0912"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_039613_2_1_5"/>
    <dbReference type="OMA" id="LTRPDCR"/>
    <dbReference type="OrthoDB" id="1102730at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="312" mass="33829" checksum="600B97F4C007F447" modified="2007-12-04" version="1">MIAWDDFRLVKAIAETRSLAGAAEVLGVNHSTVFRRLGALEALLGARLFERARTGYAPTVTGEELVRLAERMGEEITSIERRITGRDLRPSGELRVTTNDTLLVHLLTPVFASFRAAYPEIRLEIIVSNQTLNLTKRDADVAVRASDRPGDALVGRRVASIAWGVYGAAGGPDTRAFELAHMRQHNWVGFAEPIGAIKAAKWLKERAGEDRIVYRVNTLLGLAQAAAAGMGLAVLPCFIGAATPGLTRLQALDAEIDGSLWLLTHPDIKQTARVRAFMDYVGRELGKRRAILEGRDGDAAEPLGSDDVVSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUB2</accession>
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    <gene>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169457.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0926"/>
    <dbReference type="EnsemblBacteria" id="BAF86924">
        <property type="protein sequence ID" value="BAF86924"/>
        <property type="gene ID" value="AZC_0926"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0926"/>
    <dbReference type="eggNOG" id="ENOG50339T3">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="TANRTWD"/>
    <dbReference type="OrthoDB" id="1966184at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021270">
        <property type="entry name" value="DUF2849"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11011">
        <property type="entry name" value="DUF2849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="104" mass="10852" checksum="16B7779D8BF01948" modified="2007-12-04" version="1">MTSPLQQKLKITGPTVITANRLTDGIVVWLTARGDWASDLAEAAVLTTADEVLKLLATANADEANAVGAYPARVEIGTDGRPHPVNLRERIRVGGPTIALPGAA</sequence>
</entry>
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    <accession>A8HUC2</accession>
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        <submittedName>
            <fullName evidence="4">Zinc-containing alcohol dehydrogenase superfamily</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0929</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169460.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0929"/>
    <dbReference type="EnsemblBacteria" id="BAF86927">
        <property type="protein sequence ID" value="BAF86927"/>
        <property type="gene ID" value="AZC_0929"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0929"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_1_5"/>
    <dbReference type="OMA" id="LVCLGWR"/>
    <dbReference type="OrthoDB" id="1225778at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="13"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="326" mass="33966" checksum="65BE9F4DDAAE31EB" modified="2007-12-04" version="1">MTTARAVRIHSFGGPEVLQLETVELPPPAAGEVQVRQTAVGFNYIDVYQRTGIYPLPLPTGLGHEAAGIVEAVGEGVTSLKVGDRIAYINAGIGAYADRRNLPAERLVTIPDSISDEEAAAVIFKGLTAQYLLRKTYKVEPGDIVLIHAAAGGVGQIMSSWAKALGAFVIGTAGSPAKCDIAKAAGCDVAINYSQADWPEQVIAASGGRKARVVYDSVGKDTFLKSLDCVAPFGLMVLFGGASGPAPDISPELLSKKGSLYLTRASIFPRNADPADLRANAAELFAALDAGYVKPVIAARFPLGEVAAAHRTAEARTNAGAILLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVM1</accession>
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        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
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        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panB</name>
        <name evidence="9" type="ordered locus">AZC_4331</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
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        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
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            <begin position="8"/>
            <end position="9"/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <sequence length="415" mass="44550" checksum="A23A667752C3058D" modified="2007-12-04" version="1">MAACGLDFGTSNTTLGLPDGHGAVLAALEDGRDTVPSAVFYDRAGHPRIGRAAVRAYVEGEDGRLMRALKSVLGTALLDETTAVGRRRIPFRAVIGEFIATVKARAEADRGVRLDKVVMGRPVFFVDDDAAGNAKAQDALEEVAHSIGFSEVSFQYEPIAAALDYEQQVTHEELALIADIGGGTSDFSIVRLAPERRTKPDRVDDILANDGVRIGGTDFDRQLSLSIVMPLLGYRSPMKQPGRDVPSAYYFDLATWSAINRLYTPKTVREIVEVKRDAAHPALLDRLLKVIEDQRGHTLAIATEGAKIALAEEGEARLDLKEVESGLIAELDRGGLETHTATLAERVARRVGVCLEQAGLTADQIDAVFLTGGSTRLAHVRSAILAAVPNARVVDGDTFGSVGTGLALEARRRFG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
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    </evidence>
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    </evidence>
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        <source>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF87518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
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    <dbReference type="EnsemblBacteria" id="BAF87518">
        <property type="protein sequence ID" value="BAF87518"/>
        <property type="gene ID" value="AZC_1520"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1520"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_498436_0_0_5"/>
    <dbReference type="OMA" id="QIAPRRI"/>
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    <dbReference type="GO" id="GO:0016757">
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Glyco_trans_1"/>
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    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF00534"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF87518.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="546" mass="60999" checksum="2A2C054A01513972" modified="2007-12-04" version="1">MMSAFDQQEEIARLRAIVADYERKSHRSKWLIRQLIKKIRNAPRDFVMRMKNSRRKRRERAALARAVRVHIAPAVQEIDPSVSTAVTLAPPPPASACAEPRPMFFHVAPGEVADLISILERDQASSLALAHMDRFCGSREMAALVAEAAAIDPEVGSLTGHEMGYLTPFQDTEYRAVRQAMDKIPGGEFDAVVLVPFGKLGGADLVGGVLATALAGLGRTLILRTDLPDWDRPDWYPPEAPAIDISGDLAMIHRRTRALYVILQQIAPRRIFNVNSRLAFDMMVEYGARLAVTSKLYSYYFCADRDPHGNEVGYPIWYFANILPHLQTAIFDTEYLVKVLTDRYELPAEMRARMRTVYTPARMPVRESVVEKQIASSVTRERPRILWGGRLDRQKRFDLVIELAQVMPDVQFDCWGKAVLDAPPDLSSLPKNMNMHPPFADYDELPLADADGWLYTAEWDGLPTILIELGTIGMPIVASAVGGVPELIDDTTGWLVSPSEGVAGYERAIRQMLADADGRRARTAALQARVAERHAPATYLRAIEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXY2</accession>
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            <fullName evidence="8">Putative oligopeptide ABC transporter permease component</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1553"/>
    <dbReference type="EnsemblBacteria" id="BAF87551">
        <property type="protein sequence ID" value="BAF87551"/>
        <property type="gene ID" value="AZC_1553"/>
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    <dbReference type="KEGG" id="azc:AZC_1553"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="BPD_transp_1_N"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
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            <end position="29"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="306"/>
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    </feature>
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        <location>
            <begin position="95"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="317" mass="34424" checksum="B9AA898B341A9283" modified="2007-12-04" version="1">MLAYIARRIIYVIPIVLSVALVCFLLVHITPGDPLVAILPADASQELAAQLRAAYGFDRPLPVQFGLWVWKALHGDLGTSIATGRPVFSEVMRAVQNTFILACAASLIGFTLGVFFGLVAGYFRDTWLDKLATSIAVAGVSVPHYWLGMVMVIIFSVTLGWLPAVGAGPGGSSEWHWDWAHIQFLILPAVTMSVIPMGIVTRTIRALTGDILSQDFVEALRSKGLRETRVFRHVVKNAAPTAIAVMGLQLGYLLGGSILIETVFSWPGTGFLLNSAIFQRDLPLLQGTILVLALFFVFLNLVVDIAQASIDPRIKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Toyazaki H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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    <evidence type="ECO:0000259" key="1">
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    <sequence length="375" mass="41231" checksum="E993FA08762657A8" modified="2007-12-04" version="1">MSPRILIVGGSMGGLFAAVLLSRAGFDVTVTERSEHGLEGRGAGLVAQREVFDILREVGIEHVARVGVTAHERIYLDRSDRIIQTQRTPQTQLSWDVLFRTFRDLVPDARYRIKARALAVHSDPVGARVQYTDGHEETADLVIGADGIGSIVREAVSGAQSKPSYVGYATWRGLVPETQVPHLAQRQLFERFAFYEAPGSHILGYLVPGADGSTELGQRRYNWVWYRRYTPEELHGILLDIDGTHRPFSLAPGHLRPELAQTLREEAAERLPASFAAAVAAEPRPFIHAIFDYAPAHMVRGRVALMGDAAFVARPHTAMGVAKAAGDAFALREVLLRHPDLDRALAAYQAERVPVGQAIVAYGQRLGRGLLLDRA</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <sequence length="625" mass="67398" checksum="22A755B36C8E5175" modified="2007-12-04" version="1">MDAAARHASRGGADGSPGPPGSGAMANTTAGNMPWKAGGGRSRAARRGALMERLRLAAFLTDRLWRLVTARAPGAPLTLAQVVVPVPERLLIAPQDLRTGDATRATEIYAGTFAFAGKVAFLEGKTPFELEPPSREWAQVLHSFSWLRHLRAAGTTIARANARALVGDWMRDAGRARAIAADPEVTAHRVIAWLTQAPFILQDADHEFYRRFMRAIARQVRGLRKAASDAPDGYPRLIVIIALAFAGLCMSEQSRLLRAVQKRLSEELERQILADGGSITRSPGVLIELLLDLLPLRHAFAARNQPAPPALMNAIDRMMPMLRFFRHGDGSFALFHGMGHTAADELATILAYDDARGAPVANAPHSGFQRLDAKGTVVIADTGPPPPIAASMEAHASCLAFEFSSGRNRIIVNCGMSAINREVWRQVARATAAHSTAVVGDTSSCHFLHGTYLTRLAGVPIISGPRDVPVQRGAREGAILLRASHDGYADAFGVIHQRSWRLAADGSRLDGEDQFRAAEGAPSALGRTPFAVRFHLHPQVQVERLDDPSTVLLGLPNGEAWAFVAPGQQVVLEESVFLATSEGPRRTTQLVLLGTLADDPRLVWTLLRTREAQVPRPSGSRGSRG</sequence>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T.T."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
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        <property type="protein sequence ID" value="BAF87837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1839"/>
    <dbReference type="EnsemblBacteria" id="BAF87837">
        <property type="protein sequence ID" value="BAF87837"/>
        <property type="gene ID" value="AZC_1839"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1839"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="TIWFMDA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
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    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_ATPase_HisP"/>
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    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
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    </dbReference>
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        <property type="entry name" value="SSF52540"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87837.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="266" mass="29474" checksum="B1E5F5FA797D4036" modified="2007-12-04" version="1">MPCRRRALAAPTSTPENEFGWTPDQPLVRVVDVHKSFGSLEVLKGVSLDVRKGEVICIIGPSGSGKSTLIRCINALVPIDSGTIRVEGQEVNDPKLDKLALRRKVGMVFQQYNLFPHRTALQNVMMAPVHVLKQNRKEVEERARALLAKVRLQGKENAYPGQLSGGQQQRVAIARSLAMKPDVMLFDEVTAALDPETVKEVLVTIRELAEEGMTCILVTHEMGFAREVADHIYFTDKGLIVEHGPPAEFFANPKDERTKAFLGQVL</sequence>
</entry>
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            <fullName evidence="7">Putative membrane transport protein</fullName>
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        <name evidence="7" type="ordered locus">AZC_1860</name>
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    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1860"/>
    <dbReference type="EnsemblBacteria" id="BAF87858">
        <property type="protein sequence ID" value="BAF87858"/>
        <property type="gene ID" value="AZC_1860"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1860"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000960_2_7_5"/>
    <dbReference type="OMA" id="GWNFLVQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="419"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="74"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="552" mass="57882" checksum="8EDFE08AC771CC09" modified="2007-12-04" version="1">MAGLWWRRAPAAYVASAPCGTGLVRLVVVKNNNQYNLASEGTPDTAAPPGVPEAPMSVTAAAPAQLDHSEIRSILFGVMLAMLLAALDQTIVATALPTIGADLGDFESLSWVVTAYLLTSTAVTPLYGRLSDVHGRRMMMLIAISIFSVGSLACALAPNMVVLIFARGLQGLGGGGLISLAQTIIADIVSPRERGRYQGYFASVFMASSLCGPVLGGVLAQHLHWSLIFWINLPLGLAAYFMTDRQLRRLPRHERKAKVDVIGAVLMVVSTISLLLLLTWGGVRYAWDAPEILALGGAAVIFAVLFVWRLRTADEPFLPLPVLLHPVVARGTATALMTMGTLIALSINVPLYFETARGLSASQSGLALIPLMGGVVLGALLAGRALFMLEHYKRVAISGIAVAILGLLFLSLGPERPPLPLMLLVFGLMGIGIGCVLPITTVSIQNAVEPHQMGTATGTMNFFRSLGSAVLVAGFGAVLMAALGLGPGQGNLEQLIGGADQAGLASAFRIVFGCASVTLMLGLLALMSMEQKPLRTSVRKTSEEGGVVGVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I350</accession>
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            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ros/MucR family.</text>
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        <property type="protein sequence ID" value="BAF87979.1"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
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    <comment type="similarity">
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        <property type="protein sequence ID" value="BAF87988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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            <end position="38"/>
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        <location>
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            <end position="83"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="278" mass="29446" checksum="C098AC50772C0B13" modified="2007-12-04" version="1">MTRLGKLDPVTLLALPAVAYLGLVYGLPLVGLLARSLMVEGTVSLTSYTRFLSDPFSWTVIGNTLRVAAGVTLLCLFIGYPTALALARAKGAAQALILVAIILPLSVGVVVKAFAWQIVLRRDGVISQLLVGLGLWDAPQRLLFTETGLVVGAANVFVPFMILPIYSVLKLVDPRLIEAAATLGASPLYRFFHVALPLSLPGIVTGIAFVFSMATSMYVVPSLLIGDRFQTLATLTGRSFLFMRNEQLGSTTAVVLLILSVAVVVASAALSRRFGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3Q8</accession>
    <name>A8I3Q8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative cation transport P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1643</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1643"/>
    <dbReference type="EnsemblBacteria" id="BAF87641">
        <property type="protein sequence ID" value="BAF87641"/>
        <property type="gene ID" value="AZC_1643"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1643"/>
    <dbReference type="eggNOG" id="COG2217">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001771_6_3_5"/>
    <dbReference type="OMA" id="SPTWSWV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="622" mass="64132" checksum="6A4C53C2F5DE0554" modified="2007-12-04" version="1">MRGGRMDHAQESRLKTLLLLLALGALACGLAVRLGGWERAAAVVWSVGTIPVLLALLLEILRSLRRGEIGLDIVAALSMSSALLVGEALAACVVAVMYSGGTFLESFAEGRARRDMRDLLARVPRSATRHRAGALEDIPLDAITPGDRLLIRQGDVVPVDGTIASDTAFLDASALTGEALPVRLARDEAAMSGSNNAGEAFDLIATRPARDSTYAGIVRLVEEAQRSKAPMARLADQWSLGFLAVTVALAVAAWWFTGDPVRAVAVLVVATPCPLILAVPVALVAGLSRAAHFGVLIKGAGPLEAMARTRTLILDKTGTLTEGRPRIVSVLSHDGTAADDILRLAAALDQATKHPVAQAIVAAARERGLTLSVPSCVVETPGEGLSGQVEGRTVLVGGDGFVTARVGQGAARIELPAGSVLVAVGLDGRLAGHLVMADPLRAGTRDMLDGLRREGVERILLATGDRREVAESVTQGLGLDGIRAGLTPDQKVLLVLSERKRGPVMMVGDGVNDAPALAAADVGVAMGARGAAASAEAADVVLLVDRVDRLVPGIGIARGARRIAMESVVAGIGLSVIGMVAAALGHLSPVQGALIQEVIDVAVILNALRALRLSPKGKGAQA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-12-15" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I413</accession>
    <name>NUOK_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit K</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit K</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit K</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoK</name>
        <name type="ordered locus">AZC_1678</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I subunit 4L family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170206.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I413"/>
    <dbReference type="SMR" id="A8I413"/>
    <dbReference type="STRING" id="438753.AZC_1678"/>
    <dbReference type="EnsemblBacteria" id="BAF87676">
        <property type="protein sequence ID" value="BAF87676"/>
        <property type="gene ID" value="AZC_1678"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1678"/>
    <dbReference type="eggNOG" id="COG0713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144724_2_0_5"/>
    <dbReference type="OMA" id="NFVAFSY"/>
    <dbReference type="OrthoDB" id="2081663at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01456">
        <property type="entry name" value="NDH1_NuoK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001133">
        <property type="entry name" value="NADH_UbQ_OxRdtase_chain4L/K"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="entry name" value="Hydantoinase_B"/>
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        <location>
            <begin position="5"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="581" mass="60904" checksum="D1469CDB455CA1E1" modified="2007-12-04" version="1">MSPIDPVRLEVIRNALVAAAEEMSITIWRTSRSTVVREILDFSTAVFDAQGRNIAQSARIPVHLNSMSDCLKTILEQYIPLESWNEGDVIVTNDPYAGGQHLPDIQTFRPVFVDGERVGIVGTLCHHVDVGGGAAGSYYAAATEIFHEGIRIPPLRLVDKGTLNTGVFEMLLYNVRQPDETRGDLNAQIAALGIGARAVARIAKKYGSANLSAAMSAILDGSERMMRAAIAALPDGTASFVETVDDDGQSDTPIRLEITITKKGDTIALDFAGSSPQVRGPVNNTPAMTCSAVYYALLAALGSDIPANSGCYRPVSVNLPKGSVVNAQFPAPVVGRMVVNHRIATCVFGALAQIAPERIPAAYYAISYVYAVSLVQPNAKRQVYFDIEVGGWGGHAGGDGASALSCGLHNNTNAPIEMVEAKYPVVFTRYGLLPDSGGAGTHRGGLGLVREFRLEAAEGSLSTNFERFRFPPYGIKGGEPGSLSSTTVTHADGTTASLNSKVSGIPLSAGDLVTIKTSGGGGFGDPKGRDRAKLAEDLAEGLVTPEAARTLYGAPELAAAAATVKTCGSKSPARAKTGVAA</sequence>
</entry>
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        <submittedName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2242"/>
    <dbReference type="EnsemblBacteria" id="BAF88240">
        <property type="protein sequence ID" value="BAF88240"/>
        <property type="gene ID" value="AZC_2242"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2242"/>
    <dbReference type="eggNOG" id="COG2982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012870_2_0_5"/>
    <dbReference type="OMA" id="EFWPTPR"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="AsmA_C"/>
    </dbReference>
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        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="2">
        <location>
            <begin position="470"/>
            <end position="651"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="724" mass="75386" checksum="02A06A4BF1602797" modified="2007-12-04" version="1">MPWQGFRTKRCRLVRALPLPVPAGPESGAAEATPFLAPVTALPVDRLEPSLERDTEPADCRATGGTGRHAHGVTPWVRGSDLASSWNVRTDVVKIGLKARRLALAAGISAAAGVGVCLLALAIAPALVPQGEVRRAATEALAASSGRDVRIEGESRFSLVPYPRIVLQRVTLAMPGTSALESEQVVARLRLLPLLLGRADVSSVTLRRPILTMSGAVEVPHLSLAPFVRTPTAPSLRIEDGTIAWRDSGGLTQELVSGISARLDHSSGGKGLSASADFTWRDKTTSGRLTVADASAFLDGMDSDTRLDLFSDGATLKFRGVAAAGANPAAEGDIALDSPDLRSVLNWVGTTPPTSGGFGRFSFGARLSAHGREISLTPAYVEMDGNRGEGGLTLKLDGRRPSVEGTFAADAMNITPYGRKSLTGNGGRDWDHGHLDVSLLHKADLDLRLSANSIRADDSLFERVASSVVLRGGRLLASVGEAQAWGGLLRATLSVAPAEAPAHGTAVRVEMDGNGVALEKALGDIADIRRLEGKGDIQASISGQGDSIYAIAQSLGGAVSVKASAGAIVGLDVAQALRHLEQRPLSGGGDVRGGRTSFTTMEAKAQIVDGKATLDTARITGRQVQLQLAGSVSVADRTLDLKGDASLVNGSGEGTKFELPFIVQGTWDNAFVMPDAQSLIRRSGAAQPLLDAVRSRGGDAAVRSVIEQISKPSPLLPTGAKTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5E1</accession>
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        <submittedName>
            <fullName evidence="7">L-lactate dehydrogenase</fullName>
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    <gene>
        <name evidence="7" type="ordered locus">AZC_2267</name>
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    <organism evidence="7 8">
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170794.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2353"/>
    <dbReference type="EnsemblBacteria" id="BAF88351">
        <property type="protein sequence ID" value="BAF88351"/>
        <property type="gene ID" value="AZC_2353"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2353"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_37_0_5"/>
    <dbReference type="OMA" id="EWEFYLE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="36"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="340" mass="37846" checksum="0E38F05908B7A002" modified="2007-12-04" version="1">MDALRWRARGPSLAPAAVHRSGGQGLAMRSDTVRLPPLNALRVFHAVMRHGSFRSAADELLVSPQAVGQQIKLLEDTLAVPLFDRRGRAIEPTEEAILLSHYVQSGFDEFREGVRRICKVGHRNRINLNASPYFATRYLVDRLDRFRDRLPGADIRLKTMVELPDFSADEVDAAIQWGFGQWRDYESTLLVQDPKVICCSPARASALRSPQDLRTAPLLHLVLATNLWPRVLRHLGVDPGEVQKEIQFHDAASMRRATLSGLGIGLISVLDAQEDLKAGRLVAPFGLDAMAGMDPADVPGFYLVLPRSNRRLKSVAAFCEWILSEDWSRMEPDAPFPAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8I658</accession>
    <name>A8I658_AZOC5</name>
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        <submittedName>
            <fullName evidence="10">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2366"/>
    <dbReference type="EnsemblBacteria" id="BAF88364">
        <property type="protein sequence ID" value="BAF88364"/>
        <property type="gene ID" value="AZC_2366"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2366"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_3_5"/>
    <dbReference type="OMA" id="EHKDGQR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="33"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="219"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="371"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="371"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="477"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="540" mass="58979" checksum="624103079EDB3C61" modified="2007-12-04" version="1">MTSFSELGLAEPIVRALTEEKHVTPTPIQAQAIPAILSGKDLIGIAQTGTGKTAAFGLPILDHLSRNPRRIEPRSCRVLILSPTRELSGQILDNLDKFGRHIRLSTTLAIGGVPMGRQIRALQRGVDVLVATPGRLMDLVENNALKLDTVEVFVLDEADQMLDMGFVHAIKAIVRRLPHKRHSLFFSATMPSAIADLAASMLRNPVTVAVTPVAKTADRVDQRVIFVEKPAKAKMLAEVLSTEEVDRALVFTRTKHGADKVVQVLARAGHKAEAIHGNKSQNQRDRVLAAFREGSLRTLVATDIAARGIDVTGVSHVINYDLPNVPESYVHRIGRTARAGREGIAISFCDGEERAYLRSIEKLIRMTLPTTDRRGEARPAEAADAVGEDRPRANAQPRGERQERREPRGERKEARPPRAERPQGERVQGDRPRGERPRGERTGAERNGAERNGAERHGAERVHSERPAGARQRSAAGPHGEGRKADARPAHGGRAEQPRSERGGRAQGGQRAQSSEIGAIGFMRAPARSDKTGPARRPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6P8</accession>
    <name>A8I6P8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amine oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170962.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2436"/>
    <dbReference type="EnsemblBacteria" id="BAF88434">
        <property type="protein sequence ID" value="BAF88434"/>
        <property type="gene ID" value="AZC_2436"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2436"/>
    <dbReference type="eggNOG" id="COG2907">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028123_1_0_5"/>
    <dbReference type="OMA" id="RAWASWN"/>
    <dbReference type="OrthoDB" id="630753at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="450" mass="49763" checksum="E09EF4BEFC053068" modified="2007-12-04" version="1">MSSLRAPGADRPLRIAVIGSGISGLSAAWLLSSRHEVTLYEADRRIGGHSNTVDTPAGPVDTGFIVYNEAAYPNLTALFAHLNVPTKWSDMSLGVSLDRGRLEYSGDSLRKLFAQPANLVSGRFWTMLRDLLRFYREAPAAVAALEDTPLDVYLAAEGYSAAFRDDHLYPMAAAIWSTPAAEIGAYPAAAFIRFCINHGLLQVLNRPLWRTVDGGSREYVRRLLAPLGDRVRVGCAVRSVRRVSGLVDVTDQSGNRAFFDHVVIATHADQALRLLTDPTLTERQLLGAFRYSTNEAILHRDTSLMPKRKAVWSAWNYMSERDGDGARLSVTYWMNRLQGLPMDQPLFVTLNPPREPRAGTVLRRETYTHPTFNTEAMATQKQLWTIQGQHNTWYCGAHFGAGFHEDGLQAGLAVAEALGGVRRPWTVANESGRIFLQPREAAMPALEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8I758</accession>
    <name>A8I758_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2082</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170609.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2082"/>
    <dbReference type="EnsemblBacteria" id="BAF88080">
        <property type="protein sequence ID" value="BAF88080"/>
        <property type="gene ID" value="AZC_2082"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2082"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_6_1_5"/>
    <dbReference type="OMA" id="LYLCHDY"/>
    <dbReference type="OrthoDB" id="1581636at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="25"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="297" mass="32686" checksum="AF1B508252AFAC61" modified="2007-12-04" version="1">MLPIPHAVDLSVKPEVTAFFDAPTNTVSYVVKDPQSNACAVIDSVMDIDYAAGRIAFQSADAIIAFIQDHGLRLEWLIETHAHADHLSAAPYIQRTLGGQMGIGENITIVQETFGKIFNEGTEFQRDGSQFDRLFKDGDTYRIGSMTAFAMHTPGHTPACMTHVIGNAAFVGDTLFMPDGGTARADFPGGDAHVLYRSIKRVLALPPETRLFMCHDYGPNGRDIRWETTVADERAHNIHVRDGVSEEEFVAMRTARDATLDMPRLIIPSIQVNIRAGELPPPDETGKRFLKVPINGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7T9</accession>
    <name>A8I7T9_AZOC5</name>
    <protein>
        <submittedName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
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    </evidence>
    <sequence length="213" mass="22700" checksum="C555F566ACE8CA42" modified="2007-12-04" version="1">MDIIEHGRWAAYVPQTIHPLAPPNALYWRQEETGEDWYAYSRRVWNILGGVDASGTVKLVLDAAGTVLLANRDASRLMPPVGRVIELAGAGVEEPPLGATLVDGRFIGKAGESPSAPLVVPREISDRQFFQGLALKGLITEEEAISAVSTGALPAAFETLIGQLSAADRFTARMLPSGATSFLRTNPLVDTLGAMLGMSPGAIDELWRFCGGL</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <sequence length="362" mass="37379" checksum="188341E8F95936EA" modified="2007-12-04" version="1">MPSIRVPCVLMRGGTSRGPFFLSSDLPTDVELRDAILLSALGAGHELQVDGIGGGNPLTSKVAIIGPSTRGGAQVDYLFAQVKVSERVVDTSPNCGNMLSAVVPFAIEQGLIAATPGTTTARVHNVNTGKLIDVTVSTPGGRVTYEGDAVIDGVPGSAAPILMTFLDVAGAKTGRLLPTGQAQDEIDGLPVSCVDAGMPLVILRAADLGKTALEAPADLDRDRPFMDRLNAIRIEAGRRMGLGDVSGLVIPKPVILSPFAAETPALAARYFMPHSCHKAFAVTGGIGLAMAAATPGTVAAEAIGAQSPASLSIRHPAGRLDLRIEQSPGDTPRISVLRTARRLFEGAVFARIDQDEGARAAA</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2692"/>
    <dbReference type="EnsemblBacteria" id="BAF88690">
        <property type="protein sequence ID" value="BAF88690"/>
        <property type="gene ID" value="AZC_2692"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2692"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049343_5_0_5"/>
    <dbReference type="OMA" id="YDNPGTT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="336" mass="35114" checksum="5A8240B81A31070F" modified="2007-12-04" version="1">MQESPIGPISDPFSRSSSAPLVPAPSRAPSPVLLMTSPASPFHGLSAFPITPSDTQGRVDTAALEILLTRLVAAGVDSIGLLGSTGTYAYLSRTERRRAVEAASALVAKRIPLVVGIGALRTDEAVDLARDAAEAGADGLLLAPVSYTPLTEDEVFAHFAAVAAATDLSLCIYNNPGTTHFTFTPALIGRLAGLPNVVALKNPAAAPVDAPTLHANLRAAVPEAFAIGYSADWNVTEAILAGGQAWYSVCGGLLPEPTQKLMRAAQAHDIAQVGMWKARFEPLWALFRELTSLRVIYAAADILGLSTALPPRPILPLAPTHHPRIAAALEPLLQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8Q9</accession>
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        <submittedName>
            <fullName evidence="3">Amidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2693</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171217.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2693"/>
    <dbReference type="EnsemblBacteria" id="BAF88691">
        <property type="protein sequence ID" value="BAF88691"/>
        <property type="gene ID" value="AZC_2693"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2693"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_4_5"/>
    <dbReference type="OMA" id="RIPAFNC"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
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    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="463" mass="49296" checksum="8EB6CDCF2889D638" modified="2007-12-04" version="1">MSSPLDLSALELVAAFRARRLSPSEYFDALLPYVAASEPKLGALYAFEPERVRAEAAASTARWAKSAPNGPLDGVPVTLKELIATEGLPVPLGTAATDLVPATADAPPAARMKEAGAILLAKTTVPDYGMLSSGLSSFHTLARNPWNLACNPGGSSAGAAAAGAAGYGPLHVGTDIGGSVRLPAGWCGLVGFKPSLGRIPIDPYYVGRCAGPMTRTVAESALMMQFLAKPDWRDATSLPPEDIDWMDLEGMSVKGLRIGLMLEAGCGMDVEDEVRKAVEAAARRFEAEGAEIVPAPGVLTRAMLDGLDDFWRARSWDDISALPPEKRAKVLPYIVDWAAGGAHVDGPRAVRGFNQTMKMRQACATLFHGLDYLLTPTNNVSAFPAEWASPVNDPAKPFEHICFTVPWNMSEQPAISINCGFTQAGMPIGLQIVGPRFADHAVLRIAHLYEGWRGPITNWPKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9A2</accession>
    <name>A8I9A2_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Pyruvate phosphate dikinase</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2763</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171287.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2763"/>
    <dbReference type="EnsemblBacteria" id="BAF88761">
        <property type="protein sequence ID" value="BAF88761"/>
        <property type="gene ID" value="AZC_2763"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2763"/>
    <dbReference type="eggNOG" id="COG0574">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_015345_2_0_5"/>
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    <dbReference type="OrthoDB" id="997616at2"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
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    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
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    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
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        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="2">
        <location>
            <begin position="61"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="PPDK_N" evidence="2">
        <location>
            <begin position="298"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="1">
        <location>
            <begin position="416"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="531" mass="55799" checksum="5AB63AE7929F6362" modified="2007-12-04" version="1">MRIVRIAPDMTDLPSAEQVGAKAANLARMAALGLPVPPAFVLPVSLCAATVAGEPKARKALEEGLGEGIAFLEERTGRRFGDGRQPLLVSVRSGAARSMPGMLETVLDVGCTRLATQGLIRMTGHPRFAWDCRRRFLESYGSVVLNIDPHGFDRAAAALAAAEGLPDALDLDGEALERLSETYQHFIEEADESVPDAPMEQVLAAAQAVYRSWMSPRAVAYRRIERLEHLAGTAVTVQAMVYGNRGLTSGAGVAFSRNPSTGDAAPMIDVLLSAQGEEVVSGSRTPLGEEVLRAAVPEAAAELRDVLARLERAFGDVQDVEFTVEDGRLFILQTRNAKRTPQAALRIAVALVEEGLITPHEALARLDDLDMDVLSETHLAETGDPAAYGTGASTGVACGRVAFSSETAQRMAGGGEPVILVRPDTSTADVTGFSVASGILTAVGGRTAHAALVARQMGKPSVVGCAALVMDEAGHVARIAGQEIHEGDWLALDGGTGAIYTGRFEIVTSRPEADLAQVAAWRTAAPVPACA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9V5</accession>
    <name>A8I9V5_AZOC5</name>
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        <recommendedName>
            <fullName evidence="4">Chitooligosaccharide deacetylase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2837</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2837"/>
    <dbReference type="EnsemblBacteria" id="BAF88835">
        <property type="protein sequence ID" value="BAF88835"/>
        <property type="gene ID" value="AZC_2837"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2837"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_588819_0_0_5"/>
    <dbReference type="OMA" id="TIGTHSE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0536">Nodulation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="8">
        <location>
            <begin position="153"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="351"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="104"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="464" mass="47866" checksum="D597729646F9ACF5" modified="2007-12-04" version="1">MSPPPAGAEPADAEAPRAVRNGRPRLQKRRRRPAPCGLRHMRSILLAGLVASIASSALAQSVLPAAPSPQLPAAPALPAAAPIAPAVPAAAAASATPASTGAGLTPPPQLPPPSACPGNPDALGVSRVIAIDPKTSPFLGRLQYKQTLPLEKGEVVLTFDDGPLAPMTTRVLDTLAHECVKATFFIVGRMAHSNPHLLQRTLADGHTIGTHSETHPLIFPKLTQEAGVQEIEQGFASVTKALAPVGAAPNPWFRFPGLGRTKFYEAYTQEHGIAVFSVDEVADDWMHLKPEEVEKRALDRLEARGGGILLLHDIQPATAVMLPNLLRELKARGFRIVHVVPATAGMVASLPGPGPRGHIQPAAASATTAAPGTAPAKPAQPKPATAPKPATPATATARPVPPTPRTTATTAAAPAEPAATGAPQAISPHAQAGDGGSDAPGLGQFWPRLWNDTMKGLSGGTDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA71</accession>
    <name>A8IA71_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Bacterial periplasmic substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2472</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170998.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2472"/>
    <dbReference type="EnsemblBacteria" id="BAF88470">
        <property type="protein sequence ID" value="BAF88470"/>
        <property type="gene ID" value="AZC_2472"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2472"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071560_0_0_5"/>
    <dbReference type="OMA" id="CLILTHR"/>
    <dbReference type="OrthoDB" id="785019at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723525" evidence="1">
        <location>
            <begin position="28"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="42"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="326" mass="33892" checksum="C55D4DD011E1AAB0" modified="2007-12-04" version="1">MSFFPSIRSFVAAVTITGVAAVGAAKADEISVTQWGTSLYGAPYAVAMAEGLFKKAGVDITSIIGSGGGGTTVRNLLASDTPYGDVAIAAALAAQRQGLDVIIVNTGTRSVAEASLVTMPDSPIKSLKDLEGKKVAITSPKGVSEMLLLMALKEQGVDASKVERVASGGYVNGLTMLEQGAVAAAALIEPLSIIRADKYRTVVNYGKVLPPMTTSVGITTRAFAKANPAKLKAIIAGRADGVKAIYADPAKAAEIVGKDFKLEPKIAKIAVDNMIGPRMWSEGEFSIPELNRTVDGLKLIGEVTADVDWSKLLDPSYLPPALQGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB51</accession>
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        <submittedName>
            <fullName evidence="4">3-hydroxyacyl-CoA dehydrogenase</fullName>
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    <gene>
        <name evidence="4" type="ordered locus">AZC_2610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88608.1"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2610"/>
    <dbReference type="EnsemblBacteria" id="BAF88608">
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    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
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        <property type="project" value="UniProt"/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Ussery D.W."/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="311" mass="34688" checksum="CCD57A56EB452FB1" modified="2007-12-04" version="1">MIVREKPNLFSIFFIVRRGSGSILPRILPQMLLVMTLSSVVVYGHRHAPDWVPVVSSAPFALIGIALSIFLGFRNNACYDRWWEARRQWGTLVIACRNFGRQTLLLEERGGSEGAHLRIEMVRLVIAFTYALVQHLRPSKSQPSVPSGLATSMSERFLTSRNPPDYLLRQITSLLVGARTRGLLSDIEFSLIEGTVGQMETVLGSCERIRSTPVPFAYTLLLHRTAYAFCFLLPFGFADLIGWLEPIAAGMVAYTFFGLDMLGDELEEPFGELPNDLPIAALAETIAINLREALGETDLPPFPEPVNYVLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC68</accession>
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            <fullName evidence="7">Sulfate ester transporter permease component</fullName>
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        <name evidence="7" type="ordered locus">AZC_3168</name>
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    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171692.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3168"/>
    <dbReference type="EnsemblBacteria" id="BAF89166">
        <property type="protein sequence ID" value="BAF89166"/>
        <property type="gene ID" value="AZC_3168"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3168"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_046113_1_2_5"/>
    <dbReference type="OMA" id="PPLAYYT"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="80"/>
            <end position="104"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="132"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="72"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="265" mass="28503" checksum="CF6E1500A29F86BE" modified="2007-12-04" version="1">MTAPLVETVPVASAPWLSPRLRRGLVLPLLLLITWEASSHLRLVDPRFLPPLEAIAITGWEEIWSGDLFLHLGASLARNLTGFAIGSVLGIAFGLLLGLSPLAARIAGPSFHAAKQIAVLAWIPIISVWFGFAETAKVVFVAVAAFVPVALNTIEGVASAPKALVEVSDVLTFSRRQRIRRVYLPSALPSILTGIHLGLIYAWLATVAAEYFMTVGPGIGGLIIAGRERFQMELVMLGVVILGAVGFLLNHIATLIEARLLRWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICK4</accession>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; alginate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3221"/>
    <dbReference type="EnsemblBacteria" id="BAF89219">
        <property type="protein sequence ID" value="BAF89219"/>
        <property type="gene ID" value="AZC_3221"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4880" evidence="3">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="112"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="333" mass="36088" checksum="5B93C3D2E303E61A" modified="2007-12-04" version="1">MTRPDYPSATRAELDAPMAPLAEKALEWLVFLHSGQETDADWAAYEDWRASGVAERKAAEQAERLWAGIGPALRRPRAGLPRRSVLAGAGIALVGGAGLAAFLGMRRDLFADVRTAVGERRTLTLADGTRIELDAATSLDLHYSAKTRRIELLEGRIFVSVAADPNRPFIVDAGGGAARALGTAFEISRSGDMVNVVVSEHTVRVCYPRETDGPHVDVDAGSEVEFSRAGGLARPHAADVVSRMSWRNGLLAFQDRPLAEVVAQISRYRHGRIVIVDGELARLPVSGLFESADTAALLDALSAALPVTIDQLPWLTLIRRDASRPLEPFTRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDC1</accession>
    <name>A8IDC1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-type dipeptide transport periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2913</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171437.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2913"/>
    <dbReference type="EnsemblBacteria" id="BAF88911">
        <property type="protein sequence ID" value="BAF88911"/>
        <property type="gene ID" value="AZC_2913"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2913"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_4_5"/>
    <dbReference type="OMA" id="WRLWELS"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724349" evidence="5">
        <location>
            <begin position="27"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="6">
        <location>
            <begin position="70"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="530" mass="57350" checksum="4E3B25B35B24484B" modified="2007-12-04" version="1">MTLASTFRTLSLAALLATTASGALFAQTLTIGVRSGPASMDPHFTSTGVQAEAAKHVFDTLVKSGDNLQLEPGLAESWTAVDDTTWEFKLRKGVKFHDGSDFTAEDVKFSIERIPNVTGPNPTTVYVRRVKTVEIVDPLTIRIKTDGPAPTLPNDFVRLFVVSHTAAKDFSTKDTAGDGFNSGKATIGTGPYKFVSWTPKEELVLTRFDGYWGGKEPWEKVVRKEIPNDAARVAQLKAGQLDLISRVPPADVPTLEKDAKLKVDKADSVYVFLVEFDFRDKPALVTAKDGSPLPKNPFLDPKVREAFDLAIDREALAEIAMEGLGKPASQLVTDTIFGFNKALKVTKADPKKAKQLLAEAGYPNGFKVALTFTTDRLQSDGAVGTSIVQMLAAAGIDAQANGQPSTVFFPARTRGDYGLSMWGWGTLTGEANYTLAGLMHTNTPETKLGGFNVRGYSNPALDKLIEQAAVEMDVPKRRTQLEEAAALVAKDRPTLPIASIVSAWAMQKAKVTFTPRVDEDTLAMNVKPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDM6</accession>
    <name>A8IDM6_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized conserved protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2964</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171488.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2964"/>
    <dbReference type="EnsemblBacteria" id="BAF88962">
        <property type="protein sequence ID" value="BAF88962"/>
        <property type="gene ID" value="AZC_2964"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2964"/>
    <dbReference type="eggNOG" id="COG5403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_844533_0_0_5"/>
    <dbReference type="OMA" id="PLFDMMM"/>
    <dbReference type="OrthoDB" id="1856426at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009282">
        <property type="entry name" value="DUF937"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06078">
        <property type="entry name" value="DUF937"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="236"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="310" mass="32406" checksum="360E3553E405D441" modified="2007-12-04" version="1">MDQFTQLLKSAQGGHGVENLANLYGLSAQQTQRVMEALIPAFSVALQRAMQSPESLANLTILMMSGPYGGLYEHPPQKPVELAKPGDPVLEAVFGSPDVAKAVADHAASSSGLAAAVVKQVMPSFATLLLGGLAKSLAASGAMSQMLAASLARASGQQLPTGNPWVDALNNFISPPQAQQAPQSTGNPWVDAFAQMMVQSPFGLRGANARSNNPWQALAETISASMAAFQIPAQGWTAAPPPKAAPTPPPPPPEPANPALPFQDFFAKLFTQGCPPAFNAFDPSRSSGPTGFYPFDVWAQMLDRSSGRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF88</accession>
    <name>A8IF88_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5664 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3591</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3591"/>
    <dbReference type="EnsemblBacteria" id="BAF89589">
        <property type="protein sequence ID" value="BAF89589"/>
        <property type="gene ID" value="AZC_3591"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3591"/>
    <dbReference type="eggNOG" id="ENOG5033MRT">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1988059_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044038">
        <property type="entry name" value="dATP/dGTP_diPOhydrolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18909">
        <property type="entry name" value="DUF5664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5664" evidence="1">
        <location>
            <begin position="16"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="125" mass="13762" checksum="B4E7147394ED3EC7" modified="2007-12-04" version="1">MTAPAYPDDNPKTLVGLKKPPIQFIPPSAIVFLGQAMADGAKKYGPMNWREKRVSTSVYYDAGMRHRMSFWDGEDVAPDSLVHHLAHSMACDAIVLDALVTGNLNDDRPIKGSLPDLIVQLTKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFY2</accession>
    <name>A8IFY2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative pyruvate, phosphate dikinase regulatory protein</fullName>
            <shortName evidence="5">PPDK regulatory protein</shortName>
            <ecNumber evidence="5">2.7.11.32</ecNumber>
            <ecNumber evidence="5">2.7.4.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0001</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ADP + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] = AMP + H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase]</text>
            <dbReference type="Rhea" id="RHEA:43692"/>
            <dbReference type="Rhea" id="RHEA-COMP:10650"/>
            <dbReference type="Rhea" id="RHEA-COMP:10651"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:83586"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + phosphate = diphosphate + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase]</text>
            <dbReference type="Rhea" id="RHEA:43696"/>
            <dbReference type="Rhea" id="RHEA-COMP:10650"/>
            <dbReference type="Rhea" id="RHEA-COMP:10651"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:83586"/>
            <dbReference type="EC" id="2.7.4.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.32" evidence="5"/>
    <dbReference type="EC" id="2.7.4.27" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF85999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0001"/>
    <dbReference type="EnsemblBacteria" id="BAF85999">
        <property type="protein sequence ID" value="BAF85999"/>
        <property type="gene ID" value="AZC_0001"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    <keyword evidence="1 5" id="KW-0723">Serine/threonine-protein kinase</keyword>
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    <feature type="binding site" evidence="5">
        <location>
            <begin position="178"/>
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        <ligand>
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        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
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    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00921"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF85999.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="305" mass="33788" checksum="D0852B8F5D2C0772" modified="2007-12-04" version="1">MCCACMGPEGMPSCTRRPQTGGETVSSPHQNYFHLHLVSDSTGETLINVGRAACAQYVNVSPIEHVYPLVRSTKQLDRVLAEIEASPGIVLYTLVDKEIRERLKERCRELSVPYMSVLAPVVQLFQSYLGGEPQPRVGGQHALDATYFKRIDALNYTVSHDDGHLTDDLEEADVVLLGVSRTSKTPTSIYLANRGIKTANIPLVPNVPIPPNLSRLKKPLIVGLIASPERIVEIRQNRLLGLNADTTNSSYVDRDAVSEEIANSRRLFARNGWPLIDVTRRSIEETAAAIIGHLSERRRRSIVET</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86039.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF86039">
        <property type="protein sequence ID" value="BAF86039"/>
        <property type="gene ID" value="AZC_0041"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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        </source>
    </evidence>
    <sequence length="416" mass="45921" checksum="C878B2DF178370D3" modified="2007-12-04" version="1">MSQPVQTSNSEDRAVAEPAVPRIAPQRHIELVPIAPEALPQHVGAEGRPHVAVQPWWRRHGLFLGLFVLPVFAALLYFGLIASDIYTSEAKFLVRASARSVAGSLSAMMPGDSMSRAADETYAVSEYMLSRDAAAELAKTAGLRDVMDRSEADMFNRYPSWFGKENEEQFYRAYRRMVDVVPDGGTGISTLVVRAYRADDAQAVAKALIAAGEKFVNKLNLRSNEDAVKFSESMVKETQLRLSDVEARLAAYRNSQLVVDPEKESTQSLAILGKMTTEISRLEATLSQQMAMAPDSPAITPLRERIAAYRTEMQKQQKNVVGGADSIASKLQGYELLILERDLAGRALAVATASLESARQEAQSQRIYLQEVTEPNLPDQALQPKRLLAIFVVAFLSLCVYWIARSFIANTLDHQA</sequence>
</entry>
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    <accession>A8IG71</accession>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="1 2" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <sequence length="293" mass="31843" checksum="E94ED726C4B0E6F7" modified="2007-12-04" version="1">MSVIPFPRRSTAPDVRSGAIPGLDPEVMVGMPHLGFGGLSETWLLKECGHRHWLALAQAAGQRVPDFRDATGAPVYAAFCGVSLANARLDRVAENDTLIFASTLARISATQFVSRHSVRAPDGVVAELELVSVFVKRQVEGRNRSVARVRPEGLPPLDPGEVSRTSALAAALRGGEWDTHMGFARTQAHECARVMLTPCPSQDFNGAHFLYFAAFQAFADRAEWELLAPPAGTLTLARDLVYHGNIEPGERLAACLLGVRETPGELAHWLRLAREDGTPLADIFTRRALPPIR</sequence>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    <sequence length="357" mass="38644" checksum="81C8C4DEDA7BA0DF" modified="2007-12-04" version="1">MTAAGVPEKETYKRGYARERDSRCCRKWMMPRLFPLLAFLTVTAAAPAALAQGVLLPPGEVPNASGGVSGADLFSPQPIAPQMTPRQLTPPQPTAPQQIPPSAAPRPATAQPAPSAAPPAPAAQAAPATPPASAPLPQQRPASANQPRPPAAAQAPAAAPTSPRVAPPAQAQQALPQAGQQGQIERASPATIEKLTTYWNSVQTLVGTFVQVDADGTRKTGDFYMQKPGRVRFEYNPPTQIQLISNGQNVAVRDRRLNTQDLTPLNQTPLRFILAERIDLTRNSNVLGVYQDNLYIQVIMQESVPMMGTYRLQILFDAKDFQLRQWTVTDPQGYDTSVAIYDLNYTQRPDPSLFVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGM1</accession>
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    </protein>
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        <name evidence="7" type="ordered locus">AZC_0107</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168638.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0107"/>
    <dbReference type="EnsemblBacteria" id="BAF86105">
        <property type="protein sequence ID" value="BAF86105"/>
        <property type="gene ID" value="AZC_0107"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0107"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_5_1_5"/>
    <dbReference type="OMA" id="NQTAIPH"/>
    <dbReference type="OrthoDB" id="1345431at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
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    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="103"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="235"/>
            <end position="255"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="386"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="421" mass="44928" checksum="1BC145FFBEBEA741" modified="2007-12-04" version="1">MAPTRYRWFVIFLLFAITVVNYIDRAAIAYAITAMERDLGLSPAAAGSILGAFGVGYAITTLLGGFAVDRYGARLVLTISAVLWSLSIGGTAMATGFASLYAARVLLGVSEGPNFPALTGAVSRWLAPNERATALGNALVAVPVALAIGGPIVTQLLAHLDWRTAFGVLFALSIMWVPLWLVFFRNRPEDSRFVNAAELAHIRTPDATGPAKPAAGHGPGLARLLLTNPTLVSNYWAFFVFGYFLFFFMTWLPSYLEQAYHLNLKQVGLFTVLPWLAAAVALWSMGRWSDHLLRTTGRLRVARSYLIAGSQLVAALAIVPVALTDNLAVAITGITVAVAASMGSNAAYYAVNVDVVPERAASALGIMDFAFALAGFLAPAITGWVLALRGSFTDGFALMAALALSSVVVVLLFHHPDRHRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGN9</accession>
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            <fullName evidence="2">NADH flavin oxidoreductase</fullName>
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        <name evidence="2" type="ordered locus">AZC_0114</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168645.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0114"/>
    <dbReference type="EnsemblBacteria" id="BAF86112">
        <property type="protein sequence ID" value="BAF86112"/>
        <property type="gene ID" value="AZC_0114"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0114"/>
    <dbReference type="eggNOG" id="COG1902">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012153_2_0_5"/>
    <dbReference type="OMA" id="NQRRDQY"/>
    <dbReference type="OrthoDB" id="1033671at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="PTHR43303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="367" mass="38639" checksum="EF61C32FB4CE50A2" modified="2007-12-04" version="1">MPLLFEPLTLRGLALDNRIVIAPMCQYSAKEGAATDWHLIHLGTLAMSGAGLLIIEATGVTPEGRISPFDLGLYSDETEAALAGVIARVKAQIPAEGMPRFAIQLGHAGRKASSAQPWKGGGQVPEAEGGWQTVAPSALPFRNADAPPAALDDAGLDRLRTAFAEAARRAARIGFEAVEIHAAHGYLLHQFLSPLSNARTDAYGGSLENRMRFPLEVFEAVRAALPDSVPVIVRVSGTDWVDGGWDIEGTIAFAQALKARGADAIHVSSGGLSPLQQIPVEPGYQVPLAKAVKEATGLPTIAVGLITEPKQAEAVLAAGEADAIGIARGALYDPRWGWHAAAELGASVTAPPQYLRCQPSGLRHLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGT8</accession>
    <name>A8IGT8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_0133</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168664.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0133"/>
    <dbReference type="EnsemblBacteria" id="BAF86131">
        <property type="protein sequence ID" value="BAF86131"/>
        <property type="gene ID" value="AZC_0133"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0133"/>
    <dbReference type="eggNOG" id="COG4174">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_1_5"/>
    <dbReference type="OMA" id="TFVVIQF"/>
    <dbReference type="OrthoDB" id="1479518at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="137"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="370" mass="40621" checksum="B43DF6FB8C32195D" modified="2007-12-04" version="1">MLAYIVRRLALMVPTILGIMLVSFVVVQFAPGGPVERVIAQLTGDDVSATARVSGGGGDFAGGAQAPGAGGGGADASKYRGAQGLDPNFIKELEKQFGFDKPPAERFALMIWNYVRFDFGRSYFRDISVLDLIAEKLPVSISLGLWMTLLTYAISIPLGISKAMRDGSRFDVWTSAVIIVGYAIPSFLFAILLIILFAGGSFLDWFPLRGLTSDNWAQMSWPQRIGDYAWHLVLPLTSMVLGAFATMTLLTKNSFLEEIRKQYVITARMKGLPERAVLYRHVFRNAMLIVIAGFPSAFISAFFTGSLLIETIFSLDGLGLLGFESVLNRDYPVVFATLYIFSLAGLLIGLVSDLTYMLVDPRIDFETRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH46</accession>
    <name>A8IH46_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0172</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
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    <dbReference type="HOGENOM" id="CLU_018816_1_2_5"/>
    <dbReference type="OMA" id="NVYLGQY"/>
    <dbReference type="OrthoDB" id="1432684at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CusB_dom_1" evidence="2">
        <location>
            <begin position="11"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="55"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="373" mass="39730" checksum="36631EDCBC1D4D17" modified="2007-12-04" version="1">MKKRMIMMLIAVGLVFGALYGFQMFKATMIKQALASLRDPPQTVATMEAALSPWQTSIKAVGSVRAEAGADLALESSGTVSELNFKSGDEVQEGQVLLKLRDDEERANLEALKATADVSAIILNRDKEQLKIHAVSQATVDSDTANLKKALAQVTEQQAVVDKKTLKAPFSGRLGIRAVDLGQYVSAGTTIVTLQSLNPIFVDFYLPQQALADIKTGQAVKATVDTYPGQSFEGTITAVSPKVDTSSRNVQVRAEFKNDDKRLFPGMFATVEVSVGKPSDLVTVPQTAITANPYGDIAFVVEKKEGSSTGLSVKQVFVKTGETRGDQIAVTSGLAAGDQIVVAGQMKLHNGSQVTVNNAVLPTNTPSPSITDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHL2</accession>
    <name>A8IHL2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_3292</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3292"/>
    <dbReference type="EnsemblBacteria" id="BAF89290">
        <property type="protein sequence ID" value="BAF89290"/>
        <property type="gene ID" value="AZC_3292"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3292"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021900_0_0_5"/>
    <dbReference type="OMA" id="HYMIVKR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="362"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="589" mass="63137" checksum="C131D669500B862D" modified="2007-12-04" version="1">MIQQVKHDGERIYERSRASRKGQACCFIALPSAELLVFRGTGSDGRHKERRRQVVKRRGASLGLLMLLAVWLGLNALFLGLNARKALERAREEVSSSGLALHRVVSQRVAQHDALLTSLVALALVADPPPQDAILQVSQRFMRFYPRVAGIDLVALTETAGTVALHPVISIASPPADHRSLAAALYALTPGEPRSFLDPPMPTHYLVGKKASAANPALAVIIEIDAALLVEPSERPAWAHATLALDGQTLVQWPAEQEAAALSFLPTPRFTRAIDSTSQPLTLTLVRPLSLAEILDPKLSLGFAILSLLALLVLHYAWRQRLAARQSAETARLAEQRTRLLEHETRLAHAARVNALGELASGIAHELTQPLTALLSQSQAARRLARPGSDPALLEQALEANVREARRAGEMLKRMRDYISNRETSPVLTPVARIVDDVAGLVKADLDRRGIALVLENAAPDACILADPIEMEQVLHNLIRNAADSLDGTGLEKSITVRISALPASAATVEGHVEIRVSDSGPGIPETALPRLFEPFFTTKPDGLGLGLSLCATLLERCGGNISAANAPAGGAVFTLTLPEAGAARQAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHL5</accession>
    <name>A8IHL5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">luxR</name>
        <name evidence="5" type="ordered locus">AZC_3293</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <begin position="5"/>
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        <location>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">H(+)-stimulated, divalent metal cation uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NRAMP family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171818.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NRAMP_fam"/>
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        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
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        <location>
            <begin position="69"/>
            <end position="96"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="4">
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    <feature type="transmembrane region" description="Helical" evidence="4">
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        <location>
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            <dbReference type="ARBA" id="ARBA00022692"/>
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        </source>
    </evidence>
    <sequence length="446" mass="47407" checksum="178E2D07FA52D6FF" modified="2007-12-04" version="1">MLDQATKGMNGWRRERGEAALSDVHGTIAVSHRSRLGRLFAFIGPGYLVATGYMDPGNWATSLAGGSRFGYALLFVALLSNMIAILLQALCSRLGVATGRDLAQACRDSFPKPVAFVLWLLAELAICATDLAEVIGTAIGLNLLFGIPLELGVIVTALDVFLILWLQKLGFRFVEAFIVALLGIIGACFFIQIAMADPDWGAVIRGFAPTTEIVTNPDMLYLALGILGATVMPHNLYLHSAIVQTRKHAPTPDGVREAIRFATWDSTFALMFALTINASILILAAAAFHGTGTGEVADLGKAHELLNPLLGSALAPTLFAVALLCCGLNSTVTATIAGQAVMEGFIEMKIQPWLRRLITRAIAIVPAAAVTIAYGEKGASTLLILSQVVLSLQLPFAIVPLVLFTADRRKMGEHVAPRWQTVLAAAASLLIIALNVKLLVDTALGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHV6</accession>
    <name>A8IHV6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Membrane fusion protein (MFP) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">expD2</name>
        <name evidence="10" type="ordered locus">AZC_3327</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3327"/>
    <dbReference type="EnsemblBacteria" id="BAF89325">
        <property type="protein sequence ID" value="BAF89325"/>
        <property type="gene ID" value="AZC_3327"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3327"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023976_1_1_5"/>
    <dbReference type="OMA" id="TYIAADQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010129">
        <property type="entry name" value="T1SS_HlyD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01843">
        <property type="entry name" value="type_I_hlyD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="193"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="472" mass="51793" checksum="A87AEAFF4FC77AAE" modified="2007-12-04" version="1">MQRTPARLADAPQRGVAARRAEVLPPDRHRKVETWYQVLEREAVEAPSGLRGPVIAGTLAVLIGFGGFTTWALLANLDSAAVATGTLVVDSKRKTVSHLEGGILKRLLVQEGDVVKLGQPVALMDDTRARSDLEQYRGRRVGFLAKLARLRAEQSGATQVDFPPPVLDPANPVAVDVLSAERRLFQRRHDAYVGKTQIQRKEIEQRIAEAQSLSALIESAERQRDYISERLTGLKELAGKGFVAKAQLLEQEARVSELKGRVGDYRAQIAKSEQAKASAEATLASIDLDWQSDVATQLQDAQLQLAEVENQITSAKDVLDRLTVRAPQDGVIANIQFRTPGSAIPAGQPIMDVVPEKEQLVVEAKLGTREIVNVHVGGKAQVRLTAYDHRVIPPVDGKIIYVAADQTIDPNSQNAYYVIRASIDAAELEKHPTVSLYPGMPAELMAVRKPRRAIDYLIGPVTESFNRAFREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK65</accession>
    <name>A8IK65_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trbG</name>
        <name evidence="5" type="ordered locus">AZC_3866</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrbG/VirB9 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172386.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3866"/>
    <dbReference type="EnsemblBacteria" id="BAF89864">
        <property type="protein sequence ID" value="BAF89864"/>
        <property type="gene ID" value="AZC_3866"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3866"/>
    <dbReference type="eggNOG" id="COG3504">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058585_1_0_5"/>
    <dbReference type="OMA" id="TDRRIYM"/>
    <dbReference type="OrthoDB" id="1251301at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06911">
        <property type="entry name" value="VirB9_CagX_TrbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2500">
        <property type="match status" value="1"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <location>
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            <end position="147"/>
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    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <sequence length="228" mass="24835" checksum="AD3AE3B34A1E93EF" modified="2007-12-04" version="1">MLSLYRKIHHKEQRHMFGCRHHGREERFAAGGRGEFGGGFGGGWGRGRRGGGGFGGGGGGDFFRIGRMLAQGDLKLLALSLIAEQPRHGYEIIKLIEEKTGGWYSPSPGVVYPTLTFLEEAGYVTAEPDGAKKRFTITEEGRAYLEENKDVADALVGRLSEIGLKVGKMRRWMGKGEEGGEPSGLPRLVDAAIENLKDVAKAKLAENPRTETRIVEILAGVANDLREV</sequence>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="16"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH" evidence="3">
        <location>
            <begin position="420"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="633" mass="68168" checksum="2C7B34B6CC725A4A" modified="2007-12-04" version="1">MGAHSFMHQGLEYRPHIDGMRAIAVGGVVLFHFGLTPLSGGFTGVDVFFVISGFLISKTLYRDVAGGDFSFADFYARRARRIVPAYVAVSLLSTLAAGLLLYPHALRDFAASLLASTVFASNIYFYFSANYFAPAAHELPLLHYWSLGVEEQFYLLFPPLLFAARRCTRRRVPLLLAVVAVASLLSGEMLLRFNPEAAFYLLPFRAFELLIGCLLALPGVRFPAQPRIANGAVLLGLALILGGMVALSERGPFPGTDALLPCAGAALVIWGADRVRTGAGARLLSLAPLRFVGRISYSLYLVHWPVASFGRQLFPFAEGWEFFLGGVATSLLFAVAIYALVEAPCRRWLGTVPRALVASTAGLAVLAALAGTILALGGFPQRVEARVLRMLTYVHYRPNEAFRTGTCFLGPRETAESLRADLCLPARRPLAVLWGDSHAAHYYAGLEPPFAARGYALGQLTASGCPPLPGIVIPARPNCAGFNDFALAEILRLKPQLVVMAGFWSVDPAWLEALEQALSRLEAAGIPAVVLGPGPVFRRSVPLILADRQRAGDRGVTSGDELSAGVVEEIDAAVQAVVTRVPGARYVPVLETICPQRQCPLAADHVPLFFDNAHLTAHGAQVFSRALIARILP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILE7</accession>
    <name>APAG_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">Protein ApaG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">apaG</name>
        <name type="ordered locus">AZC_4024</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172544.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ILE7"/>
    <dbReference type="SMR" id="A8ILE7"/>
    <dbReference type="STRING" id="438753.AZC_4024"/>
    <dbReference type="EnsemblBacteria" id="BAF90022">
        <property type="protein sequence ID" value="BAF90022"/>
        <property type="gene ID" value="AZC_4024"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4024"/>
    <dbReference type="eggNOG" id="COG2967">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128074_1_0_5"/>
    <dbReference type="OMA" id="YVSGCNL"/>
    <dbReference type="OrthoDB" id="1835593at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00791">
        <property type="entry name" value="ApaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007474">
        <property type="entry name" value="ApaG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036767">
        <property type="entry name" value="ApaG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023065">
        <property type="entry name" value="Uncharacterised_ApaG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04379">
        <property type="entry name" value="DUF525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110069">
        <property type="entry name" value="SSF110069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51087">
        <property type="entry name" value="APAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000083604" description="Protein ApaG">
        <location>
            <begin position="1"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="ApaG" evidence="1">
        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00791"/>
        </source>
    </evidence>
    <sequence length="130" mass="14358" checksum="61CF2AFC919EB9AC" modified="2007-12-04" version="1">MYRATTRKIQVTATPRYVAERSEPDQGRHFWAYTIEVVNLGKVSVQLKSRHWVITDAHGHVEEVHGAGVVGEEPVLPPGGRFEYTSGVPLSTPTGIMSGHYDMLAETGETFSVEVPAFSLDVPHMARILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILH5</accession>
    <name>A8ILH5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phosphate transport system permease protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_4034</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172554.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4034"/>
    <dbReference type="EnsemblBacteria" id="BAF90032">
        <property type="protein sequence ID" value="BAF90032"/>
        <property type="gene ID" value="AZC_4034"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4034"/>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="VKHALQG"/>
    <dbReference type="OrthoDB" id="1416748at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="28"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="60"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="274" mass="30428" checksum="D1CD3283D7B83A7A" modified="2007-12-04" version="1">MTSAVDPNLSMSTSVSAKPGAPDAPTKIQVNKLNFYYGQNHALKNINFTIPEKRVTAMIGPSGCGKSTLLRVFNRMYDLYPGQRAEGEVMFDGVNVVGKDLDSTVVRSRIGMVFQKPTPFPMSIYDNIAFGVRLHESLSKSQMDERVESCLRKAAIWEETKDRLHTSALGMSGGQQQRLCIARTIAVKPEVILLDEPTSALDPISTSKIEDLIDELKQEFTIVIVTHNMQQAARCADRTAFFYLGELVEVGPSDVIFTNPKEIKTRDYITGRFG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="component" value="Chromosome"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="22"/>
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    <feature type="chain" id="PRO_5002723689" evidence="1">
        <location>
            <begin position="23"/>
            <end position="207"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90037.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="207" mass="21200" checksum="8879408653A98939" modified="2007-12-04" version="1">MSIRTGLLAVTTLAAGLGAAAADPLPYPSADFALKAVLRDGGSLDLAYADGRMRLELLPKSSPTLIVGIADLKSGKVALMVPSMPKMAMQTDLPPSFSFAALTGSGTKTGTDTVAGEACDLWKIDPVPSQTTAGPTTACITADGIALRTHVEIQGKPQLVYEATALTRGPQDPRQFMVPHGVQTVKLPKSAVAAVPGLNLLAAPSAP</sequence>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    <sequence length="209" mass="22740" checksum="9F85D3C5D203915E" modified="2007-12-04" version="1">MPAPAFAGLTSSPDVSMIRKLYDWVLAYSARPSAPWALAIVAFAESSIFPVPPDVLQVPMSLARPDKAWRYALIATIASVLGGLVGYAIGALLYDSLGLWLINLYGYGQKVDAFRAAYAHYGHWVILLKGLTPIPYKLVTITSGFADYSLFWFVVLSVITRGARFFLLAALLHYFGPAARDFIERRLGLVTLGLLAIVVLGLVAAAYLV</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168999.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0468"/>
    <dbReference type="EnsemblBacteria" id="BAF86466">
        <property type="protein sequence ID" value="BAF86466"/>
        <property type="gene ID" value="AZC_0468"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0468"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_3_3_5"/>
    <dbReference type="OMA" id="PGPYGCL"/>
    <dbReference type="OrthoDB" id="391134at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008949">
        <property type="term" value="F:oxalyl-CoA decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033611">
        <property type="term" value="P:oxalate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045025">
        <property type="entry name" value="HACL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017660">
        <property type="entry name" value="Oxalyl-CoA_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710">
        <property type="entry name" value="PTHR43710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03254">
        <property type="entry name" value="oxalate_oxc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="6">
        <location>
            <begin position="21"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="4">
        <location>
            <begin position="212"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="5">
        <location>
            <begin position="409"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="579" mass="61057" checksum="B3482AC9E26E45F2" modified="2007-12-04" version="1">MSAVAQRVETEADAQQELTDGFHLVIDALKLNGIETIYGVPGIPITDLGRMAQAEGIRVVSFRHEQNAGNAAAIAGFLTKKPGVCLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAKPLCKAAFRVLHAADIGIGVARAIRAAVSGRPGGVYLDLPAKLFSQVMDAAAGEKSLVKVIDPAPAQIPGPAAVDRAINLLKGAKRPLIILGKGAAYAQADEEIRAFVEKSGIPFLPMSMAKGLLPDTHPQSAGAARSTALKDSDVVILLGARLNWLLSHGKGKTWGEPGSKQFIQVDIEPKEMDSNVEIAAPLVGDIGSVVSALLDRIDGSWQAPPADWIESIRSKKEANIAKMAPKLLKNSSPMDFHGALGSLKKVIAERPDAILVNEGANTLDLARGIIDMYQPRKRLDVGTWGVMGIGMGFAIAAAVETGKPVLAVEGDSAFGFSGMEVETICRYDLPVTIVIFNNNGIYRGTDTDPTGRDPGTTVFVKDSRYDKMMEAFGGVGVNVTTPDELYRAVSAAMDSGKPTLINAVIDPAAGSESGNIGSLNPQSVVVRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM21</accession>
    <name>A8IM21_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Formyl-CoA:oxalate CoA-transferase</fullName>
            <shortName evidence="2">FCOCT</shortName>
            <ecNumber evidence="2">2.8.3.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Formyl-coenzyme A transferase</fullName>
            <shortName evidence="2">Formyl-CoA transferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">frc</name>
        <name evidence="3" type="ordered locus">AZC_0469</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>formyl-CoA + oxalate = formate + oxalyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:16545"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
            <dbReference type="ChEBI" id="CHEBI:57376"/>
            <dbReference type="ChEBI" id="CHEBI:57388"/>
            <dbReference type="EC" id="2.8.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate degradation; oxalate degradation; CO(2) and formate from oxalate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CoA-transferase III family. Frc subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.8.3.16" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169000.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0469"/>
    <dbReference type="EnsemblBacteria" id="BAF86467">
        <property type="protein sequence ID" value="BAF86467"/>
        <property type="gene ID" value="AZC_0469"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0469"/>
    <dbReference type="eggNOG" id="COG1804">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033975_2_1_5"/>
    <dbReference type="OMA" id="FFWSPIN"/>
    <dbReference type="OrthoDB" id="969868at2"/>
    <dbReference type="UniPathway" id="UPA00540">
        <property type="reaction ID" value="UER00598"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="CoA-Trfase_fam_III"/>
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    <dbReference type="InterPro" id="IPR017659">
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        <property type="entry name" value="oxalate_frc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="17"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="72"/>
            <end position="75"/>
        </location>
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    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
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            <begin position="136"/>
            <end position="139"/>
        </location>
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    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="247"/>
            <end position="249"/>
        </location>
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        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>CoA</name>
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    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>CoA</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="426" mass="46519" checksum="5C65E14EB1816366" modified="2007-12-04" version="1">MGKALDGVRILDFTHVQSGPTCTQLLAWFGADVIKVERPGEGDVTRTQLRDVPNADSLYFTMLNSNKRSITLDTKNAEGKKVLEDLVKVCDVLVENFAPGALDRMGFTWERLQEINPRIILASVKGFGPGPFEDCKVYENVAQCTGGAASTTGFRDGLPMVTGAQIGDSGTGLHLALGIVTALYQREHTGRGQKVLAAMQDSVLNLCRVKVRDQQRLSRGPLREYSQFGEGVPFGDAVPRAGNDSGGGQPGRILKCKGWEHDPNAYLYFITQAPVWEKICDVIGEPTWKTDPNYATAAARLPHLNEIFTRIEAWTMAHTKFEAMEILNQYDIPCGPILSMKEIIEDDSLYATGTLVEVEHPVRGAYVTVGNPIKLSDNDVPVERSPLLGEHTEEILATVLGFDADRIAEVKHSGAVGLSPVRQAAE</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169008.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0477"/>
    <dbReference type="EnsemblBacteria" id="BAF86475">
        <property type="protein sequence ID" value="BAF86475"/>
        <property type="gene ID" value="AZC_0477"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0477"/>
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    <dbReference type="OMA" id="YGFRNTT"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Leu-bd"/>
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        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
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        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723699" evidence="3">
        <location>
            <begin position="24"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="4">
        <location>
            <begin position="29"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="391" mass="41483" checksum="0E447F9F33BB86CC" modified="2007-12-04" version="1">MKKSLVFGATLLAAVSAAAMARAADDELVLGYMMAKSGPYVSLANTNEIAVDLAVEEINAKGGINGKKIKVVKFDTAGDPKQATTALRRFAEDDSALAVIGPFSSSEVRTTFPVGERSGIAQMSMASSAPGLTKGFSYGFRNTTDEGIVLDQVMTSIKDKKLPAASGAAAYATDDVVSKSIGTLVVPKLFEKYSVPMKGSVDFQLAAFDLSPQVSKLKEMAPDIVGLGSPPEGAVNLAKELKRQGVSTRVIGGTTIADPELPKRMDGAGENLTIGTTFFPEVNDKTKAFAAEFGKRTKAAGLPRTEPNQMDAAVYDIVYLYAEAMKRAAVTGDKAKLVAERTGVRDALAKMKDFEALEGKISFRDGDAVKPVYILEVKGGKWTLLDTRMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM56</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0492</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
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                <person name="Lee KB."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0580"/>
    <dbReference type="EnsemblBacteria" id="BAF86578">
        <property type="protein sequence ID" value="BAF86578"/>
        <property type="gene ID" value="AZC_0580"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0580"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_3_5"/>
    <dbReference type="OMA" id="YASNREP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="339" mass="36427" checksum="B1ECDF3CFBB05D6F" modified="2007-12-04" version="1">MPPASAWGAVGRSPCTECPMSRSKADARAASRAPEIPLRMSALHLDVFNAVVVTGGVTAASRQLHLSQPAVSRRLADLERVLGFDLFLRDGKRLIITPEGKAFHEELSISYLGLEHLTKVALDIRELRRGHLRFVCMPAMSFGPVPKGLAAFSARHPDIHITHETHSAARIEDALTSNLFDVGIGMAPRDMAGLVSEGRFAFSCVCVMRPDHPLATQETVTATDICREAVVGINPDTEIGSQLRRLFESLPHSVSLRIETQTSIAACGLVEAGAGVAVVDPFTAAHLGRGGGLVSRRFSPIIPFDIHILRPERRVPSRAAQALIAELAAAMTSEEEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IN67</accession>
    <name>A8IN67_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dapF</name>
        <name evidence="10" type="ordered locus">AZC_3710</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3710"/>
    <dbReference type="EnsemblBacteria" id="BAF89708">
        <property type="protein sequence ID" value="BAF89708"/>
        <property type="gene ID" value="AZC_3710"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3710"/>
    <dbReference type="eggNOG" id="COG0253">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053306_1_0_5"/>
    <dbReference type="OMA" id="HVAMRVH"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="111"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="254"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="317" mass="33400" checksum="76112EEAF622F4FA" modified="2007-12-04" version="1">MPLPMGQHCDGRGGACAASRHIRSTVFWCLDAAPMLAHRPFVKMNGLGNEILVLDLRHEPEDVPAAAARALARPGVLPFDQAMVLYPPRRADTAAFVRILNSDGSESGACGNGTRCIAAYEAGRIGERHVLFESAAGLLDCVMQPDGQVTVDMGAPRLGWDAIPLARPVADTSAVQIEGFASLGPASMVSMGNPHAVFFVPDANAVDVEALGATLEHHPLFPERANISFAQVLSPDHILLHVWERGAGRTRACGTAACATGVSTARTGRTGRKVRVTLPGGDLVIDWRASDGHVLMTGPVALEFTGTLTSDMITEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IND7</accession>
    <name>A8IND7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cation efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_3738</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <keyword evidence="5 13" id="KW-0349">Heme</keyword>
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    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
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            <begin position="108"/>
            <end position="131"/>
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    </feature>
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        <location>
            <position position="85"/>
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        <ligand>
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        <source>
            <dbReference type="EMBL" id="BAF89741.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="133" mass="14602" checksum="68C6321DABCAE000" modified="2007-12-04" version="1">MADSPSRIVRPLSPHLQIYRPLPTMVMSIVHRATGIALYFGTVLLIWWLLAAASTPSAYGLFTSIAGSWIGRLVLFGYTWALIHHALGGIRHLIWDTIRGFGAQERVLLAKLTLVGSVTLTIIVWVIGLALKS</sequence>
</entry>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the BioY family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3757"/>
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    </dbReference>
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    <dbReference type="GO" id="GO:0015225">
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    <dbReference type="InterPro" id="IPR003784">
        <property type="entry name" value="BioY"/>
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    </dbReference>
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        <property type="entry name" value="BioY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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            <end position="53"/>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="85"/>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR016661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="185" mass="18349" checksum="5DA3C658D51DC0C8" modified="2007-12-04" version="1">MSKAAPLETRALVRIALFAALMGMLGLVPPIHLPFIAGVPITAQSLVVMMAGLTLGGRDGALAIALFLLVVALGAPLLSGGRGGLGVFFGPTAGFLAGYVAGAFATGWFAARLPGPRPLADFLGAVLGGIGVVYLIGVPAFAAIAQVPLAKALAGSAVFIPGDLLKAVVATLAARSLAQAGLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="4 5" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        </source>
    </evidence>
    <sequence length="753" mass="80252" checksum="579531D86E122F43" modified="2007-12-04" version="1">MTADERLHLFGSHFGTYEVEAGPDGRPRLLPFRHDPAPSPTGAAFLDLADHPLRVRHPMVRRGWLTAKGRPQGRGAERGRDDFVAVTWPEAARLVAGEIARVSGDYGNAAIFGGSYGWASAGRFHHAQSQLKRFLNLCGGFTSSVNTYSYGAAAVLLPHVIGREYQGATDTAPSWDQIAAHARLLISFGGFRLSNAQVEAGGTGQHRAEAALADVARAGCRIVVFSPTGADAPGLPGRVEHVPLRPGTDAAVLIAMAQVLLAEGRTDTEALARLTVGHEAFAAYLAGSPDGQPKTPEWAEGISGVPAATIRELARAYAQVPALVNLSWSLQRSRHGEQPYWAAIALAAMAGQVGRPGCGFAFGLTAVSSVGQPIRRLKGPAVTQGRNPVSSFIPVARITELLENPGGTLDYDGQRLALPNIRLVHWAGGNPFHHHQDLNRLAAAFRRPETVIVHESVWTATARHADIVLPASLPFERDDVAAASRDNWLIASRRVLATPPDVRSDHDMLALIARELGLDAAFTEGRSEEDWLRHLYAGYRDAHPELPDFDTFWARGYAGLDLGAPAPAPTTPLADFARDPDLHPLSTPSGRIEIGSSTIAAFGYDDCPGHPAWLEPEEWLGAPLAGTYPLHLLSPQPEHRLHSQLELAGPSQQAKVTGCEVLLLSPQDAAARGLAAGEQATVFNARGRALVAIGIDNRLSPGVAVLPTGGWYAPNEQGLDLGGNPNTLSSIRPTSRLAQGTAPNACLVEVVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPM4</accession>
    <name>A8IPM4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Basal-body rod modification protein FlgD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">flgD</name>
        <name evidence="6" type="ordered locus">AZC_0652</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Required for flagellar hook formation. May act as a scaffolding protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FlgD family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169183.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0652"/>
    <dbReference type="EnsemblBacteria" id="BAF86650">
        <property type="protein sequence ID" value="BAF86650"/>
        <property type="gene ID" value="AZC_0652"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0652"/>
    <dbReference type="eggNOG" id="COG1843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047535_1_3_5"/>
    <dbReference type="OMA" id="KYMESAD"/>
    <dbReference type="OrthoDB" id="709873at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005648">
        <property type="entry name" value="FlgD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03963">
        <property type="entry name" value="FlgD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="138" mass="13811" checksum="142CD61BBFBC0705" modified="2007-12-04" version="1">MTTVASTTSSTSTNTAAAASTAASNASTVDYNQFLQLLVAQLKNQDPTQPMDSTAYLSQLASFSQVEQQTNTNKKLDTLLSASALQSADAAIGKTVTSADGTVSGTVASVSLVSGGAPIATLKDGSKVTLDSSVSISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPR8</accession>
    <name>A8IPR8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Nitrite and sulfite reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_0681</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169212.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0681"/>
    <dbReference type="EnsemblBacteria" id="BAF86679">
        <property type="protein sequence ID" value="BAF86679"/>
        <property type="gene ID" value="AZC_0681"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0681"/>
    <dbReference type="eggNOG" id="COG0155">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015667_2_3_5"/>
    <dbReference type="OMA" id="HLTIDQA"/>
    <dbReference type="OrthoDB" id="1588103at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012798">
        <property type="entry name" value="Cbl_synth_CobG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005117">
        <property type="entry name" value="NiRdtase/SiRdtase_haem-b_fer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036136">
        <property type="entry name" value="Nit/Sulf_reduc_fer-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006067">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006066">
        <property type="entry name" value="NO2/SO3_Rdtase_FeS/sirohaem_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01077">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="2"/>
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    <dbReference type="Pfam" id="PF03460">
        <property type="entry name" value="NIR_SIR_ferr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00397">
        <property type="entry name" value="SIROHAEM"/>
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        <property type="entry name" value="SSF55124"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02435">
        <property type="entry name" value="CobG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00365">
        <property type="entry name" value="NIR_SIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NIR_SIR_ferr" evidence="8">
        <location>
            <begin position="110"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="7">
        <location>
            <begin position="180"/>
            <end position="338"/>
        </location>
    </feature>
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        <location>
            <begin position="362"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="NIR_SIR" evidence="7">
        <location>
            <begin position="442"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="589" mass="62801" checksum="E11317FCED12AE9F" modified="2007-12-04" version="1">MSGDFTVDQKRYLEGFMSGAQVARAGRAPGGGSPATAEPTGPDAPSLKAMARTEAEGKKLCPEEKAKREEMGLDAWPRMEEAAREGVYPKGPDILRWKYHGLFYVAPAQDSFMCRLRMPNGILTHWQFRGIADIAEIHGGGYADVTTRANLQIREIPATDGVILLEKLVDLGLTAKGSGGDNIRNVTGTPTAGIDPQELLDTRPYAKAWHHHILNTRTLYGLPRKFNVAFDGAGQIGALEDTNDIGFQAVEVKEGFGVEPGVWFRLALGGITGHKDFARDTGVILPPADATKVADAIIRVFIDTGDRTDRKKARLKYVLDALGFDGFLKKVEERLGAPFVRVPADAVKPRPEADRMAHLGVRPQKQAGLNWIGIGVPVGRMTAAQMRGLADIAQNLGDGDLRLTVWQNVLVSGVPDARVTVAKAAITALGLTADADALQAGIVACTGAAGCRFGNADTKATARAIAAYCGPRVALDSPVNIHVTGCHNSCAQHYIGDIGLIGARVAINEDGDTVDGYNLLVGGGFGTEAAIAQELFEQVKAEDAPALVERLLSGWTAQRLPGETFAAFTRRLGPAALKSLVETAMERAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Dihydrodipicolinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0731</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169262.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0731"/>
    <dbReference type="EnsemblBacteria" id="BAF86729">
        <property type="protein sequence ID" value="BAF86729"/>
        <property type="gene ID" value="AZC_0731"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0731"/>
    <dbReference type="eggNOG" id="COG0329">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_049343_4_0_5"/>
    <dbReference type="OMA" id="CGNGGLF"/>
    <dbReference type="OrthoDB" id="1438588at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="312" mass="33774" checksum="0FBF79CFB540E639" modified="2007-12-04" version="1">MRLTADASGLFPIAPTPFHADGRIDEASLDTLMERYIAAGATGVTVLGIMGEAPKLEPDESLNIAARFAKGMAGLPVIVGVSAPGFAAMRWLARNAMDKGAAGVMIAPVPSLRTDDQIITYYRQAIEAIGTDIPFVIQDYPLTLSVQMTPKVIRAIVEEHPSCVMLKHEDWPGLEKISTLRGFQKEGTMRPISILTGNGGMFLDFEMERGADGAMTGYAFPEMLSDVVKLQKAGKRDEAHDLFDAHLPLLRYEQQQGVGLATRKYVLMKRGFISSDAQRKPGGTLSATARAEVDYLLARLAKIDARALPLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQB9</accession>
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        <submittedName>
            <fullName evidence="8">Aldehyde dehydrogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0765</name>
    </gene>
    <organism evidence="8 9">
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_0765"/>
    <dbReference type="EnsemblBacteria" id="BAF86763">
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    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_005391_5_1_5"/>
    <dbReference type="OMA" id="WHKLIEQ"/>
    <dbReference type="OrthoDB" id="384611at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
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        <property type="entry name" value="Ald_DH_C"/>
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        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
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        <property type="entry name" value="Succ_semiAld_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSADH"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
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    </dbReference>
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        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0630">Potassium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="7">
        <location>
            <begin position="20"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="484" mass="51332" checksum="6ABF6508855D079E" modified="2007-12-04" version="1">MLHLKNPSLHQDACLINGAWRKAASNAHIVVHNPANGALVGHVPDLSASEVREAVDAAQAAFGPWSRKAAKERSALLRRWFDLIIANADDLAALMTAEQGKPLAEAKGEVVYAASFIEWFAEEGKRVYGDVIPAPTTDKRLIVLKQPVGVTAAITPWNFPAAMITRKAAPALAAGCVMIIKPAEQTPLTALALGVLAQEAGIPAGVIQVVTGDAREVGGVLTGSDVVRKLSFTGSTEVGRILMSQCAPTIKRLSLELGGNAPFIVFDDADLEAAVEGAIASKYRNAGQTCVCANRFYVQSSIYDAFAARLAERVKQLPVGVGTEPGVLIGPLIDEDAIAKVKAHVADAVEKGATIALGGKMHALGGTFYEPTVLTGVTSDMRVAREETFGPVAPLFRFETEEEAIFLANNTEFGLAAYFFTENARRAWRVAEGLEYGMVGHNTGLISNEVAPFGGVKQSGIGREGSKYGIEEYLEIKYLCSAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="6">Transcriptional regulator</fullName>
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    <gene>
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        <name evidence="6" type="ordered locus">AZC_1061</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1061"/>
    <dbReference type="EnsemblBacteria" id="BAF87059">
        <property type="protein sequence ID" value="BAF87059"/>
        <property type="gene ID" value="AZC_1061"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1061"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_40_0_5"/>
    <dbReference type="OMA" id="HIWSMSH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
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    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
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    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTHTETR"/>
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        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="32"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="212" mass="21794" checksum="9B380F2690C556FB" modified="2007-12-04" version="1">MSRHAPVAPMAVCAMHGCMTERTPPRRGYHHGNLKDALLDAARDLVATEGPAGVTLAEASRRAGVSPAAPYRHFKDRDALMAALAERGFAQFADELAQAFGDGAPDPASAFLRVGDAYLAFARREPGLYGAMFTVCPPGRETAQGGRAFALLAASAGQAAGVERLPQGAILSIWALAHGAATLAASGHLDEAEAHAALVAGVSGILKGARSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQX3</accession>
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        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
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        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="7" type="ordered locus">AZC_1072</name>
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
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        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
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            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
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        <cofactor evidence="5">
            <name>Mg(2+)</name>
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    <comment type="cofactor">
        <cofactor evidence="5">
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        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
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    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
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        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
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            <begin position="18"/>
            <end position="212"/>
        </location>
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    <feature type="region of interest" description="Substrate binding" evidence="5">
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            <begin position="12"/>
            <end position="14"/>
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            <end position="50"/>
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    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
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            <begin position="175"/>
            <end position="178"/>
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    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
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        <ligand>
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    <feature type="binding site" evidence="5">
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            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
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    <feature type="binding site" evidence="5">
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            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        <location>
            <position position="49"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:49883"/>
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    <feature type="binding site" evidence="5">
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        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
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    <feature type="binding site" evidence="5">
        <location>
            <position position="92"/>
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        <ligand>
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    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
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        <ligand>
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            <position position="212"/>
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        <ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
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    <evidence type="ECO:0000313" key="7">
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    </evidence>
    <evidence type="ECO:0000313" key="8">
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="InterPro" id="IPR022473">
        <property type="entry name" value="ABC_trnsptr_Choline_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03415">
        <property type="entry name" value="ABC_choXWV_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="21"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="75"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="407" mass="44140" checksum="E878DB6E21012A78" modified="2007-12-04" version="1">MTAHSMTTEAISTAGTTAVEFRNVDIVFGHKPERAFPMMDAGGTRDAILEATGCVLGAAGVNLTIGRGEICVLMGLSGSGKSTILRAINRLNRTARGEVFVRHDGTLIDVARCDERMLRDIRMRTVSMVFQQFGLLPWRTVRENVGFGLELRGVGAAERNRLVDEKLAMVGLSKWADKYAHELSGGMQQRVGLARAFATDADILLMDEPFSALDPLIRDKLQDELLDLQQRIQKTIVFVSHDLDEALKIGNTIAIMEGGRIVQAGTAEDILLRPANDYVADFVKHMNPLNVLRGNAVMTPASALRREGGTILLGREGHVRVVIDADGRPISVLLNGREGRLGAADPTSGAVEPAVDLIVAPLDLKLKAAIALKCQTDHPILLVDQLGRLAGLCDDEEIYRGLLRRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRP3</accession>
    <name>A8HRP3_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">Putative allophanate hydrolase subunit 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ahs1</name>
        <name evidence="6" type="ordered locus">AZC_4073</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172593.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4073"/>
    <dbReference type="EnsemblBacteria" id="BAF90071">
        <property type="protein sequence ID" value="BAF90071"/>
        <property type="gene ID" value="AZC_4073"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4073"/>
    <dbReference type="eggNOG" id="COG2049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020207_1_0_5"/>
    <dbReference type="OMA" id="MPWMLAA"/>
    <dbReference type="OrthoDB" id="1848526at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010016">
        <property type="entry name" value="KipI_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34698">
        <property type="entry name" value="PTHR34698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="AHS1" evidence="5">
        <location>
            <begin position="10"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="246" mass="26839" checksum="1FA0D233ADA03536" modified="2007-12-04" version="1">MIEGEVYAAPRFLDSGETALVVEFGRAVEPEISDRVLALDAALVARALPGVRESVPTYRSLMVHYDPLVISRATLVGEIEAMVNAPRAASGPVTRWVLPCCYDPEYGEDIGEVSRMTGLSEEKVVALHAGAVFRVYMYGFAPGFCYLGGLPKELAVSRRTRPRPPHPPNTTLIGGGLAIVTTFSMPTGWWLMGRTPERMFAAERNPAFLVAVGDELKFEPVDRDTFLALDARAASGEVVARREIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS45</accession>
    <name>A8HS45_AZOC5</name>
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        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ordered locus">AZC_4138</name>
    </gene>
    <organism evidence="9 10">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
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        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_4138"/>
    <dbReference type="EnsemblBacteria" id="BAF90136">
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    <dbReference type="eggNOG" id="COG0014">
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    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    </dbReference>
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        <property type="term" value="F:NADP binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
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        <property type="entry name" value="Ald_DH_C"/>
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        <property type="entry name" value="Ald_DH_N"/>
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    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="30"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="439" mass="45393" checksum="115186C4BB862B98" modified="2007-12-04" version="1">MAMPHAARLSVAASAGSAAPVDVPAVLSQMGRAARAAARTLALAPAEQKTAALKAAAARIRAATPEILAANADDMARARADGMSGAFQDRLALTESRIEAIAAGVEMVAGLPDPVGAVTESWTRPNGLVIERVRTPLGVIGVIYESRPNVTADAAALCVRAGNAVILRGGSDSLGSSGAIHKAFVAGLVDAGLSADCVQFVPFSDRTAVGLMLGGLDGNLDVIVPRGGKGLVARVQSEARVPVFAHLDGIVHVYVHAAADLDMAKTVLLNAKMRRTGICGAAETLLVDEKVAASQLKPLVEMLLDAGCEVRGDAAAQAVDPRVKPAVDADWDTEYEDAIISVKLVPDLAAAIDHIETHGSHHTDSIITRDEAAAARFLREVDSAIVMHNASTQFADGGEFGFGAEIGIATGRMHARGPVGAEQLTSFKYRVHGNGQTRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSL6</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90193">
        <property type="protein sequence ID" value="BAF90193"/>
        <property type="gene ID" value="AZC_4195"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4195"/>
    <dbReference type="eggNOG" id="ENOG5033P23">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1407297_0_0_5"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="HXXEE"/>
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        <property type="entry name" value="HXXEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="188" mass="19884" checksum="D745AA24CC80AD4F" modified="2007-12-04" version="1">MGGMGTSWLAKHWVAGAAFMAGALLLVLPGIVPDPALRLVYLASPLYMLHQIEEHAGDRFRTYVNDVVFGGVQALSVADVLVINLPGVWGINLLAFYAALAFGPGWGLAAAYLILVNGIAHVGMALRFRGYNPGLVTGALAFIPFGVLSLLLIPARPVEHVVGLAISLVIHAAIIVRVKANTRQAVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTA6</accession>
    <name>A8HTA6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0815</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <evidence type="ECO:0000313" key="2">
        <source>
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    <sequence length="152" mass="16830" checksum="11FF85BB32D94443" modified="2007-12-04" version="1">MTVADDETLPDAPALVSAERLLKEADALFARNQPVGVIWPNSKDVLDLAPFVDRLAVVALVFPKFRDGRAYTQARLLRERLGYKGELRAIGNVLRDQFLLMVRCGFDALDVAKEADAQAVEKELKTYSVFYQPTGDGRPTPLRARLAAARSV</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit A family.</text>
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        <property type="protein sequence ID" value="BAF86992"/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    <sequence length="236" mass="24840" checksum="8B78C313D8A45DB9" modified="2007-12-04" version="1">MDKTVGDLATAVSEIGDGATVMIGGFGGAGAPVELIHALIDKGPKGLTVVNNNAGNGRIGIAAMIAAGMVRKLICSFPRAADASAFNERYLAGELELELVPQGTLAERIRAGGAGIPAFYTPTSYGTELAEGKPVAEFDGRPYVQERWLKADFALVKAHLGDPYGNLTYNKAARNFSPLMCMAAAKTIVQVSRIVPPGDIDPEHVITPGIFVDRVVEVADARQEEDLIRAGAAYND</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4297"/>
    <dbReference type="EnsemblBacteria" id="BAF90295">
        <property type="protein sequence ID" value="BAF90295"/>
        <property type="gene ID" value="AZC_4297"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4297"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_1_2_5"/>
    <dbReference type="OMA" id="GNTYRES"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07572">
        <property type="entry name" value="nit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045254">
        <property type="entry name" value="Nit1/2_C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="4">
        <location>
            <begin position="33"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="316" mass="34106" checksum="457B4603E934391D" modified="2007-12-04" version="1">MAAGGAMPISPPSGTPPVKRDRDMTSTAETARLRVGLVQLRSGRDMDANIEIATALIREAARDGARYVQTPEVTHLMEMDRAVLFTKLKDEPLDPGLRAFQALAKELGIHLHVGSLAVRVSETKAANRGFLIGPDGEIAARYDKIHMFDVDLPGGESYRESNAYRPGERAVLGHVDEFKLGMSICYDLRFPALYRALAESGASVLTAPSAFTRPTGEAHWHILLRARAIETGAYMLAAAQGGKHENGRETYGHSLVVDPWGRVIAEGGTEPGVILAELDIAEVEAARSRVPSLRNGRRFELADVPAGRLHVVGAAT</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVS4</accession>
    <name>HTPG_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chaperone protein HtpG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Heat shock protein HtpG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">High temperature protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">htpG</name>
        <name type="ordered locus">AZC_4352</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Molecular chaperone. Has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172872.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HVS4"/>
    <dbReference type="SMR" id="A8HVS4"/>
    <dbReference type="STRING" id="438753.AZC_4352"/>
    <dbReference type="EnsemblBacteria" id="BAF90350">
        <property type="protein sequence ID" value="BAF90350"/>
        <property type="gene ID" value="AZC_4352"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4352"/>
    <dbReference type="eggNOG" id="COG0326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006684_3_0_5"/>
    <dbReference type="OMA" id="MRRMKEM"/>
    <dbReference type="OrthoDB" id="246194at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_1000072454" description="Chaperone protein HtpG">
        <location>
            <begin position="1"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="A; substrate-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="B" evidence="1">
        <location>
            <begin position="337"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="C" evidence="1">
        <location>
            <begin position="557"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00505"/>
        </source>
    </evidence>
    <sequence length="635" mass="69353" checksum="4D927EF2CB9355C2" modified="2007-12-04" version="1">MTTAEAAAPESRTFEADVAKLLHLMVHSVYSDKDVFLRELISNAADACEKLRYEAITTPALLGEDARPRITLAIDAEGGRLTVEDNGIGMSRDEMVEALGTIARSGTKAFMERIEAAAGGEKAELIGQFGVGFYSAFMVAEKVDVISRRAGADTANIWSSDGKGAYTVGEIDVAQAPARGTRVVLHLNEDGKAYADRFRIERIVKEQSGHVPVPIYIVEKLDAEPEEIADGVALWTKSKSDISAEDYADFYRSVAGQFDQPALTVHFRAEGRHEYTALVFVPSTKPFDLFEPERTGRVKLYVKRVFITDDAELLPRYLRFVRGVVDSADLPLNLSREMLQDSAILAAIRKGVTGRVLTELEKLAQSDAEAYAGIWSNFGAVLKEGLYEDYERRAQLLNLARFKTTTSGTAADTGWRTLKDYVADLKENQTAIYYITGDLARVEHAPQLEGFRARGVEVLLLPDQVDSFWVTAGVDYEGKPFKSVTQGAADLSLIPLPKSDEAETPEPEAKDTGDFIAFVKETLGDQVADVRASDRLTTSAVCLVAPESGIDRRLEKLLASAGRLGDAAKPVLEINPRHPLVAALAAHGASDSNFRADAAHLLLDQARVLDGDQPSDPQAFAERLMRVMQRGLPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVX5</accession>
    <name>A8HVX5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4369</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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                <person name="Akiba N."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1600"/>
    <dbReference type="EnsemblBacteria" id="BAF87598">
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        <property type="gene ID" value="AZC_1600"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1600"/>
    <dbReference type="eggNOG" id="ENOG5033072">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OrthoDB" id="1804282at2"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
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    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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            <begin position="6"/>
            <end position="29"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87598.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="115" mass="12193" checksum="C0F6880711505E5A" modified="2007-12-04" version="1">MIYDNALVAALIVIVVGFLPTEIWRWLAVVAGRRVEAGSELFHWIKAVATALLAAVVGRLVFMPTGALAEVPLSLRLASVGAGVLAFLLIRRSVLAGVVAAQVVLLGGIWWLGIH</sequence>
</entry>
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        <alternativeName>
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        <name evidence="9" type="ordered locus">AZC_4472</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4472"/>
    <dbReference type="EnsemblBacteria" id="BAF90470">
        <property type="protein sequence ID" value="BAF90470"/>
        <property type="gene ID" value="AZC_4472"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4472"/>
    <dbReference type="eggNOG" id="COG0313">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044779_2_1_5"/>
    <dbReference type="OMA" id="RTMVFFE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
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        <property type="entry name" value="4pyrrole_Mease_sub2"/>
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        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
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        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
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    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
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    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="8">
        <location>
            <begin position="80"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="355" mass="37032" checksum="E31DCD8BED24E6B3" modified="2007-12-04" version="1">MAAERARCSDARARTMIAAMTQSPARASHDAAEDITAPLTGDLPADDTTDLPDLEPGTPGEKAFTLFGQTVQARRLDTGLHVVATPIGNLGDITVRALETLAGAGLIACEDTRMTRRLLDRYGIATPLVPYHDHNGASMRPRLLAKLAAGEAVALVSDAGTPLVSDPGYKLVVEAAAAGFRIHPLPGASAMLAALVTAGLPTDRFLFDGFLPQKGGQRRNRIAELKALPSTLVLYETGPRLAESLADLAEGLGDRPAAVCRELTKAFEEVRRGPLSQLAAHYAAAGAPKGEIVLVIGPPLEEPAADDDVDAALTRALAEHSLKDAVAAVTAATGRPKREVYARALALTKGEDGPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYS6</accession>
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            <fullName evidence="9">Methyl-accepting chemotaxis sensory transducer</fullName>
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    <organism evidence="9 10">
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
        <property type="entry name" value="SSF141868"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50883">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="358"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="503"/>
            <end position="758"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="772" mass="84228" checksum="738EFD38A6F8F5FA" modified="2007-12-04" version="1">MSASRLRPMTGEFIRVEDEAAFQRQRFPETVRHARLVLGVAFGAGVLLLLNDLRIIGEPIFPVVLALRLSLLAYTVASFRWAARMADFPRLERLIVAWQWLTGSIIALIVYLKSNISLPISLVLPVIFYLAVPVSFRWRVLNGSVGSLLLLLAYATDPDDPLSLLSMGIWVLVLNAVLILLVLRDNRMARLSWCAIEAERAALASTARSHEMVEKTFLAAPIPMVVADIESGRILRMNEAGQRYFQQGPEDAPTTLGDLHLEPDVQKQMMENLRRTGEISNFEARIGQGDAPARTALIGGSMLEVNGRPAVVAGLMDITDRLMAEDKVRQAALHDALTGLSNRAAFQLSLEAACAAFNSVCLLLVDLDSLKDVNDTYGHDAGDALLVETARRLGQQVEERVGGRGFVARLGGDEFVVLLAGVRLPEAIDMAETLIAGLRAPIWYGGRSLIARASVGVAERMGETQTSGELMKNADLALYAAKSQGRNRAVVYAPQMRWAMQERVALHSALTEAASSRAIVPFYQPKVSLVTGRVVGFEALMRWRRGPQAFLAPAAFASAFQDPELAVLVGDAMIQRVAADVRQLLDRGVVLGRIALNLSPAQFTHTDVGRHLLERFDEARVGAEHFDVEVTETVFLGRRADHVRPILDEICGAGMHIALDDFGTGYAALSHLKQLPIDTLKIDQSFVLDVEADRFDAAIVCSVIELGRNLGLQVVAEGVETIGQARFLAARGCEVAQGFLYAHPMSAEHMADFLAAESDAVIAERLRALDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ64</accession>
    <name>A8HZ64_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative penicillin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_4544</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4544"/>
    <dbReference type="EnsemblBacteria" id="BAF90542">
        <property type="protein sequence ID" value="BAF90542"/>
        <property type="gene ID" value="AZC_4544"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4544"/>
    <dbReference type="eggNOG" id="COG0768">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009289_6_2_5"/>
    <dbReference type="OMA" id="HGKEEYY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="151"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="325"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="655" mass="71903" checksum="B47350362B50678F" modified="2007-12-04" version="1">MIPSFKVPAFLKTSAQGLGRAGSATGSVLGRAGGSVGRFILNLLWQVVRFILMTIYGMIRWVVLRIYRLCRWFVMRIIGLVRFTYRASIIIVRGMLGLDRADQETVTRARLKLIIAAFSFVFLAIALRLAFLGVTSDPNGVRGGGSEAVASARPDIVDRNGEIIAIDVKSPSLFAEPKRLIDPDETLEGLLKVLPDLDVNEVRNRLNSKKGFAWLKREITPAQQRAIYRLGFPGIGFVRENRRIYPDGPSFSHVVGNVNVDNQGIAGLEKYIDGRGLAELHLAGLATDRQQEPVALSMDVRVQHTLRDELLKAREKFKAKAAMGLVTNVRTGEIVAMVSLPDFDPNLNGDPRSDAYLNRLTTGVFEMGSTFKSLSFAMALDSGKISLSNSFDARAPLSFGRFAIHDFHPEGRVLSLPEIFIYSSNIGTAKMVLSLGVDAHKAFLKKMGQMDRLRTELPESAEPIVPKRWGELNSATIAFGHGIAVAPLQAVMAVNSMVNGGYLIPPTFLKRTEDDAMKVATRVLKPETSDKMRYLLRLNVEKGSGKKADMVGYNVGAKTGTAEKVVGGRYAKNKLLTSFTAVFPMDRPQYLLLVMLDEPQPTPETHGYATSGWNAAPVAGKIVERIAPMLNVAPRAPLSADQLLRDIGQKVADRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZD8</accession>
    <name>A8HZD8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoacyl-(Acyl-carrier protein) reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4571</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
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                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
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                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <evidence type="ECO:0000256" key="1">
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    <sequence length="300" mass="32902" checksum="CA990AA0602681D2" modified="2007-12-04" version="1">MSAPLTPCPPPNPDPSLPARRPPAGACDAHCHIYGPFARFPLPDDRSFTPSEVPETALRALHERMGISRAILVQSQGHGFDHRPLLDALEREPARYRGVALIRPDTSDAEIRTYDRAGICGVRFSFLSHLGGAPDLEAVAAAARRVAGLGWHVAIHVTGTDIARYRDFISGLPTRVVIDHMARPDIRQDLAPVREALFRLLDTGRVWVKLSGADRLSHAGPPYEDVVPYARSLLDHAPERALWGSDWPHVNLSGPMPDDGTLVDFVDHIAITPALKQRLLVENPETFFGFPASRNDNLSG</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="9 10" key="3">
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <dbReference type="PIRSF" id="PIRSF001589">
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        <property type="entry name" value="RHODANESE_3"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="213"/>
        </location>
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    <feature type="domain" description="Rhodanese" evidence="7">
        <location>
            <begin position="259"/>
            <end position="306"/>
        </location>
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    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
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        <ligand>
            <name>L-glutamine</name>
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    <feature type="binding site" evidence="6">
        <location>
            <position position="265"/>
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        <ligand>
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        <ligand>
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        <ligand>
            <name>ATP</name>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51278"/>
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        <source>
            <dbReference type="EMBL" id="BAF87363.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="589" mass="65292" checksum="C1E0694ED64A4894" modified="2007-12-04" version="1">MCGICGEVNRNGSVRMAPLEAMSDALSPRGPDGFGLLAQGDVALAHRRLSILDLKATSQQPMVDSQLGLAIAFNGCIYNFRDLRQDLKAKGYTFFSEGDTEVILKAYHAWGADCVLRLKGMFAFAIWEMWTGRVVLARDRLGIKPLYLADVGSSLRFASTLPALLAGGGVDTAIDPVGLHHYMSFHSVVPAPRTILRGVRKLPPATLLTLEPDCQRSERQYWSVRMGGDTDTDDMGEEEWRETLIHCLLRAVERRTVSDVPVGVLLSGGLDSSLLVALLAQLGHEDIRTFSVGFEAVGGLKGDEFEYSDLMARAYGTDHTKIVISPERVLSALPGVIGAMSEPMMSHDCVGFYLLAEEVSRHVKVVQSGQGADETFAGYHWHEKMLTAADPLDDYARLYFDRDHAEMAHALSPDMISGDHSRIFVKDFFDRCGETSPINKTLQIDTEIMLVDDPVKRVDNMTMAFGLETRVPFLDHEMVELATRIPSELKVKSGGKHILKEAARRILPPEVVDRPKGYFPVPALKYIRGPYLDFARDVLNQQAARDRGIFRQDYVEGLLGDPEGSLTPKGHSKLWQVTVLEHWLQTHGV</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1379"/>
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        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="269" mass="28193" checksum="CFFBBB21C966BD53" modified="2007-12-04" version="1">MSTKGTAVVTGASSGIGAIYADRLARRGYDLVIVARNAERLEKQAEALRARHGVAVRTLSADLTDKSGLRQVEDLLRNDTSVSLLVNNAGFGGAGELLQSDVDRMEEMVDVNVTAVMRLAYAAAPGFAARGAGAIINIASIVAIGPEILNGVYGGTKAFVLAFSQSLHKELSPKGVQVQVVLPGATATDFWDTAGVPVSHLPTEWVMTAENLVDAALLGFERGEFASIPSLQDGAEWEAYETARQAMLPHLSSSAVAPRYRAGADAGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
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        <name evidence="12" type="ordered locus">AZC_1392</name>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="12 13" key="5">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="340"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="479"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="728"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="845" mass="91541" checksum="8718915F40F43E88" modified="2007-12-04" version="1">MTGSALFILEPGSNAEQSFILGGRVGRSTPDLDDIFPGDSAMAKLMRQHDWSATPLGCPSTWPDGLTIPLRMLLTSRFEMWLGWGEDLRFFYNDAYIPTLGIKHPSMLGRPFREVWAEVYDDVADQVAKVRAGEATWNDSLMLILERSGYPEETYHSFSYSPLYGAERAVEGLLCIVTEVTRPVISDRRLSTLRQLGTALVGVTSRDEVSLAVCAVLGANRRDFPFALLFLGDGSTRQAVACSADAAHLLNGPWPDDPPANGISFALPPDVDYPAGDWPARPREALSVPIPGAAGRPAAGFLILGLNPFRQRGENVADLANLLAGQISGALANVATLATERRRADRIWTNSRDLLVTVDAAGVFQSVSPSWTRILKHPIEAVVGRSFSDFIHPDDLEPAHQALRKAMSGSYLTGLENRFQTADGEVRHISWNTAMEDGLVYGYGRDVTEEKAKAAALANAEEALRHAQKMEAVGQLTGGIAHDFNNLLTGIIGSLDLVRRRIKPDWPSDVDRFLTVATSSAERAASLTQRLLAFARRQSLDPQPVQAHQLVVGMLDLIKKSIGELIVLRIETEEDLWNARCDPNQLESSVLNLAINSRDAMPDGGTLTIRTENVRVEPADLGRVALPAPGDYVLLQVEDTGHGMPAHVISKAFEPFFTTKPLGKGTGLGLSMIYGFAQQSGGTVLIESVEQQGTVVSLYIPRSREDARPIVPAGGDADRAEAIKHAATILIVEDEPAVRLLVTESLGALGYETLVASTGPDGLRILQSDQPIDLLLTDVGLPGLNGRQLADAARVTRPNLKVLFVTGYVHDSGLYEDGLEPGMAVVTKPFDIDKLAKRVAELIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2P5</accession>
    <name>A8I2P5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PepSY amd peptidase M4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1912</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170440.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1912"/>
    <dbReference type="EnsemblBacteria" id="BAF87910">
        <property type="protein sequence ID" value="BAF87910"/>
        <property type="gene ID" value="AZC_1912"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1912"/>
    <dbReference type="eggNOG" id="COG3182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031962_3_2_5"/>
    <dbReference type="OMA" id="LAWRWHF"/>
    <dbReference type="OrthoDB" id="1656356at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34219">
        <property type="entry name" value="PTHR34219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="425"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="465" mass="49497" checksum="663B09DCA8D7BE76" modified="2007-12-04" version="1">MRDAVWSATAFYRAVWRWHFYAGLVCAPFLVILAVTGAIYLFNDEINDLVYPNLRLVPASATEIPLSEIARAAAASVPGGTVTRIDTPTAAGRSVQVFVAPPSGAPLRVFVDPGSGKVLGSYVYTHTLVGFADVAHGSLMLGPLGDAVVELAACWGFILTVTGLFLWWPRGGKPPLFRPRSGLRKRAFWKDWHSAVGFWSALLVLFLILTGLPWAGIWGDLLRAGADVAGIGYPATFRTHGATLQSHLTIKEASDGAAPWTLENEPAPSSQAADPHAHHHGTAPAPRAAGTPQPIGLDAAAQVIADAGMSAPYRLSLPRDALGTYIAFVYPDQPEGQRTLYIDQYSGQVLGDIGFGDYGPMAKAVELGVQLHMGNYFGLPNQLVMLLPCLAIVFLCISGPIMWWRRRPAGRLGAPKPIARPTLRVLALIVLALCLVFPLAGVSLIAVLGLDLLAGRIAEGLGPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2T7</accession>
    <name>A8I2T7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1933</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
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        <location>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <sequence length="251" mass="27922" checksum="C8B67703D6883F30" modified="2007-12-04" version="1">MSPRPRTRRDTPASLADQAVDRLRDMIVFLDLAPGAVLSERRLVEALGASRTPIREALKQLSAEGLVLLRPNRPAMVAPLDPEELRHLFEVEVALESFAASLAATRMAEADFDRLARYQSEMEERHAAGDRVSYIRINRKIHLLIVAGSGNPALSEVHARLIGRLQRARNIGLSSLGRVEESIEEHRQILAALRRRDGEMTRMLMARHVARTGGLFADYCAAARIESSEVRAAGRRRLGSMARPLPERGNV</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF87985">
        <property type="protein sequence ID" value="BAF87985"/>
        <property type="gene ID" value="AZC_1987"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <source>
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        <source>
            <dbReference type="EMBL" id="BAF87985.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="386" mass="40755" checksum="452F4E69F6063DA7" modified="2007-12-04" version="1">MPVVNRIADLADEITAWRRDLHAHPELLYDLPRTSALVAERLTAFGCDEVVRGIGGSGVVGLIRGKGPGRTIALRADMDALPLTEITGAPYASTTPGKMHACGHDGHTAMLLGAAKILAETRNFSGTVALVFQPAEEGGAGAKAMIDDGLFERFGIEEIYGMHNMPGIALGAFGMCHGPIMAAADVIHIDIEGRGAHAAQPHDGVDPVLVGSHIVLAAQSLVSRTIDPLKSAVVSITQFNAGTTDNIIPQTAHLCGTVRTYDPEVRDLIESRLAQIAETTAAVFGAKATLRYVRGYPATRNHPAQTDFAARVASDVAGPAAVDTAMPPRMGAEDFSFFLEQRPGAFVFIGNGDTAGLHNPAYDFDDRAIANGTSYWVRLVEMGLPA</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        </source>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Backer P.D."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF88318">
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        <property type="gene ID" value="AZC_2320"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2320"/>
    <dbReference type="eggNOG" id="COG3693">
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    <dbReference type="OMA" id="LRSTYWW"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF14415">
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        </location>
    </feature>
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        <location>
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        </location>
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        </location>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14415"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88318.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="350" mass="38669" checksum="3603C0D5BB6B7011" modified="2007-12-04" version="1">MIDNHKTFGRCTARLLIAGLLAAAAGTPALANDSTAALSAGGLIMVPNLDIEMASEDLFISEQEVRVRYVFRNTAKQDQTVLVAFPMPDITIRESLNITIPNDASDNFLDFKTTVDGKPVQTQLEQRALALEIDRTAMLRDLKIPLAPYLKQTQAALDALPQDKWKEFEALGLGMVDEYEAGKGPERHLAPQWTLKSTYYWSQTFPAGKALVVEHKYRPSVGMSAGTLIGLKLKDNEYAAEEQRQQMDQFCVDQAFLNGVSKASKASKNSGEVPFSDARIHYILQTGGNWSGGTIRDFKLTVDKGASENLVSFCGKDVKKISPTQFQMTAKDFYPARNLGILILKPYPKQ</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2392"/>
    <dbReference type="EnsemblBacteria" id="BAF88390">
        <property type="protein sequence ID" value="BAF88390"/>
        <property type="gene ID" value="AZC_2392"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2392"/>
    <dbReference type="eggNOG" id="COG0668">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013626_0_0_5"/>
    <dbReference type="OMA" id="SAMMQDD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LSM_dom_sf"/>
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        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045276">
        <property type="entry name" value="YbiO_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30460">
        <property type="entry name" value="PTHR30460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724171" evidence="10">
        <location>
            <begin position="26"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="133"/>
            <end position="159"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="180"/>
            <end position="203"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="232"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="253"/>
            <end position="274"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="307"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="382"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="453"/>
            <end position="473"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="494"/>
            <end position="516"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="544"/>
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    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="739"/>
            <end position="780"/>
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        <source>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="BAF88390.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="780" mass="84954" checksum="2850F71C7BA6BBCF" modified="2007-12-04" version="1">MMQRCAMIRALCLALCLLFSSASFAQTPAAPAGSVTSPATAAPKSEDSLKVLLDTLSDDKARADFTARLRALLEARDATTGTPAADDWVAGTTRSLSDFSSGVLTVVGEIENLPTQMSEAVEALRDPAALRRIAWAAGTVVLALAAAFAAEWLASLLLARPRRAIERRAGDLLVIRLFLILVRAVLLALPIIAFAAAAFAVLGAVEMSFVVRLAVVTLVNASVMARAIIAFGHAVLSPESRRLRLPPLDDESAAYGFLWVGRFANTVVYGYFLLRAAWILGLSTSAYAFLLDVLGLLVAGMAIVFLLQIRASVAGWLRASGEAGTSLTRLRNQVADFWHLLAIAYVVAGYFVWVLDVRDGFAFLAQATALSVLAIVAARFAARLLQRGFGMIFHLSPEVRRQYPLLEARANRYLPILRQVFQGLLAVLTLLVLLEIWGGSPFAWLASDNGQRLLSRCISIGVVALSALIAWEVGTAFAERLIRRHPSSSRLKTLLPFLQNGFRVVLLTLVGLILLSEIGVNIAPLLAGAGVFGLAIGFGAQTLVKDVITGIFILMEDTLSVGDVVEVGAHSGLVEKITIRTVHMRDFDGNVHSIPFSEVQTIKNMSKGFAYAVVDVMVSYRENIDEALKTMAEVAEDMRRAGPLAETIIEPFEVVGVEGLQESAVWLRGRFKTRPLGQWNVKREFYRRIKAAFDARGIEIPLPQRRLFFGTDKAGNAPPLHILTDANALQVQEDRRRVAEAARAARRPGPHIEEHPGARERRDDEAQEILPTVERHPERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6V7</accession>
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        <submittedName>
            <fullName evidence="3">Histone deacetylase family protein</fullName>
        </submittedName>
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    <gene>
        <name evidence="3" type="ordered locus">AZC_2049</name>
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    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_2049"/>
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        <property type="gene ID" value="AZC_2049"/>
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            <end position="335"/>
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        <source>
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    <evidence type="ECO:0000259" key="2">
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
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            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="BPD_transp_1_N"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
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        <location>
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            <end position="27"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="122"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="95"/>
            <end position="304"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88077.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="313" mass="33623" checksum="6D9C042731F47386" modified="2007-12-04" version="1">MLAYVLRRVLAAIPVMGVVALFVFLLLRLTPGDPAAIIAGDTATPAQLEAIRTSLGLDKPIPVQFLTWISQLAHGDLGTSLISKTPVTTLIGQRLGPTLNLALVTMVLSILIAVPMGVLAAWKHGTLIDNLVMALCVLGFSVPVFVIGYVLIQVFAINLRWFPVQGFSTIANGIGPFAQRATLPAFTLASIYVALIARMTRASLLDVLGEDYIRTARAKGVAERIVLFRHALRNSAVPILTVIGTGFALLISGVVVTESVFNIPGLGRLIVDAVLARDYPVIQGLILLTSGIYVFINLMVDLSYSLLDPRIRY</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="evidence" value="ECO:0007669"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF88110.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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    </evidence>
    <sequence length="249" mass="26104" checksum="FAAB39BA15E8DAE4" modified="2007-12-04" version="1">MMLEVSDITMRFGGLVAISDASLSVPKGGLVGLIGPNGAGKTTLFTIIAGFQMPTAGRVRFDGADITSQPAHVRAQHGIARTFQIVQPFAGLNVRENIAVGSYLRHPRRADAHAKAEAVAAQVGLAAELDKPAASLTVAGRKRLELARALATEPKLLLLDEVLAGLNPSEIRDIIPVIEGIRASGVTILMIEHVMQAVMSLCEQVYVLAQGRMIAHGPPREVCADAQVIEAYLGKGAAGRINGGEAAHA</sequence>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="165" mass="17029" checksum="E7414C85E3756D44" modified="2007-12-04" version="1">MDWSSLASEVIKLGAPVLGTALGGPLGGSVGKVLADTLGATADTPEAVAEAVATDPQAQEKLQALEAERSTEWVSVIQAGQALAAQLATTEATKGAFHYAWRPAMSWLVVAIVGQTFLLAPWISALIGKSVGTPYDQVLGISAVWLTIYGGGHTVKSIFGARLAR</sequence>
</entry>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAF88157"/>
        <property type="gene ID" value="AZC_2159"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2159"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="754" mass="82043" checksum="CE6B47CEBA9D45A8" modified="2007-12-04" version="1">MTRIVSFTEAEVAEPQDFGNISLYAREGDDHIVGGAIDYAHHWADFSISQPSSIELRINPGRLFAGAIVYAAEEPIDLNLQIHLPLVTGDRRYVALLLRGATRTLTAQRMIETDAETGETVEQAVPKTESRIVEVVIQQGLPSPTPLKPSVAADQCCLAFVELAPTGIVAVELDHGSRLKSLAEVEGRLTTLEGEVSNTIRRTTTLETDVANIASRLTDIPHPTIIRQLKRDVANVRRQLAMPDEARAYWYDAGLVQDAWDLTHATWLARVREGIRFPWAAERDSQLALLDPGSAALRMSGTLLLPAWEEAVRIEVPGDGGSTNISQLTHTVTTAVRREIARQVVEYGETVTVCENNAEWATSYGRSVGELFTVKGETFEVVAIAGNTEWAGHVLRAVRRIITRTVTDVYWDYVTESFGVNGSIYGQTWLCAQPMILTSIDLSFTRVGSSGDVHLFVCECDDTGQPRLDRVIVTTTLAAKDLAAGWVTFPLRPSLLESGRRYAWATVTTGNHALETVAGNRFAQGSRFTCTDGAWSQISTEVDFAMRIKAATFAAPRTVVEFAPLTLENGMTELRLLHGGWAPGGTALTWEVKPSTSNAWQPLTLADVEGGDTLAGLPALVQLRAVFVGTTDLQPAIVLDAKARGMTFRPRGEMIAVSRSQAFGLATSTIQLEVVVDAYDASRHNMQLRLVVGASILSPSAVSLTPDLVNPKKRTVLATFILGAPVTEARARVDMTTTTVTDVPFIQNIALYAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7X5</accession>
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        <submittedName>
            <fullName evidence="3">CoA binding domain</fullName>
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        <name evidence="3" type="ordered locus">AZC_2179</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF88177">
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        <property type="gene ID" value="AZC_2179"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2179"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88177.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="181" mass="19798" checksum="3AD44A2FEC5F336C" modified="2007-12-04" version="1">MRLDHDHYADAYIRGILDGVKTIAIVGASANAVRPSFFVTKYLAERGYRVFPVNPGQAGKEIAGLPAYARLADISEPVDMVDVFRASEHVPQVLDEVLALSPLPKVLWLQLGVRHAEVARKAEAAGLKVVMNRCPKIEYGRLSGEIGWTGVNSRTISAKRPKRLGQGVQRLSISRTSTPPE</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2221"/>
    <dbReference type="EnsemblBacteria" id="BAF88219">
        <property type="protein sequence ID" value="BAF88219"/>
        <property type="gene ID" value="AZC_2221"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2221"/>
    <dbReference type="eggNOG" id="ENOG502ZAVI">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029427_0_0_5"/>
    <dbReference type="OMA" id="GYLARWY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="474"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="505" mass="53677" checksum="B2B65BF4B014F2C8" modified="2007-12-04" version="1">MAEARKRRMSTSDRCLIPADMDCHAPVRVPMVRPGVPAFMTDALPAAPPLARVTPRVLAITAAGVVATLLLLAPALVNGFPFLFYDTGGYLDAAVNHLVKPGRSTVYGVLLVLGSRPDFWPVVVLQSALCVWALSLVMRVNGLGRRPLMLIALSALLTVATALPFVSGELMPDVFAGLTGLGLYLLLWRQEDLKRGEAVTLGVVIAFGGAAHSSVLAITLACVGAAAIGRALMPRRLPRPHLTLPLIAACGALVLTPVTNLALAGRFAATPGGTGFIFGRLLEDGLVHRYLADSCPQAGIEKLCAARMNLPATADDFLWDDDQTFNEIGGFEGGAAEMRQVIVGVLRSYPLENVTLALRAAARQMVALQTGDLMSEELTDSYDVIADLYPRSNAAMMAARQQQNPPIDFDRYSAVHVPVGLVATLLLAVVTVGAMVRGRRDIALLTGSALAFLIANAAVCGILSNPHDRYQSRIIWVAVAALFIAAMRIWDDRRGGRCAPCTSTA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8B0</accession>
    <name>PURL_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase subunit PurL</fullName>
            <shortName evidence="1">FGAM synthase</shortName>
            <ecNumber evidence="1">6.3.5.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Formylglycinamide ribonucleotide amidotransferase subunit II</fullName>
            <shortName evidence="1">FGAR amidotransferase II</shortName>
            <shortName evidence="1">FGAR-AT II</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glutamine amidotransferase PurL</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Phosphoribosylformylglycinamidine synthase subunit II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">purL</name>
        <name type="ordered locus">AZC_2231</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17129"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGAMS family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I8B0"/>
    <dbReference type="SMR" id="A8I8B0"/>
    <dbReference type="STRING" id="438753.AZC_2231"/>
    <dbReference type="EnsemblBacteria" id="BAF88229">
        <property type="protein sequence ID" value="BAF88229"/>
        <property type="gene ID" value="AZC_2231"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2231"/>
    <dbReference type="eggNOG" id="COG0046">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003100_0_1_5"/>
    <dbReference type="OMA" id="FIEPYQG"/>
    <dbReference type="OrthoDB" id="26038at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00420">
        <property type="entry name" value="PurL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010074">
        <property type="entry name" value="PRibForGlyAmidine_synth_PurL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43555">
        <property type="entry name" value="PTHR43555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001587">
        <property type="entry name" value="FGAM_synthase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01736">
        <property type="entry name" value="FGAM_synth_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000080546" description="Phosphoribosylformylglycinamidine synthase subunit PurL">
        <location>
            <begin position="1"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00420"/>
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    <sequence length="735" mass="78145" checksum="683DD1ECFB04DE0B" modified="2007-12-04" version="1">MIPNTPSITPELVAEHGLKPDEYQRFVELIGREPTITELGIVSAMWNEHCSYKSSKVWLRTLPTKGPRVIQGPGENAGVVDIGDGLAVVFKMESHNHPSFIEPYQGAGTGVGGILRDVFTMGARPIAALNALRFGDPHHPRTRRLLAGVVAGIGGYGNSFGVPTVGGSVGFHERYNGNILVNAMAVGLAKTDEIFYAAAAGVGRSIVYLGSKTGRDGIHGATMASAEFGADAEEKRPTVQVGDPFAEKLLLEACLEIMQAGCVVAIQDMGAAGLTCSAVEMGAKGDLGVELDLNAVPCRETGMTAYEMMLSESQERMLMVIADGKEDQAEAIFRKWGLDFAIIGKTTDTLRFVVKHDGDVKADLPIKELGDEAPEYYRPFTETPPRPVLGPSDVNHAVSVADALERLIASPDLCSKRWVWEQYDHLILGNTVQRPGGDAAVVRVNEGPKALALTTDVTPRYCEADPFEGGKQAVAEAWRNLTAVGATPIAVTDNLNFGNPEKPEIMGQFVGCVKGIGAACEALDFPVVSGNVSLYNETNGQGILPTPTIGGVGLIDDVEQSMTLAFKAAGEAIFVVGKTDGWLGSSAYLYTVCDREDGAPPPVDLVAEKRNGDFVRGLIKDDFITAAHDVSDGGLLVAIAEMAMAGRIGASVDGVPAGMPAHSFWFGEDQARYVVTLPANQAAEMVRRAEAAGVPVTKLGKTGGDKITLANERPIFVEGLRDRHDSWLPIYMGAN</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88745.1"/>
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    <sequence length="372" mass="39521" checksum="6F6B59844C2E2AFF" modified="2007-12-04" version="1">MHAVTCTGRRGEPCSMIRLSRRFLLTLVAASGLPRLGFAADPKLDPIPLIEGWLLPRYDTLREATEAQKAAWEAFVAKPDVGAIPGLKSAFAKAADAWTAVEFITLGPASQNLRPDRFNFFPDRRNAISRAMGEIISDADAGRVAPDRLAQSSAGAQGFPALERLLFEDGAADALLKGDEAVRRRAYGLGIAQNLATMAGEIRTAWGSRTEGVLGAIVSGKGDTTLFPDLGALPGMFLTDLAMAYQRTTDIKILPVLGPNPENAKPLLADGWRAGRSGQVVKVMITSANSLLQEVAKQLPSRPQYVVNRAATAADKAAADFPADLSAAAQTAAGEQKVQAEVKVFKAAQLTVYRPIASYFGISLGFNALDGD</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </evidence>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
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        <property type="protein sequence ID" value="BAF88826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_2828"/>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
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    </dbReference>
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        <property type="entry name" value="CHEMTRNSDUCR"/>
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    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
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    </dbReference>
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        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
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    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="213"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="10">
        <location>
            <begin position="241"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="8">
        <location>
            <begin position="335"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="9">
        <location>
            <begin position="487"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="348"/>
            <end position="369"/>
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    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="282"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="BAF88826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="591" mass="61863" checksum="73A64FB52BE09AD7" modified="2007-12-04" version="1">MSGLPVPLCWAGGNSRPHVPVMGDRMSFKNLSVMLKIGAIVLMLSACAGVGVALLSSQLHTVIGTYDAVIKNDEAAVLALVRYNRQVAVLQRALYQIAVASTPEQSAAADKELSDALAAMNNRLKEAKAASEQVGAIAQSFSARVDAAMASPCGPVIKFAREAMDPQSIVTAGQRMTNECDAALKPIGQEIVRANDRITAELNQRTDAVRDDALRLATLITTALAIAVLVCFGLGFAVARYGIVVPINRVLGVMSDIQAGKLQVKVPDTDRGDEVGTIAKSVETFRQGLEEAERLRQEAALQEQRSAEKVRNERLQIAANFEATMGNLARAFAQSSHEMSDAARSLAATAEETSRQAEAVGGAAEEASTNVNTVAASTEEMTASIREISAQVSQTATIATAAAAETSRTQTEIIELSQSAAKIGEVVDLITNIASQTNLLALNATIEAARAGESGKGFAVVAQEVKQLAAQTAKATEEIAGKVGEIQQATNRSVESIDRIVTTIGQIQTAASTVASAVEEQGAATAEIASNTQQAARGTETVNHNIAGVGRAAEMTGAASSQLMTLSQSITDQAQQLKREVEQVVANLRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9Z5</accession>
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        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
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    <gene>
        <name evidence="1" type="ordered locus">AZC_2443</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170969.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2443"/>
    <dbReference type="EnsemblBacteria" id="BAF88441">
        <property type="protein sequence ID" value="BAF88441"/>
        <property type="gene ID" value="AZC_2443"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2443"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_010194_1_2_5"/>
    <dbReference type="OMA" id="ENWDASY"/>
    <dbReference type="OrthoDB" id="1209997at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="259" mass="27328" checksum="B88A58D85CBE3BAE" modified="2007-12-04" version="1">MKLDLTNKTALITGASKGIGLAVAQVFAAEGCHLHLAARNGEAMAQAKSELEAAHGVRVTVHALDLSSTEAMEKLAEDVGYVDILINNAGDIPAGSLEIVDDAAWRRGFDLKVFGYITLARAFYKKMRGKDGVIVNVIGNSGENWDASYIAGSTGNAALMSFTKALGGASLNEGVRVVGVNPGPVATDRMLKIMKRKAIDMLGDESRWEELFDKYPGKRPATSEEVADLVAFLASPRAGYITGTNVTIDGGISARGSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA09</accession>
    <name>A8IA09_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2449</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2449"/>
    <dbReference type="EnsemblBacteria" id="BAF88447">
        <property type="protein sequence ID" value="BAF88447"/>
        <property type="gene ID" value="AZC_2449"/>
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    <dbReference type="KEGG" id="azc:AZC_2449"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="WAPRGNP"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="67"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="258" mass="27428" checksum="2E93FEC5065AC661" modified="2007-12-04" version="1">MSSAPEMVGTARPRSLTLQRGVLGIVLFVLAWEGIARGFHLPAYTLPAVSDILASIYAKRAVLLTAAGFTLTEALVGYVLGALIGIGLAIVITLIPPTRAVLLPAATAINSVPVVAYSPLILLWFGIGMGSKFVMVALAVSFTVFLSALAGFDRVDRRSVDLLRSFGAGRLAILWRLRLPTALPLIAAGLRVSTVRSLIVAIVTEMLGAYGGLGWVIYQAVLQIDFVQVWGAIFVASAASLAFFGLIGFAEKRIIFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA21</accession>
    <name>A8IA21_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Putative sigma-70 factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2453</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170979.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2453"/>
    <dbReference type="EnsemblBacteria" id="BAF88451">
        <property type="protein sequence ID" value="BAF88451"/>
        <property type="gene ID" value="AZC_2453"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2453"/>
    <dbReference type="eggNOG" id="COG4941">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035311_1_0_5"/>
    <dbReference type="OMA" id="RYEDTDW"/>
    <dbReference type="OrthoDB" id="1469807at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="2">
        <location>
            <begin position="109"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="413" mass="44992" checksum="91E5FB7D51A9E3DF" modified="2007-12-04" version="1">MDAAFRAASPAAMAALLRGLGTLDRAEDAFQEACLRALTHWPERGSPHDPTSWLVRVGRNAGIDRLRRHAREARLPTEHLVPATPDEEDRRADALDQTGLGDDVLRLLFICCHPDLAPAHQIALALRVVCGLSVPEIARVFLMGEAAMEQRITRAKRRVAQAGLPFETPAPRERQARLSAVSAMVYLIFTEGHSASAQESGRKAPLCMEAIRLGRLLATLFPEEPEVLGLLALMLLHEARAPARFSAEGSIILLEDQDRSLWNPVAIAEGTALTNRAFRMHRPGPYQLQAAIAALHARAPDVDRTDWAQIEQLYGVLADMEPTPVVILNHAVALSRAKGPAEGLARIVPLAQVLAGYFPYHAARGHLLERSGAREEAYAAYARSLDLAPSAAEAAQVRLYMDRLAAPTPVSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA64</accession>
    <name>A8IA64_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2469</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2469"/>
    <dbReference type="EnsemblBacteria" id="BAF88467">
        <property type="protein sequence ID" value="BAF88467"/>
        <property type="gene ID" value="AZC_2469"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2469"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_2_2_5"/>
    <dbReference type="OMA" id="HAMERGD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="56"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="246" mass="26054" checksum="0DDAE59EC44382E0" modified="2007-12-04" version="1">MIAMRHVLGPLLVILAGLVAWEALHLGVANSSLPSPLETLRQMGVLLGDPTFWKQAGQTFYAFAVAVVLSTAAGITLGVLLGMKRLAGEVAEPILVNLYSLPKVTLYPLVLLIFGLGISARIAFGIMHGLIPLTLFTMNAILQLKPVYRRSAAVMGLTSWQTAVSVILPAILPQVITGARLGVSLCLLGVLIGEMFASRNGLGYMVTHAMERGDMPTVLAVALLIAIVALVANGLLLALDRSRRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAG4</accession>
    <name>A8IAG4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitooligosaccharide deacetylase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2505</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2505"/>
    <dbReference type="EnsemblBacteria" id="BAF88503">
        <property type="protein sequence ID" value="BAF88503"/>
        <property type="gene ID" value="AZC_2505"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2505"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_0_2_5"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="312" mass="34275" checksum="1BE89393303EFFE7" modified="2007-12-04" version="1">MGRLHHLPLNASGSPARTVMANPRIPYRFSTSAPPLPPLNGKRILVHLVVNVEHWQFDRAMPRTIITPPHGQGSIPDVPNFSWADYGMRAGLPRILDLFRARGLPASTSFNAGVIDAYPQAAEAMLRAGWEFIGHGLHQKAIQNTDGDAEAEMIAAALDKIAGFTGARPRGWLSPGLRESERTPDLLKAQGVDYVCDWVVDDVPNWMTTAHGPLVAMPYNLEINDSIIYAIERHATGEMEKRLRHTLALFEAECTRSPRVLALGLHPHLISVPHRMHELVNMVDALAASPEVAFVTGSQICDWFTTAASPES</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <subcellularLocation>
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        </subcellularLocation>
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    <comment type="similarity">
        <text evidence="2">Belongs to the ATP12 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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    </evidence>
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</entry>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2521"/>
    <dbReference type="EnsemblBacteria" id="BAF88519">
        <property type="protein sequence ID" value="BAF88519"/>
        <property type="gene ID" value="AZC_2521"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2521"/>
    <dbReference type="eggNOG" id="ENOG5031A5J">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1127282_0_0_5"/>
    <dbReference type="OMA" id="PRQCKAR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="246" mass="25011" checksum="C6E402D85CDC24A3" modified="2007-12-04" version="1">MAGFARSRPSQGRCRPSIIGGAPMSPQTETCPGCGAPVHPDDVACAACGLELVSPAPSRRALPVVVGIAGVLVALAAGAGVWVLLTPKAPSSAASAPQQQAAVAPPPQAAPEPPPAPTPIPQTATPDPAPAAPAAAPTLQTVPPGSQRPPMPSIPSDPGTRRDYAKSTQDAFKENGLDMTVTATGEGATVMTLKFNFPAKTAVDLISGGPFPRQCKARGFKQVVFIDANGTTTWTLDLDTDKLTQK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAQ7</accession>
    <name>RS17_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsQ</name>
        <name type="ordered locus">AZC_2545</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171071.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAQ7"/>
    <dbReference type="SMR" id="A8IAQ7"/>
    <dbReference type="STRING" id="438753.AZC_2545"/>
    <dbReference type="EnsemblBacteria" id="BAF88543">
        <property type="protein sequence ID" value="BAF88543"/>
        <property type="gene ID" value="AZC_2545"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2545"/>
    <dbReference type="eggNOG" id="COG0186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073626_1_1_5"/>
    <dbReference type="OMA" id="HPMYGKF"/>
    <dbReference type="OrthoDB" id="2035880at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000073341" description="30S ribosomal protein S17">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <sequence length="82" mass="9669" checksum="F6E3E4E4CA16B419" modified="2007-12-04" version="1">MPKRVLQGVVVSDKQDKTVVVRVERRFTHPLLKKTVRRSKKYHAHDEANTWSIGDTVWIEEHRPLSKLKNWIVVQGEKRAEV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAT5</accession>
    <name>RS7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsG</name>
        <name type="ordered locus">AZC_2558</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171082.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAT5"/>
    <dbReference type="SMR" id="A8IAT5"/>
    <dbReference type="STRING" id="438753.AZC_2558"/>
    <dbReference type="EnsemblBacteria" id="BAF88556">
        <property type="protein sequence ID" value="BAF88556"/>
        <property type="gene ID" value="AZC_2558"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2558"/>
    <dbReference type="eggNOG" id="COG0049">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072226_1_1_5"/>
    <dbReference type="OMA" id="NVMPHVE"/>
    <dbReference type="OrthoDB" id="1540940at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000072403" description="30S ribosomal protein S7">
        <location>
            <begin position="1"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <sequence length="156" mass="17719" checksum="CCEDC1B2F6377ECB" modified="2007-12-04" version="1">MSRRHKAERREVIPDAKFGNIIVSRFMNSIMRDGKKSVAESIVYGALDVVEAKAKSNPLDLFVTALENVAPAVEVRSRRVGGATYQVPVEVRTERRQTLAIRWLIASARARNEKTMVERLSAELLDAANNRGNAVKKREDTHRMAEANRAFSHYRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB20</accession>
    <name>A8IB20_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ImcF-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">imcF</name>
        <name evidence="5" type="ordered locus">AZC_2597</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2597"/>
    <dbReference type="EnsemblBacteria" id="BAF88595">
        <property type="protein sequence ID" value="BAF88595"/>
        <property type="gene ID" value="AZC_2597"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2597"/>
    <dbReference type="eggNOG" id="COG3523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003353_2_1_5"/>
    <dbReference type="OMA" id="FFGYGGT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009612">
        <property type="entry name" value="IcmF-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025743">
        <property type="entry name" value="IcmF-related_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010623">
        <property type="entry name" value="IcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017731">
        <property type="entry name" value="TssM1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06761">
        <property type="entry name" value="IcmF-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14331">
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    </dbReference>
    <dbReference type="Pfam" id="PF06744">
        <property type="entry name" value="IcmF_C"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03348">
        <property type="entry name" value="VI_IcmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related_N" evidence="4">
        <location>
            <begin position="194"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF-related" evidence="3">
        <location>
            <begin position="504"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="IcmF_C" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1180" mass="128033" checksum="51D17B4CAC029BD5" modified="2007-12-04" version="1">MQMTLTTWTFWRWVLLFAAAAVFALLVWLLGPRLSFDGVSPFAGVTPRVMTTLIIVLLAGLVALYWALNQRHPATASETTKPSAPKKALPALEAPTASRAQREAMERGFQLALGVLKRIRTPGFFNRSYKYELPWYAIIGAEQAGKSALIRASGLRFPLNEARNGQINGGTISLSFTDQAVLIETRGPMVPPSEENTWGLFGLLLKRYRHRQPINGIVLVLSLSDMMRATDAERFSLHADLRDQLERFQATVKARVPIYVVFTKADIIPGFDEFCADLTSVERQGVFGVTLPLYDERGITTRGKPLPATFSAEFDNFLRWQMPRMASQVSQGFGVGPRFDCFMMLPHLATVKPLIADLIEDVFKPTTYDRPLLLRGFYFTSTQATSPRDANALPPAGTPDPAATRKTGLFIHDLFDKVIFKEAGLVEHDPTVRRNENVLRWGIATAGITLSLALLSWMTISFVANRYLIGEVERATDRTKTAIAALDANPTVQPSAETDFASVLPVLNSLAGLPTGWDARHQHVAWQLEGALGQKRYLAEATRQEYVEGLEALLTPRVIIALQREIAANMRNPDALYQALKVYLMLGHAGPMDRTVVVTWMHNLLANIYPGPTQAPLRNALLEHVENMLEVGVPPIELEQELISQARAVLNAYPAANQGMAILQNRSEIRALPVWRVTDVAGPLAPYALARRSGRPLNEPIDGMYTSAAFFPVVIPAISEVASSIISDDWVRFPSTPSAPEAARISQLTRDMTDLYVNDYISVWQNMVSDVTLAGFDNLQAELAVLQAALGPPSPLSSYLQAVTKETTIELPEAAGGAAKAVGTAAAAVAGPAAGAVNAVLQSGNARMKALAQSVTSRFSDLHTFASGTPSPLDEVLRSMSQLRALLGPAASMGGADPAQITEMTSGPQFAQILSQLKLNTLTAPPALTDSIVSLVRQTSTIANAGVKADLDSAWKTQVLPFCQAAINGKFPFSNSPNDVTLADFARMFAPDGLMDQFFNKQLKNFVDTLSSPWRPLTNVATHPDISPAGLAVFEQAAKIRAVFFPNGGTTPEVSFSITPTDLDPGAMRVKVEIDGQSFIYQYGPTVPTAMKWPGNVGSVRVEFGVGGDSGPAAVSYTGPFALFRFLAGRGVNRISPTRINFGVTLGPRSASFALDAASVNNPFQRPPYAGFRCPTSLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBJ4</accession>
    <name>A8IBJ4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="10" type="ordered locus">AZC_3079</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3079"/>
    <dbReference type="EnsemblBacteria" id="BAF89077">
        <property type="protein sequence ID" value="BAF89077"/>
        <property type="gene ID" value="AZC_3079"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3079"/>
    <dbReference type="eggNOG" id="COG2262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019597_1_0_5"/>
    <dbReference type="OMA" id="AEMKTGR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045498">
        <property type="entry name" value="HflX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19275">
        <property type="entry name" value="HflX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF89213">
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    <dbReference type="KEGG" id="azc:AZC_3215"/>
    <dbReference type="eggNOG" id="COG0381">
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    <dbReference type="HOGENOM" id="CLU_041674_1_0_5"/>
    <dbReference type="OMA" id="RYNTERP"/>
    <dbReference type="OrthoDB" id="1117971at2"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="22"/>
            <end position="367"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="388" mass="42412" checksum="26AF91F8821E8AC4" modified="2007-12-04" version="1">MKVMSIFGTRPEAIKMAPLVRAIEASADLSGLVCVTGQHRAMLDQVLSFFGIVPDIDLDVMVPNQTLNGLMSRVLARLDEALATHRPDYVLVHGDTTTALAATLAAFHRGIPVGHVEAGLRTYDLTQPWPEEMNRQVVDRMARDLFSPTEQSAAHLRDERAPGRIFVTGNTVIDALLMTLGRIDADAELKATLDRQFSFLDPGRRLVLVTGHRRENFGEGFAQICEALAALAQRQDIEIVYPVHLNPNVRGPVHERLSGKPNLHLIAPLDYVPFVALMRRANVILTDSGGVQEEAPSLGKPVLVMRDVTERPEAVAAGTVELVGTDAARIVAHVTRILDRADSPSASAARINPYGDGGASRRIVDVLCGRIPLPFHDRAAQRPARMRR</sequence>
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    <accession>A8ICP7</accession>
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            <fullName evidence="6">ABC-type cobalamin</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3237"/>
    <dbReference type="EnsemblBacteria" id="BAF89235">
        <property type="protein sequence ID" value="BAF89235"/>
        <property type="gene ID" value="AZC_3237"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG1120">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000604_1_11_5"/>
    <dbReference type="OMA" id="VEFGRYP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="24"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="56"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="277" mass="30170" checksum="C5399204AAC5CB79" modified="2007-12-04" version="1">MTLKFSSEFVSECTLPPDGDDPLFQLENAGFAVAGRDLVRAVSIRLAARRVVALIGHNGSGKSTLIKMLAGQLVPTSGRVCLAGRPVPEWSARAFARKVAYLPQQIPVADGMLVRELVSLGRYPWHGALGRFGTEDRRKVDEALVLTGMDGLCERQIETLSGGERQRAWIAMLIAQDAECLLLDEPTSALDIAHQIEVLGLVRTLARQRQLGVVVVLHDVNMASRFCDEIVAMKSGEMIVRGRPEDIMQPDLLKMIYGVDMTVVQHPGSGASVCIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDG2</accession>
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            <fullName evidence="2">CoxE protein</fullName>
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        <name evidence="2" type="primary">coxE</name>
        <name evidence="2" type="ordered locus">AZC_2934</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Lee KB."/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="7"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="235" mass="22788" checksum="39803EBB4EB2284C" modified="2007-12-04" version="1">MILALSFVAGLLTILNPCVLPLLPVVLAGAATSSRFGPLALALGLAASFAVSGVLLASAGIEFGESRALRFGAAGLLLVAGLALALPAVGEKLGALLAPLAGGAARLAGGLSPGLAGQFGAGALLGLAWAPCVGPTLGAAFALAASGGSKVQAAAAMGVFALGAATSLLLAGSGARLLAARGRGRLARAAHLSRRLFGVALVLVAVLILTGLDKTLEGIVVAALPDWFVSLATRF</sequence>
</entry>
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    <accession>A8IF07</accession>
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            <fullName evidence="1">DUF2019 domain-containing protein</fullName>
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        <name evidence="2" type="ordered locus">AZC_3560</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF89558">
        <property type="protein sequence ID" value="BAF89558"/>
        <property type="gene ID" value="AZC_3560"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3560"/>
    <dbReference type="eggNOG" id="ENOG5033ZRP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_165467_0_0_5"/>
    <dbReference type="OMA" id="AIAESKW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018568">
        <property type="entry name" value="DUF2019"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09450">
        <property type="entry name" value="DUF2019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2019" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="102" mass="11295" checksum="EC2022830C904C21" modified="2007-12-04" version="1">MSLEMKRADDWLEDAAYNRAYDELDKVMAELQVRPGDERQALLPLLAHPNIQVRLDAAIATLTLSAAATEAMQGIASLGYCSQAFSAKRMLRAIEEGTWKPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFR3</accession>
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        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
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    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="16" type="ordered locus">AZC_3642</name>
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    <organism evidence="16 17">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
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        </cofactor>
        <text evidence="13">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89640.1"/>
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    <dbReference type="KEGG" id="azc:AZC_3642"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="TOPRIM_DnaG_primases"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
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        <property type="entry name" value="DNA_primase_DnaG"/>
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        <property type="entry name" value="DNA_primase_core_N"/>
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        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="15">
        <location>
            <begin position="257"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="423"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAF89640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="643" mass="70716" checksum="7133B585C1B83A5C" modified="2007-12-04" version="1">MRFPPSFLDEIRTRLPVSEVVGRRVKLKKQGREFAGLSPFNAEKTPSFFVNDQKGFYHCFSSGKHGDVFDFLMETEGLPFGEAVERLASMAGLPLPDVTPEAAAKEARRRTLHEVMEMAAAFFEAELQARAGAKARGYLSDRGLGPSTQKRFRLGYAPGDRFALKEALGKAGVPVSDMVETGLLIAGDDIPVPYDRFRDRVMFPITDLKGRVVAFGGRALEKDVPAKYLNSPETPLFHKGSLLYNAYSARAAVQKGAPVIAVEGYVDVIALVEAGFEGAVAPLGTALTEEQLQLLWRMADEPVLLFDGDKAGRRAAFRAVGLALPHIKPGKSLSFGALPDGQDPDDLIRASGREAMEGVLAQAQPLSAMLWARETEGSNLETPERRAALEARIGEAVAAIQDENVRRHYKQDLQDRLRRLLSPGSENRPRRFEGGWSAAPGRSGNFRPQNGRFMREPPLVPGTELARSAVVRGPLASLPRNEALLLFCLINHPWLMDEYAEEVAGLPFANKDADRLRRALLEAHLEGAHEGEALTEHLTREDLDALAQRVRAFANPKMDWPAYPDTAPEDARLWWLQRAALHQKAYALSKELREAERSLGSDPSEANFAWLRDVRERLSAAEGTEALVEGFGASSGRGSHKSV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG13</accession>
    <name>TRMB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trmB</name>
        <name type="ordered locus">AZC_0015</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IG13"/>
    <dbReference type="SMR" id="A8IG13"/>
    <dbReference type="STRING" id="438753.AZC_0015"/>
    <dbReference type="PRIDE" id="A8IG13"/>
    <dbReference type="EnsemblBacteria" id="BAF86013">
        <property type="protein sequence ID" value="BAF86013"/>
        <property type="gene ID" value="AZC_0015"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0015"/>
    <dbReference type="eggNOG" id="COG0220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050910_0_3_5"/>
    <dbReference type="OMA" id="PDPWHKS"/>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000072995" description="tRNA (guanine-N(7)-)-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="209"/>
            <end position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <sequence length="230" mass="26108" checksum="D9F1B2D6A9D3F782" modified="2007-12-04" version="1">MTALSETEHKGAFYGRRVGKTLRQGQQQALARTLPRYLIDLPTVAEPAALFPCPVDEIRLEIGFGGGEHLLSEAKRFPRAGYIGIEPFLNGMAKAVLELDLAPQENVRLFNLDAALLLARLPEGSVSQVELLYPDPWPKRRHWKRRFVRPDNLDLLARALKPGGVFRFASDVPDYVDWTLREVRAHPAFRWTQTRADDWRTPYEGWPGTRYEAKAIAAGRVPTYLSFARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGJ3</accession>
    <name>A8IGJ3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA translocase FtsK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ftsK</name>
        <name evidence="15" type="ordered locus">AZC_0096</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer. Forms a ring that surrounds DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0096"/>
    <dbReference type="EnsemblBacteria" id="BAF86094">
        <property type="protein sequence ID" value="BAF86094"/>
        <property type="gene ID" value="AZC_0096"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0096"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001981_6_2_5"/>
    <dbReference type="OMA" id="IGPANHA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025199">
        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13491">
        <property type="entry name" value="FtsK_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="14">
        <location>
            <begin position="449"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="274"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="466"/>
            <end position="473"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAF86094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="814" mass="87214" checksum="6A414602864B7ACE" modified="2007-12-04" version="1">MPVRRRSASALTMRAHGGGMDFIPESVRLAIRRRSSEICGVVVLGAAAFALLSLMTWSASDPSLSNATNAKVSNLLGRPGAVLADLLMQLFGLASLAIILPLAIWGWRLLTFRPLKGEKLRIVALTFGALGTSAFLGALPAFGAWPMPTGLGGVMGDLIPRLFLLLTGSFGSFLESAVTGLLGGTLALAGLYVACRPNPPEDEAEEVDEPYDAEEVERGAMISLGALTHTFLSLKARLSGRRRSRTYVPSTPAARGPVVAGGRMEPRFAASAPAPVVPEAPVPDEETYVAPPPRSRSHGKRVPVAMPGRRGFYELPDLGLLAAPPPSKGPTMSAEALQDTAKLLESTLEDFGVRGEIVQVRPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAISARVAVVPGRNAIGIELPNQRRDKVLLRELLSTKDFSENGQKLAIALGKTIGGEPVIVDLARMPHLLVAGTTGSGKSVAINTMILSLLYRLPPDQCRLIMVDPKMLELSVYDGIPHLLAPVVTDPKKAVVALKWAVREMEDRYKKMSKLGVRNIDGFNARVADAQKRGESLARTVQTGFDHETGEAIYEREEMELGPLPYIVIIVDEMADLMLTAGKDIEGAIQRLAQMARAAGIHLVMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEMGAEQLLGQGDMLYMAGGGRISRVHGPFVSDEEVEHVVRHLKAQGAPDYVDAVTADFDEDGDEDGAVFDKSGMGEGGDIYSQAVAVVLRDKKCSTSYIQRRLQIGYNRAASLVERMEKEGLVGPANHAGKREILVTDEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGQ4</accession>
    <name>A8IGQ4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_0120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAE transporter (TC 2.A.81) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168651.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0120"/>
    <dbReference type="EnsemblBacteria" id="BAF86118">
        <property type="protein sequence ID" value="BAF86118"/>
        <property type="gene ID" value="AZC_0120"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0120"/>
    <dbReference type="eggNOG" id="COG2985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035023_2_2_5"/>
    <dbReference type="OMA" id="RDGKNYF"/>
    <dbReference type="OrthoDB" id="1458740at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022457">
        <property type="entry name" value="Asp_Ala_antiprt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006512">
        <property type="entry name" value="YidE_YbjL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06826">
        <property type="entry name" value="Asp-Al_Ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03802">
        <property type="entry name" value="Asp_Ala_antiprt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01625">
        <property type="entry name" value="YidE_YbjL_dupl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 11" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="411"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="474"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="533"/>
            <end position="555"/>
        </location>
    </feature>
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        <location>
            <begin position="16"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="9">
        <location>
            <begin position="304"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Asp-Al_Ex" evidence="10">
        <location>
            <begin position="387"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="558" mass="59144" checksum="1343353DFF63DE41" modified="2007-12-04" version="1">MSSVIATIQKYPEIAIYLTIAIGFWVGNLKIGNFSLGTVTSTLLAGLLIGQANISLPPVLQSTFFAMFLFAVGYAVGPQFVRALRSDGLPQVVFAVLVCISGLVTAVILGKLLGYNAALTAGLLSGGYTNSTVLGVATDLISQSGLDPQQLKMALSLMPVAYAVTYPFGTAGSAWILATLAPKMLKFDLAAECEAYEKAHGTGVGNGTTAYREFSARAFRVNNPELIGKSVREIERLFNHEIFVRRVRNGNRIVDCDDCTVIHENDVVAFSGSLSALIAYQDRFGVEVKDVPLLDFSTELLDLVVTNRAYANKTLGEILRTLFGKPGRGVFLTKFVRSDLAMPLNSEITIQRGDVLTILGAKEDVAKIAKELGYADRPLENSDMAFMGFGIVVGSLLGAITVHVAGIPLSFGTSVGAIVAGIFCGYLRSTKRTFGRIPGPALWVFNNVGLNGFIAVIGLNAAPGFVSGLQTYGVTLFLAGTVVTMVPLFVGLFLGHYVFKFNPAIMLGACAGARSTTAALGALQDAGRSKVPALGYTIGYAVSRLVMAVLTIVVVNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGT5</accession>
    <name>A8IGT5_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Peptide ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0132</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0132"/>
    <dbReference type="EnsemblBacteria" id="BAF86130">
        <property type="protein sequence ID" value="BAF86130"/>
        <property type="gene ID" value="AZC_0132"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0132"/>
    <dbReference type="eggNOG" id="COG4239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_0_5"/>
    <dbReference type="OMA" id="PSPPTWM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="183"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="385" mass="42814" checksum="DA195EFBAB2F7298" modified="2007-12-04" version="1">MSAMDTTANALPATDAPRKRPFFSPLNQRRITNFRHNRRGWWSFVLFMVLFVLSLFAEFIANNKPILIRYDGAYYAPVLRAYPETAFGGDFETEADYRDPYLQKLIAEKGGWMIWPPIHFSYSTHNLDLPTPAPSPPTWMLTEQQCAAVAEKKGVKGCAGLEYNWLGTDDQGRDVLARLIYGFRISVLFGLALTLISSVVGVAAGAVQGYFGGWVDLLFQRFIEIWTSIPSLYLLLIISSVLVPGFWVLLGILLLFSWVSLVGLVRAEFLRARNFEYVQAARALGVGNFTIMMRHLLPNAMVATLTFLPFILSSSVMTLTALDFLGFGLPPGSPSLGELLSQGKANIQAPWLGLTGFFTVAIMLSLLIFIGEAVRDAFDPRKTFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHR6</accession>
    <name>A8IHR6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Twin-arginine translocation pathway signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
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        <property type="protein sequence ID" value="BAF89310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF89310">
        <property type="protein sequence ID" value="BAF89310"/>
        <property type="gene ID" value="AZC_3312"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89310.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="498" mass="53803" checksum="4BF5B3F44E59941D" modified="2007-12-04" version="1">MIDRRTFIKAAGTAFVASRLATTAARAEANDPLSYASVDELVALFRARKASPVELLKAQIKRIEAFNSKINCITDEHFDQALKEARQSEDRYGRGDARPLEGITVAIKDEFSRPGWRVTQGSLVYKESPAMTENDAIIDALEAAGAVMPFQTTVPEFYLFIGASTRAWGTTHNPWNLAYSPGGSSAGSGAALAAGFATLAMGSDMGGSIRIPASQNGLYGFRPPFGRVASGEVPFSTSGPLARRCDDLLHLQNAIVGPSDRVMAAIRPRLDYPAQYPDLSGWRIAVDWGAAVAEVIPSVKAAMQDGVDTLRKAGCVVDEVDCGFSKDQKLVFIRGLMATSLGTLVDVANANRGLLSPYMAEVIDLVGAVGPRQAEEAEALAERLHRQVQQRVFGKGYRVLLMPTMATPLVRADMFKSKADNVDLWTGTGFGAALTWPWNLLNRYPVVDVPLGLVDEGMPSGMQVIGQTFADLDTFQFASTWARLRPALFADGRFPTFV</sequence>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF89424">
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        <property type="gene ID" value="AZC_3426"/>
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    <dbReference type="KEGG" id="azc:AZC_3426"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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        <source>
            <dbReference type="EMBL" id="BAF89424.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="223" mass="24237" checksum="075E3DD9DAE5F70E" modified="2007-12-04" version="1">MAMMKFYMTPGSCSTGIHILLEELEQVFEAHVVNLPAGDHFRPEYVAINAKSTIPTLVRRDGTALTEVPAIAYWLGRTHPRAGLWPQDVEVETRLLEAMAYMTATIHGQGFARLFATSTFTRNAADHPAVKALGEEIVRKGFGVLAQALGEGPYLAGGFSVADPILFYLEFWADKLGLALPSAVAAHYARMLDRPVVRRVLAEEGYAPSKLGQVAIADAVEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ11</accession>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="4" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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        <property type="protein sequence ID" value="BAF86244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_0246"/>
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            <end position="86"/>
        </location>
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    <sequence length="343" mass="37158" checksum="CFD0EF5444624C6A" modified="2007-12-04" version="1">MPFPSGAGLWFLRRVWCGGMRVAEPFKNLAWDDFRLIKAVADARSLPAAAVQMGVNHSTVFRRLKQIEEALGVALFVRHRTGYALTPAGEEVVALAERVDADITSVTRKIAGRELAPAGELRVTTNDSLLVHLLMPMLARFREACPSVRLDVVLGNQALNLSKRDADVAIRASDTPPDNLVGRRVARIGWALYGLARRFPSADAIAQMDPAAEDWVSLGDGFGGMKVVKDTLARIPPERIAYRVNTVFGLAEAIEAGLGIGYAPCFIADPRPALVRLAPPEPAYAADLWLLTHPDLRHAARVRVFLDFMAGEIARYRVFLEGAAEGGDAVAEQALASEEAGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILL1</accession>
    <name>A8ILL1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma-glutamyltranspeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172569.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4049"/>
    <dbReference type="MEROPS" id="T03.025"/>
    <dbReference type="EnsemblBacteria" id="BAF90047">
        <property type="protein sequence ID" value="BAF90047"/>
        <property type="gene ID" value="AZC_4049"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4049"/>
    <dbReference type="eggNOG" id="COG0405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014813_3_0_5"/>
    <dbReference type="OMA" id="FWPLGHL"/>
    <dbReference type="OrthoDB" id="803717at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="531" mass="57036" checksum="B0274FA83EFC3447" modified="2007-12-04" version="1">MSHESTHTARGIVAAPHALAVEAGRQVLAEGGNAVEAALATAAAIAVVYPHMNHLGGDGFWLIREPNGRVRYIEACGFAGARATIKSYRDAGYDTIPERGPLAALTVPGLVGGWGLALEAARAAGGRLPLPRLLESAVQHARAGVAVTRSQAQLTADKLAELKDAPGFSAQFLVDGKPPEVGHIQKAERLADTLEHLGRAGLEDYYRGDVAHEMAADLERIGSPVTRADLERYRAVVREPLSVDLPEGRIFNAPPPTQGLASLLILGLYSRLGVKRAESFDFIHGLVEATKRAFLVRNEVVRDFEHLKHDPAHFLTPAALDADAARIDRRRALPWPQPAKRGDTIWLGAADASGLVVSYIQSIFFEFGSGCVLPHTGILMQNRGASFSLDERAVNPLTPGRRPFHTLNPALAVLRDGRVMAYGTMGGEGQPQTQAAVFSRHVLHGVPLGEAIERPRWLLGRTWGSTHTNLRLENRFDEDVVRALVSAGHDLEVLPEAFSDTMGHAGAVIYTPKRDLEGAHDPRADGGAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILX1</accession>
    <name>A8ILX1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M3B protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_0437</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0437"/>
    <dbReference type="MEROPS" id="M03.007"/>
    <dbReference type="EnsemblBacteria" id="BAF86435">
        <property type="protein sequence ID" value="BAF86435"/>
        <property type="gene ID" value="AZC_0437"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0437"/>
    <dbReference type="eggNOG" id="COG1164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021290_3_0_5"/>
    <dbReference type="OMA" id="YRQTMFA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011977">
        <property type="entry name" value="Pept_M3B_clade3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02290">
        <property type="entry name" value="M3_fam_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="155"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="238"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="634" mass="70521" checksum="4C863200D2A04EBF" modified="2007-12-04" version="1">MALKAGAVARYDRHSRFDASGGAMFGPVSFLTPDAATASAPATPLPEWNLADLYAGMDDPRIATDLAEADALSKAFEADYKGKLADIAAAADAGAQLGAAVKRYEAIDDLMGRVASFGSLVYAGDTADPARAKFFSDIQEKLTDSSTHLLFFTLEMNRLEDAQVEAALKDAAFGHYRPWVEDLRKDKPYQLEDRVEQLFHEKSSPARGAWGRLFDETMSSLRFSVDGKELAIEPTLNLMQDPNEAVRKAAGQALAQTFSENLRLFSLITNTLAKDKEISDRWRGFEDVADSRHLANRVEREVVDAMVASIREAFPRLSHRYYALKAKWFGKEKLEFWDRNAPLPKVDTRDIGWDEARDTVLGAYSTFSPRMADIARVFFDKNWIDAPVRPGKSPGAFAHPTVPSAHPYVLLNYQGKPRDVMTLAHELGHGVHQVLAGRQGALMAPTPLTLAETASVFGEMLTFRRLLAAAETPQARKIMLAQKVEDMINTVVRQTAFYTFERKVHTERRQGEITAERIGELWMDVQTESLGPAINLSAGYETFWTYIPHFIHSPFYVYAYAFGDCLVNSLYAVYQKASDGFAERYLEMLAAGGTKHHSELLAPFGLDARDPAFWQTGLGLIESMITELEQMEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM31</accession>
    <name>A8IM31_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gntR</name>
        <name evidence="5" type="ordered locus">AZC_0475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169006.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0475"/>
    <dbReference type="EnsemblBacteria" id="BAF86473">
        <property type="protein sequence ID" value="BAF86473"/>
        <property type="gene ID" value="AZC_0475"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0475"/>
    <dbReference type="eggNOG" id="COG1802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_5_2_5"/>
    <dbReference type="OMA" id="EYERFFF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="18"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="225" mass="24982" checksum="8C323A80603E5DC8" modified="2007-12-04" version="1">MLERGASFRSLEAEAAPRSLREEAYDIIKQRIIRGLYRPGEALSEAVVSSSLSLGRTPVRQAFDRLMRDGLVEVLPRKGIIVRPITADEIRDMVHVRLLNEGFCARLAAERADQAVLGVLNDTLDQSHKAARDSDIETLMVLDRRFHAALASAAGNAVLSDILSNLHDRSQRVWFLSLREHQHHARVVEEHAGIVAAISARDAEGAEAVMRAHILSFAENLSRQL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM57</accession>
    <name>RL31_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmE</name>
        <name type="ordered locus">AZC_0493</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169024.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IM57"/>
    <dbReference type="STRING" id="438753.AZC_0493"/>
    <dbReference type="EnsemblBacteria" id="BAF86491">
        <property type="protein sequence ID" value="BAF86491"/>
        <property type="gene ID" value="AZC_0493"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0493"/>
    <dbReference type="eggNOG" id="COG0254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114306_3_2_5"/>
    <dbReference type="OMA" id="YHEITVV"/>
    <dbReference type="OrthoDB" id="2014569at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00501">
        <property type="entry name" value="Ribosomal_L31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027491">
        <property type="entry name" value="Ribosomal_L31_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000126562" description="50S ribosomal protein L31">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00501"/>
        </source>
    </evidence>
    <sequence length="74" mass="8282" checksum="70FC2566BFBD3BB8" modified="2007-12-04" version="1">MKSDIHPDYHFIKVVMTDGTEYTTRSTFGKEGDTLALDIDPRTHPAWTGGTQQLLDRGGRVSRFKNKFGALLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM87</accession>
    <name>A8IM87_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0508</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0508"/>
    <dbReference type="EnsemblBacteria" id="BAF86506">
        <property type="protein sequence ID" value="BAF86506"/>
        <property type="gene ID" value="AZC_0508"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0508"/>
    <dbReference type="eggNOG" id="COG0212">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066245_0_1_5"/>
    <dbReference type="OMA" id="GIVFDFA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="140"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="207" mass="22219" checksum="51E42EF503C3153D" modified="2007-12-04" version="1">MTLSSPTTFRSEKARLRAEALLRRADMGAERRAAASDAAARHALMALGSVAGRTVALFAPFRDEIDTGPLARKLRDAGARLALPVVIGRDRPLIFRLWDENDLLEPAGAYGIPTPGAQAPQVTPDDLMVPLAVFDRAGARIGYGAGFYDRTLALLRREKPIRAFGLAFACQETDHVPAEPHDEPLDGMVTEAGVLFLGGSDADSLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMU4</accession>
    <name>A8IMU4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrogenase expression/formation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hypC</name>
        <name evidence="2" type="ordered locus">AZC_0610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HupF/HypC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169141.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0610"/>
    <dbReference type="EnsemblBacteria" id="BAF86608">
        <property type="protein sequence ID" value="BAF86608"/>
        <property type="gene ID" value="AZC_0610"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0610"/>
    <dbReference type="eggNOG" id="COG0298">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_159381_1_1_5"/>
    <dbReference type="OMA" id="HYPARVD"/>
    <dbReference type="OrthoDB" id="2031925at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019812">
        <property type="entry name" value="Hydgase_assmbl_chp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001109">
        <property type="entry name" value="Hydrogenase_HupF/HypC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35177">
        <property type="entry name" value="PTHR35177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01455">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    </reference>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="AZC_3799"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <proteinExistence type="predicted"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="152"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF89797.1"/>
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    </evidence>
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    </evidence>
    <sequence length="167" mass="16702" checksum="0D4BFED7180C899B" modified="2007-12-04" version="1">MPPLVAAMVSLGVLGAIDTYLTATIFPVPVWVTFVAWASFFACGGGRHGLVKSVASNWVGILIASLTLLVIETGPVNSAFAAILVGLGTSVMILVSAERVLDFPPAIVLGFASLVGTGAATGATIAGAAGFSHPTLVAMAAMLAGALFGLVSERGTQMLTTKTPASA</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6" key="5">
        <citation type="submission" date="2009-01" db="EMBL/GenBank/DDBJ databases">
            <title>Azorhizobium caulinodans ORS 571 seed-exudate induced efflux genes.</title>
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                <person name="Cai W."/>
                <person name="Zhu J."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="7">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
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        <location>
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            <end position="105"/>
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        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89805.2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="429" mass="46845" checksum="E0890EC20E1CCE5D" modified="2008-05-20" version="2">MRTYGLERWGLTLVSTLILAIGIGRVAWGVMFQERIEFSDGSGWDGVHYERLFNYFGGGAIGHSTAAFPYCARLAIPWILSLISNHVSSFYFCNIAVSILLSILSCRFACEIFGVDLRVVASTMFLSSFCYFSPLRFSSFYPIYVDPPFMLLMLLSMYFVVMARFTCAILVCIVAIPVKEAAFYVIPIVILYDVMVKAPSRKKSGLYCVLICGAVGIKVIVPYMLGCSGEVQLVTGAYWLLRALSDPEHFLSAVASVSLTAGPLWLISGSASLCSGRDHVLAFSRLAIVWAVVLAVCGGSDVARIFYGFSPLYAPLIIRALRYAGKIEYLCACVGWVLTNRVLQSYWQPGYRNEGGYLTGFFSQFPDYAGPSVALQTIGVWLVLGCICRGAARLRASMDMSSAAHEGVLTDSSGWMPRGSAKAAKEGGV</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FliE family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169166.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0635"/>
    <dbReference type="EnsemblBacteria" id="BAF86633">
        <property type="protein sequence ID" value="BAF86633"/>
        <property type="gene ID" value="AZC_0635"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0635"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0969">Cilium</keyword>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="109" mass="11363" checksum="B666D0BC8917DFA1" modified="2007-12-04" version="1">MIETVSALSSSLRTPTSISSTKMETTETKLTALNGQQGADFGDVLASVTTDAMKTVRQGEAAGIAAIQGKASIQQVVEAVMSAEQTLQTAIAVRDKVVAAYQEVSRMAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPM6</accession>
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            <fullName evidence="3 9">Flagellar biosynthetic protein FliQ</fullName>
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        <name evidence="10" type="ordered locus">AZC_0653</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF86651">
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    <dbReference type="KEGG" id="azc:AZC_0653"/>
    <dbReference type="eggNOG" id="COG1987">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_164516_0_1_5"/>
    <dbReference type="OMA" id="MVQAATS"/>
    <dbReference type="OrthoDB" id="1939288at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006305">
        <property type="entry name" value="FliQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01402">
        <property type="entry name" value="fliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="88" mass="9257" checksum="E72DFA141C8E9F57" modified="2007-12-04" version="1">MNEADALDVVRNAIWTILLAAGPAVAAAMLVGIFIALIQALTQIQEATLTFVPKIIAVLVVCALTGSFMGSQIMAFTEEIYGRIASGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPX3</accession>
    <name>A8IPX3_AZOC5</name>
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        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
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        <name evidence="6" type="ordered locus">AZC_0711</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169242.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0711"/>
    <dbReference type="EnsemblBacteria" id="BAF86709">
        <property type="protein sequence ID" value="BAF86709"/>
        <property type="gene ID" value="AZC_0711"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0711"/>
    <dbReference type="eggNOG" id="COG0802">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3178">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021467_2_1_5"/>
    <dbReference type="OMA" id="SPNIIWR"/>
    <dbReference type="OrthoDB" id="443861at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012180">
        <property type="entry name" value="Bifunc_ATPase/PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036599">
        <property type="entry name" value="AtpPhos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="APH" evidence="5">
        <location>
            <begin position="183"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="517" mass="57688" checksum="8804A2EEA983F9E0" modified="2007-12-04" version="1">MSLSFERVPGRPATLAVELRTLADTAQLAATLTPWLSNGDVVALSGDLGAGKTALARFLVRALAGDPRLEVPSPTFSLVITYEFGRGKVTHADLYRLADPEELDEIGWDEMCEDGILIVEWPDRAGSHMPASRLDVALELAPDLGPDARRALLVGSGAFAERLDRLNVAEYLIESSGFGKAERRYLQGDASSRSYARLVLPDRSAVLMNAPRRPDGPPVKRGLPYSRLVHLAEDVRPFIAMAKALRHEGFSAPEIYAADLDRGLLILEDLGSDGVVAGNPPEPIRERYAASMELLANLHSRPLPSVLHIAPQVEYVLPTYTIEAFLIEVELMLDWYLPFRGAQADQLVRDEFLLLWRGALSTVLHEPQTWVLRDYHSPNLIWMDHRRGLGKVGLIDFQDAVLGPAAYDVASLAQDARVDVPETLEVDLLDHYIDIRQEAEPTFDATRFEHLYALMGAQRATKILGIFARLNARDGKPQYLRHLPRIRRYLARCLSHPELGSLRMWYEAVLPSREFQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQL0</accession>
    <name>A8IQL0_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0795</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1127"/>
    <dbReference type="EnsemblBacteria" id="BAF87125">
        <property type="protein sequence ID" value="BAF87125"/>
        <property type="gene ID" value="AZC_1127"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1127"/>
    <dbReference type="eggNOG" id="COG3391">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_007148_0_0_5"/>
    <dbReference type="OMA" id="RITCDPA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025195">
        <property type="entry name" value="GTA_TIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032876">
        <property type="entry name" value="J_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13547">
        <property type="entry name" value="GTA_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13550">
        <property type="entry name" value="Phage-tail_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTA_TIM" evidence="2">
        <location>
            <begin position="437"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="Phage-tail_3" evidence="3">
        <location>
            <begin position="795"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1172"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1272"/>
            <end position="1299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1299" mass="138741" checksum="7E09711DC44198A5" modified="2007-12-04" version="1">MATLLLGAAGSAVGSLFGPIGALAGRALGALGGAALDQMLLSGGGSSRTVVGPRLSSLDVMTSAAGASLPRIYGRVRVGGQVIWATQLEEVASASTPRSGGKSAVSGSRTTTVSYSYFGSFAVGLCEGPVTRIGRIWADGKPLDLTGVTVRCYTGSEAQSPDPWIEAKQGAGNTPAYRGLAYVVFERLPLARYGNRLPQITVEVERAIGQLEQQVRAVTLIPGATEFGYQPDLVQRVTGYAAYAPENRHTVSAPTDLAAALDQLQAQCPNVKRVSLVVTWVGSDLRAGVCRIEPKVERQDKETLGAQWRVAGLSRAEVATVSWYGGSAAYGGTPSDSSVMGAIAALKARGLEVALNPFIMMDIPAGNGLPDPWTLGPDQAPYPWRGRITCDPAPERPGSPDGSAQAEAQIDALFGSARAEHFLRFGTDLFYIGPLEWSLRRMVLHYAHLAVMAGGVETLLIGSEMAALTRVRGPGGSFPAAERFARLAADVKGIVGAGTNVSYGANWDEYGGQAFADGTLAFPLDILWGSPAVDFVGIDYYAPLADWRDGADHLDAARAVTLYDRAYLKANLRGGESYDWFYADEAARAAQVRTPITDGAYGEPWVFRQKDLWSWWANAHHARPGGVRDGAPTAWVPGAKPIRLMEMGCGAVDKGPNRPSTFPDAKSSEGGFPPFSNRGRDDFIQRRTLEMMTAAFDPAFGASDADNPPACVPGGRMVDPGIYLWTWDARPFPYFPLATSVWADGENWETGHWLPGRLGTAPLDALVARICADHGLSDVDASALEGVVDGYVVSDPTTARAAIEPLARAFAFDAVEEGATLVFRPRGRRVVTSLDEDDLVAQEDAAPLLLTRAQETELPLEVEIAFGDGGADYRRRTVSSRRLAGAARHVTRLEVPAMASDALMVRAADMLLQDTWAGREEARFTLPPSLRALQPGDVVDLTCDGRTRRLEIREISDGEGRAVTARTVDLSVFRSALRRASAPPVPVARASGPPGVLLLDLPPLDAGDPPVLQYLAATATPWPGALTVWRSSDGASFTTLASVTTPATVLSLLDPLPPGPLWRFDRSTRVRVELLAGALVGRSEAEVLEKANALALVAEGRASEVLHSHRRSCWGRAFMNSPACSVGRLAPRLRWRRAGPPVRGPCCWMRLWCRSLRTSRRSAAACSIASAGPTGTMATRRCSKSPPPYRTPRSDPMRRCILPGRAPRRASRSPGSAGRASTAMAGPASKCHSGKGPSATAWRSSPAKRCCGQSKRRRRPFSIRLPTNCWISARRRPGSPCASPSSPHSSAPVARRLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRG4</accession>
    <name>A8HRG4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline dehydrogenase</fullName>
            <ecNumber evidence="7">1.1.99.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1183</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>A + choline = AH2 + betaine aldehyde</text>
            <dbReference type="Rhea" id="RHEA:17433"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15710"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.1.99.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.99.1" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1183"/>
    <dbReference type="EnsemblBacteria" id="BAF87181">
        <property type="protein sequence ID" value="BAF87181"/>
        <property type="gene ID" value="AZC_1183"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1183"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002865_7_1_5"/>
    <dbReference type="OMA" id="NHFESCA"/>
    <dbReference type="UniPathway" id="UPA00529">
        <property type="reaction ID" value="UER00385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008812">
        <property type="term" value="F:choline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019285">
        <property type="term" value="P:glycine betaine biosynthetic process from choline"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011533">
        <property type="entry name" value="BetA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012132">
        <property type="entry name" value="GMC_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11552">
        <property type="entry name" value="PTHR11552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000137">
        <property type="entry name" value="Alcohol_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01810">
        <property type="entry name" value="betA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00623">
        <property type="entry name" value="GMC_OXRED_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00624">
        <property type="entry name" value="GMC_OXRED_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0274">FAD</keyword>
    <keyword evidence="2 6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="8">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="9">
        <location>
            <begin position="264"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000137-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="562" mass="61378" checksum="59F8ABEFB370E002" modified="2007-12-04" version="1">MMERTVASPASPAIFDYVIVGSGSAGAVLADRLSADGRFTVHVLEYGGSDRSLLIQMPAALSIPMNMPKYNWGFETEPEPGLGGRRLVCPRGKVIGGSSSVNGMVYVRGNPHDFDRWEEEGAQGWGYRHVLPYFQRAESRQEGGDAYRGATGPLATRYGPLENPLYNVFVEAARQAGYPATSDINGAQQEGFGRMDMTVKDGVRWSTANAYLKPALKRPNLSLETHALVLAVELEGRRAVGVRYERDGTEQIVKASREVILAAGPINSPKLLKLSGIGPAQELADLGIPVVADRPGVGENLQDHLEFYFQVACTQPITLYSKTGLLSRGLVGAQWLLARSGLGASNHFESCGFIRSRAGIRYPDIQYHFLPLAVSYDGKGLASEHGFQAHVGPMRSKSRGWVRLRSRDAREHPRIFFNYLGHEDDITEMRACVRLTREIFAQAAFDPYRGREIQPGADVTSDEAIDAFVREKVESAYHPSCSCRMGRADDPMAVVTPDTKVIGIEGLRVVDSSIMPSVTTGNLNAPTIMIGEKASDIILGKPALAASNAPYYTAENWRTAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRN9</accession>
    <name>A8HRN9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4071"/>
    <dbReference type="EnsemblBacteria" id="BAF90069">
        <property type="protein sequence ID" value="BAF90069"/>
        <property type="gene ID" value="AZC_4071"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4071"/>
    <dbReference type="eggNOG" id="COG3878">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056726_1_0_5"/>
    <dbReference type="OMA" id="FVAQINF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015315">
        <property type="entry name" value="DUF1963"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035948">
        <property type="entry name" value="YwqG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09234">
        <property type="entry name" value="DUF1963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103032">
        <property type="entry name" value="SSF103032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="367" mass="40768" checksum="F68E12EEC83F0220" modified="2007-12-04" version="1">MCAERQEKRQEPLRNMSKALPRTRDALRASLGDEDLPAEIVERLAAQALPALLLTTAALGENRPLPGASRLGGTPDLPPGMGWPMRPPYPDAERRAAGHRKDARRLLEDSRKPRSWMTPEQGVMFSQERMAKADATERPFPLAFFGQFDLAALSAIEGFDPLLPNTGRLLVFYDFWEQPEDFTPEAAVGWRVIWDDSPRDLLTPAAVPMDLETISSDDWTTIFAPALISAVPVVTPIPMSERGWDAFDLKDEDLREVYGDWLSQFGTPDEDGGENHQLGGFPRPLQNGLQATSQLASHGIYCGNGDAWKTPEAQALLKEAGAWRLLLQVGVDLNAGMRGPGAYYVIIRNEDLAARRFERARVTYQCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS32</accession>
    <name>A8HS32_AZOC5</name>
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4133</name>
    </gene>
    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4133"/>
    <dbReference type="MEROPS" id="S41.004"/>
    <dbReference type="EnsemblBacteria" id="BAF90131">
        <property type="protein sequence ID" value="BAF90131"/>
        <property type="gene ID" value="AZC_4133"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4133"/>
    <dbReference type="eggNOG" id="COG0793">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017295_1_1_5"/>
    <dbReference type="OMA" id="TFNQVDW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720664" evidence="5">
        <location>
            <begin position="21"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="90"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="380"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="448" mass="47795" checksum="EEC6BF4240C8DC7C" modified="2007-12-04" version="1">MRRTSLFLLGVAAGALVAVAAVQPRLFLGTAAEAAASDTYRQLSLFGDVFERVRSDYVEKPDDAKLIEAAINGMLTSLDPHSSYMDAKSFRDMQVQTRGEFGGLGIEVTMEDGLVKVIAPIDDTPAAKAGVQAGDIITKLDGDQVQGLTLNQAVEKMRGAVNTPITLTIVRKGAEKPIEIKVVRDTIKVKAVRARVEDGNIGYLRITSFNEQTYDNLKKGIEDVTAQIGPDKVKGYIIDLRNNPGGLLDQAIAVSDAFLERGEIVSTRGRNADETQRFSARGGDLVKGKPIIVLVNGGSASASEIVAGALQDHKRATILGSRSFGKGSVQTIIPLGGNGALRLTTARYYTPSGRSIQAKGIEPDIVLIQDMPAEQKAKLEAVGADTTRGEASLKGHLKNGDDEQTGSPSYVPPDPKDDTQLKMAKELIEGTQKNAAFPPNPNKTSQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS60</accession>
    <name>A8HS60_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="12" type="ordered locus">AZC_4144</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172664.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4144"/>
    <dbReference type="EnsemblBacteria" id="BAF90142">
        <property type="protein sequence ID" value="BAF90142"/>
        <property type="gene ID" value="AZC_4144"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4144"/>
    <dbReference type="eggNOG" id="COG1198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013353_4_0_5"/>
    <dbReference type="OMA" id="RCHYCGY"/>
    <dbReference type="OrthoDB" id="1132322at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="206"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="403"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="433"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="460"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF90142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="724" mass="78238" checksum="4887D35E3992E7B1" modified="2007-12-04" version="1">MTAATVDVLLPLGLDVPYSYLVPDGLELAPGDLVAVPLGSRLVVGCVWPRGAEAPAPVDTSKLKAVRKKLDHRPLPPDLLQLIDWMADYTLAPRGMVLRMALRHEENPSPARERVGVRATGHVPERLTAARKRLIEVMADGFVRAKTDAAREAGVSPSVVDGLVDEGALETLVLPPAPAAETPDPDHAAPTLSEPQAQAANAIIAAVQAKAFSVHLLDGVTGSGKTEVYFEAVAEAVREGRQALILLPEIALTQAFIDRFTRRFGVAPAEWHSGVSTRRRGRILRGVADGDVQVVAGARSALFLPFQDLALTIVDEEHDPAYKQEDGVTYHARDMAVVRSRFCRSPIVLTSATPSIETEVNARRGRYNRLSLPLRFGGAKVPGLSPIDLRKDMPPRGRWIAPRLQSEIAQTLEDGGQALLFLNRRGYAPLTLCRSCGHRMRCPSCSAWLVEHRFRRRLSCHHCGYQAPVPECCPACGAKDAMIPCGPGVERLQEEVQALFPEARSLVLSSDIGGIERMRAELEAVANGEVDVVVGTQLVAKGHNFPGLALVGVVDADVGLGHGDPRAAERTFQLVHQVAGRAGRGATEGRGFIQTHMPDHPVMQALVKGDRAAFYETEIAAREEAHLPPFGRMASLIVSANEGPAAEAHARRLAASAPRVEGVRVLGPAEAPLAVLRGRHRWRLLVRAPRAFDLSAYLRGWRSVAPRPTGNTKVSIDVDPMTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS78</accession>
    <name>A8HS78_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">MaoC-like dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">maoC</name>
        <name evidence="2" type="ordered locus">AZC_4151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4151"/>
    <dbReference type="EnsemblBacteria" id="BAF90149">
        <property type="protein sequence ID" value="BAF90149"/>
        <property type="gene ID" value="AZC_4151"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4151"/>
    <dbReference type="eggNOG" id="COG2030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094876_1_0_5"/>
    <dbReference type="OMA" id="VNEVRWL"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="35"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="171" mass="18704" checksum="BCA64E078BAA935B" modified="2007-12-04" version="1">MTFCPAASEIAGKLEEGMPDIYWEDFVQGDVKTFGSHEVTAEEITSFAREFDPQPMHLDPAAGAASMLGGLAASGWHSCAIIMRLICDGFLLRSAGMGSPGVQETKWLEPVRPGDVLTLRRTVLESRSSKSRPDMGLVTFRFELLKDKKTVAVDQTVVIMFARRNPGARLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSV1</accession>
    <name>A8HSV1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4220"/>
    <dbReference type="EnsemblBacteria" id="BAF90218">
        <property type="protein sequence ID" value="BAF90218"/>
        <property type="gene ID" value="AZC_4220"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4220"/>
    <dbReference type="eggNOG" id="ENOG50337PE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1118383_0_0_5"/>
    <dbReference type="OMA" id="QHMARTT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="248" mass="25510" checksum="458649A19ACF2B46" modified="2007-12-04" version="1">MEKTLHRAGLFIVTGYRHRKALTGIAGPMTRIATVLTVLFALITAACVAFGAYFSYVTLLSANRAAVEERFTVTAARVATTAELANSLGIAVASQHTLEELVAREAGLDAAVRSIDVADEHGQIVFSSDAARQGTTLPPRAAAMVSRRIENDIGAAIGRVAVSYDPAVLQRDAAQLAADIRVFAVPAVLLAALATGLAGLLIAGNVGRALRNAGNPAQWPASAQAALGRLDRAHAAALVGAPAAGEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT34</accession>
    <name>A8HT34_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Permeases</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
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                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <source>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1002"/>
    <dbReference type="EnsemblBacteria" id="BAF87000">
        <property type="protein sequence ID" value="BAF87000"/>
        <property type="gene ID" value="AZC_1002"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1002"/>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027070_1_4_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase_S11" evidence="10">
        <location>
            <begin position="73"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="405"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="512" mass="53932" checksum="E1EAB50343265393" modified="2007-12-04" version="1">MAWADRTVPRRCLCRVQMRAEHRWPSCRRRAQREPAVPDLFRLSARLRAAVSPARGALVRLLSATALLCAAGASVNAAPVLLVEADTGRVLEQQDAGKPWYPASVTKLMTVYVALNAVKEGRISFDSLLTVSPLAASQQPSKMGFKPGTQLTLENALRMLMVKSANDMAVVIAEGVGGSMPAFVEEMNDTAERLGMAGTHYNNPNGLPDPGQITTARDLAVLARALIYHFPEQETLFRIPAMRLGKVVYRNYNRLIDRYPGADGMKTGFICSAGFNLVATATRGNKRLIAVILGAPSAVARTEQAAMLLEKGFQPSWSIFASAAPTLNSIQDTGGEPTDMKPYICGGKRKELASENEDDAIFGASGTATSYATQAAAAAGFSGKNPGAALLQNLPPSMPPVDVFIGPKNAPLPPESAFPAEEKKPTAAKPGDKKAHGTATASTGTPPKPQGNAAAARPNATLSNSEKMGLKPQPAPAPKPAQKPAQASADKPKPKTQGNGQDDSAPAQKPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV53</accession>
    <name>A8HV53_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Histidinol-phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidinol-phosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_4268</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172788.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4268"/>
    <dbReference type="EnsemblBacteria" id="BAF90266">
        <property type="protein sequence ID" value="BAF90266"/>
        <property type="gene ID" value="AZC_4268"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4268"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_4_1_5"/>
    <dbReference type="OMA" id="WRTRAYG"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00013"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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    <sequence length="262" mass="28297" checksum="874BBD9CC326711D" modified="2007-12-04" version="1">MSAVALDAFVHDLATRSGEAILPFFRTAIGVEDKGRRKGQSFDPVTEADRAAEQVMRRMITTTFPEHGIIGEEFGNERRDADYVWALDPIDGTKSFISGMPAWGTLIGLLKQGAPVYGMMHQPFIGERFFGDGGSAHYLGPAGKRRLLTRDCGRLEDAILFTTSPLLMNAADRTLFQSVERDVRLSRYGGDCYAYCMVAAGLVDLVIETGLQDHDIVALVPVIEGAGGIVTNWEGGSPVAGGRVVAAGSKAVHEQALKRLNP</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90449.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_4451"/>
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        <property type="gene ID" value="AZC_4451"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4451"/>
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    <feature type="domain" description="Amino_oxidase" evidence="1">
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    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90449.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="468" mass="48387" checksum="F843309749FCA09F" modified="2007-12-04" version="1">MVPPDPFRSPADGAFEARRVLRGLTRRALLAGAFALPAFARALGQGTAGPVDVIIIGAGAAGIAAARKVAAAGRTYALIEASKRIGGRVLTDTASFGLPLDLGASRLYLPGASSLAELARQSGGELDLAPSGARLYTGAREATDTQYEDFAATVRRVERAIGAAGDAGRDLPAARVLPPDLGAFGAAASFFVGPLRCAKDLDQVSTVDFSRAEDREEALLAPNGFGPLLAQLASALTVRMDTAATSVDIGSRIVEVRTNRGTVTGRTVVVAVPPSLMLAGKLRILPMLPTRQRAAVERITLGAREKVAFLLPGNPLRAADDETIIVQAGTQRPLVLKARVGGSDLHVAEVGGPQAQALSDGGSNAGADYVKAALIADFGTDIGKRMGKVVQTRWSKEPWTLGGISCALPGSGNMRRAFTEVVANRLIFAGEHTHETLWGTLAGAWASGERAAGQALRLLGVQGASLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <begin position="1"/>
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    <sequence length="98" mass="10948" checksum="DB872228AB6E4CC7" modified="2007-12-04" version="1">MSPQQSRSSLGASKVQVRPASRSNVQIAPSAAVPDRVLTPETPAPMPRPAGLMGLIRLWMWRVRSRAELAELDAERLRDAGIHPRLARREADKPFWRA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1461"/>
    <dbReference type="EnsemblBacteria" id="BAF87459">
        <property type="protein sequence ID" value="BAF87459"/>
        <property type="gene ID" value="AZC_1461"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1461"/>
    <dbReference type="eggNOG" id="COG2968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080344_4_0_5"/>
    <dbReference type="OMA" id="LPNGPHI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="285" mass="30083" checksum="9DCF4B019A7D3974" modified="2007-12-04" version="1">MSRPWGGVRRLGEVFTNARHKRPSLDMQMRERAGRSPVAGGNWMRIAPRWNAAVAAAVLTAGLVMGATAQAEEFARSTLTVVGQGRASARPDIAMVTTGVVAAGKTAEEALAANSKAMEQVIAAIKDAGVEPKDISTSGLSVQPQYSQPGKDSREAPKVVGYEVRNAVTVTVRDLALVGTLLDKVVQAGANQASGLSFQLADASPLQLQARVAAVKDAQAQAQQIADAAGVRLVRIRRIDPRGGDNYLALPAPMPMKAEARAVPVESGEMDVRAQVSIVYEIEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX65</accession>
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            <fullName evidence="4 5">Ribonuclease H</fullName>
            <shortName evidence="5">RNase H</shortName>
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    </protein>
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        <name evidence="5" type="primary">rnhA</name>
        <name evidence="7" type="ordered locus">AZC_1466</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RNase H family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169994.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1466"/>
    <dbReference type="EnsemblBacteria" id="BAF87464">
        <property type="protein sequence ID" value="BAF87464"/>
        <property type="gene ID" value="AZC_1466"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1466"/>
    <dbReference type="eggNOG" id="COG0328">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030894_6_0_5"/>
    <dbReference type="OMA" id="MQEIEIF"/>
    <dbReference type="OrthoDB" id="1953872at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00042">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="6">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="150" mass="16658" checksum="CD55AC970BFCE06D" modified="2007-12-04" version="1">MSRVEIWTDGACSGNPGPGGWGAILRSGPHEKELKGGEALTTNNRMELMAAISALEALKKPCGVDLHTDSEYLRNGITKWMFGWKRNGWRTADKKPVKNQDLWERLDAALHSHDIAWHWVKGHAGNELNERADQLARDGMAPFKMGGRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXC6</accession>
    <name>A8HXC6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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    <sequence length="259" mass="28043" checksum="7B8477417C7FA526" modified="2007-12-04" version="1">MIKRRLYVEERESRLARWSFRLALFAIPVIVLAAALYRTGVLDFQLALATLGAGLAVALVGAILAVVACVSIWESGWRGMGRSIGALAIALGVVAVPAAVLARGAMLPPLTDITTDPSDPPRFRAMGLVRPRTANSLVYAGDTAAQLQRDAYPGIKPMDLDATPDEAFNALLALVQKRKWHILDAVPPRGTLRDGQIEAVAPTPLIGFRNDVVIRVRPTAKGTRIDVRSASRYGFHDLGENAMRISSLMADLTAERRKR</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173010.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4491"/>
    <dbReference type="EnsemblBacteria" id="BAF90489">
        <property type="protein sequence ID" value="BAF90489"/>
        <property type="gene ID" value="AZC_4491"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4491"/>
    <dbReference type="eggNOG" id="COG3605">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007308_7_1_5"/>
    <dbReference type="OMA" id="MFPMISE"/>
    <dbReference type="OrthoDB" id="467393at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="GAF" evidence="11">
        <location>
            <begin position="24"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF90489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="755" mass="82173" checksum="E32DEA781FF43160" modified="2007-12-04" version="1">MRGALGGPRVLLRRLREVMAEPISAQDRLDKIVVLIAANMVAEVCSVYVLRVDATLELYATEGLNRDAVHLTVMRTDEGLVGHVAREAESLALSDAQNHPEFSYRPETGEEIYNSFLGVPILRGGNTLGVLVVQNRARRTYTDEEIEALQTTAMVMAEMIASGELTALAKPGAEPAAQRPLHLKGTALADGLGLGHVVLHEPRVVVTNVIADDVHKETARLDGAIGKLRASIDLLLEDDGLSKAGEHREILEAYRMFAHDRGWMHKMREAVQTGLTAEGAVERVQSDTRARIMRASDPYLRERLHDLDDLANRLLRELTGRGRPSERADLPENAILIARNMSPAALLEYDRSRIRGLVLEEGGTTSHVTIVARALGIAAVGQVENATSLAETGDPVIVDGQAGEVHLRPPGDVEEAYAEKVRFRAKRQARYAALRDLPNVTKDGAAVDLLLNAGLLVDLPHITETGAAGIGLFRTELQFMVASTFPRISEQLRLYRAVLDAAGDRPVTFRTLDIGGDKVLPYMRTVEEENPALGWRAIRLGLDRPGLLRSQIRALLRAAAGRELRVMFPMVADVAEFDQARTILERELTHLRKHGHSLPEKVYAGAMVEVPSLLFQLDEILSRADFLSVGSNDLVQFLFAADRSNVRVADRFDPLSPAALRAFRMVAQAGARHGKPVTLCGELASRPLEAIALAAVGFRALSLSPAAVGPVKSVLLDLDLGAARALIEPLLADTTGTADIRARLKDFAETSGLSF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-03-18" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYS9</accession>
    <name>COAA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pantothenate kinase</fullName>
            <ecNumber evidence="1">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">coaA</name>
        <name type="ordered locus">AZC_4496</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic pantothenate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173015.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HYS9"/>
    <dbReference type="SMR" id="A8HYS9"/>
    <dbReference type="STRING" id="438753.AZC_4496"/>
    <dbReference type="PRIDE" id="A8HYS9"/>
    <dbReference type="EnsemblBacteria" id="BAF90494">
        <property type="protein sequence ID" value="BAF90494"/>
        <property type="gene ID" value="AZC_4496"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4496"/>
    <dbReference type="eggNOG" id="COG1072">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053818_1_1_5"/>
    <dbReference type="OMA" id="RKYTQVS"/>
    <dbReference type="OrthoDB" id="1793376at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02025">
        <property type="entry name" value="PanK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00215">
        <property type="entry name" value="Pantothen_kinase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004566">
        <property type="entry name" value="PanK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285:SF139">
        <property type="entry name" value="PTHR10285:SF139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000545">
        <property type="entry name" value="Pantothenate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00554">
        <property type="entry name" value="panK_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000325543" description="Pantothenate kinase">
        <location>
            <begin position="1"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="98"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00215"/>
        </source>
    </evidence>
    <sequence length="320" mass="36973" checksum="DCCEFA9208FBDAFA" modified="2007-12-04" version="1">MDQRLDPGLSPYRTFTRAEWAQLREDTPMTLGAEEILRLQGLNDRLSIREVEEIYLPLSRLLSMYVGATQKLFRAMSQFLDHRNNAEGKMPYIIGVAGSVAVGKSTTARVLQALLARWPHTPKVDLVTTDGFLLPNAVLQREGLMEKKGFPESYDLSLLLRFLTDIKAGRRPVKAPLYSHFFYDVLPDQMVEVDRPDILIVEGLNVLQTGRPPRDGKAIPFVSDFFDFSVYIDADEDVLEHWYVQRFMRLRETAFKDPLSYFHRYSKLTEEEARETALSIWHRINLTNLRENILPTRQRANLILRKAGDHEVAEVQLRKL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ95</accession>
    <name>MURC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="1">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">murC</name>
        <name type="ordered locus">AZC_4556</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MurCDEF family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173075.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HZ95"/>
    <dbReference type="SMR" id="A8HZ95"/>
    <dbReference type="STRING" id="438753.AZC_4556"/>
    <dbReference type="EnsemblBacteria" id="BAF90554">
        <property type="protein sequence ID" value="BAF90554"/>
        <property type="gene ID" value="AZC_4556"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4556"/>
    <dbReference type="eggNOG" id="COG0773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028104_2_2_5"/>
    <dbReference type="OMA" id="DITYQLR"/>
    <dbReference type="OrthoDB" id="307881at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0131">Cell cycle</keyword>
    <keyword id="KW-0132">Cell division</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071094" description="UDP-N-acetylmuramate--L-alanine ligase">
        <location>
            <begin position="1"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="114"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <sequence length="467" mass="50013" checksum="1C4EF1B81BB4DDFC" modified="2007-12-04" version="1">MKLPEALGSIHFVGIGGIGMSGIAEVLNNLGYTVQGSDVAENANVKRLRENGIAVTVGHKAENIDGAEVVVVSSAIKRDNPELLAARAKRLPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSLVATLLDKGGFDPTVINGGIINAYGTNARLGAGDWMVVEADESDGTFLKLPAEVAIITNIDPEHLDHFKTFDKVQEAFRTFVENVPFYGFAVMCIDHPVVQALVGRIEDRRIITYGENPQADVRLVDVDLRGGITRFGVVFRDRAGTAEHRIDGLKLPMPGKHNALNATAAIAVARELRVPDDRIIEAIGGFGGVKRRFTRTGEWKGATIFDDYGHHPVEISAVLRAARAATEGQVIAVVQPHRYTRLASLFDEFCTCFNDADHVIVAPVYAAGESPVPGADSEHLVQGLRARGHRSVTALKGPEELAGLVAGLAKPGDFVICLGAGTITQWAYALPGELEKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZJ1</accession>
    <name>A8HZJ1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_4589</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4589"/>
    <dbReference type="EnsemblBacteria" id="BAF90587">
        <property type="protein sequence ID" value="BAF90587"/>
        <property type="gene ID" value="AZC_4589"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4589"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_5"/>
    <dbReference type="OMA" id="QHIRKTP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="30"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="294" mass="32854" checksum="FD42091DD64E9DF9" modified="2007-12-04" version="1">MNGRQNGGDARQKWPAHLRHREDGLGTTLLDVRDVSLRFGGLRALSDVSFSVEKGELFSIIGPNGAGKTSLLNCISGRYSPSEGKIFFGGRDITRLKPNRRAAIGIGRTFQNLALFHHMSVLDNIMVGRHHLLKNNFLTGALYWFGGAQKEELEHRRKVEDVIDFLDIQHVRKATAGTLSYGLRKRVELARAVALEPELILLDEPMAGMNLEEKEDMARYIVDLNEEWGMTIIMIEHDMGVVMDISHRVMVLDFGRKIAHGQPADVLADPHVRKAYLGEEDPEIEPATPQALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I054</accession>
    <name>A8I054_AZOC5</name>
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        <recommendedName>
            <fullName evidence="8">Membrane fusion protein (MFP) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hlyD</name>
        <name evidence="12" type="ordered locus">AZC_4667</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4667"/>
    <dbReference type="EnsemblBacteria" id="BAF90665">
        <property type="protein sequence ID" value="BAF90665"/>
        <property type="gene ID" value="AZC_4667"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4667"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023976_1_1_5"/>
    <dbReference type="OMA" id="WQSERDN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010129">
        <property type="entry name" value="T1SS_HlyD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01843">
        <property type="entry name" value="type_I_hlyD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="11">
        <location>
            <begin position="107"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="139"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="13"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF90665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="482" mass="52276" checksum="2EF6601B3FAC0C74" modified="2007-12-04" version="1">MSDTAITPNAGAKPPASPTPPSSSLAPAPVSTPALPPANPTRLDFSAPPPEVKSDMRRVAAIGYGLIFLTFGIGGAWAALANIDSAIIANGVVSVESKRQVVQHLEGGIIVEIDVKDGESVKAGDLLFRLDPTSSQSNYAALRGQLDTLQATEARLEAERAQADTVVFPAALLARENEPLVRSVIADQRAQFRDRKASLNGQIDILNSRARQGETEIDGLKREREALDSQLFYIEDELTGIRSLSDKGLVSKPRLAELQREKARLQGLVGRNTADAAKAQNTIGEMKLQIQQLLQKQQEDVAQQMVETRQKISDVTEKLAVSENVLKRVDIRAPRAGVVQNINPRIYTIGAVVKPGDTLLEIVPQNDELIVDAQVAPTDVDRLHDGITGVEVRFTAFHSRTTPLILGELRSVSPDRLVDEATKQPYFQAVVAVAKTDIPEDMKARLRPGMPAEVVIGTGERTVLSYLTRPLVDAVTKSLREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1A3</accession>
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        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <property type="entry name" value="YdfO-like_sf"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="BAF87379.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    <sequence length="133" mass="14415" checksum="0E4B2DD46784C8C1" modified="2007-12-04" version="1">MNAEQTTCARACLEAAETDAMAFPDIVGKLIGAGFESYAIDFRRGSALYYLPSGESIELAIATEPTPVEEHFNTADLLEAIREAQSRAPGYSYKGFCRKAKAAGCAGYLVSFSGRRAVYFGRTGETHVELFPQ</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1648"/>
    <dbReference type="ESTHER" id="azoc5-a8i3s2">
        <property type="family name" value="CarbLipBact_2"/>
    </dbReference>
    <dbReference type="MEROPS" id="S09.946"/>
    <dbReference type="EnsemblBacteria" id="BAF87646">
        <property type="protein sequence ID" value="BAF87646"/>
        <property type="gene ID" value="AZC_1648"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1648"/>
    <dbReference type="eggNOG" id="COG1647">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_076594_1_0_5"/>
    <dbReference type="OMA" id="DWYAEVD"/>
    <dbReference type="OrthoDB" id="1694750at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012354">
        <property type="entry name" value="Esterase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017388">
        <property type="entry name" value="Esterase_lipase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="18"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="292" mass="31757" checksum="5D1F49C838F27E53" modified="2007-12-04" version="1">MMAIIDRSFMIEGGPVGVLLIHGLGGTPVEMREVARALAAGGHTVLCCQLAGHGGSMDDLTSTGFEDWYDSALAGLATLEQRCERVVVGGLSMGAVLAALLAARQPERVAGLVMLAPTLRYDGWSIPWYSFLLPLLINTPIGRRYQFEEREPYGVKDERVRAVIVRALRQGSGDAGLTATPSAALRELWRLVAALRPLLGAIRQRTLLVHARHDDVASLRNALYLQRHLGGPVDSLILEDSYHLVTLDRQRHLVTERVLSFVDALTAPKSNPKARRPAARAALVPQEMGHVA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3Z3</accession>
    <name>NUOD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADH-quinone oxidoreductase subunit D</fullName>
            <ecNumber evidence="1">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NADH dehydrogenase I subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NDH-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nuoD</name>
        <name type="ordered locus">AZC_1670</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 49 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170198.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I3Z3"/>
    <dbReference type="SMR" id="A8I3Z3"/>
    <dbReference type="STRING" id="438753.AZC_1670"/>
    <dbReference type="EnsemblBacteria" id="BAF87668">
        <property type="protein sequence ID" value="BAF87668"/>
        <property type="gene ID" value="AZC_1670"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1670"/>
    <dbReference type="eggNOG" id="COG0649">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_1_1_5"/>
    <dbReference type="OMA" id="IMGTSME"/>
    <dbReference type="OrthoDB" id="473681at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050136">
        <property type="term" value="F:NADH dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01358">
        <property type="entry name" value="NDH1_NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014029">
        <property type="entry name" value="NADH_UbQ_OxRdtase_49kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022885">
        <property type="entry name" value="NDH1_su_D/H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11993">
        <property type="entry name" value="PTHR11993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01962">
        <property type="entry name" value="NuoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00535">
        <property type="entry name" value="COMPLEX1_49K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000357762" description="NADH-quinone oxidoreductase subunit D">
        <location>
            <begin position="1"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01358"/>
        </source>
    </evidence>
    <sequence length="402" mass="45219" checksum="747A27C05E8ACFEB" modified="2007-12-04" version="1">MAHTLDSQQPAVPVRNFQINFGPQHPAAHGVLRMVLELNGEVVERVDPHIGLLHRGTEKLIEAKTYLQAVPYFDRLDYCAPMNQEHAFCLAVERLAGIEVPKRGQLIRVLYSEIGRLLSHLLNVTTFAMDVGALTPPLWGFEAREKLMMFYERASGSRMHAAYFRPGGVHQDLPQKLVEDIGEFCRTFPSLLDDLDALVTGNRIFKQRTVDIGVVTLEDALAWGFSGVMVRGSGAPWDLRRAQPYECYSELDFDIPIGKHGDCYDRYVVRMEEMRQSNKIMLQCVDRLLKEAGPVASTDRKVSPPKRGEMKRSMEALIHHFKLYTEGFHVPEGEVYAAVEAPKGEFGVYLVGDGTNKPYRCKIRAPGFAHLQSMDFLCRGHMLADVSAVLGSLDIVFGEVDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4P8</accession>
    <name>A8I4P8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1757</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1757"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87755">
        <property type="protein sequence ID" value="BAF87755"/>
        <property type="gene ID" value="AZC_1757"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1757"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025996_17_2_5"/>
    <dbReference type="OMA" id="HAGWARR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="63"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="420" mass="45231" checksum="C50D1C6A03D7971B" modified="2007-12-04" version="1">MERLRVDLPVPPPNLLVYSAGRADGRGKWPREVGGTRSMADQPLSFRVVAPPRRALVAPKAIVAIPVKDEEVRLLECLKALAAQRDAPDFATIVLLHNCLDRTEQVAIQAGETLPLPLRILSIELASDKAGASWARRHVMDAAASLFVTSGLPKGIILTTEADARPAPNWVAANVADIALGADAVAGRVEMDANQSLPKGLWRRYQGAHRYARLLNEVDHLIDGEHGSPWPTHREASSASLAVSVDAYVKAGGIPTSASAAASGLLGALTRTGHSVRHDPDVQVAASWRLDPAGIGGQFRAWSEGQVAFDTLGLEPVAQVVRRARLRRTMRRAFGAGQLWTVTNWASTLRISPVDAFKLAALPSFPQMWAVLENISPLLTPHPLAPSQLTLETARAVGLLAEMRIRSGVRRLLGRKEPDA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4S6</accession>
    <name>UREE_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Urease accessory protein UreE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ureE</name>
        <name type="ordered locus">AZC_1767</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UreE family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170295.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I4S6"/>
    <dbReference type="SMR" id="A8I4S6"/>
    <dbReference type="STRING" id="438753.AZC_1767"/>
    <dbReference type="EnsemblBacteria" id="BAF87765">
        <property type="protein sequence ID" value="BAF87765"/>
        <property type="gene ID" value="AZC_1767"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1767"/>
    <dbReference type="eggNOG" id="COG2371">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093757_1_0_5"/>
    <dbReference type="OMA" id="AYDARCK"/>
    <dbReference type="OrthoDB" id="1663151at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065003">
        <property type="term" value="P:protein-containing complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019627">
        <property type="term" value="P:urea metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00571">
        <property type="entry name" value="UreE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00822">
        <property type="entry name" value="UreE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012406">
        <property type="entry name" value="UreE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007864">
        <property type="entry name" value="UreE_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004029">
        <property type="entry name" value="UreE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036118">
        <property type="entry name" value="UreE_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05194">
        <property type="entry name" value="UreE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02814">
        <property type="entry name" value="UreE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00988">
        <property type="entry name" value="UreE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69287">
        <property type="entry name" value="SSF69287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0533">Nickel</keyword>
    <keyword id="KW-0996">Nickel insertion</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000072875" description="Urease accessory protein UreE">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="208" mass="23323" checksum="085E470C7CCBC1BA" modified="2007-12-04" version="1">MIRSTKIVRHLAVRPDRVVDTITLDHHARHRRRVAMTADGGLEFLLDLDRAAVLDHGDALELEDGRLVQVKAADEQLVEITTFNPVRLMRAAWHIGNRHIPAEITEEAIYIVQDPVLEAMLRGLGAAVKPVVRPFKPERGAYEAAEAHGHGQAHAHDHHDHDHHDHGHDHAHHDHAHHDHAHDHHGHDHAHDHAHGASCGCGHTHHHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I530</accession>
    <name>A8I530_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_1805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170333.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1805"/>
    <dbReference type="EnsemblBacteria" id="BAF87803">
        <property type="protein sequence ID" value="BAF87803"/>
        <property type="gene ID" value="AZC_1805"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1805"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_5"/>
    <dbReference type="OMA" id="RINCVNS"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="320" mass="35053" checksum="2911930D90F77170" modified="2007-12-04" version="1">MNIRFLETFVWVARLRSFSSAADKLCTTQAAVSNRIATLERDLGVRLFERDLRNVSLTPQGERALAQAETIVRLTEELRLGVSEASSLRGRIAIGTIDSIVYAWLPKLIEAVKATYPDVDIDLTVDNSLTVSRLLLDRQVNLALIAGPVLAAECSNIDLCTYQCHWFAAPHLGLHGRRLSLVDIVANPIFAFSKGSQPHQNVLRLMESAGLDANLNLVRILNSNSLATITRLARDGMGVAVLPTEVAREMVERGELMQLDVDADLPPLHLHAVYREEPGSTLPALIARMAAQVAKAEDAATLTPSANARRNQIRIASHTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5E9</accession>
    <name>A8I5E9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170797.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2270"/>
    <dbReference type="EnsemblBacteria" id="BAF88268">
        <property type="protein sequence ID" value="BAF88268"/>
        <property type="gene ID" value="AZC_2270"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2270"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_3_4_5"/>
    <dbReference type="OMA" id="YVSQCMS"/>
    <dbReference type="OrthoDB" id="775108at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="73"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="284" mass="30544" checksum="8D2E48006F108161" modified="2007-12-04" version="1">MKLLRYGPAGQEKPGLLDEAGKIRDLSGVISDLTGEAITPEGLAKLKTLDVSSLPVVEGTPRYGAPVANVAKFIAIGLNFTDHAAESNLPIPSEPVVFMKATSCIQGPNDAVVIPRGSKKTDWEVELGIVIGKRASYVTKDEALDHVAGYVLINDVSEREYQIERGGTWDKGKGCDTFGPIGPWLVTSDEVGDVQQLGMWLDVNGQRRQTGNTSTMIFDVKTIVSYLSEFMTLLPGDIITTGTPPGVGMGIKPEAVYLKAGDVIELGIDKLGRQKQTCVAWEKK</sequence>
</entry>
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        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2301</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2301"/>
    <dbReference type="EnsemblBacteria" id="BAF88299">
        <property type="protein sequence ID" value="BAF88299"/>
        <property type="gene ID" value="AZC_2301"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2301"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_061126_1_0_5"/>
    <dbReference type="OMA" id="YANDGDW"/>
    <dbReference type="OrthoDB" id="1690667at2"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
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    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
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    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
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        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="10"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="268" mass="30546" checksum="7FC1545E1D0DC897" modified="2007-12-04" version="1">MSDSPEERRFRALFISDVHLGTKGCQADLFLDFLKYHDADTIYLVGDIVDGWRLRASWYWPQKHNDVVQKLLRKGRKGARIVYLPGNHDEFLRDYYGMHFGGIEVVESIIHETAAGKRYLVIHGDVFDVVVRHAKWLAFLGDGAYSFALLVNTYVNLVRRKLGLTYWSLSQWAKLKVKNAVNFIGKFEEALAEEARRQKVDGVICGHIHHAIEHDTHGVHYVNCGDWVESCTAIAEHEDGRLEIIYWAKQVRAAELSGEPLQGARAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5T3</accession>
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        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
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        <name evidence="2" type="ordered locus">AZC_2318</name>
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    <organism evidence="2 3">
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        <lineage>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Lee KB."/>
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            <fullName evidence="2">Putative DNA polymerase III delta prime subunit</fullName>
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    </protein>
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        <name evidence="2" type="ordered locus">AZC_2174</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2174"/>
    <dbReference type="EnsemblBacteria" id="BAF88172">
        <property type="protein sequence ID" value="BAF88172"/>
        <property type="gene ID" value="AZC_2174"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2174"/>
    <dbReference type="eggNOG" id="COG0470">
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="353" mass="37844" checksum="733D470F211FADD2" modified="2007-12-04" version="1">MARAPAPKDDGEALEGDVLTGAPHPRRQDRLFGHAEVEADLMAEWRSGRLPHGLLIGGPEGVGKATMAYRIARFVLSGGAAPASQHSFDVPESHPVWRQVAALSHPDLLVLRRVPEPGEEKIPTVIPAEMVRKVRNFFGATAGSGGWRVCIVDAVDDLNAFGANALLKTLEEPPPRALFLLVTHAPGRVLPTIRSRTRAVRLKPLGGAEVLAALDHLAPALALEEADLPAAAAASGGSVRRAIVLARGEGMEVRAATQRALEQLPQPRMEELHALGARLQGDRGDGLDLFLETVSDWIAAEATSGLAGRARLVRLGEVWEKVRRSGAEADIYNLDRKALVFRIFTELAEAARA</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF88221"/>
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        <property type="entry name" value="Lysozyme-like_dom_sf"/>
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        <property type="entry name" value="Peptidoglycan-bd-like"/>
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    <evidence type="ECO:0000259" key="1">
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    <sequence length="421" mass="46682" checksum="CF24009AA41A20CF" modified="2007-12-04" version="1">MDDHMRPARHGIDRRLFLGALTAGTAGFLTPGLALAQSAAQPFGTWVEKFRARARARGISDATYSRVFATVKPDPSVFEADRAQPEFQEETWQYLNRRVSDWRIATGRQRASEYAALFTRIENDFGVDRAVMLGYWGMESAFGDVVTNPRHMKPVFNSLATLAWGDPRRRKYWETELLNALVIVERGWSTPQEMVGSWAGAMGHTQWMPEVWLNMGVDYDGNGRISPFGKPDDALAGTANFILKRGRYRKGEPWGIEARLPAGFNTQLADNKTWRPLSAWGGMGLTMVEGQSITEYDNPARLWLPGGAGGPALLLLHNFYAVRSYNPSSAYALAVVHLGDRVMGGEPFRTPWPGGERTLTLAELQEIQQRLTRLGFDTGGTDGRVGNDTMRAVKAFQQRAGLTPADGYPGLQVLTALRGAR</sequence>
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            <fullName evidence="6">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2659</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171183.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2659"/>
    <dbReference type="EnsemblBacteria" id="BAF88657">
        <property type="protein sequence ID" value="BAF88657"/>
        <property type="gene ID" value="AZC_2659"/>
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    <dbReference type="KEGG" id="azc:AZC_2659"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_017028_7_3_5"/>
    <dbReference type="OMA" id="PQSACNY"/>
    <dbReference type="OrthoDB" id="162819at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724235" evidence="4">
        <location>
            <begin position="32"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="86"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="538" mass="59033" checksum="681A522ED2FDE9B0" modified="2007-12-04" version="1">MSGPFVDRRSFSLGLAASLGLAPLAGRAAFAAGADAGGTPVRGGVLRFLVEQEPTTLVTIAHTAGPSTRVSPKVTEGLLQYGFDYEPKPQLATEWSESPDGLTYVFKLRPNVKWHDGKDFTSADVAYSIKLLKENHPRGRATFSSVTVVETPDPLTAIIRLSKPAPYLLVALDASESPIVPKHLYEGTDPLTNKNASAPVGTGPFVFREWVKGSHIILDRNPNYWDPGKPYLDRVVVRFIADQSARSAAFETGELDLGGGPPVPRSDLARIQALPNIGSDTRGYEYNGNMTQLFFNFDTPVLKDKKVRLAIAKAIDHKKLLDVVYFGYGTIAPSPLGVDVKKFIDPNIKTYGFDLSAANKLLDEAGYPRKADGTRFPLRLYANPYNSQASGDFVKQALARIGIPVDFQFFDFSTYLQKAYTVRDFDLTLESLSTTFDPTPGVQRVYWSKNFKIGLPFSNASHYDNPEVDALLEAAAVEADEEKRIAIWRKFQQVTHDDVAAVNLISPAGVTLFNKKVKNHTLGVTGVNASFADVYFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
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        <name evidence="3" type="ordered locus">AZC_2671</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171195.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2671"/>
    <dbReference type="EnsemblBacteria" id="BAF88669">
        <property type="protein sequence ID" value="BAF88669"/>
        <property type="gene ID" value="AZC_2671"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2671"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="KQCVIAD"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="297" mass="32304" checksum="30F2B4C33EA338E0" modified="2007-12-04" version="1">MRINFELLDLRAFLAVIDHGGFHRAAEVLNLSQPALTRRVQALEATVGVPLLERTTRRVALTSAGRSFAPLARRLIGDLEESLLGIAGVGGRQGGQITLACVPTAVVYFLPEAIERFAAEFPRIRFRILDLSANDGLEAVRTGEAEFGINLVGSSDPDLTFTPLIEDPFVLACRSDHRLAKLTSVSWKDLQGEPLIGVSRASGNRLTLENALAGAKVQLDFQYEVNHLATSLGLVERGLGVSVLPKMATPSDHPVIVTKPIKAPVVRRTIGLVERRTSRLSPAAKKFRDMLVEHLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2719</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171243.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2719"/>
    <dbReference type="EnsemblBacteria" id="BAF88717">
        <property type="protein sequence ID" value="BAF88717"/>
        <property type="gene ID" value="AZC_2719"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2719"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008878_2_0_5"/>
    <dbReference type="OMA" id="PGYYIHE"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="1">
        <location>
            <begin position="235"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="2">
        <location>
            <begin position="452"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="589" mass="64149" checksum="9BEA79EE13A41F27" modified="2007-12-04" version="1">MARKLPKKDVVIIGLGWTGSLLAHELTDAGLDVVAIERGPWRDTSTDFSPTQDPDELRYGIRLDLFLRPAQETFTLRHNVAQQALPIRWPGAFIVGNGVGGAGVHWNGHTWRFLETDFTLKSHLTQRYGASALPEDMQIEDWGVTYADLEPYYDKFEYIAGTSGRAGNIQGKMQAGGNPFEGPRTRDYPLPPLKDTAPTALFAKTASEMGYHAFPRPASNASEAYVNPLGIAMGPCTYCGFCERFGCGNYSKASPQANVLPVLMRKSNFSVRTECEVLHINKHPGGNVATGVTFVDSSGEEWDQPADIVLVCAYGLHNVRMMLLSGIGQPYDPKTGEGVVGRNYAYQSAGAAGLLFEGKRFNPFVGAGSLGQCIDDFNGDNFDHAGLGFVGGASITTSNYHGRPIAMSATRAPGTPAWGSAWKKQVASTYQNTSAVAGQGSVYSYRDKYLDLDPVYKDRFGRPLLRMTFDWHENEKKMTRFIAQKCAEIGKAMGAKHVTPRSLPDHFNVVPYQSTHNTGGAIMGDNPKRSAVNRYLQSWDAHNVFVIGASAFPQNAGYNPTGTVGALALWAADAIRNQYLKNPGPLVQA</sequence>
</entry>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171245.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2721"/>
    <dbReference type="EnsemblBacteria" id="BAF88719">
        <property type="protein sequence ID" value="BAF88719"/>
        <property type="gene ID" value="AZC_2721"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2721"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="TNESAYF"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
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        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="64"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="258" mass="28072" checksum="FE7AC6ABC765DCCE" modified="2007-12-04" version="1">MGALDTAVVILRCFSEARPELSFAEIMTATGMPKSSTSRMLSALREARLLEQDEVTRRFRPGLLAFELGRLYRAHDDLISRTETALKDVCARTGHTGYIAVLDGCDQLVLRMVPGSNPLRVVSPAGQRGSALATSNGRAMLARLSDAEILARLPKPFPKLPRNCPQSPDELFQRIAEIRRTGRSMSDNEAIEGVASQGFALCSRETSEMIGIAISYASQATPPDERAHVAREMEAMARSVGRAIGDAVWGLETGEQAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8I920</accession>
    <name>A8I920_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2733</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171257.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2733"/>
    <dbReference type="EnsemblBacteria" id="BAF88731">
        <property type="protein sequence ID" value="BAF88731"/>
        <property type="gene ID" value="AZC_2733"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2733"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_2_5"/>
    <dbReference type="OMA" id="IYYANAR"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071705">
        <property type="term" value="P:nitrogen compound transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="62"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="278" mass="30264" checksum="1C74EADFD1A3CBC2" modified="2007-12-04" version="1">MTGPLPDISGYSIAPQRHWGRWIAVAVILLLLAALARAFAVGMIEWQFVGTFLTAPVILTGLLNTIVMTFAAMGVGIVLGVITAIMRMSPNPVLRGVAMGYVWLFRGTPVILQLLLWFNLALIFPRLGISGWWTVRTVEVMTPVVAALLGLGINQGAYTSEVVRAGLLAVDTGQYEAAKAIGMTRLLALRRIVLPQAMRVIIPPLGNEFIGMVKLTSLASVIQFTEILHSAQNIYYANSRVIELLIVAAIWYLAIVSLLTPLQMLLERRFARGTAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9A6</accession>
    <name>A8I9A6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2764</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Lee KB."/>
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    <sequence length="643" mass="67535" checksum="F81847AF93CD78EC" modified="2007-12-04" version="1">MMKTGIIEHLGHRDVLLPGLIAEALRANDRAKVRLSVLQAAARHAAAPDASRSPLTQECRTAGLDPVAMEELVASAVADAAGQVSAPGIASLGEAIWGDVEAMAQGVAAADPGAAEPAQARLLALREAHALGRTDSIAAGEVARLTGLPGETGDSLHRLIMDLHRALSRLAVAHAEEDVAGARASGLTTGDRRLVEAFMRGLNATRGLKFDHPGLGTHAARSGEHLTIQNDIGETDAHVVVITVEPEAVSVTYTDVHLRRARFFTGLLSDVPLAWSGLDRKTAEGLADEGVFYLVTGRCESPDAAIREAVLEAIGANLVFLIDWNKARKVLRTAIPKEEAVRVLEWAARHRCGQRAFLELGGGELLAAAVQHAAPARIGFGERLDGVLGRDGAVDFLKSVLRICAETLKEGSSARLARDRIEAELMRHLERIEATLFAIVVRQAGLAREVAAEVAAALVAERSGVGFDHTALAAAARRREEKADRLALDARQKAARFEAAPAIQRLSDHVEEAVDELEQAAFIASLLPANVPSDILAPLSQLCAAAVRGAEAAASGAAAAAAVPAGQRIDAEDALASADLLADLEHIGDAEERTVTGRVLRGGADLTVALCALDLARALERATDRLAGYGHALRGHVLAELAL</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Lee KB."/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="2" id="KW-0808">Transferase</keyword>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="424" mass="42942" checksum="0BFDE22317AB8F73" modified="2007-12-04" version="1">MTLLLGCIADDYTGASDLANTLTKAGLRTVQTIGVPAADFALPDVDAVVVALKSRSIPATEAVALSRGARDFLGGEGARHILFKICSTFDSTDAGNIGPVTDALRADASAGPVLVTPAFPETGRTVYFGHLFVGAVPLNESPLKDHPLNPMTDANLVRVMARQSAAPVGLVDLHTVARGPEAVRSRLAVLAQEGKGAAIIDAVFERDLETIGAVALDEPLSVGASGLGLGLARTLAAGRTAPTDGAVRWGASVPGAIAAIAGSCSAATLEQIARAEENMPVLRLAAEQLVTDGAAVVAEAIGWARERLAHGPVLIAASGTPQEVAAVQARHGRHASGLAIEQASAALAAGLVEAGVRRLVVAGGETSGACVDRLGIAGFEVGPEIAAGVPLLRTVAYAPQMLLALKSGNFGGPDFFARAFAAMS</sequence>
</entry>
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            <fullName evidence="3">Putative exopolysaccharide regulatory protein</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2814"/>
    <dbReference type="EnsemblBacteria" id="BAF88812">
        <property type="protein sequence ID" value="BAF88812"/>
        <property type="gene ID" value="AZC_2814"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2814"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067747_0_0_5"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
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        <property type="match status" value="4"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="87"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="351" mass="37678" checksum="B6BDB923EBE1B9D7" modified="2007-12-04" version="1">MFGCGADQGRDEWGDRPLCQGESLARPWRGPDLARSGGHAFRIMNVVDHSIGTNGGLGRHGLRRTAWGIVAGLCLLVAGAVSPALAFDGNTDGSGPAGLAPPPGLTPPGSLPLPPGARPVDEAFRSGAQALRLGQTAKGVDALRYAADQGHPAAQWKLGRMYADGDGVKRDDAKAFEYFSRIANLHAEDYPGTPQARFAASAFVALGSYYLVGIPNTAVRRDPARARDMFSYAASYFGDPDAQFRLGKMYLDGTGMSRDPRQAARWLILSAQKGQYEAQALLGQLLFRGDEGIPRQGARGLMWLTLARDGAAGPGDKWVVDLYEDAFSEATEDERAVALKYLEQWLKTAQR</sequence>
</entry>
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    <accession>A8IA61</accession>
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            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
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        <name evidence="12" type="ordered locus">AZC_2468</name>
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    <organism evidence="12 13">
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170994.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2468"/>
    <dbReference type="EnsemblBacteria" id="BAF88466">
        <property type="protein sequence ID" value="BAF88466"/>
        <property type="gene ID" value="AZC_2468"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2468"/>
    <dbReference type="eggNOG" id="COG0157">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039622_0_1_5"/>
    <dbReference type="OMA" id="DMIMLKD"/>
    <dbReference type="OrthoDB" id="1718114at2"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="11">
        <location>
            <begin position="19"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="10">
        <location>
            <begin position="110"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="278" mass="29820" checksum="55BBF1BCE0FD8D28" modified="2007-12-04" version="1">MYDPFQIDRLIDLWLAEDIGYCDLTVQVMIEPDEQGHFYMNAREPMTISGIEIAAAIFRRYDKRLDVEVKVKDGDVVEKGAVLLTVRGPARGILTAERTALNIVQRMSGIATETAKYVAAVAGTKARLIDTRKTTPGLRMIEKHAVTSGGGLNHRLGLDNGVMIKDNHIAVCGGIGPAVARARKSLPTLTKIEVECDRLDQVGEALAAGADVIMLDNMSIPDMKAAVELVAGRVPLEASGGIRLDTIGPIAQTGVNYISTSKITQSAPAVDIGLDEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA90</accession>
    <name>A8IA90_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">iclR</name>
        <name evidence="6" type="ordered locus">AZC_2479</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2479"/>
    <dbReference type="EnsemblBacteria" id="BAF88477">
        <property type="protein sequence ID" value="BAF88477"/>
        <property type="gene ID" value="AZC_2479"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2479"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_0_1_5"/>
    <dbReference type="OMA" id="RYPVRMY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="4">
        <location>
            <begin position="62"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="5">
        <location>
            <begin position="125"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="313" mass="34233" checksum="C2CC92DECEF28F37" modified="2007-12-04" version="1">MCICIAIDGRAANPKFKGIMRKPSRTSLRPASAKPAAPSPVRTERADAGAAVAEKKRSSLFVGSTEKAFQVLHAFDGPLRFMTLADIARASGLDRSAAQRLVHTLETLGYIRRVPDTRNYALTSKVLQFSYSYIRANELIDKASPYLLDISRRLGETTNLHELDGPEVVFVARFPGQHMNNIDIVVGSRLPTFFTSSGTAMLSQLSEEEQREILARTNLSPRTPFTVTDPEALLARVRQAGERGYAMIVNETVMGDISISAPITDEHGRPVAGINISVPTSRWTPERAEAELAQEIQVAATSISKPKLTRVSS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAR6</accession>
    <name>RS19_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsS</name>
        <name type="ordered locus">AZC_2550</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171076.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAR6"/>
    <dbReference type="SMR" id="A8IAR6"/>
    <dbReference type="STRING" id="438753.AZC_2550"/>
    <dbReference type="EnsemblBacteria" id="BAF88548">
        <property type="protein sequence ID" value="BAF88548"/>
        <property type="gene ID" value="AZC_2550"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2550"/>
    <dbReference type="eggNOG" id="COG0185">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_144911_0_1_5"/>
    <dbReference type="OMA" id="FPEMVGH"/>
    <dbReference type="OrthoDB" id="1893906at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000072505" description="30S ribosomal protein S19">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <sequence length="92" mass="10424" checksum="41EE123217B490A3" modified="2007-12-04" version="1">MSRSIWKGPFVDGYLLKKADAARASGRNETIKIWSRRSTILPQFVGLTFGVYNGAKHVPVYVSEDMVGHKFGEFSPTRTYYGHAADKKSKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICK2</accession>
    <name>A8ICK2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell morphology protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; alginate biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171744.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3220"/>
    <dbReference type="EnsemblBacteria" id="BAF89218">
        <property type="protein sequence ID" value="BAF89218"/>
        <property type="gene ID" value="AZC_3220"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3220"/>
    <dbReference type="eggNOG" id="ENOG5032DDH">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057510_0_0_5"/>
    <dbReference type="OMA" id="GCPGWLF"/>
    <dbReference type="OrthoDB" id="1439364at2"/>
    <dbReference type="UniPathway" id="UPA00286"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031811">
        <property type="entry name" value="ALGX/ALGJ_SGNH-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16822">
        <property type="entry name" value="ALGX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0016">Alginate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ALGX" evidence="4">
        <location>
            <begin position="86"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="359" mass="37892" checksum="1B8CE29649313859" modified="2007-12-04" version="1">MRDHRIVAAFLFLACCVGGLVSVAAHLSGPAGRAVLDRFSWQGILTGSFAAAFDRDVAAGAPESAALNGFVDGATYALLKDAGAQVRAGCPGWLFLAEETLEVKGGASHLEARARMAGMIAADLARRGITLVVLPVPDKVAMTPETSCALAVSSQARDRLAAWHAHAAKLKLNEIDVTADWPAPGFLRTDTHWDVSGAAFAAARVAAVVRRLDGEGKTQVTLTEGPDHLRPGDLMRLANLTRTASWFGPAPDTVRDISADIARSGGLLDDAPAPDTVLAGSSYSLNSGFLESLQHALQREVVQRSEAGGGFSGALLALLDKGPEALKPVKLVIWEWPARSLTLPLTAAERRYMEIHAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICL0</accession>
    <name>A8ICL0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">araC</name>
        <name evidence="3" type="ordered locus">AZC_3223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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    </evidence>
    <sequence length="508" mass="55670" checksum="637A8A0A393521B9" modified="2007-12-04" version="1">MLEATDTSENPFDIVIIGLGPVGATLANLLGLKGLSTLVLERESEAYHLPRAVHFDDEVMRVFQTIGLADAILPATRLNPGMRFIDAQGALLMDWPRPQEVSGQGWHASYRFHQPDLERILRDGLQRFASVTVRTRCDAFAFEQDREGVTVRYEELTTGRLRQVRARYVVGCDGARSLVRRFIGSSMDDLGFHERWLVVDAVLRQPKPELGDHTIQYCNPARPATYVRGPGDRRRWEITVLPHEDSRTVVQPQTVWSLLAPWLAPDEADLERAAVYTFHSAVARQWRAGRLLLAGDAAHQTPPFMGQGMCSGIRDVANLAWKLEAVVHGQVGESLLDTYQSERGPDAHAYIEMAVRLGGLINTCGTEAALNAAFRDADGVVRIQSRVPRLGPGIAAGRSELAGSRFAQPRLGDGRLLDDAVGFSFALLASERMWSAASEPVRRRFAAAGVTVVTEATCPALKPLLDAQGVGALLLRPDRYVAGAALDDGDLAALADWPMVYLPQRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID56</accession>
    <name>A8ID56_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane autotransporter barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171409.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2885"/>
    <dbReference type="EnsemblBacteria" id="BAF88883">
        <property type="protein sequence ID" value="BAF88883"/>
        <property type="gene ID" value="AZC_2885"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2885"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001106_0_0_5"/>
    <dbReference type="OMA" id="QANANGW"/>
    <dbReference type="OrthoDB" id="1713183at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012332">
        <property type="entry name" value="Autotransporter_pectin_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013425">
        <property type="entry name" value="Autotrns_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030895">
        <property type="entry name" value="T5SS_PEPC_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12951">
        <property type="entry name" value="PATR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02601">
        <property type="entry name" value="autotrns_rpt"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04393">
        <property type="entry name" value="rpt_T5SS_PEPC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Autotransporter" evidence="2">
        <location>
            <begin position="2168"/>
            <end position="2446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="2446" mass="238530" checksum="093D46E3C8E153B5" modified="2007-12-04" version="1">MSNVISRRAGGRQSSFRAELRLGVSLTALSLALPGILLLPQPAEAGCTTIGNQLVYQCDTNGVNVQPVDGTTSLSVSDMTIPSGWINYSVAPAATSSIVMTLTVSNTTVNATGNGAVNVSSQTLPATITVTLDSDVSLTNTGGSGGLWVRNQVAGDISITSGATIISTGSDALTATSNSGSVTITNTGTVTSTDNRGIYADGSPVGGAAVPVTVNNSGLVNAYLAGIRSIDSLGTSSIENSGTVTSTTKQGLIAWSQSGDVSINNSGSVLARNFIGVQGSADAGNVTIANSGYIEAQRDSSLGPSTTNQGIAASASNNVTVTNTSTGRVIAGSDTGVAVSTDNGILTVTNAGRITGTGGVNANATVGTVTVSNTGTVTATGGTGIVAVSGNGAVGVTNSGTVSATGIGILLDGTTNALTNSGTITTTGTTAVQTGNGDSTITTRGRIAAASASDTAIAMGSGSNRLVLADSATLVGKVTNVSSANTLELNGSATGSLDLGSVGATGNFQGFANLAKSGTGTWTVTGSGSSLTGTAVVNAGTLVVQGALGVSSLTVGSASPATLAISNSGTLSSTTATIGSTPGATGTVTVSGTGSAWSSATWVSIGSNGADGAVTVSNGAQFTSSRTGISTASWEAGSGGTGSLTVTGAGTLWTNTGGVDVGRTAGSTASLTVSDGATARIYNTGIYTGAGANITFTGPGTRVEVGNPNDSTQAAWLSPAGGSILVSNGVSLYTSGTYVGAGTGSPGSPVDPTTMTVTGSTTTWDSGQRIYVGGQTGGVGDGIGTLTVSGGATATTATLGVGMDTLSIGTLVLTGSGTRLTAAANPTYSALGNAYVGYSGSATATVSNGATLRADNAVRLAWASGSTGTLAIGAQAGSAAAAAGAITTPTIAFGDGTGTLVFNHTNTGYILSSAITGTGTINVLAGKTILTGDDSGFTGTTSISGGTLQIGNGGTTGTLGGNISLVGGTLAFNRSDSITYAGSLSGGGALVKSGSGTLTLTGANTYTGGTTISAGTLQIGNGGTSGSVSGAISNAGTLTFNRSDTLTYGGAISGSGSVFKYGTGTLTLTGASTYTGLTSVQGGGLTVNGSLAGNVTLGTGTTLSGSGSIAGNVRVNGGTLSGNQTAPLTMGSLTLASASNVNVTLGAASSSPAFNVLGSLTLDGTLNVTANPGFGTGVYRLFNYGGGLTDNGIDVTSVSGLAASVQTAVSGQVNLLVTDPGQSILFWNGRTVTPTGTVQGGAGTWSASAQTNWTNAAGTLPQAWNGSFAVFQGTAGAVTIDNSAGVVTTTGMQFAADGYQITGGALTLTGPTQTIIRVGDGTAAATSMRAVIDSKLTGAGGINKTDLGTLVLGANNDYTGGTTISAGTLQIGNSFSSLGGNISGDILNYGNISFYRTGKMIISGTISGTGSLTQYAAGLVGVYGTLILTANNTYTGGTTNETWANLQIGNGGTSGSVIGDIVNKGFLYFNRSDDIIYSGTISGSGDLFKDGSGRLILTGINTYTRPTQVRSGELVVNGSLTSTGWVILSTGATLSGSGSIGGRVEVNGGTLAGTQAAPLTMGALVLASQSNVNVTLGAAGGSAPFNVLGNLTLDGTLNVTADAGFGAGSYRIFGYGGTLTDNGLDVSRAGGFVGVIQTSVAGQVNLLVSDIGQTMQFWNGTTTTATGTVAGGSGTWTAGPQTNWTNAAGTAPQPWSAGFAIFQGAAGTVRVDTSAGTVATTGMQFVTNGYLVTGDALTLSGTAQASIRVGDGSAAGAGTVATIASALTGTGGINKNDLGTLILTGANTYTGGTTVTAGTLVGNTTSLTGSIIDNAALVFNQTTTGTYSGTISGTGSLTKTGAGTLILTGTNTYTGGTLISEGTLQIGNGGATGSIVGNVVNNATLVFNRSGTYDFPGTITGSGAVIITGGSTVNFTSAAGYNGNIGVADSSFVLSPNAVSRSSYTIGTGGTISGTGTIGGLTVASGGTAAPGYSPGTLTVAGNVTFLPGSVYSVDVTPSGAHDLITASGTASILGGTVAVNATAGGYSPVTTLTILQASGGVSGTFAGITSNLAFLTPLLGYDANDVYLTLRRNDISFASQALTANQRAVAGAADGLGWSNPVYYALANLPVGAAPAAFDSLSGEAYASSSTVMLQQSIYLRDAVGARLGQALAPATAPSGPETAALAPGLTPTLWMQGFGAWGNAWGNGNAASVSSDIAGVFGGADVALGDRWRVGLMGGYSRTTLDANARNSSGTIDNYDIGLYAGARYGDLGLKAGVSYTWHDAAMTRSVVFSGYSGRNTSGYDAGTTQVFGEAGYTFRLNGMALEPFAGLAYVHLSTNGLTETGSTSALSVSTGDMDTLFSSLGLRVGSSLTLAPGVTVSPSLSLAWLHAFGDVAPASTTAFATGSQPFTVTGVPLARDSALIGAGLDYRINANAVLSATYSGQFASGIQDNAFKGMLTVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDL0</accession>
    <name>A8IDL0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CoxF protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">coxF</name>
        <name evidence="3" type="ordered locus">AZC_2957</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="BAF88955">
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
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            <end position="64"/>
        </location>
    </feature>
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        <location>
            <begin position="1"/>
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            <begin position="14"/>
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    </evidence>
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    </evidence>
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    </evidence>
    <sequence length="74" mass="8073" checksum="3102C3E29FF5501E" modified="2007-12-04" version="1">MGQTVKRKPAPPPERKTPPAPPPPEDGVVLTPEQLRRRRARSIAIASVLGFLVILFYVVTIVKLGPGVVLNRPL</sequence>
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    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172017.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3494"/>
    <dbReference type="EnsemblBacteria" id="BAF89492">
        <property type="protein sequence ID" value="BAF89492"/>
        <property type="gene ID" value="AZC_3494"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3494"/>
    <dbReference type="eggNOG" id="COG1573">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_044815_1_0_5"/>
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    <dbReference type="OrthoDB" id="1529383at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="135"/>
            <end position="285"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="35"/>
            <end position="90"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="68"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF89492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="297" mass="31239" checksum="FF273DBC13113984" modified="2007-12-04" version="1">MTSFAYEHFRDALAFYAEAGVDVAIGDEPVDRFAESAAEKARRGVGRSAPQTASAQPVNDSPAASPAPVRAPAAPRAPAPAAAGPGPMAAAQAPDQAVMAAREAAHTAASLDELRAMLEAFEGCPLKRTATRLVFADGNPAAKVMFVGEAPGRDEDVQGLPFVGRSGRLLDLMLGAIGLDRTKAYIANVIPWRPPGNRTPTPQETAICLPFIRRQVELANPDVLVCLGGPSAQALLSTTEGITKLRGRFMSYDTGSRTIKAIATFHPAYLLRTPLGKRLAWRDMLAVEAALNGETAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="6">MFS domain-containing protein</fullName>
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        <name evidence="7" type="ordered locus">AZC_3524</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
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        </source>
    </evidence>
    <sequence length="251" mass="27063" checksum="777D587A2F2A54FB" modified="2007-12-04" version="1">MALLEINNLHASINEKEILKGLDLKVNAGEVHAIMGPNGSGKSTLSYVLSGKPDYEVTEGSAVLDGVDLLELGADERAAAGLFLAFQYPVEVPGVATMTFLRTALNAQRKARGEDELSTPDFLRIVKEKAGFLGISQEMLRRGVNVGFSGGEKKRNEILQMALLEPKVAILDETDSGLDIDALKIVSEGVNALRSKDRAMVVITHYQRLLDHIVPDVVHVMHKGRIVRSGGKELALELEASGYAAYGQDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGA0</accession>
    <name>A8IGA0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_0062</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168593.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0062"/>
    <dbReference type="EnsemblBacteria" id="BAF86060">
        <property type="protein sequence ID" value="BAF86060"/>
        <property type="gene ID" value="AZC_0062"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0062"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="EMDTTIQ"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="324"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="411"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="373"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="674" mass="70965" checksum="4167DC1971BD4912" modified="2007-12-04" version="1">MAKFKVGIGLKLGIASVVLVLLSGGVIVSRQVAITEIREANAEVRQQQAVFDLLQEIHLLLSRIRVNTAEMRLSFANLDNENYLKQIKKDVASAKERLDKAIAVEPHEDDRASFRKLKALFDDMGTAAAAVYQTEADQLDAVDARPGIRMAARVAFANLTTQLTNVGDADAAREVEPLEAMLEQVNMASWSFLVEEDTKQLNIISVNEDSGHKALDAIQERLGGISMVASDLAAARKAFDDYIKSIRDGIAQAQARQKIVAEKAVPAMAATLKMLQEATDDGMKQSQEADAAATAALDSGMGQILIFSIIAILAAIGAALYSVFGIARPIQHVSAAMEEVSGGNLQAQIPYETRGDEVGDQARALAVFRDGLAEAEQLREQRALEERAAAERRKEEMHALADRFEAAVGAVVETVASAASELQGAAQTLTTTAEQTTNQASAVAAAANEATANVQMVAAAIEELSAAANEIGHRLSRSTEVAGRAVSEVDQTNGRMTELRGSADQIGNIVGMIDTIAGQTNLLALNATIESARAGEAGRGFAVVAQEVKELAGQTAKATADISSRIHGIQDSTGDVLSAITGIAQTIAEISEGTTAIAAAMEEQNATTAEVSRNIQQAASGTTQVTSNIAGVERAAQASSQAAQQVLSSATGLTRQADALRAEVQHFLSTVRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGC7</accession>
    <name>A8IGC7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0072</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A8IGC7"/>
    <dbReference type="STRING" id="438753.AZC_0072"/>
    <dbReference type="EnsemblBacteria" id="BAF86070">
        <property type="protein sequence ID" value="BAF86070"/>
        <property type="gene ID" value="AZC_0072"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0072"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030130_6_1_5"/>
    <dbReference type="OMA" id="GYPYWAW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000257">
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        <property type="entry name" value="NITRIL_CHT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="13"/>
            <end position="279"/>
        </location>
    </feature>
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        <location>
            <begin position="320"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="360" mass="39084" checksum="42592569550468CB" modified="2007-12-04" version="1">MEKSMSTPEKRIVRAAAVQIAPDLDDGKGTLERVLNAIAEAAGKGADFIVFPETFLPWYPYFSFIAPPVLTGGEHMRLYEHAVSVPGPVTDAISAAARRHAMVIVLGINERDHGSLYNAQLIFDADGTLKLKRRKITPTFHERMIWGQGDGAGLQVVETKVGRVGALACWEHYNPLARYALMAQHEEIHAAQFPGSMVGPIFADQMEVTIRHHALESGCFVVNATGWLTEDQIARISPDEKLRRALTGGCMTAIVNPEGSHLVPPLTSGEGMLVADLDMSLITKRKRMMDSVGHYARPELLSLHIDNRPAVPMQSVAAVSAPPAFGSPRDEADASDRRAHHPAADSGADDRVAVLRGPAR</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0088"/>
    <dbReference type="EnsemblBacteria" id="BAF86086">
        <property type="protein sequence ID" value="BAF86086"/>
        <property type="gene ID" value="AZC_0088"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0088"/>
    <dbReference type="eggNOG" id="ENOG5031E6R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097546_0_0_5"/>
    <dbReference type="OMA" id="VMATRSW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="249" mass="27159" checksum="1891DCD5447B53DB" modified="2007-12-04" version="1">MPAARHRDEPAHGADRDRRPSRTVPLPLPPLPPDTPMSTAVGPLRNRVDPFGDIAAHPARGLLMGNRGGRIHDPGTRTLTGRAWVSRQWICCALTFRDRRRAVMGEGYTELFFLDEVVAFAAGHRPCFQCRRVAADAFSAAWAKGEGRLPPGAGEMDRRLHAERLDGTRRRKHPRRLGDLPDGAVFAGEDGPVAVKDGRLLRFSFAGWAPLHGGPGLDATVPTLTPPSVLTALAAGYQPLWHPTAQHRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGJ7</accession>
    <name>A8IGJ7_AZOC5</name>
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        <recommendedName>
            <fullName evidence="12">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
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                <fullName evidence="12">Riboflavin kinase</fullName>
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            </recommendedName>
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                <fullName evidence="12">Flavokinase</fullName>
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        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="12">FMN adenylyltransferase</fullName>
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            <alternativeName>
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            <alternativeName>
                <fullName evidence="12">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">AZC_0098</name>
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    <organism evidence="14 15">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 12">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
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        </reaction>
    </comment>
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        <text evidence="4 12">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 12">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
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        <text evidence="12">Belongs to the ribF family.</text>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
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    </dbReference>
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        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF82114"/>
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    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
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    <keyword evidence="9 12" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
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        <source>
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            <dbReference type="ARBA" id="ARBA00022840"/>
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            <dbReference type="PIRNR" id="PIRNR004491"/>
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    </evidence>
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            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF86096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="328" mass="35098" checksum="5D62A274BDEBB5C3" modified="2007-12-04" version="1">MTSLPRAGRLPMPASQLSFQVVQGIRPLPEPLARPVLAIGNFDGVHRGHQAVIATARAMGARLGRPTLALTFEPHPRSFFQPSVPLFRLTPAREKLDALEATGLAGAIVLPFDGTLAALSAEAFVAEVLVGTFGIAGAAVGFDFHFGKARSGSPAFLKEQGAQHGFPVEVVEALLEADDTISSTAIRRALESGQVGHAAHMLGRHWSLRSVVIHGDKRGRDLGYPTANLALPEEIQLAFGIYAVKLTVDGIPHDAVASYGRRPTFDNGRALLEVHIFDFSGDLYGREVEVAFHGYLRPELKFSSVDELVRQMDADSRAARAILAASGS</sequence>
</entry>
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    <accession>A8IH67</accession>
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    <gene>
        <name evidence="2" type="ordered locus">AZC_0180</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86178">
        <property type="protein sequence ID" value="BAF86178"/>
        <property type="gene ID" value="AZC_0180"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0180"/>
    <dbReference type="eggNOG" id="COG1733">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111585_2_1_5"/>
    <dbReference type="OMA" id="WTWVVEN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="22"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="145" mass="16619" checksum="B7EF763F15D65654" modified="2007-12-04" version="1">MRDTGVNSLSREDVLKYSQTVCDGLRDDDDGVRREVLAHAGNRWSLGVIHTLGVYGQLRHAEIARRMHGVTQRMLTRTLRHLERDGLVIRHDFEETVPHVEYALSETGLELLVRMVPLWTWIVENADSFRAARAAFDRTHGTDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHB5</accession>
    <name>A8IHB5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATPase</fullName>
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    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0200</name>
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    <organism evidence="6 7">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
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        <property type="protein sequence ID" value="BAF86198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_0200"/>
    <dbReference type="EnsemblBacteria" id="BAF86198">
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        <property type="gene ID" value="AZC_0200"/>
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    </dbReference>
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    <dbReference type="OMA" id="VAQPGPW"/>
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    </dbReference>
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    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
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    <feature type="binding site" evidence="4">
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        </location>
        <ligand>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00005417"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50893"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="217" mass="23396" checksum="265F426C13038AAE" modified="2007-12-04" version="1">MLRDVSFSVKAGELVCILGPNGAGKTTTFRAISGLLPLSAGRVRIMGQDLATLRTEALSALGIGFVPEGRRLFAEISVRDNIRLGFEAQKGQGRFADRLEQMLDLFPRVRERINQRAGTLSGGEQAMVALARALIGAPKLVVMDEPSLGLSPKLIDEYFDTVAEINRRGTTVLLIEQNAETALSIAHRGIMLVKGRVVASGDAATLLSNDAVRHLYL</sequence>
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    <accession>A8IHE8</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAF89263"/>
        <property type="gene ID" value="AZC_3265"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_499369_0_0_5"/>
    <dbReference type="OMA" id="ETVHHHE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="Homeobox-like_sf"/>
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        <property type="entry name" value="HTH_TetR"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="HTHTETR"/>
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    </dbReference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
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        <location>
            <begin position="217"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="178"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="425"/>
            <end position="545"/>
        </location>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89263.1"/>
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    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="545" mass="55438" checksum="2FE9DCB0B296222A" modified="2007-12-04" version="1">MAPRKVTSSRATPARAARETKRSTPVEAAVPAPAPKAAGTRGAKAAAGKPAAPAKPAAPAKAPAAKAAATPAAAKTASAKPAAKPATSKAAKAAAPAAKAPSAKAAAAKPSAKAAEPTSKPAAKTTAKAAPKAAVSKAAASVKAKAPVPAPAKTEAKTAAAKPASTKPAPAKVATKKVATKTAVPVKAPAASAPARAKVAATAKAVQEALRSRLDPKVRRQMILDAAVAFFAEKGFEAQTRDLASRLGISQGLIFRYFSTKQALVNAVYEEVFVQRWSKDWEARLKDRDIPLEKRLQDFYGAYLEAVDASHWIRISLYAGLAGSEAFARYLENHGNRLLKIIQKEIHAHRGLPDRTGPDALDQELSWMLHSTILYALVRKHVNAQPVAEDRGALVALVVRTVLAGAAAGTAAALEAEKAAEKAARVAKPAEAPAAEAPKPAAPAAKGKARGAQPAAASAAPASRGRAKAAAAPKPVAAPKAPEVQAEPAKPAAAKAAPAKAAATKAAKPITKVGAKAKATEKAPTEAPALDRRRAAAPAPRRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
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    <organism evidence="8 9">
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Liu C.T."/>
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                <person name="Aono T."/>
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                <person name="Lee KB."/>
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    <sequence length="560" mass="61922" checksum="9A0E54D1689EACE2" modified="2007-12-04" version="1">MKLQIERPHLEAMVARFPGLSPLKDQLRFGDRVEVGFTQLSGDEIDFLQDLYRDGGPELATRSAQIATLQRAFNDKSVRFTSDALEAVLPAIAAYLVDGAIQGWLFTASVTSRPLPYVVTRIDYTAPSNDEAGRLFVELKANAKGALTSNTLRISSGDIAGKTVAEILAAKGFVKETPELIAAYEATEARYFEWRGRYGAQFTGTGTAFYTEDPNASHRDTDWSRKDVVVLSASGGPARLVNDESILTSRALTLDVPGDILGAYLRKAAKSNLYDAEDEVERQKAGIPAGLFSRIPIHPYILMFHLDLHHYLWVHVDDMKPYAYQPDLKHKLVLPEEQTDLIDILTAEMDLLMDDIVAGKSGGTTVLCAGPPGVGKTLTAEVYAEIIQRPLYRVHSGQLGLNAAAMEAALRETLTRAQRWGAVMLIDEADVYIKRREDDMTMNAVVGVFLRVLEYFNGLLFLTTNRIDDIDEAIVSRCIALIKFHTPDAAARRRIWDVMAEQFALDLDGQLIDTLVETFPDASGRDIKGLAKLVAKYCHHKQVPAGLPVFERCAVFRGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ10</accession>
    <name>A8IJ10_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-binding S4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0231</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168762.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0231"/>
    <dbReference type="EnsemblBacteria" id="BAF86229">
        <property type="protein sequence ID" value="BAF86229"/>
        <property type="gene ID" value="AZC_0231"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0231"/>
    <dbReference type="eggNOG" id="COG1188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_101003_3_1_5"/>
    <dbReference type="OMA" id="RWLCHAR"/>
    <dbReference type="OrthoDB" id="2006597at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="1">
        <location>
            <begin position="8"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="93" mass="10297" checksum="FF3C2A8345E3B67A" modified="2007-12-04" version="1">MAADEDRQRLDRWLWHARVVRTRAAAADLVRSGHVRLDGQRVTGAAHPVKLGQVLTVSLNAGVRVLRVRGFAERRGDATSVADLLDDITDESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJM1</accession>
    <name>A8IJM1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Pyruvate dehydrogenase E1 component</fullName>
            <ecNumber evidence="12">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">AZC_0327</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="12"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0327"/>
    <dbReference type="EnsemblBacteria" id="BAF86325">
        <property type="protein sequence ID" value="BAF86325"/>
        <property type="gene ID" value="AZC_0327"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0327"/>
    <dbReference type="eggNOG" id="COG2609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020309_0_0_5"/>
    <dbReference type="OMA" id="AWNRWNA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004660">
        <property type="entry name" value="PDH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
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    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transket_pyr" evidence="14">
        <location>
            <begin position="406"/>
            <end position="625"/>
        </location>
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    <feature type="binding site" evidence="13">
        <location>
            <position position="158"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    <feature type="binding site" evidence="13">
        <location>
            <position position="188"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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        </location>
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        </ligand>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_0329"/>
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        <property type="gene ID" value="AZC_0329"/>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    </feature>
    <feature type="domain" description="Ion_trans_2" evidence="2">
        <location>
            <begin position="62"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="149" mass="16280" checksum="4C8C3CE808B473CB" modified="2007-12-04" version="1">MPAELVYGILISLITVVIHSVASVFLVRALLVFTKRVRLRHAMRGLLLGMMLTGAILTFAHLVEVAVWAVAYVAVDGVVQDKDSYYLAFVNFTTLGYGDLLPAKPWRLLGPVTAANGMLLFGWSTALIFAVLTRLSEQLGVHHLSDKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="3 4" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="263" mass="29236" checksum="8BA03556FD99BEBB" modified="2007-12-04" version="1">MRALLAYSTQYFTDGIRPTEGAATGKGTGLVDQVADTPKLNVEPLGASSSLRALAYDALKRAITEMDIYGSNTDIRLDERQLSEDLGVSRTPIREAMTVLEQEGFVRSVPRRGIFVVRKTKRQLVEMITVWAALESMAARLAATRATAADLASLRRLFNDFEAERPAAHVPEYSKANIAFHQAIIRMGGSALIVDMTENLFLHMRAIRTVSIQQDNRSDVSMQEHMAIIDALEARDPERAERLVREHTMALAALVEKHGQFPE</sequence>
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                <person name="Aono T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
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                <person name="Toyazaki H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <name evidence="4" type="ordered locus">AZC_0565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0565"/>
    <dbReference type="EnsemblBacteria" id="BAF86563">
        <property type="protein sequence ID" value="BAF86563"/>
        <property type="gene ID" value="AZC_0565"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0565"/>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_0_1_5"/>
    <dbReference type="OMA" id="HDCHDHH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="3">
        <location>
            <begin position="293"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="388" mass="43100" checksum="9FC96E996370994F" modified="2007-12-04" version="1">MRRPYPEGVRSPLHARAAARTGDPMAETGSEKIPVTVLTGYLGAGKTTLLNRILSEPHGKKYAVIVNEFGEIGIDNDLVVGADEEVFEMNNGCICCTVRGDLIRIIDGLLRRKGQFDGIIVETTGLADPAPVAQTFFVDEEVGAKTKLDAVVTVADAKWLSDRLKDAPEAKNQIAFADVILLNKTDLVSADELAEVEGRIRGINPYARLYRTQKSQIEIEKVLNQGAFDLDRILALEPAFLEEGEDHDHDHTCGPDCGHDHHHHDHGHHHDHGHDHHHGHSHGGLKHYHDEEMQSVSFSTDKLLDPDKFFPWVQNVVATDGANILRSKGILAFKDDPDRFVFQGVHMILDGDHQRPWKPDEPQVSRIVFIGRHLPTEKLESGFLSCVA</sequence>
</entry>
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            <fullName evidence="3">Outer membrane protein Omp31</fullName>
        </submittedName>
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        <name evidence="3" type="ordered locus">AZC_3726</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3726"/>
    <dbReference type="EnsemblBacteria" id="BAF89724">
        <property type="protein sequence ID" value="BAF89724"/>
        <property type="gene ID" value="AZC_3726"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3726"/>
    <dbReference type="eggNOG" id="COG3637">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037100_0_1_5"/>
    <dbReference type="OMA" id="FITGAPN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724572" evidence="1">
        <location>
            <begin position="21"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="24"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="233" mass="24567" checksum="879D9F0F48E83916" modified="2007-12-04" version="1">MKRLLLSSAIAAAIIAPASAADLSTRYPVKAPVVAVVPVFSWTGFYIGANAGFGGDKYNYDFGAPGFGSATANSSGFFAGGQLGYNYQFANNVVLGLETDIQWSGIEGDTTLASGGSVANLNSSLDYFGTVRARVGYAFDRFLPYITGGFAYGESKTSITTITPTTLTFGEGSGTKTGWTLGGGVEYAFTNNWTFKTEYLYVDLDDSNYGVGAGAVNVDNKFHTVKAGINYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPL4</accession>
    <name>A8IPL4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellum-specific ATP synthase</fullName>
            <ecNumber evidence="4">7.1.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fliI</name>
        <name evidence="12" type="ordered locus">AZC_0646</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="4"/>
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        <property type="protein sequence ID" value="BAF86644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
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    <keyword evidence="10" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="161"/>
            <end position="344"/>
        </location>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
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            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
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        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
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        <subcellularLocation>
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    </dbReference>
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    </evidence>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF86721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF86721">
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        <property type="component" value="Chromosome"/>
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        <location>
            <begin position="73"/>
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        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF86721.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="398" mass="42526" checksum="C673196B92251CA2" modified="2007-12-04" version="1">MLPSGSAAKECRAAAERGRAMRRENGLLRRLKTATRWLSRAPVRTAHRFEAEARADVAAFTVHGRRAQVALRVTLGVLVAIAIAHALGLEMPVWAAISVVRVFQNDRTATVMRGLERVAGTIGGCAVAYAILKISGAHAWVYMATGLACAAAVYAQAVTRYSYAFVLVGFTVPLMTYHAVVSPEPMTQVILMRGMEVMVGVCVAWALDFLTSPARPKAKPKPLYAGMDAIFMGHALTVGIAVTLVPVVWTVLHLPGFEQTPITAFIVVGAAREGIGWKSLNRCVGCALGAAFGFLGVLTLDGSLLTWALFVFAGLFVFTQIGFGGSVVAYTGIQAAIAFLLVVVQEPIPHLDLDAGVGRMWGVMGGIALVMLVGLATWPIRRRITERLQPRASHEAAH</sequence>
</entry>
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    <accession>A8IQB2</accession>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
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                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        </source>
    </evidence>
    <sequence length="298" mass="32615" checksum="ECE38FA05BA194CC" modified="2007-12-04" version="1">MTQQTIQRCAIAEGTDMKLATFKIGARPTWGVIAGDEALDVGAVLRDRYGSLKAVLAADALSQVEAALPQAARHPLSEITWLPVIPDSNKVLCIGLNYEMHRLETGRAVVEHPTVFTRFADSQIGHLAHIIRPRVSQHLDFEGELAIIIGKPGRYITRENAWSHIAGYSCYNEGSIRDFQRHTHQFAPGKNFPGTGAFGPWMMTPDEAGDITTMKLETRLNGTVVQEALISQMIFDIPCQIEYCSTFTNLEPGDVIVTGTPGGVGAKRTPPLWMKPGDIVEVEIDRVGILRNGVADEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQL9</accession>
    <name>A8IQL9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ordered locus">AZC_0798</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169329.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0798"/>
    <dbReference type="EnsemblBacteria" id="BAF86796">
        <property type="protein sequence ID" value="BAF86796"/>
        <property type="gene ID" value="AZC_0798"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0798"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_2_0_5"/>
    <dbReference type="OMA" id="VCIQHEI"/>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="172" mass="19144" checksum="D4C05F554064D5BA" modified="2007-12-04" version="1">MAILPILIIPEPQLRQISAPVPRIDKEIEKLAADMLETMYDAPGIGLAAIQVGVHKRVITIDIAREDAPKNPIVLINPEVVSASEETSFYNEGCLSIPEYYEEVERPAQVTVRYQDLKGATHEIAADGLLATCLQHEIDHLNGVLFIDHLSRLKRERVIKKFTKAARREAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQR0</accession>
    <name>A8IQR0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptide ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_0810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169341.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0810"/>
    <dbReference type="EnsemblBacteria" id="BAF86808">
        <property type="protein sequence ID" value="BAF86808"/>
        <property type="gene ID" value="AZC_0810"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0810"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_1_5"/>
    <dbReference type="OMA" id="YMIIMEA"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="8">
        <location>
            <begin position="103"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="305" mass="32280" checksum="ACFAC5D4C60492E9" modified="2007-12-04" version="1">MTDLAPSATEASRLDAAPPRRSPSMALLRRSLRHGGLMAGAVILFLIIALALLAPLIAPHDPYAQDLSRRMMPPVWQAKGTWEHILGTDKLGRDYLSRLLFGARISLLIGAVTVLISGTIGTLLGVCAGYFGGRVDAVLSYIVTTRLALPVVLVALASAALVGSSLQGVIIVLGLLLWDRFAVVTRSATQQIAGSDYIGAAKAIGCSTPRIILSEILPNILNPLIVVATLEMAHAILLEAALSFLGLGVQPPLPSWGLMIAEGKQYMFFSPWVIAVPATALVFLVLAINLLGDGLRDVTAPENRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQE9</accession>
    <name>A8HQE9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="10">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Glycyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="10">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">glyS</name>
        <name evidence="12" type="ordered locus">AZC_1032</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169563.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1032"/>
    <dbReference type="EnsemblBacteria" id="BAF87030">
        <property type="protein sequence ID" value="BAF87030"/>
        <property type="gene ID" value="AZC_1032"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1032"/>
    <dbReference type="eggNOG" id="COG0751">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007220_2_1_5"/>
    <dbReference type="OMA" id="LPIPKRM"/>
    <dbReference type="OrthoDB" id="213210at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01045">
        <property type="entry name" value="TRNASYNTHGB"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="631"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF87030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="744" mass="82092" checksum="743684AF7037D47A" modified="2007-12-04" version="1">MPDLLLELFSEEIPARMQAQAADTLRKLVTDALVERGLLYEGAKAFVTPRRLALAVHGLPGRQADSREERKGPRMGAPEGAIQGFLKSAGLASIDQAKIESDPKKGEFYVAVIERPGKATTEVIAEIVPEIVRTFPWPKSMRWGTGTMRWVRPLHSIVCTFGTEVEDPEVVRFEVEGIVSGDVTRGHRFLAPEPFAVRRLEDWMAKLEAAKVVADRDRRKAIILNDAKDLALVHGLELVEDEGLLEEVCGLVEWPVTLMGSFEERFLDIPDEVIRATIRANQKCFVLRDPRTGRLANRFILVSNIAATDGGAAIVAGNERVIRARLSDAKFFWDTDRRTPMADRMSKFDAITFHEKLGSQGARINRIVALAREIAPRVGADVDLTEQAARLAKADLLTEVVGEFPELQGLMGRYYAQHEKLPPEVAAACEEHYKPQGPSDRVPTAPVSIAVALADKLDTLVGFWAIDEKPTGSKDPYALRRAALGVIRIILDNNLRLPLRPLLVSASRTILGEEHFERHPHDVFRLETIADKVVSDLLQGLARRLANLPADADVESAERVEGMTLSGDLADDLLAFFGDRLKVHLRDRGARHDLVDAVFALPGQDDLLLVDRRVAALAAFLETEDGRTLLAGYRRAVNILRIEEKKDGVAYKGPSEAKLLKEPAEEHLAAAIETVKRQVADAVAREDFAAAMGALAHLRGPVDAFFEGVTVNAPEAALRINRLKLLDEIRSATRGIADFDRIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQH7</accession>
    <name>A8HQH7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nitrogenase iron-molybdenum cofactor biosynthesis protein NifN</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">nifN</name>
        <name evidence="8" type="ordered locus">AZC_1037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the NifD/NifK/NifE/NifN family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169568.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="SMR" id="A8HQH7"/>
    <dbReference type="STRING" id="438753.AZC_1037"/>
    <dbReference type="EnsemblBacteria" id="BAF87035">
        <property type="protein sequence ID" value="BAF87035"/>
        <property type="gene ID" value="AZC_1037"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1037"/>
    <dbReference type="eggNOG" id="COG2710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025876_2_0_5"/>
    <dbReference type="OMA" id="HFYFGGK"/>
    <dbReference type="OrthoDB" id="397330at2"/>
    <dbReference type="UniPathway" id="UPA00782"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016163">
        <property type="term" value="F:nitrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065003">
        <property type="term" value="P:protein-containing complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01966">
        <property type="entry name" value="Nitrogenase_NifN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000510">
        <property type="entry name" value="Nase/OxRdtase_comp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000318">
        <property type="entry name" value="Nase_comp1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005975">
        <property type="entry name" value="Nase_Mo-Fe_CF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00148">
        <property type="entry name" value="Oxidored_nitro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01285">
        <property type="entry name" value="nifN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00699">
        <property type="entry name" value="NITROGENASE_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_nitro" evidence="7">
        <location>
            <begin position="19"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="455" mass="49899" checksum="66297D5CBBDDA9CC" modified="2007-12-04" version="1">MATVVHSRKACVVNPLKMSQPIGGALAFMGLRGAMPLLHGSQGCTSFGLVLFVRHFKEAIPMQTTAMSEVATVLGGYENVEQAVLNIHKRTKPEIIGICSTGVTETKGDDVEGYLKLIREKHPEVADLPMIYVSTPDFKDAFQDGWEKTVTRMVEVLVEVPDPAKRNAKRVNVLPGSHLTPGDLDELRTIIEDFGLIPSFLPDLAGSLDGHIPDEFTPTTIGGIGVDEIAAMGEAGWTIAIGAQMRRAAEAMEKKTGVPFRLFERLCGLEANDEFIMFLSQISGRPVPRKYRRQRGQLVDAMLDAHFHIGGRRLAIGAEPDLLFDMSSVLHEMGAHVTAAVTTTHSPVLERVHTDEVLIGDLEDLERLAKERECDLLITHSHGRQAASRLNIPFYRAGIPMFDRLGAGHQLSVGYRGTRTTLFTIANLLISDHEANHDATPDTWRTDGTHAAPMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQQ9</accession>
    <name>A8HQQ9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdopterin-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1054</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169585.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1054"/>
    <dbReference type="EnsemblBacteria" id="BAF87052">
        <property type="protein sequence ID" value="BAF87052"/>
        <property type="gene ID" value="AZC_1054"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1054"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    </dbReference>
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            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87120.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="193" mass="20103" checksum="7D279F96507BB009" modified="2007-12-04" version="1">MWSLSTACGLARRFAIRSLGLSRGEADANRLSRRALHRAQPVGGPCYAIIGCQRSCRSVVTDRVGWITASGFGRARLIAPVFSRSACRSCPMRFVPRLGRLSVALLALAPSLALPALAQTKPTAADVACAAMGPGFKRISGSDTCMQLSGSVEMTAARGTAPSNAPNQGFTNTPTAAASGTPAPAGDPWKQMR</sequence>
</entry>
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    <accession>A8HRI4</accession>
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        </alternativeName>
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        <name evidence="11" type="primary">ilvA</name>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    </reference>
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        <text evidence="10 11">Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.</text>
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    <comment type="catalytic activity">
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            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
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    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
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    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
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        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="ilvA_2Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="5 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="337"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="432"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00025527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF87191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="513" mass="56047" checksum="C27A43CFB1DC6BEC" modified="2007-12-04" version="1">MQRSSGSTSVEDYIRKILAARVYDVAIESPLDPMRRLSGRLGSPVFLKREDLQPVFSFKLRGAYNKMVGLDEEARAHGVICASAGNHAQGVALAAKALGVKATIVMPRTTPDIKVQAVNANGGDAVLHGDTFDEAYAHAKTLEAQTGAVFIHPYDDPQVIAGQGTIGMELMRQHPDPLEAIFVQIGGGGLAAGVAAYVKFLRPDVKVIGVEPEDAASMTAALAADERVKLNQVGLFADGVAVRQAGEETFRLCRQLLDGMITVTTDEICAAMKDIFEDTRAIPEPSGAVSLAGLKKYVEQHGPSQRGLIAINSGANLNFDRLRHIAERAELGERREALFAVSIPEKPGSYRHFIRVLGARAITEFNYRYAPAGEAQIFVGVQLTGGEAERKAVADLLRAEGYGVIDMSDNEMAKLHVRYMVGGRTPDLPNEMVYRFQFPERPGALLKFLESMAQTWNITMFHYRNHGADYGRVLAGIDVPPQERAEFAERLTALDYPCWDETDNPAYRLFLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRQ2</accession>
    <name>A8HRQ2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4077</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172597.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4077"/>
    <dbReference type="EnsemblBacteria" id="BAF90075">
        <property type="protein sequence ID" value="BAF90075"/>
        <property type="gene ID" value="AZC_4077"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4077"/>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_2_0_5"/>
    <dbReference type="OMA" id="WRAVKDN"/>
    <dbReference type="OrthoDB" id="1456257at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="327" mass="35524" checksum="8E97FBE2337E23D6" modified="2007-12-04" version="1">MSAAPSFTARRTRQLLLALVIFALVALLPFGVKDVYTLNVLILLLLYAGLSQSWNILGGYCGQLSLGHALYFGIGAYTSTLLYTKFGVLPWFGMALGGVIAALIAMGIGHACFRLAGHYYVIATIVIAEIGLLLFHNWDWAGAATGIELPIGRDSWLTFQFARDKLPYFYFVLVFAAVVWLVTWKIENSKWGYWWRAVKDNPEAAESLGVVVFNSKMMAAAVSAFFTAVGGSFYAQFLGYIDPESVMTFQFSLLMALPAVLGGIGTLWGPVLGAAILIPLTELTRTYMGGSGKGIDLIVYGCLIMAIALARPDGLVGLFQRRKRSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRW5</accession>
    <name>A8HRW5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative branched-chain amino acid transport system permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Liu CT."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="1 2" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="16" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <text evidence="9">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.</text>
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        <text evidence="10">Homohexamer. The oligomerization is ATP-dependent.</text>
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    <comment type="subunit">
        <text evidence="13">Homohexamer; The oligomerization is ATP-dependent.</text>
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        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
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        <text evidence="2 12">Belongs to the ClpA/ClpB family.</text>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="14">
        <location>
            <begin position="3"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="413"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAF90198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="879" mass="96712" checksum="1B2A9953B73E6DE4" modified="2007-12-04" version="1">MNFEIYTERARGFVQSAQSYAVREGHQQFVPEHLLKVLLDDPEGLCAGLVSRAGGNLQLVRDETEAAVRKLPKVQGGSGQVYLSQGLARVFDAAEQAAKKAGDGYVTVERLLLALTIEKETEAGKILARGGVTPQALNTAIEALRKGRTADTATAENAYDALKKYARDLTQAARDGKLDPVIGRDEEIRRTIQVLARRTKNNPVLIGEPGVGKTAIVEGLARRIVDGDVPESLKNKSLLALDMGALIAGAKYRGEFEERLKGILQEVTAAEGGIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLDEYRKHVEKDAALARRFQPVFVSEPTVEDTVSILRGLKEKYELHHGVRITDSALVAAATLSNRYITDRFLPDKAIDLVDEAGSRLRMQVDSKPEELDSLDRDIVRLKIEQEALKKETDVASQDRLKRLEKELADLEEKSDVLTSKWKAEKDKLGEATDVKAKLDQARADLAIAQRQGEYQKAGELTYAVIPGLEKRLAELEASGQSGEMVKESVTPDHIAGVVSRWTGVPVDKMLEGERDKLLRMEQELAKRVIGQSEAVAAVSTAVRRARAGLQDPNRPIGSFLFIGPTGVGKTELTKALASFLFDDETAMVRLDMSEYMEKHSVSRLIGAPPGYVGYEEGGALTEAVRRRPYQVVLFDEVEKAHQDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNLGAEYLADPRQPVGFGIPGHDGEKVVSDEEAYELVMQAVRRHFRPEFINRIDEIVMFHRLRKDQMGGIVEIQLKRLAKLLEDRKITLDLTPEARAFLADKGYDPAYGARPLKRTIQKLVQDPLAQQILSGEVLDGSRVHIGLENGHLTFRGEAAPVDQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSV7</accession>
    <name>A8HSV7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172743.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4223"/>
    <dbReference type="EnsemblBacteria" id="BAF90221">
        <property type="protein sequence ID" value="BAF90221"/>
        <property type="gene ID" value="AZC_4223"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4223"/>
    <dbReference type="eggNOG" id="COG2208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013743_0_0_5"/>
    <dbReference type="OMA" id="ILTDMTH"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="289"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="682" mass="74646" checksum="1A7FF300D6A7C768" modified="2007-12-04" version="1">MLLRTRITLLVAAGFLVLLGCFGALFYMRDRMDAERLSAVVIQGQQALWRESVEVEASALDKSLDAFSASPELRAALLAGDRSAVVAGLNKLDVFSSGTPLIFEVLSEDREALLVQGTPQDRGLLDAGSMDRVLTGERITGLRQISADQILVVAARRISLPNGDNVILVLGRDARSAVTRFAGSIHAASSLLTLRGQLAAATDPNLWRQANLAISPRQALRDEIALSGRIYSVTSVPVGDITNSTVGALVSMVDNTESITYARRVRAIGITIGLGLALLGIVGLNAFLWYSFRPLERAIDVLQALSRGDTSVSLNYAGRDEIGRIAKALVSFRANVQELAETRRQRERVRRRQEMVISAELKALADAIDPQDRDQVLSLLTADTDRGEDELRRVARVLHDLSRRIVEQHTRLSSMVVELREALVTKTKLAGLQQELEIAAQVQLAILPRAFPPHPRIGVHGHMTPAREVGGDFYDYFLIDDSTLGFVVADVSGKGVPAALFMAISRTLLRSTAMFERSPAVSVRRLNDLLALENEQMLFVTLFYGVINLDTGKVSYVNAGHNLPYKITQANEVSVVPSTKGMAVAVMEGFVYEEGELYLSAGDTLFLYTDGVPEAFDIDEAPYGDERLAELLKEGAAHWPVPEMPERVLQSVRAFERGAPQADDITCLTLRYFGGNTRRHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTP4</accession>
    <name>A8HTP4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0858</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172799.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4279"/>
    <dbReference type="EnsemblBacteria" id="BAF90277">
        <property type="protein sequence ID" value="BAF90277"/>
        <property type="gene ID" value="AZC_4279"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4279"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_37_0_5"/>
    <dbReference type="OMA" id="TNNNRVD"/>
    <dbReference type="OrthoDB" id="846433at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="294" mass="31780" checksum="A70EFB3BCCD49DDB" modified="2007-12-04" version="1">MDRPQLPLNALRAFEAAARHLNITRAAMELCVGQAAVSHQIKALETRLGAQLFRRLPRGLALTDEGAALLPLVRDAFDRIGATLDRFMDGRLREVLTVGVVGTFAVGWLLPRLPDFAAAHPGIDLRVLTNNNRVDLAGEGLDCAIRFGDGSWHGVAAAELMPAPLSPLCGPALAARLSRPADLAHVPLLRSYRTEEWSRWFAAAGTPALTFRGPVFDSSPLMASAAAAGHGVALLPVRMFSADLVAERLVQPFPIAIDAGRYWLTRLFSRPETPAMAAFRRWIETAVATDESGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVP9</accession>
    <name>A8HVP9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mg chelatase-related protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172862.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4342"/>
    <dbReference type="EnsemblBacteria" id="BAF90340">
        <property type="protein sequence ID" value="BAF90340"/>
        <property type="gene ID" value="AZC_4342"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4342"/>
    <dbReference type="eggNOG" id="COG0606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026145_1_1_5"/>
    <dbReference type="OMA" id="STNPCPC"/>
    <dbReference type="OrthoDB" id="581802at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="209"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="510" mass="52868" checksum="B506252DB6F7F312" modified="2007-12-04" version="1">MIQRVATVAFEGVEARPVDVQVHVAAGLPAFTIVGLPDKAVTEAKERVRAALIASGLALPARRITVNLAPADLPKEGSHYDLPIALGLMAAIGAIPSDALNGFTVVGELGLDGSIASVAGVLPAAIGANARGHGLICPAACGAEAAWASPEMEILAPSSLIQLANHVTGRQVLARPDPRLRDARSGGLDLRDVKGQETAKRALEVAAAGGHNLLYVGPPGSGKSMLAQRLPSILPPLVPGEMLAVSMIASVAGNIEDGALIDRRPFRAPHHSASMAAMVGGGLKARPGEVSLAHLGVLFLDELPEFSAQVLDSLRQPLESGEVMIARANNRVSYPARFQLVAAMNPCKCGRAGEPGYTCKRGPRCAEEYQARLSGPFLDRIDIHLEVPAVSAADLVLPAPAEGSAEVAARVAAARALQRERYAALGRPDIATNAEATGTLLDEVARPDAAGAALLRDAADAMRLSARGYHRVLKVARTLADLSGAETLGRAHLAEALAYRALADRPRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8HW22</accession>
    <name>A8HW22_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent haemoglobin/transferrin/lactoferrin receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_4384</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4384"/>
    <dbReference type="EnsemblBacteria" id="BAF90382">
        <property type="protein sequence ID" value="BAF90382"/>
        <property type="gene ID" value="AZC_4384"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4384"/>
    <dbReference type="eggNOG" id="COG4771">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_19_3_5"/>
    <dbReference type="OMA" id="AWEVGFN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011276">
        <property type="entry name" value="TonB_haem/Hb_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010949">
        <property type="entry name" value="TonB_Hb/transfer/lactofer_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01785">
        <property type="entry name" value="TonB-hemin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01786">
        <property type="entry name" value="TonB-hemlactrns"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="105"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="290"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF90382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="764" mass="80779" checksum="17D9EC756E178677" modified="2007-12-04" version="1">MGRLTARASARSVSAVSLCRKGSGPFRRAAARGLSSVAGAALVAGGLAWAGPAAAQSATTAPAGSSSASWPASSQPAMTTGPGGEIALDAITVVATYTPISTINALAGVSTVRLDQLQEYLPDRTADVFWGMPGVTAIQNGNSTQTSVNIRGLQDFGRVAVIVDGARQNFTQLGHANSAGSFFVEPGLLAGVDVIRGPVSNIYGSGAIGGVVTMRTKDANDILKPGQTWGVEGTGEMGSNGPMGFGSAFGAARVGPNIDLFWGGTYRDQGNYSDGNGNEVPGTANTTWTGIAKATIRPADFHEIKLSALNYDSSYTTSSASVITTPTTSQYGTDITNRTVSASYNYSNPDNNLFDWRSTVYWNQVQQDQVKVAGTNSTVTGNVGNPRSFTIDTVGFDANNTTRFALGPVRNAVTVGGDYFHDDVSNIDRYGFGDGYNPSGTRGVGGAFVQWQANYSTWLEAIGAVRYDSYTLNGNGVSNSGDRFSPKLTIGLTPLPWFTVYGTYAEGYRAPAVTETLVAGAHPPAMPIVTCPDGSIGTFCFLPNANLQPEVGKNKEIGVNLKFDDLLTKGDKLRLKADVYRNDVSDFIELVQFGRTRFGTTAYAQYQNIASARLQGFELESMYDARLWFAGISATVSEGKDTSDNQPLSSIQPDNVATTIGLRSPDQTLSLSLRWQWVAAVTAADLPTNSVYAPTSSFNLVNVYLGYQPSENVRMSLSAENLLNEQYTQYQQFLPSAGLTVRGAVTIRFGGGEVASSKPAALTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWD4</accession>
    <name>A8HWD4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fkbM</name>
        <name evidence="2" type="ordered locus">AZC_4419</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4419"/>
    <dbReference type="EnsemblBacteria" id="BAF90417">
        <property type="protein sequence ID" value="BAF90417"/>
        <property type="gene ID" value="AZC_4419"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4419"/>
    <dbReference type="eggNOG" id="COG2242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_074577_2_1_5"/>
    <dbReference type="OMA" id="VIFEMNC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="46"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="241" mass="25561" checksum="B5CD9B24286EA250" modified="2007-12-04" version="1">MPGGGRLRVPADFRYTSVSAFLLRDQVEPELRYIQKFVRPGDIFIDVGANIGLFTVKMAPTAGRVVAVEPGSTAGSLLADNVALNHFSNVAIVRKALSDSVGVASLHHNPLGNDPQAFSLVSDGSDAETEQVPITTLDVMVTEQRLARVDCIKIDVEGAEGQVIAGGMDTLRAYHPAVIFEMNCPTLLKAGGDPAAAWNALQGLGYRFFRLAEDGALLPLASRPGAFCNVVALHPEGRPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWF3</accession>
    <name>A8HWF3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4425"/>
    <dbReference type="EnsemblBacteria" id="BAF90423">
        <property type="protein sequence ID" value="BAF90423"/>
        <property type="gene ID" value="AZC_4425"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4425"/>
    <dbReference type="eggNOG" id="ENOG5033J2F">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_137196_0_0_5"/>
    <dbReference type="OMA" id="PARHEIW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="164" mass="17820" checksum="36E7F0971BB02152" modified="2007-12-04" version="1">MPKSRGTASAGHTAPVARTAGGRMKHALAKVASALAGGALLAASLAEPAGAQLQGMPRSDLPAQGSTDPEIDPFPFDPRLEIRSYVASRLPTEWWAKEPIYNLGLFSVEIHPPAAWRGNPTSAMMRLCPPARHEIWRHLQKIELRPFYHDAPWPAFTCRPGTVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWG6</accession>
    <name>A8HWG6_AZOC5</name>
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        <submittedName>
            <fullName evidence="4">Outer membrane autotransporter barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_4429</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4429"/>
    <dbReference type="EnsemblBacteria" id="BAF90427">
        <property type="protein sequence ID" value="BAF90427"/>
        <property type="gene ID" value="AZC_4429"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4429"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_273280_0_0_5"/>
    <dbReference type="OMA" id="DWTNPAN"/>
    <dbReference type="OrthoDB" id="1713183at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013425">
        <property type="entry name" value="Autotrns_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12951">
        <property type="entry name" value="PATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02601">
        <property type="entry name" value="autotrns_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723117" evidence="2">
        <location>
            <begin position="26"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="3">
        <location>
            <begin position="866"/>
            <end position="1153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1153" mass="118608" checksum="1A2269C10715262D" modified="2007-12-04" version="1">MEGEVRRLSIALFSSTFLLPAYALAQQVPTSPPVNFVNSTTPATGTTLTKVLDAYTDLMVNHPEVMVKNYQTVVSMTQNRTAAQTEAAIRADRTSQAYNVMNGLGPLTNFYLTGAGASTSGTAPQSLTPTTYVTGTLADYQRDINYLSNASAGSQTFGNGTKTPLASAVNFIDNIARANASTEPAKRTFDRYQGATPAINPLDSRYQNYSAATKTGLTTADTASFVVPGYLSQFTVPAAYGTVDNWVKGFTVTAAMVAANGGQPISVPNVGSYDAAGNFTPTLFNVGDYVPGIGTSPRPFRVTSAVNIPTLLYQRINGTNPYADGGFPSGHTNSGYLQSYAVAFLVPQRGQEMLMAASELGNNRILAGMHSPLDVIGGRMESSAIVATNIYGALYDSTGNRLDWTNPANASAYAVYQAYNDTQNYLAASCNAVSVQACIQQAQAAGFGATDPLAYSAANKALYTARLTYGLPVIGPVKAMTAADVPVQAQVLLLTRFPYLSDAQRTEILATTALPSGYAQLSGNTYDGWGQLNLYAAFDGYGAFNSQVNVTMDASLGGYNAADAWRNDITGTGGLTKGGTGQLTLSGNNTYTGPTVINGGYLIVNGSIVSPTTVNSGGTLGGTGRVGNVTVNGGGTLMPGTLGSAGTLTVNGNLAMAANSKLLITATPTATSNVQVNGTATLQGGTVQVGATGTFLPFTQVALISATGGVNGQFAGVTTSGSNLTSALSYDAKTVTLTMNRTDVNYATVAATANQRSVGAALNAAAPSAATAAAGTLVNGVFLSNQASAGLGQAALDSVSGAGLTASQGAALQATSAFTSNIQDQQDTWFTYGRTAPAASASSPALNYAAAPKTKFPPVKAVPAPAPEQRWNVWGGAFGSTTSIDSAPGLTGQSSTTWGGLVGLDYRVQPDWLVGIALGGSTSQFSTTSLNTSGTVDGAHISLYTTYALPSDSYVRGVFTFSGFSNDVKRVAGGVGALAAENEKGSFDSYEARVRGEIGKRFGFGAFGVTPFAAMEFATLNSSAFNEVNSQTGTVGNLSLQVNGQSTQSAPLFLGTRFDAAMPMDGGRALRADATLAYVHDFYSDRSLTNSFVALPGSSFLVQGVSPSADAVQTKVGLEFGVTANTAVFANFNGLFSDNSTSYAGSGGLKVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXT6</accession>
    <name>A8HXT6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate/bisphosphoglycerate mutase</fullName>
        </submittedName>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170137.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HYF4"/>
    <dbReference type="SMR" id="A8HYF4"/>
    <dbReference type="STRING" id="438753.AZC_1609"/>
    <dbReference type="EnsemblBacteria" id="BAF87607">
        <property type="protein sequence ID" value="BAF87607"/>
        <property type="gene ID" value="AZC_1609"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1609"/>
    <dbReference type="eggNOG" id="COG1219">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014218_8_2_5"/>
    <dbReference type="OMA" id="HYKRVQA"/>
    <dbReference type="OrthoDB" id="718259at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000071621" description="ATP-dependent Clp protease ATP-binding subunit ClpX">
        <location>
            <begin position="1"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="ClpX-type ZB" evidence="2">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="119"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <sequence length="422" mass="46140" checksum="5386D547D242D5E3" modified="2007-12-04" version="1">MSKTGGSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGIPTPKEIRKVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKHGDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDKIISSRSKGGTSIGFGAKVAPVEERRPGELFREVEPEDLLKYGLIPEFIGRLPVLATLNDLDEAALKQILAEPKNALVKQYQRLFEMENVDLTIHEEALGAIARKAIERKTGARGLRSIMEGILLDTMFDLPGLEGVEEVVISKEVVEQNARPLYIYADRVGDAGASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYS0</accession>
    <name>A8HYS0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="5">RF MTase</shortName>
            <ecNumber evidence="5">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hemK</name>
        <name evidence="5" type="synonym">prmC</name>
        <name evidence="8" type="ordered locus">AZC_4493</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173012.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4493"/>
    <dbReference type="EnsemblBacteria" id="BAF90491">
        <property type="protein sequence ID" value="BAF90491"/>
        <property type="gene ID" value="AZC_4493"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4493"/>
    <dbReference type="eggNOG" id="COG2890">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018398_3_1_5"/>
    <dbReference type="OMA" id="FDARYWE"/>
    <dbReference type="OrthoDB" id="1816476at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="7">
        <location>
            <begin position="11"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltranfer_dom" evidence="6">
        <location>
            <begin position="120"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="126"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="192"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="287" mass="29253" checksum="99D2491D80722783" modified="2007-12-04" version="1">MTAPPLTLGGLRRQLATRFSAAGIDSPDLDASLLIAHALGLEPGDVRLRGADPLAPDALPRIEALAAQRLSGVPVARLVGEKEFWSLSFSLSPETLVPRPDTETVVEAALMTVTDRTAPLHILDLGTGSGAILAALLVELPAAVGIGVDQSEGAARTARDNLARAGLQGRGTVIVGDWASALGGGFDLVVSNPPYIPSIDIVGLAIEVRENDPLAALDGGADGLSSYRIIAAEAPRLLKAGGHLVLELGIGQEAEVAALAGAAGLAITGPARRDLGGIPRALVARRS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0I5</accession>
    <name>NRDR_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nrdR</name>
        <name type="ordered locus">AZC_1262</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NrdR family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169793.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I0I5"/>
    <dbReference type="SMR" id="A8I0I5"/>
    <dbReference type="STRING" id="438753.AZC_1262"/>
    <dbReference type="EnsemblBacteria" id="BAF87260">
        <property type="protein sequence ID" value="BAF87260"/>
        <property type="gene ID" value="AZC_1262"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1262"/>
    <dbReference type="eggNOG" id="COG1327">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_108412_0_1_5"/>
    <dbReference type="OMA" id="YRFTTYE"/>
    <dbReference type="OrthoDB" id="1551627at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0678">Repressor</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_1000080709" description="Transcriptional repressor NrdR">
        <location>
            <begin position="1"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-cone" evidence="1">
        <location>
            <begin position="49"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="zinc finger region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <sequence length="173" mass="19989" checksum="02BF6B539AB4D527" modified="2007-12-04" version="1">MRCPYCGSLDTQVKDSRPTEDNTAIRRRRVCPDCGGRFTTFERVQLRELMVVKRSGRRVPFDRDKLARSVEIALRKRPVETERVERMLSGLVRQLESLGDTEITSETIGEMVMEGLKQIDDVAYVRFASVYRNFREARDFESLLDELQLGERKAEALAKLKRADRTASESEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0U6</accession>
    <name>A8I0U6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysR</name>
        <name evidence="2" type="ordered locus">AZC_1298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1298"/>
    <dbReference type="EnsemblBacteria" id="BAF87296">
        <property type="protein sequence ID" value="BAF87296"/>
        <property type="gene ID" value="AZC_1298"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1298"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2033300_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysR_substrate" evidence="1">
        <location>
            <begin position="8"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="121" mass="12886" checksum="7548A4E1F7E5ED7E" modified="2007-12-04" version="1">MREFPLQSSGQALRWSFKLGDRTQEMITDAAIVTDVSDAVAAVLAAGGGIGISPTFVAAPYVARGLLVPLLQGYFAPRSAITALWPEGRRASPNVKAFLGFLTDIFPRDPPWDAVLRANGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0Y6</accession>
    <name>A8I0Y6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1312</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169840.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1312"/>
    <dbReference type="EnsemblBacteria" id="BAF87310">
        <property type="protein sequence ID" value="BAF87310"/>
        <property type="gene ID" value="AZC_1312"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1312"/>
    <dbReference type="eggNOG" id="ENOG502Z8PE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1538849_0_0_5"/>
    <dbReference type="OMA" id="DHNRRET"/>
    <dbReference type="OrthoDB" id="1317064at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="182" mass="20175" checksum="A3C96FFD48D64EEC" modified="2007-12-04" version="1">MKVLTDKILSESAYSAEIDVPFEKVDIADWLFTLPEAEYLRCCPPDHIGSGVTTKDDGRRMVINVEMIGTGLVIQHYVAEEATPAYCRMNSISDVFTPVGRTQVNVIWELIAEAIEGGRTRYTNRVTSHPTDVFMDFLAAHKQSFEQAAIARQEAGGDHNRRETPLFAASIGRRAMAKAAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1B4</accession>
    <name>A8I1B4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyruvate dehydrogenase [ubiquinone]</fullName>
            <ecNumber evidence="2">1.2.5.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Pyruvate oxidase</fullName>
            <shortName evidence="2">POX</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Pyruvate:ubiquinone-8 oxidoreductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">poxB</name>
        <name evidence="7" type="ordered locus">AZC_1355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2</text>
            <dbReference type="Rhea" id="RHEA:27405"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="EC" id="1.2.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="2">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.2.5.1" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169883.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1355"/>
    <dbReference type="EnsemblBacteria" id="BAF87353">
        <property type="protein sequence ID" value="BAF87353"/>
        <property type="gene ID" value="AZC_1355"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1355"/>
    <dbReference type="eggNOG" id="COG0028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013748_3_0_5"/>
    <dbReference type="OMA" id="YEATHEC"/>
    <dbReference type="OrthoDB" id="351701at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052737">
        <property type="term" value="F:pyruvate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048039">
        <property type="term" value="F:ubiquinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042867">
        <property type="term" value="P:pyruvate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00850">
        <property type="entry name" value="POX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044261">
        <property type="entry name" value="PoxB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0446">Lipid-binding</keyword>
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    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="2">
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            <end position="413"/>
        </location>
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    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="2">
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    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="2">
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    <feature type="binding site" evidence="2">
        <location>
            <position position="51"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
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        <location>
            <begin position="277"/>
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        <ligand>
            <name>FAD</name>
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        <ligand>
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        <source>
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            <dbReference type="RuleBase" id="RU362132"/>
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            <dbReference type="Pfam" id="PF02776"/>
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        <source>
            <dbReference type="EMBL" id="BAF87353.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
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        <property type="protein sequence ID" value="BAF87395.1"/>
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    </dbReference>
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        <property type="gene ID" value="AZC_1397"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1397"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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            <begin position="4"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="270" mass="30188" checksum="2B6FE8B2B8A071E4" modified="2007-12-04" version="1">MRIATFNVNGVNGRLPPLLDWLRQSKPDVACLQELKAPHERFPAAELEQAGYGAVWLGQKAWNGVAILARGEMPVETRRGLPGDPDDIQSRYIEAAVGGVLIGCLYAPNGNPAPGAKFDYKLRWLERLRNYSAQMLDLDLPMVLAGDFNIMPEERDVYAPERWRDDALFRPEVRAAFADLRDDGWVDALRHLHPDARLYTFWKYLRNAFARDAGLRIDHLLLSPALAPRLVSAGVDRAVRGRDHASDHAPAWITLDAPTRGHAGGDRRTA</sequence>
</entry>
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        <name evidence="4" type="ordered locus">AZC_1402</name>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <authorList>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1420"/>
    <dbReference type="EnsemblBacteria" id="BAF87418">
        <property type="protein sequence ID" value="BAF87418"/>
        <property type="gene ID" value="AZC_1420"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1420"/>
    <dbReference type="eggNOG" id="COG2350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110355_3_1_5"/>
    <dbReference type="OMA" id="FREAGIW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="6"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="100" mass="10989" checksum="5565460565B4967D" modified="2007-12-04" version="1">MEPVLMLFAIHAVDRDGALSERLAHYDAHKAFLSDTSAFGVRIVMSGPLVSDDGQTMIGSLFLIEAEDRAAVERFHAADPFKKAGIWARVTITGFIRRQG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I267</accession>
    <name>RSMG_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="1">2.1.1.170</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="1">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmG</name>
        <name type="ordered locus">AZC_4710</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(527) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(527) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42732"/>
            <dbReference type="Rhea" id="RHEA-COMP:10209"/>
            <dbReference type="Rhea" id="RHEA-COMP:10210"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.170"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.170" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I267"/>
    <dbReference type="SMR" id="A8I267"/>
    <dbReference type="STRING" id="438753.AZC_4710"/>
    <dbReference type="EnsemblBacteria" id="BAF90708">
        <property type="protein sequence ID" value="BAF90708"/>
        <property type="gene ID" value="AZC_4710"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4710"/>
    <dbReference type="eggNOG" id="COG0357">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065341_1_0_5"/>
    <dbReference type="OMA" id="ICFPHLH"/>
    <dbReference type="OrthoDB" id="1590629at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000335310" description="Ribosomal RNA small subunit methyltransferase G">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="247"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="161"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="275" mass="29210" checksum="F4ED2CBDBD7A58BD" modified="2007-12-04" version="1">MGMASSHRLFGQLAPSSVMRACSATGRAVAKADRSSALDGGRSQVAALVSRETLARLDTIAEQLTRWQKTINLVAPNTLPDLWHRHIADSLQLVWLVPETVLNWADLGSGGGFPGLVVAAVLAEREGAHVTLVESDTRKAAFLREASRAAALPTRIVPERIEQASQRLAAGMQVVSARALAPLPKLLDLTEPFLQAGALGVFPKGRDWERELTDARKGWTLDLNLHRSVADPYGRILAITRAERAAPSAGSLSGGQPSTAGAASARPRTAKGKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2L7</accession>
    <name>A8I2L7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TRAP dicarboxylate transporter DctM subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dctM</name>
        <name evidence="10" type="ordered locus">AZC_1897</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
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                <person name="Miwa H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="414" mass="41804" checksum="BC8C71F20BFF6771" modified="2007-12-04" version="1">MTPSRLDATGHVLLRIARLLLGAGADSAHVHQRIETLAGQLGIEVQFFTGSERLLLMIASEGTYRTRVGHALGVMGIDAGRLVAVDEVVTALGAGRLDVEAADARLAEIEAHRSGYPDWIVVLAVAATAAALARLFGAAWPVVGAAFGAGLVNALVRLWLGRRGVLPAAVAALTACASGACAILPLRLTGDDPTLALVAAGMILVPGVPLINGIRDLVQGHAAIGLGRLANGIVVVLAIATGLSLASLIGGAAIPVSLQTANLPIGWDVLFATVCALGYALVFGAPLRAIPPILLCGALAHGLRTTVMALGGDIALGTLLGAFAAGLMASQVASRVAAPWTVFVFPAVVAMVPGSYAFRAMIGGLQLMRPGAENTVALLTATASALIGALVLTTAIAIGLLVASALHAVPLRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8I306</accession>
    <name>A8I306_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative hydantoin racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170492.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1965"/>
    <dbReference type="EnsemblBacteria" id="BAF87963">
        <property type="protein sequence ID" value="BAF87963"/>
        <property type="gene ID" value="AZC_1965"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1965"/>
    <dbReference type="eggNOG" id="COG4126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053002_0_0_5"/>
    <dbReference type="OrthoDB" id="1273626at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036361">
        <property type="term" value="F:racemase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="221" mass="22605" checksum="7ED542431948656A" modified="2007-12-04" version="1">MTAKGPILVINPNSDVAVTEALSRAVEPFRLGGGPAIECLTIAESPLGIMTQRDVYEAALRTADLAKARPDASAIVIACYSQPGLDLLRTETRRPVVGMQDAGVLAAMGLADRFGVIAVAEGSIPRHLANLARMGVMSRLAGEVAPARALTVAESGDPSASFDLLREAGTKLKQMGAGAIILGCAGMSPQRGILEEALGIPVVDATQAAVAQALGRVLVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I308</accession>
    <name>A8I308_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">D-hydantoinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1966</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="4">Carbamylation allows a single lysine to coordinate two divalent metal cations.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170493.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1966"/>
    <dbReference type="EnsemblBacteria" id="BAF87964">
        <property type="protein sequence ID" value="BAF87964"/>
        <property type="gene ID" value="AZC_1966"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1966"/>
    <dbReference type="eggNOG" id="COG0044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015572_2_0_5"/>
    <dbReference type="OMA" id="YEQWREK"/>
    <dbReference type="OrthoDB" id="906155at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01314">
        <property type="entry name" value="D-HYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011612">
        <property type="entry name" value="Urease_alpha_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00449">
        <property type="entry name" value="Urease_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02033">
        <property type="entry name" value="D-hydantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urease_alpha" evidence="6">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="53"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="4">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR611778-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="489" mass="53067" checksum="96ABFBBF70EB4400" modified="2007-12-04" version="1">MSDFAFDTVIHGGTIVTATDTYKADIGIRDGRIAAVAESLAGGTKRIDATGRLVMPGGIEGHAHIAQESSTKIMTADDYYTGSVSAAFGGNSSFIPFAAQHRGQSLDDVVAIYDERAAPNSVIDYSYHLIVSDPSPEVLEEQLPRAFARGITSFKVFMTYDLLNLGDGGMLDVLTVAKTHGALTMVHAENNDMVKWMNKRLAAKGLTAPKYHAISRPELAEEEAINRAVTLAKLVDAPLFVVHVSTEAGAAIIRRETQAGVKLFAETCPQYLALTREDLDRPGMEGAKFMCSPPVRDAQTQEALWRHIQAGTFMSVSSDHAPYRYDETGKLFNGADVPYPKIANGMPGIAMRLPWLFSEGVVKGRISANQFVALTSTNAAKVFGMARKGSIAPGFDADIAIWDPNETRVVSLDDQHDNMDYTPFEGLTVTGWPRTVLNRGELVVEERELVATRGRGRFVARDTVDLTGRPGYRAPELDPARNFGADIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8I321</accession>
    <name>A8I321_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1972</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1972"/>
    <dbReference type="EnsemblBacteria" id="BAF87970">
        <property type="protein sequence ID" value="BAF87970"/>
        <property type="gene ID" value="AZC_1972"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1972"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_5"/>
    <dbReference type="OMA" id="IMRLHRE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="31"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="383" mass="41044" checksum="3A189BD7F6C24261" modified="2007-12-04" version="1">MAYHLLRGDHARWMPDGMMQTGTQSEGGRALVVDGVTHRYGSSTAVENINLDIRSGELVALLGPSGCGKTTLLRIIAGFIRQTEGRIILGDEVVDDLGPNRRRIGIVFQNYALFPHLSIAENVAYGPAAQGVSKAEREAETKRLLDLVKLGHLADRLPRQLSGGQQQRVALARALAIKPRILLLDEPFAALDKNLRLDMQIEIKRLQRLSGITTVMVTHDQEEALSMADRVAVLSQGRLEQFASPTDIYDRPESLFVNTFVGSANQLAGQVLSAEAGGAIIRLDAGAELRARTPSSPLVAGQRCTVCLRPEHLEIADDPSGFAAVVEMGLPLGPTVVHEVRGADGAGIKVSEPRRAGTALLATGTPVRVRPLSADLATAYPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I332</accession>
    <name>A8I332_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative ABC transporter ATP-binding component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1977</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <begin position="1"/>
            <end position="120"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
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        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
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        <property type="entry name" value="Sedolisin_dom"/>
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            <begin position="242"/>
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        <location>
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    </evidence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase M50B family.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="MEROPS" id="M50.004"/>
    <dbReference type="EnsemblBacteria" id="BAF87698">
        <property type="protein sequence ID" value="BAF87698"/>
        <property type="gene ID" value="AZC_1700"/>
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    <dbReference type="KEGG" id="azc:AZC_1700"/>
    <dbReference type="eggNOG" id="COG0750">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR036034">
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        <property type="match status" value="1"/>
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        <property type="entry name" value="PDZ"/>
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    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
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        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="87"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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    <feature type="transmembrane region" description="Helical" evidence="9">
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="398"/>
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    <feature type="domain" description="PDZ" evidence="11">
        <location>
            <begin position="169"/>
            <end position="210"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
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            <dbReference type="ARBA" id="ARBA00022692"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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            <dbReference type="RuleBase" id="RU362031"/>
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    <evidence type="ECO:0000256" key="10">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
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            <dbReference type="EMBL" id="BAF87698.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
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            <dbReference type="Proteomes" id="UP000000270"/>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4I9</accession>
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        <recommendedName>
            <fullName evidence="8">Sec-independent protein translocase protein TatB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">tatB</name>
        <name evidence="10" type="ordered locus">AZC_1737</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
            <topology evidence="8">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TatB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170265.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1737"/>
    <dbReference type="EnsemblBacteria" id="BAF87735">
        <property type="protein sequence ID" value="BAF87735"/>
        <property type="gene ID" value="AZC_1737"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1737"/>
    <dbReference type="eggNOG" id="COG1826">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086034_1_3_5"/>
    <dbReference type="OMA" id="MFEVGWT"/>
    <dbReference type="OrthoDB" id="2073616at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00237">
        <property type="entry name" value="TatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018448">
        <property type="entry name" value="TatB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01410">
        <property type="entry name" value="tatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="170"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="205" mass="21234" checksum="ADAB04806C53F676" modified="2007-12-04" version="1">MFDIGWSEFMLIGVVALIVIGPKELPSVLRTVGKTVTKLRRMAGEFQGQFNEALREAELSDIRNDIGNIVGGVKDSVTKSFPGTEAFDPLRNIREDIRASVESATKPPEAAVAPEAPAVPAYDPHREMREAIAGAVAKATGSTAAAAATVTPLAAAPTVAVERAPAEPLVPLPGPAAEPVLDTGTDLSQNHGAPAQAEHKSATGA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4J4</accession>
    <name>SYS_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA synthetase</fullName>
            <shortName evidence="1">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">serS</name>
        <name type="ordered locus">AZC_1739</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170267.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I4J4"/>
    <dbReference type="SMR" id="A8I4J4"/>
    <dbReference type="STRING" id="438753.AZC_1739"/>
    <dbReference type="EnsemblBacteria" id="BAF87737">
        <property type="protein sequence ID" value="BAF87737"/>
        <property type="gene ID" value="AZC_1739"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1739"/>
    <dbReference type="eggNOG" id="COG0172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023797_1_1_5"/>
    <dbReference type="OMA" id="SPCFRRE"/>
    <dbReference type="OrthoDB" id="353391at2"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071631" description="Serine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="250"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="281"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="368"/>
            <end position="371"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <sequence length="445" mass="49325" checksum="BB7E435A966625BF" modified="2007-12-04" version="1">MHDIKWIREEPEALVRALVRRQVAKDEAVALRDKLLSLDTARRETLTKLEGLLARRNAASKEIGQAKAAKDEARAAALMDEVAKLKVDVPELEQSAKAIEGELDGLLAAIPNVPLESVPEGKDEHDNVELKVVGTKRNYAFTPKQHFELGEALGLMDFETASKLSGARFVVNKGPLARLERALGQFFLDMHVEQHGYTEVNPPLLVRDETMYGTAQLPKFFDDQFAVYAGSTQRAIGDETDAERYWLIPTAEVPLTNLVRDSILSEDELPLRFTANTPCFRAEAGSAGRDTRGMIRQHQFTKVEMVSITTPETSEEEHHRMLACAEAVLQKLDLHYRVVTLCTGDMGFASRKTFDIEVWLPGQNAYREISSCSVCGDFQARRMNARYRPAEGKGPRFVHTLNGSGVAVGRALVAVLETYQQEDGSIVVPDVLQSYMGGVTVIAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4L5</accession>
    <name>A8I4L5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">lpdA</name>
        <name evidence="16" type="ordered locus">AZC_1746</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
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            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
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        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
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    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
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    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
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    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
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        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
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    <feature type="binding site" evidence="11">
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            <end position="194"/>
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        <ligand>
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        <ligand>
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            <position position="278"/>
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        <ligand>
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    <feature type="binding site" evidence="11">
        <location>
            <position position="318"/>
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        <ligand>
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    <feature type="binding site" evidence="11">
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            <begin position="324"/>
            <end position="327"/>
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        <ligand>
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        </ligand>
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    <feature type="disulfide bond" description="Redox-active" evidence="12">
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            <begin position="43"/>
            <end position="48"/>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="17">
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
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                <person name="Suzuki S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    </reference>
    <reference evidence="2 3" key="5">
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                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    </evidence>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <text>acetyl-CoA + H2O + pyruvate = (3R)-citramalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19045"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30934"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from pyruvate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.182" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF87784">
        <property type="protein sequence ID" value="BAF87784"/>
        <property type="gene ID" value="AZC_1786"/>
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    <dbReference type="eggNOG" id="COG0119">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022158_7_0_5"/>
    <dbReference type="OMA" id="KSWDFHV"/>
    <dbReference type="OrthoDB" id="840579at2"/>
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        <property type="reaction ID" value="UER00066"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0043714">
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:2-isopropylmalate synthase activity"/>
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        <property type="term" value="P:isoleucine biosynthetic process"/>
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        <property type="term" value="P:leucine biosynthetic process"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
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        <property type="entry name" value="Aldolase_TIM"/>
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    <dbReference type="InterPro" id="IPR005675">
        <property type="entry name" value="Citramal_synthase"/>
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    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
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    <dbReference type="PANTHER" id="PTHR43538">
        <property type="entry name" value="PTHR43538"/>
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    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
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    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
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    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
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    <dbReference type="TIGRFAMs" id="TIGR00977">
        <property type="entry name" value="citramal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
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    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="12"/>
            <end position="277"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001418"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004743"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006154"/>
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    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012337"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022325"/>
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            <dbReference type="ARBA" id="ARBA00022624"/>
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    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
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    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87784.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="537" mass="57489" checksum="5A1FE6CF12FDAB07" modified="2007-12-04" version="1">MTAASPAARERLYLFDTTLRDGAQTNGVDFTLADKLNVIGLLNRLGVDYVEAGYPGANPTDTQLFAQKRPSAARVTAFGMTKRAGRSVSNDPGVAALLAAEADAICFVAKASAFQVRVALETTEEENLASIRESVAAAVAAGREALVDCEHFFDGFKENPDFALACAEAAYQAGARWVVLCDTNGGTLPHEVEAIVARVTARVPGSHVGIHAHNDTEQAVANSLAAVRAGARQIQGTLNGLGERCGNANLCSLIPTLLLKGDYAERFETGVSREALAEIGVVSRTLDEMLNRSPDRHAPYVGESAFATKAGIHASAILKDPATYEHVPPEAVGNQRRVLVSDQAGRSNVLAELERLGVPVDRADPRLARLLDEVKEREALGYAYEAADASFALLARRMLHSVPDFFTVERFSVKVERRYNAKGEMTTVAEAIVKVRVGDEVFISAAEGNGPVNALDVALRKDLGKYQPYIAGLRLTDYRVRILNGGTEAVTRVLVESTDESGARWTTVGVSPNIIDASFEALLDSITWQLLRSGAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8I564</accession>
    <name>A8I564_AZOC5</name>
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        <submittedName>
            <fullName evidence="10">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1824</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1824"/>
    <dbReference type="EnsemblBacteria" id="BAF87822">
        <property type="protein sequence ID" value="BAF87822"/>
        <property type="gene ID" value="AZC_1824"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1824"/>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002360_1_1_5"/>
    <dbReference type="OMA" id="RRFLTYH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="675"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="743"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="782"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="813"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="845"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="9">
        <location>
            <begin position="41"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="874" mass="91209" checksum="5FC7CA5AA44B60DF" modified="2007-12-04" version="1">MRCVGSRRPVRPRARVTVPRPDRSPMPLATRSPAASVPQPPPAATPPTGLSAEEARQRLVRHGPNALQQSRTRSFAAIIGGTLREPLFLLLLLAAGLYLLLGDIGEGLLLSAGALVSIGLVVLQEARSERALTALRALAEPVARVLRDGDHLRIPAREIVPGDLLLIGEGDRVPADGAVVAGDALTVDESALTGESVPVIKRVAPDGMAEALSRVPGGEDSCAIFAGTLNVRGQGVVQVVRTGADTRLGRIGASLATIETAATPLQQTMSRLIGKLGLLAIGFCGLVTLVYGLLRHDWIEGALAGITLSIALVPEEFPMVLAIFLALGAFRLARQKVLVRRSAVIETLGAATILCTDKTGTLTENRMALVAAQVAGRTVPVAPAGPPASAAGDLLRLARLASAPQPVDPMDRAVHAAVPAPESETLALLSTFPLQPDRLAFLQLWHLPDGLLFAAKGAPEAIARLCGLTPGEHADLDRDVSGLAAQGLRVLAVASRAAQDASEAPEDRPFAFGGLIAFADPVRPDVPGAIAEARRAGISVVMITGDYPTTALAIARQAGIESAAGVLTGPELAALPQDALPQRVQGVHVFARIMPEQKLAIIEALKAGGAVVAMTGDGVNDAPALEAAHIGIAMGQRGTDVAREAADLVLLDDRFVSILSGIRLGRRIFANLRKALTYVTAIHIPIAGLALLPVLLGLPPLLYPVHVVLLELVVDPLSALVFESEPSERHAMERPPRPASETLFGLRQIAFGCLQGGVLLAAVLGLYLWSSYAGHPEREARTLAFCALLLGNLVLAFAESAEADTAFFDLRRAAFWIIGTVAAGVLAAILLVPTLTDIFRLVRPTAGQCLLVLAVAALAGGWTGIVRRLGPAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5D6</accession>
    <name>A8I5D6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative membrane transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170792.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2265"/>
    <dbReference type="EnsemblBacteria" id="BAF88263">
        <property type="protein sequence ID" value="BAF88263"/>
        <property type="gene ID" value="AZC_2265"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2265"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021513_0_0_5"/>
    <dbReference type="OMA" id="CISYLDI"/>
    <dbReference type="OrthoDB" id="944044at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="596"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="618" mass="66199" checksum="A0709C587729773F" modified="2007-12-04" version="1">MFNDPGLARVTRPVHRESRTLVFLGALALIAVVYIGREVFVPVALAVLLSFVLSPVLLVLRRLRIPRTLGVAGVVMLTFIGLLALGAVVATQVGQLASDLPHYQANVRDKIRDLKSTASGSATMERVAGMLQDLSSELDRPDPQPKFQLDAAAAAQRPIPVEIRAPELGTLAMLRSLGEPLLHPLATTGIIFIFLIFILLQREDLRNRFIRLAGAHDIQRTTAALDDAGARLSRFLLTQVVLNAGFGCVIGLGLGLIGVPSAMLWGLLAAVLRFVPYIGAIIAALLPSALALAVDPGWSMVVWCIVLFAVVEPVVGHIIEPLLYGRSTGLSPVAVIASATFWTWLWGPIGLVLATPLTLCLVVLGRHVDQLEFLDVMLGDSPPLSAPELFYQRMLAGDPVEASGTAEDFLKDHALCAYVDEVALPALRLAQADFERGALDLERVERIRLSVQELVYTLGPGEDEAVAATESAPTADRPILCIGARTGLDEAAAMLAAMVLGANGLTAQVEGPSRLQRASLISLDATQAAMILVSAMDSNSTALLRYAVRRLRRRLPHAVILLGAWGLSDDRSLRNSLEEHGDPVSARMCDALSAARRLLPPPPPDKTLPRLERSAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5X8</accession>
    <name>A8I5X8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">iclR</name>
        <name evidence="5" type="ordered locus">AZC_2336</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="5 6" key="5">
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            <authorList>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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    <reference evidence="14 15" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 2 family.</text>
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            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAF88096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="388" mass="42223" checksum="352E2C0CA894BFEE" modified="2007-12-04" version="1">MSRFRLLAVMPLLAVLCGCNFVVLDPSGDIAVQQRDLILISTGLMLLIIIPVMVLTALFAWRYRQSNTAAKYDPEWHHSTKLELVIWSAPLAIIICLGAITWMATHLLDPYRPLSRIASDRPLPANVKPLEVQVVALDWKWLFIYPEFGIATVNEMAAPVDRPVTFSLTSSSVMNSFFVPALAGQIYTMPGMETKLHAVINAPGNFRGFSANYSGAGFTYMQFAFKGLSHDDFDKWVASVKAGKDGELSRAAYLELERPSEKVPVRYYPSVDPKLFNAIVNMCVEANKMCMADMMAIDAKGGQGLESARAVLPSYDKYARRGTVLGGEATYVVGVCSPEDLSAQAGSDRAPVAVGQRRVIGGPSAPVFTPISAPSAVPLPSLRTLSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7Y2</accession>
    <name>A8I7Y2_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">LrgB-like family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lrgB</name>
        <name evidence="6" type="ordered locus">AZC_2183</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2183"/>
    <dbReference type="EnsemblBacteria" id="BAF88181">
        <property type="protein sequence ID" value="BAF88181"/>
        <property type="gene ID" value="AZC_2183"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2183"/>
    <dbReference type="eggNOG" id="COG1346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_082099_2_0_5"/>
    <dbReference type="OMA" id="PLHTAYA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007300">
        <property type="entry name" value="CidB/LrgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30249">
        <property type="entry name" value="PTHR30249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04172">
        <property type="entry name" value="LrgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="229" mass="23926" checksum="8505BF92E98F2BF9" modified="2007-12-04" version="1">MQSLLGALFWSLVTIGCYALARLINQKARAWWSSPLMLTPVAVGAIVVLLHTGYASYIQGTHWLALMMGPATVAFAIPLYEHRATIRKHWPVLLAGVAIGSITAMGTAFALAYWLDIPSVLRASLMPRSTSTPFAMAASSEIGGMPELTAVFVIITGATGAAVGETLLRFMPVRSSLARGAVLGMGAHGAGVAKAHQMGSEEGSIAGLVMILAGCFNLLMAPIVAMVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8I883</accession>
    <name>A8I883_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murI</name>
        <name evidence="8" type="ordered locus">AZC_2222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170749.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2222"/>
    <dbReference type="EnsemblBacteria" id="BAF88220">
        <property type="protein sequence ID" value="BAF88220"/>
        <property type="gene ID" value="AZC_2222"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2222"/>
    <dbReference type="eggNOG" id="COG0796">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052344_2_0_5"/>
    <dbReference type="OMA" id="MPWGPRT"/>
    <dbReference type="OrthoDB" id="1718671at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Gevers D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <dbReference type="RuleBase" id="RU003860"/>
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            <dbReference type="EMBL" id="BAF88230.1"/>
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    </evidence>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="2">Carbamylation allows a single lysine to coordinate two divalent metal cations.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2674"/>
    <dbReference type="EnsemblBacteria" id="BAF88672">
        <property type="protein sequence ID" value="BAF88672"/>
        <property type="gene ID" value="AZC_2674"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2674"/>
    <dbReference type="eggNOG" id="COG0044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015572_2_0_5"/>
    <dbReference type="OMA" id="RNFVCSP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01314">
        <property type="entry name" value="D-HYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02033">
        <property type="entry name" value="D-hydantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="97"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611778-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="521" mass="56462" checksum="980A9A2C9A373FC5" modified="2007-12-04" version="1">MRGASETERPAVCGSLLWAVRRCAARDAFCARSVYGLVLLDRRHSAMALYDTIISGGTVVTASDRILCDVAIKDGKIVALGSGLTGADEVIDATGKLVLPGGVDAHVHIAQPSGEGIVMADDFESGTRSAALGGTTTVMPFCLQEKGQGLRAALKDYHAKADGECHVDVSFHLIISDPTEQVLGQELPALVEDGYTSFKIFMTYEGLALKDREILDVMSVARDTGALVMVHAENYDAIRFLTEQLEKRGQTAPRFHATSRPIAVEREATHRAISLAELVDVPVMIVHVSNREAMEQIRWAQNKGLTVLGETCTQYLVLTEKDLDGLGMEGAKYVCSPPPRDTESQEACWEGLRTGVFTIFSSDHCPFRYDDPQGKLTPKGRTSFRWVPNGIPGVGARLPVLFSEGVMKGRIDLERFVAVTATNPAKTYGLYPRKGTIAVGADADIAIWDPTKTQTLTHDLIRDGADYTPYEGIEITGWPVHTLLRGKTVARDGEVVGQKGLGQHLSRAKSPFAVQRDPVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I931</accession>
    <name>A8I931_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2737</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171261.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2737"/>
    <dbReference type="EnsemblBacteria" id="BAF88735">
        <property type="protein sequence ID" value="BAF88735"/>
        <property type="gene ID" value="AZC_2737"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2737"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_1_5"/>
    <dbReference type="OMA" id="FWNVRPA"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724252" evidence="4">
        <location>
            <begin position="27"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="72"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="527" mass="57968" checksum="69FA148145DACE0B" modified="2007-12-04" version="1">MLLSRRSFLRAAAAAPLVSLPSIVRAQSQTTLRFVPVIDLTFTDPIYSTAQVSRNHGFMVYDTLYGMNSALEVSPQMVEGHLVSNDGLQWDLTLREGLVWHDGEKVLSRDCVASIKRWAKRDGFGAELMAATDEISAPDDRTIRFRLKRPFPLLPSALGKAAVQAPFMMPERHATQDPFKPLTEVVGSGPFRFVADERVQGARNVYARFERYKPRESGTPDWTAGPKIVHYDRVVWTTMPDAATGAAALQTGEQDWQETAPHDLLPILKKAKGVSTRILDPRGYACMLRVNHLQPPFDNPAIRRALFGAIDQSAFMTAVAGDDPQYQTTPIGFFAPGTPFASDVGLDVFNGPRDYAKVKAALKAAGYNGEKVVLMVPANSAAQKPLGDVAFDMLQQVGMNVEYAAMEFGAILQRQLKKDPVDQGGWSAGVGNWQGIDWLNPAGNTNLRGDAGTAGWYKSEKMGALRAQWLSAPTLAEQQRICRDIQTLAFEEVPYYPVGLYKQPTAYRSAITGIMNGTAVFWNVRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8I945</accession>
    <name>A8I945_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2742</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <dbReference type="KEGG" id="azc:AZC_2742"/>
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        <property type="entry name" value="DPRP"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF48173"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <sequence length="526" mass="59076" checksum="D7E966432C324E8A" modified="2007-12-04" version="1">MTLRGDMAKSGTLRFVLGDQLSPGLSALRGGDRKRDVVLMVEVAEETTYVPHHRKKIAFILAAMRAFARELEADGWRVDYVRLADPVNTGSFSGELERAVGRWDPERVAATEAGEWRVLEAQKAWADAPWMEGRTLDLSPDDRFLCPEAFFRAWAGERKGLRMEFFYREMRRRTGLLMDGGEPCGGRWNFDAENRKPARADLFMPRPPRFAPSADTREVLELVAARFADHFGDIKPFWFAVTRADAETAFAHFLTEALPRFGDYQDAMLEGEPFLYHAVIALYLNVGLLSPLEVCQRAEAEYRAGRAPLNAVEGFIRQILGWREYVRGIYWLTMPGYLDRNALAASRPLPSLYWSGETRMACMAAAIGQTKAEAYAHHIQRLMVTGNFALLAGIAPRQVHEWYLAVYADAFEWVEAPNTIGMSQFADGGLLGSKPYAASGAYIDRMSDYCGGCAYDVAAKTGPKACPFNYLYWDFLARNRTVLAGNARLATAYRTFDRLDEKRRDAIAESAHAFLTRLDATGSDLD</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA07</accession>
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        <name evidence="7" type="ordered locus">AZC_2448</name>
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    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <property type="protein sequence ID" value="BAF88446"/>
        <property type="gene ID" value="AZC_2448"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
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    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ABC_TM1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
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        <location>
            <begin position="27"/>
            <end position="50"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="161"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88446.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="270" mass="29013" checksum="45926243476631AE" modified="2007-12-04" version="1">MSTSSLAQPAQPPSGASLRLLLPLLRALRGLAILVAVFAAWEALVVAFAIRPYYLPRPTVIFAALWQTPAPYVQGFLRTLSETLLGFVAGGVFGIGIGLLFFRARALRELVFPLFIVSQTIPVIAFGALVVLWFGNTLLAKAAIAFYLTFFPVTVNTLLGLESVDPRQEALLRSFGASPLQLLTRLQFPTALPQIFVALRLASSLALVGAIVGEWFGDTVGLGVLLLQGMYTENVVSIWATLLVSALLGTGFYALVAAAERAFVFWGAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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    </evidence>
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    </evidence>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    <sequence length="86" mass="9593" checksum="2223833600F9FE42" modified="2007-12-04" version="1">MPPEGEFLLQNLRATGIVAVPDLHKHRPSPLQHRAVEWGLSSLEEGETLRIEHGPSIRPPEGRHWGSARGPFRCRAQAQGPSQLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC62</accession>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Mediates magnesium influx to the cytosol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + Mg(2+)(out) = ADP + H(+) + Mg(2+)(in) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10260"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.14"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.</text>
    </comment>
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    <dbReference type="STRING" id="438753.AZC_2983"/>
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        <property type="protein sequence ID" value="BAF88981"/>
        <property type="gene ID" value="AZC_2983"/>
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    <dbReference type="KEGG" id="azc:AZC_2983"/>
    <dbReference type="eggNOG" id="COG0474">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_002360_6_3_5"/>
    <dbReference type="OMA" id="GRVEVIC"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:P-type magnesium transporter activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="77"/>
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    <feature type="transmembrane region" description="Helical" evidence="14">
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    <feature type="transmembrane region" description="Helical" evidence="14">
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            <begin position="822"/>
            <end position="843"/>
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    <feature type="domain" description="Cation_ATPase_N" evidence="15">
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            <end position="97"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
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    </evidence>
    <sequence length="867" mass="90376" checksum="48992F7AA755AD49" modified="2007-12-04" version="1">MTALPSTAHLRAGAAPTGAHSEAPFWVRGAAAQLEMLASRPEGLTAAEAAERLASHGPNVAVAAGRKSLLAKLLKRLTEPLVAILLIAAGVSGATGDWQSFVIILLIVLFSIGLDLFQEEKAEAAVEALKRSVAVSARVRRGGQAIAIPVREVVPGDVVELTAGDLVPADGILLSSRGALANEVALTGEAYGAEKAAGDCAALDIAEATNALFAGTSIVGGVAVMLVTATGADTRFGHVAASVQAKVAPGAFERGIHGLGMLILRLTGFLVLFVLLTQLLKQGLTLEAFLFAVALAVGLTPELLPMVTTVTLSRGAVRMAARQVVVKRLAAIHDLGAMDVLCTDKTGTLTQARIALVGSFDAEGLESPRAVEAGRLNSRFVSGLHSNLDDALLADAPADAGSLRCLADRPFDFDTRRATVLLSEGLSRRLVTKGAAEMVLPLCHAYARQDGTLAPLDADARARLSERMEAKGREGFRLLAVASAPADDALADVEEAGAPYVFLGCLVFLDPPKDSATEAIARLSAAGVRVKIVSGDAGAVVRHLVETLHLPASGLLTGAEMEDMSDLALAAAVEKTDLFVRVSPEQKSRIVRALRARGHTVGFMGDGINDAPAIHAADVGLSVDGGTDVAREAADIILLAPDLGVLADGVREGRRTYANIMKYVRMGTSSNFGNMLSMAAASLVLPFLPLAPLQILLNNLLYDLSEIGIPFDQADEADLMRPQAWDMGAVLRFTLIMGPLSSVFDLVTFAVLSLGFSAPPDEFRTAWFVESIATQILVIFLIRTRGPAWASRPDRVLAATSLGALAVALLIALTPVGSVVGFVPLPASLLGAIAMLTALYLACAEGLKRFAIKPSAQGPRSAGRRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEM8</accession>
    <name>A8IEM8_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3512</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172035.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3512"/>
    <dbReference type="EnsemblBacteria" id="BAF89510">
        <property type="protein sequence ID" value="BAF89510"/>
        <property type="gene ID" value="AZC_3512"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3512"/>
    <dbReference type="eggNOG" id="COG5426">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_400015_0_0_5"/>
    <dbReference type="OMA" id="WLMKEPE"/>
    <dbReference type="OrthoDB" id="102505at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="660"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="688" mass="74131" checksum="63A360CDE9678967" modified="2007-12-04" version="1">MSYGLAFEPFLPWPMLGALAVVALVLAVLLVGARTRGGAIRALALLVGLIALANPSLTREEREPLSSVVAVVVDKSASQNFGDRTAQTQAARAALDERLKRIPGLEIRTIEADARDGETDGTRLFSALSAGLADVPPERVAGAIMITDGRVHDVPEQASALGFNAPIHGLITGQAGERDRRVALEKAPRFGIVGQRQMLTFRVTDEGVPAGARVGVIVRRDGEVIANPVVTAGRPAQVEVEIAHAGANIIEVEAPPLEGELTLVNNRAAVSIDGVRDKLRVLLVSGEPNVGERTWRNLLKSDANVDLVHFTILRPPEKQDGTPINELSLIAFPTRELFQTKIRDFDLIIFDRYAQQGVLPQVYFDNIVRYVRNGGALLVAAGTDFVDTGSLYNTPLEDILPAAPTGQTTEAPYVAKLTDLGKRHPVTRGLPGSESDPPHWSRFFRVVDAEARSGVTVLSAPGDKPVLQLDRVGQGRVALLLSDHFWLWARGYDGGGPYIDLLRRLSHWLMKEPDLEEERLKLSTSGRDLVVERQTMGESVPVAQVTTPSGAVRNLTLTQAEPGLWRATTPADELGLWRAVNGQLTALTNIGPLNPKEFAEVTSTKDWLAPIATATGGGLWRLSELKGSVPRVVAVSSGERLAGDDWMGLRTRDVSVVRGIGLFPVFAGLSGLLLLLGVITAAWVREGR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IES7</accession>
    <name>ILVD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="1">DAD</shortName>
            <ecNumber evidence="1">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ilvD</name>
        <name type="ordered locus">AZC_3530</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27695"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="1">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IlvD/Edd family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172053.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IES7"/>
    <dbReference type="SMR" id="A8IES7"/>
    <dbReference type="STRING" id="438753.AZC_3530"/>
    <dbReference type="EnsemblBacteria" id="BAF89528">
        <property type="protein sequence ID" value="BAF89528"/>
        <property type="gene ID" value="AZC_3530"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3530"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014271_4_2_5"/>
    <dbReference type="OMA" id="TQGRNMA"/>
    <dbReference type="OrthoDB" id="193579at2"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000070949" description="Dihydroxy-acid dehydratase">
        <location>
            <begin position="1"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="518"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="492"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="1">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <sequence length="617" mass="65732" checksum="3651B0272B565D2E" modified="2007-12-04" version="1">MPAYRSRTSTHGRNMAGARGLWRATGMKDGDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEKAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGKVLLSTGEKKVDLIDAMIAAADDRVSDEDVKVMERSACPTCGSCSGMFTANSMNCLTEALGLALPGNGSVLATHADRERLFVEAGHLVVDLARRYYEQDDAGVLPRTIASFKAFENAMTLDISMGGSTNTVLHLLAAANEGEVPFTMADIDRLSRKVPVLCKVAPAVANIHMEDVHRAGGIMGILGELDRAGLIHTDLPTVHAPSMKDALERWDVTRTKAESVTTFYRAAPGGVPTQVAFSQSRRWDDLDTDRASGVIRDFEHAYSKDGGLAVLFGNIAEDGCIVKTAGVDASILKFTGPARIFESQDAAVEAILANGKIKAGDIVLIRYEGPRGGPGMQEMLYPTSYLKSKGLGKACALVTDGRFSGGSSGLSIGHVSPEAAEGGAIGLVEEGDTIEIDIPNRRIHLAISDEEMARRRAAMEAKGDAAWKPKDRQRVVSQALQAYAALTTSAARGAVRDVKSLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF00</accession>
    <name>A8IF00_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3557</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Liu CT."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <sequence length="540" mass="57343" checksum="20AD937036CBE0BB" modified="2007-12-04" version="1">MTIQIPYAAALAAIASGSAPPVRSDDLPVETLLARFHPDHGPRARVPLRIGANAGDACHPELARLLESNALIDDLDLARATPLATDVLVIGGGGAGAAAAVTAARQGARVIIAGKLRIGDSNTVMAEGGIQAAVGAEDSLQRHFDDTVRGGHGRGEHMLIAQMVRDAPDVIRWLIDLGMAFDLSQDKALGQTLVRKRAGGTTAARILCHRDFTGLEMMRVLREAVELQGGIEQFMRCPAVELLSHEDGSCAGAVLYDLERRSFLLVRANAVVLATGGSGRLHLQGFPTSNHYGATADGLVLAYRLGARMRDLDSFQYHPTGVAWPRHLAGGLISEAARSAGAVLLNGLGERFVDELQPRDVVAAAILRECAEQRGIMRDGETGVFLDVRGALAARPDLLERDLVSLGHLAAKCGLDPRTEPFLIYPTLHYQNGGIEIDGDGATAVPGLFCAGEVTGGIHGRNRLMGNALLDIISFGRRAGARAAEARPPHAPGRGGLSHVHRWRRELARAGLPADLRAPQLYPTYGNFALRRGTTDRGNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH86</accession>
    <name>A8IH86_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168719.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0188"/>
    <dbReference type="ESTHER" id="azoc5-a8ih86">
        <property type="family name" value="Duf_3141"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86186">
        <property type="protein sequence ID" value="BAF86186"/>
        <property type="gene ID" value="AZC_0188"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0188"/>
    <dbReference type="eggNOG" id="COG3243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014618_0_0_5"/>
    <dbReference type="OMA" id="GHPCYFI"/>
    <dbReference type="OrthoDB" id="400860at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024501">
        <property type="entry name" value="DUF3141"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11339">
        <property type="entry name" value="DUF3141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="779" mass="84749" checksum="242C04DE639485EE" modified="2007-12-04" version="1">MAGESATPAPLQPGTWGQPGHQAAPWSGVFAEAWSRAFTGTAPLPPGIGTLPAGPLVDYLVDAAQRSVLFIDLMRRRGNEQQDITSRPMATVLSFDHDVLVSGRALPRPINYFLSRIVPPPGAKVDPDKRPVVVVDPRAGQGPGIGGFKTQSEIGEALANGHPVYFIGFSAQPEPGQTFLDVVEGQVSFFERIVAMHPDAPRPFAIGNCQAGYQTLMVAMLRPDLFGPCMVAGSPMSYWQGVHGKNPMRYSGGLLGGSWLTALVSDLGRGKFDGTWLILNFDSLNPANWLWGKQYDLYAAVDTEAQRYLGFEKWWGDFITLNGDEIQFLVDELFIGDGLTRNEMRSSDGTVFDLRNIASPLIVFTSLGDNISPPPQTLGWILDLYKDVDAIHAEGRTIVYCLNQTVGHLAIFVSAKVGAKEDEEMVRLMDLIDCLPPGLYELVISPASEEEVKAGGHPWHSRFEARSLEDIRAFGRNSVEDDRAFAAVRRVSEINLSLYRTFLQPAVRALANPHMAELLFATNPLRLSYSLFADSNPFMKPVAKAAAEVTAARKPVPPDNPFLAVQKLWSDQISAGLDAFRDLRDRAVEQAFFGIYGSPVLQGMLGLNLDEKVRELPPTSPQKRAFLTQKMAEFRDRVDEGGFNEALVRSVLFVIAADRQLDERCAAALKETCLRLTQLSISDFKSLVRRQFYILLLEGIAAVEAIATLVPDGAARQSLLNDAAAVAGANGTLTIGEQQNIEKLAEVLGVAAPHSPAPVLPADTHRSAPSTLQIAPAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8II75</accession>
    <name>A8II75_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative multidrug efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3371</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171894.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3371"/>
    <dbReference type="EnsemblBacteria" id="BAF89369">
        <property type="protein sequence ID" value="BAF89369"/>
        <property type="gene ID" value="AZC_3371"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3371"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000960_28_0_5"/>
    <dbReference type="OMA" id="TALFMEN"/>
    <dbReference type="OrthoDB" id="1558246at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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            <dbReference type="PROSITE" id="PS50850"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF89369.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="483" mass="51008" checksum="C0C8B953B3CF1BD7" modified="2007-12-04" version="1">MLASALPRHILVPLIVACALFMEQVDSTVISTSLPAIAASLHDDPVALKLALTSYLLSLAVFIPASGWCADRFGARTVFRSAIVIFTLGSILCGLSTSLLDFVIYRIIQGMGGAMMVPVGRLVILRSVPKSEIVSALAWLTIPALLGPVMGPPLGGFITTYFDWRLIFFINVPIGILGIILATRFIENVREEDVPPLDLHGLVLSGIGLSGLVFGLAVLGQHLVPYWAAAGVTAIGIVALGFYVRHARRTPHAVLDLSLLRIPTFRAGVVGGSLFRIGVGALPFALPLMLQLTFGLSPFASGMLTFASSAGALVMKTTARPILRRFGFWRVLVVNALISSAFIGANALFTPETPHAAIVAVLLMGGFFRSLEFTAINALSYADVSQPEMSRATSFVSVAQQVSLSLGVALVGMVLEAMRSARGETALQLADFTPAFLIVAGVSALAVFSFMNLPKDAGAELSGHKEKPSTLPDPRGEVNTAGS</sequence>
</entry>
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    <accession>A8II99</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171902.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3379"/>
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    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_011142_1_0_5"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042187">
        <property type="entry name" value="Flagellin_C_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="4">
        <location>
            <begin position="4"/>
            <end position="135"/>
        </location>
    </feature>
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        <location>
            <begin position="266"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="352" mass="35748" checksum="1C0816033B9818CF" modified="2007-12-04" version="1">MTSIITNNAASVALATLRSINDSLNTTNDRVSTGKKINSAADGAAYWNISTTLTSDNGALGAVKDAINLDMSSVKTTNTGLTQIMNSLNTIKQALVSAQSSTADRTSLQKNIANAVSDISSAASSAVVNGANWLSVDSSATGFNANKSLLANFSRASGVVTVGTTTLDTGAFAVYDAKTNSTSTGTSSTIDTAVTAVATSASVSGGLTVAVGTNAGNLKGFMDTTYSISGSVGGTTVAAFTASIANIDISSLTSSDVDLAKLSSYMKIVSATIDGLQAGSTALGTTQTRLTSQQNFAQSLIDINTSSIGSLVDANMEEESTKLKALQTQQQLAVQSLSIANNSTSNIMTLFR</sequence>
</entry>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the biosynthesis of the iron-molybdenum cofactor (FeMo-co or M-cluster) found in the dinitrogenase enzyme of the nitrogenase complex in nitrogen-fixing microorganisms. NifB catalyzes the crucial step of radical SAM-dependent carbide insertion that occurs concomitant with the insertion of a 9th sulfur and the rearrangement/coupling of two [4Fe-4S] clusters into a [8Fe-9S-C] cluster, the precursor to the M-cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the radical SAM superfamily. NifB family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF89412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171937.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="SMR" id="A8IIJ5"/>
    <dbReference type="STRING" id="438753.AZC_3414"/>
    <dbReference type="EnsemblBacteria" id="BAF89412">
        <property type="protein sequence ID" value="BAF89412"/>
        <property type="gene ID" value="AZC_3414"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3414"/>
    <dbReference type="eggNOG" id="COG0535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027639_0_0_5"/>
    <dbReference type="OMA" id="NHPCYSE"/>
    <dbReference type="OrthoDB" id="1199289at2"/>
    <dbReference type="UniPathway" id="UPA00782"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00852">
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    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003731">
        <property type="entry name" value="Di-Nase_FeMo-co_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036105">
        <property type="entry name" value="DiNase_FeMo-co_biosyn_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005980">
        <property type="entry name" value="Nase_CF_NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034165">
        <property type="entry name" value="NifB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43787:SF3">
        <property type="entry name" value="PTHR43787:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02579">
        <property type="entry name" value="Nitro_FeMo-Co"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53146">
        <property type="entry name" value="SSF53146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01290">
        <property type="entry name" value="nifB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="69"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAF89412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="519" mass="56032" checksum="28181BD1280C019E" modified="2007-12-04" version="1">MHGLTQDVSSAGSAPDMGEIMQAIAEHKGCGTSGGSGKASCGSGAGQGDLPTEIWEKVKNHPCYSEEAHHHYARMHVAVAPACNIQCNYCNRKYDCANESRPGVVSEKLSPEQAAKKVLAVASTIPQMTVLGIAGPGDPLANPEKTFKTFELISKTAPDIKLCLSTNGLTLPDHVDTIASYNVDHVTITINMVDPEIGAKIYPWVFYKHKRYTGIDAAKILTDRQLLGLEMLTARGILTKINSVMIPGINDQHLVEVNKAVKSRGAFLHNIMPLISAPEHGTVFGLNGQRGPTAQELKALQDSCEGEMNMMRHCRQCRADAVGLLGEDRSAEFTTDKIMAMEVNYDMEGRKAYQAAVEEERVAKVAAKQEELAGLAGEMSDIKLLVAVATKGSGLINEHFGHAKEFQVYELSTAGAKFVGHRRVDLYCQGGYGEEDSLETIIRAINDCHAVFVAKIGGCPKSDLLKAGIEPVDQFAHEFIEKSAIGWFKDYLAKVNSGEIEHVARGDAAIRQGALISAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ18</accession>
    <name>A8IJ18_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative molybdenum cofactor biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0235"/>
    <dbReference type="EnsemblBacteria" id="BAF86233">
        <property type="protein sequence ID" value="BAF86233"/>
        <property type="gene ID" value="AZC_0235"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0235"/>
    <dbReference type="eggNOG" id="COG0476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013325_10_0_5"/>
    <dbReference type="OMA" id="MIYDALE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="11"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="270" mass="28070" checksum="C5C5DE0979A66E58" modified="2007-12-04" version="1">MAFSADEIERYARHIVLHDVGGPGQQKLKAAKVLVVGAGGLGAPALLYLAAAGVGRLIIVDDDAVSLSNLQRQVIHRTADIGRPKTDSAKEAVEALNPHVEVETHAVRLTPANALDLISRADVVLDGSDNFATRYLVSDACVLAKKTLVTAALGTFDATLTTISAHETGPDGTPNPTYRCLFPEPPPPGTVAPCAEAGVLGALAGIAGSMAALEAIRAIVGFGEGLVGKLLMMDARSMRFETLSYGWDEDNPLTGTGARITDLSAHEKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ91</accession>
    <name>A8IJ91_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0268</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <property type="gene ID" value="AZC_0344"/>
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    <evidence type="ECO:0000259" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="154" mass="16520" checksum="3D4351E0DB7CC59B" modified="2007-12-04" version="1">MPLADLVAREAVFPSLRASSKKQALQELAQHAATLLGRDAREIFETLLQRERLGSTGVGNGIAIPHGKLPKLDKLFGAFARLEKPIDFEALDGEPVDLVFLLLAPEAAGADHLKSLARIARMLRDPATADKLRGTREAADIYALLTTTPASDAA</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
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        <source>
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    </evidence>
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    </evidence>
    <sequence length="274" mass="30432" checksum="405DD9A670186B23" modified="2007-12-04" version="1">MNEDAPTFVQLEDVRLTYGRGERMVEALGTTNLKIGQGDFVALVGPSGCGKSTILKLVTGLIPASVGYVFVAGREVGAEPVRVGMAFQNPTLLPWLTIRQNVMLPLKIVPPFRQQYRAKKKTEFRDRAEALLAQVGLSGFGDKFPWQLSGGMLQRASLCRALIHDPQLLMLDEPFGALDQFTREELWAILQDLWLTRRPTVLLVTHDLKEAGYLANRVCVMRARPGRIVEDCHVDFARPRTIEMTYEPGFVSLTQRLRGLIVSARSPAAVEASA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3900"/>
    <dbReference type="EnsemblBacteria" id="BAF89898">
        <property type="protein sequence ID" value="BAF89898"/>
        <property type="gene ID" value="AZC_3900"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3900"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_0_0_5"/>
    <dbReference type="OMA" id="DCCATTT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="2">
        <location>
            <begin position="73"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="282" mass="29646" checksum="018DE9446722A5DB" modified="2007-12-04" version="1">MEYSAIDSITPPCVVSRGSGAPPPASREPRPMTSAGSVTAGLSTLSFARPVPAPRPVAVPATPQDAEIDLARTALVIVDMQNDFLHPDGWFPRLGVDAAPLLAIVPRLKALAAAARAAGLPVIFVNWGVRADRAELSAPLLAKAGASGRRPVYGDPSASGRGRILVEGDWGAATIDALAPERGDLVVHKHRLSGFHDNEFDSILRNRGIDTLLFSGVNIDRCVFSTLCDASFRGYGCLLVEDACATVSPAYVSDAILFLVRQLYGVTLASDALIAALEAQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKK0</accession>
    <name>A8IKK0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE</fullName>
            <ecNumber evidence="6">2.1.1.163</ecNumber>
            <ecNumber evidence="6">2.1.1.201</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">2-methoxy-6-polyprenyl-1,4-benzoquinol methylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Demethylmenaquinone methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">ubiE</name>
        <name evidence="7" type="ordered locus">AZC_3919</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-methoxy-6-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-methionine = a 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:28286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="EC" id="2.1.1.201"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="6"/>
    <dbReference type="EC" id="2.1.1.201" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172439.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3919"/>
    <dbReference type="EnsemblBacteria" id="BAF89917">
        <property type="protein sequence ID" value="BAF89917"/>
        <property type="gene ID" value="AZC_3919"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3919"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037990_0_0_5"/>
    <dbReference type="OMA" id="VRNFENL"/>
    <dbReference type="OrthoDB" id="1431378at2"/>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043333">
        <property type="term" value="F:2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172525.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4005"/>
    <dbReference type="EnsemblBacteria" id="BAF90003">
        <property type="protein sequence ID" value="BAF90003"/>
        <property type="gene ID" value="AZC_4005"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4005"/>
    <dbReference type="eggNOG" id="ENOG5033B4W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_173404_0_0_5"/>
    <dbReference type="OMA" id="DYHFACN"/>
    <dbReference type="OrthoDB" id="2004503at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="93" mass="10261" checksum="8CE4CDEA4256B165" modified="2007-12-04" version="1">MACDRCDALCLDWPIRTPGELEHALTVARDNLADGTLTEQPDHPDNSVLRMGQDRGWPDIVSVDFTCTTCGARFHLACETYHGGGGGWSFRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILE0</accession>
    <name>A8ILE0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">O-succinylhomoserine sulfhydrylase</fullName>
            <shortName evidence="2">OSH sulfhydrylase</shortName>
            <shortName evidence="2">OSHS sulfhydrylase</shortName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">metZ</name>
        <name evidence="6" type="ordered locus">AZC_4021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>hydrogen sulfide + O-succinyl-L-homoserine = L-homocysteine + succinate</text>
            <dbReference type="Rhea" id="RHEA:27826"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57661"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from O-succinyl-L-homoserine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the trans-sulfuration enzymes family. MetZ subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172541.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4021"/>
    <dbReference type="EnsemblBacteria" id="BAF90019">
        <property type="protein sequence ID" value="BAF90019"/>
        <property type="gene ID" value="AZC_4021"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4021"/>
    <dbReference type="eggNOG" id="COG0626">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018986_2_0_5"/>
    <dbReference type="OMA" id="THGGIIV"/>
    <dbReference type="OrthoDB" id="637281at2"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071268">
        <property type="term" value="P:homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02056">
        <property type="entry name" value="MetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006234">
        <property type="entry name" value="O-succ-hSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01325">
        <property type="entry name" value="O_suc_HS_sulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="2 3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="400" mass="42877" checksum="9A5E2788428B6F91" modified="2007-12-04" version="1">MASKFVPPDPSTLHPETLLVHGGTTRSPYGETSEALYLTQGFVYDNAEACEARFKGEDPGFVYSRYGNPTTAMFEERMALLDGAEAARATASGMAAVNASLLCQLKAGDHVVAARALFGSCRWILEDFLPRYGVETTLVNGTDLDAWKAAARPNTKIFFLESPTNPTLEIIDVKAVADIAHAQGALLIVDNVFATPLLQKPFELGADVVVYSATKHIDGQGRCLGGVVLSSQQFVTDHLQTFLRQTGPSISPFNAWVLLKGLETLGLRVERAQSSAATLADALAAEPKVEKVLYPFRADHPQAALARRQMTGGGTLVTFVVGGGKEGAFRFANALKVIRISNNLGDSKSLLTHPATTTHQRFTPEARAEMGISDGLVRLSVGLEHPDDLVSDIVQALKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILX4</accession>
    <name>A8ILX4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fis-type protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0438</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="KEGG" id="azc:AZC_0438"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="112"/>
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    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="47"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="231" mass="23897" checksum="89552290E2FEC46C" modified="2007-12-04" version="1">MVEDDFFECSRVESALLHQGHEVVCVGDGDAALARLDAEPFDLMLLDLVLPGLDGMGVLRTLEARGSSVPVIVSVTPAGIDGAASAIRAGARDFVVKPAGALRLKVAITNALALAGAGAVSERPAAPVAGAPVRLRLAHDADWTAQDRSGQPAPKACGINESLPFLDALGHTRTLEQLEADAIRAAVSLYGGRMSEVARRLGIGRSTLYRKLSALGLPVPEPVSPLAVAAE</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <property type="protein sequence ID" value="BAF86463"/>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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        <property type="entry name" value="HTH_IclR"/>
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    </dbReference>
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        <property type="entry name" value="IclR"/>
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        <location>
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    <evidence type="ECO:0000256" key="1">
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        <source>
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    <evidence type="ECO:0000259" key="4">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="32"/>
            <end position="383"/>
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    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="394" mass="42738" checksum="3A0BDC0E1F2A8680" modified="2007-12-04" version="1">MLTTVAAFDRIGEENAFAVLARATTLAAQGRDIINLGIGQPDFRTPEHIVEAAVKALKDGQHGYTPSVGIQPLREAVARDLHKRFDVEVDPGLVMIMPGGKVTMYAAILLFGEPGAEILYPDPGFPIYRSMIEYTGATPIPVPIREENGFAFSAEETLALITPKTRLLIINSPANPTGGVTPKAEIDKLVKGLADHPHVALMSDEIYDQFLFDGERHQTLLAYPEIRDRLILLNGWSKTYAMTGWRLGYSIWPQALYDKVRKLSVNAWSCVNAATQYAGIAALEGPQEPVAAMLAEFDKRRRLVVEGLNALPGVTCAKPKGAFYAFPNVSRTGWTSAKALASALLEDAGVATIGGPDFGVHGEGYIRLSYANSAENIARALERMGAFLSERKVA</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <name>[4Fe-4S] cluster</name>
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        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer of a large and a small subunit.</text>
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    <comment type="similarity">
        <text evidence="2">Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <keyword evidence="5 11" id="KW-0004">4Fe-4S</keyword>
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    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
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    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
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    <feature type="domain" description="NiFe_hyd_SSU_C" evidence="13">
        <location>
            <begin position="207"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
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            <label>1</label>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0638"/>
    <dbReference type="EnsemblBacteria" id="BAF86636">
        <property type="protein sequence ID" value="BAF86636"/>
        <property type="gene ID" value="AZC_0638"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0638"/>
    <dbReference type="eggNOG" id="ENOG503024W">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129708_0_0_5"/>
    <dbReference type="OMA" id="EINHIAF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="143" mass="16123" checksum="63F6CF5757D3A273" modified="2007-12-04" version="1">MVNRATVGEQRLMVYERALAECLRHFLGELFYTNAGVIIGYIHGRQDQNIDDIVASSAELSLRPGLLHYTHHANIVEEWGAPPVVTLEMELQHIDLTAYFRIEFDGKGIGITIEGIVFTEPVASIEDSFLRFQHALDECRLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPQ5</accession>
    <name>A8IPQ5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_0672</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169203.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0672"/>
    <dbReference type="EnsemblBacteria" id="BAF86670">
        <property type="protein sequence ID" value="BAF86670"/>
        <property type="gene ID" value="AZC_0672"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0672"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_1_5"/>
    <dbReference type="OMA" id="IEGPCHH"/>
    <dbReference type="OrthoDB" id="750230at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="294" mass="31155" checksum="89CCF18872415D93" modified="2007-12-04" version="1">MTLDQLKVFVAVADHLHMTRAAEALHMTQSAVSASIAALEQSCGQPLFDRVGRRIELTAAGRLFVGEAQAILKRVAQARDALSDLAGLARGTLTLHASQTIANYWLAPRMNAFHAAHPGIRLELGIGNTTQVAAAVRDGLADLGFVEGEVEEPLIVRRRVPGDELVLVASADAPYADLDTLSAHDIAAMPFVLREPGSGTRQMFEAACRRLGVKPQAVTIVFELPSNEAVLSAVAAGAGATVISRLVAEAGLKAGTLKALPLALPPRNFYVLHHGERDRSRAAEAFVGFIAPPK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-02-01" modified="2022-08-03" version="112" xmlns="http://uniprot.org/uniprot">
    <accession>P33984</accession>
    <accession>A8IKL6</accession>
    <name>RP54_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>RNA polymerase sigma-54 factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">rpoN</name>
        <name type="synonym">ntrA</name>
        <name type="ordered locus">AZC_3925</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1993" name="Mol. Plant Microbe Interact." volume="6" first="238" last="252">
            <title>Azorhizobium caulinodans nitrogen fixation (nif/fix) gene regulation: mutagenesis of the nifA -24/-12 promoter element, characterization of a ntrA(rpoN) gene, and derivation of a model.</title>
            <authorList>
                <person name="Stigter J."/>
                <person name="Schneider M."/>
                <person name="de Bruijn F.J."/>
            </authorList>
            <dbReference type="PubMed" id="8471796"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sigma-54 factor family.</text>
    </comment>
    <dbReference type="EMBL" id="X69959">
        <property type="protein sequence ID" value="CAA49582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S33580">
        <property type="entry name" value="S33580"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172445.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P33984"/>
    <dbReference type="SMR" id="P33984"/>
    <dbReference type="STRING" id="438753.AZC_3925"/>
    <dbReference type="EnsemblBacteria" id="BAF89923">
        <property type="protein sequence ID" value="BAF89923"/>
        <property type="gene ID" value="AZC_3925"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3925"/>
    <dbReference type="eggNOG" id="COG1508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020569_0_0_5"/>
    <dbReference type="OMA" id="VTTQKFM"/>
    <dbReference type="OrthoDB" id="1906842at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
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    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIGMA54_1"/>
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    </dbReference>
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        <property type="entry name" value="SIGMA54_2"/>
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        <property type="entry name" value="SIGMA54_3"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0238">DNA-binding</keyword>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0731">Sigma factor</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0805">Transcription regulation</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000205522" description="RNA polymerase sigma-54 factor">
        <location>
            <begin position="1"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="52"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RPON box">
        <location>
            <begin position="480"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA49582." evidence="3" ref="1">
        <original>H</original>
        <variation>L</variation>
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1"/>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="514" mass="55888" checksum="FEE25CA7530F1481" modified="2008-02-26" version="2">MAMSPKMEFRQSQSLVMTPQLMQAIKLLQLSNLELVAYVEAELERNPLLERASEPESPEHDPPNPQEEAPTPPDSGAPVSGDWMESDMGSSREAIETRLDTDLGNVFPDDAPAERIGAGSGSGSSIEWGSGGDRGEDYNPEAFLAAETTLADHLEAQLSVAEPDPARRLIGLNLIGLIDETGYFSGDLDAVAEQLGATHDQVADVLRVIQSFEPSGVGARSLSECLALQLRDKDRCDPAMQALLDNLELLARHDRNALKRICGVDAEDLADMIGEIRRLDPKPGLAYGGGVVHPLVPDVFVREGSDGSWIVELNSETLPRVLVNQTYHATVAKAARSAEEKTFLADCLQSASWLTRSLDQRARTILKVASEIVRQQDAFLVHGVRHLRPLNLRTVADAIGMHESTVSRVTSNKYISTPRGVLEMKFFFSSSIASSGGGEAHAAEAVRHRIKSLIEAESADDVLSDDTLVQKLKDDGIDIARRTVAKYRESMNIPSSVQRRREKQALRSDAAAAG</sequence>
</entry>
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        <submittedName>
            <fullName evidence="2">Putative methyltransferase</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1143</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169674.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1143"/>
    <dbReference type="EnsemblBacteria" id="BAF87141">
        <property type="protein sequence ID" value="BAF87141"/>
        <property type="gene ID" value="AZC_1143"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1143"/>
    <dbReference type="eggNOG" id="COG4106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1208797_0_0_5"/>
    <dbReference type="OMA" id="NSVAQYM"/>
    <dbReference type="OrthoDB" id="1106177at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="44"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="228" mass="24664" checksum="73EE4C63F4E0406F" modified="2007-12-04" version="1">MDWVTFWDGAHSIYVNDRHKMVHYQRITADIVSLIPDPSSRVMDYGCGEALGAPTLADNCAQLILADAAPTVRATLKDRLGGEPNISVLSPEETAELPPASLDLIIANSLLQYISKADLKALLAQWRGLLAPGGAVILADVIPPNVSAVQDAAALLTFGAREGFFFSALLGLARTAVSPYRKLRADLGLTTYEEGEMITLLRGAGYLPQRLPKNIGHNQRRMAFRAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRJ1</accession>
    <name>A8HRJ1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1196"/>
    <dbReference type="EnsemblBacteria" id="BAF87194">
        <property type="protein sequence ID" value="BAF87194"/>
        <property type="gene ID" value="AZC_1196"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1196"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_5"/>
    <dbReference type="OMA" id="MFPFGRI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="270" mass="28608" checksum="3A175222F30FCB30" modified="2007-12-04" version="1">MLPAVQTRRCTAASSLPKVRTMVAVSNQPPRIMLLTGASRGIGHATVKRFSSAGWRVITCSRQPFPEQCPWAAGPEDHIQVDLGNPDDTLAAVEEIKNRLPNGELHALVNNAGISPKGEGGSRLGTLDTPHDVWMQVFQVNFFASIMLARGLVSELEKAQGSVVNVTSIAGSRVHPFAGAAYATSKAALAALTREMAADFGPRGVRVNAIAPGEIDTAILSPGTDKIVAQIPLRRLGTPDEVAKIIYVLCTETSSYLNGAEILINGGQHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRK7</accession>
    <name>A8HRK7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1204</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169735.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1204"/>
    <dbReference type="EnsemblBacteria" id="BAF87202">
        <property type="protein sequence ID" value="BAF87202"/>
        <property type="gene ID" value="AZC_1204"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1204"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_11_1_5"/>
    <dbReference type="OMA" id="YAGCEAG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="246"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="402" mass="42958" checksum="2DE509EB1AAE5A8D" modified="2007-12-04" version="1">MVTLDFQTIGFAAVVLATLMGALLLLAWAYVRSETCLIFWGVTDLFCAGSVAVLTAANGRLGPNVAPFSNGWLLTGAALTYCGMRAFDRRPITLPIWLAVIATPLFYYIACVLFLPNVNDRVVLYTFICCCWFGGSAYVLAHVPSYAPAFSRMLVALFLAGMCTIQVVRLAGSLAGFRPLGGDMTSEQMAWTFAAGLFFTVGLNFGGMFMVLDRMASCDELTELSNRRSLLMGASALLRSALASGRPVSVLLVDLDHFKSINDRFGHRTGDQVLRAFAQVARKLLRRGDLVGRYGGEEFCLVLKDAGSDVACVMAERLRRQVMDDLREVEGHAVEATVAIGVASLEAGQRVAGIDRMIDAADHALYAAKDGGRNRVVLAAPLVTPQPAAPHAGGAAASTGVA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRT6</accession>
    <name>RL27_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmA</name>
        <name type="ordered locus">AZC_4093</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172613.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HRT6"/>
    <dbReference type="SMR" id="A8HRT6"/>
    <dbReference type="STRING" id="438753.AZC_4093"/>
    <dbReference type="EnsemblBacteria" id="BAF90091">
        <property type="protein sequence ID" value="BAF90091"/>
        <property type="gene ID" value="AZC_4093"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4093"/>
    <dbReference type="eggNOG" id="COG0211">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095424_4_1_5"/>
    <dbReference type="OMA" id="GKDHTLH"/>
    <dbReference type="OrthoDB" id="1904463at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000072542" description="50S ribosomal protein L27">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="89" mass="9591" checksum="19DA6AA97A1B5DE3" modified="2007-12-04" version="1">MAHKKAGGSSRNGRDSDGRRLGVKKFGGQAVVSGNIIVRQRGTKWHPGTNVGMGKDHTLFALVEGRVEFRTKANDRTYVSVVPALEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSE9</accession>
    <name>A8HSE9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
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                <person name="Liu C.T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0840"/>
    <dbReference type="EnsemblBacteria" id="BAF86838">
        <property type="protein sequence ID" value="BAF86838"/>
        <property type="gene ID" value="AZC_0840"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0840"/>
    <dbReference type="eggNOG" id="COG3170">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_443244_0_0_5"/>
    <dbReference type="OMA" id="RWFEREV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="647" mass="72094" checksum="FF4E3EADAF7D4160" modified="2007-12-04" version="1">MSDSALSGAGESMIGAPDDMDMRRFRAWFQMDAAHSHKWRPAAREWYAFVAGDQWSSEEKAALESQQRPAIVFNRSLSIIKAVAGSEINGRQEIHYLPRTLDDAGVNEALTGASKYFADQAGAEDEESDAFQDSLICGMGWTEQRLDNTENPEGDYVEDRIDPLEMFWDRSAKKRNLADARRVCRVRKIPISDARDMFPGFTDAELDATWADAGELIDPNKTVEQKRVRDGNYDAFSLDDDRSEVTLVEFQWWEKERYFIAADPATGQRIELSAKEHDVLSGRLSKLGVQLNSASATRKVYKRAFIGSVVLEVSTPPTGNTFSYACITGERDRNAGTWFGLMQLMRDPQKWANRWLQQALHIMNTNAKGGLLAEEDAFEDQRDAEETWARPDAITWLRKGALSSVNGAKVQPKPQTGIPAGYYQLLEFAISSIRDVTGINLELLGMRDANQPGILEAQRKQAAMTILATAFDSLRRYRKVIGKQRLYFIQNFLSDGRLVRILGRDGTERVIPLMRDTTVGEYDVVIDDAPSAPNQKEANWAIISQMLPLVGPMMTPELWLAVLEYSPLPSALVEKLKTLIPAQGEASPEQKQQAMVALQSALAKIKVDETTAAKNAASAAQSHASAEKTQIEAARLMRQPIGIPALQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU60</accession>
    <name>ISPE_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4-diphosphocytidyl-2-C-methyl-D-erythritol kinase</fullName>
            <shortName evidence="1">CMK</shortName>
            <ecNumber evidence="1">2.7.1.148</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ispE</name>
        <name type="ordered locus">AZC_0910</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57823"/>
            <dbReference type="ChEBI" id="CHEBI:57919"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.148"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GHMP kinase family. IspE subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.148" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169441.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HU60"/>
    <dbReference type="SMR" id="A8HU60"/>
    <dbReference type="STRING" id="438753.AZC_0910"/>
    <dbReference type="EnsemblBacteria" id="BAF86908">
        <property type="protein sequence ID" value="BAF86908"/>
        <property type="gene ID" value="AZC_0910"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0910"/>
    <dbReference type="eggNOG" id="COG1947">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053057_1_0_5"/>
    <dbReference type="OMA" id="RWPSPAK"/>
    <dbReference type="OrthoDB" id="1938933at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00094"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050515">
        <property type="term" value="F:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00061">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004424">
        <property type="entry name" value="IspE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43527:SF2">
        <property type="entry name" value="PTHR43527:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010376">
        <property type="entry name" value="IspE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00154">
        <property type="entry name" value="ispE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000335701" description="4-diphosphocytidyl-2-C-methyl-D-erythritol kinase">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00061"/>
        </source>
    </evidence>
    <sequence length="289" mass="30258" checksum="23F35E6BCF04D73F" modified="2007-12-04" version="1">MQRLVARAPAKVNLTLRILRRRPDGFHDLASIVAFAGACDVVTLESDAPLGLAVAGPSAAAAGPDADNLILRAADAFARHVPGARLGRFTLTKRLPVAAGIGGGSSDAAAALRLLAQINDIALDDPRLHAAAREVGADVPVCLDPQARIMEGIGERLSEPLGLAPLFAVLVNCRVPVPTADVFRTLGLRAGEDLAGLPHEAPMSTGRAAVMRHLVLHGNDLEPPAETVAPEITRVKAMLAQEPEVRLVRMSGSGATVFALTDDCRAAAQVARRVAAAEPGWWVRPTVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUP8</accession>
    <name>A8HUP8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0970</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0987"/>
    <dbReference type="EnsemblBacteria" id="BAF86985">
        <property type="protein sequence ID" value="BAF86985"/>
        <property type="gene ID" value="AZC_0987"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0987"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_033863_4_4_5"/>
    <dbReference type="OMA" id="WANEYVS"/>
    <dbReference type="OrthoDB" id="1515911at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
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    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="60"/>
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            <end position="127"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="162"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="193"/>
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            <begin position="258"/>
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        </location>
    </feature>
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        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
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            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="165"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="308" mass="33256" checksum="7AE340DFDEC0511D" modified="2007-12-04" version="1">MSVRAAQSPLAAIANAPYLLLSFTALLWAINMVIGRYMVGAVPPITTACVRWLLATLILLPFAWRQIVRDAPLLRRHFWRLVLLSSTGIASYNAMSYYGLQYTQALNGLLLQSISPLLVAVWSLLLFRDGLSLGQTVGVFISLAGVLIIISGGSIDTLLHLTLNAGDIWIMVALAIYAFYTAILRVRPPLGPLSFLAAIMAIGGVLLLPVMAWELTHGAELHFNRFTLGVFAYVSTAPSLLAYLAFNRGVQLVGANRAAPFFHLMPVFGTALAILFLGETFAWFHAAGYALVLTGILTATRAKGAKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV21</accession>
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        <submittedName>
            <fullName evidence="4">CobW protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cobW</name>
        <name evidence="4" type="ordered locus">AZC_1001</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169532.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1001"/>
    <dbReference type="EnsemblBacteria" id="BAF86999">
        <property type="protein sequence ID" value="BAF86999"/>
        <property type="gene ID" value="AZC_1001"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1001"/>
    <dbReference type="eggNOG" id="COG0523">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017452_0_2_5"/>
    <dbReference type="OMA" id="HDVNRHD"/>
    <dbReference type="OrthoDB" id="1267701at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="3">
        <location>
            <begin position="270"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="392" mass="41930" checksum="5455F03EC2568E75" modified="2007-12-04" version="1">MSPFETPEAGTAPDRPARRGPPEPIPVTVLTGFLGAGKTTLLNRILADTALADTAVLINEFGEIGLDHLFVREVDEGVVLLASGCVCCTVRGDLVAALEDLLRGRDNNRLPPFSRVLIETTGLADPAPILHTLMTHPYLLMRYRLDGVVTVVDAINGGATLDAQPEAVKQAAVSDRIVLTKTDLAQTDAEKTAVADLRRRLATLAPAAPVLDAAAGEATAERILKAGLYDPARKIPDVARWLAEEQIAANREAAEGPAVVTDPNRHDDRIKAFSLATDAAIPASTLDLFLELLRATHGGSVLRMKGIVKLADDPSAPVVLHGVQHVMHPPSRLAAWPDDDHRTRLVMIVRDLDPMVIQRLFEAFLGVPSVDTPDRAAMTDNPLAPPGLSGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV69</accession>
    <name>A8HV69_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4280</name>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
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            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF90278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4280"/>
    <dbReference type="EnsemblBacteria" id="BAF90278">
        <property type="protein sequence ID" value="BAF90278"/>
        <property type="gene ID" value="AZC_4280"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4280"/>
    <dbReference type="HOGENOM" id="CLU_2876034_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="63" mass="7234" checksum="6E4ED552B8217781" modified="2007-12-04" version="1">MERVHDLGPALICTRFLFHAGHLSTSEQRRKSVVQERESSLARRIVFATSQAKGTRPSERNKR</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
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        <recommendedName>
            <fullName evidence="3 5">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="2 5">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_4312</name>
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    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the fabD family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="2 5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172832.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4312"/>
    <dbReference type="EnsemblBacteria" id="BAF90310">
        <property type="protein sequence ID" value="BAF90310"/>
        <property type="gene ID" value="AZC_4312"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4312"/>
    <dbReference type="eggNOG" id="COG0331">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030558_0_1_5"/>
    <dbReference type="OMA" id="AANYNCP"/>
    <dbReference type="OrthoDB" id="1123553at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="7">
        <location>
            <begin position="6"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="318" mass="32349" checksum="D21D29C91E55F8CC" modified="2007-12-04" version="1">MSTAFIFPGQGSQAVGMGKALAENFAAARDVFTEVDAALGEHLTRIMWEGPADELTLTANAQPALMATSLAALRVLEAEAGLNLARDAAFVAGHSLGEYSALAAAGTFTISDAARLLRIRGRAMQDAVPAGAGAMAALLGLDYEQAVAVAAEAAGDDVCEAANDNAGGQVVVSGSLKAVERAIEIAKAKGASRAILLPVSAPFHCRLMEPAAEAMAAALAEVEVKAPVVPVISNVRASPVTDPAEIVRLLVEQVTGTVRWRESVVYMAGAGVSRAVEVGAGKVLSGLVRRIAKEIQVSAVGTPEDVAAFIATKAAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="3">Penicillin-insensitive murein endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4326</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="5">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="5">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="5">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="5">
        <citation type="journal article" date="2009" name="PLoS ONE" volume="4" first="E4695" last="E4695">
            <title>A novel endo-hydrogenase activity recycles hydrogen produced by nitrogen fixation.</title>
            <authorList>
                <person name="Ng G."/>
                <person name="Tom C.G."/>
                <person name="Park A.S."/>
                <person name="Zenad L."/>
                <person name="Ludwig R.A."/>
            </authorList>
            <dbReference type="PubMed" id="19277114"/>
            <dbReference type="DOI" id="10.1371/journal.pone.0004695"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="5">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="7">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="5">ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="FJ378904">
        <property type="protein sequence ID" value="ACJ13745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4357"/>
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        <property type="gene ID" value="AZC_4357"/>
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    <dbReference type="KEGG" id="azc:AZC_4357"/>
    <dbReference type="eggNOG" id="COG0651">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="VITWASA"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
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        <property type="entry name" value="ND/Mrp_mem"/>
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        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="NUOXDRDTASE4"/>
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    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="25"/>
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        <location>
            <begin position="32"/>
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            <end position="122"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="180"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <end position="220"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
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    <feature type="transmembrane region" description="Helical" evidence="2">
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    <feature type="transmembrane region" description="Helical" evidence="2">
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    <feature type="transmembrane region" description="Helical" evidence="2">
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            <dbReference type="RuleBase" id="RU000320"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
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    </evidence>
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            <dbReference type="EMBL" id="ACJ13745.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="481" mass="50433" checksum="6E4AB4F1A46928F0" modified="2007-12-04" version="1">MTLGLDAASALLLLPAASALLLLVLPAPRLGAWLNAASAALSFVAAASLLLVQPPEGEFLRVDDLNIVFLVLNSFVGATTSLYSAGYIAHELETGRLSPAQMRVYHAMYQVLLFAMNLALLASNLGVMWVAIELATLTTVLMVGLYRTPAAIEAAWKYFILGSVGIALALFGTILVYMAARPVVGEGHDGMLWTVLMSHAAAFDPALLNLAFVFLLLGYGTKVGLVPLHSWLPDAHAEGPTPISAVLSGLLLNVALYAVLRFKLLLAAAPGALAPGPLLMGLGLLSLLFAGLMLYRRRDIKRLFAFSSIEHMGLIAFAFGIGGPVANFAGLLHMVMHSLTKSAIFFGVGHAVQVKGTQALSEIRGLTASHPLLGWGLVAGVAAIVGLPPAGVFMSEFLILTSTVARAPVLAGLLALGLVIAFAALMLRLHALAFGAPRGPSAPVKGTQVPMLVHLALVWCAGVWLPGPLVSWFQHIAHLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <begin position="14"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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        <source>
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        <source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87422.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="916" mass="98738" checksum="2F4761FA1DAFD2DA" modified="2007-12-04" version="1">MPAIHDVDRGEQRRALAMSTVSFTVCFAVWTIFSIIGISIRKELGLSETQFGLLVGTPILTGSLIRVVLGIWTDRYGGRLVFTATMLAAAAATFLLSHATTYPQMLAAALGVGIAGGSFAVGVAYVSRWYPAGKQGTALGIFGAGNVGSAVTKFLAPFVLVAFGWQMVAQVWAAALVVMAAIFWFTTNDDPVQAERRRTGLRPKSAWLELEPLKNVQVWRFAIYYFFVFGAFVALALWLPQYLINVYGLDIKTAGMIAAFFSVPASLFRAYGGHLSDVYGARRVLYWTFLVGIAATFVLSYPPTDYVVHGTNGPIAFHMEMGLVGFTVSVFVLGFFMALGKAAVYKHIPVYYPDHVGSVGGLVGMIGGLGGFVLPILFGVLLDLTGLWTSCFMALFLLVSGALVWMHLAVRQMEREAGGETLARLPQLPEMQGLPEPKVTAVPPKASGAVLTDWRPEDPEFWAKTGRAIARRNLWLSIPALLLSFAIWQVWSVVVAKLPLVGFTYSTDQLFWLAALPGISGATLRIFYSFMVPIFGGRLWTTLTTWSLIIPALGIGYAVQNPDTPYVVLLILALLCGFGGGNFSSSMANISFFFPKAEKGNALALNAGLGNLGVSVVQFVVPLVITAGVFGWLGGDPAMVKGQAAPLWLQNAGFVFVPFIVLSAFASWFGMNDIADAKASFAEQAVIFRRAHNWIMCWLYTGTFGSFIGYSAGFPLLAKALFPDVNALQFAFLGPLVGALSRSGTGWLADKYGGARVTMGAFVLMMIGVSGVLWFIGIRDQSGAFWGFFASFLLLFFATGVGNASTFQMIPAIMTKEMARLMPKADAEARRKQAEKESAAITGFTAAIAAFGAFFIPKGYGTSIALTGGPEAALWGFLIFYVSCLVLTWAVYTRKGGLLHDVERAKRASIRPAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWY1</accession>
    <name>A8HWY1_AZOC5</name>
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        <name evidence="5" type="ordered locus">AZC_1440</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1440"/>
    <dbReference type="EnsemblBacteria" id="BAF87438">
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        <property type="gene ID" value="AZC_1440"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1440"/>
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    <dbReference type="OMA" id="QTTFHYA"/>
    <dbReference type="OrthoDB" id="538961at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="Leu-bd"/>
    </dbReference>
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        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
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        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LEUILEVALBP"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723959" evidence="3">
        <location>
            <begin position="25"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="4">
        <location>
            <begin position="26"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="394" mass="41593" checksum="31E1E1D05D4F3096" modified="2007-12-04" version="1">MRTRIIATALALALSAGASATALAETVKVGVIGPFSGPFALQGKNFKAGIDAWFATHGNKVGNDTIEVIYRDVPQPDPAQSKSAAQELVVKEKVQYLAGFYFTPDAMAVTPILKQANVPMVVMNAATSAIVTKSPLVVRTSFTTWQTSTPMAKVAYDQGIRKVISVVSDYGPGVDAENAFKTAFTALGGQVVETVRMPLSTNDFSPIMQRVKDSGAQAVFAFLPSGPTTLGFVKAFNENGLKSGGIKLLAPGDLTQESDLPALGDAALGMLTTFHYSVAHDSPENKAFVEAARKAIGNPVELSFPAVAAYDGMYVITKMIAATGGKPDAQKAVDAVKGLAWVSPRGPVSIDAESRHITENIYLREVAKAADGTYYNKEIATFEKQDDPGLKAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWZ0</accession>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169971.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1443"/>
    <dbReference type="EnsemblBacteria" id="BAF87441">
        <property type="protein sequence ID" value="BAF87441"/>
        <property type="gene ID" value="AZC_1443"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1443"/>
    <dbReference type="eggNOG" id="COG3485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027719_5_0_5"/>
    <dbReference type="OMA" id="YRWDIVL"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018578">
        <property type="term" value="F:protocatechuate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019619">
        <property type="term" value="P:3,4-dihydroxybenzoate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03464">
        <property type="entry name" value="3_4-PCD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024756">
        <property type="entry name" value="PCDO_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012785">
        <property type="entry name" value="Protocat_dOase_b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12391">
        <property type="entry name" value="PCDO_beta_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02422">
        <property type="entry name" value="protocat_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCDO_beta_N" evidence="5">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="INTRADIOL_DIOXYGENAS" evidence="4">
        <location>
            <begin position="53"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="249" mass="28090" checksum="215D6B7A11628E7E" modified="2007-12-04" version="1">MSEQSNRRPETGAFFARDRAWHAPAYTPTYKTSVLRSPQRALLSLDGTLSETTGPVFGHSLLGALDNDLIHNYARPGESAIGERIIVHGRVLDERARPVAGALVEFWQANAGGRYRHKKETYLAAIDPNFGGCGRAITDEDGRYFFRTIKPGPYPWPNGVNDWRPAHIHFSIFGHGFAQRLITQMYFEGDPMIWKCPIVNTIPDKAAIEQLIAPLDWGNTIPMDARAYKFDIVLRGRRSTMFENRMEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX61</accession>
    <name>A8HX61_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Putrescine-binding periplasmic protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1465</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the activity of the bacterial periplasmic transport system of putrescine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial solute-binding protein PotD/PotF family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169993.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1465"/>
    <dbReference type="EnsemblBacteria" id="BAF87463">
        <property type="protein sequence ID" value="BAF87463"/>
        <property type="gene ID" value="AZC_1465"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1465"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_1_4_5"/>
    <dbReference type="OMA" id="SNWTEYM"/>
    <dbReference type="OrthoDB" id="1264541at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019574">
        <property type="entry name" value="Periplasmic_polyamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0574">Periplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723136" description="Putrescine-binding periplasmic protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR019574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="368" mass="41189" checksum="8DCE976247C7B1FF" modified="2007-12-04" version="1">MRRFVLAAVLGAAAIVAGPALAQQKVVNVYNWSDYIDESVLEEFTKETGIKVRYDVFDSNEVLETKLLAGKTGYDVVVPSGSFMQRQIKAGVFIKLDKSKLPNLQYAWPEITKRLAVYDPGNEYAVNYMWGTTGIGYNVDMVKQRLGDVPMNTWDIVFKPENLSKLKDCGVYMLDGPEEIIPTAMRYLGLDPDSKKPEDITKAGELLMKIRPFIRKFDSSGYINALARGDICLAVGWSGDVFQAKARAEEAAKKTKKKVVPVAYALPKEGALMWFDNFAIPKDAKNIDEALTFINFMMRPEIAAKNSNFISYANGNLASQKFIDKAVLDNPAIYPTPEVFALLFTVTTNPQDVQRVITKTWNTFKRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX81</accession>
    <name>A8HX81_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">uspA</name>
        <name evidence="3" type="ordered locus">AZC_1471</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169999.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1471"/>
    <dbReference type="EnsemblBacteria" id="BAF87469">
        <property type="protein sequence ID" value="BAF87469"/>
        <property type="gene ID" value="AZC_1471"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1471"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_5_2_5"/>
    <dbReference type="OMA" id="ACKREGV"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="155"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="277" mass="29234" checksum="8A33EFEAB29643D8" modified="2007-12-04" version="1">MIRDILVNLSLGSERDPAAVYAASLAAACKAHITGLAVSYEIDVPPFYMGALPTDFIDQQIRENEAAATTAAGAFTALAREHGLSYDVRTLSGSLGDAAAAVGDLSRLYDLTVVAQPDPDRPGPEEVLAESALMDSGRGVLVVPYVQKPPFSLSRVVVAWDGSRASARALAESLPLLHMADSRVIFSVRRSENEEATPNAADLERHLAHHGLSAELRHLTIGSGESISSAILNEVSDQGADLVVMGGYGHSRVRELVFGGVTRDILGSMTAPVLLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXE2</accession>
    <name>A8HXE2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitooligosaccharide deacetylase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1491</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170019.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1491"/>
    <dbReference type="EnsemblBacteria" id="BAF87489">
        <property type="protein sequence ID" value="BAF87489"/>
        <property type="gene ID" value="AZC_1491"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1491"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_1_1_5"/>
    <dbReference type="OMA" id="RSRIWIL"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0536">Nodulation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="64"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="302" mass="34296" checksum="E7222E7908137BB5" modified="2007-12-04" version="1">MTKTVANPAGEPWQWEEAHWRGLINQVRAGERLAPKNWPGGARCAVALSFDADHETNELRDGGKSIGRMAWGQYGNRVGVPRVLELLKRHDIPASFYVPAVVALTYPDEQRRVIAEGHEIGIHGWIHELNSVLPYEVERDLMFRAADTLEHVTGVRPVGLRTPSWDFSPNTLRIETELGLLYDSSLMADEDCYDLLMDGVSTGIVEVPVEWIRDDAVYFMMHRFQSLRPYTPPKDVLDIFLREFDAAYEAGGLFQLTMHPHIITPRSRIWILEEVIRHAKAKGDVWFATHAQVAEYAKANKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXW7</accession>
    <name>A8HXW7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1548</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170076.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1548"/>
    <dbReference type="EnsemblBacteria" id="BAF87546">
        <property type="protein sequence ID" value="BAF87546"/>
        <property type="gene ID" value="AZC_1548"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1548"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024588_2_1_5"/>
    <dbReference type="OMA" id="IWPHGRW"/>
    <dbReference type="OrthoDB" id="829830at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010158">
        <property type="entry name" value="Amidase_Cbmase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32494">
        <property type="entry name" value="PTHR32494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001235">
        <property type="entry name" value="Amidase_carbamoylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01879">
        <property type="entry name" value="hydantase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="4">
        <location>
            <begin position="216"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001235-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="419" mass="44185" checksum="1BB522FE5B242BC2" modified="2007-12-04" version="1">MSEKPSNLPVNSDRLWGTILETAAFGATPKGGVRRLTLSQEDRKVRDWFKAACEAAGCTVTVDALGNMFALRPGRDPSRAPIGLGSHLDTQPTGGKFDGILGTLAALEVVRTLNDAGIETEAPLCVANWTNEEGSRFAPAMMGSAAFVGDFTVENILGRKDAEGVTVKEALEAIGYVGAAPVGSQPFEAFVELHIEQGPILEAENKTIGVVEHGQGIVWYDGHITGFESHAGSTPMPLRRDALATFSQIVLAVEAIARKHGPDAVGTVGEVTIANPSRNVIPGEVNFTCEFRSPHAEILKALEADFAAAVTEIAAGRKGVTVEIEQVWRKDPTHFDPKVIGAIREAAEGLGYSNRPMVSGAGHDAFNLATRMPVAMIFVSCKDGLSHNELEDATQADCTAGANVLLHTVLSLAGVANAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYJ0</accession>
    <name>A8HYJ0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="12">ABC transporter nucleotide binding ATPase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_1621</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1621"/>
    <dbReference type="EnsemblBacteria" id="BAF87619">
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    <dbReference type="eggNOG" id="COG1132">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000270">
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC1_TM_dom"/>
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        <property type="entry name" value="ABC1_TM_sf"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
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    </dbReference>
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        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="31"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="347"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="380"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF87619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="587" mass="64476" checksum="AFBFAE99C8F7E43D" modified="2007-12-04" version="1">MTRPAAPPHGSIMSLLRAFFAYYRPYKGLFLLDFTCAVVSGLLELGFPMAVKLFVDQLLPGQEWGLIAAAAAALVGIYLLNAALMAIVTYWGHMLGINMETDMRRRAFDHLQKLSFHFFDNQKTGHLVARITKDLEEVGEVAHHGPEDVFIAIMTFIGAFALMMMVNVHLALITGAIVPVVAWLGAHYGSRMTENFRALFGRVGDFNARIEENVGGIRVVQAFANEAHERALFAKDNERYRATKLAAYRIMAANMTLNYLGMRLTQVMVMIAGTWFVIRGELSNGGFISFLLLVGVFFRPIEKINAVLEIYPKGLAGFRRYLDLLDTAPDVADRPGARPLTGLKDAIRYEHVSFGYGEGKSVLNDLSLTIRAGETVAFVGPSGAGKTTICSLLPRFYEPTAGRITIDGTDIRDFTLASLRSHIGIVQQDVFLFAGTLRENIAYGRLGATEEDILNAARRARLDGLIAALPAGLDTIVGERGVKLSGGQKQRVAIARIFLKDPPILILDEATSALDTETELEIRQSLAALSEGRTTLTIAHRLSTIRNADHIIVVSPEGIAEQGRHGDLVARDGLYRRLHDTQFADMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYJ7</accession>
    <name>A8HYJ7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SpoU rRNA methylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_4469</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172988.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4469"/>
    <dbReference type="EnsemblBacteria" id="BAF90467">
        <property type="protein sequence ID" value="BAF90467"/>
        <property type="gene ID" value="AZC_4469"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4469"/>
    <dbReference type="eggNOG" id="COG0566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021322_3_3_5"/>
    <dbReference type="OMA" id="GYHVHRG"/>
    <dbReference type="OrthoDB" id="1422015at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="4">
        <location>
            <begin position="135"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="281" mass="29358" checksum="C2030EEB0579F5D9" modified="2007-12-04" version="1">MSSLATASLPAHEPLRLIPVSDPDDPRIADYRDVRERDLVGRRGLFMAEGEVVLRLLTAHGGRDLHSVLVSQASLPRIADALDLLPRNVPVHVAGQAVMDAIVGFHIHRGILAVGRARPQVPAPELLASLPERALVVALQGIANHDNMGGIFRNAAAFGADAVLLDSACCDPLYRKAIRVSVGASLIVPTARAGTTAEMMEAIAAAGFDLVALSPSGRERLSDIVPGGRQAALFGTEGPGLPPEVLASTRTISIPMAASFDSLNVATTSGIVLHHLSRTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ30</accession>
    <name>A8HZ30_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Lee KB."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169855.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1327"/>
    <dbReference type="EnsemblBacteria" id="BAF87325">
        <property type="protein sequence ID" value="BAF87325"/>
        <property type="gene ID" value="AZC_1327"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1327"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049704_2_0_5"/>
    <dbReference type="OMA" id="YFNRTFR"/>
    <dbReference type="OrthoDB" id="1785082at2"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="211"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="316" mass="34575" checksum="56A5B27043997C9E" modified="2007-12-04" version="1">MAGRYDPAWFTTAGLPPRRGQDAAVKLFADLLGDVSLHFGAANGRPARIVHCALPDILITTCVDVRAVIRSERGMVPSDIILVRPVGGRIGLRQAGREIWLEERSAALVALGHPFELDATRAERFDFLRMAAPVAAHAEALHGRIAKPAPASDNRLMLLTHYAGAVLQGMIPLDSERHARLAGNHLRDLAGTLFGLDDPAQGALSPAVRLAAIRYQVDRDYARRDLSVESVARLHGVTGRYVQKLFAQEGTTFSRYLLERRLAAAHALLTSEEGPRARIATVALEAGFGDLSYFVRTFRTRYGAPPSHISKRERPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1Y1</accession>
    <name>A8I1Y1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4678</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173197.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4678"/>
    <dbReference type="EnsemblBacteria" id="BAF90676">
        <property type="protein sequence ID" value="BAF90676"/>
        <property type="gene ID" value="AZC_4678"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4678"/>
    <dbReference type="eggNOG" id="ENOG502ZRPY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1700641_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="154" mass="16338" checksum="FBAD200F535D0C57" modified="2007-12-04" version="1">MNRTLRAFLIAPLWAPALTGLQMFLFGLPRSMGPLDPTEWLLLSLVLSLLLGCAGVWTLGVLIHRLLAARRITALWRHIAIWFAAGLAVRMLLLVATWAPTGGLAFGLSELQGAMQTRPLFLLSGGLAGALMGGTIWLMAGIGRPGALGPSSAK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8I266</accession>
    <name>MNMG_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mnmG</name>
        <name evidence="1" type="synonym">gidA</name>
        <name type="ordered locus">AZC_4709</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MnmG family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173228.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF87825">
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        <property type="gene ID" value="AZC_1827"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1827"/>
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        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50943"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="231" mass="25103" checksum="E578A91188797B52" modified="2007-12-04" version="1">MLAPCRSLPLSSEETDKCSVKGSVMAQREKPPERGSGLEPGAHAITGQLGKTIQRLRKAYNLSLSDLAEQSGVAKSIISQIERNETNPTLATVWRLSQALDVTVERVLASSDEAPFVEKLTRADTPMLQSEDGLCRLAIIGWIKTVEWLQYYDFHAEPGGVLDSEGHQLGSIECLSVLEGELEVEVGGVIETAKAGETLRYRCDRQHVIRNVGGGHAHALMVCLLKAAVLD</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1895"/>
    <dbReference type="EnsemblBacteria" id="BAF87893">
        <property type="protein sequence ID" value="BAF87893"/>
        <property type="gene ID" value="AZC_1895"/>
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    <dbReference type="KEGG" id="azc:AZC_1895"/>
    <dbReference type="eggNOG" id="COG0583">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
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    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="entry name" value="HTH_LYSR"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="300" mass="33331" checksum="623434CD0AC50D63" modified="2007-12-04" version="1">MQVPLRAIGVFHAVARTGSVTRAADELGVTPSAVSQQVQALEISLGTALIGKAGRNVVLTEAGERYFEMIRGEVERITEATQRIRGFRSVTTLTVRATPSLATKWLLPRLAGFIDAHPEIELRLDGTNEPTAFQKENVDVEIRHGTGQWPGLVAEGLVEERFLPVCSPALAAAGSLAAEDLPRFRLIHSVKSQVQWPYWFTCAGVTPAERLRRLFFDRTHMAIDAAVGGLGIALESDLMMWAEKHDGRLICPIAEPPRITLVTQWATCPPDHLRHSKVKLFFDWLRRERDNWLATRDASL</sequence>
</entry>
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    <accession>A8I2N5</accession>
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            <fullName evidence="4">Acetoin dehydrogenase complex E2 component protein</fullName>
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        <name evidence="4" type="ordered locus">AZC_1907</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1907"/>
    <dbReference type="ESTHER" id="azoc5-a8i2n5">
        <property type="family name" value="AcoC_BiotinLipoyl-ABH"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87905">
        <property type="protein sequence ID" value="BAF87905"/>
        <property type="gene ID" value="AZC_1907"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1907"/>
    <dbReference type="eggNOG" id="COG0508">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_13_2_5"/>
    <dbReference type="OMA" id="QIHTLTM"/>
    <dbReference type="OrthoDB" id="1119700at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
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        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="LIPOYL"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="3">
        <location>
            <begin position="5"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="371" mass="38953" checksum="46156C0CCB8DED58" modified="2007-12-04" version="1">MNARINPIVMPKWGLSMAEGKVTGWLVRPGAKITAGDEILEVETDKIAGVVEAGEAGTLRRVLGEPQTVYPVKALIGVIADDDVPDAEIDAFVAAYAVPAEEGEDAAEAGPRYEFVETPAGRLRYARRGEGEDTVLLIHGFGGDLDNWLFNIDALGAAATVYALDLPGHGQSEKALGDPSLPGLATAVLGFMDALGIARAHLVGHSMGGALAQRVAVDAPSRVASIALIASAGLGPEINGDYIAGFVSAAGRRELKPVLEHLFHDPSTVTRQLVDDVLKYKRIDGVDTALRALADGLFPDGRQASQLADRTRAAGTRTLVVFGEGDRIIPAAHAQALADTAQVHVLPEAGHMVQMEKAGRVNELLLKHIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Akiba N."/>
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                <person name="Aono T."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_2017"/>
    <dbReference type="EnsemblBacteria" id="BAF88015">
        <property type="protein sequence ID" value="BAF88015"/>
        <property type="gene ID" value="AZC_2017"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2017"/>
    <dbReference type="eggNOG" id="COG0388">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="P:nitrogen compound metabolic process"/>
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        <property type="entry name" value="C-N_Hydrolase"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="311" mass="34664" checksum="0A15A98EEDEB3AF9" modified="2007-12-04" version="1">MSRILTVAAAQLGPIQRADTRASVVRRLCDLLRQAAGHGCDLVVFPELALTTFFPRWYTEDQTEIDAFFETALPSAETAPLFALAGALKVGFCLGYAELVEEDGRLRRFNTSVIVDKSGEIVLKYRKIHLPGHAEHEPWRAFQHLEKRYFEVGNLNWPVRRIMGGVLGMAICNDRRWPETYRVMGLKGVEMVLIGYNTPRHNPPAPDHDRLSEFHNQLSMQAGAYQNGTWVVGAAKCGVEEGCEMIGASSIIAPSGQIVAQALTQDDELVLARCDLDMCASYKETTFNFAKHRQPEAYRLIVEQTGAIAPE</sequence>
</entry>
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    <accession>A8I3M5</accession>
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    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1632"/>
    <dbReference type="EnsemblBacteria" id="BAF87630">
        <property type="protein sequence ID" value="BAF87630"/>
        <property type="gene ID" value="AZC_1632"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1632"/>
    <dbReference type="eggNOG" id="COG4774">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_008287_19_1_5"/>
    <dbReference type="OMA" id="QVNIRGM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BtuB-like"/>
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        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011276">
        <property type="entry name" value="TonB_haem/Hb_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TonB-hemin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
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    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="116"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="277"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="752" mass="80750" checksum="246378977F81F3BA" modified="2007-12-04" version="1">MVVESSSFGAMGRGACGGHAAFWKEPMARMHDMARAEHALILINKSLMIGISLATLLAAAPALAQQAASGARSTPATATAPAGNVNGATGGDSQQALPTISVNDAGNSLFGDPYATPAAVSSVDLLNSPGDYERLDDVLRSVPGTFTTQSTSNPGVAVNIRGFQGMGRVNMMIDGVRQNFRFVGHEAGGFTYVDDQLLAGMDIARGAVSTAGGAGALAGAVNMRTLGIDDIIKPGSTWGAIANVQWGSNGQGWQEMVASAVRMNDRFAVGGAVATRDTGNYKNGDGQTVPYTGQDLTSGLLKADMKLTDDSRLKLGAVFYNNFFYADSADQHVRNNTFTGNYSYTPGNDWIDFRLNAYLNDLKMVYGNVPATTSSYRGRVIDDRGWGFDTSNTSRFLLGQVAVATTYGAEYFYDDVSSTNTVTPSLYGGVNPAGTSAIGGVFDETKFNYSIFELIVGLRYDFFNLNGSGYENSMGGAVPVGPWTVDQDKGRFDPKVTFAISPFDWLQPYVTYAETMRAPTASETMIGGEHPGTSVSYSANPYLQPEVSKGWEFGVNIRRNGIFTANDQLRLKADYFTNDIDNYIVTCRKTQYYFCNVAGTSTVSGVEFEAHYDARKVFADLTYTHNTNDLPAQTQGFGANQYLPEDIVTVSAGLRFLEEKLSVGGRYTYVSEGQTLAYNASFLGTVSSTPSPAYNIVDLFSSYAVSDKLTFRFDATNLLNENYTPALSIQPTGFSGDTGQGRTYLLSLRAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3Q5</accession>
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        </submittedName>
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    <organism evidence="10 11">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="3">
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="9 10" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="6">Part of the Bam complex.</text>
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        <text evidence="6">Belongs to the BamA family.</text>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01430">
        <property type="entry name" value="OM_assembly_BamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03303">
        <property type="entry name" value="OM_YaeT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="8">
        <location>
            <begin position="85"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="8">
        <location>
            <begin position="155"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="8">
        <location>
            <begin position="326"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="8">
        <location>
            <begin position="408"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF87699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="857" mass="93789" checksum="C2C8835E289E45C8" modified="2007-12-04" version="1">MAQRSREKRKPLLGRAFAVHGKGCKSASKVENPGVRPWVENNEFKVARHMTAPARVFVKLAAVLGIAFATAVTTTAGSMVVASPAMAQSASIVVQGNRRVDADTIRSYFNLKPGEGLTSAKIDDGVKALYATGLFADVRVSQQGGRTVVTVVENEVINKIAFEGNKKIKDEQLSGEIQSKERGPFSKALVQADTQRIVDLYRRTGRTDVKVNPVTIDRGNGRVDLVFEINEGEKTGVKDIKFVGNKAFSDWKLKDVISTTTTNWLSFLKSTDVYDADRVNADQELLRRFYLKNGYADFRIVSASAELDPGGAGYVITIVLDEGAQYKFGKVDVVSNIRDVPASSLRNALRVSDGQIYNAELVEKTVENLTIEVSKSGYAFAQVRPRGDRDFENKRINVTFVVEEGPRVYVERIEIRGNTRTRDWVIRREFDIGEGDAYNRVLVDRAERRLKNLGYFKTVKITNEPGSAPDRVILVVTVEDQPTGEFSISGGYSTADGFIGSVSLGEKNFLGRGQYVSISGSLGQYSQGAQFSFTEPYFLGYRVAAGFDLYWKETSANSYTVYDSQTIGGGVRLGLPITDEVTLALRYNLYQRELSLPNCTTFYGTALTAQNCGVSWAIIEAVQQGQTITSVVGYTLSFNGLDSNINPTSGLYAELKQDFAGLGGDVNFVRTTGDVRYYYPLIYDSILLLHGQAGYVSAWGGKDLQIMDNFFMGPNLVRGFAPSGIGPRDLANYNQDALGGTTYWGASAEVQFPLSFLPKDVGMKGAVFFDAGSVYGYTGPTTFASAGTANFTVCPSNSQNKMGAICVADDNVIRTSVGASLIWQSPFGPLRFDYAWALTKASYDDLQAFRFSGGTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8I551</accession>
    <name>A8I551_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha-E domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1817</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170345.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1817"/>
    <dbReference type="EnsemblBacteria" id="BAF87815">
        <property type="protein sequence ID" value="BAF87815"/>
        <property type="gene ID" value="AZC_1817"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1817"/>
    <dbReference type="eggNOG" id="COG2307">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071567_1_0_5"/>
    <dbReference type="OMA" id="FWIGRYV"/>
    <dbReference type="OrthoDB" id="1433145at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007296">
        <property type="entry name" value="DUF403"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04168">
        <property type="entry name" value="Alpha-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-E" evidence="1">
        <location>
            <begin position="1"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="316" mass="35762" checksum="AE88F5226406D5AB" modified="2007-12-04" version="1">MLSRTADNLYWLSRYVERADCLARILDVAQRLSHTPVTYGGSTNEWSSAVLTAGCTDGFIARHGPLENATEENVVSFLAFDPANPSSIRNSFEVARTNARSVRTALTSEMWDVINSAWIELRAFPDKAMTREELARFLAFVKETSLRFDGATFRTMLRNDAYWFSRVGAHVERADNTARILDVKYHVLLPEKEHVGGPLDYFQWASILRSVSALTAFHWVYRDSVKPWLVADLLILNRQMPRSLAACYDNLSRSLDDIAGAYGRQGPAQRLARATLAKLSNHSIEDIFQAGLHEFISDFIVDNYKLGNEITEQYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I566</accession>
    <name>A8I566_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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    <dbReference type="EnsemblBacteria" id="BAF88335">
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        <property type="gene ID" value="AZC_2337"/>
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    <dbReference type="KEGG" id="azc:AZC_2337"/>
    <dbReference type="eggNOG" id="COG1250">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_0_0_5"/>
    <dbReference type="OMA" id="DGLALRW"/>
    <dbReference type="OrthoDB" id="862072at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901575">
        <property type="term" value="P:organic substance catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="3">
        <location>
            <begin position="190"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="307"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="332" mass="35297" checksum="795D05B84FD37E7A" modified="2007-12-04" version="1">MDTGRNGPVAVVGGGSMGVGWAIVFARSGREVRVHDAAPAVRSAVLGAVAERLAALAAHDLLSEAPGVVMARITVAETVGAAIAGAVHVQENVPERLDLKTQVFRAMDAVAAPEAVLASSTSSLPASEFAAALPGRARCLVAHPANPPHLLPIVEIVPAPFTDPEAVERTRALMAQAGQVPVVLQREVNGFIYNRLQGAVLREAYWMLEQGIADVASIDRVMTSGLGLRWSIIGPFETADLNYQGGLEEHARRMGERYRQMGAERGQPDGWDETLVARAAAERRALLPLEDWGARVAWRDERLMKARAAERESPPYTASGENTAAGGLREGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="107" xmlns="http://uniprot.org/uniprot">
    <accession>A8I669</accession>
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        <submittedName>
            <fullName evidence="12">Molybdenum import ATP-binding protein</fullName>
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        <name evidence="12" type="ordered locus">AZC_2370</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170896.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2370"/>
    <dbReference type="EnsemblBacteria" id="BAF88368">
        <property type="protein sequence ID" value="BAF88368"/>
        <property type="gene ID" value="AZC_2370"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2370"/>
    <dbReference type="eggNOG" id="COG4148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_5"/>
    <dbReference type="OMA" id="QWLYAQI"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015412">
        <property type="term" value="F:ABC-type molybdate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011868">
        <property type="entry name" value="ModC_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02142">
        <property type="entry name" value="modC_ABC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Mop" evidence="11">
        <location>
            <begin position="293"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="391" mass="42147" checksum="105BA809863A92F7" modified="2007-12-04" version="1">MIEIDVALTRSSSFRLAARFVAPEKGITSLFGRSGAGKSTIIHMVAGTVRPDSGSIRIGDTVFFDAARGIDLAMERRRVGYVFQDARLFPHMRVETNLRYGERRAKGEKRIGFDAVVGMLGIGHLLGRRPHTLSGGERQRVAIGRALLAQPRLLLMDEPLAALDEQRKAEILPYLEVLRDELKLPILYVSHAIEEVLRLSDMVVAMADGGVVAAGSVADVMSQPALLPVVGRFDLGTIVDCTVAAHDTHYALSSLAFPDGELRVPLVDLPLGAPARARIRSRDVALSLSRPMDVSVTNRIAGKVSDIRREEGPYADVGVDLGHVTLRALVTVESVNRLALEPGMPVWVMIKAVAVDSRSPLFAAPADGPFSPPGTPALRLVEPDNPSQANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8I674</accession>
    <name>A8I674_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2023 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2372</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
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                <person name="Backer P.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170951.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2425"/>
    <dbReference type="EnsemblBacteria" id="BAF88423">
        <property type="protein sequence ID" value="BAF88423"/>
        <property type="gene ID" value="AZC_2425"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2425"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_5"/>
    <dbReference type="OMA" id="GQDFSIM"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="428"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="861"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="911"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="957"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1015"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1045" mass="112115" checksum="B626A9CDCE7B4FC7" modified="2007-12-04" version="1">MSISTPFIRRPIATTLLMVALVLVGVVAYPLLPVAPLPQVDFPTIQVSASLPGASPETMASSVATPLERQFAQIAGVTQMTSSSALGVASITIQFDLNRNIDAAAQDVQAAITAASGQLPDNLPSPPTFRKVNPADSPILILSVQSDLYPITKVDDIADTILAQQISQIPGIAQVAITGEQKPAVRVQVDPSKLAALGMSLEDVRTVLANATVDQPKGSFDGPSQSFTIYADDQLLASQPWNDVVIAYKSGAPVRIRDIGRAVDGPENARLASWQNGRRGIQLIVFKQPGANVIDAVDRVRAMIPRLEASLPPGIDVRIITDRTQTIRASVDDVQFTMMLTIGLVVAVIFAFLRSVWATIIPSITVPLALIGTFAVMYLLGYSLDNLSLMGLTIAVGFVVDDAIVMLENIYRHIEEGMAPFEAAIKGAAEIGFTIISISVSLIAVFIPILLMGGIVGRLLREFAMTVTITILVSVVVSLTLTPMMCSRFLKNEHGVKHGRAYMAAEAFFDGMLALYDRGLKWVLRHQTITLLGLLATVIATGAIYVAIPKGFFPQQDTGFIGGFAEAAQDISFAAMSEKQQQLMAIVAKDPAVSSVSVSVGATGGSQTVNTGRMWINLKPQDERDASATQVINRLRPQTAQVPGIQLYLQAAQDINVGGRASRTQYQYTLQDSNLEELNSWAPRMLAKLKTLPQLQDVATDQQASAPIVSLTIDRDTAARFGIQPQVIDNTLYDAFGQRQVAQYFTQLSQYHVVLEVEPGLQQDSLALEKIYVKSPITGDMIPLSTFVKVDTSKTSYLSISHQGQFPAVTLSFNLAPGAALGDAVTAIQQAEREMGKPVTLITNFQGTAQAFQDSLRTQPYLIAAAVIAVYIILGVLYESFIHPLTILSTLPSAGLGALLTLYLTGQDLSVIGLIGILLLIGIVKKNAIMMIDFALQKEREEGMAPERSIYEACLTRFRPIMMTTMAALLGGVPLMLGTGTGSELRQPLGYAIVGGLAVSQILTLYTTPVVYLAMGRVSRAIDRLRGKGGAATPHPDTHVPTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7E6</accession>
    <name>A8I7E6_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2113</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170640.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2113"/>
    <dbReference type="EnsemblBacteria" id="BAF88111">
        <property type="protein sequence ID" value="BAF88111"/>
        <property type="gene ID" value="AZC_2113"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2113"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_5"/>
    <dbReference type="OMA" id="ASHMLSE"/>
    <dbReference type="OrthoDB" id="1475841at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="233" mass="25155" checksum="E2886328306F45D0" modified="2007-12-04" version="1">MLEVRGLRAGYGAVEVLRGIDLQVKAGEIIAVLGSNGVGKTTLNKVLSGVLPLSAGEVTFEGRRLNGLSPADIVEAGLIHVPEGRKIFPNMSVRENLELGSYRRARPRRAANLERVFTTFPRLRERMTQAAGTLSGGEQQMVAIGRGMMAEPKLLILDEPSLGLSPLLVEEMFALIQRLNAGGLPIMLVEQNVVQSLEMASRAYIIENGLVTLEGAAADIRSDPELKRAYLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7M0</accession>
    <name>A8I7M0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Lysozyme</fullName>
            <ecNumber evidence="2 7">3.2.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2137</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="99" mass="11199" checksum="AEF64EDBE560AC29" modified="2007-12-04" version="1">MSMDRLIREEARLIILKALGDQLDETLNSSLLTEELRTFGIKRERAWVHGELAYLAQMGALALMEAGSVKVARLTDLGRRHLDRDVAIEGVKRPSRREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8G6</accession>
    <name>A8I8G6_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2660"/>
    <dbReference type="EnsemblBacteria" id="BAF88658">
        <property type="protein sequence ID" value="BAF88658"/>
        <property type="gene ID" value="AZC_2660"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2660"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_1_0_5"/>
    <dbReference type="OMA" id="WFPIGLS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="112"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="337" mass="36264" checksum="0051CABF1666C837" modified="2007-12-04" version="1">MIRLSGDTSMPGPLRVAKALRRTALQAVPTVLIIVILNFFLLRLAPGDAAEVMAGEAGSATAETLAALRNRFGLDLPVLQQLADYLWTLAHFSLGDSPRYNMPVAALIGQRLPNTLALMALALGLALVIGIALGALMASFVGRLPDRVLSVLALLFYSIPSFWIGLMLIVLFSVKLGWLPSGGAESIGAGYTGWEAFVDRLRFMVLPGLSLALFYVAIYARLTRGDMLEVRAQDYVRTAQAKGLPPFAVTTRHVLRNALLPVTTMAGIHLGGLMGGAVVVETVYSWPGLGRLAYEAVMGRDFNVLLGILLLSSLLVVAVNALIDLFQAWLDPRIEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8I4</accession>
    <name>A8I8I4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-dependent metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2666</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M10B family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2666"/>
    <dbReference type="EnsemblBacteria" id="BAF88664">
        <property type="protein sequence ID" value="BAF88664"/>
        <property type="gene ID" value="AZC_2666"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2666"/>
    <dbReference type="eggNOG" id="COG2931">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_389170_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04277">
        <property type="entry name" value="ZnMc_serralysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025193">
        <property type="entry name" value="DUF4114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018511">
        <property type="entry name" value="Hemolysin-typ_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006026">
        <property type="entry name" value="Peptidase_Metallo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034033">
        <property type="entry name" value="Serralysin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13448">
        <property type="entry name" value="DUF4114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00235">
        <property type="entry name" value="ZnMc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00330">
        <property type="entry name" value="HEMOLYSIN_CALCIUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="ZnMc" evidence="3">
        <location>
            <begin position="49"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="709" mass="74215" checksum="532439FF3CE6EE38" modified="2007-12-04" version="1">MHAICRWDVAMADTQENFTSTIVDQPKGGLYSGSISTVGLDPNVKSELMDYRWTTSFNGSQPATVMTYAFPTSAADYSSIAGGYPDTQELAQFAPLTQTQMDAVRTALGLVASYTNLVFREVTSGLASEATLRFAQFTDTGSESRFPANSGPYASSDSRVAGDTWLGGNGQAPAAYFGTDALNTIMHEMGHAFGLKHGHDGSFNGALAPQFNDNEFSVMSYASYFGANTAGSTEAIAGSSPQSYMMFDIAALQELYGANFSKVGTTDVYKWDPVTGQETINGVPAPNTGASSTGKIFSTVWTAGATVTYDLSAFNEDQVDDLRPGQWLTFSKAQIADLNNEAVAGTAQYQAQGNIYNALLYHGDARSLVSNIITGNGSDKITGNDGNNVISAGAGNDWISGGNGNDIISGGAGADTIIFGSGRNILRDKLADLQGDTVYGFGKTGTLDILDARYDPAAVHSTKTADGAMLTIGSVSFELKGDYAGGDFMSPVRKVGGTTHMDISFVNYTPSLSEGSPVAKGAVNGIADEDFLMGDGDASFTMHMESAGSAYANTLGYYFVGDDGRISNVHLAYTNTLASGNAQKAIALGTPGPDQHIGFFLVQNGHNVFGDLPDDLMFVSADGSGAANVDSGAAPILVSASRGVLTGATVFHSYDELNPGHDIHVLSGTETGGDVLEIGFEDLASAIADNDFQDVVISIHATYQDVMFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I913</accession>
    <name>A8I913_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_2731</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171255.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2731"/>
    <dbReference type="EnsemblBacteria" id="BAF88729">
        <property type="protein sequence ID" value="BAF88729"/>
        <property type="gene ID" value="AZC_2731"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2731"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_3_5"/>
    <dbReference type="OMA" id="LLHGHFD"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="303" mass="32412" checksum="E504D883B1FC25A6" modified="2007-12-04" version="1">MNLRQLEIFRAVMRCQTTMGAATALSMSQPAVSNALKQMESQIGFLLFDRINNRLFPTEAARMIYEDSEPLFAMHAALETRVRDLRDDKVARLRILSTPPLGHGVIAQTLVRFAAANPKVRVGFDVRHLDEVIEGVETGAADLGFGLALGDTPSLKVQALHAGAMVCVCREDHPLAREEVVTPDLLRGRSFVGLEGETRMGQSVRTAFETSGVPYEASVMVRYCGTACVLAAAGLGAAVVDAFSPASSGQAGLVVRPFAPRVPCVASAFWSGLRRPPVAAGRFLDALRVTLSVTVPHLVGQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8I986</accession>
    <name>A8I986_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_2757</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88802.1"/>
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        <property type="gene ID" value="AZC_2804"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0016810">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
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        <property type="entry name" value="Metal_Hydrolase"/>
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        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF51338"/>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="264"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="398" mass="41811" checksum="E3B1BE9A25D4EC5E" modified="2007-12-04" version="1">MAHDAPSGPTGPTKLVIRNIGLLLSGDLEKPILDADTIVAENGRITAIGRLKDVDVEGATTTVDANGAAVTPGLIDSHVHPVAGDWTPRQQQLNWIDSFLHGGVTTMISAGEVHYPGRPRDVVGLKALAITAQRTFTAFRPGGVKIHAGAPVIEHEMVEEDFKELAAAGVKLLGEVGLGGVKDGPTARKMVGWARKYGIQSTIHTGGPSIPGSGLIDKDVVLEADTDVVGHINGGHTALPDSQIRCICEGCKRGLELVHNGNERSALYTLRIAKEMGDLHRVILGTDAPAGSGVQPLGILRMVSLLSSLGDLPAEQAFCLATGNTARMRALDTGLIEVGRAADFVIMDTAQHSAGKNLLESVQLGDLPGIGMTIIDGIVRTERSRNTPPATRVPFLVK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9W7</accession>
    <name>Y2841_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0173 metal-dependent hydrolase AZC_2841</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_2841</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0173 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171365.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I9W7"/>
    <dbReference type="SMR" id="A8I9W7"/>
    <dbReference type="STRING" id="438753.AZC_2841"/>
    <dbReference type="EnsemblBacteria" id="BAF88839">
        <property type="protein sequence ID" value="BAF88839"/>
        <property type="gene ID" value="AZC_2841"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2841"/>
    <dbReference type="eggNOG" id="COG2220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_070010_4_0_5"/>
    <dbReference type="OMA" id="WHGHSTW"/>
    <dbReference type="OrthoDB" id="767622at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00457">
        <property type="entry name" value="UPF0173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022877">
        <property type="entry name" value="UPF0173"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000367161" description="UPF0173 metal-dependent hydrolase AZC_2841">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00457"/>
        </source>
    </evidence>
    <sequence length="236" mass="24693" checksum="86C74E87EFC40928" modified="2007-12-04" version="1">MKITWLGHAAFRLDFAGTAVLIDPFLTHNPVFKGDVAEVSKGVSHILLTHGHSDHIGDTAGIVKAAEAEGRKVIVVANPEVCGFLSGQGLSAFEPMNTGGTVKLDGFSVTMVRADHSSGGDGSNPTYLGNPNGLIVKAAGEPTLWHLGDTDLFSDMALISEIHQPKVAIVPIGDRFTMGPETAALAVRRFISAETVVPCHYGTFPLLVPDASGFVAALQGHSAKVVVPNSGESFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA79</accession>
    <name>A8IA79_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Extracellular solute-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2475"/>
    <dbReference type="EnsemblBacteria" id="BAF88473">
        <property type="protein sequence ID" value="BAF88473"/>
        <property type="gene ID" value="AZC_2475"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2475"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_8_0_5"/>
    <dbReference type="OMA" id="NQVQIDV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="374" mass="40779" checksum="4D819C5F4A4C0980" modified="2007-12-04" version="1">MSQVLITNFRGEPMTDVSGTGPSRRTLLKSAAAGAAAVMMPAVWSPSRAAGKRIVVRDDGGIYTKAYGAVFYKPFTEKTGIEVVGVQAAAEPTAQIKSMVETKNYTWDMAKISKPAILILTDGGTPYLEKHGLESDPVIASIPAQYMSPYGVGTNVYTTVLAYRTDAFQGKKAPKSWADFWNVKDFPGRRAMRKHPFDTVEEALMATGVPTNLVYPCNVDKAFAALDQIKPNIAVWWTSGALVEQVLTSGEVDMIPTWVSRAQAAQAKGAPVEIIWDQGIWGGDHWSILAGTPNADACREFIKFASDPERMAKLTEFFPAGVTQPKAFDYIKPDIAKNCPTFPANIQSGLQIDAAYWLKNQAAVIERFNSWVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAM5</accession>
    <name>A8IAM5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88524.1"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="72" mass="7542" checksum="BE5B0B1DD624E241" modified="2007-12-04" version="1">MFVNADALFNVLVLFNVVVALAALAFVYVVLCLLGRVLPAPEGGRGRMSRMFYVAVGFLALLGAVSAVALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAN9</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF88530">
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        <property type="gene ID" value="AZC_2532"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG0099">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="InterPro"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_S13_S18"/>
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    </dbReference>
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        <property type="entry name" value="Ribosomal_S13_bac-type"/>
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    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
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        <location>
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        <location>
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            <end position="157"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
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    </evidence>
    <sequence length="157" mass="17486" checksum="275BFAF22BD3ECC2" modified="2007-12-04" version="1">MRRDSHGLLLSPQGPASTGRGAFRRPAGVAEMERAVARIAGVNIPTNKRVVIALQYIHGIGPKKAEEIVEKVGIAAERRVNQLTDAEVLQIRETIDRDYIVEGDLRREVAMNIKRLMDLGCYRGLRHRRGLPVRGQRTHTNARTRKGPAKPIAGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="9">Protein translocase subunit SecY</fullName>
        </recommendedName>
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        <name evidence="11" type="ordered locus">AZC_2534</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171060.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2534"/>
    <dbReference type="EnsemblBacteria" id="BAF88532">
        <property type="protein sequence ID" value="BAF88532"/>
        <property type="gene ID" value="AZC_2534"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2534"/>
    <dbReference type="eggNOG" id="COG0201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030313_0_2_5"/>
    <dbReference type="OMA" id="FAMWLGE"/>
    <dbReference type="OrthoDB" id="1567535at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="444" mass="48465" checksum="4C5F3A3DECD582BC" modified="2007-12-04" version="1">MVSAAEQLAANLNFGSLGKAEELKKRIWFTLGALIVFRLGTYIPLPGINPDALQDVFRGAQQGIIGLFNMFSGGAVERMAIFALNIMPYISASIIVQLLTTVSPTLEALKKEGEAGRKKINQYTRYLTVVLAVFQAYGIAVGLERSTGVVMDPGWFFRISTVITLTGGTMFMMWLGEQITSRGIGNGTSLIIFGGIVAELPGAFVRTLELGRQGAISTPIILGVLVMVVCLIAFIVFMERAQRRLLIQYPKRQVGNRLYEGQSSHLPLKLNTSGVIPPIFASSLLLIPTTIASFLQGAGPEWLNQVTALLGHGRPLYMLLYVLLIVFFCFFYTAIVFNPVETADNLKKHGGFIPGIRPGERTAEYIDYVLTRITVVGAAYIAAVCLFPEVLISYAAVPFYFGGTSLLIVVSVTMDTVSQIQGHLLAHQYEGLVKKSKLRGGKRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAQ5</accession>
    <name>RL24_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplX</name>
        <name type="ordered locus">AZC_2543</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAQ5"/>
    <dbReference type="SMR" id="A8IAQ5"/>
    <dbReference type="STRING" id="438753.AZC_2543"/>
    <dbReference type="EnsemblBacteria" id="BAF88541">
        <property type="protein sequence ID" value="BAF88541"/>
        <property type="gene ID" value="AZC_2543"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2543"/>
    <dbReference type="eggNOG" id="COG0198">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093315_2_2_5"/>
    <dbReference type="OMA" id="HVKPTQE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000086468" description="50S ribosomal protein L24">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <sequence length="106" mass="11518" checksum="E1A675C7B278E4BA" modified="2007-12-04" version="1">MMAAKIKKGDKVVVLAGRDKGRTGEVLQVLPKEERALVRGVNVVKRHQRQTAQSEGGIISKEAPIHLSNIAVADPKDGKPTRVGFEVLDDGRKVRVAKRSGERIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB15</accession>
    <name>A8IB15_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    <sequence length="303" mass="32447" checksum="D71A0AF28B1EB669" modified="2007-12-04" version="1">MTPETSAAPVCPGPAPDPHGPTRYAVPPGAVDCHAHVIGVPPAYPFVPQRSYTPPEATAEQYLAMLDGTGMTYGVLVQVSVHGVDNRLMLDTLRANRQRLRGIAVIPLGLADRELAAMKEAGVVGLRLNVLYGGGIGFDALGSYAALAREMDWHLQFLVDAADLMPIAPQLGQLPVPYVIDHWGHFPVSRGLEDPGFQTMLALLRDGGWVKLSGAYRNSVSGPPYADTIPFARRIHEAAPDRCVWGSDWPNVANWGPMMNIGELLDLMADWVPDPVARDRVFTANAQRLYGFPPGAGVGGGAA</sequence>
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                <person name="Lee KB."/>
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                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <begin position="1"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
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            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
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            <dbReference type="ChEBI" id="CHEBI:90726"/>
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    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
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        <property type="match status" value="2"/>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="774" mass="82735" checksum="08C8DEBB0EC271D3" modified="2007-12-04" version="1">MSEIRKAAVIGAGVMGAGIAAHIANAGVEVLLLDIVPEGATNRSAIAEKAVERLLKAEPAAFMSKRSAKLVKAGNIEDDLPALAECDWIVEAVVERLDVKQALYRKIDAVRKPGTAVSSNTSTIPLAALTEGLSDGFRRDFLITHFFNPPRYMRLLEIVSGPETDPATVARVSAFADVKLGKTVVTCKDTPGFIANRLGTYWMQLAVGEAFALGLTVEEADSVMGRPFGIPKTGVFGLLDLVGLDLMPHVQGSLERALPKDDPFQKTVRDIPLIRTMIETGLIGRKGKGGFYRLNREGGGKVKEAIDLASGSYRREEKARLPEVEAAAKNVGALLGATTPAGRYAVSVMARTLAYAAWLVPAAADDVVAIDDAMRLGYNWKWGPFELIDRIGAPALIAALDGMGEPVPEFLTLARDKTFYRVENGKRQYLGRDGIYRDIVRPEGVLLLSDIKLTAQPVLKNSSAAVWDLGDGVLCFEFTSKSNSLDEGIITLLGKASKLVKDKHKALVIYNEGSNFSVGANLGLALFACNIAAFGEVEKLVAAGQQAYQALKYATFPVVSAPAGMALGGGCEILLHSDAVQAHAESYIGLVECGVGVLPGWGGCKEMLTRWQTDPALPKGPMPAPSKVFEMVSTATVSKSAAEAKEYKFLRESDGITMNRDRLLADAKAKALALAENYVPPKPVDLTLPGPSGRVALEMAAESFHKRGIATKHDLVVASALAEVLTGGPADHIQPVTEAQVLELERAGFMKLIRTNATLARIESVLETGRPLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEE9</accession>
    <name>A8IEE9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3482</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3482"/>
    <dbReference type="EnsemblBacteria" id="BAF89480">
        <property type="protein sequence ID" value="BAF89480"/>
        <property type="gene ID" value="AZC_3482"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3482"/>
    <dbReference type="eggNOG" id="COG4944">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097826_0_0_5"/>
    <dbReference type="OMA" id="ATWYTIA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009495">
        <property type="entry name" value="NrsF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06532">
        <property type="entry name" value="NrsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="202" mass="20923" checksum="0E5B2C5465E85B45" modified="2007-12-04" version="1">MAEDAPVRVRLSTVLALAIAAGVVCAGLILLVTIGIRPDLGAAVETVRVQFKLGFTLLMAAAGCAVLLVAGLPGRSAGRRLVVLGLPLALLVLGVVLELTVVPRGRWAASLEGQHAAFCVFFIPVLALVPFAAFFWALRDGAPENPGLAGASAGLAAGAIGAAVYAWHCPDDSPLFVATWYVLAMLLVTVVGYGLGRRTLRW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEU9</accession>
    <name>GLSA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glutaminase</fullName>
            <ecNumber evidence="1">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glsA</name>
        <name type="ordered locus">AZC_3538</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172061.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IEU9"/>
    <dbReference type="SMR" id="A8IEU9"/>
    <dbReference type="STRING" id="438753.AZC_3538"/>
    <dbReference type="EnsemblBacteria" id="BAF89536">
        <property type="protein sequence ID" value="BAF89536"/>
        <property type="gene ID" value="AZC_3538"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3538"/>
    <dbReference type="eggNOG" id="COG2066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027932_1_1_5"/>
    <dbReference type="OMA" id="RPRNPFI"/>
    <dbReference type="OrthoDB" id="1288854at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="PTHR12544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000336024" description="Glutaminase">
        <location>
            <begin position="1"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00313"/>
        </source>
    </evidence>
    <sequence length="309" mass="32659" checksum="944736C746EB0E78" modified="2007-12-04" version="1">MPKLNDVVAEIAADLAKATERGAVATYIPMLAEVPINQFGMAVVTADGETILAGDADTVFSIQSISKVFTLTLALGQIGDALWTRVGKEPSGNAFNSIVQLEYEHGIPRNPFINAGAIVVADAMLSGHQPREALGAILRFVRFVAADESITIDEAVARSEKETGFRNTALANYMRSFGVLRHPVDHALGVYFHQCAIAMSCRHLARAGRYLAFSGRLTPEGPSVVASERARRIAALMLTCGHYDGSGDFAFRVGLPGKSGVGGGILAIAPGKASIAVWSPGLDPHGNSLLGSIALERLAKAMRWSVFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF79</accession>
    <name>A8IF79_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Head-to-tail joining protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Virion</location>
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        <property type="protein sequence ID" value="BAF89586.1"/>
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    <dbReference type="STRING" id="438753.AZC_3588"/>
    <dbReference type="EnsemblBacteria" id="BAF89586">
        <property type="protein sequence ID" value="BAF89586"/>
        <property type="gene ID" value="AZC_3588"/>
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        <property type="entry name" value="Head-tail_con"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0946">Virion</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004328"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022844"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <dbReference type="EMBL" id="BAF89586.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="511" mass="56149" checksum="C1A22CF83785E434" modified="2007-12-04" version="1">MVKPATTAAGRYTQLATIRSPYLERARDCATLTIPSLMPRAGHGAANDLPTPFQGMGARGVNNLGSKLLLALMPPNQPFFRLMLDDFALQELTGQDGMRTEVEKALGQIERAVQTEVETGAIRVSAFEALKQLLVAGNVLLYVQPTGGVKVYRLDRYVVKRDPSGNVLEIVIHERVSPLALPEELQRKLGEQRKGVQDTIDLYTWIRRESGKFVVHQEVKGEKVPGTDGEWPTDKAPFIALRWAKIDGEDYGRGHVEEYIGDLRSLEALTRAIVEGAAAAAKVLFLVNPNGVTNERTISEAPNMAVRSGNKEDVNVLQVEKFNDFRVALETVGRLEIRLSQAFLLTSSIQRDAERVTAEEIRVMAGELEDALGGVYSILAQEFQLPLVRRLIFQMEQDERLPSLPPDLVKPSIITGMEALGRGHDLNRLMMFAKVVNDLLGPGALPSYADARKLIERAGVALSVDTSDILKSDEQLQAEQMQAQQQALLQSLGAEVLKTGLNQENANDAAA</sequence>
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    <accession>A8IFU3</accession>
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        <name evidence="5" type="ordered locus">AZC_3651</name>
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    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="protein sequence ID" value="BAF89649"/>
        <property type="gene ID" value="AZC_3651"/>
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        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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        <property type="entry name" value="HisKA_2"/>
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        <property type="match status" value="1"/>
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        <location>
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            <end position="122"/>
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    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
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        <source>
            <dbReference type="EMBL" id="BAF89649.1"/>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="681" mass="71925" checksum="726B873876C0F742" modified="2007-12-04" version="1">MGVPMSRFRLGIGYKLGIVSGILVLLSGSVIISRQIASSRIQAATEASDVQDSILQKIEAAGATITRIQANAKDIRLSFSSNEVDGLLGRVSSDVTKGMDLMDEASDLTQAAATRDAYKAIRTRFGDIGKAVTEIAKAQKLELESFDRRTGITVRWDGALDDAKASLLDLNSRLGENAISDLSLLDRKLQQINLASWRFIATEDTKQLPVIEMNAKAGRATLDSVLQTAGTDPNTEGPVKTVRTFFEEYLKYVQDGVDQVMLKRKILEERLTPASREVAQMIQQASSNAASGSKQADAAAESARTDGMFQILVFSCISIVAAIVAWAYSGFGIALPIRRVSAVMNEISGGNLAAEIPYGTRNDEVGDQARALAVFRDGLIEAERLREERAEEERLAALQRKTEMHDLADRFESAVGAVVDMVATAATNLQTAAQTLTSTAEQTTAQATAVAAAANQATVNVQTVAAAIEELSASAREIGSRLSRSSEVADRAVSEVDHTNGQMTELRTSADQIGNIISLIDNIAGQTNLLALNATIESARAGEAGRGFAVVAQEVKGLAGQTAKATADISERISGIQDSTGDVLGAITGIAHTIAEISEGTTAIAAAMEEQNATTAEVSRNIQQAAAGANEVTSNIAGVERAAQASSNAALQVLSSATDLSHQADALRAEVQNFLRSVRAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-03-18" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGX4</accession>
    <name>RECR_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recR</name>
        <name type="ordered locus">AZC_0147</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecR family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168678.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IGX4"/>
    <dbReference type="SMR" id="A8IGX4"/>
    <dbReference type="STRING" id="438753.AZC_0147"/>
    <dbReference type="EnsemblBacteria" id="BAF86145">
        <property type="protein sequence ID" value="BAF86145"/>
        <property type="gene ID" value="AZC_0147"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0147"/>
    <dbReference type="eggNOG" id="COG0353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060739_1_1_5"/>
    <dbReference type="OMA" id="DVMAIEN"/>
    <dbReference type="OrthoDB" id="1661836at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015967">
        <property type="entry name" value="Rcmb_RecR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01300">
        <property type="entry name" value="RECR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0233">DNA recombination</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <keyword id="KW-0863">Zinc-finger</keyword>
    <feature type="chain" id="PRO_0000322863" description="Recombination protein RecR">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Toprim" evidence="1">
        <location>
            <begin position="83"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <sequence length="201" mass="21237" checksum="B2FD7259FFF6E5DD" modified="2007-12-04" version="1">MSRAVAGPEIERLIQLLGRLPGLGPRSARRATLHLIKKRETLMAPLGLALQDVLGKIVECQVCGNVDVRDPCTVCTDIHRDSSVLVVVAEVADLWALERANAINAKYHVLGGVLSPLDGVGPDDLNLTKLVERVGAGGVNEVILALGATVDAQTTAHYVTDLLRETGVKVTRLAHGVPVGGELDHLDEGTLSAAIRARTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHN1</accession>
    <name>A8IHN1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Twin-arginine translocation pathway signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3299</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 7 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171822.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3299"/>
    <dbReference type="EnsemblBacteria" id="BAF89297">
        <property type="protein sequence ID" value="BAF89297"/>
        <property type="gene ID" value="AZC_3299"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3299"/>
    <dbReference type="eggNOG" id="COG1638">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036176_1_3_5"/>
    <dbReference type="OMA" id="HQFPGGT"/>
    <dbReference type="OrthoDB" id="752834at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018389">
        <property type="entry name" value="DctP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038404">
        <property type="entry name" value="TRAP_DctP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33376">
        <property type="entry name" value="PTHR33376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721044" evidence="3">
        <location>
            <begin position="32"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="344" mass="37491" checksum="5B86AC34EB5B95DB" modified="2007-12-04" version="1">MTFSRVISRRHVLAGALAAPAVLSFARLGHAATTLKISHQFPSSSGDEGDFRDRLVRRFAAEVEKRSNGELKFEIYPGSSLMKTNSQFSALRKGALDFSLYPISYAGGEAPECNIGLMPCLVSSYAQGLAWKTKPVGEEFNAYLEGKGVKIITWVWQAGGAASREKPLVSPEDAKGMKIRGGSREMDLMLQAAGAAVLNLPSNELYVAMQTGACDAGITSSTSLISFRLEELSKNLAAGKGKSYWFMLEPLLMSKAIFEKLPKEQQDLILKVGAEMEPFGLKGAQEDDHKVVEVFQKAGAKIHDLDDAVLEKWKVIARDTAWKDYAAKTPLSAKLLKLAEEVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHT1</accession>
    <name>A8IHT1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0235 protein AZC_3318</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3318</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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    <sequence length="431" mass="47580" checksum="FFA7ADA62BD73ED0" modified="2007-12-04" version="1">MNAPASPRILVVAHNHPDLHPGGTEIFAHDLFKAYQRAGCEALFLGATSRLHREARPGTSFQTVGSAKDEVLFWTGHFDRFSMSQIDLYGAVPDLVALLRDFRPDVVHLHHLLLIGAEFPALVRRILPHARIVMTLHDYYPICHHDGLMVRTRGGQRCMGASPDACHACFPEIPTERFLLRQQHLKTHLSYVDAFVSPSRFLKARYVDWGLDPAKIEVIANGRPLTSAAPFRPPHEGRRASFGYFGNINPWKGMRVLLDAARRLIGCGVDFELRVHGAALYQSEAFTAEIDRLFAETDSHVLRLGPYERHEVGHLMAGVDWVVMPSVWWENAPLVIQEAQMHRRPVITSGIGGMAEAVRDGVDGLHVLPGDAADLAGVMRRCAEDAALWRRLSAATVPPPSIDAVAARYLRLAGQIARPLAADAATSTVAA</sequence>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89372.1"/>
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    <dbReference type="STRING" id="438753.AZC_3374"/>
    <dbReference type="EnsemblBacteria" id="BAF89372">
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        <property type="gene ID" value="AZC_3374"/>
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    <dbReference type="eggNOG" id="COG0176">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="entry name" value="PTHR10683"/>
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    <evidence type="ECO:0000313" key="2">
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    <sequence length="249" mass="26467" checksum="1C8C01ED62A1F554" modified="2007-12-04" version="1">MSVTLADLKVKLFTDGAEKAQIVEMAKQPHIAGFTTNPSLLRKAGVTDYEAYARDLVAAVPDRHISFEVFSDELPEIRAQAAVIATWGAHVHVKLPITNTKGESLLPMVRDLVQDGVKVNLTAVFSERQVEEGVAALAGGAPSIISVFAGRLADLGIDYLPAITKAVALSRATPNVEVIWASTREVWNVIEADRLGVHIITAPADVLKKLPALGSRTADELSLDAVKAFRTDALAAGLTLDVTGRAAAE</sequence>
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    <accession>A8IJD5</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>acetoacetate + H(+) = acetone + CO2</text>
            <dbReference type="Rhea" id="RHEA:19729"/>
            <dbReference type="ChEBI" id="CHEBI:13705"/>
            <dbReference type="ChEBI" id="CHEBI:15347"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="EC" id="4.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ADC family.</text>
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    <dbReference type="EC" id="4.1.1.4" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_0288"/>
    <dbReference type="EnsemblBacteria" id="BAF86286">
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        <property type="gene ID" value="AZC_0288"/>
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    <dbReference type="GO" id="GO:0047602">
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="Acetoacetate_decarboxylase"/>
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        <property type="entry name" value="Acetoacetate_decarboxylase_bac"/>
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        <location>
            <position position="116"/>
        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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    </evidence>
    <sequence length="248" mass="28076" checksum="8A2D34826FBAE240" modified="2007-12-04" version="1">MKIEDVRRTAYSMPLTNPAYPPGPYRFFDREFMIITYRTDIEALRRVVPEPLEVYEPLVKYEFIRMPDSTGFGDYTETGQVIPVKYEGVEGGYVHSMYLDDEAPIAGGRELWGFPKKYAHPKMEVEKDVLTGRLHYGKTLCVDASMGYKHKAADKDAVLAALKTPSFLIKIIPHVDATPRICELVRYYLEDIVLKECWTGPAALGLFPHAIADVAKLPVLEVVSALHLRADLTLGMGEVVFDYLKDQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="3 4" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Miwa H."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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    <sequence length="522" mass="56999" checksum="3E060665B92A5BD0" modified="2007-12-04" version="1">MILVLIDAARLARAGYVLAREGVLSLVSPAMVPPLARPGLRLARLIARPDAGTRAARLSAALSRLGPSYVKLGQFLATRPDVVGASVARDLEVLQDRMPAFGQTVAEQTVVDAFERPLSEVYAEFGPPVAAASIAEVHKAVVVERDGTRRTVAVKILRPGIERRFSADVATFRRIAAFAEKISAEARRLRLTTVVDTLGRSVTMEMDLRLEAAAYAELAENVKDDPDVHVPAVDWDRSAREVLTTEWIDGIKLSDRAGLEAAGHDLQNLARIVMQSFLRQAMRDGFFHADMHPGNLFVDAEGRLVVVDCGIMGRLGLKERRFLAEILYGFITRNWRRTAEVHFEAGYVPSHHSVEDFALAIRAIGEPIHSRSADQISMARLLSLLLEVTGLFDMKTRPELLLLQKTMVVVEGVARGLDPQLNMWTTAAPVVEDWIAQNLGPVGRLQQAGSGIGEVGRFVLDAPVLLTRAGRVVSQLDEATRNGLHLSPETLEGIGAAEARRAFWGNAALWVIAIALLLLALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL64</accession>
    <name>A8IL64_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_3994</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172514.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3994"/>
    <dbReference type="EnsemblBacteria" id="BAF89992">
        <property type="protein sequence ID" value="BAF89992"/>
        <property type="gene ID" value="AZC_3994"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3994"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_8_9_5"/>
    <dbReference type="OMA" id="YATLMAM"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="287"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF89992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="377" mass="39960" checksum="029D4EE9FB28CEAB" modified="2007-12-04" version="1">MAVPLARKSLIHEWRRFLPATISVAFSGVLMIVQGALLLGIVGANALYVTQSRADLWVGFPGTPSADLGRPIDSGIAADILMDPRISRLETLLLGNGDWRGARGGGMSVTLVGIDTRRDGLGLARSVTPRERVLLQEEGTILVDESDLDKLATDIGATAEINGHMVRIVGVTDNLRSMGGVNVVTSLSTARLLDPALRGADKATYFLAGVEDPRLTSAVRRRLQSFAGKARFESWTAEDLANRSVRYWLLESGAGIGFVFATLIAMLVGTLITSQTLMAAVAASTTQYATLRALGVPFTDLRRIVLKQAGLVGAAGLVLGLACSLLAALLARLNAIPFELRGSIMLLSALVVFSVALVAGLLALRPLRRADPASLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILG4</accession>
    <name>A8ILG4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172550.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4030"/>
    <dbReference type="EnsemblBacteria" id="BAF90028">
        <property type="protein sequence ID" value="BAF90028"/>
        <property type="gene ID" value="AZC_4030"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4030"/>
    <dbReference type="eggNOG" id="ENOG50334BK">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_152495_1_0_5"/>
    <dbReference type="OMA" id="ECDWPEV"/>
    <dbReference type="OrthoDB" id="1880111at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
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        <location>
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            <end position="102"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="102" mass="11026" checksum="FD4A3607651A5C1E" modified="2007-12-04" version="1">MNNWSRAVLAPVLLAGAVVASGAALAQGLPDSRKMSCAQATGMVRQQGAVVLATSQLVYDRYVVSGAYCPMDQQTNPAWVPTRDNPQCFVGYTCYDPTRDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="3">YceI</fullName>
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    </protein>
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        <name evidence="3" type="primary">yceI</name>
        <name evidence="3" type="ordered locus">AZC_4052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172572.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4052"/>
    <dbReference type="EnsemblBacteria" id="BAF90050">
        <property type="protein sequence ID" value="BAF90050"/>
        <property type="gene ID" value="AZC_4052"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4052"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071003_1_0_5"/>
    <dbReference type="OMA" id="IQFRSTS"/>
    <dbReference type="OrthoDB" id="1767227at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724571" evidence="1">
        <location>
            <begin position="28"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="29"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="190" mass="20255" checksum="5642E8BD835C6F85" modified="2007-12-04" version="1">MSMFRRTAGRAAIAAAVLALAAGAVRAAPYVLDPARSAIRFEIGAEGYPLTRGQFRRFTSNLAVDFDHPARSKVSFKVEAASLDTGLPMLDSYVRSDAFLNTERFPAVSFESTSVEKLDDHRVQVTGTLTLLGVSRPEVFVVDVDQSTGKGALGLTARGHIHRSDFGMTAGLPLISDDVAITVAALADTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMC0</accession>
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        <recommendedName>
            <fullName evidence="8">Peptidoglycan-associated protein</fullName>
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    <gene>
        <name evidence="8" type="primary">pal</name>
        <name evidence="12" type="ordered locus">AZC_0525</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Pal lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169056.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0525"/>
    <dbReference type="EnsemblBacteria" id="BAF86523">
        <property type="protein sequence ID" value="BAF86523"/>
        <property type="gene ID" value="AZC_0525"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0525"/>
    <dbReference type="eggNOG" id="COG2885">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_016890_9_2_5"/>
    <dbReference type="OMA" id="MNQGEET"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0009279">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02204">
        <property type="entry name" value="Pal"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OMP_bac"/>
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    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006690">
        <property type="entry name" value="OMPA-like_CS"/>
    </dbReference>
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    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="OMPADOMAIN"/>
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    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="1"/>
            <end position="23"/>
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    <feature type="chain" id="PRO_5002724596" description="Peptidoglycan-associated protein" evidence="10">
        <location>
            <begin position="24"/>
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        <location>
            <begin position="47"/>
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            <dbReference type="ARBA" id="ARBA00022618"/>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02204"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF86523.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="KFase/CYL"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="BAF86590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="269" mass="29068" checksum="31FF7D67E0B4E886" modified="2007-12-04" version="1">MPNGTSLQGERPLPRFIDISIPLENDVPADPPFQKVQIAYHTHGDTAAQLVGSFPGLTVDQLPDGQGWAVEIATISTHNGTHVDAPWHYHPTMDGGARAITIDEIPLDWCFRPGVKLDFRHLPDGHVVTPDEIDAELARIGHTLAPLDIVVVNTAAGARYGHEDYIHSGCGFGRDATLHLVNKGIRVVGTDGWSWDAPFSHTARRFAETGDASLIWEGHKAGRDAGYCQIEKLHNLEALPATGFTVSCFPVKVKGGSAGWTRAVAILPD</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <location>
            <begin position="52"/>
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    </evidence>
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    </evidence>
    <sequence length="323" mass="34914" checksum="4FDE0D06BD7301AA" modified="2007-12-04" version="1">MMARNVRRGRTPVLDLTAQTTLPLELPRPLAGMVAGPAAALDICAADYDVVRRAVAYVTHHVRDQPEVEAIAAAAGVTPRALTDLFRRWCGLTPKAFLQAVTLDRARQVLAECPNVLDAALELGLSGPGRLHDLFVVHEAMSPGEWKTGGAGLVIRYGLHPSPFGTALAMCTPRGLCGLAFADAGEEEAALADMRRRWPYATYLEDPTATAPLVSRIFNPEAWREEQPLRIVFIGTDFEIRVWETLLRIPMGRATTYSTIAGHVGKPSAARAVGAAVGKNPISFVVPCHRVLGKNGDLTGYHWGLTRKRAILGWEAGRIGTEG</sequence>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3686"/>
    <dbReference type="EnsemblBacteria" id="BAF89684">
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        <property type="gene ID" value="AZC_3686"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3686"/>
    <dbReference type="eggNOG" id="ENOG50330QS">
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721794" evidence="1">
        <location>
            <begin position="26"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="173" mass="18690" checksum="952FACFF1F250E98" modified="2007-12-04" version="1">MPMSLKAKICAILFGMACAVSGAQAQDMKGTTEPMKPANWLFVQVADSVTVSDKTLTLKGVAPQTLMFADRPERMTGDTPTAEFTKFWNAGKDSFERDPPNATLSVTVDGKPVTAVVELTNPVLSGDTLTYTYRTLSDDKPATGTSASLFIDWWYARGGVCYRGPYGGLHCHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8INC6</accession>
    <name>A8INC6_AZOC5</name>
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        <submittedName>
            <fullName evidence="12">Sulfate ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cysW</name>
        <name evidence="12" type="ordered locus">AZC_3734</name>
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    <organism evidence="12 13">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="9">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
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        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
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        </subcellularLocation>
        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="protein sequence ID" value="BAF89732.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF89732">
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        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="CysW_permease"/>
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    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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    <dbReference type="InterPro" id="IPR005667">
        <property type="entry name" value="Sulph_transpt2"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF161098"/>
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    </dbReference>
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        <property type="entry name" value="3a0106s02"/>
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    </dbReference>
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        <property type="entry name" value="permease_CysW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="41"/>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="transmembrane region" description="Helical" evidence="10">
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    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="64"/>
            <end position="274"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF89732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="288" mass="30663" checksum="6D028F4DD6BBBA5F" modified="2007-12-04" version="1">MSDTSTRRRVGDGPLARRLIIGLVLLVTVLVLLVPLASIFTEAFQRGVPAYFAALSQPDTLHAMGLTAFTALVCVPVNVIFGIAAAWTVAKFTFPGRGLLLALIELPFSISPIVAGVAYLFVYGAQGLLGPFLEAYDIKIMFAVPAIILASLFVTAPFVAREIVPLMMAQGREEEEAAVTLGASGWRILRTVTLPNVRFALLYGAALCNARVMGEFGAVSVVSGNIRGRTSTLPLQIELLYQDSQVAGAFAAATVLAGVALVTLVAKLIIERLDAERERLNVKRGVGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8INH2</accession>
    <name>A8INH2_AZOC5</name>
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        <submittedName>
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    </protein>
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        <name evidence="3" type="ordered locus">AZC_3751</name>
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    <organism evidence="3 4">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3751"/>
    <dbReference type="EnsemblBacteria" id="BAF89749">
        <property type="protein sequence ID" value="BAF89749"/>
        <property type="gene ID" value="AZC_3751"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3751"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_1_2_5"/>
    <dbReference type="OMA" id="FGAPMQR"/>
    <dbReference type="OrthoDB" id="1374795at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="46"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="242" mass="27089" checksum="D1B69CDACC03CD92" modified="2007-12-04" version="1">MTGEAAAEDQVLGAPVSGPPARRPARVALEGRHVSVRPFDVDLHAADLFAASHGSAEVEALWDFLSVPPFADLDAFRRSYAEAALKDDPLMFALVDPASGRAVGHATYMRIEPAHRVIEVGNILFTPALQRSRAATEAMYLMARHAFEDLGYRRYEWKCNALNAPSRRAALRLGFTYEGLFRQHMVIKGRNRDTTWFSLLDHEWPRAKAAFEAWLAPGNFDADGRQKSRLEDIRNTLEKETP</sequence>
</entry>
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    <accession>A8INS4</accession>
    <name>A8INS4_AZOC5</name>
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            <fullName evidence="1">RebD2 protein</fullName>
        </submittedName>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169230.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0699"/>
    <dbReference type="EnsemblBacteria" id="BAF86697">
        <property type="protein sequence ID" value="BAF86697"/>
        <property type="gene ID" value="AZC_0699"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0699"/>
    <dbReference type="eggNOG" id="COG1014">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4231">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009166_1_0_5"/>
    <dbReference type="OMA" id="PRVVGKF"/>
    <dbReference type="OrthoDB" id="37279at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="624"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1158" mass="125728" checksum="B96D26D2837BB007" modified="2007-12-04" version="1">MGLKQVSLADKYDLAQERVFVSGTQALVRLALMQKERDRQAGLNTAGYVTGYRGSPLGGLDQQFGQAGKLLTANDIRFQPGLNEDLAATALWGSQQAELRGEGKFDGVFGLWYGKGPGVDRSGDVFRHANNAGTSRHGGVLALMGDDHTCESSTTAHQSEFHFVDVMIPVLNPAGAQEILDYGLYGWALSRFAGTWVGLKAVKDTIESTGIVDGRLDRVRIAPVHDFRMPHGGLNIRLADTPPAQEERLQEYKRDAVLAFLRAQKLNRFVTSGGARPRIGIATVGKSYLDVRLALDELGIDEVRANDLGIRLWKVACPWPLETQALYEFARGLDLIMVVEEKRSLIEVQVREELYGTANQPVCIGKKDEEGRWLFPVKGALDPNDIAIQLGRRLLRYGDIPDIAARVAELEEAQRVLAATSDVTTRIPYFCSGCPHNTSTKVPEGMRGSAGIGCHYMVQWMDRATVGFTQMGGEGANWIGEAPFSKRGHLFQNLGDGTYNHSGYLALRAAVAAKVNITYKILFNDAVAMTGGQRHEGDLTVPVIARQVAAEGVARVVLVTDEPDKYAAGINWPAGLTIHHRDELDHIQRELATVPGVTVLIYDQTCASEKRRRRKRGAFPDPDKRVIINERVCEGCGDCGVKSNCVSVQLLETEWGRKREIDQSSCNKDFSCVNGFCPSFVTVHGAKPRKAAGVAGKMGELASLPEPAHPEIDGTYGIIVTGVGGTGIVTIGAILGMAAHLEDKACGMIDMAGLAQKGGAVYSHVRLAKKPEDIAAIRVPARGADLILGGDLVVAGTKKVLAAVKPGKSLVVVNTHEVLPGDFTRNADYSLPTERLKRTISGAVGAEQTHFIEASRLSTALFGNSLPQNIFMVGYAYQFGGLPLSAEAILKAIELNGEAVEMNKAAFEWGRRAAHDPEAMAALLTAKEAATDARRLSESLDEIIARRVDALTAYQDAAYAARYKALVDKVAAAEATRAPGRSGLTEAVARNFHKLMAYKDEYEVARLFADGAFQRQVDAAFEGKLSYEFHLAPPLFARVDPHTGEPRKMRLGPWMMKGFRLLAKLKGLRGTAFDLFGRTEERRTERALIADYERTVSELLGALTRENHATAVAIASIPEKIRGFGHVKLRHLTAAKAEEAALLSTFRTPPVAPAQAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQ16</accession>
    <name>A8IQ16_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gntR</name>
        <name evidence="3" type="ordered locus">AZC_0730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0730"/>
    <dbReference type="EnsemblBacteria" id="BAF86728">
        <property type="protein sequence ID" value="BAF86728"/>
        <property type="gene ID" value="AZC_0730"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0730"/>
    <dbReference type="eggNOG" id="COG1167">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_0_0_5"/>
    <dbReference type="OMA" id="DVFADHS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="2">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="500" mass="54623" checksum="7274A03F5837CB8A" modified="2007-12-04" version="1">MGGGGRDKHQAELYIGAHAAPEREAPDMLSITLDAGGKVPLVSQIVAAVAEQIAEGVLAPGARLPSVRQLAAECSVSTLTVSNAYNRLVAEGYLEARRASGYYVAMRKAAREPQRRQAQNSVPIDALWLLQRVYEDDPNLLKVGSGWLPESHLFTDGLRHSLSALAKKPASAVSRYGNPHGYEPLRRAIQMLLAQRAIDCEPDNIILTHGASQALDIAARGLLQAGDTAFVDDPGYCNLFPTLRALGVRIIGIPRTPQGPDVEALEALAERYRPRVFFTNTILHNPTGTGCPPAVIYRVLRVAEDFDFHIVEDDIFAGMAPDQMPSIASLDQFRRVLYAGSFSKTISPSLRVGYLVVGRDLVERMLYLKLAGGLTSSEISEQVVHSILVDGHHRLHLARLRDKLAVAQKTVCAGLENAGLSIFHRPNGGMFVWAALPGAPDMEAVAHQAMEEGIMLAPGALFRADQKATPFMRFNVTHADHPRLYRFLERVCERALREKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQH9</accession>
    <name>A8IQH9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169316.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0785"/>
    <dbReference type="EnsemblBacteria" id="BAF86783">
        <property type="protein sequence ID" value="BAF86783"/>
        <property type="gene ID" value="AZC_0785"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0785"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_5"/>
    <dbReference type="OMA" id="HITAIHV"/>
    <dbReference type="OrthoDB" id="1200451at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="12"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="349" mass="37639" checksum="D4F133C7FF41FA43" modified="2007-12-04" version="1">MTEKQAPTGAAITLEACGKTFADGTRALEPVNLAITPGETIVLLGPSGCGKTTTLRIIAGLESPDRGGRVLFDGQDVTELPIEKRNVGMVFQSYALFPNMSVIENVAYGLRVRGVAKAERLARAREVLEMMRIDQLADRRIDQLSGGQRQRVALARALAVRPRVILLDEPLTALDAALREHLRAEIDGLLRRLAITAIYVTHDQAEALALGDRIVVMRHGAIAQIGSPRDIYFRPADEFVASFVGVTNRIEGAVRNGVFESAAGRVLLTGGDRDTATLAFRPETAELCAPAEGALRLRVDQVHFQGARQRVQLSAPDGSRIIIEAAAETELSLGQDVGVRLDPSRIAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQK2</accession>
    <name>A8IQK2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable succinyl-diaminopimelate desuccinylase</fullName>
            <ecNumber evidence="5">3.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_0793</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6-diaminoheptanedioate + succinate</text>
            <dbReference type="Rhea" id="RHEA:22608"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:58087"/>
            <dbReference type="EC" id="3.5.1.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.18" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169324.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0793"/>
    <dbReference type="EnsemblBacteria" id="BAF86791">
        <property type="protein sequence ID" value="BAF86791"/>
        <property type="gene ID" value="AZC_0793"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0793"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_2_3_5"/>
    <dbReference type="OMA" id="GDCAPHA"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009014">
        <property type="term" value="F:succinyl-diaminopimelate desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010182">
        <property type="entry name" value="ArgE/DapE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01910">
        <property type="entry name" value="DapE-ArgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="8">
        <location>
            <begin position="193"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="409" mass="43385" checksum="5CD8D50053E0C089" modified="2007-12-04" version="1">MSSLDPARLRALLAETADAQQAFLAELVKVPSDNPPGDCAPHARRAAELLEGLGFEVERHVVPQDKVTAAGMVSVTNLIVRHRFGDGPVIALNAHGDVVPPGEGWSQDPYGAAVVDGVMYGRGVAVSKSDFATYTFALDALKRSGVPLKGTVELHFTYDEEIGGEVGPGWIISEKLTKPDAVISAGFAYAVVVAHNGCLHLEVEVKGKSAHAALPHTGIDALAATTKVLEAIYAYRDTLKATVSPTKGIGSPQITVGLISGGINTNVVPDRITLRLDRRIIPQEQPEAVEAEVKMLIEKAVASYPGASVDIRRILLARPLVPDAESERIAGILCRNASEVVGESVLTNGVPLYTDARLYAEAGIPVVLYGAGPRTIEEANGHRADEKLRLSDLRLATEVVTRTLAELLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQK5</accession>
    <name>A8IQK5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_0794</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0794"/>
    <dbReference type="EnsemblBacteria" id="BAF86792">
        <property type="protein sequence ID" value="BAF86792"/>
        <property type="gene ID" value="AZC_0794"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0794"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="WIENDSR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="329"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="423"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="378"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="685" mass="73026" checksum="A29FEF943915EADF" modified="2007-12-04" version="1">MATTSLQEGERSGGLLRNMSVVARISVGFGFLILLILSVGLYAYMTLSRLGGDLSAMRNAMDRTASATLLERRLNEVWPRAEAAMLGGKTGDLDTAIQQGSGFIAASGQTAAEGIYARYAAGMRDATTKTTATIQDRSKLVAVVPEIDKAFEALIERKKLVFDADGAALVATLQAKVNAGRLNLTRLMNEASTSIETINPPELAKSADASRKEWAAIAAQFEDLIKSSSDPADKEAYEAGLKPVTAYAAGVNSLLPALLDRARILHDTVNVAHTQLVNLVNEVSDQQAALQRSTVDNALELGSWTKTAILGVSIGAMIVGVLVALLVAISIARPLHRLAAAVQEVAQGNTDVDIPSRHEKSEIGLLARALEVFKGNLIAVKAMEAENAERARREEEERQRLSQQLSANFRESVSSIVTDVIRDVERVGKHSESLLQISDSTKESAREARNAVEATSGGISEVASTSTQFASSIREIAERVDESVRLTLDAVERARQTDTVIGELAVSASRISDITRIIQQIAEQTNLLALNATIEAARAGEAGRGFTVVATEVKSLAQQTASATQQIGAQIGAIEQAANGAADFIRQISDQVEAIKGHVTGISASVEEQSSSTTIVAENAQRTSEHADVARTRLDTVFTEAEATLDAARSSRTAADTLKDQAVRLQGVTSDFVNQIETLWTRKSA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-02-01" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>P33217</accession>
    <accession>A8IPA5</accession>
    <name>FCL_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="1">1.1.1.271</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>Nodulation protein NolK</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">fcl</name>
        <name type="synonym">nolK</name>
        <name type="ordered locus">AZC_3850</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1992" name="Mol. Plant Microbe Interact." volume="5" first="405" last="411">
            <title>Identification of a new inducible nodulation gene in Azorhizobium caulinodans.</title>
            <authorList>
                <person name="Goethals K."/>
                <person name="Mergaert P."/>
                <person name="Gao M."/>
                <person name="Geelen D."/>
                <person name="van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
            <dbReference type="PubMed" id="1472718"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <scope>INDUCTION</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1997" name="FEBS Lett." volume="409" first="312" last="316">
            <title>The nodulation gene nolK of Azorhizobium caulinodans is involved in the formation of GDP-fucose from GDP-mannose.</title>
            <authorList>
                <person name="Mergaert P."/>
                <person name="Van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
            <dbReference type="PubMed" id="9202168"/>
            <dbReference type="DOI" id="10.1016/S0014-5793(97)00461-4"/>
        </citation>
        <scope>PATHWAY</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18885"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57273"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.271"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="induction">
        <text evidence="2">By flavanone naringenin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="sequence caution" evidence="4">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="AAB24744" version="1"/>
        </conflict>
    </comment>
    <comment type="sequence caution" evidence="4">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAF89848" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="1"/>
    <dbReference type="EMBL" id="S51942">
        <property type="protein sequence ID" value="AAB24744.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89848.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P33217"/>
    <dbReference type="SMR" id="P33217"/>
    <dbReference type="STRING" id="438753.AZC_3850"/>
    <dbReference type="EnsemblBacteria" id="BAF89848">
        <property type="protein sequence ID" value="BAF89848"/>
        <property type="gene ID" value="AZC_3850"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3850"/>
    <dbReference type="eggNOG" id="COG0451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007383_18_0_5"/>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0536">Nodulation</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000174359" description="GDP-L-fucose synthase">
        <location>
            <begin position="1"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="1472718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="3">
        <source>
            <dbReference type="PubMed" id="9202168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="312" mass="34301" checksum="BC2FCB01C87C097C" modified="2000-05-30" version="2">MGKGKKLLITGGRGMVGRNLIACAARSGWEIIAPTSVDLDLRNAEAVEQYIRRQLPDVVVHAAGVVGGIHANIADPIHFLADNAAMALNVVMSSFRSEVVTLINLSSSCMYPACIEGPLKECDILRGPFEVTNEGYALAKTVGLKICEYIDKLPNFNYKTLIACNLYGVGDNFDPRRSHLLPAIIEKIHKASQCGSESVSIWGDGTARREFMFAYDFAKIIIKALEVPELIPSSMNVGVGKDLSVLEYYSLVARVIGWSGEFVYDLNRPVGMRSKLMDITHLTALGWVPERSLEGGIRSTYQYYITGNEVYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQT0</accession>
    <name>A8HQT0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitooligosaccharide deacetylase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_1060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169591.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1060"/>
    <dbReference type="EnsemblBacteria" id="BAF87058">
        <property type="protein sequence ID" value="BAF87058"/>
        <property type="gene ID" value="AZC_1060"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1060"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062195_0_0_5"/>
    <dbReference type="OMA" id="GNHAWTH"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0536">Nodulation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723805" description="Chitooligosaccharide deacetylase" evidence="7">
        <location>
            <begin position="24"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="8">
        <location>
            <begin position="81"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF87058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="320" mass="33648" checksum="54815F0566935902" modified="2007-12-04" version="1">MPRLSSSLLLALPLCLAAGAAVAAPACYAPSALKAVPGEEKVQPHTSSGNTLAERLLPPVRPVAGALAGSIRRVNLPAGVKMVALTFDLCEASSEVSGYDGALVDYLRDQNVQATFFAGGKWAVSHPERASQIIADPLFEVGNHTWSHANMTVTTGTTMQRQVDDADMAIAARRAGAQAAGCNVADVPERTTLFRFPYGSCSADSMAYVNETGHLAIQWDVDSGDPAFLGAKFMAEAMLKAIKPGSIVLMHANGRGKHTAEALRILIPALKAKGYQFATVSQLIAAGTPVIAATCYSERPGDTKVYDDAARAGRRILPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HR76</accession>
    <name>A8HR76_AZOC5</name>
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        <recommendedName>
            <fullName evidence="5">Cytochrome c-type biogenesis protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cycL</name>
        <name evidence="6" type="ordered locus">AZC_1135</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Possible subunit of a heme lyase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the CcmH/CycL/Ccl2/NrfF family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169666.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1135"/>
    <dbReference type="EnsemblBacteria" id="BAF87133">
        <property type="protein sequence ID" value="BAF87133"/>
        <property type="gene ID" value="AZC_1135"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1135"/>
    <dbReference type="eggNOG" id="COG3088">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_107187_2_0_5"/>
    <dbReference type="OMA" id="MIAADMR"/>
    <dbReference type="OrthoDB" id="1984854at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005616">
        <property type="entry name" value="CcmH/CycL/Ccl2/NrfF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038297">
        <property type="entry name" value="CcmH/CycL/NrfF/Ccl2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03918">
        <property type="entry name" value="CcmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011019876" description="Cytochrome c-type biogenesis protein" evidence="5">
        <location>
            <begin position="23"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="161" mass="17851" checksum="8936DAB6838823A3" modified="2007-12-04" version="1">MTRVIRLLAALFLTFSVLPALAVQPDEVLPDPAMEARARELSKELRCMVCQNQSIDDSDAQLARDLRILVRERLKAGDSNSQVLDFLVARYGEFVLMRPVFSWRNALLWGTPGLVLVLGACAAFFALRRRPTSASQALTPEEEARVKALLAASEEPGTRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8HR77</accession>
    <name>A8HR77_AZOC5</name>
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        <recommendedName>
            <fullName evidence="5">Periplasmic serine endoprotease DegP-like</fullName>
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    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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            <taxon>Azorhizobium</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1136"/>
    <dbReference type="EnsemblBacteria" id="BAF87134">
        <property type="protein sequence ID" value="BAF87134"/>
        <property type="gene ID" value="AZC_1136"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1136"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_1_0_5"/>
    <dbReference type="OMA" id="GPLFNQR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="321"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="406"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="525" mass="53838" checksum="BDECAA305C19F61E" modified="2007-12-04" version="1">MAGMTRERRMTRSTNSSFLTKRRTALMAGVVGLAVAGVAVGQFGYGSTPALAQATTAAPVTAQSFSFADVVQKVTPAVVSVKIKKDVSAQQMAMGGDDEFGGADVPPQIERFLKRFGFENGQGGPGGMQRMPRGGGAGERRVVGQGSGFIISPDGYVVTNNHVVDGASEVDVTMTDGKEYTAKVIGTDPRTDVALIKIDGKNDLPFVKLADGAPRVGDWVIAVGNPFGLGGTVTAGIVSARGRDIGSGPYDDFVQIDAPINRGNSGGPTFDLNGNVIGMNTAIVSPSGGNVGIAFAIPSETVKTVVDQLRQDGKVARGYIGVQIQPVTDDLASGLGLNAAEGALVAQVQPDTPAAKAGLKSGDVVTKVNGDAVKDARDLSRKIGMMKPGASVALTVVRDGKTQAFNVKLEQLPTDQQMASADGNGPATHDVPRLGLQLAPAKSVQGAGAQGVVVTEVDPNGPAAARGIRSGDVILDVGGKTVSNPSDVREGLAAAKAENRKAVLMRVKGEQGVRFVAITLDKSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRB0</accession>
    <name>A8HRB0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Formate dehydrogenase gamma subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1157</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the formate dehydrogenase gamma subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169688.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1157"/>
    <dbReference type="EnsemblBacteria" id="BAF87155">
        <property type="protein sequence ID" value="BAF87155"/>
        <property type="gene ID" value="AZC_1157"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1157"/>
    <dbReference type="eggNOG" id="COG2864">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091368_1_1_5"/>
    <dbReference type="OMA" id="TIMSMIF"/>
    <dbReference type="OrthoDB" id="1612137at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009326">
        <property type="term" value="C:formate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006471">
        <property type="entry name" value="Formate_DH_gsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01583">
        <property type="entry name" value="formate-DH-gamm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="9">
        <location>
            <begin position="28"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="235" mass="26198" checksum="EF3931D9925B7BE7" modified="2007-12-04" version="1">MSDNPRPAPSDVMPGDSVQPGRPVTVNRYTVGARINHWITAISLILLALSGLSLFTPSLFFLTNLFGGGQLTRAIHPWIGVVLFFSFSILFIRFWRANLPKREDVTWVARSGDVLMGHEERLPELGKYNAGQKVVFWGMSALIIVLIVSGLIVWERYFFTYTSIPTQRVALIVHSLAAVGIICIWIIHVYAAIWVKGTMSAMTSGKVTGGWAWRHHRKWLRELVAGKRAGGTPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRD0</accession>
    <name>A8HRD0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1167</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1167"/>
    <dbReference type="EnsemblBacteria" id="BAF87165">
        <property type="protein sequence ID" value="BAF87165"/>
        <property type="gene ID" value="AZC_1167"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1167"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1438376_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="70"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="188" mass="20416" checksum="203114FA995844B4" modified="2007-12-04" version="1">MEVSILDDRGPSRSSRMHANQRFCPEPGTESVCAETMDLSLATCDLMGMMPTRPHASPFMGGARVIETSPLLIVDDEPEYLDEILEALAFEGVSAISASNGIDAVQTLRRCPDIRLVVTDIRMPDMDGIALMEAARQEFSDRDLQFIVVTGHAAKADIERAKAAGVIDCLTKPLSMDALQRALKALPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRM1</accession>
    <name>A8HRM1_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Putative GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169742.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1211"/>
    <dbReference type="EnsemblBacteria" id="BAF87209">
        <property type="protein sequence ID" value="BAF87209"/>
        <property type="gene ID" value="AZC_1211"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1211"/>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015046_0_0_5"/>
    <dbReference type="OMA" id="HREIEFP"/>
    <dbReference type="OrthoDB" id="370464at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
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        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="5"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="224"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="312"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="661"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="874" mass="94212" checksum="BD2375357B228209" modified="2007-12-04" version="1">MRIRRLSIENFRKFRAPVVLDGFSDGLNLVCEPNESGKSTVLEALRAALFERYNSKSGRIRSFRPHGDDVAPTVTVEFEVAGGRWQMAKRFLQGPSVTLDGPDGRFTAEAAEEKLQALLGFNRAGNSGADDDSRGALGLLWVEQGQSFQLGSPAETARRTLEEALASEVGAVTGGRRAKAVQQQVEKALADFYTATGKPTGRLKQAQDAAAASRERASACAQELMQFDEVLKRLETKRNEQRRLVRDIEDPEADKELKALDADIERARRAADALRMADLTCRSATADREALDKRAEVRAGLRAALLKAETAARAALENLNAHAERLAQARRADQAAAEALDTARMQLRQAEELQDKAQAARRSAADRQQLATAFARLDRANGLAAEIARIEARIAGSRMDEAADARLRKLEAAVIATRATLDAGAASLSVTLQPGAAITLDGAPLESGTQISLTRDARIDIPGVGTLAFRPPAGSDASLARHRAASDDLAAFLAAVGHADPAAAHAAARARTQDETARAALRSRLEAECPADPALGLPAGLDALRGALAGRDRPEPLAPDAPQPPAEIDLRPFRTAEIEATARRQAALDSLQKAEVRGVELQGASDRAEGDRLRLAQELAADLAPLPDADLEARQAAARADEARALVDRETAGRAAKALDVEALHQQRERMVKKRERLQADLPNLAGEVARLEEQARTLGGEGPGQRAEAAREEAEAAEATHARLKDEGDALALLLGVLREAQQDAARRYLRPITRRMEPFVRRLLPNASLAFTEDYKPGLLMRGGREEAAELLSKGTQEQLAVLTRIAFADLLIDKGKPASLVLDDALVFSDDDRFEVMTDILADAARRMQVIILSCRASAYRTVDATRLPLG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRP6</accession>
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        <recommendedName>
            <fullName evidence="1">5-oxoprolinase subunit A</fullName>
            <shortName evidence="1">5-OPase subunit A</shortName>
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        <alternativeName>
            <fullName evidence="1">5-oxoprolinase (ATP-hydrolyzing) subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pxpA</name>
        <name type="ordered locus">AZC_4074</name>
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    <organism>
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-oxo-L-proline + ATP + 2 H2O = ADP + H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10348"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58402"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.5.2.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex composed of PxpA, PxpB and PxpC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LamB/PxpA family.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.9" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172594.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HRP6"/>
    <dbReference type="SMR" id="A8HRP6"/>
    <dbReference type="STRING" id="438753.AZC_4074"/>
    <dbReference type="EnsemblBacteria" id="BAF90072">
        <property type="protein sequence ID" value="BAF90072"/>
        <property type="gene ID" value="AZC_4074"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4074"/>
    <dbReference type="eggNOG" id="COG1540">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069535_0_0_5"/>
    <dbReference type="OMA" id="DRTYKQD"/>
    <dbReference type="OrthoDB" id="918580at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00691">
        <property type="entry name" value="PxpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000083115" description="5-oxoprolinase subunit A">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00691"/>
        </source>
    </evidence>
    <sequence length="253" mass="26414" checksum="DF289EF31545D409" modified="2007-12-04" version="1">MPSVDLNSDLAEGFGIWHLTEDEALMDIVSSANIACGLHAGDPEIMAKAFAYAKSRGVAVGAHPGFPDLWGFGRRRMPFTPGEIERLVAYQVGAAQALATYSGHRITYVKVHGALGNIAEQEPEVAVAVANAVKAVDPSLVVLAGPLGAQAPATRDAGLRLAAEIFADRGYTEQGHLIPRSQPGAMIHDPVAAADRIIAMVQSGAVITAQGTHLPTSIDSICVHGDGPKAVETARYVRERLEAAGIAIAPFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRS3</accession>
    <name>A8HRS3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4087</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172607.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90085">
        <property type="protein sequence ID" value="BAF90085"/>
        <property type="gene ID" value="AZC_4087"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4087"/>
    <dbReference type="HOGENOM" id="CLU_1567492_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="170" mass="17403" checksum="211673D0740DAD84" modified="2007-12-04" version="1">MTSVSSTTSSLVTGLTASTGGSGRLARLQDQLEQAQQALEEAQEANDQEEIAAQQKTIAALQQQIQQLEQQQQQQTQAAQQTQGTSATGRTDATSATSGTSTTSSSSATSSSNATGGSNPYRPVMKLDLAAIAERVRASGEDKTGAADVSGETSAEQAASESLEKSTSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSY3</accession>
    <name>A8HSY3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0434 protein AZC_4232</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0434 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="108" mass="12287" checksum="701CED58AC26C5ED" modified="2007-12-04" version="1">MRKVKDAAAPAKSPWRPWPGWIWCARDAPAPRQTRTRVMTQAQRPGQDVDPKLLEILVCPVTKGPLDYDRARQELISRSARLAYPIRDGIPIMLADEARRLDESEIKG</sequence>
</entry>
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    <accession>A8HT42</accession>
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            <fullName evidence="6">RNA polymerase sigma factor RpoH</fullName>
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        <alternativeName>
            <fullName evidence="6">RNA polymerase sigma-32 factor</fullName>
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    <gene>
        <name evidence="6" type="primary">rpoH</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with the RNA polymerase core enzyme.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF90251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4253"/>
    <dbReference type="EnsemblBacteria" id="BAF90251">
        <property type="protein sequence ID" value="BAF90251"/>
        <property type="gene ID" value="AZC_4253"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4253"/>
    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014793_3_5_5"/>
    <dbReference type="OMA" id="YQRWLAE"/>
    <dbReference type="OrthoDB" id="1565734at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="Sigma70_RpoH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
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        <property type="entry name" value="RNA_pol_sigma70"/>
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        <property type="entry name" value="RNA_pol_sigma70_r4"/>
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        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
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        <property type="entry name" value="RNA_pol_sigma_RpoH_proteobac"/>
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    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
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    <dbReference type="SUPFAM" id="SSF88659">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
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    <keyword evidence="2 6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="77"/>
            <end position="90"/>
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            <begin position="254"/>
            <end position="280"/>
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            <begin position="255"/>
            <end position="274"/>
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    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="53"/>
            <end position="122"/>
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    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
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            <begin position="77"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="300" mass="34130" checksum="8F67EEE5F8D54F22" modified="2007-12-04" version="1">MAGSRQAPIPSAEGGLTRYLEEIRRFPMLEPQEEYMLAKSWREHGDRDAAHKLVTSHLRLVAKIAMGYRGYGLPISEVISEGNVGLMQAVKRFEPEKGFRLATYAMWWIRASIQEYILRSWSLVKMGTTAAQKKLFFNLRKAKSQISALEEGDLRPDQVKQIATKLGVTEQDVVDMNRRLSGDASLNAPLREDGDGGGEWQDWLQDDHQDQETNLVESEELDNRRTALSSALAVLNPRERRIFEARRLSEDPVTLEELAAEFGVSRERVRQIEVRAFEKVQKAVVDKVRTIENVGEPEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT61</accession>
    <name>A8HT61_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">ATP synthase protein subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4259</name>
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    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <location>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="389" mass="42086" checksum="F920A6E551DF4B77" modified="2007-12-04" version="1">MKALTFHGKGDIRCEQVPDPTIQEPTDAIIKVTACAICGSDVHIYDGVIPSMESGDVLGHETMGEVVEVGSGTTTLKVGDRVVVPFTIACGQCFFCQRGYFSGCERSNPNHQMAEKMWGFSPAGLYGYSHMLGGYSGGQAEYLRVPFADSGPIKVPNGLSDEQVLFLSDIFPTGYMAAEFCEIRGGETIAIWGCGPVGQMAIRSAFMLGAERVIAIDTVPERLALAQAGGAETIDFLAEDVYERIREMTGGRGADACIDAVGTEADASSSFDARIDRIKVATFMGTDRPHVLRQAIQCCRNFGIVSIVGVYGGFLDKIPMGSAINRGLTFRMAQTPVQRYLPTLLKRIEDGDFDPSFVITHRASLEEGPDLYAKFRDKQDGCIKVVLKP</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169494.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0963"/>
    <dbReference type="EnsemblBacteria" id="BAF86961">
        <property type="protein sequence ID" value="BAF86961"/>
        <property type="gene ID" value="AZC_0963"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0963"/>
    <dbReference type="eggNOG" id="COG2303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008878_4_0_5"/>
    <dbReference type="OMA" id="MAPYPST"/>
    <dbReference type="OrthoDB" id="365211at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016614">
        <property type="term" value="F:oxidoreductase activity, acting on CH-OH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMC_OxRdtase_N" evidence="1">
        <location>
            <begin position="15"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="GMC_oxred_C" evidence="2">
        <location>
            <begin position="390"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="522" mass="56798" checksum="C6BA4BB17784113D" modified="2007-12-04" version="1">MAQFDRNDDSVVVIVGSGAGGGTLGNELAQKGIKVVILEAGARNEIQDFVNDEWESFAQLAWTDMRVASGSWRVARDFPNLPAWIVKSVGGSTVHWAGASLRFEQHEFKAASAYGGIKGANLLDWPITKAELDPYYAKAEDKMGVTRTNNIPGLPGNNNEKVLEAGARKIGYKDFSTGRMAINSQPRDGRGSCQQIGFCFQGCKSGAKWSTLYTEIPKGEATGNLEVRPNCHVAKIEHDANGKVTAVVYFDETGATQRQKARVVAVAGNSIESPRLLLNSASSLFPNGLANSSGQVGRNYMRHVTGSVYAAFEKPVHMYRGTTMAGIIRDEARHDPGRGFAGGYEMETLSLGLPFMAAFLNPGAWGRSFTSAMENYPRMAGMWLVGEDMPQEKNAITLDKEAKDKFGLPVANVHYDDHSNDVAMRNHGYQQGAALYEAVGAVQTYPTTPYPSTHNLGTNRMSEKPRDGVVNKFGQSHDIKNLFVSDGSQFTTSAACNPTLTIVALAIRQADHMAELMRRRDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUS4</accession>
    <name>A8HUS4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPR domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0977</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169508.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0977"/>
    <dbReference type="EnsemblBacteria" id="BAF86975">
        <property type="protein sequence ID" value="BAF86975"/>
        <property type="gene ID" value="AZC_0977"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0977"/>
    <dbReference type="eggNOG" id="COG0507">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001613_7_2_5"/>
    <dbReference type="OMA" id="ITLHQFA"/>
    <dbReference type="OrthoDB" id="961809at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003840">
        <property type="entry name" value="DNA_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02689">
        <property type="entry name" value="Herpes_Helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Herpes_Helicase" evidence="4">
        <location>
            <begin position="358"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="432" mass="47094" checksum="7C66C828D7825867" modified="2007-12-04" version="1">MSLVPAPEDGAVRALRHIDAGARALLVLGGAGTGKTTFLHELRKTPRGRQVFLAPTGVAALQLGGQTLHSFFGIPPRILQPEEVKPRVQVRRLLKKLDRLVIDEISMVRADLLDTVDRTLRIARESNTPFGGVQVVLVGDFLQLPPVVPYAEQEILEHMGYEGPFAFHAKVLSDHPVARVPFTVVHRQQDDAFIGHLSAIRRGERLNEALTALNEACVRPHRSGVLPVLLTPTNARADAYNQRGLAALPGGERQFEGVLKGEFGLDGDRLPVPERLVLKTGARVMALRNDPARRWVNGSVGTVTGIGPHSALVRLDGGGSVEIEAFTWERMRYVFDEKTGKIESDVVGTYTQLPLVPAWAMTMHKAQGLTLEDVRIDFDNGAFAAGQAYVALSRARSLAGLSLVRPIRPSDIKVDRRVAAFVRDFEASALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV43</accession>
    <name>A8HV43_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="1">AGPR</shortName>
            <ecNumber evidence="1">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="1">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argC</name>
        <name evidence="3" type="ordered locus">AZC_1008</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169539.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1008"/>
    <dbReference type="EnsemblBacteria" id="BAF87006">
        <property type="protein sequence ID" value="BAF87006"/>
        <property type="gene ID" value="AZC_1008"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1008"/>
    <dbReference type="eggNOG" id="COG0002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006384_0_1_5"/>
    <dbReference type="OMA" id="GTHHPTR"/>
    <dbReference type="OrthoDB" id="951261at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
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        <property type="project" value="UniProtKB-SubCell"/>
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    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="2">
        <location>
            <begin position="4"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="324" mass="34008" checksum="F538F2CEE3390027" modified="2007-12-04" version="1">MSIRVGIVGISGFGGGEALRLIASHPSFELVYAAGESSAGSRLVDRFPGVPAKLAELLIQKWDPAALPPLDVLFASLPTGASADALARVPKDVKVVDIGGDHRYVEGWVYGLADIWPTRIEGQTRIANPGCFPAATLIPLAPLLADGLIEPGNIVMDVKTGISGAGRGGDSKFGYAESNENLIPYGLLKHVHMPEIASTIERLSGGSAAGLVFTPHLVPMTRGILATIYCRGEATTDRCLDAARRFYAERPFVRVTDKPPQTKWASGSNLAFVSYAADPERNLVIAMGVVDNLGKGAAGQAVQNANLMCGLPETAGLDGAPVWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV52</accession>
    <name>A8HV52_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">recF</name>
        <name evidence="9" type="ordered locus">AZC_1012</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecF family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169543.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1012"/>
    <dbReference type="EnsemblBacteria" id="BAF87010">
        <property type="protein sequence ID" value="BAF87010"/>
        <property type="gene ID" value="AZC_1012"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1012"/>
    <dbReference type="eggNOG" id="COG1195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040267_2_0_5"/>
    <dbReference type="OMA" id="GESWSYA"/>
    <dbReference type="OrthoDB" id="891841at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="PANTHER" id="PTHR32182:SF0">
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            <dbReference type="ARBA" id="ARBA00008016"/>
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        <source>
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    </evidence>
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        <source>
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        <source>
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            <dbReference type="HAMAP-Rule" id="MF_00365"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF02463"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87010.1"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="378" mass="39983" checksum="B19EDF2929AE5109" modified="2007-12-04" version="1">MTAPRARVRRLTLSRFRSYSAAQIEVADGPVVLTGPNGAGKTNILEAVSLLSPGRGLRRAALDAFAQAGGDGSWAVAAHVEGALGPVDLGTGSDASRPDGSTRRCRIDRESVSSANAFLDHLKVVWLTPEMDGLFTGPPADRRRFLDRLVLAVDASHGTRVNALERALRSRNRVLEDGGDNRMLSAVEHELAELGVAVAAARLETVQRLAGEIAAHADETSPFPHADIALDGALERMLTDAPAVEVEDRYRALLQDNRPRDRAAGRTLEGPHLCDLVVAHGPKGLPAARCSTGEQKSLLIGLALSHARLVTAMQGLAPVVLLDDVVAYLDAERRSGMFAALKALGAQVWMTGADPSAFAALDGAERFTVSPGAVNRSV</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF90309.1"/>
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    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4311"/>
    <dbReference type="EnsemblBacteria" id="BAF90309">
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        <property type="gene ID" value="AZC_4311"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4311"/>
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    <dbReference type="HOGENOM" id="CLU_1444912_0_0_5"/>
    <dbReference type="OMA" id="LITVCDY"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR024467">
        <property type="entry name" value="Xre/MbcA/ParS-like_toxin-bd"/>
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    <dbReference type="Pfam" id="PF09722">
        <property type="entry name" value="DUF2384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2384" evidence="1">
        <location>
            <begin position="137"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="187" mass="19886" checksum="5FEB9B418E45A0B9" modified="2007-12-04" version="1">MAAQRHRAGGEVKDEAKRLRALALHHGCARGADVASYERRCYHSFSGNGGDRTFMPMSHPRMHARPGAEGRPDAGAVVTKAVVRAADALGLTAKRLGEVIGVSEATVSRMRKAGHVLEAGGKPFELAVLFVRLFRGLDAIVGGDAPAARAWMQAENAALGAVPAERIRTVTGLLDVIAYLDARRARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVG7</accession>
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        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
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    <gene>
        <name evidence="4" type="ordered locus">AZC_4313</name>
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    <organism evidence="4 5">
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172833.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4313"/>
    <dbReference type="EnsemblBacteria" id="BAF90311">
        <property type="protein sequence ID" value="BAF90311"/>
        <property type="gene ID" value="AZC_4313"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4313"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_5"/>
    <dbReference type="OMA" id="KMPERDY"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="152"/>
            <end position="156"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="245" mass="25361" checksum="BB21BC96AC53F035" modified="2007-12-04" version="1">MFDLSGKTALVTGATGGLGGAIAKALHAQGATVAISGTRREALDALAGELKDRVHVLPCNLGVAEEVEKLVPDAEAAMGVVDILVNNAGITRDNIFMRLTDEAWEQVLNVNLTSAFRLSRAAVRAMMRRRTGRIISITSIVGVTGNAGQGNYAAAKAGMIGMSKALAQEVASRGVTVNCIAPGFIATPMTDALNDKQREAILKSVPAARLGTPEDIAAACVYLASDEAAYVTGQTLHVNGGMAMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8HW33</accession>
    <name>A8HW33_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4387</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172907.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4387"/>
    <dbReference type="EnsemblBacteria" id="BAF90385">
        <property type="protein sequence ID" value="BAF90385"/>
        <property type="gene ID" value="AZC_4387"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4387"/>
    <dbReference type="eggNOG" id="COG4559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_11_5"/>
    <dbReference type="OMA" id="DMHHQIN"/>
    <dbReference type="OrthoDB" id="1752365at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="262" mass="27441" checksum="893D8748DB346F4E" modified="2007-12-04" version="1">MDPTQAYQAEAASLVRQGRALVRDVSLSLMPGTVTVIVGPNGAGKSSLLKLLAGEVKPSSGRVTLDGADIRTLSPAALARRRAVLPQSSEVAFPFRVEEVVAIGLLGDQPSARARVERVLEQVDLPGFAARTYDSLSGGERQRVQLARALAQLEVMPPDQPGYLLLDEPTASLDLAHQLLVLRHARRHAEQGGAVLAILHDLNLAAMAADRLVVLVQGAIVAEGPPAEIMTDAIIGASFGVAARVNAVPDGPFLLPQTVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWJ6</accession>
    <name>A8HWJ6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4439</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    </comment>
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    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721240" evidence="1">
        <location>
            <begin position="25"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87479.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="109" mass="11336" checksum="64CF5B25AA626F19" modified="2007-12-04" version="1">MRVPLTPIALTTGLLLALTCGANAQSNLTLPPIDPPAVPQTCAAFAALVKSQGAVVVGNSPQTIQRYVKDQAFCAYQQVANPAWIALSDNPQCFVGYTCGDNNDSGSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXK5</accession>
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        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
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    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1512</name>
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    <organism evidence="8 9">
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <topology evidence="1">Peripheral membrane protein</topology>
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    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="match status" value="2"/>
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        <location>
            <begin position="30"/>
            <end position="278"/>
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    <feature type="domain" description="ABC transporter" evidence="8">
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            <end position="587"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="64"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="374"/>
            <end position="381"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF87512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="595" mass="64504" checksum="402723658299090B" modified="2007-12-04" version="1">MRTGPMHGVIDPATLKQAPAEEARGPLLEVRDLTVEFATRRGLVRAVEKVNLTLAKGETLGIVGESGSGKSVTSYTVMRILDRAGRIAEGSITFSGIDVAHADERAMRDLRGREMSMIFQNPRAALNPIRTVGQQIGDVLLQHVQAEPRNVKEKVIDILNQVRIARPEERYHAYPFELSGGMCQRIVIALALACRPQLMIADEPTTGLDVTTQKAVMDLVTELTRARGMSTILITHDLGLAAAYCDTVMVMEKGKVVETAPAEQIFRNPQHAYTRKLMRATPRPGISLRDLLPAEELASSTAAPATPAAEAASSPGEPLLKVENLLKEYPRQGAPSTFLAKLTGKAPEPKDLIFRAVDGISFEVKKGESVGLVGESGCGKSTTSTIVMRLIDPTSGRITFDGQDIGAIPARCFAHHPLRRRIQMVFQDPTESLNPRYTASRAIADPLLRMGGMGGIGGGSALDDKVEELARMVGLPLDLLDRFPHQLSGGQKARVGIARAIALKPDLVILDEPTAALDVSVQAVVLNLLEELKQTLGMSYLFVSHDLHVVRLLCDRVIVMRQGRVVEEGTSQEVLEAPKDAYTRELIAAIPHPPV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYT3</accession>
    <name>HIS2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="1">PRA-PH</shortName>
            <ecNumber evidence="1">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisE</name>
        <name type="ordered locus">AZC_4497</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PRA-PH family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173016.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HYT3"/>
    <dbReference type="SMR" id="A8HYT3"/>
    <dbReference type="STRING" id="438753.AZC_4497"/>
    <dbReference type="EnsemblBacteria" id="BAF90495">
        <property type="protein sequence ID" value="BAF90495"/>
        <property type="gene ID" value="AZC_4497"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4497"/>
    <dbReference type="eggNOG" id="COG0140">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123337_0_0_5"/>
    <dbReference type="OMA" id="FTHEKGE"/>
    <dbReference type="OrthoDB" id="2022633at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000319639" description="Phosphoribosyl-ATP pyrophosphatase">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <sequence length="109" mass="11697" checksum="BD987DF40E78B62A" modified="2007-12-04" version="1">MSEDRVTLADLERIVAARAQADAGASYTRSLLDKGISKCAQKLGEEAVETALAAVGSDKAAVISETADLLYHLAVLLHAKGVELDEVHAELARRTRQSGHEEKASRQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYU3</accession>
    <name>A8HYU3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="9">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisH</fullName>
            <shortName evidence="9">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisH</name>
        <name evidence="12" type="ordered locus">AZC_4500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EC" id="3.5.1.2" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173019.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4500"/>
    <dbReference type="MEROPS" id="C26.965"/>
    <dbReference type="EnsemblBacteria" id="BAF90498">
        <property type="protein sequence ID" value="BAF90498"/>
        <property type="gene ID" value="AZC_4500"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4500"/>
    <dbReference type="eggNOG" id="COG0118">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071837_2_0_5"/>
    <dbReference type="OMA" id="WVYFVHS"/>
    <dbReference type="OrthoDB" id="1726024at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="7 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="11">
        <location>
            <begin position="14"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" evidence="9 10">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF90498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="215" mass="22696" checksum="122AB7C6B429E8C5" modified="2007-12-04" version="1">MTVAIVDYGSGNLHSAAKAIERAALDTGGERIVVTSDPDVVRAADRVVLPGVGAFADCRRGLDAVPGMVAALEEAVHGRGRPFLGICVGLQLLAERGLEHGVTAGLGWIKGEVDRITPSDPDLKIPHMGWNTLQPARAHALLEGIPLGPDGLHAYFVHSYAFKLADPADLLATTDYAGTITAAVARDNVAGTQFHPEKSQKLGLALLANFLKWRP</sequence>
</entry>
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    <accession>A8HZI9</accession>
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        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase and ligase</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4588"/>
    <dbReference type="EnsemblBacteria" id="BAF90586">
        <property type="protein sequence ID" value="BAF90586"/>
        <property type="gene ID" value="AZC_4588"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4588"/>
    <dbReference type="eggNOG" id="COG1022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_45_5_5"/>
    <dbReference type="OMA" id="RGMRKYD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="31"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="656" mass="72933" checksum="68F7975BB4279E0C" modified="2007-12-04" version="1">MRPAMTTAHALTQAYPDVSVLDTFPKLLAHNAAAHGGDVWLREKKFGIWNAFTWAEVEARVRHMALGLTELGVGPGDVVALIGDNRPEWLMGEIAAHAVRGMSLGIYRDALAEEVAYLITYAGVRVIFAEDEEQVDKLLQLGEQIPTVRHIVYSDPRGLRKYDDPRLVALSEIEARGAEHAKREPGRYGELVAAGQGTDVSILCTTSGTTSHPKLAMLTGGALVRHCAAYLKADPRGPQDEYVSVLQMPWIMEQIYAFGQALISRMKVNFVEEPETTMADMREIGPTFVLFAPRVWEQIAADVRARIMDASPLKRAMFDYGMKLGLKALDEGRRSPVADFLLFRALRDRLGFSHLTSAATGGAALGPDTFRFFLALGVPMRQLYGQTELLGAYTLHTADDVDFDTVGKPFEGVDLRIDDPDPNGLGEIVTRHGNAFAGYYLNEEETAKSLDAEGWLRTGDAGYFDKRGHLVVIDRVRDLARTAQGDRFSPQYIENKLKFSPYVAEAVVLGDGRESLAAIICIRFPIVSKWAEKNRISFTTYTDLSSRPEVTELIRAEVEQVNRTLAEKQRLSRFVLLYKELDADDGELTRTRKVRRGVINERYGEIIDAMYRGDRKIDVDTTIAFQDGTKQRIRTVLNVTHLTDAPPAGAGKRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZM5</accession>
    <name>A8HZM5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Smr protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4602</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="438753.AZC_4602"/>
    <dbReference type="EnsemblBacteria" id="BAF90600">
        <property type="protein sequence ID" value="BAF90600"/>
        <property type="gene ID" value="AZC_4602"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4602"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01713">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="100"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50828"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF90600.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="204" mass="22492" checksum="703863D10937363D" modified="2007-12-04" version="1">MTPRRRKRVLREDERALWEHVSRSVAPLRPRPALPAKPETPPPEEPAPPAETEGRAPKGPVLHPRKRPLAPAAPPPPPLTKIEPKVRRKLNRGADVDARLDLHGLTQAAAHRRLHLFIMDAQAAGHSLVLVITGKGDSEGLGLGLGLGWLRGGEAGRGVLRRAVPQWLSDHALRPYVVGFENAARHHGGEGALYVRIRRRRERS</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF87301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1303"/>
    <dbReference type="EnsemblBacteria" id="BAF87301">
        <property type="protein sequence ID" value="BAF87301"/>
        <property type="gene ID" value="AZC_1303"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1303"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
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    </dbReference>
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        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
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        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
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    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
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        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Lactamase_B"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724043" evidence="5">
        <location>
            <begin position="23"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="154"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="708" mass="78252" checksum="C09AB33E1D921422" modified="2007-12-04" version="1">MVKRGMPMVSRRDILKSGPASAAAFAIGGNFLLEGTPARADTPAPPAAGHFHPRGKAPSRHTVAVLKAAREGLPFHDTRDFDEQKRGLIAPMTEMVIAADGGHVAWDMNSFQFLDQQQEFDSIHPSLHRISRLNNNYGLYEVVPGIYQVRGFDLSDISFVRGKTGWIVFDPLVSAETARAAWRLFQAHKGEGLPVSAIIYSHTHGDHWGGVRGIVDEADVRSGKIPIIAPIDFMDFTVSENVYAGNAMNRRLFYQYGLLLKAAPHGYVGQGLGTRVSAGSVGLIAPTRFVREPIEEFEVDGVRMVFQNTPNTEAPREMNTWIPDLKALWMAENVTATLHNIYTLRGAQVRDPLAWSKYISEALYRFGLQAEVMFASHHWPRWGNARIQEILRGQRDLYANMNNQVLHLANQGVTINEIHNVYEVPKSLQARWDCRGYHGSPQHNARGVIQRYLGFWDCNPATLIPLSPSDSAPLYVEMMGGSAKIIARGRALHDEGKYMLAVEIVNKLVQAEPQNTEAKELLADIFEQIGYQQENPGLRNSFLNGAYELRSGISQGEKVSSSSPDVIRAMTTELFLNFLGIRMDSRKAEGLRFTINLVTPDNGEKFIIELDNATLTNIAGFQAEKPDLTLTINRSDLEQTMMGTKTLAAQIADGTAKVTGDVSILAKLAATMIDFDPRFEVMPGTAAKAKEVVAADGFEAVPEKIIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
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    <name>A8I0Z8_AZOC5</name>
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        <name evidence="3" type="ordered locus">AZC_1316</name>
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    <organism evidence="3 4">
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="453" mass="48530" checksum="0A41601DA1B4B250" modified="2007-12-04" version="1">MNLHALLAQRAASGKPVRVGLIGAGKFGSMVLAQAQRIEGMHVVGVADLNVGRARASLARVGWPEERYGATSLADAFKSGKTCVLDDANALAAFDGVECIIEATGHPIAGVRHALAAIDAGKHVVMVNVEADVLCGPLLAERARQKGVVYSMAYGDQPAIICELVDWARSCGFELTSAGKGMNFEPRYRYSTPDTVWGFFGWSEEEVAKGDFNPKMYNSFTDGTKAAIEMAAVANGTGLDCPDDGLAFPPTGLHDLARVFRPVSDGGRLPRSGLVDIAASQEPDGREVFNNIRYGVFVTFKATSEYTKACFKQYGLLTDPSGWYGSMWRPFHMIGLETSISVLSAVLRHEPTGCSKEFRGDAVATAKRDLKPGEMLDGEGGYAVWANAIPASKSLALRGLPIGLAHNVKLKRPVARDQIVSIDDVELEADLDVVALRRQMEDAARPKAARSAA</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <property type="protein sequence ID" value="BAF87944.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1946"/>
    <dbReference type="EnsemblBacteria" id="BAF87944">
        <property type="protein sequence ID" value="BAF87944"/>
        <property type="gene ID" value="AZC_1946"/>
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    <dbReference type="eggNOG" id="COG0251">
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    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
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        <property type="entry name" value="YjgF/YER057c/UK114"/>
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    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
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    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    <sequence length="131" mass="13538" checksum="B39E44F5E613DA6A" modified="2007-12-04" version="1">MSAPEIIEVPVVSEAIRRLGAPTSALVRAGGLLFTCGMPPLDLATGAIVGGPIEVQAECSLDALAFALAHAGSSLDRVVKATVFVTDPALMGPVNRIYAARFTGGFPARTSAAIKPWSQPFDIEIECVAMA</sequence>
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    <accession>A8I355</accession>
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        <name evidence="8" type="ordered locus">AZC_1983</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF87981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="Oligopep_ABC_C"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AAA"/>
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    <keyword evidence="3" id="KW-0813">Transport</keyword>
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        <location>
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    <feature type="binding site" evidence="6">
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            <begin position="43"/>
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        <ligand>
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        <source>
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        <source>
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            <dbReference type="PROSITE" id="PS50893"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
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            <dbReference type="EMBL" id="BAF87981.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="333" mass="35713" checksum="B03E32E272115B57" modified="2007-12-04" version="1">MSETPLLSVKGLRVEFRTRRGTLTAVDDVSFDLAPGEVLGLVGESGAGKSLTGSALIGLLTPPGRIAAGEVRLKGERIDNLPPEGLRHIRGRRIGMIFQDPLTSLNPLLRIGDQLTETIRTHLPLDAKGARERAIGLLEEVGIPAARHRIDHYPHQFSGGMRQRVVIALALACDPEIVIADEPTTALDVSVQAQIIGVIKRLCREKGTAVILITHDMGVIAETADRVAVMYAGRLAEIGPVRDVIAAPRHPYTRGLMGAIPRLDAEEERLVQIPGSMPQLSAIPGGCAFHPRCAHAFARCAAERPPLYAADGTSATCFLLDPAHQPEALEVAR</sequence>
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        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Ribonuclease III</fullName>
            <shortName evidence="1">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rnc</name>
        <name type="ordered locus">AZC_2004</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribonuclease III family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170531.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I3B5"/>
    <dbReference type="SMR" id="A8I3B5"/>
    <dbReference type="STRING" id="438753.AZC_2004"/>
    <dbReference type="EnsemblBacteria" id="BAF88002">
        <property type="protein sequence ID" value="BAF88002"/>
        <property type="gene ID" value="AZC_2004"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2004"/>
    <dbReference type="eggNOG" id="COG0571">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000907_1_1_5"/>
    <dbReference type="OMA" id="LTHKSCK"/>
    <dbReference type="OrthoDB" id="1890943at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0255">Endonuclease</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0507">mRNA processing</keyword>
    <keyword id="KW-0540">Nuclease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000194406" description="Ribonuclease 3">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="RNase III" evidence="1">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="1">
        <location>
            <begin position="160"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <sequence length="235" mass="25499" checksum="636B15BD1360DA28" modified="2007-12-04" version="1">MSETQDFAALEARLGHSFADRSHLVLALTHISSVKGQAVRVRSYQRLEFLGDHVLGSVVSHMLYAAFPKAEEGELSRRLAELVREEACAEVAQDMGLGPYLRLGPGEAQSGARQRRAILADVAEAVVAAVYLDGGYEAASALVERFWRGRLEAPRRPLRDPKTVLQEWAQARGLPPPVYRDVERSGPDHAPRFRVAVDLPGLECAEAEGGSKQTAQKAAASAFLAREGVVTESGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3D0</accession>
    <name>A8I3D0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative adolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2009</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170536.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF88007">
        <property type="protein sequence ID" value="BAF88007"/>
        <property type="gene ID" value="AZC_2009"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2009"/>
    <dbReference type="eggNOG" id="COG0235">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006033_0_1_5"/>
    <dbReference type="OMA" id="AFYIHAR"/>
    <dbReference type="OrthoDB" id="599627at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="33"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="266" mass="29170" checksum="879A82A8E7E03F92" modified="2007-12-04" version="1">MAHAFNRETAPQAGAAASNRPALDGEEVWNARVELAACFRFAARLGMHEGICNHFSAVVPGHDDLFLVNPYGYAFSEITASHLLVCDFHGNVLSGSGVPEATAFFIHARMHLNVPRARVAFHTHMPYATALSMVEGEPLVFAGQTALKFYGRTVVDHDYNGLALDSTEGDRIAASVGDADIVFMKHHGVMVLGRTIAEAWDDLYYLERACEVQCLAMATGRPVLPVKTEIAEAAARQMREGDAESARLHLESMKRILDREEPAYRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3F1</accession>
    <name>A8I3F1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_2016</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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            <end position="282"/>
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    <evidence type="ECO:0000259" key="1">
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    </evidence>
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        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="15"/>
            <end position="184"/>
        </location>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88284.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="205" mass="22531" checksum="6B1EA3EF5484B322" modified="2007-12-04" version="1">MGEGLRRDPIGPNAVHVCLDMQRLLAPGGPWPTPWALDVIPAITELAARAPARTVFTRFLPPEAPDGLTGTWQRFYRKWHDLTRSELDPGLLDLVPELARFVPPAHVVDKSRYSAFSGADLLPLLTHLRADTLILSGAETDVCVLATLFDAVDFGFRVILAGDAVCSSSDTGHDAIMAMLQTRLSIQVEVARTEDILNRWERPAL</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="394" mass="44206" checksum="763028D5D0D03B6B" modified="2007-12-04" version="1">MTQKRLGLIMNGITGRMGLNQHLIRSVVAIRAQGGVPLSDGTKVQLDPILIGRNADKVEGLAKQYGIERWGTDLDAALADPGNEIFFDAATTQMRPILLEKAIRAGKHVYCEKPIATNLPEAVRICRLAEEKGVKNGVVQDKLFLPGLQKLKLLRDSGFFGRMISVRGEFGYWVFEGDWGQPAQRPSWNYRSQEGGGMILDMVCHWRYVLDNLFGEVKSVSCLGATHIPSRVDERGQPYEATADDAAYATFELQDGVIAHINMSWCTRVYRDDLVTFQVDGTLGSAVAGLSDCVFQSRVGTPRPVWNPDQKQTMDFYNHWQPVPDTAVFDNGFKVQWEMFIRHVVEDAPYRFTLREGAKGVQLVECALQSWKERRWIDVPTLEASERAVLQAAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6D2</accession>
    <name>MUTL_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mutL</name>
        <name type="ordered locus">AZC_2393</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170919.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I6D2"/>
    <dbReference type="SMR" id="A8I6D2"/>
    <dbReference type="STRING" id="438753.AZC_2393"/>
    <dbReference type="EnsemblBacteria" id="BAF88391">
        <property type="protein sequence ID" value="BAF88391"/>
        <property type="gene ID" value="AZC_2393"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2393"/>
    <dbReference type="eggNOG" id="COG0323">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004131_4_2_5"/>
    <dbReference type="OMA" id="AHERIMY"/>
    <dbReference type="OrthoDB" id="764332at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0227">DNA damage</keyword>
    <keyword id="KW-0234">DNA repair</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071503" description="DNA mismatch repair protein MutL">
        <location>
            <begin position="1"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <sequence length="625" mass="67052" checksum="94A329DD67C4DF93" modified="2007-12-04" version="1">MTIRRLPPVLIDRIAAGEVVERPAAAVKELVENAIDAGATEIEVLVVGGGREMIRISDNGSGMSADELSLAVERHATSKLPTEDLLAISTLGFRGEALPSIGAVARLSIASRPKSAPHAFEIRVEGGVVTPPRPAALNGGTRVEVRDLFFATPARLKFLKSDRAEAAAAADVVRRLALARPDVAFTLMTDDRQPLTWVARSMDEAGRAARVADVLGAEAGRNLIPVVGERGGVRLVGLAGLPTYSKANSLSQFLFVNGRPVRDKLLMGALRAAYSDLLPSDRYPVLALFLSLDPREVDVNVHPAKTEVRFRDGGNVRALLVRTLTDALAARVPSTAGTIADRLVELARTPELEPARPAAAIPEFRPYRAEPMPAGGYDWRASPARPLNVAEPDGALEAEMESFAEAVQASFDVGMPAADARADAAVPETGDLDRPLGAARAQLHETYIVAQTREGMVLVDQHAAHERLVYEKLKAALERDGVARQGLLVPAVVDLDPAEADRLAERAGDLAALGLVIEPFGIGAVLVREVPALLAKADVTKLVRDVAEHSAEWDDALPLERRLLHVAATMACHGSVRAGRRLRVEEMNALLREMEETPNAGECNHGRPTFITLSLKDVEKLFARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6N9</accession>
    <name>A8I6N9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tryptophan-rich sensory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2432</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2432"/>
    <dbReference type="EnsemblBacteria" id="BAF88430">
        <property type="protein sequence ID" value="BAF88430"/>
        <property type="gene ID" value="AZC_2432"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2432"/>
    <dbReference type="eggNOG" id="COG3476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091805_2_0_5"/>
    <dbReference type="OMA" id="CIWRENP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PTHR10057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
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    </evidence>
    <evidence type="ECO:0000313" key="7">
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    </evidence>
    <evidence type="ECO:0000313" key="8">
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    </evidence>
    <sequence length="213" mass="23499" checksum="6B0EDA3938D0B062" modified="2007-12-04" version="1">MSPGCWVSVVCYGRARATDQVNRFQHLRSAGADGRLSGRTYSEDHEMTAQRIRLLSPQGLGQVALAVLPVVAASVLGQIATFPNLAPWYAGLVKPAFNPPNWIFGPVWTTLYVLMAYAAWRILRLPEATPGRSTALTLFFLQLVLNAAWSWMFFYLHSPLLGVLNIGPQWLVILATIGAFWRLDRLAGACLVPLAAWVGFASVLNFTLWQLNG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
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    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
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        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <location>
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    </evidence>
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    </evidence>
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            <dbReference type="Pfam" id="PF04143"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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                <person name="Suzuki T."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <dbReference type="EMBL" id="AP009384">
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="evidence" value="ECO:0007669"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="12"/>
            <end position="35"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
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        <location>
            <begin position="357"/>
            <end position="378"/>
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        <location>
            <begin position="20"/>
            <end position="359"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="EMBL" id="BAF88209.1"/>
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    </evidence>
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    <sequence length="387" mass="39968" checksum="0DFA5E9E688A694D" modified="2007-12-04" version="1">MSGEGQERVRLALPAAYAGLFFALGVYMPFFPLWLGERGLSPGEIGTALAVPLTTRLLATPILGWLSDRIGKPRAVLLLLAALTLLVMSALVLASGAVAIFLILGLAAMAWNPSFPLLDAYASRQARAKRVDYGRSRMWGSASFILANLLGGWLVGAAGAGVTVPLMLAGHAAFLLTLVMLPEMPRPPAAAGLHVSVPRARTALVIGILAAASVQASHAVLYAFGSVTWQKQGLSLGTIGMLWALGVVSEIVLFHFGTRVLRRLPPALLLAIGGAAAMVRFGAMTFDLPLALLLPLQLLHGATFGATYLGLVELVARAVPEHRAATVQSLAGWTVSLAMAAASVASGPLFQAFGANAFYLSVALGAVGLVAALASAALQPQRSGVGG</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF88734">
        <property type="protein sequence ID" value="BAF88734"/>
        <property type="gene ID" value="AZC_2736"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2736"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="HLLLMHE"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10938">
        <property type="entry name" value="CE4_HpPgdA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037950">
        <property type="entry name" value="PgdA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0536">Nodulation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="56"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="293" mass="33056" checksum="BE6789A030C15C4B" modified="2007-12-04" version="1">MPDNDAFARLPLAPANRAPAAPLIPWPHGKRGAMFLSADVDAESAWTSKDPARYEELVTMSFGGFEARVGVPKMLELFDQLEMKATFFITGWSVEAHPATCEAILKAGHEIGHHGFHHIMPMPGHPSLTEEVDRGLETLKRRLGVVPVGYRAPYGESCEELRVLLKERGLKYSSSWRDDVRPYRHVLADGTPGLVELPVTMTYDDWLYGLTNRYSPRPLFPREHVLSIWKDELEETADWGGLITTVLHPQVSGRPMRLKLLREFLTWVRDRGDIWTATGAEITAHFEAHEPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8I989</accession>
    <name>A8I989_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2758</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171282.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2758"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF88756">
        <property type="protein sequence ID" value="BAF88756"/>
        <property type="gene ID" value="AZC_2758"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2758"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042257_1_0_5"/>
    <dbReference type="OMA" id="FHLDYYP"/>
    <dbReference type="OrthoDB" id="694191at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="167"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="352" mass="39555" checksum="B7F750216B1D1817" modified="2007-12-04" version="1">MKIAQIAPLTEAVPPTLYGGTERVVSWLTEELVALGHEVTLFASGDSRTSARLEAMWPRALRLDGTVRDPNALHMAMIEHVYRRAGEFDIMHFHLDYYPFSLMSRQPTPFVTTLHGRLDLPEHQPLFQTFSSLPVVSISDAQRRPVPNANWVETVHHGLPVDLLGPKPAEPRYLAFLGRISPEKRLDRAIRIAQRCGLPLKVAAKIDRADEDYFNDQIRPLMGDPNIEFVGEIGDAEKPEFLSGAIALLVPIDWPEPFGLVMIEAMACGTPVIAYNRGSVPELIEDGITGFIVEDEISAAGAIRDLPAISREGVRRRFEQRFTSRRMAEQYLSLYRRLMDRGRMRPHLVSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9D4</accession>
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        <submittedName>
            <fullName evidence="3">Putative hydroxypyruvate isomerase protein</fullName>
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        <name evidence="3" type="ordered locus">AZC_2776</name>
    </gene>
    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hyi family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171300.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2776"/>
    <dbReference type="EnsemblBacteria" id="BAF88774">
        <property type="protein sequence ID" value="BAF88774"/>
        <property type="gene ID" value="AZC_2776"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2776"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR026040">
        <property type="entry name" value="HyI-like"/>
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        <property type="entry name" value="Xyl_isomerase-like_sf"/>
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    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
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    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="2">
        <location>
            <begin position="21"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="264" mass="29397" checksum="0ED58714964A3A5F" modified="2007-12-04" version="1">MIRFAANLHSLFTELPFLDRFAPAAEAGFAAVEFTFPYDVPADRISERLQRHGLKAAMLHLPAGDWAAGDRGLACQAERFDEFRATLEQGVAYARTIGAGKLVMMAGLGSRQDPQAEASFRRAVAFAGERLEREGLCLLLKPLDPREIPGYFLTDFCHVADLVAELGVPHVKMLFDVYQRQLARGDVAMALRRRIKQIGHVQVAAVPDRGEPDDGELNYAYILRRLECLGYDGYIGCDYRPRGRSTLAGLGWMKPYLPRVRAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9E6</accession>
    <name>A8I9E6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171304.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2780"/>
    <dbReference type="EnsemblBacteria" id="BAF88778">
        <property type="protein sequence ID" value="BAF88778"/>
        <property type="gene ID" value="AZC_2780"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2780"/>
    <dbReference type="eggNOG" id="COG0667">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023205_5_0_5"/>
    <dbReference type="OMA" id="YELDYDN"/>
    <dbReference type="OrthoDB" id="1054546at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42686">
        <property type="entry name" value="PTHR42686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="10"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="337" mass="36234" checksum="7EFE386FBE1499C7" modified="2007-12-04" version="1">MALKDILPGRLGFGAAPLGNMFRDIPETEALATVEAAWNDGIRYFDTAPLYGAGLAEIRMGEALAGRPRADYVISTKVGRVILDEVEEMSARDLGEKGDVFKYGRPNKIVNDYTADATLRSIEDSLKRLKTDHVDIVFVHDVAQDFWGDAWLGRFEEARTGAFRVLDRLRDEGVIKAWGLGVNKVEPIELLLGLEGPKPDAFLLAGRYTLLDHSRALQRVMPQVAERGLGIVVGGPYSSGALVGGPNFEYAPITPAMAQRVARIKGIADRHGVSMKAAGLQFSLANPAVAAVIPGASRPARIAEDGAALREVVPADFWRELRTAGLVDPAAPLPGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9V0</accession>
    <name>A8I9V0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2835</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2835"/>
    <dbReference type="EnsemblBacteria" id="BAF88833">
        <property type="protein sequence ID" value="BAF88833"/>
        <property type="gene ID" value="AZC_2835"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2835"/>
    <dbReference type="eggNOG" id="COG2239">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037408_1_0_5"/>
    <dbReference type="OMA" id="TMTVAVR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="227"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="474" mass="51374" checksum="D95E48B0EB94C87D" modified="2007-12-04" version="1">MRRRAMREEAEAVDVATLLPPIRDADDAISEAFLAAVEAGLAEGPSDELRARLRDLHEADMGDLLEALPAEARVRLVETLGADFDFTALTELDETDRVGLLSHLPPLMVAEGIRTLESDDAVYILEDLDADDKAAILAHIPAPERVALQRSLDYPEESAGRRMQTDFIAVPPFWTVGRVLDYVQQTDDLPETFYEVFVVDPAYHLMGAVPLDRLLRTKRSVLVTAVKTERVQVVKASEDQEEVARTFERYNLVSAPVVDDAGRLVGVMTIDDVVDVIQEEADEDLRALAGVGSDEELSDTVAYTAKSRLPWLVVNLGTAFLAASIIDLFAVSIEKMVALAVLMPIVASMGGNAGNQTMTVAVRALATRDLGSHNARRIVLREVLVGLANGLALACLLGLIAALWFGNWQLGGVIACALVINMLAAGLFGILIPLTVHYFRQDPAVASGVFVTTVTDTVGFFAFLGLASLWFHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAD5</accession>
    <name>A8IAD5_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2495"/>
    <dbReference type="EnsemblBacteria" id="BAF88493">
        <property type="protein sequence ID" value="BAF88493"/>
        <property type="gene ID" value="AZC_2495"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2495"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_2_2_5"/>
    <dbReference type="OMA" id="MARSENN"/>
    <dbReference type="OrthoDB" id="916788at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="77"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="266" mass="28268" checksum="A70240C559D7229A" modified="2007-12-04" version="1">MAMAPARTLPHRGGWRVAMPSPSRVALYQIALLLALLALWEAGVALGWLPVFLYGRPSGVIAKGWQLILSGELARDAALTAWEAISGFAIGTVLGSAAGLTLWLFPTGAAVLRPYMIALNGLPKIALAPLIIVWFGIGLGSKIAIAAIITFIVALITAQQGAKEVDADLVKLMRSLGASRLRTWRTVIVPGAMPWIVSAFRLNVGFALIGAVVGEYIASKEGLGYMIYYAGVLYDLNAVWVGIAALMGVALAMYGVIDLIERRLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAJ0</accession>
    <name>A8IAJ0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative arabinose efflux permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">araJ</name>
        <name evidence="7" type="ordered locus">AZC_2514</name>
    </gene>
    <organism evidence="7 8">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171040.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2514"/>
    <dbReference type="EnsemblBacteria" id="BAF88512">
        <property type="protein sequence ID" value="BAF88512"/>
        <property type="gene ID" value="AZC_2514"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2514"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_61_5_5"/>
    <dbReference type="OMA" id="LYCVQPM"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="3"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="402" mass="41619" checksum="3DACC364DD768E6D" modified="2007-12-04" version="1">MSFLLILGLADFASAFTARSVDPMLNLLASDLGVSLQAAALLATAFTLPYALMQLVFGPIGDAFGRVRLIRITLACLTIGHLACALAPNHPVLVAARVFAGGWAGGIIPVSFAIVGDRVAFEQRTVALGRLLLAVVLGQLGGAIISGTLATYFGWRTVFFAAAAVSAAATLCTILFLKELGARKPISVAATLEGYRTVFRNPVSIRHFAVSAVEGGIIFGVFPFVAPLMVEFHIGDAVEAGIAMGAFAIGGVLYSVVVQKLVDLLGLSGMAATGALIVGCCLIGIAFAPSLVFMMALFGVMGFGFYTIHNTLQIMSTELAPSARGSGVSLYATFFFAGQAFGAVVAGAVSHAVGSLPGMFVVAGLAMFALAWPASRLAPLAERVRREAEETAARKVQSVEPV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAR8</accession>
    <name>RL2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplB</name>
        <name type="ordered locus">AZC_2551</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171077.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAR8"/>
    <dbReference type="SMR" id="A8IAR8"/>
    <dbReference type="STRING" id="438753.AZC_2551"/>
    <dbReference type="EnsemblBacteria" id="BAF88549">
        <property type="protein sequence ID" value="BAF88549"/>
        <property type="gene ID" value="AZC_2551"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2551"/>
    <dbReference type="eggNOG" id="COG0090">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036235_2_1_5"/>
    <dbReference type="OMA" id="SCIELRP"/>
    <dbReference type="OrthoDB" id="961486at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022671">
        <property type="entry name" value="Ribosomal_L2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00467">
        <property type="entry name" value="RIBOSOMAL_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000073226" description="50S ribosomal protein L2">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="223"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="277" mass="30083" checksum="54549B9989790088" modified="2007-12-04" version="1">MALKHFKPVTPGLRQLVIVDRSGLYKGKPVKTLTEGKSSSGGRNNNGRITVRFRGGGHKQTYRLVDFKRAKRDVSATVERLEYDPNRTAFIALIKYEDGELAYILAPQRLAVGDKVIAGEQVDVKPGNAAPLSNLPVGTIVHNVEMKIGKGGQIARSAGSYAQIVGRDQGYVIVRLNSGEQRLIHGACYATVGAVSNPDHMNTSLGKAGRSRWLGVKPHNRGVTMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGMKTRSNKATDKFIVTSRHKRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB27</accession>
    <name>A8IB27_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="9 10" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <topology evidence="1">Peripheral membrane protein</topology>
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    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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            <dbReference type="EMBL" id="BAF88627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="367" mass="39513" checksum="611E11593EEE47FA" modified="2007-12-04" version="1">MTPSPLSPKHGVAMAAIPNDVDPRDRGGPAQPLLIVEGLKKHFPIRGGLLGRPQAWVQAVDGVDLTVAKGETLGIVGESGCGKSTTARLLMHLMTPDAGDVIFDGDLVGAMRGLSVRDLRRQMQMVFQDSYSSLNPRMTIEDSIAFGLISQGKGQKEAKTRAASMLRMVGLTPDLFAPRYPHELSGGQRQRVNIARALTMGPRLLILDEAVSALDKSVEAQVLNLLQELKQKLELTYIFISHDLNVIQYISDRVMVMYLGKAVEIGPVDEIYRSPKHPYTRALLNSRPSMDPRRRMAAPPLSGDPPNPINPPSGCRFRTRCPIAEAVCSAVAPALEAADGEAAHPVACHAHRAGSGHTAAPSEGAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB96</accession>
    <name>A8IB96_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Oligopeptide/dipeptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171154.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2630"/>
    <dbReference type="EnsemblBacteria" id="BAF88628">
        <property type="protein sequence ID" value="BAF88628"/>
        <property type="gene ID" value="AZC_2630"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2630"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
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    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="13"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="341" mass="36694" checksum="6BBAA5F5A7792094" modified="2007-12-04" version="1">MSSQASAADAPLVEVENLTVRFTGRDLDVSVVNGVSFTLDRGSSLCILGESGSGKSVTMRALMRLFPPTARLEGKVRVDGIDVLALEDHQLRRIRGGLISMIFQEPMTALDPVFTIGQQIGETLVYHEGISYRAAYARALQLLELVQVPSAKRRLEAYPHELSGGLRQRAMIALALACQPKLLLADEPTTALDATVQIQILLLLREIQREMGMATIFVTHDLGVACEVADKIAVMYAGKFVESGSVEQVIDSPRHPYTQGLMNSTIHADMRGVALDPIPGAPPDLADLPPGCPFAPRCAAAREPCLEQAPELTLLPGGQKARCLQYEAGAAFTQAPLLKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBV0</accession>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3122"/>
    <dbReference type="EnsemblBacteria" id="BAF89120">
        <property type="protein sequence ID" value="BAF89120"/>
        <property type="gene ID" value="AZC_3122"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3122"/>
    <dbReference type="eggNOG" id="COG2202">
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000445_114_71_5"/>
    <dbReference type="OMA" id="GFAFHWQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
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        <property type="entry name" value="His_kinase_dom"/>
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    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
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    <dbReference type="InterPro" id="IPR035965">
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    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="537"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="475"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="763" mass="83683" checksum="270A50F9794D3318" modified="2007-12-04" version="1">MARANAASVGARGDAIGGLARSVARPAYQRLLEAEPFLRRIVPALIITFLVVLGIGALVQVHTHRQSVLDNAKDDLALQALATAEGLNHRLNGSLANTGSALLAALPPRATSGGRRIYVTDPSGRVIAAAPESAPRVTSLADLMDPSQPLTVFAERAGVLEIAVGDTQMLATVRNLNPPLGQIVYLQPMNRALAVWSDSTTLTITLFATTGAVLLILGFSFHWQASRAREADHIYDTVRMRIDTALNRGRCGMWDWDMARGRMYWSDTMFEILGLERRDELLSFGEIAKLVHPDDGNLYELAQELAERPGASVDRVFRMRTARGDFVWLRMRAEVVQQAGEDGPHLIGIAMDVTEAQRLAERTVTADMRLRDAIESISEAFVLWDSQNRLVLCNSKFQTLHELPDDAIVAGTPFETIATVGRHPVTRTPLKPEDKPEEGSRAFEAQLSNGRWLKIAERRTKDGGYVSVGTDITPLKRHEERLMDNEKRLMALVADLRKSQQTLEHQAQQLAELAEKYSEEKTRAEDANRAKSEFLANMSHELRTPLNAIIGFSEIMESGMFGPLGSDKYREYCSDIKGSGTYLLDVINDILDMSKIEAGRMQLELEDIRLDEIIADAMRVTAVKGDEKQLDMTAQVGAGQVMRGDRRALKQILLNLLSNAVKFTPEGGHVAVRAKVNGGAAVIAIEDTGIGIPRHALNKIGRPFEQVESQFTKTHKGSGLGLAIAKSLAELHGGSMRIRSTEGAGTTVVVRLPIHGVPHLSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC84</accession>
    <name>A8IC84_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoprotein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_3174</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nlpA lipoprotein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3174"/>
    <dbReference type="EnsemblBacteria" id="BAF89172">
        <property type="protein sequence ID" value="BAF89172"/>
        <property type="gene ID" value="AZC_3174"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3174"/>
    <dbReference type="eggNOG" id="COG1464">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067080_3_0_5"/>
    <dbReference type="OMA" id="HVEPIGF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004872">
        <property type="entry name" value="Lipoprotein_NlpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30429">
        <property type="entry name" value="PTHR30429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03180">
        <property type="entry name" value="Lipoprotein_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002854">
        <property type="entry name" value="MetQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="296" mass="31961" checksum="B7940442A8A55196" modified="2007-12-04" version="1">MPARTFVDRLSQHSDSSHAKGKGMSLLHGLRKSVLALAGILALVASEGAVAQTADKPLKVGVSAGPYGDILREAAKVAAKDGLKAEIIEFTDWNQPNAALQAGDIDLNNFQHRFYLANQIKARGYQLVALDESILVPAGLYSKSYTKIADIPDGAKIAIPNDPTNAARALLLFQRAGLLKLKPTTGLNATVLDVESNPKKLQILEIDAAQLPRSLDDVAVAFVSSNYAYLAGLSLRKALLAETEVAESKPYFTLIFAACEDRKDDPRIKAFIAAYRSQAVKDFIVEKFNGTIQPAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICG8</accession>
    <name>A8ICG8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Putative ABC-type bacteriocin/lantibiotic exporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_3207</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171731.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3207"/>
    <dbReference type="EnsemblBacteria" id="BAF89205">
        <property type="protein sequence ID" value="BAF89205"/>
        <property type="gene ID" value="AZC_3207"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3207"/>
    <dbReference type="eggNOG" id="COG2274">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_95_5_5"/>
    <dbReference type="OMA" id="VRRQCGV"/>
    <dbReference type="OrthoDB" id="643917at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022515">
        <property type="entry name" value="NHPM_micro_ABC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03797">
        <property type="entry name" value="NHLM_micro_ABC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="544"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="639"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="408"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="721"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="755"/>
            <end position="762"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF89205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="958" mass="101869" checksum="A1351F709142958A" modified="2007-12-04" version="1">MSGALHGPGAAAETAFPVVGNAPLLLDDPCACYRVTAGEAQIFLVEVLEDGRPGTRQHLFDAARGDLLFGLDTALSLPPVKFLAIGSPGTEVVALSRETVAADTQMASGIDTWIIRLSRAISRQIVPRPRFDLPLGSGETTTLPRGGKITSAQGVAWCRASGGLYVDMELTEAHAPVPVTPDSWISLDPDGTITAQETADLMAAGALLPALDRFHALAVDVLPMALRLASVDELNRLRERAAQDRRSAGGALEVLGSVLGQGRRRSEPPPSDQPLVLALAHLGSVAGFEVRLPARRDHEPRPFELDALARASRLRLRHVRLEAGWWRHDSGAFLLMRAAPLPPLAVVPARGGYEIFDPEERTVRRLPAAEAAALSGDAYMLYPALPDRPVSLRQVAARIVSARVRDLAALAGATLLAGVLAMAVPLAISYLVSSVIPDNNAGKIAQVAAALSVLAVMNFVLRLASQLVVLRIEGLEGSRLQAGVMDRMLRLPTGFFRSFTAGDMGTRVMAVARLEKALTASLVGSVMTGMMAIISYGVMLAYSWRLALVAILLTLLLAAGTLVLGLIRIRYEAQAIREDARMSGLTLELAAGITKLRLAAAEDRAFYRWARLYAAASRSQLDADRAASLLNTLSEGYPAFAMAVLFAACIYGGLVDSIGLGLLVGFAIAFSSALEGLRGLAQAAVEVVALAPIVAHAAPILHATPEVDGEKMDPGELSGAIEISRLTFQYQPDAPRIFDDLSITIRPGEFVAFVGPSGTGKSTLFRLLLGFEQPASGVVLYDGVDLAGLDIQAVRRQCGVVLQGGKLMPGTLMDNILGSASHLGPDAAWEAARHVALEEDIRRMPMGLHTVITDGGTGLSGGQIQRVLLARAIVSKPRIMMLDEATSALDNRTQAAVTESFNRIAGTRLVIAHRLSTIARADRIIVLNNGRVEEEGSYDALMARNGFFTAFAQRQLTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICV5</accession>
    <name>A8ICV5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">plsY</name>
        <name evidence="11" type="ordered locus">AZC_2849</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171373.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2849"/>
    <dbReference type="EnsemblBacteria" id="BAF88847">
        <property type="protein sequence ID" value="BAF88847"/>
        <property type="gene ID" value="AZC_2849"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2849"/>
    <dbReference type="eggNOG" id="COG0344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081254_1_0_5"/>
    <dbReference type="OMA" id="WRHRGNL"/>
    <dbReference type="OrthoDB" id="1691856at2"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00023">
        <property type="entry name" value="TIGR00023"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="207" mass="21481" checksum="93F778423B3C7AB8" modified="2007-12-04" version="1">MPASVPFLAEIPLTLALAALVLGYLLGSIPFGILITRFAGTQDIRTIGSGNIGATNVLRTGRKDLAAATLLGDALKGTAAVLLARHFWGEPAALIAGLGAFIGHIAPVWLKFKGGKGVATFLGIALGLFWPSLVVFAVVWLGMAFLFRYSSLAALTASVATPLSAWALGRADVAVLMALLAVLLWIKHHANISRLLSGTETKIGAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID54</accession>
    <name>A8ID54_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">iclR</name>
        <name evidence="5" type="ordered locus">AZC_2884</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2884"/>
    <dbReference type="EnsemblBacteria" id="BAF88882">
        <property type="protein sequence ID" value="BAF88882"/>
        <property type="gene ID" value="AZC_2884"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2884"/>
    <dbReference type="eggNOG" id="COG1414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062618_1_0_5"/>
    <dbReference type="OMA" id="QHASLFH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="33"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="95"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="284" mass="31035" checksum="776F17FEA7D3A232" modified="2007-12-04" version="1">MCIVYDTKRDRGIRRDGEMADDRDATPEKSDGVRALRRGLAVLRHINACGSTSAAEIARALSIPRPTVYRLLQTLEEEGYVAFSASSTQVRVTRLAASLGDGYAAQARICQAAGPVFGHYAPRLVWPLDLTVYEDAAMVIQETTHTRSPLSIDRGMIGFRLPMLRTSAGRAYLAYCPPEDRQAILGHLRRMDDGEDRPFLDDAWLARCLSETRKNGFAVRDGGEFRPKTSSIAVPVMVGQRVEAVVSMIWIRSALSLAEAIRAHGRTLAEVASAIAQAGAPPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IE31</accession>
    <name>A8IE31_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="293" mass="31395" checksum="7439A2255D5A7B10" modified="2007-12-04" version="1">MRAVQVIGKVAPHAKPEYVAAFAQGDAALLAAQVNTPLRLAHLLAQVLHETGGLTIVRESGSYTAPRIEQIFGIGHHSAAVTPIEARQLAGNGVALFERVYGLGNPSMARQLGNTQPGDGWAYRGNGLLQTTGRGQHREMGRLSGVGDLFEEDPTQVIHPEHALKPALAEWTRGACNLLADQGNVRQLTRTINGGYNGYAERVAWLNRIWAVLGTGAPWEAAAPEFSVSDLQSKLNRLGYRLTADGRYGPKTEEAVRDFQSKNDLKTDGIAGPVTLAALEARLLPALAERSAA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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            <dbReference type="ChEBI" id="CHEBI:15361"/>
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    <comment type="pathway">
        <text evidence="1 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
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        <text evidence="2 11">Belongs to the pyruvate kinase family.</text>
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    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
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            <dbReference type="EMBL" id="BAF89489.1"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="149"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="460" mass="51500" checksum="6B8E7044F25C6E43" modified="2007-12-04" version="1">MPAVQETVERVRSIDVDQYKYGFVTDIESEKAPKGLNEDTVRYISAKKNEPEWMLEWRLDAFRRWLTMEEPTWARVSYPKIDFQDYYYYAQPKAKPKSLDEIDPEILATYDKLGIPLREREALLGIESGSRPIAVDAVFDSVSVATTFKAELAKAGVIFCSISEAIREHPDLVKQYLGSVVPVSDNFYATLNTAVFSDGSFVYVPKGVRCPMELSTYFRINERNTGQFERTLIIADEGAYVSYLEGCTAPQRDENQLHAAVVELVALKDAEIKYSTVQNWYPGDKDGKGGIYNFVTKRGDCRGDNSKISWTQVETGSAITWKYPSCILRGDNSQGEFYSIAISNGFQQVDSGTKMIHLGKNTSSRIISKGIAAGRSENTYRGQVTAHRRATGARNFTNCDSLLIGDKCGAHTVPYIEAKNASAVFEHEATPPRSPRTSCSIVCSAASRRRRRWRSSSMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFJ2</accession>
    <name>A8IFJ2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3621</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3621"/>
    <dbReference type="EnsemblBacteria" id="BAF89619">
        <property type="protein sequence ID" value="BAF89619"/>
        <property type="gene ID" value="AZC_3621"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3621"/>
    <dbReference type="eggNOG" id="COG3164">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007198_1_0_5"/>
    <dbReference type="OMA" id="GTFVPMY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025263">
        <property type="entry name" value="DUF3971"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13116">
        <property type="entry name" value="DUF3971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3971" evidence="3">
        <location>
            <begin position="538"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="4">
        <location>
            <begin position="1051"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1208" mass="127343" checksum="51FF35EC720F6DDC" modified="2007-12-04" version="1">MWGHVLASRTGLVILPAVRHGARGRARVLPEDAEGMSEDRGQLKPAVRMPRRSRLHGLAGALIPRSRPARIATGLFLGLIGIAGLAALVLYFLIAQGVVTANLATPYIERAIEERLDGKYKVRIGSTAVETMSGGATLVIARDISVTEPDGTVVASAPSAEVELDGSLLTLSLKARRFDLIGAEMTLRIGAKGELAVAAGKGARPISAGAAPVEPGGNAPPVVPQAQPSQAPAAPGAVPGSVPAPQAADLGGDPLVLRALAQGLNALESNGFDGGALSDIGLKNGSLVVQNEATGRQITFDNMSIRLGRTAEGGATFTFTSQQPHGLATLVATIAPARNGERQIDFELKDVSTQDLVQAFSQDLKRFYMDTPLGASLRARIATDGRVLAAEANVVLGAGQIGNGEEPEERFVIDRAEARLTLDPAKRVIVVEPLMAVKNQNRIALKGLITVPALAAQPWPYAISQVGVVLAGPEMPDPALVFTGVTIAGRFTPPDRKLLIDQGELTSAVGSLSFTGLFDFGVDVPYIQMKATGSRMPASTVKRFWPVTLAPPARTFVIENVSAGMVEGTTVTVKMALDLIGQKSVPLPDDAVRLEMNASAVTLRPVKGLPPVSNAKLNIVVTGRTVRVNIPEGTVVTPQNRRLALSEGVYYMPDYFPREPSGLVKVKFDGPADAAIEILGMDPIKGSEGQAFDPSTTRGKVSALLQVKILFRKVPQPGDVDYSLEAKLTDFGVDKIFQNQRLEGASVDVFASPAGVQLRGDGKIAGALVTFDYNKRKDKADSDVRVNATLDDGSRQKLGLDIPAVTGPIAVKLVGTTNNTQTKAAIELDMTAARILDLVPGLSKPAGDPLKAKFNSNDAGKSLKIDDLTLEGSGTYIRGSIEFSDDNQILSANFPSFQLSDGDKASLKADRSGDVLKIRISGEVMDARGILKSLVSTPSGAKNTQKTPDVDVEAKIGAVTGNNGEVLRQVDLAMGRRSSELRSFALTAKAGREGTLAGEIRNWGDTPRRALYVSTSDAGAVLRFLDIYKKIQGGTMWVIVDPPRGDNAPQNGVINVRDFVVRGEPGLDSLSQAARDSSGRVEQGTAVFEKAQAQFTRTTGKISFRDGAIWGPVAGATFDGTIDFAAERINMRGTYVPAYGLNNLFSKLPILGNILGGGPNEGLVGVTFEVAGPMAAPALRINPLSAVAPGFLRKMFEFRSSTETAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFS9</accession>
    <name>A8IFS9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3647</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <dbReference type="STRING" id="438753.AZC_3647"/>
    <dbReference type="EnsemblBacteria" id="BAF89645">
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    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_005887_4_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
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    <dbReference type="GO" id="GO:0019867">
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        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724403" evidence="1">
        <location>
            <begin position="50"/>
            <end position="1176"/>
        </location>
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    <feature type="domain" description="Autotransporter" evidence="2">
        <location>
            <begin position="891"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1176" mass="116782" checksum="895D5202C4D9D127" modified="2007-12-04" version="1">MGAIVMNAVGRSAGTAHGGAMSRGSRRAMRRAWLAVMLASVALPPAAHAADALTWSMYNSYSQSYFIEYARGLSGALSNATTMNFNVSVAGHTLYPTMDTGSTGLVISANVLGLSTTAPVNAQAGWVFYNSSGLLLTGYFSQQNVQFSGKDANGAATPVVSNVPVLVVTQAQCLGVGANSSTCDAATSVNGVQMMGIGFDRNTMGTGVVNTSNPTAAAARLDAAPTTPQIYNPFLNVVTSGSGAYRNGYIITPTGVYLGLTEANTSAQAYSYAQLALAPKQTAGAPQWLATTVTVTVTTPAGASTPASSASGKGTLLMDTGVEDAFIGIPNGGSITPASNTVVTLQLGNGIGTYSFTVPSSTSPASTNPQTPTRVSFFDSSSGFINSGLHTYAGYNVLYDADGGFIGLALNNYPGSTAQVTQMIAAQGTLNLTSDFATNLPVLLIANATVATASGSTATFNSDFTGTGQLTLQGGSVTLNGQLTHSGGTVVASGTTQLGGTLIGSLSVLAGATFLDASGGYTVAAGRTLSNAGTFTGPSSVSVSNAGTVVNSGTFAVSFSNSGTATNTATGAFTANIANSGVFLNAGSIAGNVTNTGQFTSAATGTIAGTVQNSGRFTNNGSIGPGAATPPAIVANTGVFVNAGGITGNVSNAGQFTNNGTITGTVENTGTFGGNGTVGHLLVRTGGALSPGNSIGTHVVRENATFEPGAVLLAELGTPGTSDRLIVGGTLTAGGAVLVPIPGEGFAPALGAGYRVFSAGTTASNFTVGGPYFGTAGAVYPFLSASLGSGADSGLLTLNRSAVSYAALAPTANAAAVGRAADTVALAQPLGQALAVMPGAAAPAALASLSGEIYASAQGVLQVQSSYVRNAVTGRLAQAEGAPGTAQLAPVDGFGTTLWGQAYGGWGSTASDGNASAVTRSLTGFLIGLDGRLSDWRVGVAGGYSQSDFSTDSLPGSGTSDNYDLALYAGRTFGGDANGAFALRAGAAYGWHDLSVSRTVTAPGLVAGYGTGYSAGTAQVFGELAYTYAPRTEGLPVSLEPFAGLTYTALSTNGFTEPFGPAALRAQSASFDTLSTTLGLRARTTVQVGAVPVALTGSVGWQHAFGDVTPTTTFTFAAGSLPFTVAGAPLATDALLLGLGAGAKLADNLDLSLAYNGQIASGFTETAVKGILSWRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFU6</accession>
    <name>A8IFU6_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Rhodanese-like protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3652</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172175.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3652"/>
    <dbReference type="EnsemblBacteria" id="BAF89650">
        <property type="protein sequence ID" value="BAF89650"/>
        <property type="gene ID" value="AZC_3652"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3652"/>
    <dbReference type="eggNOG" id="COG0607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089574_6_3_5"/>
    <dbReference type="OMA" id="GGMLGWK"/>
    <dbReference type="OrthoDB" id="2056793at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="24"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="113" mass="12044" checksum="303796F9F11C9CA3" modified="2007-12-04" version="1">MSEINPFGGRVVHLTPADVKAGLEDGTILLVDVREPNETTAERIPGSVLFPLQTFDASALPDPQGKRLVFSCRSGQRSQKALALAQAAGLPYEEHMQGGILGWKEAGFPTDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH40</accession>
    <name>A8IH40_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">TRAP C4-dicarboxylate transport system permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dctM</name>
        <name evidence="5" type="ordered locus">AZC_0170</name>
    </gene>
    <organism evidence="5 6">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
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        </location>
    </feature>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="425" mass="44986" checksum="2C6C28088443B96D" modified="2007-12-04" version="1">MLSRPLAILSRVRLAALAAVAALALAACNGQGNDVSAKANQPLSPKMISLMSEKDMAPQNPILIRVFKEEAELEVWKAKNDGSYALLKTYPICRWSGELGPKVKIGDRQAPEGFYMITPGLMNPNSSYYLSINTGFPNAFDKSWGRTGEFLMIHGDCSSAGCYAMTDEQIAEIFALAREAFAGGQRAFQIQAMPFRMTPQNLARHRNNPNMAFWRNLKQGYDHFEVTKHEPKVNVCNRQYVFDAQLQPGQAFNPSAPCPAYTVAPEIASAVGAKERSDNLKVAELSSNTPLAPVRTGRDGGMNPVFLAKLNGEDNAPARMAYGQDNVPAFDPANVRPPKADGEVVAAPVRPGAPAATPAPAPVASAPARAASTPYPNGTAAPTAGSTSSLYTRATTQTASADTGVAQASALMGAAPIVGSGGFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <text evidence="1 6">Belongs to the glutaredoxin family. Monothiol subfamily.</text>
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        <location>
            <begin position="16"/>
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        <location>
            <position position="29"/>
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        <ligand>
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        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
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            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
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            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
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            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transferase hexapeptide repeat family.</text>
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    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="36"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018522"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89458.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="297" mass="31739" checksum="8DA0403F828D0731" modified="2007-12-04" version="1">MLEGRSLTFREAAMLQHGFQATKPANDRRPELVDPVWARLCREAEEAAAREPMLAGFLKGAIVSHETLEGVIAERIAARLDHPDLPGYAIRGAYREAVAADPSLSQALRADIMAVVDRDPATTRVLEPVLYFKGFHALQTHRLAHWLWENGQRDAALYLQSRVSAVLQVDIHPAVPMGRGIFLDHATGLVVGATAVIEDDVSILQGVTLGGTGKERGDRHPKIRRGVLIGAGAKVLGNIEVGHCARIAAGSVVLHPVPPATTVAGVPAKVVGSAGCAEPSRAMDQMFDVEIYAGADI</sequence>
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        <name evidence="1" type="ordered locus">AZC_0227</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168758.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0227"/>
    <dbReference type="EnsemblBacteria" id="BAF86225">
        <property type="protein sequence ID" value="BAF86225"/>
        <property type="gene ID" value="AZC_0227"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0227"/>
    <dbReference type="eggNOG" id="COG0251">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_100715_4_1_5"/>
    <dbReference type="OMA" id="RHALYEE"/>
    <dbReference type="OrthoDB" id="1850770at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="CDD" id="cd02198">
        <property type="entry name" value="YjgH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038743">
        <property type="entry name" value="YjgH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="132" mass="14442" checksum="04348452D72A49B5" modified="2007-12-04" version="1">MRTSEALFPAGRQALYEINRYSAAIRSGDLLFVSGQVGSRSDGSPEPEFEAQVQRAFDNLAAVLKAAACTFDDIVDVTTFHTDPERQFEAVTAVRTKAFPQAPYPNWTAVGVTWLAGFDFEIKVIARVPQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ97</accession>
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        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
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        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_0271</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="BAF86269"/>
        <property type="gene ID" value="AZC_0271"/>
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    <dbReference type="KEGG" id="azc:AZC_0271"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="LysR_subst-bd"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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    <dbReference type="InterPro" id="IPR037402">
        <property type="entry name" value="YidZ_PBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="324" mass="35319" checksum="FF42EF4BDBA50BA3" modified="2007-12-04" version="1">MDIDLNHIRRFDGALLLVFRELMATGQTTAAARRLGLTQSTVSHALRRLRDLTGDPLFQRRPDGLTPTPRAHELLPIVVEMLRLSQALKGEPGEFDPAASTRHFRIAGPDIVSTVLAGPLAHRFAQHAPNARLSFGFIVGAAALEALRRGEIDMAIGHFPSVPRGFAASTLWEEEFVAIARKGHPRFPPLDLAGYLAADHVLVSFSGRFTGVVDRVLQPLGLARRVVASFPLFLSVFDAVAQSDAVAAVPYSLCERHAETFGLARLPMPIAVPGFPIVSVRRAGVPDGGYEWLEALIRRMVAEYADEIEARGEWPPRQPVPAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJF0</accession>
    <name>A8IJF0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyhydroxyalkanoate depolymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0295"/>
    <dbReference type="EnsemblBacteria" id="BAF86293">
        <property type="protein sequence ID" value="BAF86293"/>
        <property type="gene ID" value="AZC_0295"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0295"/>
    <dbReference type="eggNOG" id="COG4553">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017495_0_0_5"/>
    <dbReference type="OMA" id="AVCQPCV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009656">
        <property type="entry name" value="PHB_depo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010915">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06850">
        <property type="entry name" value="PHB_depo_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020818">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01849">
        <property type="entry name" value="PHB_depoly_PhaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB_depo_C" evidence="1">
        <location>
            <begin position="203"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="405" mass="45275" checksum="EF65DB6860FAB83A" modified="2007-12-04" version="1">MYLAYQAQSDLMEPVKFGAHFARRFLSGPFMAPFQTQATRQLAAACEMVERVGLTHGRPDFGIRTTEVGNREVPVVEEGVFRMPFGTLLHFKKKDVDVAQPRVLVVAPLSGHFATLLVNTVRTLLPDHDVFITDWHNARDVPLEEGGFGFDGYVEHVTKFLEFMGPGAHLVAVCQPCVQALVAAAVMAQEGNPAYPRSMTLMAGPIDCRINPTKVNELATSKPIRWFENNLISTVPMGFPGSGRRVYPGFVQLSAFVSMNFGRHMKAHFDLYDALVEGDEEKATTTKVFYDEYFAVLDLAAEFYLETVQYVFQEYRLPKGELTYKGNPIDFKAIRRTSLLTVEGERDDICSLGQTVAAHDICTGLKPHRKRHHMQAGVGHYGVFSGRKWAGQVYPIVRNHILASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK78</accession>
    <name>A8IK78_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Putative ABC amino acid transporter permease/substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_3871</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3871"/>
    <dbReference type="EnsemblBacteria" id="BAF89869">
        <property type="protein sequence ID" value="BAF89869"/>
        <property type="gene ID" value="AZC_3871"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3871"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_0_5"/>
    <dbReference type="OMA" id="IGRGQWQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="26"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="227" mass="24918" checksum="922B0C772169AF6F" modified="2007-12-04" version="1">MRGPGAAMDFDAAYLAQQWPALMGGLWVTCQVTLLSIVLSLLIGLFGAAFRLFSVPILSQLTFGYVELVRNTPILVQLFFIFYGLPAIGLGISQFWSGVLCLSLWAGAYQVENIRGGLLTIEKGLKEAAFSLSLSLRQYFRLVALPLAIRTSLPSMLNTSISLLKNSSYLQAIGLAEMTFIAVDRIATDFRAVEMFTAIGALYLALVIVLSLMTSIVEHKLRKPFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK87</accession>
    <name>A8IK87_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_3874</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172394.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3874"/>
    <dbReference type="EnsemblBacteria" id="BAF89872">
        <property type="protein sequence ID" value="BAF89872"/>
        <property type="gene ID" value="AZC_3874"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3874"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="EGTTMLM"/>
    <dbReference type="OrthoDB" id="1191583at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="249" mass="27036" checksum="3D55E1D6E94F9B99" modified="2007-12-04" version="1">MNGAGRALVQVRGLYKAFGAVTVLHGIDLDVKEGEVVVIIGPSGSGKSTFIRCINGLEAPTAGRITVEGHMAEAGNRKALDALRSDIGMVFQDYTLFPHLTVLENILLAPRLRGRLKGEAALRRVMELLDLVRLPHKAQAYPAELSGGQQQRVAIVRALAMSPRVMLFDEPTSALDPETVADVLVVMRDLAVRGMTMMIVTHEMGFAREVADKVVFMDGGKIIEEGPPAQLFGNPQQARTRAFFGKILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKG2</accession>
    <name>A8IKG2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Error-prone DNA polymerase</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dnaE2</name>
        <name evidence="13" type="ordered locus">AZC_3904</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
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            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
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            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-C family. DnaE2 subfamily.</text>
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        <property type="match status" value="1"/>
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    </dbReference>
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    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
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    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="12">
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            <begin position="29"/>
            <end position="92"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL15</accession>
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    <organism evidence="2 3">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <dbReference type="EMBL" id="AP009384">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3976"/>
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        <property type="gene ID" value="AZC_3976"/>
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    <dbReference type="KEGG" id="azc:AZC_3976"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
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    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF55729"/>
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        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <evidence type="ECO:0000256" key="1">
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <sequence length="752" mass="80350" checksum="FD641A7733708557" modified="2007-12-04" version="1">MDRWHGTMGRSAAGSAAALAEPVYAPEPHDGWSDGGHLRAVATPGAADHPLYAPADQPEDILDPAGTGFTRALAESVAILARKVDVLGAKAVDPVAIARLQRQTGELKELVERVLVLHERSASDAAAASASDEFTRLAMDALARLETRVDGFMAEQARRTAPSEELTVLRERLDAVAHDVKALGSAGDPRFAARLEDLLARFDRNETIEAAKLAPLVDVLERHLSRLVERVDETQVHVARLDGIEAMLQGLTRELQRLQEPADDEVAAPQDDIAYGADEALVPHETAVLAPHLTLVEEDWRSPVETQAPAGTDPAGLREQDLPLRAAEIRPQVQEAAPPAAPAAAPSLEEWPQWPTDLRREPAPRAEPRPEIARDPAWQVTEAPWQGELRELLETHAERRRSSAEVWREARADAAPKAADSEWTAKQVAALEAALEDAQAVATGRCRTDWVAAADRAEHREKGAALARRRDSERRASLAIRVGAVALGALVLGIGTWFLLPRTAPDGASAGVAGPATASGAPVDPALVTNLPPPVGSAALKNAALSGDASAAAEVGARYADGRGTDANQAAAMKWFAYAASQGSAPAAYRLGSIYENSKRDLPAARKLYQWAAERGNLRSMHNLGVMYSDGIDGKPDWQNAVNWFRKAADLGLRDSQFNLGVIYSRGLSGAVDRAEAWKWFSLAAAQGDTESARKREDVAAKAEPGVVDRARAAVTAFVPGKVVESANSTAVRPEWEVAGPADATPRKSASR</sequence>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <end position="96"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86515.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="208" mass="22798" checksum="480D633D9602CD8C" modified="2007-12-04" version="1">MPSHIYPDINPQAEIRDRPMLTTFTAFCGPRRIAAGLLLDVARAVRAAADTAPLLVFDDATGRVVDLDLRGTDAELAERYPAPAPEEEASPRGRGRPKLGVVAREVTLLPRHWDWLAAQPGGASVALRRLVEEARRADAPRQQARAAQEIAYRFMSAMAGDLPGFEEASRALFAGDRPRMTTEMAPWPEDIRAYTLKLAFPPAAEDEA</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMD7</accession>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169064.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0533"/>
    <dbReference type="EnsemblBacteria" id="BAF86531">
        <property type="protein sequence ID" value="BAF86531"/>
        <property type="gene ID" value="AZC_0533"/>
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    <dbReference type="KEGG" id="azc:AZC_0533"/>
    <dbReference type="eggNOG" id="COG1066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018264_0_1_5"/>
    <dbReference type="OMA" id="FELMRLA"/>
    <dbReference type="OrthoDB" id="505485at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="7">
        <location>
            <begin position="67"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="353"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="254"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="96"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="471" mass="48513" checksum="C3193E7C7115225A" modified="2007-12-04" version="1">MAKRDLSYVCQSCGAVYNRWQGKCDACGGWNTISEETNLAATVPAAQRAGRKGRAVPLETLHGEAKPAPRLVSGIGELDRVAGGGFVPGSIVLLGGDPGIGKSTLLVQASAALAKAGHRVIYVSGEEAVDQVRMRAGRLGLAQAPVALAAETNAENILATFSAGAAVQFVVIDSIQTLWSDSVESAPGTVTQVRTSAQLLVRYAKQSGAAVILVGHVTKDGQIAGPRVVEHMVDAVFSFEGDGANQFRILRAQKNRFGPTDEIGVFEMTGTGLSQVPNPSELFLSHRDAGAPGTAVFAGMEGTRPLLMEIQALVAPSSLGTPRRAVVGWDSARLAMVLAVLDARCGVRLGGHDVYLNVAGGLRISEPAADIAVAAALVSSLTGAPLPPDAVFFGEVSLTGAVRQVSQAAARLKEAAKLGFNKVVMPQLADGSASGLEVDTISSLAGLVAGIAARAPRRAAMPKPAMSDEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMG6</accession>
    <name>A8IMG6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable queuosine precursor transporter</fullName>
            <shortName evidence="1">Q precursor transporter</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0548"/>
    <dbReference type="EnsemblBacteria" id="BAF86546">
        <property type="protein sequence ID" value="BAF86546"/>
        <property type="gene ID" value="AZC_0548"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0548"/>
    <dbReference type="eggNOG" id="COG1738">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090905_1_0_5"/>
    <dbReference type="OMA" id="IWLSLFH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02088">
        <property type="entry name" value="Q_prec_transport"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR003744">
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        <source>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
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        <property type="protein sequence ID" value="BAF86562.1"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
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    </evidence>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="2" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="entry name" value="DUF429"/>
        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="BAF89733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="258" mass="27480" checksum="0CB68A4ECFFFD01B" modified="2007-12-04" version="1">MGQDGGLQPAAMVQGLDGCREGWILARWVPGGALNLLRISDLTEAFPAGTPPLVSAIDIPIGLPDRVGAGGRGPDRAVRPLLGQRQSSVFSVPSRRAVETACDISIPEEARYRAACAAALETSDPPRKISRQSFALFPKVLDVDHVLRARPGLPLTECHPEVSFWAMNGQKPLDLPKKVKGTPAAPGLDLRIRLLAAEGVPVDQLTRERARALRAGLDDLVDACACAWTAARIARGAALVFPDPPERDRYGLPVAITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A8IP18</accession>
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        <name evidence="8" type="ordered locus">AZC_3820</name>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="1 6">Required for the transposition of the insertion element.</text>
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        <text evidence="2 6">Belongs to the transposase mutator family.</text>
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    <dbReference type="EnsemblBacteria" id="BAF89818">
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        <property type="gene ID" value="AZC_3820"/>
    </dbReference>
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    <dbReference type="OMA" id="SACEIVG"/>
    <dbReference type="Proteomes" id="UP000000270">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
            <begin position="202"/>
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        </location>
    </feature>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="EMBL" id="BAF89818.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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</entry>
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    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the type III secretion exporter family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169170.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0639"/>
    <dbReference type="MEROPS" id="N06.A01"/>
    <dbReference type="EnsemblBacteria" id="BAF86637">
        <property type="protein sequence ID" value="BAF86637"/>
        <property type="gene ID" value="AZC_0639"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0639"/>
    <dbReference type="eggNOG" id="COG1377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041013_1_2_5"/>
    <dbReference type="OMA" id="YYMSHIS"/>
    <dbReference type="OrthoDB" id="1424100at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FlhB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
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        <property type="entry name" value="flhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-1005">Bacterial flagellum biogenesis</keyword>
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    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="15" id="KW-0969">Cilium</keyword>
    <keyword evidence="15" id="KW-0282">Flagellum</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="82"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="151"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="188"/>
            <end position="213"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAF86637.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="359" mass="39828" checksum="3F1187F185145D7A" modified="2007-12-04" version="1">MSDDTDKESKTEEATERKVSDALEKGNVPYSRETALFASLLGILGVLTFFVVNPVRILTVELTHFLDNPAGFTLAGSDDAIALAWGVLLLMGQVLLPAVLLLAAAGLAASLFQNTPRLVLNRIQPQFSRIDPMKGWTRIFSRDGGIEFGKSAFKLVVVAVICGVLLMSERDKVMNAMYSDPLLMPSVILSLATRLISAVCVATIVLVALDLVWSRFHWRAELRMTKQEVKEEMKQQEGDPMVKARMRSLAQQRARQRMMSSVPKATLVVANPTHYAIALYYDRQKGGAPQVVAKGTDLIALKIREIAERCSIPVIEDKPLARAMYDAVEVDQWIPPEFYKPVAKILYFIYSRGTNAAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPQ1</accession>
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        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0669</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0739"/>
    <dbReference type="EnsemblBacteria" id="BAF86737">
        <property type="protein sequence ID" value="BAF86737"/>
        <property type="gene ID" value="AZC_0739"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0739"/>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_851956_0_0_5"/>
    <dbReference type="OMA" id="HANDKAD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="364" mass="38042" checksum="40C62A735801009B" modified="2007-12-04" version="1">MTTLHLGGDRGRPVATARRPASGRVAIAMVFAGCLAVGPSPVMAQTAEAPRTATIPLLKRPDRSGFSNFIAVTASGGAGGTVLLDTGSTGLRIRQEALGPDVKLTDIPVEYSYSSGNVLHGVLGYAVVAFPGASPAVATARPIAIQVVQSITCKPEKPNCPKWKPTEVGVMGVAYSGVAAFNPLAQLPGNLSTGFIVHANDKADPNLVPHLEVGLTPENSAGYAFAAFQPAQGNQQPDGLKAWNTKSIPTCFRVDDGPAGCYATVFDTGAGLGSFETPGLPRSRLNKRVPPGRTVTTSVEGVMQLTVTAGRRPWLNRYRYEPPHGSVPGFNSGGLVFRHYRVLYDGVNGRIGFSPTTPVDAAAR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1992-08-01" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>P26481</accession>
    <accession>A8IIT1</accession>
    <name>NIFW_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Nitrogenase-stabilizing/protective protein NifW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">nifW</name>
        <name type="synonym">nifO</name>
        <name type="ordered locus">AZC_3446</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1988" name="Mol. Gen. Genet." volume="214" first="496" last="502">
            <title>Characterization of the fixABC region of Azorhizobium caulinodans ORS571 and identification of a new nitrogen fixation gene.</title>
            <authorList>
                <person name="Kaminski P.A."/>
                <person name="Norel F."/>
                <person name="Desnoues N."/>
                <person name="Kush A."/>
                <person name="Salzano G."/>
                <person name="Elmerich C."/>
            </authorList>
            <dbReference type="PubMed" id="3216855"/>
            <dbReference type="DOI" id="10.1007/BF00330486"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May protect the nitrogenase Fe-Mo protein from oxidative damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer; associates with NifD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NifW family.</text>
    </comment>
    <dbReference type="EMBL" id="M35122">
        <property type="protein sequence ID" value="AAA26188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S29387">
        <property type="entry name" value="S29387"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P26481"/>
    <dbReference type="STRING" id="438753.AZC_3446"/>
    <dbReference type="EnsemblBacteria" id="BAF89444">
        <property type="protein sequence ID" value="BAF89444"/>
        <property type="gene ID" value="AZC_3446"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3446"/>
    <dbReference type="eggNOG" id="ENOG50330W8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_145318_0_0_5"/>
    <dbReference type="OMA" id="KRMGQYL"/>
    <dbReference type="OrthoDB" id="1764222at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00529">
        <property type="entry name" value="NifW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004893">
        <property type="entry name" value="NifW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03206">
        <property type="entry name" value="NifW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005790">
        <property type="entry name" value="NifW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0535">Nitrogen fixation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000219526" description="Nitrogenase-stabilizing/protective protein NifW">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="109" mass="12150" checksum="CF623FFDB6C967D2" modified="1992-08-01" version="1">MATAGGILDQLNKASSAEDFFALLEVDYDPQVVNVVRLHILRRMGQYLVSENFEGQADDAIRARCKEVLEQAYADFLASSPLQERVFKVLKEAAQPPKPKPMVSLTVLK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1992-08-01" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>P26482</accession>
    <accession>A8IIT5</accession>
    <name>FIXA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Protein FixA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">fixA</name>
        <name type="ordered locus">AZC_3447</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1991" name="Mol. Gen. Genet." volume="225" first="514" last="520">
            <title>Nucleotide sequence of the fixABC region of Azorhizobium caulinodans ORS571: similarity of the fixB product with eukaryotic flavoproteins, characterization of fixX, and identification of nifW.</title>
            <authorList>
                <person name="Arigoni F."/>
                <person name="Kaminski P.A."/>
                <person name="Hennecke H."/>
                <person name="Elmerich C."/>
            </authorList>
            <dbReference type="PubMed" id="1850088"/>
            <dbReference type="DOI" id="10.1007/BF00261695"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1988" name="Mol. Gen. Genet." volume="214" first="496" last="502">
            <title>Characterization of the fixABC region of Azorhizobium caulinodans ORS571 and identification of a new nitrogen fixation gene.</title>
            <authorList>
                <person name="Kaminski P.A."/>
                <person name="Norel F."/>
                <person name="Desnoues N."/>
                <person name="Kush A."/>
                <person name="Salzano G."/>
                <person name="Elmerich C."/>
            </authorList>
            <dbReference type="PubMed" id="3216855"/>
            <dbReference type="DOI" id="10.1007/BF00330486"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-34</scope>
    </reference>
    <comment type="function">
        <text>May play a role in a redox process involved in nitrogen fixation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">FixA and FixB form a heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF beta-subunit/FixA family.</text>
    </comment>
    <dbReference type="EMBL" id="X55450">
        <property type="protein sequence ID" value="CAA39091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="M35122">
        <property type="protein sequence ID" value="AAA26189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S14070">
        <property type="entry name" value="S14070"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171970.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P26482"/>
    <dbReference type="SMR" id="P26482"/>
    <dbReference type="STRING" id="438753.AZC_3447"/>
    <dbReference type="EnsemblBacteria" id="BAF89445">
        <property type="protein sequence ID" value="BAF89445"/>
        <property type="gene ID" value="AZC_3447"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3447"/>
    <dbReference type="eggNOG" id="COG2086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060196_2_1_5"/>
    <dbReference type="OMA" id="ADLNEWD"/>
    <dbReference type="OrthoDB" id="1027643at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000049">
        <property type="entry name" value="ET-Flavoprotein_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01065">
        <property type="entry name" value="ETF_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0249">Electron transport</keyword>
    <keyword id="KW-0535">Nitrogen fixation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000167885" description="Protein FixA">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="281" mass="30111" checksum="25E951FDBFBA840B" modified="1992-08-01" version="1">MHIVVCIKQVPDSAQIRVHPVTNTIMRQGVPTIINPYDLFALEAALALRDQHGGEVTVLTMGPPSAEDSLRKALTFGADRAVLLTDRFFAGSDTLATTYALATAVRKIGETFGAPDIVFTGKQTIDGDTAQVGPGIAKRLGLLQLTYVAKIANVDLAGRSIQVERRSEGGVQVLQTRLPCLITMLEATNEIRRGAMADALRAARAEVVIWSAKDAGVEDISKCGLRGSPTIVKRVFAPSARAEKATMVDFSETAPADALIAEIFKRQPKLEDDLAALARGY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1997-11-01" modified="2022-05-25" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>Q43967</accession>
    <accession>A8INZ1</accession>
    <name>NOEC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Nodulation protein NoeC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">noeC</name>
        <name type="ordered locus">AZC_3810</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="1993-06" db="EMBL/GenBank/DDBJ databases">
            <authorList>
                <person name="Mergaert P."/>
                <person name="D'Haeze W."/>
                <person name="Fernandez-Lopez M."/>
                <person name="Geelen D."/>
                <person name="Goethals K."/>
                <person name="Prome J.-C."/>
                <person name="van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169678.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1147"/>
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        <property type="protein sequence ID" value="BAF87145"/>
        <property type="gene ID" value="AZC_1147"/>
    </dbReference>
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        <property type="entry name" value="ArsR-like_HTH"/>
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        <property type="entry name" value="Dimeric_a/b-barrel"/>
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        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
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        </location>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87145.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="161" mass="17985" checksum="AEA8BED7FA313BF8" modified="2007-12-04" version="1">MTVRLDAVDWKILAELQRDGRMTNVELSRRVGISAPPCLRRVRSLEEDGIIKGYRALLDEKQLGYDLMAFAMVHLISQAGSDLAAFEARIEHWPLVRASWMLSGDVDFLMLCVAPDLPTFQKFVLEITSAPNVRNVKTALTLKQSKNAPIVPLEEGSPPPE</sequence>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
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    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF87184">
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="ABC_transptr_choline_permease"/>
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    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_choXWV_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
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    </dbReference>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="110"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="113"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="305" mass="32551" checksum="B29E3F33EE417681" modified="2007-12-04" version="1">MAGVHPRPQGRCRLGERKPMYDWLVEHKIPLGRWLSAVVDFLSTHAQVVFDVISAVLAAMIGGLTAALLFIPPLLLIAACAAGAYWVHRSIGLAVFILGALLLVANLGYWDATVETLSLVLCATFVCVLIGVPVGIAAAHRPWLYTAIRPVLDLMQTIPTFVYLIPTLVLFGLGVVPGLISTVIFALPAPIRLTHLGISSVPPALVEAGEAFGATRRQLLFKVELPYALPTIMAGITQCIMLSLSMVVIAALVGSDGLGKPVVRALNTVNVAMGFEAGMAIVILAIVLDRVCKRPDRAGRRSRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRV8</accession>
    <name>A8HRV8_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding component</fullName>
        </submittedName>
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    <gene>
        <name evidence="5" type="ordered locus">AZC_4102</name>
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    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172622.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4102"/>
    <dbReference type="EnsemblBacteria" id="BAF90100">
        <property type="protein sequence ID" value="BAF90100"/>
        <property type="gene ID" value="AZC_4102"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4102"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_5"/>
    <dbReference type="OMA" id="HIMSIAE"/>
    <dbReference type="OrthoDB" id="1833499at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017780">
        <property type="entry name" value="ABC_transptr_urea_ATP-bd_UrtE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43820:SF5">
        <property type="entry name" value="PTHR43820:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03410">
        <property type="entry name" value="urea_trans_UrtE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="229" mass="24849" checksum="4728974B70A67E8A" modified="2007-12-04" version="1">MLNVENLVVSYGQSEVLHGLNFSVAPGEIVAIMGRNGMGKTTLMKSLMGVVPTRSGKVSLGEGDITAMKSHQRVAKGIAYVPQGRMIFSTMSVEENIETGLVAHGESKVPGDIYELFPVLLEMKKRRGGNLSGGQQQQLAIARALATKPKVLLLDEPTEGIQPSIIRDMARTLKRIRDERGLSIVVSEQVLSFALDIADRVLVLENGEIVHEDARADIDEAKVSKFLSV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT01</accession>
    <name>SFSA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sugar fermentation stimulation protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sfsA</name>
        <name type="ordered locus">AZC_4238</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SfsA family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172758.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HT01"/>
    <dbReference type="SMR" id="A8HT01"/>
    <dbReference type="STRING" id="438753.AZC_4238"/>
    <dbReference type="EnsemblBacteria" id="BAF90236">
        <property type="protein sequence ID" value="BAF90236"/>
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            <end position="237"/>
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    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
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    </evidence>
    <sequence length="237" mass="25481" checksum="4D30E1E06D3CBEE6" modified="2007-12-04" version="1">MRFPVPLVPARLVRRYKRFLADAVLEDGTELTAHVANSGAMLGLMAPGARVWLAPKSGKTAKLPYGWELVEADLGAGPELVGVNTMHPNVLVAEAIAAGKVPELAGYARMRREVKYGVNSRIDILLEDDDRPPCFVEVKNVHLMRAPGHAEFPDCATARGAKHLAELAAEVKAGHRAVMVYLSQIASARDIRLARDLDPAYGRAFDLARTAGVEAIGLVCRIDAQGIEVTGTIPMLG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF90242.1"/>
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    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4244"/>
    <dbReference type="EnsemblBacteria" id="BAF90242">
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        <property type="gene ID" value="AZC_4244"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4244"/>
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    <dbReference type="HOGENOM" id="CLU_888384_0_0_5"/>
    <dbReference type="OMA" id="MERHVIY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="231"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="314" mass="31265" checksum="F69C6C92D72BD362" modified="2007-12-04" version="1">MRPWSVPHAPGALTRGRRVLRANPRHLEEGDMRLAFHAALPTRILAGTALALSLAGCAGFNSQGTFGAPGTTVDGAAASAPVTASGTTVASGAGDGTEVTCPPVTVRSGASTWQVPAAGGGLRAQGTFGTLARECKVTAGQMNIRVGIEGRVILGDKGTPGAFTVPIRVALVQEGPNPVTITSKFFVVPVQILPNESQAGFAVVEEGITFPLPKGDDLERYIVYVGFDSKGEAKPAAPARPRTPRPAATSSAPSTPAASAPAASSSSSTSRPSGGASTGSAPASDTFGPPPTFSGSSSGGAVGPSPSTFGPAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT48</accession>
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        <submittedName>
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    <gene>
        <name evidence="2" type="ordered locus">AZC_4255</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="438753.AZC_4255"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90253.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="116" mass="12375" checksum="237C9FDD3EBF76D9" modified="2007-12-04" version="1">MFPRPDPVSQDEVEKLSTDQARVVQKMRRFSMVSGLVMALGIASILGVIGYRMMRGKATKAGDITATLPKGARIVSTAVADRLLVVTLDVGGTPEIRTYDLATLTPAGRLTFAVAP</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="BAF90262"/>
        <property type="gene ID" value="AZC_4264"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="8" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="454"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="525"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="22"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="555" mass="59908" checksum="EADA426B3108E7C6" modified="2007-12-04" version="1">MSVTTAGPATAHAPMTREEKKVIFASSLGTVFEWYDFYLYGSLAAIIGAQFFSAYPPATRDIFALLAFAAGFLVRPFGAIVFGRIGDLVGRKYTFLVTILIMGLSTFIVGILPNAATIGIAAPIILIVLRLLQGLALGGEYGGAATYVAEHAPHGRRGFYTSWIQTTATLGLFLSLLVILFTRSIVGEQNFAAWGWRIPFLVSIALLGISVWIRFQLNESPAFKKMKEEGTTSKAPLSEAFGQWKNLKFVLLALFGLVAGQGVVWYTGQFYALFFLQSILKVDGYTSNLLIAWSLLLGTGFFVFFGWLSDKIGRKPIILAGCLIAAASYFPLFNAITSYANPALENAIQNVKVTVVASPGECGSLFNPVGTRVYSAPCDVARDFLAKSSVKYSTETGAAGSGTVLKVNDTVVPFGPDFAKTATAALQAAGYPSAATNKDVIKMSHPFDIFQPRVAAVIGLLFVLVLFVTMVYGPIAAALVELFPTRVRYTSMSLPYHIGNGWFGGLLPATAFAMVAATGDIYYGLWYPIVIALGTFVIGLLFVPETKDRDIDDWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU16</accession>
    <name>A8HU16_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative lipopolysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rgpF</name>
        <name evidence="1" type="ordered locus">AZC_0896</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0896"/>
    <dbReference type="EnsemblBacteria" id="BAF86894">
        <property type="protein sequence ID" value="BAF86894"/>
        <property type="gene ID" value="AZC_0896"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0896"/>
    <dbReference type="eggNOG" id="COG3754">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018279_0_0_5"/>
    <dbReference type="OMA" id="HTKRSTH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007739">
        <property type="entry name" value="RgpF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032719">
        <property type="entry name" value="WbsX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41244">
        <property type="entry name" value="PTHR41244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14307">
        <property type="entry name" value="Glyco_tran_WbsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05045">
        <property type="entry name" value="RgpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="661" mass="70169" checksum="4F59B013F6C8ED57" modified="2007-12-04" version="1">MSSRRRSGKDGLDSPTGAMALRDFIRRLRYGASDACFALFPFVVERKREAAAAKEMRRRAAGKRDPAWRPPAPPVVPPKADGLGIVAFYSDLPSDTAARIEAARPQFVRHVQPVLPLLPLSASVEEEVALATAHGIDTFCFWLRADGELPAALRAILATPDLAIGIAIFFEGPLPAVRADVLDALADPRALRIDGRPMLGASGGGGDQWQAAAAARLGGPLFLVEPFAANADLSAGFSAAVQIPPRDLAPLPTPRRIESVSRAFVGPVDEFMFVADLAQHRARQATVPLFPGICAGHDSTPGQGADARIMVSPDLGDDYARWLTEVLAIARARPVAGASLVFINAWNDWLNGSHLLPDARYGHALLRATASTCAPYAGAIGARRPAAAPVTPRPVRTGSLASVVHGYYEDLLPGLIAGLDPAHLFVTTPPEKAEAVRAVLARAAPAARLRVVENRGRDVRPFLSLLPELEAEGYDLVLKVHTKRSPHQGKEGSDWLQRLSGPLLKLARSERLAPVFEAHPQMGLLGAAGHVLDGALYAGSAGNAAWMRRLAAELGTGAPLTSPYVAGTMFVARLGIFAPLRGASELLDLFDTDMGLKDGTLAHAFERFFGVLAAEAGLSVGEVAADGHVEPVAEVVNGSYAFARSTTEEELDRLRRLGAAR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVI9</accession>
    <name>RSMA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="1">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rsmA</name>
        <name evidence="1" type="synonym">ksgA</name>
        <name type="ordered locus">AZC_4320</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172840.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HVI9"/>
    <dbReference type="SMR" id="A8HVI9"/>
    <dbReference type="STRING" id="438753.AZC_4320"/>
    <dbReference type="EnsemblBacteria" id="BAF90318">
        <property type="protein sequence ID" value="BAF90318"/>
        <property type="gene ID" value="AZC_4320"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4320"/>
    <dbReference type="eggNOG" id="COG0030">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041220_0_1_5"/>
    <dbReference type="OMA" id="KEEEPYF"/>
    <dbReference type="OrthoDB" id="2030110at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Lee KB."/>
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    <name>A8HVW5_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_4366</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172886.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4366"/>
    <dbReference type="EnsemblBacteria" id="BAF90364">
        <property type="protein sequence ID" value="BAF90364"/>
        <property type="gene ID" value="AZC_4366"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4366"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_104_15_5"/>
    <dbReference type="OMA" id="AGHACTV"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="239"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="482"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="816" mass="87167" checksum="81CAA200C35B5987" modified="2007-12-04" version="1">MSQPEAAARKVHLLDRWTGEFTEQGLEAAYEQASLGASRATAFVAIFGTTLASLSFLPLDLQLIGPPDLYLFVGIRCVILVLGVCAFLVVRREDTLRGIIIATYVQQILFYFLNGIIFDHPALTRHGGLLLPIMALALPMLLPGRIWLAALVGAYGPLISLLFWGALKVPPESPADLSVILLVVGVALGVGIAARRQLNGMRRAQFLHIERERQVNVELLEAKEAAEAGARAKSQFLAVMSHEIRTPMNGILGMVRLVLDGPLEAAQRERLRVVLRAAEALQVTLDDVLDLSELEQGARLELAPLELSRVLRDAVDLMRPRADEKGLALEVVLAPDVPPCVHGDAARLRQILLNLLGNAIKFTEVGHVRLTVSRTSRPESAGRMGLRFTVADTGIGIHPQERAGLFHEFVQADASIRRRFGGSGLGLAICKRLVEAMGGEIEVESTPGVGSCFTFEVPMDVASAPVPEERFAVVSPAARPLKVLLVEDNEVNRQVALGLLERAGHACTVAETGPEAIGRVAAEIFDVVLMDIQMPGMDGLEATRRIRAAGQSLPIIALTANAMPEDVARSLAAGMNGHLAKPVRPEQLEAALARLAGRPAGAGLAEGADVLLVSRSGTSARSRLERLGLRVFPLLDLAAASTMLAHRSFALMVVAGDVDLAMARELARSSGPRLALWVEGADGPAPAPGEIRLEAAAPDAVLEAALFQQPDPANLAPVDFASLFDPGKREMLRALFVKGLSDQHAALRQCTAGDEARAIAHRISGSAANMGEFDLADRARAVMVADPESFKPAMAELLAALAARLEAGQDTMVRTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWF7</accession>
    <name>A8HWF7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4426</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4426"/>
    <dbReference type="EnsemblBacteria" id="BAF90424">
        <property type="protein sequence ID" value="BAF90424"/>
        <property type="gene ID" value="AZC_4426"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4426"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_3_2_5"/>
    <dbReference type="OMA" id="CASTAMI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="6">
        <location>
            <begin position="141"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="5">
        <location>
            <begin position="361"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="18"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="513" mass="54515" checksum="DC6785FBC74B908E" modified="2007-12-04" version="1">MLARWVSRPFPEGARTGPARREWLEEACGRDRSGNREPAARDPQGAGQGGRRRCRHRAGRRPLRPRPLLARHRQCDAGNRGPVRHRLSGRCPHPCDLPDAGRARGAGPPAARRGRSGMTGALDLAPRAEAPDRELWAQVCETARTHAAAVDQEGRYPAEAVAALKASGALGCAVPPALGGAGTGMATLARMACELGAACASTAMVFAMHHNQLACLVRHAGDNAWLRDFTAAVAAQGLLLASVTSEEGIGGRLRTSRCAVEPAGEGRFRLEKQGSTVSYGAEADAFLLTARKDAEADASDQVLVVLPRAGATVEPYRGWNALGLRGTGSGGFRISGTGDRAQVLDVPFGEIAQQTMVPNAHILWGAVWLGIATDVLARCRAFLRTRMRSGSSAAERGLPTLARMHGHLQDMEAALARAITVYDGQRADPGALEAILLKTRLSDTALTVADMGMRLCGFTAYSNEGPYSLSRHLRDLYAAPLMINNDAILADAGRLLLVNRTAFGAFDAEQDLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWH2</accession>
    <name>A8HWH2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FecI-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fecI</name>
        <name evidence="4" type="ordered locus">AZC_4431</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172950.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4431"/>
    <dbReference type="EnsemblBacteria" id="BAF90429">
        <property type="protein sequence ID" value="BAF90429"/>
        <property type="gene ID" value="AZC_4431"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4431"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_12_5_5"/>
    <dbReference type="OMA" id="LMIDQFR"/>
    <dbReference type="OrthoDB" id="1914729at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="114"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="174" mass="19710" checksum="1DF213B64EE3AA4C" modified="2007-12-04" version="1">MSLATDIPSELMLAYMRQWRELRGHLARRVGSRDLADEALQETWLRLAGMREQPVGVRDNHAFLLRIAGNIAIDLLRRERRHAMRCISDEAVLREIADLAPSPEAYALHRDELRALVMALAELPAKPRAALLMNRCDGMSHAQVAARLKVSESMVAKYLAQALRHCRDHLRAMG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY21</accession>
    <name>KDPC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Potassium-transporting ATPase KdpC subunit</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP phosphohydrolase [potassium-transporting] C chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Potassium-binding and translocating subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Potassium-translocating ATPase C chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kdpC</name>
        <name type="ordered locus">AZC_1567</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">The system is composed of three essential subunits: KdpA, KdpB and KdpC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KdpC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170095.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HY21"/>
    <dbReference type="SMR" id="A8HY21"/>
    <dbReference type="STRING" id="438753.AZC_1567"/>
    <dbReference type="EnsemblBacteria" id="BAF87565">
        <property type="protein sequence ID" value="BAF87565"/>
        <property type="gene ID" value="AZC_1567"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1567"/>
    <dbReference type="eggNOG" id="COG2156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077094_2_0_5"/>
    <dbReference type="OMA" id="KYFWPRP"/>
    <dbReference type="OrthoDB" id="1912405at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008556">
        <property type="term" value="F:P-type potassium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00276">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003820">
        <property type="entry name" value="KdpC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30042">
        <property type="entry name" value="PTHR30042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02669">
        <property type="entry name" value="KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001296">
        <property type="entry name" value="K_ATPase_KdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00681">
        <property type="entry name" value="kdpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0630">Potassium</keyword>
    <keyword id="KW-0633">Potassium transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_1000071927" description="Potassium-transporting ATPase KdpC subunit">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="11"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00276"/>
        </source>
    </evidence>
    <sequence length="188" mass="19252" checksum="DF0B68231210C044" modified="2007-12-04" version="1">MLSQIRPAITLLVAFTLLTGVAYPLAITGIGQTLFPSAANGSLVTRGGTVVGSLLIGQKTTGEGYFHPRPSAAGDAGYDAANSSGSNLAPTSQKLKARITADVAALREAGATGLIAADAVTTSGSGLDPHISPAFAYEQVERVAKARNLPETQVQTLVAGLVEGRDLGLFGEPRVNVLKLNLALDTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY52</accession>
    <name>A8HY52_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative RND efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170105.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1577"/>
    <dbReference type="EnsemblBacteria" id="BAF87575">
        <property type="protein sequence ID" value="BAF87575"/>
        <property type="gene ID" value="AZC_1577"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1577"/>
    <dbReference type="eggNOG" id="COG0841">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002755_1_2_5"/>
    <dbReference type="OMA" id="PAVDYIN"/>
    <dbReference type="OrthoDB" id="145346at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="430"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="462"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="528"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="858"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="909"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="955"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="986"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1040" mass="112281" checksum="3CA7F6455DC991C5" modified="2007-12-04" version="1">MFSELCIRRPVMTTLMMLSLIIGGLFAYRLLPVAALPRVDFPTISITATLPGASPDTMATAVATPIERQLSTISGITSLTSTSTQGSTSITIQFDLSRNIDDAALDVQSALSVAQRQLPDEMTTPPSFRKVNPADAPVILLAVSSATLPLSAVNEYADTVIGQQISQLPGVAQVQIYGTQKYAVRIRVDPAAAAARGISASDIQNAIEARASNTPIGLLSGPKQALTIDMGAAKADAGEYRKLVIAFRNGAPVRLDEIATISDGVENERVASWFNDQRAIVLAVVRQPDANTVAVVDEVRSHLGQYRSQVPASVEIDVLNDRSVSIREAVHDVQKTLFEAIVLVVLVIFLFLRNVRATIIPSLALPISIIATFGVMWALNFSINNMTLLALTLCVGFVVDDAIVVLENIYRHIEEGEKPFAAAIRGSREIGFTIISMTLSLVAVFIPVLFMGGVVGRVFREFAVTISIAILISGFVSLTLTPMLCARVLKAPDHHKTPNLFYRLTERMFDAWLAGYRHSLDFVLRHRFFMLLVTFATIGISAALYVVIPKGFFPVEDNGFITATVEAATDTSFEAMVERQKKVAAVVREDPNVAYLVSTAGATGVSRTTNTGRMFIALKPKGERKLSAFQVIQDLRRRTAQVPGVNVFYQPVQNINIGGINSKSQYQYTLQSSDTAALYAAAPALERRLAELPGLRDVTSDLQITNPQLTIDVNKDRAAAVGITEEQIRNALYTQFGTRQVATLYTSTNQYAIIAEAQSRYQREASDLSRVYLRTTSGTVVPLETVATIRRTVGPLQIAHQQQQPAVTISFNLAPGTSLGQAVEQIGQAERDAGLPASVSTGFQGTAQVFQDALGNQALLILAAVVVIYIVLGVLYESFVHPLTILSGLPSAGIGALVTLMIFDIELSVIAIIGIVMLVGIVKKNAIMMIDVALERRRQGVGALDAIREAALLRFRPIMMTTLAAIFGVLPIALGAGAGSELRQPLGVAVVGGLLLSQLLTLYITPVIYLYLDRFDGWVTRKISGDETPAVPHEQPMPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYR1</accession>
    <name>A8HYR1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 15">Aspartokinase</fullName>
            <ecNumber evidence="6 15">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ordered locus">AZC_4490</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="19">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="18 19" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="18 19" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="19">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="18 19" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
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    <comment type="pathway">
        <text evidence="2 16">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
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        <text evidence="3 16">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
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        <text evidence="4 16">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
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        <text evidence="5 15">Belongs to the aspartokinase family.</text>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173039.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4520"/>
    <dbReference type="EnsemblBacteria" id="BAF90518">
        <property type="protein sequence ID" value="BAF90518"/>
        <property type="gene ID" value="AZC_4520"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4520"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_6_5_5"/>
    <dbReference type="OMA" id="PYNLGER"/>
    <dbReference type="OrthoDB" id="1174564at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721280" evidence="1">
        <location>
            <begin position="22"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="322" mass="34303" checksum="E8B78EAC94061680" modified="2007-12-04" version="1">MRRLRLALPLLLLPLLLLALAGCDGSGPRGYSGYVEGDLLYIGPEEAGRLAALKVAEGAKVSAGTVLAGVEDDIQKADLAAAEAALAQAEARLAKAKAATQRPEEIAILSAGERRAAAALDLARIELERQKTLVPKGASSQANLDTAQHTYDQNQASLDEIRRQIDVARIASRDEDIAAAEAAVRNAKATSDAAAVRLKRRALHAPQDGTVQTLYYRVGELVPEGRPVLSLLPPGQVKVRFFIPEADLPKVRIGAPVSVSCDGCQPITADISFISDSAEYTPPVIYSREERSKLVYLIEARPRDPARARPGQPVTVTLDAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ52</accession>
    <name>A8HZ52_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4539</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173058.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4539"/>
    <dbReference type="EnsemblBacteria" id="BAF90537">
        <property type="protein sequence ID" value="BAF90537"/>
        <property type="gene ID" value="AZC_4539"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4539"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_2_5"/>
    <dbReference type="OMA" id="QANLMTI"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="254" mass="26587" checksum="E53C7BC106CB4657" modified="2007-12-04" version="1">MSKENGSVIVTGGASGIGLALVEALLTEGWRVVAADVVAENIASARESLARFGNQVRFAQIDVSDEAGVSHMVEEIDAEFGPLWGVVNSAGIGKDVPVFETSVDYFRKILDVNLIGTFLVAREGAKAMKAHGGGSIVNIASVSGLRGNLGRAAYGSSKAGVVMLTQIMAVELAPEKIRVNAIAPGPIETPLVKRMHTDEARAGWMKEVPMRRYADPSEVSGAISFLLDEQKSSFVTGQTLAVDGGFMAGGLIGL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZA8</accession>
    <name>DDL_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="2">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ddl</name>
        <name type="ordered locus">AZC_4561</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173080.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HZA8"/>
    <dbReference type="SMR" id="A8HZA8"/>
    <dbReference type="STRING" id="438753.AZC_4561"/>
    <dbReference type="EnsemblBacteria" id="BAF90559">
        <property type="protein sequence ID" value="BAF90559"/>
        <property type="gene ID" value="AZC_4561"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4561"/>
    <dbReference type="eggNOG" id="COG1181">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039268_1_1_5"/>
    <dbReference type="OMA" id="NTTPGMT"/>
    <dbReference type="OrthoDB" id="764798at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0133">Cell shape</keyword>
    <keyword id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000341057" description="D-alanine--D-alanine ligase">
        <location>
            <begin position="1"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="101"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="128"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <sequence length="306" mass="32913" checksum="635CE58584325D3E" modified="2007-12-04" version="1">MAKHVAVLMGGWSPEREVSLRSGAGCAKALEEVGYRVTRVDVDRDVAEVLARLKPDVALNLLHGCPGEDGTIQGILEILRIPYSHSGVLASALAMDKARAKVVMAAAGIPVPGGHLVTRAEAAKGHVLPPPYVLKPNTGGSSVGVFIVKEDQPHPPQELFRADWTFGESLMAEPFIKGLELTCGVMGDRALDVIEVEAVHGFYDYESKYAAGGSRHILPARVLPQIYQQVRMLALEAHRALGCRGISRADFRYDDTLPDGKGLVCLEVNTQPGMTETSLVPDMAAHAGISFGELVTWMVEDATLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZC6</accession>
    <name>A8HZC6_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">Outer membrane protein assembly factor BamD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bamD</name>
        <name evidence="3" type="ordered locus">AZC_4567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the Bam complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BamD family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173086.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4567"/>
    <dbReference type="EnsemblBacteria" id="BAF90565">
        <property type="protein sequence ID" value="BAF90565"/>
        <property type="gene ID" value="AZC_4567"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4567"/>
    <dbReference type="eggNOG" id="COG4105">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065982_1_1_5"/>
    <dbReference type="OMA" id="VERQHPY"/>
    <dbReference type="OrthoDB" id="1256747at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051205">
        <property type="term" value="P:protein insertion into membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd15830">
        <property type="entry name" value="BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00922">
        <property type="entry name" value="OM_assembly_BamD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017689">
        <property type="entry name" value="BamD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03302">
        <property type="entry name" value="OM_YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="YfiO" evidence="2">
        <location>
            <begin position="42"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="284" mass="31716" checksum="8D411856589F4E55" modified="2007-12-04" version="1">MRLFIDAAVFRAGTSRAAALLGVVLVSATLAGCANDKDVMAPDEPAEKIYNEGLTLLNKGDLDGAAKRFEDIDKTHPYSEWARKALLMDTYVYYEAGKYDDAISAGKRYLALHPGSQDAPYVSYLVASSLYDSIPDISRDQRRTRQALDALDDVIRKYPNTEYAAGAKRKVEVARDQLAGKEMLIGRYYLEQRNYTGAINRFKVVITQYQTTRQTEEALFRITEAYMALGIVNEAQTAAAVLGYNYPDSQWYKDAFKLVQSKGLLPQENKASWISQAFKKLGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0G5</accession>
    <name>A8I0G5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <location>
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    <sequence length="392" mass="40330" checksum="7A85A4FE227CBA9C" modified="2007-12-04" version="1">MRSASISNIAFGRNLIWQATAMKKPILLVAGVVTAVAGAAGFFALSPSSPHAGPIGDPREEAPLVRVMKIAPTAGLERGFTGLIEARVQSNVGFRVPGKIVERLVDVGQQVKAGQPLMRIDDTDLRLALTAKRNAVAAARAVLVQASADEKRYAALVKGGLAATPQRYEQAKAALDTAQAQLDVAEAEADVAANEATYSTLTAGADGTIVATLGEPGQVVAAGQTVIQLAQAGPREAVVALPETIRPALGSQAKARVYGSDAEPSSARLRQISDAADSQTRTYEARYVLEGPAAAAPLGTTVTITIPSGEAQPSVSVPIGAVLNDGVRTGVWVLDPTSSTVRFVPVQVKRLGNEYATVTGVALGADVVALGAHLLKDGAAVRTAKLIEGNSK</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="2">ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="2">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="2">ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="2">ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0215"/>
    <dbReference type="EnsemblBacteria" id="BAF86213">
        <property type="protein sequence ID" value="BAF86213"/>
        <property type="gene ID" value="AZC_0215"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87286">
        <property type="protein sequence ID" value="BAF87286"/>
        <property type="gene ID" value="AZC_1288"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0215"/>
    <dbReference type="KEGG" id="azc:AZC_1288"/>
    <dbReference type="eggNOG" id="COG2963">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_34_4_5"/>
    <dbReference type="OMA" id="GTVVDAC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="56" mass="6442" checksum="0A5A24B830C59D46" modified="2007-12-04" version="1">MAQKKHKPEEIVAKLRQVDVLVSQARPVAEAIRAIGVTAFTYYRWRKEFGGLRATR</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0T4</accession>
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        <submittedName>
            <fullName evidence="2">Transposase</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1294</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF87292">
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        <property type="gene ID" value="AZC_1294"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1294"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF87292.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <sequence length="90" mass="10244" checksum="75147EC77A48D421" modified="2007-12-04" version="1">MLARRRPGFSQTTSFNGKKNDGPASLEMWRFKQLERESTMLRKLVPYLPVQHLEMLQDVIRGKNVGSLRKREPVDVVCGGCPSDVCLRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
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        <lineage>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169928.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1400"/>
    <dbReference type="EnsemblBacteria" id="BAF87398">
        <property type="protein sequence ID" value="BAF87398"/>
        <property type="gene ID" value="AZC_1400"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1400"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_001681_2_2_5"/>
    <dbReference type="OMA" id="MMGVTID"/>
    <dbReference type="OrthoDB" id="117507at2"/>
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        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
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    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
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    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
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    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
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        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
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        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="32"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="736" mass="78482" checksum="EA42490D5986F91E" modified="2007-12-04" version="1">MKFETPATTNPIDRLRVVGQPLDRIDGPLKTTGTAPYAYERHDVAADPAYGYVIGAGIAKGRITRMDIEAARRAPGVIAIVTAETAGKLGKGKHNTARLLAGPHIEHYHQAVALVVAETFEQARAAAGRVRIDYAAEPGRFDLEAARWSAAKPSDEATGGAADTKVGDFARAFDAATVRLDETYSTPDETHAMMEPHASLARWEGDRLTVWTSNQMIGWAHTDLAETLGVPPEKVRVISPFIGGGFGGKLFLRADIVLAALGARAAGRPVKVALHRPLMINNTTHRPATIQRIRIGAERDGMITAIAHESWSGDLEGGGPEVAVNQTRLLYAGANRLTSMRLASLDLPEGNSMRAPGEAPGMMALEIAMDEMAEKLGIDPVDFRIRNDTQKDPEKPGRPFSARPFVECLRLGAERFGWSSRNPVPGQRREGRWLIGAGMAGAFRNNLLVKSAARVRLSADGRVTVETDMTDIGTGSYTIIAQTAAEMMGVSLEQVEVRLGDSAYPVSAGSGGQFGANNATAGVYAACVKLREAVARKLGLNAADAEFVHGTVRSGERSIPLALAASSGELTGEDGIEYGDLHKTYQQSTFGSHFVEVAVDAATGEARIRRMLAVCAAGRILNPKSARSQVIGAMTMGAGAALMEELAVDKKRGFFVNHDLAGYEVPVHADIPHQEVIFLDETDPISSPMKAKGVGELGICGVGAAVANALYNATGVRVRNYPITLDKYLDRLPDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1X0</accession>
    <name>A8I1X0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 15">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14 15">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13 15">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">bacA</name>
        <name evidence="15" type="synonym">uppP</name>
        <name evidence="16" type="ordered locus">AZC_4674</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Cell inner membrane</location>
            <topology evidence="15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="15">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the UppP family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 15"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4674"/>
    <dbReference type="EnsemblBacteria" id="BAF90672">
        <property type="protein sequence ID" value="BAF90672"/>
        <property type="gene ID" value="AZC_4674"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4674"/>
    <dbReference type="eggNOG" id="COG1968">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_060296_2_0_5"/>
    <dbReference type="OMA" id="IEGPFRD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 15" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="7 15" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6 15" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
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    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="BAF90672.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="295" mass="31616" checksum="011B16EA92354086" modified="2007-12-04" version="1">MRPPETTGCRRAGCGAFPVPFCGTKAPMTLGTLMEALVLGLLEGLTEFIPVSSTAHLLLAAHFIGFESTGKTFEVLIQLGAVLAILVVYFQRFLRVAVQLPTSPGARRFVIGIVLAFLPAAIIGVALHGFIKEVLFESPKVVCAALIFGGIVLVLLDRIPFKPRFNNAMGFPLTTALGIGFFQCLALIPGMSRSGSTIVGAMVLGADKRSAAEFSFFLALPTMLGAFVYDFWKNRNALSMDDGLLIAVGFVAAFCAALLVIRTLLDFVSRHGYAVFGWWRILIGGVSLIALYLGH</sequence>
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            <fullName evidence="3">Intracellular polyhydroxyalkanoate depolymerase</fullName>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    <feature type="region of interest" description="Disordered" evidence="1">
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="Pfam" id="PF06850"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF90689.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="451" mass="50606" checksum="0AC0FD3F50EB4EDA" modified="2007-12-04" version="1">MAAIGEFVAPVRESEEGFSLQSSPLYFMYELGYAALNPSRAMADASRLLFKNPMNPMAHTTMGKSMAAAMELYERTTRRYGKPDWGLTETTVDGVRVPVHINPVWERPFCRLLHFERAFEHPPRRPQPRLVVVAPMSGHYATLLRGTVEAFLPSHDVYVTDWADAKTVPLTEGTFGLDDYVDYLISVFHRLGGDCHVLAVCQPAVPVLMAISRMEAEDDPYVPKSMILMGGPIDTREAPTAVNALAKDKGIDFFRRNVISQVPWPHSGAMRHVYPGFLQLTGFMSMNLDRHLKAHADLFRHLVAGDGDSAEKHREFYDEYLAVMDLDARFYLETVESVFITHALPTGQMLHRSMPVRTEAVRRCALMTVEGEKDDISGVGQTRAAHKLCPHLPDEKRAHYLQPGVGHYGVFNGSRFRSEIQPRIADFILTQEHQQASGQGNVTPFPRQSGI</sequence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="261" mass="26917" checksum="93C53D59493F8DBC" modified="2007-12-04" version="1">MPNLQNKSIVITGAAGGIGAAIAKALAADGARILVADLSEEAANRVAGEITAAGGTAKAIAVDVRRRADVRAMIDAAVSAFGRLDVLFNNAGVAQTRPFLDITEDDWHFVTDVNAMGVLIGMQEAVKTFRAQGGGGKIINTASIAGKQGYEPLAHYSASKFAVVALTQAAARAFGKEGITANAFCPGVVATDMWKTIDKGFRDSGLTHKENEAFDGFAAGALLGRASRPDDLVGVARFLASSDSDFMTGQSLLVDGGMVLV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-12-16" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3Y7</accession>
    <name>NUOB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADH-quinone oxidoreductase subunit B</fullName>
            <ecNumber evidence="2">7.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NADH dehydrogenase I subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NDH-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nuoB</name>
        <name type="ordered locus">AZC_1668</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="2">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I3Y7"/>
    <dbReference type="SMR" id="A8I3Y7"/>
    <dbReference type="STRING" id="438753.AZC_1668"/>
    <dbReference type="EnsemblBacteria" id="BAF87666">
        <property type="protein sequence ID" value="BAF87666"/>
        <property type="gene ID" value="AZC_1668"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1668"/>
    <dbReference type="eggNOG" id="COG0377">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055737_7_3_5"/>
    <dbReference type="OMA" id="AGWVRKS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01356">
        <property type="entry name" value="NDH1_NuoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0874">Quinone</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0830">Ubiquinone</keyword>
    <feature type="chain" id="PRO_0000358349" description="NADH-quinone oxidoreductase subunit B">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01356"/>
        </source>
    </evidence>
    <sequence length="192" mass="21181" checksum="810798B093AB437E" modified="2007-12-04" version="1">MTPSATKPLVSEAPKGIIDPSTGRPILSDDPFYKEINAELADKGFLVTTVDDLITWARTGSLMWMTFGLACCAVEMMQVSMPRYDVERFGFAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYAVVRGCDRVVPVDIYVPGCPPTAEALLYGVLLLQRKIRRTGTIER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I472</accession>
    <name>A8I472_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1697</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1697"/>
    <dbReference type="EnsemblBacteria" id="BAF87695">
        <property type="protein sequence ID" value="BAF87695"/>
        <property type="gene ID" value="AZC_1697"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1697"/>
    <dbReference type="eggNOG" id="COG0020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038505_1_1_5"/>
    <dbReference type="OMA" id="PRTEGHK"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Akiba N."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
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    <feature type="chain" id="PRO_5002721435" evidence="1">
        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87721.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="170" mass="17997" checksum="AEACC2D453112860" modified="2007-12-04" version="1">MRVLTAVMMAVTAALSLPATVRAEGFSTHDLTPFAARVTEAIGTNCQPAADPARLTLLCPDVKGPLVDIFLRRRDSGDRIEQNMRAGKTGQAELEALCRKINDRCTVTLLDVAPAVGWIGAQPMGRQALSTAVLVRDGDELVVRALASDPQAARAAVDKALAIVRPVIGD</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF87774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012170304.1">
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    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1776"/>
    <dbReference type="EnsemblBacteria" id="BAF87774">
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Cro/C1-type_HTH"/>
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    <dbReference type="InterPro" id="IPR026281">
        <property type="entry name" value="HTH_RamB"/>
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        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018653">
        <property type="entry name" value="ScfR_C"/>
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    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
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    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="5">
        <location>
            <begin position="11"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF87817">
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        <property type="gene ID" value="AZC_1819"/>
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    <dbReference type="KEGG" id="azc:AZC_1819"/>
    <dbReference type="eggNOG" id="COG1058">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030805_0_2_5"/>
    <dbReference type="OMA" id="IGNVIVM"/>
    <dbReference type="OrthoDB" id="1834406at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="13"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="249" mass="26671" checksum="2CB57B5E50A43A05" modified="2007-12-04" version="1">MTEALGTRTITAAVLVIGDEILSGRTKDKNVGHIAERLTEIGVDLREVRVVPDVEEEIVAALNGLRHRYTYVFTTGGIGPTHDDITADSVAKAFGVSIDVDPRARAMLLEYIAEKDLNEARLRMARIPAGADLIVNEVSKAPGFKIGNVIVMAGVPRIMHAMLEAVLPTLDTGPKMLSETILANAKEGDIAGPLREIAERFPGVSIGSYPFLSETGPNTNLVVRSRDPELLAKAAREVADMVAARQPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A8I592</accession>
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            <fullName evidence="4 6">Bacterioferritin</fullName>
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        <name evidence="8" type="ordered locus">AZC_2246</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 6">Belongs to the bacterioferritin family.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170773.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2246"/>
    <dbReference type="EnsemblBacteria" id="BAF88244">
        <property type="protein sequence ID" value="BAF88244"/>
        <property type="gene ID" value="AZC_2246"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2246"/>
    <dbReference type="eggNOG" id="COG2193">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104506_2_0_5"/>
    <dbReference type="OMA" id="YQRLFHV"/>
    <dbReference type="OrthoDB" id="1890523at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00907">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002024">
        <property type="entry name" value="Bacterioferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002560">
        <property type="entry name" value="Bacterioferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00601">
        <property type="entry name" value="BACFERRITIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00754">
        <property type="entry name" value="bfr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00549">
        <property type="entry name" value="BACTERIOFERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0409">Iron storage</keyword>
    <keyword evidence="4 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="7">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR002560-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="159" mass="18420" checksum="C8E907F454781D85" modified="2007-12-04" version="1">MKGDQKVIEYLNRGLRSELTAINQYWLHYRMLDNWGYKALAKKWRAESIEEMVHADKFVDRILFLDGFPNMQVLDPLRIGQDVKEILEADLAAETEARALYQEAAAYCASVKDFPTRDLFEELMADEEGHIDFLETQLDLVAKLGLQLYAQHHIGDLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5J4</accession>
    <name>A8I5J4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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        <text evidence="1 5">Belongs to the mandelate racemase/muconate lactonizing enzyme family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170739.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2212"/>
    <dbReference type="EnsemblBacteria" id="BAF88210">
        <property type="protein sequence ID" value="BAF88210"/>
        <property type="gene ID" value="AZC_2212"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2212"/>
    <dbReference type="eggNOG" id="COG4948">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030273_4_3_5"/>
    <dbReference type="OMA" id="HEEFPVT"/>
    <dbReference type="OrthoDB" id="951991at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016855">
        <property type="term" value="F:racemase and epimerase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03319">
        <property type="entry name" value="L-Ala-DL-Glu_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034603">
        <property type="entry name" value="Dipeptide_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034593">
        <property type="entry name" value="Mandelate_racemase_DgoD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013341">
        <property type="entry name" value="Mandelate_racemase_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48080">
        <property type="entry name" value="PTHR48080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02746">
        <property type="entry name" value="MR_MLE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00010">
        <property type="entry name" value="dipeptide_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="6">
        <location>
            <begin position="130"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (R)-substrate epimerization" evidence="3">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (S)-substrate epimerization" evidence="3">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU366006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="325" mass="34303" checksum="73F9C3663093D2C2" modified="2007-12-04" version="1">MPQLSVRVERFPIAGTFTIARGSKTEAVVVVARLEADGRAGEGECVPYARYGETVEGTVKTLEDLAKAVSDGLDRTALQGAVPAGAARNALDCAFWDLEAKTHGTPVASRLGLVPPAPLVTAYTLSLDSPEAMARAARAAGRPLLKLKLGAEGDEERLAAIRAAVPQARLIVDANEGWSPDTLEARMAACARFGVELIEQPLPADNDAMLAQVKRPVTICADESVHDRHGLAALRDRYDAINIKLDKAGGLTEALALAQEGEALGFKLMVGCMLATSLAMAPALLLAQKAQVVDLDGPLLLARDRQPGIRYDGALAYPPTPDLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9Z1</accession>
    <name>A8I9Z1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2442</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170968.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2442"/>
    <dbReference type="EnsemblBacteria" id="BAF88440">
        <property type="protein sequence ID" value="BAF88440"/>
        <property type="gene ID" value="AZC_2442"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2442"/>
    <dbReference type="eggNOG" id="COG0436">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_3_5"/>
    <dbReference type="OMA" id="WMGQNTN"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901605">
        <property type="term" value="P:alpha-amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="377" mass="40332" checksum="9D0EBC8844DFEA9A" modified="2007-12-04" version="1">MSSASQRNRYFDALSSTPGLMWLGQNTNHIPAHPAVKAAMIAAIEEGAFNAYAPPLGFEALRAAIVADLGTPGAEALVTEGGVSALAMVCRAYCRPGTTFVTTDPTWKWPCLFAKQAGAEVIEIPIYDPACNYRLTPEALKAAVDERTAIIYLVDPNNPLGIRYTREEIEAFAAIARDCGAMLVHDCTYRDFADGHYPALLAAPEGAIVSLSFSKWLGLAGLRVGALVAAPAVLEACAERATSVLGASVIAQRAAEAGLKVKPEWMGEVRRIDRANKAKIKEAASAIEGFALPVYPSHGNFLVLETIGAGIRPEALVEAARREKMMIRQGTYHTARFGDRFVKVSTSVPEGWVDAFCAQLPALVATARTLNDIGPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAB0</accession>
    <name>A8IAB0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2486</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171012.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2486"/>
    <dbReference type="EnsemblBacteria" id="BAF88484">
        <property type="protein sequence ID" value="BAF88484"/>
        <property type="gene ID" value="AZC_2486"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2486"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_0_5"/>
    <dbReference type="OMA" id="ISATMRW"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="28"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="227" mass="24453" checksum="9B62FB0D31F52BFF" modified="2007-12-04" version="1">MTNGALFLETFFNPVIIARYLPAIGKGMLVTIEVAACVIVTGIALGLALAVVRSFRLKAVNAAIIVMVDILRALPPLVLVLLVYFGLPNVGLTLPSFAVLWLVLSLVLAAFAEEVFWAGIVSVRKGQWEAGRCTGLTEFQTLRYIVLPQAIRLTVPPLTNRTIAITKNTALGTVIGVPEILNQATTAQSFSGSATPLMMGAVAYLILFVPVVIAGRYIETRFAWRRA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAQ0</accession>
    <name>RS8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsH</name>
        <name type="ordered locus">AZC_2540</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171066.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAQ0"/>
    <dbReference type="SMR" id="A8IAQ0"/>
    <dbReference type="STRING" id="438753.AZC_2540"/>
    <dbReference type="EnsemblBacteria" id="BAF88538">
        <property type="protein sequence ID" value="BAF88538"/>
        <property type="gene ID" value="AZC_2540"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2540"/>
    <dbReference type="eggNOG" id="COG0096">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098428_0_0_5"/>
    <dbReference type="OMA" id="FDQGYIL"/>
    <dbReference type="OrthoDB" id="1692188at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000073189" description="30S ribosomal protein S8">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <sequence length="132" mass="14630" checksum="D2984517EE332043" modified="2007-12-04" version="1">MSINDPIGDLITRIRNAQMRRKDKTSTPGSRLRASLLDVLRDEGYIRGYTTTDHGNGRTEFEIELKYFDGQPVIREITRVSKPGRRVYASVKALPRVANGLGIAVLSTPQGVMADHDARDKNVGGEVLCTVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAY3</accession>
    <name>A8IAY3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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                <person name="Najar F.Z."/>
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                <person name="Roe B."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="6 7" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <ligand>
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            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="274" mass="29178" checksum="4D6A9BF2416C904D" modified="2007-12-04" version="1">MKMEPAAPAGVPGGAPDGRLVLSDVAFGYDGRTGRKVLEGLSLNVRDGEFVAILGPSGSGKSTLLRLVVGLERPTGGAIRLDGRPITGPRQDIGMVFQKPTLLPWRTVRDNVLLPAGFARAAGSEARTQADRLLALVGLSDVAGAYPFQLSGGMAQRVGIARMLLHDPSLLILDEPFAALDAMTREDLSLELQSIWMAGRKTALFVTHSIPEAVLLADRVVVLAGRPAKVVADVAVPLPRPRTIETLTSSEFNTIAYELRRLFRDLAGAARRAS</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <comment type="similarity">
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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        <property type="entry name" value="OppC_N"/>
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        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ABC_TM1"/>
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    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="60"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="130"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="175"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="244"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="288"/>
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    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="100"/>
            <end position="289"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="300" mass="31954" checksum="2006ACAC3B871571" modified="2007-12-04" version="1">MSQPAIALAGAKAATKGKRPATRSFWRNVGRRLLRDPVSMVCLTLLLLIVLAAIFAPYVAPHDPYRTSMARRLIAPGDARYWLGTDELGRDLLSRLIYGGRLSLFMGFAPVLIATAIGGLLGIIAGYVGGALNMLIMRVIDVFYAFPSVLLAVAISGVLGAGIGNTIFSLTLVFIPPVARVAESVATQMRNQDFVEAARATGAANWRIVLAHVVPNVTGPILSYASSLISVSIVLAAGLSFLGLGITPPEPEWGLMLNTLRQSIYVAPLNAILPGVMIFITSMCFNLMSDGLRSAMDVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBB0</accession>
    <name>A8IBB0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Galactarate dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2636</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UxaA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2636"/>
    <dbReference type="EnsemblBacteria" id="BAF88634">
        <property type="protein sequence ID" value="BAF88634"/>
        <property type="gene ID" value="AZC_2636"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2636"/>
    <dbReference type="eggNOG" id="COG2721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029189_0_0_5"/>
    <dbReference type="OMA" id="DVGWELF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008867">
        <property type="term" value="F:galactarate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046392">
        <property type="term" value="P:galactarate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11613">
        <property type="entry name" value="SAF_AH_GD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007392">
        <property type="entry name" value="Gal/Altron_deHydtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017654">
        <property type="entry name" value="GarD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044144">
        <property type="entry name" value="UxaA/GarD_SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04295">
        <property type="entry name" value="GD_AH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03248">
        <property type="entry name" value="galactar-dH20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="3">
        <location>
            <begin position="28"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="520" mass="55160" checksum="46C2E512D861EA39" modified="2007-12-04" version="1">MPDGRTQMTYQGPAGVETPRTIKVHESDNVAIVVNSFGLKPGTDLPDGTRLVEFVPQGHKVALTDIADGAPILRYGEVIGRAIGDIPRGAWVEESRVAMPVPPDLSALEKATRVPAPLPPLEGYTFEGYRNPDGSVGTKNILAISTSVQCVAGTLDFAIRRIREDLLPRYPNVDDVVAVTHAYGCGVAIGAPQSVVPIRTLQSLATHPNFGGEVMIVSLGCEKLQPERLLPEGKQGIVRLQDEAFHGFDAMIGAILEMAEARLEVLNRRKRETVPASELVVGLQCGGSDAFSGVTANPALGYAADLLVRAGATVMFSEVTEVRDAIHLLTPRAATPEVADALIREMAWYDDYLEQGGADRSANPSPGNKKGGLANVVEKALGSVAKSGSSTIAGVLAPGEKAKQKGLIFAATPASDFVCGTLQLASGMTLQVFSTGRGTPYGLSAAPVIKVATRTDLARRWHDLIDLDAGRIATGEATIEDVGWDLFRLMLDVASGKVKPWSDKWGLFNALTLFNPAPIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBF5</accession>
    <name>A8IBF5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADPH-dependent 7-cyano-7-deazaguanine reductase</fullName>
            <ecNumber evidence="1">1.7.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">NADPH-dependent nitrile oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queF</name>
        <name evidence="3" type="ordered locus">AZC_3062</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH</text>
            <dbReference type="Rhea" id="RHEA:13409"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="EC" id="1.7.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.7.1.13" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3062"/>
    <dbReference type="EnsemblBacteria" id="BAF89060">
        <property type="protein sequence ID" value="BAF89060"/>
        <property type="gene ID" value="AZC_3062"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3062"/>
    <dbReference type="eggNOG" id="COG0780">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_102489_0_1_5"/>
    <dbReference type="OMA" id="LECKEFT"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046857">
        <property type="term" value="F:oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033739">
        <property type="term" value="F:preQ1 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00818">
        <property type="entry name" value="QueF_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029500">
        <property type="entry name" value="QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016856">
        <property type="entry name" value="QueF_type1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14489">
        <property type="entry name" value="QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027377">
        <property type="entry name" value="Nitrile_oxidored_QueF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03139">
        <property type="entry name" value="QueF-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="70"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimide intermediate" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="150" mass="16867" checksum="829A41EC2C1BEFCB" modified="2007-12-04" version="1">MTEAKLQLGRETALPSSPEEAVLDRVPNPHPDTNYVARFTAPEFTSLCPVTGQPDFAHLVLDYVPDAWLVESKSLKLYLASFRNHGAFHEDCTVAIGKRLVELLKPRFFRIAGYWYPRGGIPIDVFWQTGELPRGVWLPETGVAPYRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBH1</accession>
    <name>A8IBH1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="9">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hppA</name>
        <name evidence="10" type="ordered locus">AZC_3069</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171593.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3069"/>
    <dbReference type="EnsemblBacteria" id="BAF89067">
        <property type="protein sequence ID" value="BAF89067"/>
        <property type="gene ID" value="AZC_3069"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3069"/>
    <dbReference type="eggNOG" id="COG3808">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008743_3_1_5"/>
    <dbReference type="OMA" id="MATTAMQ"/>
    <dbReference type="OrthoDB" id="98036at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="294"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="392"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="517"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="586"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="618"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="9">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="713" mass="72120" checksum="AF4B05AC1402282D" modified="2007-12-04" version="1">MLALVLIIACGLFAVGYGIWAGRAVMAADPGSPRMQEIAAAIAEGAQAYLRRQYATIGIVGVVIFLAVGVFLGWLVAIGFALGAILSGLAGFIGMNVSVRANVRTAQAATKSLAGGLDLAFKAGAVTGLLVAGLALLGVAVYFTFLTRIMGYGLTERVVVDALVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVVATMVLAIIFYSGAPGVLGNLVLYPLAIGGVCILTSIAGTFFVKLGPTSSIMGALYKGFAASAGLSVFALALVTGLLTGFGPIAGTALTGTQLFLSGIVGLAVTGAIVVITEYYTGTGYRPVVSIAQASVTGHGTNIIQGLAVSLESTALPTLVIIAGILVAYGLAGLFGIAVAATTMLALAGMVVALDAFGPVTDNAGGIAEMAGLPKEVRHSTDALDAVGNTTKAVTKGYAIGSAGLGALVLFAAYNADLRYFISQARPGSYFAGVSPNFSLENPYVVVGLLFGGLLPFLFAAMGMTAVGRAAGAIVEEVRRQFREKPGIMAGTDKPDYSRAVDMLTRAAIKEMIIPSLLPVLSPIVCYFVIYLVAGGGAAGKSAAFSAVGAMLLGVIVTGLFVAISMTSGGGAWDNAKKSFEDGFVDKDGVRHLKGSDAHKASVTGDTVGDPYKDTAGPAVNPMIKITNIVALLLLAVLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBU8</accession>
    <name>A8IBU8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3121</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171645.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3121"/>
    <dbReference type="EnsemblBacteria" id="BAF89119">
        <property type="protein sequence ID" value="BAF89119"/>
        <property type="gene ID" value="AZC_3121"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3121"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_3_5"/>
    <dbReference type="OMA" id="IVPDWHF"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="321" mass="35704" checksum="3A7BD0D96C8ADE44" modified="2007-12-04" version="1">MSRLDDVEVFLRVVDRGSFNGAAEQLGLPPTSVSRKVKALEDRLGVQLLHRTTRRVWPSEAGQAYYQKCVDAIAALDHADASIRALTQEPEGHLKVLLPHSTGILIVEPELANFRRRYPKVQLHITLDNHPLDLIEHGFDVAVRLGPVRDSSYHVRNLGSQQLIFLASPDYLDEFGRPSHPRELADHDIIAVRTSPGPLVWQLDGPSDSFEMRVSPALDTNDAIMAVRQASGACGITMLSRCMSRRRVESGELEVVLPGWQRRDPVEQVAIFPARATLDLKVRVFVDFLVDAYNRWQGEGPTRDADCARLPATPAKAKTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBV3</accession>
    <name>A8IBV3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative DEAD-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3123</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3123"/>
    <dbReference type="EnsemblBacteria" id="BAF89121">
        <property type="protein sequence ID" value="BAF89121"/>
        <property type="gene ID" value="AZC_3123"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3123"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_21_3_5"/>
    <dbReference type="OMA" id="WLLPMIC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
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        <source>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51194"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89121.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="678" mass="72178" checksum="DBE2CDEB0CD47C8A" modified="2007-12-04" version="1">MLCERVARQSDSNAQEPCAVRHGAAIFLPLETASSLRCNMRAPLRSERSALFGATMVSSIRRCVGSGSSAGCPFAACVLGRFGDRKGFRPVPFETSSPALARALAARSYTDPTPVQSAVTAPEATGRDMLVSAQTGSGKTVAYGLAVGQTLLGSDERLPAPGAPLALVIAPTRELALQVHKELAWLYAEAGGRIVACVGGMDPLREKRQLQDGAHVVVGTPGRLRDHLERGRLDMSQLAAVVLDEADEMLDLGFREDLEFILDSTPGKRQTLLFSATMPRDIAALARQYQHDALRIEVAGQKVGHADIEYRAVRVSPREIEHAVVNLLRFFEAPGAIVFCNTREAVRHLTATLQERGFSAVALSGELGQNERNLALQALRDGRARVCVATDVAARGIDLPGLGLVIHAELPHDAESLQHRSGRTGRAGRKGVSVLLVPPGRRRKADQLLAEARVVPAWSGPPTAEEVRALDQERMLSDPQLSELPAAEDANLAEALLAQYSAQELATALVRLYRARLPAPEEVTDPGEGRQKRDGRAGLGATGTGGAWFRLAVGRRKNADPKWLLPLICRRGGVTKGDIGAIRIFENETLFEIAEPLADSFIHSARASAAGDYPIEPHDGSAPERRGPPRGHGPAAGRGAAGGKGKGYGNQAGVRSWGNGPGGQKASHGARGKVRPHG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    </dbReference>
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        <property type="entry name" value="DUF992"/>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="179" mass="17972" checksum="CE07401BEDED020E" modified="2007-12-04" version="1">MTFQPVPRTASPALTATDPAAVPPVAPAEPAPVPATADKGPTRVQSGLLECRGESATAYGLGSTRTVSCEYRPASGQNQYYTGTLNRAGLDFGVSDQPSMLWMVLATSGRLGPGALAGEYVGFTSGAALGSGFSANVLVAKDANTGIALQPLSVSAENGLSISVAAASLTLQPSGPPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC78</accession>
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        <submittedName>
            <fullName evidence="5">Xenobiotic compound monooxygenase A subunit</fullName>
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    <gene>
        <name evidence="5" type="primary">dszA</name>
        <name evidence="5" type="ordered locus">AZC_3172</name>
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    <organism evidence="5 6">
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <cofactor evidence="2">
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            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
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    <dbReference type="HOGENOM" id="CLU_022256_1_2_5"/>
    <dbReference type="OMA" id="RMLGNFD"/>
    <dbReference type="OrthoDB" id="1591714at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Luciferase-like_sf"/>
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    <dbReference type="InterPro" id="IPR016215">
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    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FMN_nitrolo"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
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    <keyword evidence="5" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="4">
        <location>
            <begin position="17"/>
            <end position="385"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="3">
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            <end position="452"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
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        <ligand>
            <name>FMN</name>
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        </ligand>
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    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
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    <feature type="binding site" evidence="2">
        <location>
            <begin position="150"/>
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        </location>
        <ligand>
            <name>FMN</name>
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    <feature type="binding site" evidence="2">
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        <ligand>
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        </ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00033748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="452" mass="49716" checksum="EC28B24183B9205C" modified="2007-12-04" version="1">MTAKRQIKLGAFLMTDGHHIAAWRHPRAPANANVRIDHYLRLARIAEAAKFDALFLADSVGVRNEDLASLSHTSRAVAFEPLTLLSALSVVTQNIGLIGTASTTFNEPYHIARKFASLDLLSGGRAGWNVVTSSSEAEAYNFNLDKHVAHADRYDRAREFVSVVKGLWNTWEDDAFLRDKLGGTYFDAEKFHLLDHRGKHFRVKGPLNVARSPQGHPVVVQAGASEDGRDLAGATAEAIFAAQRTLAEAQAFYADIKGRAENYGRNPDHVKIMPGVFPVVGASEAEAREKFEELQSGIEPVVGLQLLSQVLGGFDLSGYPVDGPLPELPETNGPKSRQKLLIDAARRDNLTIRQLYLEIAGARGHWQVVGTPKQIADQLEERFTKGAADGFNVMAPHLPGGLEDFIEFVVPELRRRGLFRTEYEGTTLRENLGLPFPQHQAPRARPQVVAAE</sequence>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3216"/>
    <dbReference type="EnsemblBacteria" id="BAF89214">
        <property type="protein sequence ID" value="BAF89214"/>
        <property type="gene ID" value="AZC_3216"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3216"/>
    <dbReference type="eggNOG" id="ENOG502Z7K2">
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    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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            <begin position="734"/>
            <end position="756"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89214.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICT0</accession>
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        <name evidence="8" type="ordered locus">AZC_3249</name>
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    <organism evidence="8 9">
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        <lineage>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3249"/>
    <dbReference type="EnsemblBacteria" id="BAF89247">
        <property type="protein sequence ID" value="BAF89247"/>
        <property type="gene ID" value="AZC_3249"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3249"/>
    <dbReference type="eggNOG" id="COG0609">
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    <dbReference type="OMA" id="MFPYQIP"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
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    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
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    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <end position="128"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
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            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="416"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    </feature>
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            <begin position="599"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="632"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="651" mass="66862" checksum="EAFAF602260DC111" modified="2007-12-04" version="1">MVAGGLLLVATVLSLQKIGAALPPGLWARAFFAPDASDGQQLVIHYSLLPRILAAILAGAALALAGAVFQQVLRNPLASPTTLGVSAGAKLALALATLWAPGLFTFGREWVALAGGAIAVSLVFALSWHKGLSPLAVVLAGLVLGLYCGSVSAALILFREHYLTGLFIWGSGSLSQQGWEVVSALALQCAVTAALIALMIRPLTLLSLEEAGAASLGVSLQGTRLMALGLAVALTGFVVSGIGVIGFIGLISPALARLSGARRLRDLFLWAPTIGAGLLWTTDQLVLRTGGLTGGLIPTGAVTALFGSPLLLWLLPRLRNPTPPTRHEPIHAVARSRPQKLRLLALGLALAGALVLSLLLGRTPDGEWALARGDELSALMPWRAPRAVAALVAGAMLAVAGAILQRMTRNPMASPEVLGVGAGAALGLIVVLFTLTSAGRGVQVAAACTGAFSVLFLILVVGRRSGFTPERVLLAGIAIGALFDALVGALTASGDPRGLLLLNWMTGSTYQVDEVQAAWCVAGAVILLALAPLCGRWLDMMPLGDAPGQALGLDLGRVRLTLLALAAGLTAIATLVVGPLTFVGLMAPHLATRVGLRRALAQLAGAALVGALLMLVADWLGRMIAFPWQMPAGLIATLIGGPALMWLLARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDA7</accession>
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            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
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    <gene>
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        <name evidence="3" type="ordered locus">AZC_2902</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2902"/>
    <dbReference type="EnsemblBacteria" id="BAF88900">
        <property type="protein sequence ID" value="BAF88900"/>
        <property type="gene ID" value="AZC_2902"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2902"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_0_5"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="40"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="341" mass="37032" checksum="E73C6427790A1331" modified="2007-12-04" version="1">MMGARGRCPMRLWQAAMSGLHRTRPEPAAGGGRGKGRILIELKRLRQVVALADSGNFARAAQALHMSQPALSRSIQDLEKQLGAPLFERPPREIRPTSLGALIVEEGRELLRRAAALDAAIADHRGLSRTVVFGSGLYSNVTLVPRAIAAFAAQQPDVQVKVMAGGWRDCRDMLERGAMDFFIGERTDDEHAEAYRERPLRERQGCVVVRKGHPLCALHACTLADIAQYPFAGARLPERIARHFPRKAKLGRPDAGGKLLVPRFEAYSWTAISAIVQDSDAVAFGSASLVAESGGALVCLDVVLPWLRYVGAVVWRAERGLSSSAQSFADVAIEIDATLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDR0</accession>
    <name>A8IDR0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2979</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <sequence length="293" mass="30775" checksum="2F3F9DEBD1C8F094" modified="2007-12-04" version="1">MLMTNRLPAPWLAVALALGLGAASIGGGIYSSVQALAIARGAQAVSEGPAHAMRLLTDADRLLMDGLSELYRQDRFPAQAGARGATVRTAEAAHRFSMQLIATARLSPILADRLKDIEDDFNRAVRRACSRGGAEEGPDAGLCAPALRRVHDGLSVLRNELADMTLAHREELERDAAANTRITLIAALAATLSLVVIVLMRLSAARGSAGPSRATQAADLAAAVDHKVRSVQAETMPVPPGLPSARICAADTSRPSAGTPQRGEPQGLRAGPQRRASQGHPHLEQAWVPSPMP</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3516"/>
    <dbReference type="EnsemblBacteria" id="BAF89514">
        <property type="protein sequence ID" value="BAF89514"/>
        <property type="gene ID" value="AZC_3516"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3516"/>
    <dbReference type="eggNOG" id="COG1835">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Acyl_transf_3_dom"/>
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        <property type="entry name" value="SGNH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SGNH"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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        <location>
            <begin position="249"/>
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            <begin position="410"/>
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    <evidence type="ECO:0000256" key="1">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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        <source>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
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        <property type="entry name" value="BrnT_toxin"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="BAF89639.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="95" mass="11066" checksum="45C8C812F577C97D" modified="2007-12-04" version="1">MPMPELCFEWDATKNETNIAKHRISFPTVARAMVEKPYLSLRSDRGGEERHVSIIEIQGKLFAVIHVQRGEAIRIISARRARKDEEQQYRALFAR</sequence>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    </evidence>
    <sequence length="546" mass="61008" checksum="1C25C777E2566A5D" modified="2007-12-04" version="1">MPPRRNRMPFELPLDRRTLLKGSGTLGLSLLLGGTASAQARNETLLVVQELGPNSLDMHGVGSNQTVNGLSWNTYDRLLTYAPKTLPDGTLSYDRATLAPELAERWEEAADGMSCTFHLRKDAVFHDGTPVTAKDVKWSFDRAVSVGGFPTFQMSAGSLEKKEQFVVVDDHTFRIDYLRKDKMLLFNVAVVVPFVINSALAQKNAMADDPWAMNWLKTNTAGGGAYKVESWKPGSETILTRFDGWKSGKLPSIRRIIIRDVPSAGTRRAMLERGDADLSAGFPPKDFEQLIKEAKVKVVGVPIPNCLWYIALNTSKPPFDNVKLRQAIAWAMPYQQIQDNAFFGRAIPMYGAKSTTPAEPVWPQPFPYATDLEKAKALMVEAGFPNGLETTLSLDVGTATVGEPTALLIQENLAKIGIKAAVEKIPGANWRTTLNKKELPMVLNRFSGWLDYPEYYFYWNLHGNNSIFNISAYKNAEMDKLIDKARFSADKAEYAETVKQFIAMCMAEVPIVPLNQPMHDVAMQKSVSGYEFWFHREPDYRQFTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGH5</accession>
    <name>A8IGH5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0089</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168620.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0089"/>
    <dbReference type="EnsemblBacteria" id="BAF86087">
        <property type="protein sequence ID" value="BAF86087"/>
        <property type="gene ID" value="AZC_0089"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0089"/>
    <dbReference type="eggNOG" id="COG3786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105370_0_0_5"/>
    <dbReference type="OMA" id="PDDGWCD"/>
    <dbReference type="OrthoDB" id="1915613at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="33"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="179" mass="20017" checksum="26C699442729A1B0" modified="2007-12-04" version="1">MTRQLPVGIATITVRRRPGCRHQGVLTVAGRAIPVALGRSGIGCDKREGDGRTPAGVWHPVRVLYRADRVTRPATSLPVAAIRPDDGWCDAPEDRRYNRPVELPFPASHERLWRDDRLYDLLLVIDHNTRPRVKGRGSAVFIHLARPGYRPTEGCVALKPADLSRLLTRLDARTRIIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGK8</accession>
    <name>A8IGK8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA binding S1 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0102</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168633.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0102"/>
    <dbReference type="EnsemblBacteria" id="BAF86100">
        <property type="protein sequence ID" value="BAF86100"/>
        <property type="gene ID" value="AZC_0102"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0102"/>
    <dbReference type="eggNOG" id="COG2183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009833_0_2_5"/>
    <dbReference type="OMA" id="RWAWRTR"/>
    <dbReference type="OrthoDB" id="120764at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="3">
        <location>
            <begin position="652"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="722"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="781" mass="83518" checksum="25F265A23A0EB3F5" modified="2007-12-04" version="1">MAAPSADIARIIAGEIAAKPAQVVAAVGLLDEGATVPFIARYRKEVTGGLDDTQLRTLEERLSYLRELEARRASVLQSIETQGKLTDELAAKIRAAGTKAELEDLYLPYKPKRRTKAEIARERGLGALAEAILADRTKEPSVLAQGFLKEEVPDVKTALDGARDILVEMFAENADLVGRLRGHLQANARIVSKVVAGKEEAGAKFRDYFDHWEKWATVPSHRALAMLRGRNEEFLTLDIEVDWDDASPVKPVERMIAASVNVGPVGGGPGDAFLRDVARWAWRVKLSLHLSIDLMTAMTEKAEEEAIRVFARNLKDLLLAAPAGSRTTIGLDPGIRTGVKVAVVDGTGKLLGTSTLYPFQPRNDIAGASAELARLIVKHQVELIAIGNGTASRETEKFAADVIAKLPGTKPRTVVVSEAGASVYSASALAAAEMPDLDVSLRGAVSIARRLQDPLAELVKIEPKSIGVGQYQHDVDQNRLAKSLDAVVEDAVNAVGVDLNTASAPLLSRISGLGASLAEAIVAHRNQVGAFANRKELLKVARLGPRTFELCAGFLRITGGTEPLDASSVHPEAYGLAKKIISACGRDIRSLMGDSATLKRLDPAVFVDERFGLPTVRDILSELEKPARDPRPEFRTATFMEGVNTMSDLKPGMLLEGTVTNVAAFGAFVDIGVHQDGLVHVSALADRFVKDPHEVVKAGDIVKVRVVEVDVARKRIALSMRKDGGEVRAARPQGGPPQGRPLPGGKFTAGPKPGNDGRRNAPPADGALAAALAEAMKRKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGW1</accession>
    <name>A8IGW1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA polymerase III subunit gamma/tau</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dnaX</name>
        <name evidence="7" type="ordered locus">AZC_0142</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DnaX/STICHEL family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0142"/>
    <dbReference type="EnsemblBacteria" id="BAF86140">
        <property type="protein sequence ID" value="BAF86140"/>
        <property type="gene ID" value="AZC_0142"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0142"/>
    <dbReference type="eggNOG" id="COG2812">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_006229_0_7_5"/>
    <dbReference type="OMA" id="HVDVMEM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18137">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022754">
        <property type="entry name" value="DNA_pol_III_gamma-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022107">
        <property type="entry name" value="DNA_pol_III_gamma/tau_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012763">
        <property type="entry name" value="DNA_pol_III_sug/sutau_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045085">
        <property type="entry name" value="HLD_clamp_pol_III_gamma_tau"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12169">
        <property type="entry name" value="DNA_pol3_gamma3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12362">
        <property type="entry name" value="DUF3646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02397">
        <property type="entry name" value="dnaX_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="62"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="408"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="613" mass="65601" checksum="DFB7B65F1FA06FBB" modified="2007-12-04" version="1">MSADTPEDMPAFDLPAATPAPAPQAAPYRVLARKYRPQNFDDLIGQEAMVRTLSNAFASGRIAQAYILTGVRGVGKTTTARILARALNYEPMDGSPGGPSLDLSVFGKHCKDIIESRHVDVMEMDAASNTSINDIREIIEGSRYRPVMARYKVYIIDEVHMLSTAAFNGLLKTLEEPPEHVKFIFATTEIRKVPVTVLSRCQRFDLRRVEAGVLAAHLSRICAKENVSVDAEALSIVARAAEGSVRDSLSLLDQAIAHGGGAVTGEEVRRLLGLADKARVIDLFDALMKGDMPRALAEFRDQYDSGADPAVILTDLAEFTHLVTRLKIVPDSASDASLVEAERIRGVEMAEALSMRVLSRTWQMLTKGIAEVQQAAKPAQAAEMVLVRLAYAADLPTPDEALRKLKDMPAPEASAPPSPPSGGGGGMGGGAMTAMAAGGGARLSVAARSEPAPQRVAAEPVAVAGPQLSSLADVVALATQKRDLMLKHAVESHARLVHFEEGRIEISMAPGGDPNLVQDLSRKLAEWTGRRWLVSLSSKQGEATIAEIARAAREEREDGIRAEPLVAAVLSQFPGAQIVDVRIKEEVPEATLAPVEEVDSGPDADEDGLSPFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH44</accession>
    <name>A8IH44_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TRAP dicarboxylate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dctP</name>
        <name evidence="4" type="ordered locus">AZC_0171</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 7 family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <location>
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    <feature type="chain" id="PRO_5002723628" evidence="3">
        <location>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
    <evidence type="ECO:0000313" key="5">
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    <sequence length="329" mass="35138" checksum="6CEF2F817F4F9E80" modified="2007-12-04" version="1">MTRLRTIAAALIAGGLAALSAGTASAQTKWNLPTGYPQDNFHTENIAQFAKEVDSASGGKLLITVHPGASLFKVPEIKRAVMTGQAQAGEVLMSVHENEDPIFGIDTVPFLATSYPAAKKLWDASRPAVEKKLDSQGLKLLFAVPWPPQGLFSKTAVTKVEDLKGVKWRAYNPGTSRIAALVGAQPVTVQQAELAQALATGVVAALITSGATGYDVKIWESVPYFYDIQAWLPKNMVFVNKAAFEALDKPTQEAVLKAAAAAEARGWKTSEEKSTWFLKELAAKGMTVAPPSPELKAGFEKVGKDLTADWEKKAGENGVAIIKAYEAAK</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
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        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
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        <property type="protein sequence ID" value="BAF89269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_3271"/>
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        <property type="project" value="UniProt"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="ADH-like_C"/>
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        <property type="entry name" value="ADH_N"/>
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        <property type="entry name" value="ADH_Zn_CS"/>
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        <property type="entry name" value="GroES-like_sf"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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        <property type="entry name" value="PKS_ER"/>
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        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
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    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="10"/>
            <end position="336"/>
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    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
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    <evidence type="ECO:0000259" key="3">
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    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89269.1"/>
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    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <sequence length="338" mass="35809" checksum="34999C0421148C2A" modified="2007-12-04" version="1">MFGTMLYGKGDVRCEAVPEPEILKPTDAIIKLSASCICGSDLWPYRGLNDVTAPMAMGHEYCGIVTQVGSAVRTVRPGQFVVGSFCLSDNTCPHCRFGFQSSCEQREFMSGAQAPYARVPLADGTLVATDTVPDDDLLPSLLATSDVLGTGWYAADAARVQPGSTVVVVGDGAVGLMGVLAARQMEAGRIIAMSRHKSRQDLALEFGATDIVSARGAEGIAEVKRLTGNVGADSVLECVGTGESMAQAIACARPGAMIGYVGVPHGVELNGEQLFFSQTGMLGGPAPVRRFLPHLMDLVLSRKINPGKVFDLTLPLEDVAEGYRAMDERRAIKTLLRV</sequence>
</entry>
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    <gene>
        <name evidence="3" type="ordered locus">AZC_3275</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3275"/>
    <dbReference type="EnsemblBacteria" id="BAF89273">
        <property type="protein sequence ID" value="BAF89273"/>
        <property type="gene ID" value="AZC_3275"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3275"/>
    <dbReference type="eggNOG" id="COG2080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="1819473at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
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        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="155" mass="16330" checksum="86836EF81A526C47" modified="2007-12-04" version="1">MAKLNVNGRDFEIDVEEDTPLLWALRDHVGLTGTKYGCGVAQCGACTVHLDGVATRSCSVPVSAVEPGQKIVTIEGLGAEKPHPVQLAWAELDVAQCGYCQVGMIMAVSALLAQNPSPSDEDIRSEITNICRCGTYGRVLAGTKLAAARMASNRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHU8</accession>
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    <gene>
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        <name evidence="2" type="ordered locus">AZC_3324</name>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89322.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF89322">
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        <property type="gene ID" value="AZC_3324"/>
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    <dbReference type="KEGG" id="azc:AZC_3324"/>
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    <dbReference type="Proteomes" id="UP000000270">
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    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="Methyltransf_11"/>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="70"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="274" mass="29903" checksum="0188CC0D32EFAE31" modified="2007-12-04" version="1">MNVHAPETRAFDPVSAQFDWLLDHIGQNRFLPQPPADSIFVGDGDFRAIGAEFLRHFVTLGGLRRSHRVLDVGSGIGRMAVPLTQFLHPERGSYEGFDPVLDGVAWCATTITPAYPKFRFQKLDIAHALYNPGGVVAGKDLVLPYGDANFDFAIMVSVATHLPADELAAYIREIARVLGPNGKLFLTAFVLDEVARAGDGRDARLGFVRDGEGPCWFANAEAPLAAVGFDDGFIDGLLREVGFDIGLKSLGHWRGIPADHYQDIFVARKRGGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8II05</accession>
    <name>A8II05_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">ABC transporter membrane spanning protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171868.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3345"/>
    <dbReference type="EnsemblBacteria" id="BAF89343">
        <property type="protein sequence ID" value="BAF89343"/>
        <property type="gene ID" value="AZC_3345"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3345"/>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_016047_18_5_5"/>
    <dbReference type="OMA" id="ADGMLTY"/>
    <dbReference type="OrthoDB" id="1488093at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="77"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="300" mass="32397" checksum="48465EDF2C82F705" modified="2007-12-04" version="1">MSRPVSLDAPRISLSQRLAARGIDGLTLLVLPAALFILGLFVYPFLYGLWLSFQPKVGGTLANYVKFFSDPFLYGTIATTLWLALPVTILNIVLAVPIALRVRHLRRQRLLTTILVIPITLGTVLVAEGLLNYLGPQGWFNRTLITLGLISKPLALLHNYWGVFISLLLTGFPFTFLLTLSYLSGLDPALEQAAATLGAGSWQRFRHIILPLLLAGLAITFCLSFVQAFSVFPSAVLLGAPAGPTRVISIAAYQAAFEDYDYSMASAIAMIMAVVQLAIVAALLFARGLIYRGATSGGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8II17</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3350</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF89419">
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89419.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="120" mass="13832" checksum="18A6C7164EDBE9B1" modified="2007-12-04" version="1">MMRSAAMTSANLRLSPHPNDLDRKRIERGLENRKRYRYVSPLVKATAGGYHISSPCCSRNIDPEGGIVDVALLIHEVDTGRWQLYAREHAARRWGLHSIHEKLSDALEEINLDPERIFWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIS0</accession>
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        <name evidence="3" type="ordered locus">AZC_3442</name>
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    <organism evidence="3 4">
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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    <evidence type="ECO:0000256" key="1">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <property type="protein sequence ID" value="BAF86205"/>
        <property type="gene ID" value="AZC_0207"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    </feature>
    <evidence type="ECO:0000259" key="1">
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="2">Belongs to the CpxP/Spy family.</text>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="177" mass="18855" checksum="16C08470BA05D49A" modified="2007-12-04" version="1">MPRLVTHLISATVLGAILASGPAAFAQPAAPQTPAAAPAPAPAIIVTEAYSEADARAVLNARLAALKAVIELTPEQEKLWPPLEAAIRDISKNAVARRKQMETAQPPKDFLGVLDQIGTAEEIRGRELKRFVEAARPFVASLTEAQKRRIPPFLGLQDTGGAHQPAGTLWLFEEEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJI0</accession>
    <name>A8IJI0_AZOC5</name>
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        <submittedName>
            <fullName evidence="4">Putative diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0308</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0308"/>
    <dbReference type="EnsemblBacteria" id="BAF86306">
        <property type="protein sequence ID" value="BAF86306"/>
        <property type="gene ID" value="AZC_0308"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0308"/>
    <dbReference type="eggNOG" id="COG2199">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2200">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_70_50_5"/>
    <dbReference type="OMA" id="VNRAHET"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd01948">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001633">
        <property type="entry name" value="EAL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035919">
        <property type="entry name" value="EAL_sf"/>
    </dbReference>
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        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00563">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00052">
        <property type="entry name" value="EAL"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141868">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="179"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="EAL" evidence="2">
        <location>
            <begin position="323"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="566" mass="61642" checksum="3D1F951FE33DEC28" modified="2007-12-04" version="1">MAGRNPSSPVTPAPPAGEPKTVLDTPEQTLQALQTLQCLVYRWDLTANTVHWSANSGEALGPALLEQLGRGTTFRAFLGCTDESTDYHRFARALPLASMPYEALVRPAIDGTPAAFRVHDQGRWRAGSDGQPEQAVGTLEILPLLAPVIPGGTADPLTGALTRRHLTEALGTLPFGPQARWALLLVGLDDLGRINDRFGFETADRLLVALAGRLRQQLSSADLLLRFSGNKFAILLTETSVEALGAFGERLISEIREARLSAGEGQLPVSVTIGAILPPHQGEAPDAIIARLQEAHEMAKRRGRGRFFLDLQGTRNEGRRRANLQMADEIVQAIDRNDVTVAYQPVVRATTRTLVFCEALARIAHDRYSRQYSGHRLVAAADSLGLMGHLDRSMLKQVAADMRRDPTLHVSINVSASSIMDEAWIALYRREVDTDIGRRLIVELTESVAVDHLSAARNFIAQVRPSGARIAIDDFGAGATSFRNLRKLGVDLVKIDGGYIINMAKSPDDQAFVRALLTLSRQLGIETVAEWVQNEIVAAQLLEWGCDYFQGSLSGLARPLATEHGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJJ2</accession>
    <name>A8IJJ2_AZOC5</name>
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        <domain>
            <recommendedName>
                <fullName evidence="7">Glutamate N-acetyltransferase</fullName>
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            <alternativeName>
                <fullName evidence="7">Ornithine acetyltransferase</fullName>
                <shortName evidence="7">OATase</shortName>
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            <alternativeName>
                <fullName evidence="7">Ornithine transacetylase</fullName>
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        <domain>
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                <fullName evidence="7">Amino-acid acetyltransferase</fullName>
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            <alternativeName>
                <fullName evidence="7">N-acetylglutamate synthase</fullName>
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        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ alpha chain</fullName>
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        <component>
            <recommendedName>
                <fullName evidence="7">Arginine biosynthesis bifunctional protein ArgJ beta chain</fullName>
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        </component>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">argJ</name>
        <name evidence="8" type="ordered locus">AZC_0314</name>
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    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:15349"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57805"/>
            <dbReference type="EC" id="2.3.1.35"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24292"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Heterotetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the ArgJ family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.35" evidence="7"/>
    <dbReference type="EC" id="2.3.1.1" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168845.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0314"/>
    <dbReference type="MEROPS" id="T05.001"/>
    <dbReference type="EnsemblBacteria" id="BAF86312">
        <property type="protein sequence ID" value="BAF86312"/>
        <property type="gene ID" value="AZC_0314"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0314"/>
    <dbReference type="eggNOG" id="COG1364">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027172_1_0_5"/>
    <dbReference type="OMA" id="DYVHENS"/>
    <dbReference type="OrthoDB" id="1083409at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00106"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004042">
        <property type="term" value="F:acetyl-CoA:L-glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004358">
        <property type="term" value="F:glutamate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103045">
        <property type="term" value="F:methione N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02152">
        <property type="entry name" value="OAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01106">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002813">
        <property type="entry name" value="Arg_biosynth_ArgJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042195">
        <property type="entry name" value="ArgJ_beta_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23100">
        <property type="entry name" value="PTHR23100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01960">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00120">
        <property type="entry name" value="ArgJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_5023343071" description="Arginine biosynthesis bifunctional protein ArgJ alpha chain" evidence="7">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023343070" description="Arginine biosynthesis bifunctional protein ArgJ beta chain" evidence="7">
        <location>
            <begin position="195"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="408"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="site" description="Involved in the stabilization of negative charge on the oxyanion by the formation of the oxyanion hole" evidence="7">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="7">
        <location>
            <begin position="194"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="413" mass="42830" checksum="AC0F66A75242BB53" modified="2007-12-04" version="1">MSASISPLAPSALPEVPPVPGVRFATAEAGIRYQGRTDALLVAFDKGTAVAGVTTRSLCPSAPVEWCREALKKGKARGLVVNSGNANAFTGLKGRESTALTARIAADALGCKPTEIFLASTGVIGEPLDATKFQGVMGDMAGRLAAGPWEGPARAIMTTDTFPKLATAQVPFGNTTVTIAGIAKGAGMIAPDMATMLSFVFTDAPIAAPVLQKLLSKLVVNSFNAVTVDGDTSTSDTLLLFATGAAKEVGAPAVKDSADPVLRPFRKALKAVLNDLAEQVARDGEGARKLIRVHVSGAVSKSSARRIAFSIANSPLVKTAVAGEDANWGRVVMAVGKAGEPADRDRLAISFGDIRVAAEGARDPSYDEQVVSDYMKGDVIDIRVDLGLGKGADRVLTCDLTKEYVAINGDYRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJL1</accession>
    <name>A8IJL1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TRAP transporter solute receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168854.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0323"/>
    <dbReference type="EnsemblBacteria" id="BAF86321">
        <property type="protein sequence ID" value="BAF86321"/>
        <property type="gene ID" value="AZC_0323"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0323"/>
    <dbReference type="eggNOG" id="COG2358">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033215_4_1_5"/>
    <dbReference type="OMA" id="TTGVYFP"/>
    <dbReference type="OrthoDB" id="991310at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011852">
        <property type="entry name" value="TRAP_TAXI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42941">
        <property type="entry name" value="PTHR42941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16868">
        <property type="entry name" value="NMT1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02122">
        <property type="entry name" value="TRAP_TAXI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723665" evidence="1">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="313" mass="32908" checksum="75F790F032A8A0D5" modified="2007-12-04" version="1">MRKLALAALAAVFALSPLAARADFINILTGGTSGVYYPLGVAISKIVSDKVPGARPSVQATKASVENLILIQQGKGEIGFTLADSLADGWAGKEDAGFKTPLKKVRALAAIYPNYIQIVASKDSGIKSIADLKGKRLSVGAPKSGTELNARAILNAAGLKYEDLGKVEYLPFAESVELMKNRQLDATLQSAGLGVASIKDLATSVEINVVEIPASVVEKVGTPYLKASIPAGTYTGQDKDVPTAAVPNFLVVREDMKEGDVYAITKAIFENLPELQAAHVAAKSISLKDAMKGSPVPFHPGAEKYFKEQGVTP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJU8</accession>
    <name>BIOB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Biotin synthase</fullName>
            <ecNumber evidence="1">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bioB</name>
        <name type="ordered locus">AZC_0361</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="1">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168892.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IJU8"/>
    <dbReference type="SMR" id="A8IJU8"/>
    <dbReference type="STRING" id="438753.AZC_0361"/>
    <dbReference type="EnsemblBacteria" id="BAF86359">
        <property type="protein sequence ID" value="BAF86359"/>
        <property type="gene ID" value="AZC_0361"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0361"/>
    <dbReference type="eggNOG" id="COG0502">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033172_1_2_5"/>
    <dbReference type="OMA" id="AMGVHRY"/>
    <dbReference type="OrthoDB" id="940969at2"/>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0001">2Fe-2S</keyword>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0093">Biotin biosynthesis</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000381211" description="Biotin synthase">
        <location>
            <begin position="1"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="43"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="325" mass="34656" checksum="62ABD145AEB3B8C6" modified="2007-12-04" version="1">MSAAIAATARPAAEMRTRALYDLPLPELMFRAQAVHRAHFDACSVETAQLLSIKTGGCPEDCGYCSQSAHHDTGVAATRLMDVEAVLAEARKAKAAGAARFCMGAAWRAPKDRDMDAVCAMISGVRALGLETCVTLGMLTPAQVDRLSAAGLDYYNHNVDTSPAYYPRITSTRTLDDRLETLGHVRAGGIKVCCGGIVGMGETIEDRLAMLELLAGLDPHPESVPLNMWTPIDGTPVKAFEEKVDPIAFVRLVAVARLLMPRSVVRLSAGRHTLSDEAQALCFLAGANSIFVGDTLLTTPNMEESRDAVLLARLGLRPAPAQPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJW9</accession>
    <name>A8IJW9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168901.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0370"/>
    <dbReference type="EnsemblBacteria" id="BAF86368">
        <property type="protein sequence ID" value="BAF86368"/>
        <property type="gene ID" value="AZC_0370"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0370"/>
    <dbReference type="eggNOG" id="COG0400">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049413_5_2_5"/>
    <dbReference type="OMA" id="GRQWYGL"/>
    <dbReference type="OrthoDB" id="1195966at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="219" mass="22680" checksum="B3F836254D9F4EA9" modified="2007-12-04" version="1">MSLTEGPRLAPSAGGPADSLVVLVHGYGADGRDLIDLGAAWAEILPHTAFVAPHAPHPCDQMPVGRQWFPLSLADPHAIARDTLSALPAFARLLDEERTRLDLPWSRVALFGFSQGAMMALSFAVTAPEPIAAVVGASGFLPPLLPPGLAPSRPPVLLMHGGRDEVVPVYALTATAAALSAAGVRAETHLTQSLGHGIDEEGVERAGLFLAAHLAPPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK73</accession>
    <name>A8IK73_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3869</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172389.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3869"/>
    <dbReference type="EnsemblBacteria" id="BAF89867">
        <property type="protein sequence ID" value="BAF89867"/>
        <property type="gene ID" value="AZC_3869"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3869"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_3_5"/>
    <dbReference type="OMA" id="FHAVMTT"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721729" evidence="2">
        <location>
            <begin position="22"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="HTH lysR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="298" mass="32666" checksum="B981C280428340B2" modified="2007-12-04" version="1">MRFSHVAAFRAVMLSGSMTMAAHELNTSQPNVSRLITQLEKDTGLKLFSRMAGRLQATPEAHAFYRDVERAYVGLADLEQSAQTIRKLGTGHLRVGAVPSMGLTVLPGIMRDFAAVHPAVRISVHFGDSVTVAQWTASRFCDIGITSYISDAIGVEADLALKMDGVCIVPPKHRLARRRTPLQPKDLAGEPFISLSHGDRRHIDSVFTRGGEDKRDLAHECQYAAVICSMVGNGMGLSIVNPIVADFYKHTGISVHEFEPSIQFMSYILTPLRYAKSELTSEFSAMIKNHISDALGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKA0</accession>
    <name>A8IKA0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2285 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3879</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3879"/>
    <dbReference type="EnsemblBacteria" id="BAF89877">
        <property type="protein sequence ID" value="BAF89877"/>
        <property type="gene ID" value="AZC_3879"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3879"/>
    <dbReference type="eggNOG" id="COG5419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111973_3_0_5"/>
    <dbReference type="OMA" id="RDWISHE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018754">
        <property type="entry name" value="DUF2285"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10074">
        <property type="entry name" value="DUF2285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2285" evidence="1">
        <location>
            <begin position="59"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="167" mass="18550" checksum="F193B7E7BE7015CC" modified="2007-12-04" version="1">MIVGSPPAFADGVRLREVDGISTLQLSPEGAHASIGEGRHQSQILFLPVRHRDALMAAVIPMDADLMGRVEALKRFWRTVEGRLPPPDMRMTPQQRRRLRSMMLAADGRANHASYRDIAVALFGAMRATSEPWKTSSLRDRVIGLVKGGHALIGGGYLKLLRHRRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKI8</accession>
    <name>A8IKI8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative diguanylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3914</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="17"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="170"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89912.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="306" mass="33363" checksum="D9074C8A9784594C" modified="2007-12-04" version="1">MIASPPDLIAKLALYSIDAIADMIVWADREGRYVCVNKAAQRLLGYTEEEFQGRRVCDVDPLFDEARWREHWAELERLGSVTLETVNTTKDGVDVPVEVTANLVSVDGRLFNCSIVRDITERRRNEAERRALNERIYQLSITDGLTGISNRRRFDEALASLVAQHARSGKPLSVILIDIDHFKAFNDHYGHLSGDDCLRQVAAVIASLMRGESDLAARFGGEEFACVLPGLDLAGAASVAERLRSGIAGLGIPHAKADGGHVTASIGAVCCERPMAQTSHGLLATADALLYRAKGEGRNRVAVARL</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKU3</accession>
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            <fullName evidence="8">Signal recognition particle protein</fullName>
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        <alternativeName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="8">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF89949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF89949">
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        <property type="gene ID" value="AZC_3951"/>
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    <dbReference type="OMA" id="DTAGRHK"/>
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    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
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        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:GTPase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SRP54"/>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
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        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
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        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
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        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
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    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
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    </dbReference>
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        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="10">
        <location>
            <begin position="269"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="467"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="248"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF89949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="511" mass="53902" checksum="7FEDE7C425B8C38C" modified="2007-12-04" version="1">MFDSLSDRLGGILDKLKRRGALTEADVGEAMREVRRALIEADVALDVVRSFTDKVRQRAVGVEVIKSVTPGQMVVKIVHDVLVETLGSDADPIDLNAPAPVPILMVGLQGSGKTTTTAKIAKRLTERGNRRVLMASLDTRRPAAMEQLATLGTQVEVNTLPIVPGQSAVQIAKRAMDAARFGNYDVVILDTAGRVTLDEALMAEVAEVKAITNPHEVLLVADSLTGQDAVNTAKAFDSRVSITGIVLTRADGDGRGGAALSMRAVTGKPIKLLGTGEKMDGLEDFDPQRVAGRILGMGDVVALVEKAAENLDIEKAKATAERMRKGVFDLEDLRDQLFQMQKMGGMGGLMGMLPGIAKVKNQIAAANLDDKVFKRQVAIINSMTRQERRNPKVLDASRKKRIASGSGTKVEEINRLIKMHRQMADVMKAMGGAAGKRGPLAGLASMMGMGAGGPSPEMLQQMAEKMPGGLPGGGGLPPTFPGGLPGLGKGLPPGLPKGFPGLPGLGGPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL39</accession>
    <name>A8IL39_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Two-component response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_3985</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172505.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3985"/>
    <dbReference type="EnsemblBacteria" id="BAF89983">
        <property type="protein sequence ID" value="BAF89983"/>
        <property type="gene ID" value="AZC_3985"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3985"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_1_5"/>
    <dbReference type="OMA" id="LMLTARC"/>
    <dbReference type="OrthoDB" id="1020672at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="125"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="125"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="224" mass="25136" checksum="150230DF03F6C422" modified="2007-12-04" version="1">MRLLVIEDDPELGSWLRTTLEDAFGGADLVTSLDEAQAAVKVREFDLIVMDRRLPDGDSIELIGAFQRLRPRPSLLVLTALDDPNHIAKALDAGADDYLAKPFEPVELIARVRAVMRRAQLDQSDGVVTVANLRFCTAARTAYIEDTSLILPRRELALLEALIRRVGQVVLRETLENAAYGFDDEIQSNAIDAHLSRLRKRLREHNCQAQIRPLRGLGYMLSEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILE6</accession>
    <name>A8ILE6_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">TRAP-type mannitol/chloroaromatic compound transport permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_4023</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172543.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4023"/>
    <dbReference type="EnsemblBacteria" id="BAF90021">
        <property type="protein sequence ID" value="BAF90021"/>
        <property type="gene ID" value="AZC_4023"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4023"/>
    <dbReference type="eggNOG" id="COG4664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_552000_0_0_5"/>
    <dbReference type="OMA" id="RTIAPGM"/>
    <dbReference type="OrthoDB" id="2030181at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010656">
        <property type="entry name" value="DctM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004681">
        <property type="entry name" value="TRAP_DctM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33362">
        <property type="entry name" value="PTHR33362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06808">
        <property type="entry name" value="DctM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="337"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="4">
        <location>
            <begin position="18"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="480" mass="48760" checksum="0A7471FF6DDF0F6E" modified="2007-12-04" version="1">MSAFGLVLLLMIGVGSVFTGLPNVVVLLATAVFGVLVGLFTGVITPNLLPALPTRIIDLMSSDLLQALPLFVFLGTLLNRLPVASALFRTGLALLPRSPASAPVTGIGIGVLLGPMNGSVGASAMALTRTIAPGMAANRVPLATIQAVTAVAATLGVVVPPSLVLILLGDAMLNAHTVALNASGRIAQVVNTQDVFQGALLPAGLFVAGSILVTVLTQRRQSAAPAERPPLSLPDALITLLALPFVGGLLVSVALGYVYPVEAAACGAVVLFLAGLLSGHVSRATIGPLLDETLRMTGALFALLAAATTLTLVFRLFGTDKLVAAAIQSVPGGPAAATVAALLVVAASALVLDAFEIIFVIVPLIAPPLLVRADDAAWVAVLILLTLQMSFLLPPLGYALVVTRDRLKGDAPMSAMLRALAPYLGVLTLVLGAVFLVPALAHPRLLLAGPPVAPVPAGTGERKLEDMVPLPPEPAAPALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMW5</accession>
    <name>A8IMW5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative transglutaminase-like cysteine peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172193.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3670"/>
    <dbReference type="EnsemblBacteria" id="BAF89668">
        <property type="protein sequence ID" value="BAF89668"/>
        <property type="gene ID" value="AZC_3670"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3670"/>
    <dbReference type="eggNOG" id="COG3672">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_092032_1_1_5"/>
    <dbReference type="OMA" id="DHWGVVE"/>
    <dbReference type="OrthoDB" id="1500682at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="Transglutaminase-like_Cys_pept"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <end position="205"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    <sequence length="237" mass="25281" checksum="5C80EC6ECBAB3E7D" modified="2007-12-04" version="1">MFSAAITAFGQVFSPLLRGVLLKSVALAIGLLIVMAIGLNAALQHLATLPYPWLDTLVAILGGLGLVFGALYLTPAASSLVAGLFLDDVAEAVEKESYPNDPLGRPQPLGRSILASIRFFGVVLAVNLGALFLLLVPGVNIIIFYVANAYLLSREYFELAAMRYRTPEEARALRQAHAVQVFLAGLLIVPVLFIPFLNLITPVYGTALMVHLHRRLAPVPGAGMGQGPLIEGRKVSA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="AZC_3717"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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    </dbReference>
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        <location>
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        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="323" mass="34423" checksum="6EB3EE53E55375A4" modified="2007-12-04" version="1">MSLDVDQIVDRRRLRRKLTFWRVVGVLAVVAAVAVGSYVAVGRTVLASSPHVARVVIGGIIRNDRDRVKMLEEIGRSNARAVIVSIDSPGGTVTGAEQLYDALRQLAAKKPVVAVVEGMAASGGYIAAIGSDHIVSRRNAMVGSIGVIFQFPNVTDLLGKIGVTVEDIKSSPLKAAPNGYQPTSPEARAAINSLVVDSYGWFKGLVSERRKLSDARLAEVSDGRVFTGHQGLALQLVDELGDERTARAWLAREKGVPENLRVRTWKSESMGSEFGWLRGAAGALASALGFDTVAGILSQATQAAFEKAQLDGLLALWQAPAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172367.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3847"/>
    <dbReference type="EnsemblBacteria" id="BAF89845">
        <property type="protein sequence ID" value="BAF89845"/>
        <property type="gene ID" value="AZC_3847"/>
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    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OrthoDB" id="429006at2"/>
    <dbReference type="Proteomes" id="UP000000270">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="326"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="349"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="443"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="595"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="699" mass="74053" checksum="F8335C0C76DC77F0" modified="2007-12-04" version="1">MRLSINATLLSLFCFTTLIVTMLCAVALRSAYGAYASARQATAVAHIDRDIYVALANFRFERGEVGIALALASDKNQRNVANIASRREKVKHALEAALVAFKTYPLADAKSVVLMRDIESQFETVKDLRRQVDDQLALAPERRDGSVGQRFAADGGKLLDTLERLSTEVEADIRSLDPTLSQLILARAMGWATRTYTGISTLLINAAVAQDRPLTAEETKSLFANDAKADVAWGAVVEIAMADNAPPALRKAAQTAQDFYFAGTFKTLRDGIVNRITRGEKSGVSLPDWRQPIEIGLANFADVAGVAVNSLADIADANEDTARTTALIYAVVLLVSLALAGAGLAVVVGRVVRPISRLTAVMEDVAGGHLEVEVPGTARHDEIGAMAKTLLIFKESLLRNRQMEREAEENRRATEAQRRAAMLDLAARFETAVGGIIGQVASSSGVLFQTAQSMSRAAEQTSTRSTAVAAAAEEASTNVIMVASSAEELGASVEEISRQVMQSSQMSSSAVAEADRTGAVMRELAQAAARIGAVVELINTIASQTNLLALNATIEAARAGDAGKGFAVVASEVKELANQTGKATEEIAAQVNAIQSTTQEAVKVIESVGQQIRSMSDVATGISAAVEEQGIATREIVRNVDQAATGTNSVTGHIADVARTAQETGAAAHEVLSASSALSDQAKQLEVEMRRFLNTIRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPG8</accession>
    <name>A8IPG8_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">CheY-like response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheY</name>
        <name evidence="3" type="ordered locus">AZC_0620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169151.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0620"/>
    <dbReference type="EnsemblBacteria" id="BAF86618">
        <property type="protein sequence ID" value="BAF86618"/>
        <property type="gene ID" value="AZC_0620"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0620"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_69_12_5"/>
    <dbReference type="OMA" id="AAGAHEY"/>
    <dbReference type="OrthoDB" id="1630092at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="127" mass="14200" checksum="A2F406345F368899" modified="2007-12-04" version="1">MAVDLTMPVLVVDDYKTMVRIIRNLLKQIGFEDVDEASDGTEALAKLKERKYGLVISDWNMEPMTGYELLKRVRDDADLSDIPFIMVTAEAKSENVIAAKKAGVSNYIVKPFNAQTLKGKIDTVFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQ06</accession>
    <name>A8IQ06_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_0726</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169257.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0726"/>
    <dbReference type="EnsemblBacteria" id="BAF86724">
        <property type="protein sequence ID" value="BAF86724"/>
        <property type="gene ID" value="AZC_0726"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0726"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="ATHEMAE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="347"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="7">
        <location>
            <begin position="434"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="593"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="391"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="697" mass="72647" checksum="7A9296C14DBF7B5F" modified="2007-12-04" version="1">MNLSIKTTLIALFSVISAILAAICITSLLTAYRHNQTAEDAVRYVRADHGLFGAYSAYRLERADAGSVLPLPAERAQPVITGMMQRRVTSDTGIGVALAQLDALGVPEARAIAEKLRTVHAAIKRQRADVDAALQLPLEARDSKLGGRIMTESLGLLSQMEQTTDAVERQIRILEPSLLRFIVVRAAAGTARMGAGDASLIISAALREKRVFTPANTINFAAHNAQVQTGWTEVKTMVDAPDMPETLKSAMAKAQDHYFSGPVKTLRDQLAEDLSNGKLANVDAETWRGQSVPALESLAAVGLAAVDSLAKAADGLASDAWHLLLTYAGLLIVSLAAAIIGLVVVIGRVTRPISGLTAAVQALAGGNLAIEIPNTHRQDEVGSMAKAVLVFKEEMARNAALEAEAEAARLKAEAERREGMMRLAAEFESAVGGIIGSVASASTQLHGTARTMAEAARRTSEKSTAVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVQQSAEMSSVAVAEAQKTGTVIQDLAQAASRIGDVVGLISSIAEQTNLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTKQAVQVIEGVGSQIRKMSDVATSISAAVEEQGVATREIVRNVDQAATGTNSVTAHISEVAQTADETGSAAGQVLTAAAALTDQAKRLEAEMQRFLGTVRAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1992-08-01" modified="2022-05-25" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>P26484</accession>
    <accession>A8IIU0</accession>
    <name>FIXC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Protein FixC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">fixC</name>
        <name type="ordered locus">AZC_3449</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1991" name="Mol. Gen. Genet." volume="225" first="514" last="520">
            <title>Nucleotide sequence of the fixABC region of Azorhizobium caulinodans ORS571: similarity of the fixB product with eukaryotic flavoproteins, characterization of fixX, and identification of nifW.</title>
            <authorList>
                <person name="Arigoni F."/>
                <person name="Kaminski P.A."/>
                <person name="Hennecke H."/>
                <person name="Elmerich C."/>
            </authorList>
            <dbReference type="PubMed" id="1850088"/>
            <dbReference type="DOI" id="10.1007/BF00261695"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Could be required for the formation of a functional nitrogenase Fe protein. Probably accepts electrons from FixA/FixB and reduces a quinone.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF-QO/FixC family.</text>
    </comment>
    <dbReference type="EMBL" id="X55450">
        <property type="protein sequence ID" value="CAA39093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S14072">
        <property type="entry name" value="S14072"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171972.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P26484"/>
    <dbReference type="SMR" id="P26484"/>
    <dbReference type="STRING" id="438753.AZC_3449"/>
    <dbReference type="EnsemblBacteria" id="BAF89447">
        <property type="protein sequence ID" value="BAF89447"/>
        <property type="gene ID" value="AZC_3449"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3449"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050977_0_0_5"/>
    <dbReference type="OMA" id="GEWAVRI"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039651">
        <property type="entry name" value="FixC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43624">
        <property type="entry name" value="PTHR43624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0535">Nitrogen fixation</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000200684" description="Protein FixC">
        <location>
            <begin position="1"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA39093." evidence="1" ref="1">
        <original>DAPLER</original>
        <variation>TRRWSA</variation>
        <location>
            <begin position="65"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; CAA39093." evidence="1" ref="1">
        <original>TL</original>
        <variation>SV</variation>
        <location>
            <begin position="410"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000305" key="1"/>
    <sequence length="435" mass="48531" checksum="5DABF0F09C871F07" modified="2008-02-26" version="2">MIDEKFDAIVVGAGMAGNAATLTLARRGLKVLQLERGEYSGSKNVQGAILYADMLEKLVPDFREDAPLERHLVEQRFWMLDDRSHVGLHYRSEDFNEEKPNRYTIIRAQFDKWFSSKVKEAGATVLCETTVTELVQDAYGKVIGVKTDRSGGQIHADVVVLAEGVNGLLGTKAHLRERPKPEHVALAVKEMHFLPRETIEARFNLQGDEGVVIEAAGTISRGMTGMGFIYANKECISLGIGCLVSDFQKTGETPYGLLERFKSHPSVAPLIEGSEVKEYAAHLIPEGGFKAIPQLFGDGWVVVGDAAQLNNAVHREGSNLAMTSGRIAAEAIFQVKSRREPMSAKNLSLYKTMLEESFVLKDMKKYKDLPALLHINSQNFFLTYPQLVSKAMQNFVRVDGTPKVEKEKRTLRAFVEARSWFGLFGDAFRFARAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQZ9</accession>
    <name>A8HQZ9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3'(2'),5'-bisphosphate nucleotidase CysQ</fullName>
            <ecNumber evidence="7">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">3'-phosphoadenosine 5'-phosphate phosphatase</fullName>
            <shortName evidence="7">PAP phosphatase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cysQ</name>
        <name evidence="8" type="ordered locus">AZC_1082</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
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    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
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    <feature type="region of interest" description="Substrate binding" evidence="7">
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        <ligand>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022842"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
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            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <sequence length="272" mass="28888" checksum="CC027B541E96939B" modified="2007-12-04" version="1">MNPDYSELIMRSFILALLVLCGFSSLARADYAFVFTKTLCDNQADSMDAAWAASRFAGWGTQKLFFFDGANFQPVGHADAFDGFARVVIAAHGTVGRIADKSGARFAGIFQAHHPSTPTDVFLMVCSSAAQPHGGRSVVGELAARYPGAVVPAQTAIAHLTGATAACRLTGAVGVPVVGIGDATYRESVASSAEGDRIARQLVKDWKSTIYPPSNFTYARFCRKNHDADAYAPFIAQVQAAFMAPYLNLIRQNGVGNALYECGSATGTPICQ</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRK5</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1203</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169734.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1203"/>
    <dbReference type="EnsemblBacteria" id="BAF87201">
        <property type="protein sequence ID" value="BAF87201"/>
        <property type="gene ID" value="AZC_1203"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1203"/>
    <dbReference type="eggNOG" id="COG5343">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_075065_0_0_5"/>
    <dbReference type="OrthoDB" id="1740922at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="279" mass="30024" checksum="68953B957C0ECD73" modified="2007-12-04" version="1">MNLSEDDRQFVAEYVLGTLPAALRLMIRSRIEEERAFGAVSRQWEQRLSPLHELVVPVAPPADLWRDVAVNLIPRPIERTPDEPAKPADAKGKAKDGKGAKEAKGAKGPGGFAIPAAVDAAEAPPIIELAPNAAILSQMRRWRWATIGLGVLLVACAGTFGYREWDRSVAQRYFALLQEGRAASVLVRIDVSDGDVTVRPLVDPAPAGKSYQLWIVPDGQSPRSLGTFSSSFATRSDVVRKLGAKVAAKATLQVTLEPEGGTSELPSGDVLYSGRLLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRU7</accession>
    <name>A8HRU7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_4097</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4097"/>
    <dbReference type="EnsemblBacteria" id="BAF90095">
        <property type="protein sequence ID" value="BAF90095"/>
        <property type="gene ID" value="AZC_4097"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4097"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="SEYMFAR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="241"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="334"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="486"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="590" mass="61016" checksum="A98CCEBADDE60CF8" modified="2007-12-04" version="1">MDQVTAVAPPAAGPASTTSRCASEGVMYTNLSLIWKVVSLLLALGLVSIAGATYSDYALREVNASYMSVLEGPSAAAVAGARANRLVSDTLGALYQNIASISPEDNARAKAAIVKAREGTLTRLAEAARLSPQFAPRFQDVSDRFQSVVDKSCAETIRLANASSDGDGNARTMAEMNKTCEPAFRTLIEGLFALNGDLVKAATEAGRQTSAKAERSSVLVLVVICLATLLLLAAAAVLVRQKIVAPIRAMIEVMKGLGEGRLAQAVAGTDRKDEVGAMAGALEVLRGQLSDAETVRQAQAAREAEERRVLDRRNTLAEDFVARMTELSSAFAASSDQVAGSARNLSATAEQTSRQAQAVAEAAEEAAVNVQTVAASSEQLAASVREITGQVSHSAQVADVAFNEAETSNSRIGELATAATAIGDVISLIKGIADQTNLLALNATIESARAGEAGKGFAVVASEVKELASQTARATDEIAAKISEIQQSTQGTVSSMAEIMRVIASMKQISSSIAGAVEEQGAATGEIAQNCQRAADGTQKVTQNITGVGQAAELTGSASTELLALSEGLSGQASDLKRVVEAFVLDLRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRZ8</accession>
    <name>A8HRZ8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_4119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172639.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4119"/>
    <dbReference type="EnsemblBacteria" id="BAF90117">
        <property type="protein sequence ID" value="BAF90117"/>
        <property type="gene ID" value="AZC_4119"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4119"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_5"/>
    <dbReference type="OMA" id="YPLAIVC"/>
    <dbReference type="OrthoDB" id="490746at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="20"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="498" mass="52847" checksum="4C8150345679CB6F" modified="2007-12-04" version="1">MDTIGHYINGQAIGAGAGERSAPTFTPATGEQIGTVLLASAARVDEAVRAAAAALPAWAATPALSRARIMFRFKELLDRNLDRLAVLITREHGKTVEDAKGELIRGLEVVEFACGIPHLLKGEFSDQVGRGIDVFSQRHPVGVCAGITPFNFPAMVPMWMFPVAIACGNTFVLKPSEKDPSTALVLAELLAEAGLPKGVFNVVNGDKEAVDALLTHPKVAAVSFVGSTAVGEYVYRTACAHGKRAQALCGAKNHLVVMPDADLDKTVDALMGAGYGSAGERCMAVSVAVAVGGIGDALMEKLEPRVRALKVGPGTDPDSEMGPLITREHLAKVSGYVDLGVTEGAKLVVDGRGLKLQGHENGYYIGGCLFDDVTPDMRIYKEEIFGPVLSVVRVPAFDDALKLVNEHEYGNGTAIFTRDGDTARAFDYGVQAGMVGINVPIPVPVAFHSFGGWKRSIFGDRNVYGMEGVGFYTRVKTTTARWPNGQRGGAEFVMPVMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS75</accession>
    <name>A8HS75_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ychF</name>
        <name evidence="8" type="ordered locus">AZC_4150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172670.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4150"/>
    <dbReference type="EnsemblBacteria" id="BAF90148">
        <property type="protein sequence ID" value="BAF90148"/>
        <property type="gene ID" value="AZC_4150"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4150"/>
    <dbReference type="eggNOG" id="COG0012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018395_0_1_5"/>
    <dbReference type="OMA" id="VLRCFDN"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
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        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="term" value="F:GTP binding"/>
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        <property type="term" value="F:ribosomal large subunit binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:ribosome binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="TGS_YchF_OLA1"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="YchF_OLA1_ATPase"/>
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        <property type="entry name" value="ATPase_YchF/OLA1"/>
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        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
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    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="TGS-like"/>
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        <property type="entry name" value="TGS-like_dom_sf"/>
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        <property type="entry name" value="YchF_C"/>
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        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
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    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="6">
        <location>
            <begin position="3"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="7">
        <location>
            <begin position="280"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="365" mass="39546" checksum="8965F9DADF9E50F3" modified="2007-12-04" version="1">MGFKCGIVGLPNVGKSTLFNALTQTAAAQAANYPFCTIEPNVGDVAVPDPRLTALAEIAGSGQIIPTRLTFVDIAGLVRGASKGEGLGNQFLANIRECDAIAHVVRCFEDGDVTHVEGKVSPVDDIETIETELMLADLESLEKRAAALEKKARTLDKEGKDTLDLMQRALVLLRDGKPARLVDVKPEERKLFDMLGMMTAKPVLYVCNVEEASAKDGNALSAQVFERAKAEGAKAVVVSAKIESEIAILPEEEQREYLEAIDLDEPGLNRVIRAGYDLLDLATYFTVGPKEARAWTITKGTKAPAAAGVIHSDFEKGFIRAETIAYADYIQHKGESGAREAGRLRLEGKEYVVQDGDVLHFRFAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="106" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSI3</accession>
    <name>A8HSI3_AZOC5</name>
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        <recommendedName>
            <fullName evidence="3">Malate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mdh</name>
        <name evidence="9" type="ordered locus">AZC_4186</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the LDH/MDH superfamily. MDH type 2 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172706.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4186"/>
    <dbReference type="EnsemblBacteria" id="BAF90184">
        <property type="protein sequence ID" value="BAF90184"/>
        <property type="gene ID" value="AZC_4186"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4186"/>
    <dbReference type="eggNOG" id="COG0039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040727_2_0_5"/>
    <dbReference type="OMA" id="TKGMERG"/>
    <dbReference type="OrthoDB" id="870724at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01517">
        <property type="entry name" value="Malate_dehydrog_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010945">
        <property type="entry name" value="Malate_DH_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23382">
        <property type="entry name" value="PTHR23382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01759">
        <property type="entry name" value="MalateDH-SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="7">
        <location>
            <begin position="6"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="8">
        <location>
            <begin position="158"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="327" mass="34590" checksum="E2E65548FCB7E2C9" modified="2007-12-04" version="1">MTKPAVRVAVTGAAGQICYSLLFRIANGDVYGKDQPVILQLLDLPQAQNAVKGVVMELEDCAFPLLAGVVITDDPKVAFKDVDAAFLVGARPRSKGMERADLLLANAEIFKVQGAALNEVAKRDVKVLVVGNPANTNAYITAKSAPDLPAGNITAMLRLDHNRALSQFAAKIGANSADIEKLVVWGNHSPTMFADYRFATVKGQPLPKLVNDEDWYRGTLIPTVGKRGAAIIEARGLSSAASAANAAVDHMRDWIHGTNGGWVSMGIASDGSYGIPEGIVFGFPAVCANGSYEVVKGLEIDAYAQSMLDITLKELLEERAGVAAIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSP7</accession>
    <name>A8HSP7_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">DNA repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">radC</name>
        <name evidence="8" type="ordered locus">AZC_4204</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172724.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4204"/>
    <dbReference type="EnsemblBacteria" id="BAF90202">
        <property type="protein sequence ID" value="BAF90202"/>
        <property type="gene ID" value="AZC_4204"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4204"/>
    <dbReference type="eggNOG" id="COG2003">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_073529_0_0_5"/>
    <dbReference type="OMA" id="AMPDYEL"/>
    <dbReference type="OrthoDB" id="1833204at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
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        <property type="match status" value="1"/>
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        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="112"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="234" mass="25836" checksum="8948500C549EF11F" modified="2007-12-04" version="1">MAGEPDDGVEDAPHFHGHRDRLRARFRDAGAQALADYELIELILFRAIPRRDVKPLAKALVERFGSFAEVIAAPPRLLAEIPGVKDAIITELKLVEAAAHRLAKGQVKRRPVLSSWSAVLDYCRSAMAFADKEQVRVLFLDKRNQLIADEVVQTGTVDHAPVYPREVVKRALELSASALILCHNHPSGDPTPSRADIDMTRKIIDVAKPLGIELHDHIIVGKEGHASLKGLRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
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        <name evidence="5" type="ordered locus">AZC_4258</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172778.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4258"/>
    <dbReference type="EnsemblBacteria" id="BAF90256">
        <property type="protein sequence ID" value="BAF90256"/>
        <property type="gene ID" value="AZC_4258"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4258"/>
    <dbReference type="eggNOG" id="COG1196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001042_2_2_5"/>
    <dbReference type="OMA" id="HNKIAME"/>
    <dbReference type="OrthoDB" id="1149850at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="4">
        <location>
            <begin position="505"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="170"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="289"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="635"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="858"/>
            <end position="988"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1150" mass="125463" checksum="BA32F206CD07CDB2" modified="2007-12-04" version="1">MKFNRLRLVGFKTFVEPTDLLIEPGLTGVVGPNGCGKSNLVEALRWVMGESSHKAFRANDMDDVIFSGTTGRPARNTAEVALQLDNAERTAPAGFNDHDLIEVVRRIDRGQGSHYRINGRDVRARDVNMLFADASTGARSPALVRQGQIGEIVGAKPAARRRILEEAAGVAGLHARRHEAETRLKAAETNLLRLEDVITQLAGQVEGLRRQARQAVRYRALAAEIRKYEATLLWLRWSEVTRTLADAERTLEASVREAAECTRAQAEAARLQAIAAHALPALRQADTEAAAALQRLTLARVELDKEEERLGARRLDLERRLAQLTQDLERETALSADAEGVLARLEEEELTLTEEQEASVLAREEAEAILDTAQEAMAAAEDDLDAKTRAYADASARRTTLDQTIRDIRQRLLRTEAERVSVEAEERRLKLDAGTSDLEAKRMEADAARERLAFAEEAATDAEAAHQSARRALEEVRPAVAEAERKFGRLDTEVRTLSKLLQSSSGAFPPVADLLTVTKGYEMALGAALGDDLDLPVDTAAPARWAGSQPQAGDPALPPGAGPLADEVSGAPALLRRLGQIGIVEPADGPRLQAQLKPGQRLVSKAGDLWRWDGVIAAADAPTAAARRLAERNRLADLQLEADLAREAVEEARDMLALRDADLRAAAGLETQAREARRTAQRAAEIAREAEANAERKASAHIARLSALTEARERLTAARAEAEERLAEAEASLAELEQPALIDATLAAARGVVAQARGAVAEAKARLDGFERERSQRLRRLEAIASERRSWTSRAGGAGERLAAIAARKAETETELATTEEMPAQFLFQRRTLLGKIEAADEARRAAADKLVEGESALAAADRAARAALEAMSAAREETARAEARLDAARQRRDDVQREITEALDGPPESAREHAELVDDGRQPDISAIEIALERAKRERERLGAVNLRAEIELTETETQHDTLVRERDELNEAIRRLRGAIASLNREARERLQASFAVVDGHFRKLFDTLFGGGEAQLVLTDADDPLEAGLDIIAKPPGKKPQSLSLLSGGEQALTAMALIFAVFLTNPAPICVLDEVDAPLDDSNVERFCTLMDEMTRLTDTRFLVITHNPISMAHMDRLFGVTMAERGVSRLVSVDLQSAERLREVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTP0</accession>
    <name>A8HTP0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative chitinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0857"/>
    <dbReference type="CAZy" id="GH19">
        <property type="family name" value="Glycoside Hydrolase Family 19"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86855">
        <property type="protein sequence ID" value="BAF86855"/>
        <property type="gene ID" value="AZC_0857"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0857"/>
    <dbReference type="eggNOG" id="COG3179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3409">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1037496_0_0_5"/>
    <dbReference type="OMA" id="RIINGGY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="236"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="301" mass="31776" checksum="CFA24A71D6D12156" modified="2007-12-04" version="1">MCPQSGDHPMRAIDIVRRVAPKARPEYLAAFEAGEAQLEAASVTTPLRLANLLAQVLHETGGLTIVRESGAYSAPRILAIFGRGVHSAAVTPAEAERLAGDGPALFERVYGLGNPRMAAQLGNTQPGDGWKYRGNGLLQTTGRGQHREMGQRAGVGDLFERTPELVTAAELALKPALAEWTRGGCNTLADKGDIRQITRIINGGYNGLPDRQEWLDRIWSQIGTGALWRAAGADDATADLQESLNALGYSLTVDGRQGPATTAAIRDFQSRNGLKADGIAGPVTLAALAARLAPAKSPKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU83</accession>
    <name>A8HU83_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0917</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="STRING" id="438753.AZC_0917"/>
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    </evidence>
    <sequence length="309" mass="33726" checksum="ADE44DAD91D753CD" modified="2007-12-04" version="1">MSNSRHVCIVETAPMTANDTALHTFIQQGENMRSHEAFAGALRRYALDLVRLYRSSPILNKIVNEEGRFLISSLALQLHLHRDPRDPADGLTLSRLRELCAAHGVASPGRVTAFLGLMRMAGFVAPKPTEDRRSKLLVPTARLWDHVRIYTVIHMRGIEALYPGTSYLARLDHDAAFLENFHRAAGGYYLRGTRLPDGFPELAVFTSADAGYMVLLSIFLQLPLEGGRARPGTVDLPLTPTAKRFGVSRSHLVNLLRAAQAAGFLEVSGSGGRGVDVAPSLISLLERWFGANMALMSQSASEAALRAAA</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
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    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
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    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="GO" id="GO:0071972">
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        <property type="entry name" value="LD_TPept_cat_dom"/>
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        <property type="match status" value="1"/>
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        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
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        <location>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="6">
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            <dbReference type="Pfam" id="PF03734"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
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    </evidence>
    <sequence length="222" mass="24111" checksum="C5EEFDE7E831150F" modified="2007-12-04" version="1">MSFKTLRLAAALQLGLLVLAGAAHAQAFGTRPTPNASIPGATAPRGTPGATLDIGDQPGLVPPEDDEAQLDPAYRRQPVYFRTTEAPGTIIISTSDRFLYLVEGNNRAMRYGIGVGRDGFQWQGLEKISRKAEWPDWTPPAEMIQRQPYLPRFMAGGPGNPMGARALYLGQTVYRIHGTNQPETIGYAVSSGCFRLVNSDIIDLYSRVPVGTKVIIRQAVTL</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <end position="222"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="11" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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    <reference evidence="10 11" key="4">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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    <comment type="similarity">
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <evidence type="ECO:0000313" key="2">
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    <sequence length="311" mass="33804" checksum="9432EF06A825BFF2" modified="2007-12-04" version="1">MSRVELAFPVSSAAAFRAELIAAGLLIPTGVDGLYGRGAAYETVADALEAAITRLAAADAPERMRFPPVMSRQEFIASGYLKGFPHLAGTVNCFCGNEADHRRMLACIEAGEDWDDLQQPSEVVVTPAACYPVYPVVAAQGPLAEAGRLVDVSSYCFRHEPSVDPCRMQMFRMRELVRIGSEAQVLAFRDGWMARASRWLETLGLPSATAPASDPFFGRGGKIMAAGQMEQLLKFELLVPVGSTSEPTACISCNYHMTHFSEIWPLRDAAGGMVRSGCVAFGIERLTLALFRHHGFDARLWPAGVRAELFV</sequence>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
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    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Akiba N."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF90529.1"/>
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    <evidence type="ECO:0000256" key="1">
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Yamada M."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_4559"/>
    <dbReference type="EnsemblBacteria" id="BAF90557">
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    <dbReference type="eggNOG" id="COG0053">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Cation_efflux_TMD_sf"/>
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    <dbReference type="Pfam" id="PF01545">
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF161111"/>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="8">
        <location>
            <begin position="207"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="8">
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            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="295" mass="31536" checksum="1A91A154BB3C95EE" modified="2007-12-04" version="1">MSRNLQVAAASVLIGVIVLALKGAAYWVTGSIALLSDALESIINVAASLAAFFALQISGRPADDNHPYGHHKAEYFSAVLEGVLIVVASLSILREAYYGFLEPHLPEQPLNGMLLNGAATIINAVWCVVLLRIGKARRSPALIADGKHLMTDVVTSVGVLIGFVLVPVTGWPQLDPILAGLVAINILWTGWGLMRESVGGLMDAAPPPDVVGRIRELVSTHAAGAIEAHDLRTRHAGRMTFVEFHLVVPGDMTVAAAHVICDRIERALEEEMDDTIITIHVEPEGEAKHRGVVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZG6</accession>
    <name>A8HZG6_AZOC5</name>
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            <fullName evidence="6">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)</fullName>
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        <alternativeName>
            <fullName evidence="6">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
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    </protein>
    <gene>
        <name evidence="6 7" type="primary">ispG</name>
        <name evidence="7" type="ordered locus">AZC_4581</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + H2O + oxidized [flavodoxin] = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:43604"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:10623"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IspG family.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.3" evidence="6"/>
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        <property type="protein sequence ID" value="BAF90579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012173100.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF90579">
        <property type="protein sequence ID" value="BAF90579"/>
        <property type="gene ID" value="AZC_4581"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4581"/>
    <dbReference type="eggNOG" id="COG0821">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042258_1_0_5"/>
    <dbReference type="OMA" id="PTCGRTQ"/>
    <dbReference type="OrthoDB" id="665306at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016425">
        <property type="entry name" value="IspG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="PTHR30454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004640">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="SSF56014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="357"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="434" mass="46106" checksum="10FE2FCD72035567" modified="2007-12-04" version="1">MSMVPVVPDELLEAGPAVRRPTVPVPVGKVIVGGDAPVVVQSMTNTDTADIDGTVRQVAALARAGSEIVRITVDRDESAAAVPRIKERLLRQGIDVPLVGDFHYIGHKLLADHPACAQALDKYRINPGNVGFGAKKDRQFSAIVETAVRHDKAVRIGANWGSLDQELLTALMDENAKLPKPAEARAVTREALIRSALMSAALAEEIGLPRSRIILSAKVSAVQDLIAVYTELSRRSDYALHLGLTEAGMGSKGIVASTAAMGYVLQQGIGDTIRVSLTPEPNGDRTREVQVAQEILQTMGLRTFVPLVAACPGCGRTTSTTFQELAKSVQDMIRERMPEWKKSYPGVEALNVAVMGCIVNGPGESKHADIGISLPGTGEIPSAPVYMDGKKVGTLRGPNLQVEFRKMVEDYVAKRFGVGAAGEAAAPAPVDAAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZS2</accession>
    <name>HIS8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisC</name>
        <name type="ordered locus">AZC_4619</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173138.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HZS2"/>
    <dbReference type="SMR" id="A8HZS2"/>
    <dbReference type="STRING" id="438753.AZC_4619"/>
    <dbReference type="EnsemblBacteria" id="BAF90617">
        <property type="protein sequence ID" value="BAF90617"/>
        <property type="gene ID" value="AZC_4619"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4619"/>
    <dbReference type="eggNOG" id="COG0079">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017584_3_3_5"/>
    <dbReference type="OMA" id="YPDMACT"/>
    <dbReference type="OrthoDB" id="1248286at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0032">Aminotransferase</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000319743" description="Histidinol-phosphate aminotransferase">
        <location>
            <begin position="1"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="378" mass="40252" checksum="0D8AB24265FA8072" modified="2007-12-04" version="1">MSVSAKETQRHPARPEPRPGVLAISAYVPGKSHAAGVEKVFKLSSNETPLGPSPKAIAAFQSAGTNLQDYPDGSSTALREAIGKAMGIDPDRIICGAGSDEILNLIAHAYVGPGDEAIHCAHGFLVYKIATLGAGGVPVVVPDREDLQMDVDAIIGAVTERTRVIFLANPNNPTGTYLPFNEVRRLHAALPPNVLLVLDAAYSEYVRRNDYETGLELALSAENVIMCRTFSKIHGLAALRIGWAVASEAVIDALNRIRGPFNMNAPAIAAGAAAILDAEHVERSIAHNDQWLSWLTTELTALGLTVTPSVGNFVLIHFPKTPGRTAAEADAFLTRRGLILRAVASYGLPDSLRMTIGTEEANRLVVQALSDFLSGAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8I039</accession>
    <name>A8I039_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">argH</name>
        <name evidence="8" type="ordered locus">AZC_4662</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173181.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4662"/>
    <dbReference type="EnsemblBacteria" id="BAF90660">
        <property type="protein sequence ID" value="BAF90660"/>
        <property type="gene ID" value="AZC_4662"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4662"/>
    <dbReference type="eggNOG" id="COG0165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_2_3_5"/>
    <dbReference type="OMA" id="KKNPDVF"/>
    <dbReference type="OrthoDB" id="751464at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="8"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="365"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="462" mass="50124" checksum="7D61171E1F880996" modified="2007-12-04" version="1">MSNKMWGGRFSTGPDAIMEEINVSIGFDQRLYAQDIAGSKAHAAMLSAQKIIAAKDAQKIQKGLDTILSEIEAGKFTFRRDLEDIHMNVESRLAELIGAPAGRLHTARSRNDQVATDFRLYVRDTIDTLDEQMADLQRALAEKALAHAGTVMPGFTHLQNAQPVTFGHHLMAYVEMLGRDRGRFADARKRLNESPLGSAALAGTSFPIDREATAAALGFDRPTANSLDGVSDRDFVMETLAAASICAVHLSRFAEEIVIWTSPAFGLVKLTDAFTTGSSIMPQKRNPDAAELARAKSGRIIGALTGILVVMKGLPLAYAKDTQEDKEGTFDALSALSLVIAAIAGMVRDMEPEATRMKAAAGQGYATATDLADWLVRTLNIPFREAHHVTGRIVALASERGVPLHRLSLEEMQGVEKRITQDVFSVLSVTNSVRSRTSYGGTAPARVRQQARRWLKKLGPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0F4</accession>
    <name>A8I0F4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Type-5 uracil-DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_1251</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169782.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1251"/>
    <dbReference type="EnsemblBacteria" id="BAF87249">
        <property type="protein sequence ID" value="BAF87249"/>
        <property type="gene ID" value="AZC_1251"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1251"/>
    <dbReference type="eggNOG" id="COG1573">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083279_0_0_5"/>
    <dbReference type="OMA" id="CVPPQNK"/>
    <dbReference type="OrthoDB" id="1529383at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033958">
        <property type="term" value="F:DNA-deoxyinosine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10031">
        <property type="entry name" value="UDG-F5_TTUDGB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044147">
        <property type="entry name" value="UdgB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="35"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="211" mass="23120" checksum="BE248C7BF2F513B6" modified="2007-12-04" version="1">MLADPGRDCPLCPRLVSFRSTWRAAEPSWFNAPVPTFGPQEARLLIVGLAPGLRGANRTGRPFTGDYAGDLLYETLIHFGFARGTYRADPDDGLELIDARIVNAVRCVPPENKPTTEEIRTCRPFLAAAMAQMPRLSAIVALGKIAHDSVVVTLGERMSRAPFGHGTRREIGGHTVFGSYHCSRYNTNTGVLTPEMFRAVFSQVRSFLDAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2C5</accession>
    <name>A8I2C5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">recJ</name>
        <name evidence="9" type="ordered locus">AZC_1851</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Liu CT."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Suzuki S."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170552.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2025"/>
    <dbReference type="EnsemblBacteria" id="BAF88023">
        <property type="protein sequence ID" value="BAF88023"/>
        <property type="gene ID" value="AZC_2025"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2025"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_0_5"/>
    <dbReference type="OMA" id="CYTLKVA"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="160" mass="18105" checksum="3C8BBF0DF9268D6E" modified="2007-12-04" version="1">MKLDQIDVKILSELQKNGRITNVELAGLVNLSPSPCLMRMKKLQSEGYITGYSARINVGKLGQTLTVFTEVTLKNHRQIDFARFVAAVDKLDSVMECHLISGGYDYLVKFVTRGIADYQETMERLIDQDIGIDKYFSFVVLKSPIVKTHMPLTSLFRPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3J8</accession>
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        <submittedName>
            <fullName evidence="8">ABC Fe+3 hydroxamate (Ferrichrome) transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1623</name>
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    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1623"/>
    <dbReference type="EnsemblBacteria" id="BAF87621">
        <property type="protein sequence ID" value="BAF87621"/>
        <property type="gene ID" value="AZC_1623"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1623"/>
    <dbReference type="eggNOG" id="COG0609">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013016_7_3_5"/>
    <dbReference type="OMA" id="APNIARH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="435"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="506"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="597"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="620"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="650" mass="65710" checksum="7DC404578C13FEDC" modified="2007-12-04" version="1">MPRAPLAVAGLALLALTLCVMGLLRQPVLPGDPATARALEQVVLWHSLLPRAVVALLAGAALGLSGALLQRVLRNPIADPSTLGIASGAQLALTASALLIPALAEWPREVVALMGGVTAVGLLLMLSWKRGLEPITVVLSGMTLSLICAALSSALVLARGEYVLSLFVWGAGSLHQQSWGPALGLAWRFAFGLAAAVLLLRPLSVLTLDDSSARSLGMAVNGARLAIIALAVWLAASVVALVGIIGFVGLAAPAFARLAGARTPRAQLLLAPLLGALLLWLTDGLVQVLGADVLPTGAATGLIGGPLLLWLLPRLKHVQRPQAAAPTGRRLSHPLRGLLFLAGGLALLILAALLIGRSYEGWRLATGALFEALAPFRVPRVVAAAAAGALLGAAGTLMQRLTGNPLAGPEVLGVSAGAGVGLSVVLLLLPAPTVAVMMGGSAAGALVALLGILAFALATGFGPERLLLGGIALGAASLAFISAVLASGDARAFLLLGWMAGTTDRVGSVEAGAAVGLVLLLVPPLLLASRWLDILPLGSTMARALGVPLLASRLLLALAAALMTACAAFIVGPLSLVGLIGPHLARLSGFARGAHQLLAAALIGAGLMVLADWLGRTLAFPYQIPVGLFAALVGGHYLIWLLRRSPGTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3T8</accession>
    <name>A8I3T8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fis-type</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_1653</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MipA/OmpV family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1663"/>
    <dbReference type="EnsemblBacteria" id="BAF87661">
        <property type="protein sequence ID" value="BAF87661"/>
        <property type="gene ID" value="AZC_1663"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1663"/>
    <dbReference type="eggNOG" id="COG3713">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062990_2_1_5"/>
    <dbReference type="OMA" id="LGEWQYS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010583">
        <property type="entry name" value="MipA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38776">
        <property type="entry name" value="PTHR38776"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06629">
        <property type="entry name" value="MipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724180" evidence="5">
        <location>
            <begin position="29"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="285" mass="30640" checksum="41C476700B2E0D33" modified="2007-12-04" version="1">MRCMVSRSVLSSAALAALLSFGALEAHATDYPTAPPMPAPPGTQEDWYLTIGGSIRAVPEYPGSDDYTASPKLIFNISKASSLNAFRSVDDNPSIAFFDTGRFRIGAVGKLDLGRDQDDNAKLRGLGDVGTSVELGGFAEWYAFDWLRLRGELRYGFGGYEGLMGDLAADFIIPYQSWRFAVGPRLSFASSGYMQAYYGVTPLQAVSARFVGNPLPVYSAGGGVDAWGATAQLTKNFGNGFEAGVYGSYYRLVGDASDSPLTQSSNQFIAGVSLSYTFNMGKSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4T3</accession>
    <name>A8I4T3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Urease accessory protein UreG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">ureG</name>
        <name evidence="6" type="ordered locus">AZC_1769</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1769"/>
    <dbReference type="EnsemblBacteria" id="BAF87767">
        <property type="protein sequence ID" value="BAF87767"/>
        <property type="gene ID" value="AZC_1769"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1769"/>
    <dbReference type="eggNOG" id="COG0378">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072144_1_0_5"/>
    <dbReference type="OMA" id="VDLTIYV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01389">
        <property type="entry name" value="UreG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004400">
        <property type="entry name" value="UreG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31715">
        <property type="entry name" value="PTHR31715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00101">
        <property type="entry name" value="ureG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 4" id="KW-0996">Nickel insertion</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="5">
        <location>
            <begin position="9"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="204" mass="21443" checksum="E7892F84E10A9D6C" modified="2007-12-04" version="1">MTSNGPLRVGIGGPVGSGKTALMEALCKTFRARYNICAITNDIYTKEDARLLTVAGALEPERILGVETGGCPHTAIREDASINLRAVADMQAKFPGLEIVLIESGGDNLAATFSPELADITIYVIDVAGGEKIPRKGGPGITRSDFLVVNKTDLAPLVGADLSIMESDTQRMRGTRPYVFAAIRHGKGVEDVAAFIEKAGGLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I540</accession>
    <name>A8I540_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ordered locus">AZC_1810</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        </source>
    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
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        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
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        </reaction>
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    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
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    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
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    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
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    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
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    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
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    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="OMA" id="CDLILIM"/>
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        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
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    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
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    <keyword evidence="13" id="KW-0862">Zinc</keyword>
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            <begin position="143"/>
            <end position="146"/>
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            <end position="197"/>
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    <feature type="active site" description="Proton donor" evidence="10 12">
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        <ligand>
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    <feature type="binding site" evidence="10 13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
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        <location>
            <position position="36"/>
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        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
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    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>substrate</name>
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        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00001954"/>
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            <dbReference type="ARBA" id="ARBA00013188"/>
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            <dbReference type="HAMAP-Rule" id="MF_02227"/>
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    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
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    <evidence type="ECO:0000256" key="12">
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    <evidence type="ECO:0000256" key="13">
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    </evidence>
    <evidence type="ECO:0000256" key="14">
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="16">
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="5 10">Adenylosuccinate lyase</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170764.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2237"/>
    <dbReference type="EnsemblBacteria" id="BAF88235">
        <property type="protein sequence ID" value="BAF88235"/>
        <property type="gene ID" value="AZC_2237"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2237"/>
    <dbReference type="eggNOG" id="COG0015">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030949_0_1_5"/>
    <dbReference type="OMA" id="ASSCEKI"/>
    <dbReference type="OrthoDB" id="347727at2"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADSL_C" evidence="11">
        <location>
            <begin position="352"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="435" mass="48674" checksum="64AD6F6F256B2305" modified="2007-12-04" version="1">MIPRYSRPQMADIWSPETRFRIWFEIEAHAADAMAELGIVPKEAAKVIWEKGANATFDVERIDAIEREVKHDVIAFLTHLAEIVGPDARFVHQGMTSSDVLDTCLAVQLTRAADLLIADVDNLLAILERRAFEHKLTPTVGRSHGIHAEPTTFGVKLAIAHAEFQRSRARLVAARAEIATCAISGAVGTFAHIDPRVEQHVAEKMGLTVETVSTQVIPRDRHAMFFAVLGVVASSVERLATEVRHLQRTEVLEAEEYFSEAQKGSSAMPHKRNPVLTENLTGLARMVRGYVTPALENVALWHERDISHSSVERMIGPDATVTLDFALARLAGVMDKLVVHADNMQKNMDKLGGLIHSQRVLLALTQKGASREDSYRLVQRNAMKVWRGEGDFRAFLLADEEVRKYLSEDDINEKFDLGYHFKNVDQIFTRVFGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5L6</accession>
    <name>A8I5L6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2296</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170823.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2296"/>
    <dbReference type="EnsemblBacteria" id="BAF88294">
        <property type="protein sequence ID" value="BAF88294"/>
        <property type="gene ID" value="AZC_2296"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2296"/>
    <dbReference type="eggNOG" id="COG1399">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088841_0_1_5"/>
    <dbReference type="OMA" id="GLDPYPR"/>
    <dbReference type="OrthoDB" id="1665714at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="174" mass="18763" checksum="4886DF7F4532ED0E" modified="2007-12-04" version="1">MTDLPYSQILAVADIPPQGLELTLKPDADVCAAMARHLDIPAVSEVVAKLRLTQEKADGARVTGRVSAKVTQISVVSLEPFESSFSEELDVRFATADIIAREVADAPEESDFDPPDLIENGSIDLGLLVTEFLALGLDPYPRKDGEVFKAYQESDPAEAPVSPFAALARLKEKP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8I711</accession>
    <name>DADA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-amino acid dehydrogenase</fullName>
            <ecNumber evidence="1">1.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dadA</name>
        <name type="ordered locus">AZC_2066</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Oxidative deamination of D-amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>A + a D-alpha-amino acid + H2O = a 2-oxocarboxylate + AH2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:18125"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:35179"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text>Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DadA oxidoreductase family.</text>
    </comment>
    <dbReference type="EC" id="1.4.99.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170593.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I711"/>
    <dbReference type="SMR" id="A8I711"/>
    <dbReference type="STRING" id="438753.AZC_2066"/>
    <dbReference type="EnsemblBacteria" id="BAF88064">
        <property type="protein sequence ID" value="BAF88064"/>
        <property type="gene ID" value="AZC_2066"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2066"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_9_2_5"/>
    <dbReference type="OMA" id="NDLYPRG"/>
    <dbReference type="OrthoDB" id="573710at2"/>
    <dbReference type="UniPathway" id="UPA00043">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF88084.1"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <property type="protein sequence ID" value="BAF88084"/>
        <property type="gene ID" value="AZC_2086"/>
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    <dbReference type="KEGG" id="azc:AZC_2086"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF88084.1"/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the heme-copper respiratory oxidase family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF88140.1"/>
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    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2142"/>
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    <dbReference type="KEGG" id="azc:AZC_2142"/>
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="544" mass="60290" checksum="72ED25DCF3B5A566" modified="2007-12-04" version="1">MSEAPMSASSFSGGPVSEAEWVEARRASLLNLPQAHADGRLPSLLLPYQARGIDILDDPRTRVLVVEKSRRIGYTWGLAAHAVLKASRAREARGMDVMYISYSQEMTREFVDAAAMWARAFALAAAAEEEFLFADADPDDPGETREIKAFRIRFASGFEIIALSSAPRSLRGKQGLVIIDEAAFVESLKELLKAALAFLMWGGQVVVVSTHNGDANPFNELVQDVLAGRKPYAHVRIDFDQALKDGLYQRICLVTGDSWTPETEAAWRSQIIAFYGEGADEELFCTPSEGTGAWLPGPLVEARMREGIPVLRWELPADFLHRPRLIREAMVARFTEEVRRALDRLDPNRQHALGFDFARVADLSVLWVLALSPTTRRETVLVIEMRRIPYDEQATLTVDVIRRLPRFMAAVFDATGAGEYVAENAQRRISLSACIAQKLSVEWYRTQMPPLKAAFEDDMVTVPKDAEILADLRLVQTVRGVAQPPTLRTGDTGRKRHADAAVALALAYHATRISVLEYDYQTGSDLDAVAAGDEDDTSGGRALW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8M9</accession>
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        <submittedName>
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    <organism evidence="4 5">
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    <reference evidence="4 5" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171206.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2682"/>
    <dbReference type="EnsemblBacteria" id="BAF88680">
        <property type="protein sequence ID" value="BAF88680"/>
        <property type="gene ID" value="AZC_2682"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2682"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_4_5"/>
    <dbReference type="OMA" id="HKVDWRI"/>
    <dbReference type="OrthoDB" id="685252at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721532" evidence="2">
        <location>
            <begin position="27"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="37"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="269" mass="29503" checksum="A5953A13A54610B9" modified="2007-12-04" version="1">MLKSLLAAGAIAVALAGALVPKAAEARTLDEIMKSGVIRVGVNPTLPPLGKFDDKNEIVGFDVDYAGEIAKLLGVKLEVVQVGSPDRIPFVTAGKIDFVMGAMTRNTDRAKVIDFTVPVHTEVLGVLTTKANTFTDWRQFDDPSVTFVQVRGSTPVKFIEENLPKAKVTLLDNYPDAVRALAQGRGTAMIDVIDFMGEHMSKHKVDWRIVETPIDVYYCSLGVAKGSTGLKDWLNVAIFDLYRKGKTEALWKKWFGMDMIKPVGAQPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8R2</accession>
    <name>A8I8R2_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Oligopeptide/dipeptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2694</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171218.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2694"/>
    <dbReference type="EnsemblBacteria" id="BAF88692">
        <property type="protein sequence ID" value="BAF88692"/>
        <property type="gene ID" value="AZC_2694"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2694"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_5"/>
    <dbReference type="OMA" id="HDLGVMS"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="7"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="333" mass="35690" checksum="90DF1EE0A7908B8A" modified="2007-12-04" version="1">MSAPALLEVCNLIRDYPAGPAPLFGRRATVRALDSIDLQVPKGSIFGIVGESGCGKSTLARIVMALDRPTSGNVLFDGDDLFLLPPARLAARRRDFQMVFQDPYGSLDPRSRIGRTIAEPLHVMPGAPRGKARTELVGRALESVGLKAADATRFPHEFSGGQRQRIAIARALITEPKLVVADEAVSALDLSVQAQVLNLLRALRDRRGITVLFISHNLAVIDCVADHVAVMYRGRIVERGPARAVFDQPLHPYTQLLIAAEPSLDQIGCGPRRPSPPVVPKVSAVAGQGCAFLPRCPRATERCAAEAPPLRAIADGRASACHHAEDLSPSLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
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    <name>A8I8S1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Peptide/opine/nickel uptake family ABC transporter permease</fullName>
        </submittedName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
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        <location>
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            <end position="385"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
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            <dbReference type="Pfam" id="PF00561"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88702.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="405" mass="43279" checksum="8B0D1968026BE85A" modified="2007-12-04" version="1">MRQEGSRKRRQFARAGTAPRLQPKGSGTGCQSARTSARSFAPGAPGAFRRAPKPMTASANSGSVATDLMPKELNRSADVPTPDAVSAPSRRDVLGLAAGAGLALTLGSMPAFAAGPSSPTSANGHTAMPSVTTKDGVEIFYKDWGPKEAQPIVFHHGWPLSSDDWDAQMLFFVSKGFRVVAHDRRGHGRSSQVSYGHDMDHYAADAFAVVEHLNLKNAVHIGHSTGGGEVARYVAKHGQPAGRVAKAVLVSAVPPLMLKTAANPEGLPLEVFDGFRKATAENRAQFFLDVPTGPFYGFNRPNAKVYPGVIQNWWRQGMMGSALAHYEGIKAFSETDQTEDLKTITVPTLVLHGEDDQIVPIADSAMKSIKLLKHGTLKTYPGYSHGMLTVDADVLNADILAFIKA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; alginate biosynthesis.</text>
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        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88808.1"/>
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    </evidence>
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    </evidence>
    <sequence length="379" mass="42307" checksum="5D3BCE5B43BC1FE1" modified="2007-12-04" version="1">MTMLSHHRRYLGAVVLVILALLLAANFVPDPLGRGVWRGRSRPPANEAQRLLWKVQDFSLYVQDNFGFRASLPALRRTVRAALDAPNDRNIYEGSNGHLFWGRENTPAQSSGDLVRAEAVERFVAMAKALQDELAPQGGRVVVAIPPNAQSVELRDLPDWQKDFTPRPTEYDLLLAGLKADGIAAVDLRKVLGEAPFTGPRYMRSDTHWTFASSVYAFNAALRAGGHPDWTVDPNVLIGPLEPAPPGDLVRTSRNARPVHDQNFVPRFQPPDAPIERSPVLRAPHEHPAFRPYVQRFRPEGPRVLIIGDSFTIGTWTRLFAGTPVAEAGWMHFSRRTLGYCGFDAADVKDFKPDLVILARTERLFPCLDDAWPDHLPEP</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
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        <property type="protein sequence ID" value="BAF88815.1"/>
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    <dbReference type="STRING" id="438753.AZC_2817"/>
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    <dbReference type="KEGG" id="azc:AZC_2817"/>
    <dbReference type="eggNOG" id="COG1538">
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    <dbReference type="OMA" id="YRKGDND"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="T1SS_OMP_TolC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="type_I_sec_TolC"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="513" mass="54884" checksum="D70B8136385F56C7" modified="2007-12-04" version="1">MSDLPRCAKKQLVIEPVGFLVWCRWIWSEFNPRVWLSDTARGGAAVRENSMSLATHFCRRLSVLAAAAVVSGLAWTSSVSAQTLETALGQAYVNNPSLNSQRAGTRATDESVPQALSGYRPNVSAGASVGGQYARTNSSGTIATNSLVPRSVNLTVSQTIFNGFLTASTTQKAESSVKGSRETLRNTEQTILLNAVTAYMNVLQGIALLELQNQNLAALQQELRATRDRFNVGEVTRTDVAQAEAQVATANYQVAQAVANLQAYKATYRQVIGVEPGKLTAPKSIEFMLPPTVDKAVAAGLSTHPAIQASKFAVDAAMFQVKMSEAGLAPVVSVQGQLAQGYDQNSAVDSTSSASVALNLTVPIYQGGAEYSAIRQSKELLTQARIEVDVNRDTVRANTVQYWGALEAAKAQIQSAQASVAANTLALEGVREEWRVGQRTTTDVLNAQTDLTTSKSNLVTAQRDRVVAAYSLLSSVGKLDAVTLGLKVPVYDARVHYDQVRDAWAGIRTPDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA46</accession>
    <name>A8IA46_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Twin-arginine translocation pathway signal</fullName>
        </submittedName>
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    <gene>
        <name evidence="7" type="ordered locus">AZC_2463</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2463"/>
    <dbReference type="EnsemblBacteria" id="BAF88461">
        <property type="protein sequence ID" value="BAF88461"/>
        <property type="gene ID" value="AZC_2463"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2463"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="373" mass="40702" checksum="E3D49A0A59D4C751" modified="2007-12-04" version="1">MRASSPRTHHKNPEADMTKTTTPFSAPLSRRSVLVGLGLAAGSAVFGLPRGAAALEGTLVVSNWGGDWNERTIKFVEAPLVESQGIKIVRDLGMEPERKAKLIAEKRLRRGTIDVIHINEGDSVELNGQDVLADIDFAKVPNYADVVPALKSKPFFVPWLYSGVTLIYNKDKVPNPPKSYAELWDKKWAGKLGLTNQLYFNYVMMAGLIKGGNVTNTEEGKKRLIELKELTQPRIYAAHQQLAAGLANGEVDIAINYKARGLQWANDGAPLAIQYPAEGAIAVMFGAALPKRAPSPELAYVYFNAMLDPKAMAGLAGASFYAPANAKAALSPELKAKIDFTAAEAAALKFPDYEHVAKNTAEWLEWWNKNIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAB6</accession>
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            <fullName evidence="2">N-carbamyl-D-amino acid amidohydrolase</fullName>
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    <gene>
        <name evidence="2" type="ordered locus">AZC_2488</name>
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    <organism evidence="2 3">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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    <dbReference type="HOGENOM" id="CLU_017584_4_3_5"/>
    <dbReference type="OMA" id="IHMEVGQ"/>
    <dbReference type="OrthoDB" id="554560at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
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    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
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    </dbReference>
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        <property type="entry name" value="SSF53383"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="41"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="395" mass="42720" checksum="182ECFD3D3B950BC" modified="2007-12-04" version="1">MMSSLVLPPALVPASRRSEVAPFIVMDVMEHAARLEAEGAKVIHMEVGQPAAPAPRTARKAAAAALERGQVGYTAALGIPSLRARIAKHYKEQHGFDLDPERVVVTNGSSGGFILAFLALFEAGDRVAIAAPGYPPYRHVLSALGCEPVLIETKAEDRFALTPETLRAAHAEKPLKGVLVASPANPTGTMMDRTALTALYAAAKELGLRFVSDEIYHGLDYAFPAVTAAEVAPDAVVINSFSKYFCMTGWRVGWMVVPEGMSRTMERLQQNFSISVPTLSQIAAEAAFDGREEMDAVKHGYEENRRILTEGLPKIGLEHFLPADGAFYLYADVSRFTGDSHAFATRLLDAAHVAATPGVDFDPFRGKQFLRFSYAGSAEDMRAAVARIGHFLSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBN6</accession>
    <name>A8IBN6_AZOC5</name>
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        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3097</name>
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    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171621.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3097"/>
    <dbReference type="EnsemblBacteria" id="BAF89095">
        <property type="protein sequence ID" value="BAF89095"/>
        <property type="gene ID" value="AZC_3097"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3097"/>
    <dbReference type="eggNOG" id="COG0477">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_46_6_5"/>
    <dbReference type="OMA" id="YERPRIF"/>
    <dbReference type="OrthoDB" id="1121832at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="30"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="456" mass="47021" checksum="7ED75059B9BE5BAF" modified="2007-12-04" version="1">MTRRSAADPTAAELVARYDGQAMGPRYWTTFAVLAGVATLDFADFFLIGFILAVIGPEWGLSYGQSAMILYGGGVGSILAALLWGSVSDARGRKRQIISGTIICGLSAGLIAFVPQGWWELIVALRILVGFGLAASATPVLTLVVEVTPTRHRTRVGSLFMVFSSLGILVAALSSGLLIETLGWRGVALLGFMPLVPALLTALFVPESLRWLVAVGRISQAMALVGEPGQAGAAAPQVEKGRGLIRSLGDLYERPRIFWQVVIVNAAALTVVFGYYLWGPTIMSAELGRSVGGTALYFVIISGCGILGRLSTAVVVPFTGRRPLGIVLALLAAVALACVSLSGGRTVAGVPMALISLSCAAFFCEGGLANSAPYAIEQYGARLGARAAGLAQAASGVGRIIGPLALALIAGSSNVVSPAFSAAAAAPAFLFFAGCMVLVSGAFVFLAVETNGRPID</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC08</accession>
    <name>A8IC08_AZOC5</name>
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        <recommendedName>
            <fullName evidence="3">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="3">dTTPase/UTPase</shortName>
            <ecNumber evidence="3">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="3">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="3"/>
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        <property type="protein sequence ID" value="BAF89143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012171669.1">
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        <property type="gene ID" value="AZC_3145"/>
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    <dbReference type="eggNOG" id="COG0424">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_040416_2_0_5"/>
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    <dbReference type="OrthoDB" id="1469203at2"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
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    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
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    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89143.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="206" mass="22267" checksum="7F6553B7520E6CB3" modified="2007-12-04" version="1">MNDRVQLVLASGSPRRLALLNQAGIQPDRLMPADVDETPERGELPRRLALRLAQQKGELVASRCREADIPALVIAADTVVAAGRRILPKPELQEEAEACLRLLSGRAHRVFTGLCLVTPKGRVRTRLVESRLRFKRLTSEDIAAYLACGEWRGKAGGYAIQGIAGSFVVKLTGSYTSVVGLPLAETVALLNGEGYPVRTGWVESAA</sequence>
</entry>
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        <submittedName>
            <fullName evidence="9">Sigma-54 factor</fullName>
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    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_3213</name>
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    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171737.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3213"/>
    <dbReference type="EnsemblBacteria" id="BAF89211">
        <property type="protein sequence ID" value="BAF89211"/>
        <property type="gene ID" value="AZC_3213"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3213"/>
    <dbReference type="eggNOG" id="COG3829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_8_0_5"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="HTH_Fis"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
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    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
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        <property type="entry name" value="Sigma_54_int"/>
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    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
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        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
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    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
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        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HTHFIS"/>
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        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SIGMA54_INTERACT_3"/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
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    </evidence>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="221"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="346" mass="37583" checksum="DF11E141200E2229" modified="2007-12-04" version="1">MGGRTRMSGGIPSRRFRTLESDKAEQFGRYHDHMAPIYDVAAEENGKAGFAADMTAYHLGGMLVGASGFSDHAIGRSKRKIARTDMDHLLVQLHKTGGLDADAEGNVVRVRAGDISLIDLGRPMDGHAKTSQTLDVILPRSQLPDLAQRRKTPHGAVLSGDSLMGGILGDFLLSLARRLDAATPRDAGLLTRAAADLITTCFQSETGVAAAQEGLLLAASERARRYIDANLSKAELVPVRVARELRMSRSSLYRLFEAEGGIAKYIRTRRLTTALYLLTHPAHAGMRIGEIAFRCGFSSEAHFSRAFRSEFDMKPSEARKRARFEPALAAASPGEGPWIASLRPSE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID68</accession>
    <name>TRMFO_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO</fullName>
            <ecNumber evidence="1">2.1.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Folate-dependent tRNA (uracil-5-)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Folate-dependent tRNA(M-5-U54)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trmFO</name>
        <name type="ordered locus">AZC_2889</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:16873"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.74"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:62372"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.74"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MnmG family. TrmFO subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.74" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171413.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ID68"/>
    <dbReference type="SMR" id="A8ID68"/>
    <dbReference type="STRING" id="438753.AZC_2889"/>
    <dbReference type="EnsemblBacteria" id="BAF88887">
        <property type="protein sequence ID" value="BAF88887"/>
        <property type="gene ID" value="AZC_2889"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2889"/>
    <dbReference type="eggNOG" id="COG1206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033057_1_0_5"/>
    <dbReference type="OMA" id="MHRNTFL"/>
    <dbReference type="OrthoDB" id="516534at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030698">
        <property type="term" value="F:5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047151">
        <property type="term" value="F:methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01037">
        <property type="entry name" value="TrmFO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004417">
        <property type="entry name" value="TrmFO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF2">
        <property type="entry name" value="PTHR11806:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00137">
        <property type="entry name" value="gid_trmFO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0274">FAD</keyword>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000346319" description="Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO">
        <location>
            <begin position="1"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01037"/>
        </source>
    </evidence>
    <sequence length="471" mass="50522" checksum="79A7E284403700DC" modified="2007-12-04" version="1">MSQTSLQPVHVVGGGLAGSEAAFQLAERGVPVVLHEMRPVRGTEAHHTDGLAELVCSNSFRSDDAQTNAVGVLHAEMRRAGSLILRCADANQVPAGGALAVDRDGFSQAVTAALAEHPLVEIRREEVTAIPPEEWDNVIIATGPLTSPALAQAVLELTGESALAFFDAIAPIVHLDSIDLSKAWFQSRYDKVGPGGTGADYINCPLDKEQYEAFVDALLASEKVPLRDFEAKTPYFDGCLPIEVMAERGRETLRFGPLKPVGLTNPHNPDVKPHAVIQLRQDNKLGTLYNLVGFQTKMRHGEQVRVFRTIPGLENAEFARLGGLHRNTYLNSPRLLDGTLRLKAAPRLRFAGQITGCEGYVESAAVGLMAGRFAAAERRGEALVPPPATTAHGALLAHITGGHIETVDAGPRSFQPMNVNFGLFPQLDVSPKGADGKRLRGSEKTLAKKRLLAERALSDMSAWLDTPAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDN5</accession>
    <name>A8IDN5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2968</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2968"/>
    <dbReference type="EnsemblBacteria" id="BAF88966">
        <property type="protein sequence ID" value="BAF88966"/>
        <property type="gene ID" value="AZC_2968"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2968"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031275_1_0_5"/>
    <dbReference type="OMA" id="VEGFMRG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88966.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="351" mass="36998" checksum="4270C43E03C45F3B" modified="2007-12-04" version="1">MVWGGRRPPAPNRSLPRFAMLSDWSVARAAAIACAVIALFLAAWAISDVLLLAFAAILVAIGLHGLAGAVTRYTGCPPRAALAVVCLLVAGLLGVVAYLFGNIISAQVRELFHRLPAAWETFQDEFHLRGMVDDLMRRAEAAATPSGATVLSAVRGVTSNIANVLVGIFLIVVGGLYFAMQPHFYRRLLISLFPPQHQDAAGRRVDGIGQSLRCFLQAQLIAMIVVGLLCGIGLAVLGVPAALALGLFAGLAEFVPMVGPVMAAIPALLLALTVGMETTFYTLLLFLVVQQVESNIISPLLQQELVSLPAAVTLFSVVAFGTLLGPLGLLLATPLTVLVFALCRPDDNCAI</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
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        <property type="evidence" value="ECO:0007669"/>
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        <source>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89001.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="253" mass="27084" checksum="B3B86610C23CF8F9" modified="2007-12-04" version="1">MTLSIQGLTKAYGGLRVVDEVRFEVPSGALVGVIGPNGAGKSTLFSLITGFLAADGGNVAFEGRALGRASPMERARAGMVRTFQVPREFSHLTVRENLMAAYPKQSGERLIDTFFRPGRVKAEEAAIAREVEETVAFLRLQKVADVPAGRLSGGQKKLVELGRALMTGARMILLDEPFAGVNPVLIEELSVRIRELNARGIGFLIIEHDLPALNKLVSTLHVMDRGQLIASGTPAEVLANPRVRDAYLGGAAA</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
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        <location>
            <begin position="6"/>
            <end position="27"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89031.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="176" mass="18560" checksum="0ED31FD13EC8009C" modified="2007-12-04" version="1">MTPILLSLFVIFAELSVLAFGGGNTILPEMQRQMVDVHHWMTAQQFSAMFALAQAAPGPNMMIVPMIGWRLAGLPGVLVTSLAKFGPSSLITAFALHLWERFKDRPWRRHIQQGLVPVTVGLVAASAALITEASVQNLTLALIAGASALAVLKTRAHPLAVLAAGAAIGLTGFGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <authorList>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0118"/>
    <dbReference type="EnsemblBacteria" id="BAF86116">
        <property type="protein sequence ID" value="BAF86116"/>
        <property type="gene ID" value="AZC_0118"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0118"/>
    <dbReference type="eggNOG" id="COG4566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1302831_0_0_5"/>
    <dbReference type="OMA" id="ATEIDCI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="88"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="211" mass="22590" checksum="089138570FD6E365" modified="2007-12-04" version="1">MTPPLLTGGRRAVPVTRGRAASAIRGCASGGSGGRVVDAGRANRPAAKPVYDIGGRELRVRWRDAGARRRTRGPACVEVSPEVSPVPTIAIIDDDEAVRRATESLIRSLGFGTRSFASAEDFLKSAERDQADCVITDIHMAGMSGVDLQSRLRAEGDMVPLIFITGYPEEKVRRQVDAAGAFGFLAKPFEGNAMIDCIDRALEARAARRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGU2</accession>
    <name>A8IGU2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0135"/>
    <dbReference type="EnsemblBacteria" id="BAF86133">
        <property type="protein sequence ID" value="BAF86133"/>
        <property type="gene ID" value="AZC_0135"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0135"/>
    <dbReference type="eggNOG" id="COG4166">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023171_0_0_5"/>
    <dbReference type="OMA" id="VLPKHWW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="156"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="666" mass="75021" checksum="9B6CF101B96AAAE1" modified="2007-12-04" version="1">MRGKCVRQRIFRYHFPLITPCFCRRVRRDMRSVLAGRRPAASSPESSMLVKIRRIALATAILACTAPAFAQAQQAAAPAPFRFATSLMGEPKYKPDFKHFDYVNPDAPKGGVVRFAEDGTFDSFNFVVPRGTVGAGIGNIYDTLTTQSRDEVATAYGLIAEGLSYPADFSSVTYRLRAEAKWQDGTPITPDDVVWSFQVLTKNNPGQAFYYRHVKSVEKTGQREVTFTFDQGGNRELPQIVGELLVLPKHWWTGTDANGKARDITQGTLEAPLGSGPYRIKSFVPGRTIVYERVKDYWGKDLPVNVGRNNFDELRYEYYRDDTVALEAFKADQYDWRIEPSAKNWATSYDFPAKQQGKVVLEMFENRASGVMQAFIPNLRRAKFQDPRVRRALNYALDFDGMNHTLFFDQYKRIGSFFSGTELASSGLPTGAELDILNGVKDKVPPGVFTTPYTNPDNPSEQDRRANLRKAADLLKEAGWQVKGKQLVNAKGDAFTLEILIASPAFERVALFYKPALERLGIQTSVRLVDSSQYVNRVRARDFDMIISGWGQSLSPGNEQRDYWGSDSADREGSRNYAGIKDPAVDALIEKIIYATDRQQLVAATHALDRVLLWNDYVIPAWTLGFTRTARWDRFAHPPALPQYSFEFPDIWWWDAAKAAKIGGGN</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGZ9</accession>
    <name>GPMA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="1">BPG-dependent PGAM</shortName>
            <shortName evidence="1">PGAM</shortName>
            <shortName evidence="1">Phosphoglyceromutase</shortName>
            <shortName evidence="1">dPGM</shortName>
            <ecNumber evidence="1">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gpmA</name>
        <name type="ordered locus">AZC_0156</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
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        </reaction>
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        <text evidence="1">Homodimer.</text>
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        <property type="entry name" value="PG_MUTASE"/>
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    <keyword id="KW-0413">Isomerase</keyword>
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            <begin position="1"/>
            <end position="206"/>
        </location>
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    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="1">
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            <position position="10"/>
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    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
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    <feature type="binding site" evidence="1">
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        <ligand>
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        <ligand>
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    <feature type="binding site" evidence="1">
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        <ligand>
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    <feature type="site" description="Transition state stabilizer" evidence="1">
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            <position position="158"/>
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    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <sequence length="206" mass="22858" checksum="A2CEDC703E52AC4F" modified="2007-12-04" version="1">MDRLLVLVRHGQSEWNLKNLFTGWRDPNLTDQGVSEARRAGALLAAEGLSFDVAYTSALTRAQRTCQLVLEEMGLTGLRTIADQALNERDYGDLSGLNKDDARAKFGEEQVHVWRRSYDISPPGGESLRDTVARVLPYFVQEILPSVLRGERTLVAAHGNSLRALVMVLERLSPEGIMKRELATGAPILYRLGADATVSEKRDILI</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89296.1"/>
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    </dbReference>
    <dbReference type="RefSeq" id="WP_012171821.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3298"/>
    <dbReference type="EnsemblBacteria" id="BAF89296">
        <property type="protein sequence ID" value="BAF89296"/>
        <property type="gene ID" value="AZC_3298"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3298"/>
    <dbReference type="eggNOG" id="COG0318">
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    <keyword evidence="1" id="KW-0007">Acetylation</keyword>
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        <location>
            <begin position="28"/>
            <end position="406"/>
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        <location>
            <begin position="415"/>
            <end position="490"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="508" mass="54618" checksum="402DD8B52A72FA11" modified="2007-12-04" version="1">MTSQNHFFAAIRAAMPDLSKPLATHPDGAMETYGDALALSARLANVLVKRGVKPGDRVAVQVEKSWTAFVLYLAALRAGAVYLPLNTAYTLAELEYFLSDAEPTVVVVRPEVAGDVKALAAKLGVPHVETLGSDGKGSLTEAAAGESESFEDVPRAADDLAGILYTSGTTGRAKGAMLTHENLLSNAVTLRDYWRFTSDDVLIHALPIFHTHGLFVAGDIILMAGASMIFCPKFDASEVLRLMPKATTLMGVPTFYTRLLDHPGLTREATAHMRLFVSGSAPLLAETHRAFQEKTGKAILERYGMTETGMNTSNPYDGERIAGTVGFPLPGVSVRITDPATGAVLGADEIGSIEVKGPNVFKGYWKLPEKTASEFHDGFFITGDLGKIDARGYVHIVGRGKDLVITGGFNVYPKEVEGEIDALPGVLESAVIGLPHKDFGEGVTAVIVRTPGASLTEAEVHQALEGRLAKFKLPKKVFFVDELPRNTMGKVQKNILRDTYKDTYRSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHW4</accession>
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        <submittedName>
            <fullName evidence="3">Putative glycosyltransferase</fullName>
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        <lineage>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
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        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="331" mass="34418" checksum="432769F1DB45E0CA" modified="2007-12-04" version="1">MSSVPSSLTDKAQSFSVEGAVVAVAFQKKAAILIGGMGEALRIEGEAETRFTLHDGGVLDVRGDGKRLVSGGDDGRVVELSAEGEVQVRAEHKGRWIDRVALGPDGAVAYSAGKTAYVLPAKGEARSLEVASTVGGLSFAPKGLRLAVAHYGGVTLWYPNLVDAKPDLFGWKGSHLGVAFSPDGRFLVTTMQEAALHGWRVSDGGHMRMTGYPARVKSFNFSADGKWLATSGSSEVILWPFASKEGPMGKQPSMIAPSSTARVSSVACHPKDPVVAVGYEDGMVLMARISDGAEILLRAPDGSPVTATGWRADGGAVAFGTANGSAGIVTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJR4</accession>
    <name>A8IJR4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0346</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0346"/>
    <dbReference type="EnsemblBacteria" id="BAF86344">
        <property type="protein sequence ID" value="BAF86344"/>
        <property type="gene ID" value="AZC_0346"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0346"/>
    <dbReference type="eggNOG" id="COG4101">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_146491_0_0_5"/>
    <dbReference type="OMA" id="MADIACS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="149" mass="16111" checksum="0211E21893A1A3E7" modified="2007-12-04" version="1">MADIACSDDSAAPAAPNRTAGMAFPIDPGTGKEHREFFEIDEVDGWVEVAPGIEAKVLAGSIDEAARKGHLNRLVRWAPHARIDEVKVHDFYEEVFVARGSLIVAAQTPPHTPETFNAPSFACRPPGALHGPFQAGPDGCLLFETQFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKB3</accession>
    <name>A8IKB3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acetamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3884</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172404.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3884"/>
    <dbReference type="EnsemblBacteria" id="BAF89882">
        <property type="protein sequence ID" value="BAF89882"/>
        <property type="gene ID" value="AZC_3884"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3884"/>
    <dbReference type="eggNOG" id="COG2421">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032013_1_1_5"/>
    <dbReference type="OMA" id="GGNMDCR"/>
    <dbReference type="OrthoDB" id="228571at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="PTHR31891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="329" mass="35831" checksum="79245D0DD740A4F4" modified="2007-12-04" version="1">MSWLETSIMARKGVAGGKALSSHAITEATQGTYHYVYGPFAKPVLTVEPGAVVSAETHDAFEGKIRHETDSPSKILNFPYLNPQNGPIYVNGAQKGDALAVYIENIEPRGPQPRGTTVVMPEFGGLVSTDHTAMLQAPLPEVVKKLHITKEEGTRWSDKITLPYEPFIGTIGTSPEIEAISSLQPDYYGGNMDLPDVGTGAVVYLPVNTEGALLYLGDCHAAQGDGELCGVAIEHPTVTTVRIDLIKGWTLKWPRLETADVIMSIGSARPLEDAARIAYRDLIRWMAADYGFTEMDAYMLLTQAGRMRLGNMVDPKYTMGASIRKTFLV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKN6</accession>
    <name>KCY_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytidylate kinase</fullName>
            <shortName evidence="1">CK</shortName>
            <ecNumber evidence="1">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cytidine monophosphate kinase</fullName>
            <shortName evidence="1">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cmk</name>
        <name type="ordered locus">AZC_3932</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172452.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IKN6"/>
    <dbReference type="SMR" id="A8IKN6"/>
    <dbReference type="STRING" id="438753.AZC_3932"/>
    <dbReference type="EnsemblBacteria" id="BAF89930">
        <property type="protein sequence ID" value="BAF89930"/>
        <property type="gene ID" value="AZC_3932"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3932"/>
    <dbReference type="eggNOG" id="COG0283">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079959_0_1_5"/>
    <dbReference type="OMA" id="RAITWWM"/>
    <dbReference type="OrthoDB" id="776861at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0418">Kinase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000071819" description="Cytidylate kinase">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <sequence length="206" mass="21369" checksum="366F317F96A84CD6" modified="2007-12-04" version="1">MIIAIDGPAASGKGTLGKRIAGHLGLAHLDTGLLYRAVGAACLAAGKLDDEAASVEAARTLDVTTLDPESLRTGAIGEAASVVAARPGVRAALVDLQRRFAARPEGAVLDGRDIGSVICPDATVKLFVTASPEVRAERRFKELAARDPLASYEAVLADIHKRDERDSNRAAAPLVMASDAVLLDTSHLGIEESFAAALAIVERARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL56</accession>
    <name>A8IL56_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3991</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3991"/>
    <dbReference type="EnsemblBacteria" id="BAF89989">
        <property type="protein sequence ID" value="BAF89989"/>
        <property type="gene ID" value="AZC_3991"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3991"/>
    <dbReference type="eggNOG" id="COG0010">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_066809_0_0_5"/>
    <dbReference type="OMA" id="PDNMRFP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="307" mass="34550" checksum="56C5DE016F0CC183" modified="2007-12-04" version="1">MRLCVLDLDGSVAAQPLFLDRRAAGAATFVEMRDLAPQLRLTGGRRAMEAFLGRLPPPGRDADMFFYGSGDFHHLTAGLLRRVDEPVTVIHLDNHPDWLTFPPTFNCGGWVSRALRLPHVRKVITIGPCSPDLAAPDLKGANLRALADGALEVYPWRHPPSRLLSARMSAASGWTGNTIRWHNVGGAAWESFLSDLPRRIPTRAVWITLDKDVFCEPDALTNWDQGEMSLVHALVLLRRIATRHRIVGMDVCGDYSPARFRDPWRRFLAFTDHDCRRVRAADHAVINARANAQLLRLMEDIFRERPE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILP8</accession>
    <name>PCKA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="1">PCK</shortName>
            <shortName evidence="1">PEP carboxykinase</shortName>
            <shortName evidence="1">PEPCK</shortName>
            <ecNumber evidence="1">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pckA</name>
        <name type="ordered locus">AZC_4063</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="1">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172583.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ILP8"/>
    <dbReference type="SMR" id="A8ILP8"/>
    <dbReference type="STRING" id="438753.AZC_4063"/>
    <dbReference type="EnsemblBacteria" id="BAF90061">
        <property type="protein sequence ID" value="BAF90061"/>
        <property type="gene ID" value="AZC_4063"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4063"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
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    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
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    </dbReference>
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        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
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    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
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    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
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    </dbReference>
    <dbReference type="Pfam" id="PF01293">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0210">Decarboxylase</keyword>
    <keyword id="KW-0312">Gluconeogenesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-0464">Manganese</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000072373" description="Phosphoenolpyruvate carboxykinase (ATP)">
        <location>
            <begin position="1"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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            <position position="201"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
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        <ligand>
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    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <sequence length="537" mass="58634" checksum="9E17CEC9EBAD0525" modified="2007-12-04" version="1">MIETGLRNSSQGIETFGLRNLAGVHWNLTEPQLYEHAIAKGEARLAAGGALAANTGVHTGRSPKDKFVVRDATTEGEVWWDNNGSITPEQFETLYQDFLAAAEGKTLFAQDLYGGADPAHRIAARVYTEYAWHSLFIRTMLRRPAREELPGYVPELTIIDLPSFKADPARHGVRSDTIIAVNFTRRIVLIGSSSYAGEMKKSVFTFLNYLLPAKGVMPMHCSANAGKDGDVALFFGLSGTGKTTLSADPARTLLGDDEHGWSNTGVFNFEGGCYAKTIRLSKEAEPEIFAASDRFGTILENVILHEDTRVPDFDDGSLTENTRSAYPLDFIPNASPTGRAGVPKNIIMLTADAFGVMPPIARLTPAQAMYHFLSGYTAKVAGTEKGVKDPEATFSTCFGAPFMPRHPSVYGNLLRDLIAKYQVDCWLVNTGWTGGKYGVGRRMPIKVTRTLLTAALDGSLKDAAFRTDPYFGFSVPSSVPGIEPHILYPSKTWADKADFDATARKLVAMFRDNFAKFEGHVDAAVRDAQPQVRIAAE</sequence>
</entry>
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    <accession>A8IM63</accession>
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            <fullName evidence="6">Flagellar motor protein</fullName>
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    </protein>
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        <name evidence="6" type="ordered locus">AZC_0496</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169027.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0496"/>
    <dbReference type="EnsemblBacteria" id="BAF86494">
        <property type="protein sequence ID" value="BAF86494"/>
        <property type="gene ID" value="AZC_0496"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0496"/>
    <dbReference type="eggNOG" id="COG1360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016890_14_3_5"/>
    <dbReference type="OMA" id="YVSMENK"/>
    <dbReference type="OrthoDB" id="1619550at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="5">
        <location>
            <begin position="213"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="339" mass="37961" checksum="3565B4368C028472" modified="2007-12-04" version="1">MALGRRGRDRQVDYWPGFVDALSTLLLVFVFLLSVFMVTQFFLSQDISGKENVLQRLQAQIRQLTELLSLERATGQSQDSELAALRASLQATEAERDRLKAAAGPAPTGPDPSREAALAREVDMQKDVASRALAQIELLNQQIAALRRQMAALEEALNVSEKRDQESQTKIADLGKRLNVALAQRVQELSRFRSEFFGRLRDILGNRPDIRIVGDRFVFQSEVFFDRGSATPRPEALAELDKLASAILELERQIPPDINWALRIDGHTDSRPISTPQFPSNWELSAARAIAVAQYLISKGVQPRHLIAAGFGEYQPIDTGTSDESMARNRRIELKLTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM70</accession>
    <name>A8IM70_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative thiamine-phosphate pyrophosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0500</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86498.1"/>
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    <dbReference type="STRING" id="438753.AZC_0500"/>
    <dbReference type="EnsemblBacteria" id="BAF86498">
        <property type="protein sequence ID" value="BAF86498"/>
        <property type="gene ID" value="AZC_0500"/>
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    </evidence>
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    <sequence length="236" mass="23611" checksum="4B86FD3DECFE7F62" modified="2007-12-04" version="1">MPSGPASERAGCPSFACFLAEPVIMPTEPEIPRCRLMLVLPPTLSAAEAIACMGAGDVAAVIVTTPAGDETAAKAQLSELCTATQAAGVAFLLADRVELASDIGADGVHLGSYAALKRALPAVKPGGIAGIGLEGRHEAMEAGEAGADYVLFGARDGSGPIEPVVELVSWWAEVFEVPCVGVATTVEDARAIAVAGADFVALAAVPAGPDGPALVADVERAVAAVDRTVADATPKA</sequence>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="Phobius"/>
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    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF86568.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="150" mass="16428" checksum="BA23A6702D624717" modified="2007-12-04" version="1">MMDWILPKRLDNSFPGHPAVVWIFVALTLVTLGRSLFHMFAPDGGAQSVAHIPLSTYPAAASSTIIFVFALWGLSQLLMGLIYVVALIRYRGLIPLLLLLMAAEYAGRMLIATYRVLETTATPPGAVADHLTLPLALILLAFCHPRFRKG</sequence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724608" evidence="3">
        <location>
            <begin position="32"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="65"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="399" mass="42530" checksum="09DF3EED6E295242" modified="2007-12-04" version="1">MSARPAPVRFRLLAALTVLSFASGPFAPAQAAAPQAKGLTISVVRPEKQELHDTLLVTGSLLPREEIQVGPEIEGYRLTEILAEVGDTVQKGQVLARLSRDVLDTQLAQNTANAAKAKATIAQQRAALDQALAQETEANSAAERTRQLRKTGVSTQETLDERERAVKVTAAQVVAARESLKAAEADAVLVQAQRAELELKLQRTEVRAPEAGLILARDARIGAIALSTRSEPLFRIAKDGAIDLDAEVPEVALPRLAVGQTVAVTPAGFNRSVEGKVRLISAEVDKATRLGRAKIALPTQPDLRPGAFARGVVLLDRRWGLSVPQSAVMFDANGAYILVVKDGVIHERRVHTGIKTGGRVELIDGAQPDDLVVARAAGFLREGDRVTPAEAGKSVSEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IN64</accession>
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        <submittedName>
            <fullName evidence="10">MiaB-like tRNA modifying enzyme</fullName>
        </submittedName>
    </protein>
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        <name evidence="10" type="ordered locus">AZC_3709</name>
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    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172232.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3709"/>
    <dbReference type="EnsemblBacteria" id="BAF89707">
        <property type="protein sequence ID" value="BAF89707"/>
        <property type="gene ID" value="AZC_3709"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3709"/>
    <dbReference type="eggNOG" id="COG0621">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018697_1_1_5"/>
    <dbReference type="OMA" id="HFHIPLQ"/>
    <dbReference type="OrthoDB" id="397139at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006467">
        <property type="entry name" value="MiaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01579">
        <property type="entry name" value="MiaB-like-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="8">
        <location>
            <begin position="10"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="144"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="429" mass="46395" checksum="84444D3E10C12F91" modified="2007-12-04" version="1">MGQAGARETEGVEVVTFGCRLNTLDGAEIQRAATAAGLTRTVIVNSCAVTAEAVRQARQSIRRLKRADPALKVVVTGCAAQTEPQTFATMPEVDRVVGNGAKGAVETWAEARAAFDFGVSAEEKVKVDDIFAVRETALHMVDGMDGRTRAFVQVQNGCDHRCTFCIIPYGRGASRSVPMGDVVAHIRALAEGGQKEVVLTGVDLTSYGADLPGAPTLGRLVRAILRQVPELERLRLSSIDSVEADADLLRALAEEERLMPHLHLSLQSGDDMILKRMKRRHSRAQVIALVEEMRRLRPDLVLGADLIAGFPTETEAMFRNSLSIVDACGLSFLHVFPFSARAGTPAARMPPVPGDVVDARARRLREKGEEALRRHLAAEIGRRHPVLVERGGIGRTPYFTPVRLHRAAQPGAVIDLRIAGHDGARLVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IN91</accession>
    <name>A8IN91_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3719</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS1 family.</text>
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    <keyword evidence="3" id="KW-0677">Repeat</keyword>
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    <keyword evidence="5 7" id="KW-0689">Ribosomal protein</keyword>
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        <location>
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            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
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        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF89718">
        <property type="protein sequence ID" value="BAF89718"/>
        <property type="gene ID" value="AZC_3720"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
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    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="7">
        <location>
            <begin position="89"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="505" mass="54116" checksum="FAA91FD3254AA26B" modified="2007-12-04" version="1">MTSATAREKGRGLVRARVARAGRSTCAMLTLVGLLTGCAGVDLDRSTVPLTQSKLSAADTADMSPAQRREHERLVASYGGAYDDPELKALIQQVVERLVAASERPDLKYRVTVLNSPAINAFALPDGSLYVTRGLLALANDTSEMSSVLAHEMAHVIARHASIREDQVKQAVLVSRVISDVVADQNMGALAMQKSRQTLATFSRGQELEADAIGVGIAARAGFDPYGASRFLTDMGKQASLRTSAFGGASSTTPDMDFLATHPATPDRISIAIANAREYAAPGAGERDKAAYLAAIDGMVYGDDPKEGYVRGRNFFHPKLGFTFTAPEGFSLENTSQAVLGATANGSEALRLDAVRVSGDQSLGQYLASGWIDGVEINSVESLSVNGFTAATAVARGDQWSFRMFAIRFGSDVYRLIFAARNLTPELDKQFRAAASTFRRVASDEAQSVKPLRIRIVTVGIGDTVEKMAGRMQVADHPMERFLILNGLDRDAKLAYGSKVKIVVE</sequence>
</entry>
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        <name evidence="1" type="ordered locus">AZC_3804</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3804"/>
    <dbReference type="EnsemblBacteria" id="BAF89802">
        <property type="protein sequence ID" value="BAF89802"/>
        <property type="gene ID" value="AZC_3804"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3804"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_3076336_0_0_5"/>
    <dbReference type="OMA" id="RYQHERQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="52" mass="5737" checksum="D41997277E6A68AF" modified="2007-12-04" version="1">MRLGSLAALMPKEPVGRYQHERQGELIHLGIKKIARFAGVGHRITGSRRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPD6</accession>
    <name>A8IPD6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trbJ</name>
        <name evidence="3" type="ordered locus">AZC_3862</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3862"/>
    <dbReference type="EnsemblBacteria" id="BAF89860">
        <property type="protein sequence ID" value="BAF89860"/>
        <property type="gene ID" value="AZC_3862"/>
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    <dbReference type="OrthoDB" id="1557327at2"/>
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        <property type="component" value="Chromosome"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723731" evidence="2">
        <location>
            <begin position="24"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="250" mass="26659" checksum="6590BE55B662BCE3" modified="2007-12-04" version="1">MTLFRPRALTVAVVLLTAPLALAPVLFPSAQALTVYDPWNYAQNMMSAARALEQINNQITSLQNEAQMLINQARNLASLPHSSLQQIQQSVQRTQQLLGQAQSIAFDVGQIDQAFQQRYGNIPLSASDADLVAGARSRWQTTVGGLQDALRVQAGVVGNVDANKAEMATLVGQSQGATGALQATQAGNQLLALQSQQLSDLIAVMSANGRAAALSEAERATAAEQGREQRRRFLTPGAGYQAGNARMFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPH4</accession>
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    <protein>
        <submittedName>
            <fullName evidence="3">Hypothetical transmembrane protein</fullName>
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    <gene>
        <name evidence="3" type="ordered locus">AZC_0622</name>
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    <organism evidence="3 4">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the virb1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0622"/>
    <dbReference type="CAZy" id="GH23">
        <property type="family name" value="Glycoside Hydrolase Family 23"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86620">
        <property type="protein sequence ID" value="BAF86620"/>
        <property type="gene ID" value="AZC_0622"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0622"/>
    <dbReference type="eggNOG" id="COG0741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_063182_1_0_5"/>
    <dbReference type="OMA" id="HAGPNNN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="13"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="179" mass="20055" checksum="8FE2E0258D7BF4DE" modified="2007-12-04" version="1">MQPDACEKELVRAAAKYKIPLPILYAVGLTETGVNGKMHPFTLYIEGKDYQPKTLTEALARFKEANDRGVKLIDIGCMQANFYWHRAEFKSLEAMFDPRENVEQAARFLSELKQRHGSWTMAAARYNAGPNNNVAQHRYVCRVMKNLVAVGVGAWTPSAKAFCDAPPPSPQQAQVQQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPJ9</accession>
    <name>A8IPJ9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Flagellar basal-body rod protein FlgG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Distal rod protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">flgG</name>
        <name evidence="10" type="ordered locus">AZC_0634</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="5 7">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169165.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0634"/>
    <dbReference type="EnsemblBacteria" id="BAF86632">
        <property type="protein sequence ID" value="BAF86632"/>
        <property type="gene ID" value="AZC_0634"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0634"/>
    <dbReference type="eggNOG" id="COG4786">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013687_0_1_5"/>
    <dbReference type="OMA" id="MIQGDGF"/>
    <dbReference type="OrthoDB" id="1488472at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009426">
        <property type="term" value="C:bacterial-type flagellum basal body, distal rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012834">
        <property type="entry name" value="FlgG_G_neg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02488">
        <property type="entry name" value="flgG_G_neg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="8">
        <location>
            <begin position="6"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="9">
        <location>
            <begin position="183"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="262" mass="27934" checksum="27920C219C9E7037" modified="2007-12-04" version="1">MRALAIAATGMNAQQTNVEVIANNIANINTTGFKRARAEFSDLLYQSERTQGIPNRDGGQAIPEGAMLGLGVRTVGIRNLHTQGPLTQTGNTLDLAVNGRGMFEITTPDGQTVYTRAGSFNRSATGQLVTSDGYVINPAIQFPNNATEIQVNESGQVYATIPNQTNPQLLGQLTLVNFANESGMEPLGNNLYRETLASGQPIVGVAGDVGFGKIQQGYLEASNVDPVKEITELIAAQRSYEMNSKVIQAADEMSKTVSTGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPU5</accession>
    <name>A8IPU5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0697</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169228.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0697"/>
    <dbReference type="EnsemblBacteria" id="BAF86695">
        <property type="protein sequence ID" value="BAF86695"/>
        <property type="gene ID" value="AZC_0697"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0697"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_2_5"/>
    <dbReference type="OMA" id="FDSMRIF"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="303" mass="32661" checksum="02313C7180BC3F6E" modified="2007-12-04" version="1">MLKLDGVAAFVAVADAGSISEAARRLGLAKSVVSERLAELERLLGARLMQRSTRRLALTEAGTAFLTRGRRLLREAEEAVAEIAEQKSLLAGPLRVSAPVSFGTLHLGRALHPFLAAHPGIELTLELDDRFVDVVTDGFDLVIRHGQVHDTRLAARRLATSRRFLVAAPAYLEAHEAPASLDALSAHRAILYANRETDWRFETPSGAVAVRPRPGLRVNNGVMMRGAAVAGLGLALLPTFLCHEELAAGTLKVVDVGVPAEGAQLHAAYPLDRSASAKLRALIEHLRRAFGSPPFWEKGLRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQA7</accession>
    <name>A8IQA7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0762</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169293.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0762"/>
    <dbReference type="EnsemblBacteria" id="BAF86760">
        <property type="protein sequence ID" value="BAF86760"/>
        <property type="gene ID" value="AZC_0762"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0762"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="IFQSHAL"/>
    <dbReference type="OrthoDB" id="1832232at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005890">
        <property type="entry name" value="NO3_transporter_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01184">
        <property type="entry name" value="ntrCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="295" mass="32870" checksum="798CAD9F13AF11DC" modified="2007-12-04" version="1">MGERYLSIEGIARRFPSAKGETTVFEDLWFSMNKGEFACIIGHSGCGKTTVLNILSGLEAPDDGAVIVDGRAIEGPSLDRAVIFQSHALLPWKSVLGNVAYAVASRHRDWPRDRVRAHAERFVELVGLKGSEHKKPAELSGGMKQRVGIARALSIEPKMLLMDEPFSALDALTRGTLQDEVRRICLESGQTVFMITHDVDEAIYLADRIVLMTNGPQACIAEIVENPLPRERRRLDLHKQTDFYAVRNHLIDFLVERSRTFKNSLPAGYDRRRPSVVRPSLAGEPVLSATRRSVV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-02-01" modified="2022-08-03" version="105" xmlns="http://uniprot.org/uniprot">
    <accession>P33982</accession>
    <accession>A8IKL9</accession>
    <name>Y3926_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Probable ABC transporter ATP-binding protein AZC_3926</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>ORF1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_3926</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1993" name="Mol. Plant Microbe Interact." volume="6" first="238" last="252">
            <title>Azorhizobium caulinodans nitrogen fixation (nif/fix) gene regulation: mutagenesis of the nifA -24/-12 promoter element, characterization of a ntrA(rpoN) gene, and derivation of a model.</title>
            <authorList>
                <person name="Stigter J."/>
                <person name="Schneider M."/>
                <person name="de Bruijn F.J."/>
            </authorList>
            <dbReference type="PubMed" id="8471796"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="X69959">
        <property type="protein sequence ID" value="CAA49581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S33579">
        <property type="entry name" value="S33579"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P33982"/>
    <dbReference type="SMR" id="P33982"/>
    <dbReference type="STRING" id="438753.AZC_3926"/>
    <dbReference type="EnsemblBacteria" id="BAF89924">
        <property type="protein sequence ID" value="BAF89924"/>
        <property type="gene ID" value="AZC_3926"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3926"/>
    <dbReference type="eggNOG" id="COG1137">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_5"/>
    <dbReference type="OMA" id="LPMYQRA"/>
    <dbReference type="OrthoDB" id="1220708at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000093177" description="Probable ABC transporter ATP-binding protein AZC_3926">
        <location>
            <begin position="1"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="45"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="77"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="281" mass="30620" checksum="7B589FDD1074BC45" modified="1994-02-01" version="1">MNVLSMFGRNATRETSSPAATAGRYADEGDWEGDDHQPATAEGSLAAFGLAKSYGGRKVVRDVSLDVRRGEAVGLLGPNGAGKTTVFYMITGLVKADQGRIELDGHDVTPMPMYRRARLGIGYLPQEASIFRGLSVEDNIGAVLEITEPNRKRRAEELDALLEEFKITHVRKSPSIALSGGERRRVEIARALASRPAFMLLDEPFAGIDPIAVGDIQALVRHLTTRGIGVLITDHNVRETLGLIDRAYIIHSGTVLMEGDPESIVASPDVRRLYLGEEFRL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2001-08-29" modified="2022-05-25" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>Q43971</accession>
    <accession>A8IBJ6</accession>
    <name>HFQ_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein Hfq</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hfq</name>
        <name type="synonym">nfrA</name>
        <name type="ordered locus">AZC_3080</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1994" name="Proc. Natl. Acad. Sci. U.S.A." volume="91" first="4663" last="4667">
            <title>The expression of nifA in Azorhizobium caulinodans requires a gene product homologous to Escherichia coli HF-I, an RNA-binding protein involved in the replication of phage Q beta RNA.</title>
            <authorList>
                <person name="Kaminski P.A."/>
                <person name="Desnoues N."/>
                <person name="Elmerich C."/>
            </authorList>
            <dbReference type="PubMed" id="8197116"/>
            <dbReference type="DOI" id="10.1073/pnas.91.11.4663"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <scope>FUNCTION</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Seems to be involved in the regulation of NifA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Hfq family.</text>
    </comment>
    <dbReference type="EMBL" id="X76450">
        <property type="protein sequence ID" value="CAA53989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="I39519">
        <property type="entry name" value="I39519"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171604.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q43971"/>
    <dbReference type="SMR" id="Q43971"/>
    <dbReference type="STRING" id="438753.AZC_3080"/>
    <dbReference type="EnsemblBacteria" id="BAF89078">
        <property type="protein sequence ID" value="BAF89078"/>
        <property type="gene ID" value="AZC_3080"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3080"/>
    <dbReference type="eggNOG" id="COG1923">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_113688_0_0_5"/>
    <dbReference type="OMA" id="QQMVYKH"/>
    <dbReference type="OrthoDB" id="1989988at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01716">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00436">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005001">
        <property type="entry name" value="Hfq"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34772">
        <property type="entry name" value="PTHR34772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17209">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02383">
        <property type="entry name" value="Hfq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_0000095613" description="RNA-binding protein Hfq">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000269" key="2">
        <source>
            <dbReference type="PubMed" id="8197116"/>
        </source>
    </evidence>
    <sequence length="85" mass="9621" checksum="CECEC3380DD8C94B" modified="1996-11-01" version="1">MAAERTQNLQDTFLNHVRKSKTPLTIFLVNGVKLQGVVTWFDNFCVLLRRDGHSQLVYKHAISTIMPGHPVQLFDPTDEVASEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQ83</accession>
    <name>A8HQ83_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4084"/>
    <dbReference type="EnsemblBacteria" id="BAF90082">
        <property type="protein sequence ID" value="BAF90082"/>
        <property type="gene ID" value="AZC_4084"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4084"/>
    <dbReference type="eggNOG" id="COG3911">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114480_0_0_5"/>
    <dbReference type="OMA" id="TPPWPEI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="9"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="181" mass="19568" checksum="475E82CC36E7C2EE" modified="2007-12-04" version="1">MRTTMGRLVLISGCSGGGKSTLLEALAALGHEVVPEPGRRVIAAFHAGQGGALPWDDLGAFARHALALARSDRAAALARPGLVFFDRGTIDAAAALAQAEGVPLRDSLGPERHYHRRVFLTPPWQEIYVRDAERRHDLAAAEEEYERLRTILPALGYEAVILPRTDVGARVRFVLDTLADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRW7</accession>
    <name>A8HRW7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amide-urea binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4106</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4106"/>
    <dbReference type="EnsemblBacteria" id="BAF90104">
        <property type="protein sequence ID" value="BAF90104"/>
        <property type="gene ID" value="AZC_4106"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4106"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027128_1_1_5"/>
    <dbReference type="OMA" id="LWSKTRI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd06355">
        <property type="entry name" value="PBP1_FmdD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017777">
        <property type="entry name" value="ABC_urea-bd_UrtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03407">
        <property type="entry name" value="urea_ABC_UrtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="452" mass="49191" checksum="6D534ADA789FCFA7" modified="2007-12-04" version="1">MRSMAASLVNLLGPKFGPRFSVEGMGMSSSDDRQDKMSATRRGVLKGLAALPIASAVPAASFLSTPARADVPPTSAVNTTGLAVTDTEVTVGILHSVTGTMAISETGSVQAEKLAIDQINAAGGILGRKIKFIQEDGASDWPTFAEKAKKLLVQDKCASVFGCWTSASRKAVLPVFEQYNGMLYYPTFYEGLEQSKNVIYTGQEATQQIIAGLNWVVKERGAQTFYLLGSDYIWPRTSNKIARKHIENFLKLKVVGEEYFPLGHTQFNSAINKIKLTKPDVIYAIIVGGSNVAFYKQLKAAGIDLSKQTLLTISVTEDEILGIGGENIAGAFACMKYFQSLNNPNNKAFVEAFKKTYGDKIVIGDVTQAAYLGPWLWKLTVEKAGSFDIDKVAAASPGVAFDKAPEGYVRIHENHHLWSKTRVGKARVDGQYDVVYETSELVEPDPFPKGYQ</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS10</accession>
    <name>ATPB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit beta</fullName>
            <ecNumber evidence="1">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpD</name>
        <name type="ordered locus">AZC_4125</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172645.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HS10"/>
    <dbReference type="SMR" id="A8HS10"/>
    <dbReference type="STRING" id="438753.AZC_4125"/>
    <dbReference type="EnsemblBacteria" id="BAF90123">
        <property type="protein sequence ID" value="BAF90123"/>
        <property type="gene ID" value="AZC_4125"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4125"/>
    <dbReference type="eggNOG" id="COG0055">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022398_0_2_5"/>
    <dbReference type="OMA" id="GFNMIMD"/>
    <dbReference type="OrthoDB" id="430176at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0139">CF(1)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-1278">Translocase</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000339476" description="ATP synthase subunit beta">
        <location>
            <begin position="1"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="151"/>
            <end position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <sequence length="478" mass="51105" checksum="8EFC94B708A64D0F" modified="2007-12-04" version="1">MANKSGRITQVIGAVVDVQFDSHLPEILNALETTNQGNRLVLEVAQHLGENTVRTIAMDSTEGLVRGQAVEDTGGPIMVPVGEATLGRIMNVIGEAVDELGPVVGEAKRAIHQQAPSYSEQSTEAEMLVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNIAKAHGGYSVFAGVGERTREGNDLYHEMIESKVNVDPHENNGSSAGSKCALVYGQMNEPPGARARVALTGLTVAEHFRDQGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTTKGSITSVQAIYVPADDLTDPAPAASFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRILSPLVIGEEHYNVARQVQQTLQRYKALQDIIAILGMDELSEEDKLTVARARKIERFLSQPFHVAEVFTGSPGKLVDLADTIKGFKGLVEGKYDHLPEQAFYMVGTIEEAIEKGKKLAAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSE0</accession>
    <name>A8HSE0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase-2</fullName>
            <ecNumber evidence="5">3.5.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ribA</name>
        <name evidence="7" type="ordered locus">AZC_4172</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:23704"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase II family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.25" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172692.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4172"/>
    <dbReference type="EnsemblBacteria" id="BAF90170">
        <property type="protein sequence ID" value="BAF90170"/>
        <property type="gene ID" value="AZC_4172"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4172"/>
    <dbReference type="eggNOG" id="COG0807">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020273_1_2_5"/>
    <dbReference type="OMA" id="KMRAYSL"/>
    <dbReference type="OrthoDB" id="900513at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003935">
        <property type="term" value="F:GTP cyclohydrolase II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00641">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00179">
        <property type="entry name" value="RibA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000926">
        <property type="entry name" value="RibA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="6">
        <location>
            <begin position="175"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="214"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="257"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="370" mass="39282" checksum="C04620B59CA1C4B9" modified="2007-12-04" version="1">MSPTVEIPGLSFGATQTAVERAIAELRSGRPVVLEDQGQELLAIGVEALDANIAQGFAAVGQGLTRLVLPAPRLTRIGAPRSSAGTIALPDVDLARIETLALRIDGRIDAPVALATTLDVAVLHLLGFALVLPAAIVAPVSASALPHLMRVTKTEIDDFRASQVRSLRVVGRAPVPLEGALDTEFVVFRGGEGLRDQVAIVVGKPDLSGPVPVRLHSACLTGDLFGSLKCDCGDQLRDTVQRMARSSGGILLYLDQEGRGNGIANKMKAYHLQSQGFDTYEADAALGFDLDQRRFDFAAEMLRQLGVTAVEILTNNPQKIAALKAAGIEVAGDRRVLGRPTAENVRYLASKRDRAGHYIDFDALAARASD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT29</accession>
    <name>GCSPA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable glycine dehydrogenase (decarboxylating) subunit 1</fullName>
            <ecNumber evidence="1">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine cleavage system P-protein subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glycine decarboxylase subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Glycine dehydrogenase (aminomethyl-transferring) subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gcvPA</name>
        <name type="ordered locus">AZC_4248</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvP family. N-terminal subunit subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172768.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HT29"/>
    <dbReference type="SMR" id="A8HT29"/>
    <dbReference type="STRING" id="438753.AZC_4248"/>
    <dbReference type="EnsemblBacteria" id="BAF90246">
        <property type="protein sequence ID" value="BAF90246"/>
        <property type="gene ID" value="AZC_4248"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4248"/>
    <dbReference type="eggNOG" id="COG0403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004620_0_2_5"/>
    <dbReference type="OMA" id="MYDGASA"/>
    <dbReference type="OrthoDB" id="870147at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00712">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
        <property type="entry name" value="PTHR42806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006815">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000072767" description="Probable glycine dehydrogenase (decarboxylating) subunit 1">
        <location>
            <begin position="1"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00712"/>
        </source>
    </evidence>
    <sequence length="447" mass="47277" checksum="D776DEC3602BF231" modified="2007-12-04" version="1">MRYLPLTPEDRTEMLARIGAPSVDALFADIPAAKLDPALADLPAHKTELSVERTLGALSAQNVPAGSVPFFVGAGAYRHHVPATVDHLIQRSEFLTSYTPYQPEIAQGTLQYLFEFQTQVGELTGMEVANASMYDGSTAAAEAVLMAHRVTKRRKAVVAGNVHPHYRETIATLSLYADDAVVALSPVPQGGEDILSAIDGETSCVVVQSPDVFGNIVDLKPIAEKAHAAGALLIAVFTEVVSLGLIEPPGAQGADIVVGEGQSIGNPLTFGGPYVGLFATRQKYVRQMPGRLAGETVDASGKRGFVLTLSTREQHIRREKATSNICTNSGLCALAFTIHLTLLGETGLRKLARLNHANACKLADKLAAVPGVQVLNSAFFNEFTLRVPGKAVDVIEKLAAKGVLGGVPYARLAPKAGLDDLILVAATEINTDEDRAAYAAALKEVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT46</accession>
    <name>A8HT46_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rluD</name>
        <name evidence="6" type="ordered locus">AZC_4254</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4254"/>
    <dbReference type="EnsemblBacteria" id="BAF90252">
        <property type="protein sequence ID" value="BAF90252"/>
        <property type="gene ID" value="AZC_4254"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4254"/>
    <dbReference type="eggNOG" id="COG0564">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016902_4_1_5"/>
    <dbReference type="OMA" id="AHPSPGW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="42"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="354" mass="37864" checksum="5523E8D0BAFEA014" modified="2007-12-04" version="1">MGQPLRNETLDDDDLLDLPIGDASEDDGTAHVLTVGPEDAGLRADRFLAARLPDLSRTRLQKLVADGRVSVGGRVVGDPAERVNAGDEWTVRVPAPEPAAPVPEKMDLSIAYEDDFLIVVDKPAGLVVHPAPGNWSGTLVNGLLAHCGASLSGIGGVKRPGIVHRLDKDTSGLLVVAKTDAAHAGLAAQFADHGRTGPLERAYYAFVWGVPDQRGTVDAPIDRHPTHRQKMAVRQSGREAITHWERLEVFAGADGAPLASLIECQLETGRTHQIRVHLAHVGHPLLGDEVYGQGFRTKASRLPEGARALLAALGRQALHAARLGFAHPVTDEELLFESPLPEDLARLRDALALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTQ5</accession>
    <name>A8HTQ5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0861</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Ussery D.W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        </citation>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </source>
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        <location>
            <begin position="94"/>
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        <source>
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    <sequence length="296" mass="32038" checksum="BF18DCF8D429385E" modified="2007-12-04" version="1">MSDDLIAAAKRRFTDLLPQSWRRDLTLVPVVRLSGAIGMNSPFRQSLTLAATARLLDRAFAVKRAPAVALVINSPGGSPVQSNLIFKRIRALAEEKNKRVFAFVEDVAASGGYMLACAADEIYADPSSIVGSIGVVSAGFGFNDMLSRIGVERRVHTAGTRKVMLDPFQPERAEDVDRLLAIQREVHASFRDLVRSRRGALLKGEEDDLFSGEFWVGAQALPMGLIDGLGDLRSVLRERFGTDVRTPLIAPSGNWFTRRANGIGAQIGLDGGIGAGFAQGLADVAEERALWARYGL</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
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            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <text evidence="3">Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.</text>
    </comment>
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            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
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            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
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        </reaction>
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    <comment type="pathway">
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    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
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        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0718">Serine biosynthesis</keyword>
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        <location>
            <begin position="456"/>
            <end position="528"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00000646"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001878"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003800"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005216"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005854"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021582"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363003"/>
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    </evidence>
    <evidence type="ECO:0000259" key="10">
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            <dbReference type="PROSITE" id="PS51671"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
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            <dbReference type="EMBL" id="BAF86983.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="528" mass="55710" checksum="348C6724B7787002" modified="2007-12-04" version="1">MAPRVLISDKLSDAAVQIFKDRGVEVDFRPDLGKDKDKLAEVIGDYDGLAIRSATKVTPKILEKASRLKVIGRAGIGVDNVDIPAATARGVIVMNTPFGNSITTAEHAIAMMFALARQIPQADASTQAGKWEKNRFMGVELTAKTLGIIGCGNIGSIVAERGIGLKMKVIAFDPFLSPERALALGVEKVELDELLARADVITLHTPLTEKTKNVLSAENIARAKPGVRIINCARGGLVDEVALRAALDSGHVAGAAFDVFSVEPAETNVLFGHPNVVCTPHLGAATTEAQENVALQVAEQMSDYLLAGAISNAVNFPSITAEEAPRLKPFIALAEKLGSFAGQLTDTDIKTVRITYEGAVAEQKVKALTSAAIAGLLRPVLADVNVVSAPSVAKERGIVIEETTRDAVGDYDSLVTLSVVADDFERHVAGTVFADGQPRIVDIKGIKVDAGFAPNMLYVTNEDKPGFIGRFASLLGDAGVNIATFALGRDHPGGDAIALVEVDGPVPADVLGKVSALPHVRQVKQLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV80</accession>
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        <name evidence="8" type="ordered locus">AZC_4284</name>
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    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="8 9" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_4284"/>
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        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Alkb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
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        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16557">
        <property type="entry name" value="PTHR16557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="163"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="266" mass="29076" checksum="007F78CDA14E9126" modified="2007-12-04" version="1">MGPQRPLRPAVPRSLGAPRAGAFHNRRPVGPSARAPAFLDAGKHPVAPSGRQTIREDHLATPHPMEIAPDALWWPGRLDRPAQEALVEEVREVLRAAPLFQPAMPRTGKPLSVRMSNCGPLGWVADASGYRYQPFHPETREPWPPMPETLLRLWADFSGSAVPPEACLVNWYAPDARMGLHQDRDEADFSAPVLSVSLGDTAVFRIGGEARTDSTRSIRLESGDVLRLGGRSRLAFHGVDRILPGTSTLLGVEGRINLTLRRVTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVC7</accession>
    <name>A8HVC7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Tryptophanyl-tRNA synthetase</fullName>
            <shortName evidence="8">TrpRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">trpS</name>
        <name evidence="10" type="ordered locus">AZC_4301</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of tryptophan to tRNA(Trp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp)</text>
            <dbReference type="Rhea" id="RHEA:24080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9671"/>
            <dbReference type="Rhea" id="RHEA-COMP:9705"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78535"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4301"/>
    <dbReference type="EnsemblBacteria" id="BAF90299">
        <property type="protein sequence ID" value="BAF90299"/>
        <property type="gene ID" value="AZC_4301"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4301"/>
    <dbReference type="eggNOG" id="COG0180">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029244_1_4_5"/>
    <dbReference type="OMA" id="GWGQFKP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00140_B">
        <property type="entry name" value="Trp_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024109">
        <property type="entry name" value="Trp-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="26"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="219"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="25"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="33"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>L-tryptophan</name>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="161"/>
            <end position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="219"/>
            <end position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF90299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="357" mass="38974" checksum="9FD7C64B34E837B7" modified="2007-12-04" version="1">MAVFAPSLRRSPMAAVAERVFSGVQPTGNLHLGNYLGAIKRFVALQESHECIYCVVDLHAITVWQDPAELKRHIREVTAAFIACGIDPKRHIVFNQSQVSGHAELAWVFNCVARMGWLNRMTQFKEKAGKDRENVSLGLFAYPSLMAADILLYRATHVPVGEDQKQHLELTRDIAQKFNTDFGPSIAENGFGEGYFPLTEPLIAGPATRVMSLRDGSKKMSKSDASDMSRINLTDDADAIASKVRKAKTDPEPLPSEEEGLKARPEADNLVGIYAALSDTTKQAVLTEYGGGQFSTFKMALVDLAVAKLGPIGGEMQRLMGDVSAIDAILKDGADRARVIADQTIRDVKDIVGMVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVT3</accession>
    <name>A8HVT3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HyqI</fullName>
            <ecNumber evidence="7">1.12.5.1</ecNumber>
        </submittedName>
        <submittedName>
            <fullName evidence="8">NADH ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hyqI</name>
        <name evidence="8" type="ordered locus">AZC_4355</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="8">ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="8">ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7" key="5">
        <citation type="journal article" date="2009" name="PLoS ONE" volume="4" first="E4695" last="E4695">
            <title>A novel endo-hydrogenase activity recycles hydrogen produced by nitrogen fixation.</title>
            <authorList>
                <person name="Ng G."/>
                <person name="Tom C.G."/>
                <person name="Park A.S."/>
                <person name="Zenad L."/>
                <person name="Ludwig R.A."/>
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            <dbReference type="DOI" id="10.1371/journal.pone.0004695"/>
        </citation>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="7">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        </source>
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    <reference evidence="9" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
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        <property type="entry name" value="MetI-like"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="94"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="297" mass="31710" checksum="92A2E89970C85DBD" modified="2007-12-04" version="1">MTAISSEPARRRASGGLTATLKHAQYVISDNPVTGLAFFMLLVLVVAALIGPFIVPYDPLASDTVNALKPPTAAHWFGTDQLGRDIFSRVIVATRLDLAIAVFSVALVFAAGGIAGIAAGFFGGWTDRIVGRICDTIMAFPLFVLAMGIVAALGNTVTNIVIATAIINFPLYARVARSEAAIRRQAGFIQAARLTGNSEWRILLTQILPNILPIMMVQMSLTMGYAILNAAGLSFIGLGVRPPTAEWGIMVAEGATFIVSGEWWIALFPGLALMFAVFCFNLLGDGLRDIVDPQRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170078.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1550"/>
    <dbReference type="EnsemblBacteria" id="BAF87548">
        <property type="protein sequence ID" value="BAF87548"/>
        <property type="gene ID" value="AZC_1550"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1550"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_3_5"/>
    <dbReference type="OMA" id="WMIERPQ"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Amidase_CS"/>
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        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
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        <property type="entry name" value="AS_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="4">
        <location>
            <begin position="25"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="470" mass="48629" checksum="55924069BC208226" modified="2007-12-04" version="1">MTDIATLSLTEIAAAIANRQVSSREATQACLDRIADWQPHLNAFIALEPDEALKAADAADAALAKGESAGPLHGVPLAHKDMFYEAGKVCTCGTEIRRSFVPDTSSTALARIKAAGTVRLGTLHMVEFAFGPTGHNVHYGDCHNPWNVAHAPGGSSSGSGAAVAARLTFAALGSDTGGSVRMPAHFCGVTGLKTTVGRVSRFGAMPLSHSLDTVGTLTRTAEDAALLLGLMAGADPADPTTIGGDLPDYLAATKGGLAGLTIGIPDSFYVDDISSDTAAAMDATIATLVREGANVVRVSLPDQRQLSAAAQVLLGVEASAIHLPWLRERPQDYGAQVRARVENGHAFSGVAYLEALRWRGPALAAHLAAVTEVDAVLAPVCPAPSPTLAETDVGGSFNAEAVIQGITRFTRPVNYLGLPALVVPVARAASGLPVGFQFIGRPFAEDVLLRIGAGFQRATDFHLATPELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYG0</accession>
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        <submittedName>
            <fullName evidence="4">Histone-like bacterial DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1611</name>
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    <organism evidence="4 5">
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial histone-like protein family.</text>
    </comment>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4595"/>
    <dbReference type="EnsemblBacteria" id="BAF90593">
        <property type="protein sequence ID" value="BAF90593"/>
        <property type="gene ID" value="AZC_4595"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4595"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="EamA_dom"/>
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        <property type="match status" value="2"/>
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        <location>
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    <feature type="domain" description="EamA" evidence="2">
        <location>
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        <location>
            <begin position="159"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="307" mass="33005" checksum="23CD2E6F4B20C4F8" modified="2007-12-04" version="1">MRPAMSAATKPASRRLFGILLMCLAVSTFAISDAMAKWLGAHINVFMVVWARYVVHFVIALVVFNPWTVPGLLSTRRPVLQVTRSALLFGCTILNFTALQFLQLDQTVSIMFSAPFFVALFAGPMLGEWVGARHWAAISAGFAGILLVAQPGAGGIHPAALLSLFSAGCYALYAILTRMLADTDKTPTTLFYTSLVGSVVASLPLPFAWETPQEPAVLVVLLLIGLVAGGGHMLLIIAHRHAPAAVLAPFLYVQIIGMIILGWALFHQVPSLWTLAGAAIVIASGVYLLLNERRERARETLEATLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Yamada M."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1415"/>
    <dbReference type="EnsemblBacteria" id="BAF87413">
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        <property type="gene ID" value="AZC_1415"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1415"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_3_0_5"/>
    <dbReference type="OMA" id="NYGHIGD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
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    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
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    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55103"/>
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    </dbReference>
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        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="75"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="504" mass="53563" checksum="93A31EEE56B51D84" modified="2007-12-04" version="1">MMAQAVSNIRRPRARKTGPLRREEDMSAQARIDGVPIGAPSLDIIMARLAAIVGDRASAAPGVRADHGRSEAYHAARPPDVVVFPETTAEVQAIVNLCRELDLPLVPFGAGTSLEGNAAALHGGVCLDMGRMNQMLEIHAEDMDVRVQPGITRKQLNAQLRDTGLFFPIDPGADASIGGMTSTRASGTMAVRYGTMKDNVLALEVVLADGRAIRTARRAKKSAAGYDLTRLFVGAEGTLGVITEITLKLHPQPEAISSAVCAFPDLKAAVDTAIGVIQSGVPVARIELLDAVMMRGMNLHSRLGLPEVPHLFFEFHGSSAYVTEQAETAQAIAADNGGQGFQWAVTPEERTRLWHARDNTLYAGLALRPGAKAMITDVCVPISRLADCLVDTAADLVECGLVAPVVGHVGDGNFHLLVLIDPQDPEELARAKAFNERLVRRAIALDGTCTGEHGIGMGKMDFLALELGEAVDAMRLLKGALDPHGILNPGKIFKPHPPTQGSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2A1</accession>
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            <fullName evidence="10">Polar amino acid uptake family ABC transporter permease protein 2</fullName>
        </submittedName>
    </protein>
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        <name evidence="10" type="ordered locus">AZC_1838</name>
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    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170366.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1838"/>
    <dbReference type="EnsemblBacteria" id="BAF87836">
        <property type="protein sequence ID" value="BAF87836"/>
        <property type="gene ID" value="AZC_1838"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1838"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_1_5"/>
    <dbReference type="OMA" id="KRMLPPW"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="77"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="81"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="290" mass="31924" checksum="47158944DFE4A807" modified="2007-12-04" version="1">MSGAPSSTGTLPASPLPVLLPFRLGERRRRFPPWRITLLHAVGIVGIGLVVAGGAHAQGAPGQLSAFGVIWKWFPLLMWGFGFNILISVLSMALGTVAGLGLGLAAISQSAPLRQTAWGATQFFRNAPWLVLLFFAMFMIPFQFTILGKTIPFPDWVKAVIGFALPVMANMAEIVRGAVKSLPSGQWEAAESLAFSRRQTLWMIILPQCVKRMLPPWMNLYTLVTMATVQASIVGVTEMLTLIAQVHAAEGGRPDLLAPLYGFAMLCFFVYCYPIERFTLYLERRFQLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2B9</accession>
    <name>A8I2B9_AZOC5</name>
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        <recommendedName>
            <fullName evidence="7 16">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="6 16">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">AZC_1848</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
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            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
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            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
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            <dbReference type="ChEBI" id="CHEBI:58349"/>
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            <dbReference type="EC" id="1.1.1.3"/>
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    <comment type="pathway">
        <text evidence="3 16">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
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    <keyword evidence="16" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="9 16" id="KW-0412">Isoleucine biosynthesis</keyword>
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    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="349"/>
            <end position="433"/>
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    <feature type="active site" description="Proton donor" evidence="14">
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            <end position="16"/>
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    </evidence>
    <evidence type="ECO:0000313" key="20">
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </source>
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        <ligand>
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    </evidence>
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    </evidence>
    <sequence length="285" mass="31297" checksum="8B8343FDF98ACA15" modified="2007-12-04" version="1">MSLQTLEATHPPVLPAAAPSPAIELENVTRRFLTPDGKSMTALHDFTMTVDRGEFACVVGPTGCGKSTTLNLVTGLAKPSAGEVRVMGGAVTGIHKDVGFVFQADALFPWRSVLDNVAAGPIYRGMPKAQAYEKARDWIARVGLARFEKHYPHQLSGGMRKRVALAQTFINEPKILLMDEPFSALDVQTRTLMQDELLSLWSGSGASVVFVTHDLEEAVALADKVYVLTAGPATVKSVYHIDLPRPRVMEEIRYDAAFVEKCRVIWNDLREEVQIGQQRTLKTGH</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_1949"/>
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        <property type="gene ID" value="AZC_1949"/>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="318" mass="35033" checksum="FF42F92179F46E56" modified="2007-12-04" version="1">MPPSRHWTHGLDWNLLRTFLVIAEERSVTRAAERLLLQQPSVSAALKRLEETCECRLFERGCRPMRLTPQGEALYQQCRELYRAILTLDPGIAPSSSSLTGLVRIEIVTHLVNSGLDAVVRRLNAKHPGISYNVEVSSSYGIVRAVSQQLTPFGICLLAKPLPTLSCRFLFRERFGVFCGRGHRLFGVEAIDFDAIRNEPWVSFACAEVSNSLEPMLTLRLGADIARRVVATSPDLFEVRRFVNAGVGIGTLPLEAAARDVAEGALWPLPLPGLDALGADVYFLSNPALRYSPAEQAFMEEMSAFEDANADIEAPVGP</sequence>
</entry>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1978"/>
    <dbReference type="EnsemblBacteria" id="BAF87976">
        <property type="protein sequence ID" value="BAF87976"/>
        <property type="gene ID" value="AZC_1978"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1978"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_2_2_5"/>
    <dbReference type="OMA" id="MKASRWR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="97"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="293" mass="31019" checksum="0FA06B30DA484EF6" modified="2007-12-04" version="1">MMSEAKSTIVPTSVGIETVQSNPVVHPGGRKKKASRGVNGTAIMLVGLVLLFTGWALAVKYMEIPSYILPSPAAVWNALWSGLAVSPASPLGYYLPLWGTLKNAAIGLAIGSGLGLLLGSLMAESRVIEKLLMPYAFALQSLPKVAIAPLVVIWFGFGDGSKIAISALLAFFPMLINSFTGLRSVEPERIDLMRSLSASRFETYRIVKLPNAAPYIFAGLDMAVVYALLGTIVAEFLGAQQGMGVVITQAQAVTDVAGVFAALVILGAMGILLHGIVRGLEARVVHWADRGRK</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-07-28" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8I491</accession>
    <name>LPXA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <shortName evidence="1">UDP-N-acetylglucosamine acyltransferase</shortName>
            <ecNumber evidence="1">2.3.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lpxA</name>
        <name type="ordered locus">AZC_1704</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3R)-hydroxyacyl-[ACP] + UDP-N-acetyl-alpha-D-glucosamine = a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:67812"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="2.3.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family. LpxA subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I491"/>
    <dbReference type="SMR" id="A8I491"/>
    <dbReference type="STRING" id="438753.AZC_1704"/>
    <dbReference type="EnsemblBacteria" id="BAF87702">
        <property type="protein sequence ID" value="BAF87702"/>
        <property type="gene ID" value="AZC_1704"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1704"/>
    <dbReference type="eggNOG" id="COG1043">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061249_0_0_5"/>
    <dbReference type="OMA" id="ECVTINR"/>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00387">
        <property type="entry name" value="LpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000134379" description="Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00387"/>
        </source>
    </evidence>
    <sequence length="271" mass="28621" checksum="401B0798E7C577A9" modified="2007-12-04" version="1">MNVALIDPTARVADGAWLADDVEVGPYCIVGPDVTLEDGVRLHAHVNVQGVTTLGARTQVYPFASLGTPPQSVHYKGEKTSLVVGTDCQIREHVTMNTGTASGRGVTRVGNNCMLMTAAHVAHDCLVGDNVIFANNATLGGHVEVGDNVFLGGLSAVHQFVRIGAQVMIGGVTGVREDVIPFGYAIGQNANLVGLNVVGMKRRGFSKSELHAARAAYRDLFFGEGTFAERLAGLRERQDASPFIKALVSFVDAGGKRALCHPSRGVVAQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I525</accession>
    <name>A8I525_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC opine/polyamine transporter periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1802</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170330.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1802"/>
    <dbReference type="EnsemblBacteria" id="BAF87800">
        <property type="protein sequence ID" value="BAF87800"/>
        <property type="gene ID" value="AZC_1802"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1802"/>
    <dbReference type="eggNOG" id="COG0687">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026974_1_5_5"/>
    <dbReference type="OMA" id="GHQQINV"/>
    <dbReference type="OrthoDB" id="447734at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006061">
        <property type="entry name" value="SBP_1_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01037">
        <property type="entry name" value="SBP_BACTERIAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723355" evidence="4">
        <location>
            <begin position="25"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="348" mass="37228" checksum="7620A42F09BD4E66" modified="2007-12-04" version="1">MTTSAKFGAAAALALGLFSQAAWAESNITVMAYSGLFQERYTKAVIEPFMKAHPDIKVTYFPLPSSAAMLGNLRAQKAAPQTDVAIMDVSVSKAGTDEGLFTKIDETNAPNVKDLYPNARIPDVAGVAVTFDNLVMLYNTDQVKEPPKSWMAMADKGYAGKVVIPGMPDIQGLSLVIILNKANGGTDYLKDVSKGIAAMVEIAPNVQTWEPKPEVYAPIVTGQAAVGAGWNARAQVNSQTSGGKLKATIPQEGTVFQINTINLVANGPGGDAAKTFVNYALSPEAQKAFTESMFYAPTNAKADISPEALDRTAVKFMDKVIPVDWIALAKVRDAIGEQWRRRVLPASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8I597</accession>
    <name>A8I597_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two component sensor kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170775.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2248"/>
    <dbReference type="EnsemblBacteria" id="BAF88246">
        <property type="protein sequence ID" value="BAF88246"/>
        <property type="gene ID" value="AZC_2248"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2248"/>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_23_1_5"/>
    <dbReference type="OMA" id="WKANALA"/>
    <dbReference type="OrthoDB" id="1827824at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="443"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="596"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="811" mass="85774" checksum="4545F698FF2AC01C" modified="2007-12-04" version="1">MSEQTQRMPPHQEALFAPLTREDLPSFVVLLPDLRVVAATPACAAFGVETGAEAPLSVKIVAKRVAMSLRRAPRLERVRLPGTQTPLPFACIGIHSPAGHVVLFADPLALAEGGRATRALPPRSGLPAVIPQYGRDADGRCLRFSWQMDAAGRLMRISPELPEALGGTEGDWVGRDFQELEDVGLIADAGPMRAALRTGGSFFGLTLRTGGHPARRIEFGGVPLFDQARQRRGTRGFGLLWGAEPQDEAPAGSDAEAQHFNVVPLHGGSLTPRERSAFHEIARTLSEAIEEWPKAATEARPELDETEPLREPDAGTASGAQAEGEDHLLDRLPIGIVVQQGGKTVRTNKTLLGWLGVRDTAEFVATGGLSPRLVRDSRHGGLDLETLHGDRLPVEVRLVASPWSGRPALVHVIRPIEGAPAAAAASPESPRGPASGVQMRVERSAARRQALDFIPYPVLLLDRDGTVEMANTAAADACGFTADDLEGEPFTILLAPGCHVQAVAMLDAAAAGKGAQSAPLTLRHRLGTEEQAEAMLVTTGDPAARFCLVLQTRTEAVVEAPSAVPVPAQPQPQPLAPLPPAGVPDDPRRVDAIVRRVSHDLRDPLTVLLGFVDSVRSNLYGPVGSRRYQQQAETAAAAGQALVDTLDDLGALALPPEPVTPVSLSPLVTDALAHLSDAARRRGVLLRTALSEDVTARANPEGFARLARELLTEAMEATPHGGQVIVTLTADDAAPNALLQVRDGGAALSEEEIAIALDPTRAATVSTRFSRAGRPFRLARLGALARAIGGDLALTRGLDTGLLVQVSLPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5D4</accession>
    <name>A8I5D4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
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        <property type="protein sequence ID" value="BAF88262"/>
        <property type="gene ID" value="AZC_2264"/>
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    <evidence type="ECO:0000259" key="1">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="Na/Pi_transpt"/>
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    </feature>
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        <location>
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            <end position="431"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
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    </evidence>
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            <dbReference type="Pfam" id="PF01895"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF88288.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="561" mass="59316" checksum="2BEA27AF0D2FA4E8" modified="2007-12-04" version="1">MVARGGAVLTFPVTLLDLAGCVALLLWGTHMVQSGVQSAFGPRLRTFLSGALKTRLHAFLAGLGVTAILQSSTATGLMVAGFAASGLVELAPALAVMLGANVGTTLVVQLLSFDISPLSPALILLGVMVYRRSNTQPPRDLGKVAIGLGLMLLALHQLIEFITPYEDAPNLRLLMGAVSTQPTVAVAVAAVLTWVAHSSVAVVLLAMSLAAKGVVSPEAAMALVIGANLGSALNPLLEASSASDPASRRVPFGNLLNRLVGVVVGLALLGPVSVALVELEPSVTRAVADYHTLFNLILAVVFLPLLKPFSALLCRLFPLKALPPDPARPLYLDAAALDTPVVALGNAAREALRLADILETMLSCTRDALDKDQGQRVAEAQKLDDVLDRLNAAIQAYLMRLDHETLGPEDRERFDEILAFATNLEHAGDVLDNSLLPLAAKRLKRGLAFSPEGKAEIATIIDRVIGNLHTAGALFMTNDARTARILAAEKAVFRDLETRATQNHFERMRGGVVESAETSSLQLDVVRDLKRINAHLVAGTAYPVLEREGELLPSRIAGELG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170842.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2315"/>
    <dbReference type="CAZy" id="GT83">
        <property type="family name" value="Glycosyltransferase Family 83"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG1807">
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="357"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="391"/>
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            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="56" xmlns="http://uniprot.org/uniprot">
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        <lineage>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Herder J.D."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    </reference>
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        <property type="protein sequence ID" value="BAF88147"/>
        <property type="gene ID" value="AZC_2149"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2149"/>
    <dbReference type="eggNOG" id="COG4397">
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        <property type="entry name" value="Phage_Mu_GpT"/>
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        <property type="entry name" value="Mu-like_gpT"/>
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        <location>
            <begin position="10"/>
            <end position="297"/>
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    </feature>
    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF10124"/>
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    </evidence>
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    <sequence length="300" mass="33533" checksum="A0D87AA0BC918943" modified="2007-12-04" version="1">MPRVLTPPLLEAINKGFKTNFQKGFSGVTALYWNLCTIVPSTSSEETYGWLGDIPKMREWIGDRHVHGLRAHGYAIRNRKFELTVSVQRDDIEDDRLGIYAPRFELLGQAAAEHPDDLVFGELIPQAWTRACYDGQPFFDTDHPVGLPGAQATVSNMQAGTGEPWMLLDLSRPLKPFIFQKRRDYNFVAKEDAKTSDRVFERDEYVYGSDARVGAGYGFWQMAFGSRAELTAANLRAAWNAITAFRSDNGTPLGVTPTHLVVGNTNFFTAKDILERDVIDGSTNTNRNLVTLLRAPKLAA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
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            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="protein sequence ID" value="BAF88198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2200"/>
    <dbReference type="EnsemblBacteria" id="BAF88198">
        <property type="protein sequence ID" value="BAF88198"/>
        <property type="gene ID" value="AZC_2200"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2200"/>
    <dbReference type="eggNOG" id="COG0658">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_011826_1_0_5"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025405">
        <property type="entry name" value="DUF4131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="DUF4131"/>
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    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="101"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
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    <feature type="transmembrane region" description="Helical" evidence="7">
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
                <person name="Lee KT."/>
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    </dbReference>
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        <property type="entry name" value="DHPICSNTHASE"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88683.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="315" mass="33199" checksum="3179C49B5EBFE26A" modified="2007-12-04" version="1">MTETFVQRLSGIHAATVVPMRADFSMDEDALAAHIGAVTRVKGIRGLLINGHAGENFVLSLAEKRRVVEIARTVAPKDCLLVSGVNHESSLEAAREAAEMAAAGADGLLVFPPNSWALGHADACTLMHHKMIADATALPLMLYGAPVGAGAMSYSSEVLSRLIDDPRFVAIKDGSWEVAAYEENLRLIQSRRPGFAVLGSGDEHLLTSYVIGSAGSQVSLAAVVPELVVALWDAAAAGDWARARQVHEQLYPLSVAIYRDAPGGRATARLKTCLKLLGRLGNDVVRPPQPSCDARENAALSAALRAAGVEVPVAA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF88770">
        <property type="protein sequence ID" value="BAF88770"/>
        <property type="gene ID" value="AZC_2772"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2772"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="AMP-bd_C"/>
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        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
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        <property type="entry name" value="AMP-dep_Synth/Lig"/>
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        <property type="entry name" value="ANL_N_sf"/>
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        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="45"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="434"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="530" mass="57918" checksum="DF6ED4C568E79AE4" modified="2007-12-04" version="1">MVGCDRRYQRKVMRGDDMRSSLPSPPPNRWRNLGDLIDRGGDLSRPALIDLSTAPPRVLTHAEADRLINGVARFLTDRGLKRGDRVAILSSNRAEVLLSYFGIMRAGFIAVPMNVKLPRDMIDYVVTDSGALFAFTDRANRPLVQGAVTFLDFDDDGPSGFHAAITPCDFATVPMAEGEIAQMLYTSGSTGRPKGVPLSHSGQLWSLDMRTSDGTRREDQRYLIAQPLFHMNGLFSAKTAFATNASIVLMPAFDVRPYVDAIATYDVTALSSVPTMFARIVKDADYVASRDMTSLKRIMMGSAPTTATLFSSVAALFPQATLVLTFGATETGPAIFGPHPDGRPTPPVSLGTPVPGTQVRLVDGPDADEGVLWVRNPAIMPGYHRKPELTAAVLKDGWYVTGDILRRDAEGFYYFVGRADDMFVCGGENIYPVEVERLLERHPGVQQAAVVPLPDAERGQMPVAFLVPKPGARLSAAEVKTFTLENGPAYQHPRRIALVSELPWAGTNKIDRAALKAEALRRESEQRWAS</sequence>
</entry>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="3">
        <location>
            <begin position="4"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="4">
        <location>
            <begin position="166"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="301" mass="30441" checksum="6D14D31D4D514553" modified="2007-12-04" version="1">MRTVAVIGLGAMGLGMAKSLLAAGLVVRGCDLSAAAVAALAEAGGTGCATPAEAVQGASVVVSVVVNADQTEAILFGPQGIAEVMPANAVFVSCATMAPEKARDFAGRLEALGRLYLDAPISGGAARAAKGELTILASGRPEAFAAADAALEAMSAKLYRLGDAAGTGAAFKMINQLLAGVHIAAACEAITFAARQDLDLEMVYEVITASAGNSWMFENRIPHVLAGDYRPLSAVEIFVKDLGIIQDMARAARYPVPLAAAALQLYLGAAGAGMGRDDDSSLARLYAGLSGVTLPKGESVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9K0</accession>
    <name>A8I9K0_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Putative oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171324.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2800"/>
    <dbReference type="EnsemblBacteria" id="BAF88798">
        <property type="protein sequence ID" value="BAF88798"/>
        <property type="gene ID" value="AZC_2800"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2800"/>
    <dbReference type="eggNOG" id="COG2080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052511_3_0_5"/>
    <dbReference type="OMA" id="RSCVIPL"/>
    <dbReference type="OrthoDB" id="1819473at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="164" mass="17090" checksum="C725B98C1ECE3071" modified="2007-12-04" version="1">MADEVAFTVNGVPHGFALPRETPLIYVLRNDLGLNGPKFGCGLGECGACTVLVDGVAARSCVTKLASVEGRAVTTLEGLGTLAAPHPVQAAFIAEQGAQCGYCLNGMIMTTVAFLKRNPSPTEAEAREALRYNLCRCGTHVEILRSVLRAASDMAAAPETSVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9W1</accession>
    <name>A8I9W1_AZOC5</name>
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        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipB</name>
        <name evidence="12" type="ordered locus">AZC_2839</name>
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    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2839"/>
    <dbReference type="EnsemblBacteria" id="BAF88837">
        <property type="protein sequence ID" value="BAF88837"/>
        <property type="gene ID" value="AZC_2839"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2839"/>
    <dbReference type="eggNOG" id="COG0321">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035168_3_0_5"/>
    <dbReference type="OMA" id="GEVTYHC"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="66"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="104"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="189"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="247" mass="26913" checksum="D2EBB475D200920A" modified="2007-12-04" version="1">MDGTSATLQNLSQMNVSSRPRSTLTTAFLPKDAAAPPVDWTISDTPVAYPDAVAAMEARAAAIAAGEAPELVWLVEHPPLYTAGTSARREDLIDQRFPVYESGRGGQFTYHGPGQRVTYVMLDLKRRDPDLRRYVGALEAWLIATLAAFNITGERREDRVGVWVPRGGGVEDKIAAIGIRVRQWVSFHGISLNVDPDLTHFGGIVPCGVREHGVTSFTDLGLLVSMPEVDSVLRVAFEEIFGPTRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA04</accession>
    <name>A8IA04_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170973.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2447"/>
    <dbReference type="EnsemblBacteria" id="BAF88445">
        <property type="protein sequence ID" value="BAF88445"/>
        <property type="gene ID" value="AZC_2447"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2447"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_1_3_5"/>
    <dbReference type="OMA" id="NIVPYAY"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724265" evidence="1">
        <location>
            <begin position="35"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="54"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="350" mass="37877" checksum="7D2760B6D390C603" modified="2007-12-04" version="1">MTERVEKTRRTGPSRRHVMAGLAAGLAMMGGAGAAPARAADLTKATLRLKWLPQTQFAGFYVAVAKGYYKDEGIDLTINPGGPNLLAENLVATGADTFGLSGGLDSVFAARDKGMPVVCIGISHQMTPFVFVARADGPVKTIQDFKGKTVTTWFTGANHVLNAILAKNGIDPALVTIQPQQVSVTPFIDGQVDVITATRYNEYYTIKTRMGEEKLRTFVAEDSGITFPRDTLIVSETTAKEKPELVKAFLRASIKGWKDAFNDPKGAVDTVMAIAPTLDRAHQEFQLAEAKKLMVAGKVPEKGLFWIDMDSVKITQDLFLNAKVISKPVDLGATFNTSFLEAIPLADRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAC1</accession>
    <name>A8IAC1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydantoin racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2490"/>
    <dbReference type="EnsemblBacteria" id="BAF88488">
        <property type="protein sequence ID" value="BAF88488"/>
        <property type="gene ID" value="AZC_2490"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2490"/>
    <dbReference type="eggNOG" id="COG4126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053002_0_0_5"/>
    <dbReference type="OMA" id="VIACYSD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036361">
        <property type="term" value="F:racemase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="221" mass="23496" checksum="F00CBED28AE78309" modified="2007-12-04" version="1">MMTRPDILVVNPNSNAVVTAGFDAALAPLRFSDGPAIRCVTLEDGPYGVETQADVESVSLPLRRLVEREQGAGAFVIACYSDPGLHVCREGTKAPVFGICEAGLLTALARGDRFGVIAIGEGTMARHQRYVRQMGLYERFAGERPLKMSVAESAAGENTLARMIEVGRDLMRLDRCDVIVMGCAGMSRHRRPLEEALGVPVVDPVLAAVTMAIGAVQAAGA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-01-11" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAC9</accession>
    <name>RUTB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ureidoacrylate amidohydrolase RutB</fullName>
            <ecNumber evidence="1">3.5.1.110</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rutB</name>
        <name type="ordered locus">AZC_2493</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(Z)-3-ureidoacrylate + H(+) + H2O = (Z)-3-aminoacrylate + CO2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:42624"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:59891"/>
            <dbReference type="ChEBI" id="CHEBI:59894"/>
            <dbReference type="EC" id="3.5.1.110"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(Z)-3-ureidoacrylate + H2O = (Z)-3-aminoacrylate + carbamate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31603"/>
            <dbReference type="ChEBI" id="CHEBI:13941"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59891"/>
            <dbReference type="ChEBI" id="CHEBI:59894"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(Z)-2-methylureidoacrylate + H(+) + H2O = (Z)-2-methylaminoacrylate + CO2 + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:42620"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:143783"/>
            <dbReference type="ChEBI" id="CHEBI:145735"/>
            <dbReference type="EC" id="3.5.1.110"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the isochorismatase family. RutB subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.110" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAC9"/>
    <dbReference type="SMR" id="A8IAC9"/>
    <dbReference type="STRING" id="438753.AZC_2493"/>
    <dbReference type="EnsemblBacteria" id="BAF88491">
        <property type="protein sequence ID" value="BAF88491"/>
        <property type="gene ID" value="AZC_2493"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2493"/>
    <dbReference type="eggNOG" id="COG1335">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068979_8_0_5"/>
    <dbReference type="OMA" id="WHKSNAL"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019740">
        <property type="term" value="P:nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006212">
        <property type="term" value="P:uracil catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00830">
        <property type="entry name" value="RutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019916">
        <property type="entry name" value="RutB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03614">
        <property type="entry name" value="RutB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000402648" description="Ureidoacrylate amidohydrolase RutB">
        <location>
            <begin position="1"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00830"/>
        </source>
    </evidence>
    <sequence length="227" mass="24689" checksum="AEC7651D22B3B7A1" modified="2007-12-04" version="1">MLPARPEPLSVAVEETAVVVVDMQNAYASPGGYLDIAGFDISGAKAAISAIAETVEAARAAGVTVIYFQNGWDKDYVEAGGPGSPNWHKSNALKTMRKKPELQGQLLAKGGWDYALVDQLAPQPGDIVVPKPRYSGFFNSQFDSILRARGIRNLVFCGIATNVCVESTLRDGFHLEYFGILLEDATHQAGPEYVQKAAIYNVETFFGWVSTVADFRRAFAQIPPKED</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAN8</accession>
    <name>RS11_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsK</name>
        <name type="ordered locus">AZC_2531</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171057.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAN8"/>
    <dbReference type="SMR" id="A8IAN8"/>
    <dbReference type="STRING" id="438753.AZC_2531"/>
    <dbReference type="EnsemblBacteria" id="BAF88529">
        <property type="protein sequence ID" value="BAF88529"/>
        <property type="gene ID" value="AZC_2531"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2531"/>
    <dbReference type="eggNOG" id="COG0100">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072439_5_0_5"/>
    <dbReference type="OMA" id="KWGVAHI"/>
    <dbReference type="OrthoDB" id="1713391at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
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        <property type="entry name" value="RIBOSOMAL_S11"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
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    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000073200" description="30S ribosomal protein S11">
        <location>
            <begin position="1"/>
            <end position="129"/>
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    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
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    </evidence>
    <sequence length="129" mass="13817" checksum="6DE8AEA2BB235D02" modified="2007-12-04" version="1">MAKEAARVKRRERKNIASGVAHVNASFNNTMITITDAQGNTISWSSAGAMGFKGSRKSTPYAAQLAAEDAARKAAEHGMRTLEVEVSGPGSGRESALRALQAAGFLVTSIRDVTPIPHNGCRPRKRRRV</sequence>
</entry>
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            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
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        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ordered locus">AZC_2546</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF88544">
        <property type="protein sequence ID" value="BAF88544"/>
        <property type="gene ID" value="AZC_2546"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2546"/>
    <dbReference type="eggNOG" id="COG0255">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:structural constituent of ribosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="73" mass="8468" checksum="86A04266F451A45F" modified="2007-12-04" version="1">MRERLMKAEDVRALSPDQLADELLKLKKEQFNLRFQKATGQMENTARSKEIRRDIARIKTVQNAKRVAAANVK</sequence>
</entry>
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    <accession>A8IAV3</accession>
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        <alternativeName>
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            <fullName evidence="2">Iron-independent fumarase</fullName>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
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        <property type="protein sequence ID" value="BAF88564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF88564">
        <property type="protein sequence ID" value="BAF88564"/>
        <property type="gene ID" value="AZC_2566"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2566"/>
    <dbReference type="eggNOG" id="COG0114">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021594_4_1_5"/>
    <dbReference type="OMA" id="HDSMGEV"/>
    <dbReference type="OrthoDB" id="734949at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="12"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="408"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding (B site)" evidence="2">
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            <begin position="129"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
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            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="324"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="463" mass="49199" checksum="78A00D09B17977C6" modified="2007-12-04" version="1">MSATRVETDTFGPIEVPADRYWGAQAQRSYGNFKIGWERQPLPVVRALGIVKRAAAEANRDLGKLDGKIADAIVAAAQEVIDGKLDDHFPLVVWQTGSGTQSNMNANEVISNRAIEMLGGEKGSKKPVHPNDHVNMSQSSNDTYPTAMHVACSEEIVHRLLPALKTLHGALDAKAKQWASIIKIGRTHTQDATPLTLGQEFSGYAKQVENGIARIESTLPALMQLAQGGTAVGTGLNAPVGFAEKVAEKIAAITGLPFTTAPNKFEALAAHDAMVFSHGAINTVAASLFKIANDIRFLGSGPRSGLGELALPENEPGSSIMPGKVNPTQCEALTQVCVQVFGNNAALTFAGSQGHFELNVFNPVMAYNFLQSVRLIADAAVSFTEHCVVGIEPREDNIKAGLERSLMLVTALAPKIGYDAAAKIAKTAHKNGTTLREEAVGGGYVTNEEFDAVVRPENMISPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB62</accession>
    <name>A8IB62_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171139.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2615"/>
    <dbReference type="EnsemblBacteria" id="BAF88613">
        <property type="protein sequence ID" value="BAF88613"/>
        <property type="gene ID" value="AZC_2615"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2615"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_4_5"/>
    <dbReference type="OMA" id="NTSIYLM"/>
    <dbReference type="OrthoDB" id="685252at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720929" evidence="2">
        <location>
            <begin position="25"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="40"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="264" mass="28146" checksum="8841EB9A1D5CB350" modified="2007-12-04" version="1">MSLKSLTRGLLVAAGIGLAGLASAASASATTLNEIVQRGTVRIGVLIGGPPMGMVDDKGNPTGYDYDVAVLIAKYLGVKAEYVALTPPARIPALQTGRVDFLIATLNPTPERARSVMFTMPYNAFNMVVVTKGAKVESLDALKGKKVGATRGTPQEAALRRAGGINVTIFEDDSITTQALLSGQVEAAALPETLVLSVAKQNPDAKLEIGFSIYAQGNSMAVRPGDFEILQWLNNTIYFMKKNGELDTLYRKWTDTPLPPLETF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB72</accession>
    <name>A8IB72_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Akiba N."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
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                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
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                <person name="Wiley G.B."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </evidence>
    <sequence length="3949" mass="374591" checksum="0F7FA4E39F7FF7AC" modified="2007-12-04" version="1">MRRYGVGGEHSGQSGAAHPPCGRVESALRFVPERPARWPASSGFSVRMSVPSAPIAPALRAALPPDRRRSRMAQVLLSSCATVALMLAPVVVSLGVALPRPAQAQTHTLNPTNTGVVLGNYSGSTDFLITAATTVSASTASAVYGGNTNVWTLTNQGTVSAPSYTGVTFTAGGLVTNSGTGSLISGGSGVRITGGAGTVINEGAITASNLGVYLNSGGSVTNSGTASSITADVFGVYIRDVAGTLTNAGTIRSTSSSAVAISYTAASVNNAATGVITGANRGVYFFALGANATLTNAGQITGQTSFGVTFDQGSVSNTAGGTITGAGGLQITGIATVVNDGLITATGTFSGTTSTDSNSAGVRNSASSTLITNSAGGTISGAAMGIYLASGGRVTNAGTIITTGGFAIYSKAGSPTITNSGLIQGGTTTPAVYLGFGGTVTNSAGGTISGGSRGIAVKGAAGVVTNSGTVTATAGSGVGVGLTNGGRVTNANGGIISGSVGVTGAGAATTVINYGTIIGNSGTAISMTGSFNDTVQLRPGAVVTGIMNAGAGTDTLQFAGTSAGTISGVRALSFENVSVLANADWTLTGTNSFGAATFANNGKLTVAAAATASSSGPIQNATTASVLTVAGSLNSSGGLTNAAGASLVVLSTGTFSNSGTLNNSGTSASISIAGSMVNGGVVNNSGVGAGITIAAGGVLNNSATLSNSRTLTNRGTLLNTYGTFINTGLLTNSGSIAGTVTLTSTGTLDNQLGGIISATSVAAVTNASGVTPTLTNAGTIAGTNGPGVSLTAGGKVTNSGTASFISGSFGINITGAAGTVINDGTISAPSSYPRTGINLSGGGSINNTGTASVIAGGNYGVVVSGGTATLVNSGTVTGGAGNAVFFTAGGAVATITNYGTIASTSRQALYLQSGGVVTNAAGATISGTAAGAYLLNAYGAGSTVTNAGTIIGTNTTSGVGVLVNVTGFANTVVNSGTIIGNGGTAVRFVGTSNDVVRLLPGGVFTGVVDAGAGTDTLEFGGTTSATFTGLGGSGFINFEQFNVLSGANWTFTGTNTVASALAMTNSGTMTVASGGTFTNAGTLSNAGALTLDGTLLNSGSMTNSGSIAGAVTLTGTGVLTNAATGTITGATTSVGVFAYAGASGGVQNAGTITGLEAVWMNGSGFVNNAGTGSQIIGTYIGVVGFGVPINVTNEGTIRATTLTNGHAYGLYLQNGGTITNSGSASLISSADRAIQFISDAGVVTNAGTITGATYGVLFASGTFNNALTNSGTISGGTKAVAFGAGNDLLTLQAGATFIGVVDGGAGTNTLAFDGTGGSFTGLGGASFVNFGLVQVNSGASWTFTGANTISSGVTLTNSGTLANSGTLINAGVLTATTGVLTSSGLLSNSGTITGTETLTSGGVLDNQLGALVTTTGTGVVGISGTPTVTNAGTISAGGTSIFLNTGGVVANNGTASLISGGSGINVTSGNLSLTNAGTIIASSGQGVVVQAGAGSVTNAATGTISGAMSGVSFANTSSVVASIVNDGLISSSGGFGANMDWGVVTNHAGGTISGAMGAQLGTGTLINSGTITGATGPGVVSNGGGNIIGNDANGRITGATYGVKMFGGTLTNSGTILATGTSGVGVYSFNTDTVTNVGTAARIAGTLTGVQLRNAGSLLRNEGTILGSAGYGADQTTNGIIVNFGATALISGGLGGILISNGTTGNVMSVSIANAGTIAGTGTAGFGIKTMDGLGTIANTGSITGGTAGTGVFLDAGGTVHNAATGLISGGNDGIYARGAAGTITNAGTIAGTGTAGVGIAFSGTLANTLINSGAIIGNGGTAVQFGAGDDLLQVLSGAAFTGIVDGGAGSNTLEFVSGTGTLSGITNFATVLVDAGASWTLTSAASATTLSNAGSLSNTGTLTITGLFSNSGTLVNSGTVLAGSGTLSNAGLLTNSGSIVGTVSVTATGIVTNQAGGRITGVLAGVTGAGATLANAGTISATSTAGTAVVLSGAAQVSNSGSAAVMSGGLTGVSLGGLGTLTNSGSITGGTGMGASLAAGGSIANSDTAAVISGGLTGIVLGGLGTVSNAGTIIGALGYGVGLALGGSISNSGLISGGIAGVQVASGMGTLTNTGTLGSATSIGVSFAAGGTISNSGSAAVISGGMTGVVLGGLAALVNAGTIAGTLGYGVALALGGTITNSGTISGGTAGVQISGGTVLITNTGTIAGTGTAGIGVLFSAGASGTIDNYGVISGAGGTAVKFAGGTNRLILEGGSTLIGTADGSLGSNTLVVRDNATLSGVNAIGFQYVGFINATNAIGVGSTVTNATVISGTLTNQGTLNGRVTVDAGAVLNTSGVVLVSASSTNSGVIANSGTFTLSSTLVNNGTLANTGTFITTAGLFQNSGLLTNSGSIFGTLGVGGTGVVRNEVGGSIVGDLHAMFISGGTMANAGTLIATGTAGRGVEISTGTISNIGTASLIRGGQTGVASTSNGTVRNEGTIIGSSEFGVWVVNIGAVTNTGSASLIQGAISGIKMVGGGPVMNQGTIIGLANSGIDLSVGSTITNAGVGSRIQGAVNGVIVGNGAVLNEGTILGTSGIGVSLSGTSLANAGTASFIQGGQTGVDFGSAGTITNEGTIIGVSGSGIALRMGGNVTNSGLVSGATAGVSVAFGTTMLTNTGTIAGTGTAGVGVLFMGYASGTIDNFGVISGAGGTAVKFAGGTNRLILEGGSTLIGAADGSLGVNTLVVRDSATLSGVSAIGFQYVGFMDATNAIDAGSTITNPVVIAGTLTNQGTLNGKVSVDAGAVLNTSGLVAAGASSANAGTIANSGSFSVLASLLNTGTLINTAALDVAGTLATSGSLSNAGRLALAGTLANSGVFSNSGTLLNSGVLSNATTMSNSGVISGAGLFTNAGSFANSGSVLGAIALVGTGSVNNQAGGRISGTQAAVVGGSGGNVVANAGTITTSGAGSTAVALASGTIANSGSTALIQGAATGVSASGIATVANSGTIAGISGTGVDLAAGGLVTNSGLITGATTGVTISSGTATITNTGTISGTGNAGIGVLFTGGASGTIDNFGTISGAGGTAVQFAGGTNRLILESGSALIGLADGSLGVNTLVVEGSAVLDTVQVLGFRYVAFLNATQAVDAGSTISNAVVLSGTLTNRGTLGGNLQVSAGATLDNSGVVAATGTTTINGQVVSGGTFANSGTLTSTGTIASSGTLSNSGSLVNDGTLANSGSMANSGTISGSGTFANTGSFANTGAVLGTVNGVTGTGTITNSGTIIGTADTGVNLGSGGVLTNTTGGFIQGGVFGVQVGTGGTVVNAGTILDDAIAGLALGSNASLTNSGTIGGVIGLQFTGTGASATNSGTITGTGGTAIQFDAGVNSLTLTTGSVLEGGIDGGGGAGRITLAGSGTLSSTIANFGSGSALTIAGGANWIASGSWTIGAVTNSGTLQPGAVGSSLKLTGNFVQTSGGTLQVAVNPQGQSSQLLVSGTATLSGTLAVLAGSGSYGASTTYSILTSTALSGQFDTVTTDLAFLTPSLTYGSNTVSLTLSTGSTPVRFSSVALTLNQYATANAVQAGGANSALYQAVVGQNAAGARTAFTMLSGEAYASVITALLDDSRVVPQTLMNRLRQQAYGEAGGAVVALGTGGPVTLSSSALASVGQGSTGTVQPSGVAIARPNGGMADGGASRLVAWGEAFGGWGQISGTSNAAAVSHDRSGFMTGLDALIGEDWRVGLAGGYTSTDLTISGRASSADIGTYSLGLYAGRAFGPVNVRLGAAYSWSDVDMARTVAFPGFQQGVSSSYGVDTAQVFGEVGYGFSWNGLALEPFAGLAYVHMNTGAGQEVGGAAALTLHSSTADLTYSTLGLRLGTSWTLGNGTTLMPRLMVGWQHAFGDLDPAAYLAFGTGVNFSVTGAPLARDAALLDLGADWKLDDSMKLGVSYRGTLSNAVQDHAVTGSFTWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID11</accession>
    <name>A8ID11_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC-type branched-chain amino acid transport ATPase component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_2869</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171393.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2869"/>
    <dbReference type="EnsemblBacteria" id="BAF88867">
        <property type="protein sequence ID" value="BAF88867"/>
        <property type="gene ID" value="AZC_2869"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2869"/>
    <dbReference type="eggNOG" id="COG0411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_5"/>
    <dbReference type="OMA" id="DMAFWIQ"/>
    <dbReference type="OrthoDB" id="1179151at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="236" mass="25154" checksum="FD8F0D15AB545AB2" modified="2007-12-04" version="1">MLALEGVSVRFGGLLALSNISFSVEKGEILGLVGPNGAGKTTLFNSISGLVRARGRISVGGQDITGLPLHRRAKAGIGRTFQIPQPMHHLTVRENLTVAQVFGAGRNDPARINEILEVMQLSHKADADAASALALQELKRLEIAKALATEPRLLLLDEVLAGLESNAKRSFMLKLKELHALFGLTIVIVEHDIETISNLCTRAVVLNFGQLIADGTPAEVFNNPAVVESYTGAAHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDR5</accession>
    <name>A8IDR5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2981"/>
    <dbReference type="EnsemblBacteria" id="BAF88979">
        <property type="protein sequence ID" value="BAF88979"/>
        <property type="gene ID" value="AZC_2981"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2981"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3850">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="VEEMADY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="216"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="309"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="461"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="565" mass="58879" checksum="EAF71EB5C54C26DF" modified="2007-12-04" version="1">MLYNNLKMIWKIVALLVLLGAVSIGGALYGASQSTAINDLLSGIIEGPAAAATRMARANRFMVRTELAIYQLINAPDDASVAAADKAMNEVVETARGIFSDAAKLAPAFSSRIESIGSSFSRTMETACASTIKLSLVARTPAENARAAALMRSECEPAIEKISQDSVALTAEMQTYMADENKRADDVTASANATSISVIVAATVLVIGLALFLVRRSIVRPLEAMMGVMEAMGHGDLSRKPDETGRADEIGAMSRTLTVLGEQLQAAEAARQQQAEREAAERLQIQKRQKLAEAFVAEIQQIAATFADSSAQVADSARNLSATAEQTSRQAQAVASAAEEAATNVQTVAASSEELAASVREITGQVSHSASVAEVAFREAETSNERIVELARSAQAIGDVIVLIKGIADQTNLLALNATIESARAGEAGKGFAVVASEVKELAAQTGKATDEIASKIAEIQQATQGTVSSMGEIIRVVGNIKQISSSIAGAVEQQGAATGEIAQNCQQAATGTQQVTENIGGVGQAAELTGSASSQLLTLSQGLSTQAVDLRRTVERFVSDLHAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDZ2</accession>
    <name>DCTA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C4-dicarboxylate transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dctA</name>
        <name type="ordered locus">AZC_3014</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171538.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IDZ2"/>
    <dbReference type="SMR" id="A8IDZ2"/>
    <dbReference type="STRING" id="438753.AZC_3014"/>
    <dbReference type="EnsemblBacteria" id="BAF89012">
        <property type="protein sequence ID" value="BAF89012"/>
        <property type="gene ID" value="AZC_3014"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3014"/>
    <dbReference type="eggNOG" id="COG1301">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019375_7_0_5"/>
    <dbReference type="OMA" id="YLYIAVI"/>
    <dbReference type="OrthoDB" id="781228at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006835">
        <property type="term" value="P:dicarboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01300">
        <property type="entry name" value="C4_dicarb_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023954">
        <property type="entry name" value="C4_dicarb_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42865">
        <property type="entry name" value="PTHR42865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00713">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00714">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0769">Symport</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000321968" description="C4-dicarboxylate transport protein">
        <location>
            <begin position="1"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01300"/>
        </source>
    </evidence>
    <sequence length="446" mass="46893" checksum="33AA5AB784A30FDD" modified="2007-12-04" version="1">MAPVIPAASAPHKPRKFYQHLYVQVLAAIAIGILLGHFYPDLGTQMKPLGDAFIKLVKMVIAPVIFLTVVTGIAGMRDLAKVGRVAGKAMIYFLTFSTLALIIGLIIANVVQPGAGMHIAPASLDPKAVASYAAKAHDASIIGFLMNIIPDTPISALGSGDILQVLFFSVLFGIALAGVGDRGEPVMNVLVSASQAMFRLVHILMKAAPIGAFGAMAFTIGRYGIGSVANLAFLILTFYITSFLFVVVVLGLVARYNGFSIFALLRYIKEELLLVLGTSSSEAALPSLIEKMERAGCRKSVVGLVIPTGYSFNLDGTNIYMTLAALFIAQATDIHLSLGDQILLLLVAMLSSKGAAGITGAGFITLAATLSVVPTVPLAGMALILGIDRFMSECRAITNFIGNAVATIVVARWEGELDKDKLAAALSGRISVEDDDLPIEATSPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEW2</accession>
    <name>A8IEW2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative salicylate hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3543</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="protein sequence ID" value="BAF89541"/>
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            <dbReference type="SAM" id="Phobius"/>
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        <source>
            <dbReference type="Pfam" id="PF01494"/>
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    </evidence>
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    </evidence>
    <sequence length="386" mass="40926" checksum="39509B2D59C7A024" modified="2007-12-04" version="1">MGQTSPASALIVGAGIGGLACGIALRRAGLAVRMVEQADELAEVGAGLQLTPNATRHLRDFGVLDALETVAVKPRALEVRDGQTFGLLARCDYAPAVAKYGAPFLVLHRADLQKALADGAKAAGCDILLGARLQSLDTHGDNLRAVAEQEAGLIAETADIVIGADGVRSLVREHLQVGVRPSFARRVAYRATIPVRADTPPDVRLFLGPDAHLVTYPIRAGAAVNVVAIVRQDRPVNRWSEPGDASTVHEAFSQWAPEVRSLLLDASSFLCWGLYDVDPLPRWGAGRTTLLGDAAHAMLPFLAQGAAQAIEDAATLGSVLGAGGPLEPALRRYEALRQARAARVQRGARRNAVIYHLKGPARFARDLALRATGGSLLSRYDWLYGG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="438753.AZC_0146"/>
    <dbReference type="EnsemblBacteria" id="BAF86144">
        <property type="protein sequence ID" value="BAF86144"/>
        <property type="gene ID" value="AZC_0146"/>
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    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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            <end position="41"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="386" mass="40177" checksum="05AC330889B9E740" modified="2007-12-04" version="1">MLETLKRLIPPIGPVSPSEQVRAACGALLGIFLTGFITRLALGSGSAVPLLIAPMGASAVLLFAVPSSPLAQPWSILGGNLVASTVGVTATMWIPDPFLAGGVGVGGAIALMLALRCVHPPSGAVALTAVVGGPAVTKLGYAFVLWPVMVNSLVILSVAIAYNNLTRRRYPHLAPLKTPAPAAQEARAATFAHQDIIAALREADELIDVDPSDLEDILHRAQLRAFDRRSDGLTCGDIMTRHVLAVSPATPILEAMELLRSGRTKVLPVTSDKAEVIGVLTQTDLLDKVDWDHKGPRLGFGRRVSAALRAGRAPDGTVEEIMSTPVTAVTAEMRVAALVPLMSQSGMHHIPVVDAKGQLAGVVSQGDLIAALIQGRGEAPPAQVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHC2</accession>
    <name>A8IHC2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3256</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3256"/>
    <dbReference type="EnsemblBacteria" id="BAF89254">
        <property type="protein sequence ID" value="BAF89254"/>
        <property type="gene ID" value="AZC_3256"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3256"/>
    <dbReference type="eggNOG" id="ENOG502Z8VF">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042275_0_0_5"/>
    <dbReference type="OMA" id="VRFIECK"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="545" mass="59562" checksum="D94EE101E33EEBF3" modified="2007-12-04" version="1">MTCPMASVAQYLSEHGPSRSSRIVEAFVASGLSAEAARQRVSRAKPPVRSFPVPLLPKREAFLYLEKDRNGERFWQNFLRDLRETNSITAAAIDGVIARGGIIPVEQFAVVSGATVRPKTGQVPADTVARRLIKSDFLKEFHDPEYGRCFHTAPSLAMGTPAAMRARDITERVLLDGLREWCRKIGLASYNAIRIRGDEDLKPIGPFAFDLAGPSYLLPLQGSASKPGFVVADVFAEGILTVHEIQFFIRKARVLKASFKDIGILSIIVAEGFTGEAMTAGHAAGVMLATPKDLFGRRVGEAIASLCEVLKNAAKYASSSPERLTMLLNNLFDIEGRNKNLRGILFEMVAGYLARRTAMTMDMGVTAKDPSTGKTADIDVQTITNQNAIVTAIECKGKEPGGALSLAEVEEWLAKIPTFRAHYAQHGYLREAEQRFEIWTSGSIAPDALAKLKEEQVRRVKAKIDWKDGDAVLALARAGKEKALADALNQHFFRHPLAEVAKQFEADEAAGKVQSWMAPTKSKPPEFKGPAIEVVSLDDELDAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHE3</accession>
    <name>A8IHE3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative DNA segregation ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3264</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexamer. Forms a ring that surrounds DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3264"/>
    <dbReference type="EnsemblBacteria" id="BAF89262">
        <property type="protein sequence ID" value="BAF89262"/>
        <property type="gene ID" value="AZC_3264"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3264"/>
    <dbReference type="eggNOG" id="COG1674">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001981_1_1_5"/>
    <dbReference type="OMA" id="IIALKWA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
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        <location>
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    <feature type="compositionally biased region" description="Pro residues" evidence="6">
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        <ligand>
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    </feature>
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            <dbReference type="ARBA" id="ARBA00006474"/>
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            <dbReference type="ARBA" id="ARBA00023125"/>
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        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <dbReference type="InterPro" id="IPR041183">
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        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
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        <property type="entry name" value="Cyclophil_like2"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclophil_like2" evidence="1">
        <location>
            <begin position="40"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="148" mass="15932" checksum="1C9DA771B2B9ED44" modified="2007-12-04" version="1">MAQDMTRRSAVGAILAAGLPGGAYGGTGAGGSGMKIQFAFDSHVFTATLLDEAPAQELAAMLPLDLTIEDYSNNEKIAYLPRKLTRRANASFGNEAPGDLCYYAPWGNLVLYYAAYHYSPGLIRLGRLDDGVQPLMTRGKFPLRATRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHK6</accession>
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    <gene>
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    <organism evidence="3 4">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171812.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3289"/>
    <dbReference type="EnsemblBacteria" id="BAF89287">
        <property type="protein sequence ID" value="BAF89287"/>
        <property type="gene ID" value="AZC_3289"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3289"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_069356_27_0_5"/>
    <dbReference type="OMA" id="AAEHFFC"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="16"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="213" mass="23341" checksum="A0C30B0E2839C9BF" modified="2007-12-04" version="1">MGTGSATVAEDKGVLRPKALKALGAARAVFLDCGYDAASMDAIARAAGISKATLYAHFASKEDLFEALIRHECRDLKAKLTPLDASRPAGEELLRMARELRRLFAQDEGLTIYRIIVPVAHRFPRLARIFYEEGPETAIGQMADFFRAVSSTGRLAIPDPDVAAHQFLALVSDDLKLSCSLALPYRWAWDDEAVMRSSVSMFLSFYAVDGTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJP6</accession>
    <name>A8IJP6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bifunctional uridylyltransferase/uridylyl-removing enzyme</fullName>
            <shortName evidence="7">UTase/UR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Bifunctional [protein-PII] modification enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Bifunctional nitrogen sensor protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="7">[Protein-PII] uridylyltransferase</fullName>
                <shortName evidence="7">PII uridylyltransferase</shortName>
                <shortName evidence="7">UTase</shortName>
                <ecNumber evidence="7">2.7.7.59</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">[Protein-PII]-UMP uridylyl-removing enzyme</fullName>
                <shortName evidence="7">UR</shortName>
                <ecNumber evidence="7">3.1.4.-</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="7" type="primary">glnD</name>
        <name evidence="11" type="ordered locus">AZC_0338</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein-PII]-L-tyrosine + UTP = [protein-PII]-uridylyl-L-tyrosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13673"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
            <dbReference type="EC" id="2.7.7.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[protein-PII]-uridylyl-L-tyrosine + H2O = [protein-PII]-L-tyrosine + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:48600"/>
            <dbReference type="Rhea" id="RHEA-COMP:12147"/>
            <dbReference type="Rhea" id="RHEA-COMP:12148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:90602"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GlnD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.59" evidence="7"/>
    <dbReference type="EC" id="3.1.4.-" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0338"/>
    <dbReference type="EnsemblBacteria" id="BAF86336">
        <property type="protein sequence ID" value="BAF86336"/>
        <property type="gene ID" value="AZC_0338"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0338"/>
    <dbReference type="eggNOG" id="COG2844">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012833_1_0_5"/>
    <dbReference type="OMA" id="WIAKYVY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008773">
        <property type="term" value="F:[protein-PII] uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00277">
        <property type="entry name" value="PII_uridylyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013546">
        <property type="entry name" value="PII_UdlTrfase/GS_AdlTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010043">
        <property type="entry name" value="UTase/UR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47320">
        <property type="entry name" value="PTHR47320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08335">
        <property type="entry name" value="GlnD_UR_UTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006288">
        <property type="entry name" value="PII_uridyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01693">
        <property type="entry name" value="UTase_glnD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="2 7 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HD" evidence="10">
        <location>
            <begin position="551"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="790"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="899"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uridylyltransferase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="984" mass="109931" checksum="9138AEBCC5F4C24B" modified="2007-12-04" version="1">MRPFKVRLPDHPRCRCNSRAGVACKPRAVTAPQDWAKPEREAPSGSLKTSMTAPRPSRPSRTIGEPFEGTRLKAEVLALAKAHAGPKADLRPALVARLKQAMAEGRAEAERLLNADGSGRMCAIRLSALQDAVIAAAHEVATTVMYPIDNPSRAERMAVVAVGGYGRGMMAPGSDTDILFVLPYKQTAWGESVAEAMLYILWDLGLKVGHATRSVDECLRQARADVTIRTAILESRFLVGDKALFEDLEARFDKEVVEGTAAEFVAAKMAEREERLRRAGTSRYLVEPNVKESKGGLRDLHTLFWMAKYVYRVHSTDELVAKGVFTKEEARLFTRCEDFLWSVRCHLHFLTNRAEERLSFDVQREMAERLGYTSHPGQQDVERFMKHYFLVAKEVGDLTAILSAALEARHDKSVPGLKGMVARLRGAPKRVKLKESADFWIDNERLNVIDDEVFRRDPVNLIRLFAIADKRDVNFHPDALRLAARSLNLIDGKLRENPEANRLFLDVLCSKNAPEEVLRRMNETGVLGRFVPEFGKVVAMMQFNMYHHYTVDEHLLRCIGILSEIERKTNPENGLANDLMATIKPRHLLYVALLLHDIAKGRPEDHSIAGARICRKLCPRFGLSAAETETVAWLVEQHLVMSTVAQSRDLSDRKTIENFAAVVQNLDRMKMLTVLTTADIRAVGPGVWNGWKAQLLRTLYYETEPVLTGGFSEVDRGKRVQVAQAQLRHALADWTDEQFSTYAARHYPPYWLRVDLETKVRHARFILATEEAGKALATCAEIVAERGITVLTVLAPDHPKLLSVIAGACAAAGANIVDAQISTTTDGLALDTIAVRRAFDRDEDEERRAGRIRDAIEKALTGEVRLPEVMAKKLPKARRTFSVEPEVTVNNTWSNRHTVVEVSGIDRPGLLFELTNTLSRLNLNIASAHVATFGERAVDVFYVTDLMGAKITGAARQSTIRRALIGVFEGSFDEEEPPRRVVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJQ5</accession>
    <name>A8IJQ5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_0342</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0342"/>
    <dbReference type="EnsemblBacteria" id="BAF86340">
        <property type="protein sequence ID" value="BAF86340"/>
        <property type="gene ID" value="AZC_0342"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0342"/>
    <dbReference type="eggNOG" id="COG2314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081297_9_2_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007829">
        <property type="entry name" value="TM2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05154">
        <property type="entry name" value="TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="TM2" evidence="6">
        <location>
            <begin position="59"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="143" mass="15978" checksum="598666AC0D0B408D" modified="2007-12-04" version="1">MRRFGPAAPPCQIPLRTREGDQVRDGSPRRSLPMTDATPNLSIDEQILIETRLANEGPSLVVAYLLWIFLGIVSAHRFYLGRAGTAVIQILTFFIGIGFIWLLVDGFLIPGLARQKRERMRQQMIVERVAQLATAPRAVLPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJS1</accession>
    <name>A8IJS1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0349</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamate synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0349"/>
    <dbReference type="EnsemblBacteria" id="BAF86347">
        <property type="protein sequence ID" value="BAF86347"/>
        <property type="gene ID" value="AZC_0349"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0349"/>
    <dbReference type="eggNOG" id="COG0069">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026563_1_0_5"/>
    <dbReference type="OMA" id="CIGHPWE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldolase_TIM"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="UCP500060"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
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    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_synthase" evidence="4">
        <location>
            <begin position="194"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="578" mass="62928" checksum="27F11C49B04303E9" modified="2007-12-04" version="1">MRRQTAPDGPSRRGPAGVLPLWRARRKTMSGGLQPGTVLWLRRYSFFFAVVALATLALILSFASHAAWTWVFAAMMPFVAIGLFDAFQTRHSLLRNYPLIGSMRWLFEALRPYLRQYIVEGDEEGRPYPRMDRSLVYARAKQEEDRQPFGTELNAYSSEYEWMTHSLAPMPVAEEPFRVTVGGPQCAKPYSASVLNISAMSFGSLGRNAIEALNLGAKTGGFYHDTGEGGLSPYHRTYGGDIVWELGSGYFGCRNRDGSFSPERFAEKAADDQVKMVEIKLSQGAKPGHGGVLPAAKVTPEIAEIRGIALGEDCISPSRHPAFNSPVQLMEFVAKLRELSGGKPVGFKLCVGHPSETFAIVKAMLKTGIRPDFIVVDGSEGGTGAAPRELADHVGMPLREGLVLMRNALVGAGLRGEVKLAASGKVTSGFSMAANMAIGADWCNAARAFMFSLGCVQSLRCHTGLCPTGVATNDPHLQRGLVVEDKAERVANFQRHTVHALAELVAAAGLSHPSELLPHHLWHRVSPIEVRPLDKLYPFLAPFALVEAPEETPYGAEWRAADAESFTPRMDVGPLRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJY6</accession>
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        <submittedName>
            <fullName evidence="2">Putative glycosyltransferase</fullName>
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    </protein>
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        <name evidence="2" type="ordered locus">AZC_0377</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168908.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0377"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86375">
        <property type="protein sequence ID" value="BAF86375"/>
        <property type="gene ID" value="AZC_0377"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0377"/>
    <dbReference type="eggNOG" id="COG1215">
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    <dbReference type="HOGENOM" id="CLU_020629_0_0_5"/>
    <dbReference type="OrthoDB" id="724641at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="504"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="542"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="578"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="645" mass="69673" checksum="0A5AB959DFF27B03" modified="2007-12-04" version="1">MVGEAASDRKRTFYAKADALSPPSRWPVELQALHGTLPDSLIDWAAARARDLRVGGDEVLICAGLLTGPQASARLAAHLGLALQPPDVPLPVPPDLAPTVLRLQTFQTPPEDDLPGYVIAARGLYARRLASALREDPTLKRRARVIATEHLHGTLARQCADGIGRAAAFDLRAHRPDVSAGTIRFTRRMLLPATMAGAAVATAGLSAPLETLLIVQSLLSSIFLASATLRIATCLARPEEPPPLGLPDAALPLYSIIVPLYREERVLPRLVRALQAIDYPPEKLDIKIVVEPDDAPVHAALARMALPPWFEIIVAPDVGPRTKPKALNCALPFTRGSFVVVFDAEDVPDPDQLKRALAAFRQGGRNLACVQARLSVENADETWISRLFAAEYAGQFDVLLPGLAQLRMPILLGGTSNHFRRSMLELIGAWDPYNVTEDADLGVRLARAGWTTAVIGSSTAEEAPITRAAWMRQRTRWLKGWAQTLLVHGRQPLRLVRELGWGNLVPLLLLTAGPFASALLHPLCVAWLIADVVRGVFLTTPGTTLGVVATALSLTNLAIGYGAAAWSCGLGLKRRGQFALAPILILLPFYWLLLSVAAWRAVVQLIVRPYWWDKTEHGLGRLRPQAPLPAGAPARAPAGILTDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL20</accession>
    <name>A8IL20_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3978</name>
    </gene>
    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172498.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3978"/>
    <dbReference type="EnsemblBacteria" id="BAF89976">
        <property type="protein sequence ID" value="BAF89976"/>
        <property type="gene ID" value="AZC_3978"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3978"/>
    <dbReference type="eggNOG" id="COG1309">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_085682_0_0_5"/>
    <dbReference type="OMA" id="ISRTVQW"/>
    <dbReference type="OrthoDB" id="1437290at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="220" mass="24503" checksum="AAAC3EEDE61CDF0A" modified="2007-12-04" version="1">MTFETSRDAALRAFLQLLETTPFERIDLLDVAEHSGVPLPELRAAFASRRDLLAAFFKATDRQVLAASDDDFTDETAQERLFEVLMRRLDALEPHKEAVRALMRSARRNPPLAFLLLELSVKSQTWMLAAARLPASGLAGAVRARGLALLFGRVLDVWLDEEDPGLSRTMATLDRELANGAKLLGILDDLAYLARPWRIERRRRDVPPVTEEPGTADAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILL6</accession>
    <name>A8ILL6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome B561</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_4051</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172571.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4051"/>
    <dbReference type="EnsemblBacteria" id="BAF90049">
        <property type="protein sequence ID" value="BAF90049"/>
        <property type="gene ID" value="AZC_4051"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4051"/>
    <dbReference type="eggNOG" id="COG3038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_095321_4_2_5"/>
    <dbReference type="OMA" id="LKLYSWH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="7"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="179" mass="20036" checksum="2A006B485A4199E3" modified="2007-12-04" version="1">MRSERRRWSLPLRLLHWAMAALILGLLVLGWVMTHVRTDLGTTFAWYLWHKSFGFAVLVLVAARIATRLLSPAPREAMPPGWQRRAAHLAHGLLYLLMVAVPVAGWMMASASPLHLPTRPFNLFTLPDLVAPNAALFRQLELVHATLAYALLGLVVLHVAAALKHRFIDRDGVLARMGF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILM7</accession>
    <name>RL34_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpmH</name>
        <name type="ordered locus">AZC_4055</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172575.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ILM7"/>
    <dbReference type="SMR" id="A8ILM7"/>
    <dbReference type="STRING" id="438753.AZC_4055"/>
    <dbReference type="EnsemblBacteria" id="BAF90053">
        <property type="protein sequence ID" value="BAF90053"/>
        <property type="gene ID" value="AZC_4055"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4055"/>
    <dbReference type="eggNOG" id="COG0230">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_129938_2_0_5"/>
    <dbReference type="OrthoDB" id="2069770at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000072214" description="50S ribosomal protein L34">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <sequence length="44" mass="5217" checksum="E355859A1BF9ABC2" modified="2007-12-04" version="1">MKRTYQPSKLVRKRRHGFRARMATKNGRKIIAARRAHGRKRLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILP6</accession>
    <name>A8ILP6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4062</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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        </source>
    </evidence>
    <sequence length="342" mass="37209" checksum="1B405649A490E801" modified="2007-12-04" version="1">MSLLELGLDTFGDVTVAADGTPKPHAQVLRDVVAEAVLADEVSVDFIGLGEHHRDDFAISAPDVVLAAIAARTQRIRLGSAVTVLSSDDPIRVFQRFSTLDALSNGRAEVILGRGSFTESFPLFGFALQDYETLFTQKLDLFAALLTNAPVTWSGSIRPPLKDQKVFPPIETGRLKTWIGVGGTPESVVRAAHYGLPLMLAIIGGAPSRFRAYAELYRRALEEARQPALPLGVHSPGYIADTDEAAKEEMFGPYKTMRDRIGAERGWPPMGRDEFEREVSHGSLYVGSPETVARKIATTAKALGLDRFDLKYSGGPIPHAGQMRCVELYGTKVIPMVRDMLA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-04-29" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILV4</accession>
    <name>CH601_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chaperonin GroEL 1</fullName>
            <ecNumber evidence="1">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">60 kDa chaperonin 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Chaperonin-60 1</fullName>
            <shortName evidence="1">Cpn60 1</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">groEL1</name>
        <name evidence="1" type="synonym">groL1</name>
        <name type="ordered locus">AZC_0424</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + a folded polypeptide = ADP + phosphate + an unfolded polypeptide.</text>
            <dbReference type="EC" id="5.6.1.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168955.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ILV4"/>
    <dbReference type="SMR" id="A8ILV4"/>
    <dbReference type="STRING" id="438753.AZC_0424"/>
    <dbReference type="PRIDE" id="A8ILV4"/>
    <dbReference type="EnsemblBacteria" id="BAF86422">
        <property type="protein sequence ID" value="BAF86422"/>
        <property type="gene ID" value="AZC_0424"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0424"/>
    <dbReference type="eggNOG" id="COG0459">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016503_3_0_5"/>
    <dbReference type="OMA" id="TDTDKME"/>
    <dbReference type="OrthoDB" id="265347at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000331972" description="Chaperonin GroEL 1">
        <location>
            <begin position="1"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="87"/>
            <end position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <sequence length="547" mass="57254" checksum="496229DD4A0D993A" modified="2007-12-04" version="1">MAAKEVKFAGEAREKMLRGVDILANAVKVTLGPKGRNVVIEKSFGAPRITKDGVSVAKEIELEDKFENLGAQLVREVASKTNDLAGDGTTTATVLAQAIVKEGAKAVAAGMNPMDLKRGIDLATAAAVKDIQARAKKVSSSAEVAQVGTISANGDSSIGEMIAGAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFITNAEKMIADLEDPFLLIFEKKLSGLQPILPVLEAVVQSGKPLVIVAEDVEGEALATLVVNKLRGGLKVAAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGIKLENVTLAQLGRAKKVILEKEKTTIVDGVGEKAEIEARVAQIKAQIEETSSDYDREKLQERLAKLAGGVAVIRVGGSTEVEVKEKKDRVDDALNATRAAVEEGIVPGGGVALLRAKKAVEALSSENPDIAAGIKIVLRALEAPIRQIAENSGVEGSIVVGKVLESEGNFGFNAQTEQYVDLVAEGVVDPAKVVRTALQDASSVASLLVTTEALIAELPKKDAGMPAMPGGGMGGMGGMDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMM3</accession>
    <name>A8IMM3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AMP-binding enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0579</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169110.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0579"/>
    <dbReference type="EnsemblBacteria" id="BAF86577">
        <property type="protein sequence ID" value="BAF86577"/>
        <property type="gene ID" value="AZC_0579"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0579"/>
    <dbReference type="eggNOG" id="COG0318">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_7_5"/>
    <dbReference type="OMA" id="HITGRKT"/>
    <dbReference type="OrthoDB" id="377638at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="10"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="419"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="509" mass="54806" checksum="541916242AE0431E" modified="2007-12-04" version="1">MHIGFLFRRARAWHGASVALVDRVGPWTFEALMARIARFGQALAGLGLLRGERVALLLPDIREHLEADYGAMAAGFISVPLSAGMRRQDLVAHLRRTGARAVVAEATLIPMLAELRSELPDLRHIIALGGTVSGAHDYEDLLARASDRFLPPGESEDIAQLALSAGRTGQPKIVKLSHGNISAVAGNLIAGLRIGSDSVFLNVRPLWAPLQFMVLAYLLGGSRIVLGGAFDAERFPFQMARFSVTRSAMSPAQLAELLPHLAPEDVALNAMEMLHIGGAALPEAVCDEALNLVGPRISVHYGLAEAPFTCLLSAERLSVKRALRNELRTTVGRPFFGYETRLEGVEDTFATEQEGEILIRGPHVMTGYWDDPEATARVLCDGWLRTGDIGMLSSGYDLKVVGRTQDLIFSAGQTVSLREVEAAIARHPAIREVAVVGLPDGEAGEALTAFVVLKDESAASAEEILAFTHGALIGAKRPKAIHLRRELPRSDYGGIFLPGLLTDIVPLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMT1</accession>
    <name>A8IMT1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rubredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hupJ</name>
        <name evidence="8" type="ordered locus">AZC_0605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169136.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0605"/>
    <dbReference type="EnsemblBacteria" id="BAF86603">
        <property type="protein sequence ID" value="BAF86603"/>
        <property type="gene ID" value="AZC_0605"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0605"/>
    <dbReference type="eggNOG" id="COG1773">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091699_0_0_5"/>
    <dbReference type="OMA" id="YLGANDR"/>
    <dbReference type="OrthoDB" id="2047418at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023994">
        <property type="entry name" value="NiFe-hyd_HybE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038530">
        <property type="entry name" value="NiFe-hyd_HybE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018527">
        <property type="entry name" value="Rubredoxin_Fe_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11939">
        <property type="entry name" value="NiFe-hyd_HybE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00163">
        <property type="entry name" value="RUBREDOXIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03993">
        <property type="entry name" value="hydrog_HybE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00202">
        <property type="entry name" value="RUBREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="7">
        <location>
            <begin position="21"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="232"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="301" mass="32734" checksum="0AA6F99A89D1528B" modified="2007-12-04" version="1">MTASLRFEGSYRGQAATLDPATRLECKICWHVYDPAEGCEVWQVPPGTPFTALPDHWRCPVCDGARDQFMVLDGGAPEARPASAAAEPDVDPRLLAIARDVPGKLEAAFREIHAGQMRGVPMVNETLSVKAVGFRVHEGRVLGMLITPWFMNLILLPGPDEDWSHLATGAKDLVEFPSGFYEFLAAQRPEVGAYKACSLFSPMFDFSSMLQAVETAQAALVALFDPAHREPGVPSAEIRRRREAELAAKEAAQPKLPDLAPEGEPEAEDGAEALPQTLVPPPERSRREMIFGRSARPAGAP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMX7</accession>
    <name>QUEC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="1">6.3.4.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">7-cyano-7-carbaguanine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">PreQ(0) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Queuosine biosynthesis protein QueC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queC</name>
        <name type="ordered locus">AZC_3675</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-carboxy-7-deazaguanine + ATP + NH4(+) = 7-cyano-7-deazaguanine + ADP + H(+) + H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27982"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:45075"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the QueC family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172198.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IMX7"/>
    <dbReference type="SMR" id="A8IMX7"/>
    <dbReference type="STRING" id="438753.AZC_3675"/>
    <dbReference type="EnsemblBacteria" id="BAF89673">
        <property type="protein sequence ID" value="BAF89673"/>
        <property type="gene ID" value="AZC_3675"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3675"/>
    <dbReference type="eggNOG" id="COG0603">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081854_0_0_5"/>
    <dbReference type="OMA" id="CESCMRR"/>
    <dbReference type="OrthoDB" id="1681374at2"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01633">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000336891" description="7-cyano-7-deazaguanine synthase">
        <location>
            <begin position="1"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
            <begin position="15"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="PIRNR" id="PIRNR021494"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="349" mass="38177" checksum="6CD2EF2579134E90" modified="2007-12-04" version="1">MSKTNSGNFFEDFSLGQVIRHATPRTITEGDVALYGALYGSRFAVQSADTFAEAIGYDRAPVDDLLVFHVVFGKTVPDISLNAIANLGYAGGRFLAPVYPGDTLNAVSEVIGLRENSNGQSGVVYVRSTGFNQDGIEVLDYVRWVMVRKRDPKTPARESHVPSLPSVLAADALGDAVPPLDIDAWRFDLSGSPHRFSDYAVGEKIDHVDGMTVEEAEHMLATRLYQNTAKVHFNQFTEGQGRFGRRLIYGGHVISLARALSFNGLANAFHVAGINGGRHVSPLFAGLTVFAWSEVLEAQEISGRDDVGALRLRTIATKDRPCADFPFKPGEDYDPSVILDLDYWVLIPR</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
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        </reaction>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000000270"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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    <dbReference type="OMA" id="RIIAPDC"/>
    <dbReference type="OrthoDB" id="1632785at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="229" mass="23952" checksum="B3E46474410DBA98" modified="2007-12-04" version="1">MHIEPGLVGGTKIILSYATGAAALLYTAKLCLEAARTREPLSLLVRSLATTALVFSFFEILPHYPVGVSEVHLILGSALFLVFGAASAAVGLALGLLVQGLFFAPFDLPQYGMNVTTLLVPLFALSGLARRIIAPGTPYVDLSYRQGFALSAAYQGGIVAWVAFWAVYGQGITMSNVAAIASFGGAYLLVITVEPLLDLAVLAGAKALSGSHEGLGWRAAVARRLFQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8INW5</accession>
    <name>A8INW5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nitrile hydratase</fullName>
            <ecNumber evidence="4">4.2.1.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3798</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">NHase catalyzes the hydration of various nitrile compounds to the corresponding amides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an aliphatic amide = a nitrile + H2O</text>
            <dbReference type="Rhea" id="RHEA:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18379"/>
            <dbReference type="ChEBI" id="CHEBI:65285"/>
            <dbReference type="EC" id="4.2.1.84"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nitrile hydratase subunit beta family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.84" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172321.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3798"/>
    <dbReference type="EnsemblBacteria" id="BAF89796">
        <property type="protein sequence ID" value="BAF89796"/>
        <property type="gene ID" value="AZC_3798"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3798"/>
    <dbReference type="eggNOG" id="ENOG502Z87Q">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_106294_0_0_5"/>
    <dbReference type="OMA" id="HFKLANP"/>
    <dbReference type="OrthoDB" id="1379595at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080109">
        <property type="term" value="F:indole-3-acetonitrile nitrile hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042262">
        <property type="entry name" value="CN_hydtase_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024690">
        <property type="entry name" value="CN_hydtase_beta_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008990">
        <property type="entry name" value="Elect_transpt_acc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003168">
        <property type="entry name" value="Nitrile_hydratase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02211">
        <property type="entry name" value="NHase_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50090">
        <property type="entry name" value="SSF50090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03888">
        <property type="entry name" value="nitrile_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NHase_beta" evidence="6">
        <location>
            <begin position="1"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="245" mass="27026" checksum="5F062F6A66874F88" modified="2007-12-04" version="1">MKLQHYLGGLEGLGPVSTETRVFVEPWEKRIFGIHTAMMALSTQLSLPATPSSFRTVWTWADLRKGAESLNPLDYFRFRYYEKWIGGISSYFISHGYITEAELDALTKEYYADFSKPRPSAGCAVVDARIVQYLVEGDSPKRGAAVNHAFAVGDAVAVCDVPTVEHTRLPGYLRNRTGTVETVYEGTYTYLCNTGPDGIGAAMPVYCVRFDPVTIWPGNAEPNFAIYADLYAHYIAAPAAAQQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPP7</accession>
    <name>A8IPP7_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <sequence length="242" mass="24701" checksum="8EFD3727F2B24E73" modified="2007-12-04" version="1">MPRHALVTGASRGIGRATALRLARDGFAVSVGYAGQAIKAQEVVAEITAAGGQAIALQADIAKAADVDRMFGDAESAFGPVNVVVNSAGVLKMVSMAKASDADLAAILATNVTGAFNVLRAAANRVPDGGRIISLSTTVVATAFPNYGLYSASKAAVDLFTRTLANELRGRNICVNAVAPGPTGTELFFEGKSEELVERLAKAPPLERIATPEEIAAVIAFLAGPDGGWVNGQIVRANGGLA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
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        <location>
            <begin position="25"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF86764.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="388" mass="40122" checksum="0BF2901EAB5A1768" modified="2007-12-04" version="1">MSDGLNPFEFRTVPAIQLEWSGAKRLGEVVGARFAARKALLVTDGGLVKAGIIAPIVASLEASGFAVTLFDEVVADPPEHVLLACVAKAKAAGVDIVIGLGGGSSLDVAKLAAVLLVSEQPLADLYGIGKVQGSRLPLIQVPTTAGTGSEVTNITILTTGETTKMGVVSPQLYADFVLLDGELTVGLPAVHTAATGIDAMVHAIEAYTSRHKKNPVSDALAREALRLLSANLIAACKDGTNRKAREAMLLGAMLAGQAFANSPVAAVHALAYPLGGHYHVPHGLSNALMLGPVLRFNAKAAAPLYAELADVIAGPGAGGAEARADVFVATMQKLMDESGAPRRLRDVGVTDNTLAMLASDAMKQTRLLVNNPVEVTEADALALYREAF</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="61"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="275" mass="31043" checksum="5D02143F18311DB8" modified="2007-12-04" version="1">MTQNGFVNIFWGPCRAFRAWRAVFRVELSLLRMDPRRRSDSTEKGAAAANDAAAPVSAAPGTVTMQLYHRLREDIIRGALAPGQKLKIDELCRSYEVGSSPLREALNLLTSFGFVERLEQRGFQVKPISADEYDDIVRCRCWIEERALREAIAHGDGAWEEDVTLALFRLDRAARVRHAAIDPEWEKLHHAFHMTLLAPCGSSILMEYCEHLFTQSIRYRQIAGLLELSVRDPQAEHAEIAKAVLERDADAAVALLCAHYRRTQDALKEKLFAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQE2</accession>
    <name>A8IQE2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutathione hydrolase proenzyme</fullName>
            <ecNumber evidence="4">2.3.2.2</ecNumber>
            <ecNumber evidence="4">3.4.19.13</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase large chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="4">Glutathione hydrolase small chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0771</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>an S-substituted glutathione + H2O = an S-substituted L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:59468"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="ChEBI" id="CHEBI:143103"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>an alpha-amino acid + an N-terminal (5-L-glutamyl)-[peptide] = 5-L-glutamyl amino acid + N-terminal L-alpha-aminoacyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:23904"/>
            <dbReference type="Rhea" id="RHEA-COMP:9780"/>
            <dbReference type="Rhea" id="RHEA-COMP:9795"/>
            <dbReference type="ChEBI" id="CHEBI:77644"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:78599"/>
            <dbReference type="ChEBI" id="CHEBI:78608"/>
            <dbReference type="EC" id="2.3.2.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>glutathione + H2O = L-cysteinylglycine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:28807"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:61694"/>
            <dbReference type="EC" id="3.4.19.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Sulfur metabolism; glutathione metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Cleaved by autocatalysis into a large and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the gamma-glutamyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.2" evidence="4"/>
    <dbReference type="EC" id="3.4.19.13" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169302.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0771"/>
    <dbReference type="MEROPS" id="T03.025"/>
    <dbReference type="EnsemblBacteria" id="BAF86769">
        <property type="protein sequence ID" value="BAF86769"/>
        <property type="gene ID" value="AZC_0771"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0771"/>
    <dbReference type="eggNOG" id="COG0405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014813_3_2_5"/>
    <dbReference type="OMA" id="DGQVQWN"/>
    <dbReference type="OrthoDB" id="803717at2"/>
    <dbReference type="UniPathway" id="UPA00204"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036374">
        <property type="term" value="F:glutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102953">
        <property type="term" value="F:hypoglycin A gamma-glutamyl transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103068">
        <property type="term" value="F:leukotriene C4 gamma-glutamyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006751">
        <property type="term" value="P:glutathione catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043138">
        <property type="entry name" value="GGT_lsub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000101">
        <property type="entry name" value="GGT_peptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043137">
        <property type="entry name" value="GGT_ssub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00066">
        <property type="entry name" value="g_glut_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="528" mass="56635" checksum="E6310AA5ABC7720C" modified="2007-12-04" version="1">MRNFFKTGRSTVFARNAAVATSHPLSSLAALDMLRAGGNAVDAAITAVAVQCVVDPHMTGIGGDCFVLYTPKGASAPIALNGSGKAPAAANVDWFIEQGITEIPLDSPHAVTIPGAIAAWTKLLADHGTRSLADVLAPAIRLAEEGYVVQPRVARDWAQYAHRLQRDAVSVEIFLPGGKAPGQGDVHRQPKLAATLRKIAEGGRDAFYTGEVAEDAVARLKELGGLHTLEDFAAAEAEYVTPVTTNYRGYDVYECPPNGQGLGVLMMLNALEGYDLSPDALGEADRIHLFAEINKQVYHHRDHLFADPVQASVPVAELLSPEWAAFARSRVDMAKAADPIVWPKVAHTDTVYLCVVDKDGNAISLINSIFHQFGSCITAPKSGFLLHNRGAQFRLIKGHPNAIGPSKRPLHTIIPGMVMKDGKTVAPFGVMGGQYQTMGHVELLTNIIDRGMDVQQAMEAPRSFAYNGALELEPEYEPGLLDEMLKRGHAAKWSADPLGGAQMIWIDQETGILAAGSEPRKDGMALGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQG3</accession>
    <name>A8IQG3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative cysteine rich repeat domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0779</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0779"/>
    <dbReference type="EnsemblBacteria" id="BAF86777">
        <property type="protein sequence ID" value="BAF86777"/>
        <property type="gene ID" value="AZC_0779"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0779"/>
    <dbReference type="eggNOG" id="ENOG5032SBX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_119064_1_0_5"/>
    <dbReference type="OMA" id="ADITANC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001893">
        <property type="entry name" value="Cys-rich_GLG1_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00839">
        <property type="entry name" value="Cys_rich_FGFR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="158" mass="16510" checksum="F7B15DB768F91CAF" modified="2007-12-04" version="1">MFLFTHLLHPYRVLDAGVFMVKFRTWLVAGLLVAAASGAQAQTMSYQQAGALLAKSCGPDIMKYCADVNLGGGKLLGCLDANASKVAPKCKSDFAAAKASIGKRIAAQQAIFKVCNADAARLCQGVVPGDGNLINCLVDASKAVSKACNQTITDAGWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQI8</accession>
    <name>A8IQI8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Chitooligosaccharide deacetylase</fullName>
            <ecNumber evidence="6">4.1.1.97</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ordered locus">AZC_0788</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2</text>
            <dbReference type="Rhea" id="RHEA:26301"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="4.1.1.97"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; urate degradation; (S)-allantoin from urate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.97" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169319.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0788"/>
    <dbReference type="EnsemblBacteria" id="BAF86786">
        <property type="protein sequence ID" value="BAF86786"/>
        <property type="gene ID" value="AZC_0788"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0788"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3195">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029940_2_0_5"/>
    <dbReference type="OMA" id="GQRHWNM"/>
    <dbReference type="OrthoDB" id="1777613at2"/>
    <dbReference type="UniPathway" id="UPA00394">
        <property type="reaction ID" value="UER00652"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000255">
        <property type="term" value="P:allantoin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd10977">
        <property type="entry name" value="CE4_PuuE_SpCDA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017580">
        <property type="entry name" value="OHCU_decarboxylase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
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    <dbReference type="InterPro" id="IPR017625">
        <property type="entry name" value="PuuE/SpCDA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="SSF158694"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03164">
        <property type="entry name" value="UHCUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03212">
        <property type="entry name" value="uraD_N-term-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0536">Nodulation</keyword>
    <keyword evidence="9" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="13">
        <location>
            <begin position="72"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00020071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAF86786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="479" mass="53343" checksum="BE62F1B19C3250C3" modified="2007-12-04" version="1">MPAPASDYPRDLIGYGRNPPHPRWPGEARICVQFVINYEEGAERCLLHGDTESEAFLSDISSAQPWPGQRHMNMESIYEYGARAGFWRLHRLFTARNMPVTVFGVAKALERNPEAVAAMNEAGWEIASHGLRWIDYRNLSAETERAHIAEAVRIQNEVAGERPLGLYQGRTSENTLPLTIAEGGFLYSADTYADELPYWIESERGPFLMVPYTLEANDMRFAIPEGYASGDDFFAYLRDSFDLLYAEGETAPRMMSVGLHCRLVGRPGRAQGLARFLDYIAGHERVWVARRLDIARHWVAHHPPKGGYVPSRLSRPLFVERFGSIIEHSPWIAETVYDTGLTPAHDTAEGLQAALVAVLRAASPDRQLAVINAHPDLAGRLAAAKLLTPDSTDEQASAGLDALTAEEKARFTALNDAYRQKFGIVFIMAVRGRSKAEILDAFERRLAHDVAAEHAEALAQIERICLLRLQQILPSRGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQJ1</accession>
    <name>A8HQJ1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nitrogenase protein alpha chain</fullName>
            <ecNumber evidence="10">1.18.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">nifD</name>
        <name evidence="12" type="ordered locus">AZC_1040</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>16 ATP + 16 H2O + N2 + 8 reduced [2Fe-2S]-[ferredoxin] = 16 ADP + 6 H(+) + H2 + 2 NH4(+) + 8 oxidized [2Fe-2S]-[ferredoxin] + 16 phosphate</text>
            <dbReference type="Rhea" id="RHEA:21448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17997"/>
            <dbReference type="ChEBI" id="CHEBI:18276"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="1.18.6.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[7Fe-Mo-9S-C-homocitryl] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30409"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[8Fe-7S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21143"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the NifD/NifK/NifE/NifN family.</text>
    </comment>
    <dbReference type="EC" id="1.18.6.1" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169571.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="SMR" id="A8HQJ1"/>
    <dbReference type="STRING" id="438753.AZC_1040"/>
    <dbReference type="EnsemblBacteria" id="BAF87038">
        <property type="protein sequence ID" value="BAF87038"/>
        <property type="gene ID" value="AZC_1040"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1040"/>
    <dbReference type="eggNOG" id="COG2710">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025876_1_1_5"/>
    <dbReference type="OMA" id="CGQYSWA"/>
    <dbReference type="OrthoDB" id="363662at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016612">
        <property type="term" value="C:molybdenum-iron nitrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018697">
        <property type="term" value="F:carbonyl sulfide nitrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016163">
        <property type="term" value="F:nitrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01976">
        <property type="entry name" value="Nitrogenase_MoFe_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000510">
        <property type="entry name" value="Nase/OxRdtase_comp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010143">
        <property type="entry name" value="Nase_comp1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000318">
        <property type="entry name" value="Nase_comp1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005972">
        <property type="entry name" value="Nase_Mo-Fe_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43457">
        <property type="entry name" value="PTHR43457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00148">
        <property type="entry name" value="Oxidored_nitro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01862">
        <property type="entry name" value="N2-ase-Ialpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01282">
        <property type="entry name" value="nifD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00699">
        <property type="entry name" value="NITROGENASE_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00090">
        <property type="entry name" value="NITROGENASE_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="8 9" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_nitro" evidence="11">
        <location>
            <begin position="67"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF87038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="500" mass="56120" checksum="798405F8488BAB14" modified="2007-12-04" version="1">MSVSQPQTVEEIKARNKELIAEVLQVYPEKTAKRRAKHLNVHEAGKSDCGVKSNLKSVPGVMTIRGCAYAGSKGVVWGPIKDMIHISHGPVGCGQYSWAARRNYYIGTTGIDTFVTMQFTSDFQEKDIVFGGDKKLAKIMDEIQELFPLNNGITVQSECPIGLIGDDIEAVSKVKSKEYDGKTIVPVRCEGFRGVSQSLGHHIANDAVRDWVFDKLDPNAPPRFEPSDYDVAIIGDYNIGGDAWSSRILLEEMGLRVIAQWSGDGSLAELEATPKAKLNVLHCYRSMNYISRHMEEKYGIPWCEYNFFGPSKIAESLRKIAGFFDDKIKEGAERVIAKYQPLMDAVIAKYRPRLEGKTVMLYVGGLRPRHVIGAYEDLGMEVVGTGYEFAHNDDYQRTAQHYVKDGTIIYDDVTGYEFEKFVEKIQPDLVGSGIKEKYVFQKMGVPFRQMHSWDYSGPYHGYDGFAIFARDMDMAINSPVWKMAKAPWKQAPKPSLLAAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRT0</accession>
    <name>RPPH_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA pyrophosphohydrolase</fullName>
            <ecNumber evidence="1">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">(Di)nucleoside polyphosphate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rppH</name>
        <name evidence="1" type="synonym">nudH</name>
        <name type="ordered locus">AZC_4090</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nudix hydrolase family. RppH subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172610.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HRT0"/>
    <dbReference type="SMR" id="A8HRT0"/>
    <dbReference type="STRING" id="438753.AZC_4090"/>
    <dbReference type="EnsemblBacteria" id="BAF90088">
        <property type="protein sequence ID" value="BAF90088"/>
        <property type="gene ID" value="AZC_4090"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4090"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087195_3_0_5"/>
    <dbReference type="OMA" id="PCVGIML"/>
    <dbReference type="OrthoDB" id="1345242at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03671">
        <property type="entry name" value="Ap4A_hydrolase_plant_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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            <begin position="47"/>
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    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00298"/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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    <dbReference type="STRING" id="438753.AZC_4120"/>
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        <property type="gene ID" value="AZC_4120"/>
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    <dbReference type="KEGG" id="azc:AZC_4120"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_4181"/>
    <dbReference type="EnsemblBacteria" id="BAF90179">
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        <property type="gene ID" value="AZC_4181"/>
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    <dbReference type="KEGG" id="azc:AZC_4181"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <property type="entry name" value="ABC_transpt-bd"/>
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        <property type="entry name" value="TAT_signal"/>
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        <property type="entry name" value="ABC_sub_bind"/>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="BAF90216.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="340" mass="36664" checksum="F4B8D5F7693FFFF0" modified="2007-12-04" version="1">MTGPVLDRRSLLSLGVGAGAALTLPRAARAADDRTYKILMLTFRGETEAERGFRDLLDTAGLKTEIISRDARRDIANLPRMLADLDTLKPDLIYTWGTPVTLGVVGPYDSQDPKYIRDIPVVFALVSAPVQARIAPSFASSGRNVTGAVHVVPTDVQMKAMQSYMEFSTIGILYSETEQNSVVIVREVEAFAKANGAKVIARPFKTDASGRPTADGVEQMVTQLRADKADWLYLLPDTFLGTIYDRVTPAALAAGMPTFGAAELAIREGGALVGLVSRYYSVGQLAGTKAVEILSQGTPPSRIPIETLKRFSLVINMRVAKSLGIYPPIAMLNYAELVTG</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        </location>
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                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <sequence length="357" mass="38568" checksum="DC100D8E7C6015E7" modified="2007-12-04" version="1">MPSEGRQALQPRKDDPMSAMQTPFPTRPFGRTDMAITRVGFGAWAIGGPDWAVGWGAQDDSASVAAIRHAVSRGINWIDTAAVYGLGHSEEVVAAALKDIPLSERPYVFTKAGLVWDEADRTALPKRIGKAESIKREVEASLKRLQVERIDLYQMHWPAQDGSPIEEYWQAFLDLKQEGKVRAVGLSNHSVEQLERAEALGHVDTLQPPFSAIRRDAGAAEIAWCHAHGTGVIVYSPMQSGLLTGRFTAERAAQLPADDWRSRNAEYQGENLTRNLKLADALKPIAARHNSSVAAVAVAWTLAWPGVTGAIVGARSPDQVDGWLDAATLELTADDLSEIAKAIETTGAGTGPIRLAA</sequence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4460"/>
    <dbReference type="EnsemblBacteria" id="BAF90458">
        <property type="protein sequence ID" value="BAF90458"/>
        <property type="gene ID" value="AZC_4460"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4460"/>
    <dbReference type="eggNOG" id="COG4133">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_5"/>
    <dbReference type="OMA" id="GITHLPF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015439">
        <property type="term" value="F:ABC-type heme transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005895">
        <property type="entry name" value="ABC_transptr_haem_export_CcmA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43499">
        <property type="entry name" value="PTHR43499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01189">
        <property type="entry name" value="ccmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="18"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="221" mass="23194" checksum="A994C18A82BCD286" modified="2007-12-04" version="1">MNQLEMPSAGGANTAPILHAQGLSCQRGQRKLFSRLSFEMQAGHALIVVGPNGAGKSSLLRIVAGLLTPTEGNVALRGTDPDLSLKEQLHYLGHDDALKGALSVRENLSFWRDVLGATGLSPADALEEVGLGGLDRLPASVLSAGQKRRLAIARLLVSKRLLWVLDEPTTALDVTAQARFAELARDHLSCGGLILAATHTPLDFGPNVSELRLGKAATGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWS2</accession>
    <name>A8HWS2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">DNA polymerase I</fullName>
            <ecNumber evidence="3 13">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">polA</name>
        <name evidence="19" type="ordered locus">AZC_4464</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Single-chain monomer with multiple functions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 13">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3 13"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4464"/>
    <dbReference type="EnsemblBacteria" id="BAF90462">
        <property type="protein sequence ID" value="BAF90462"/>
        <property type="gene ID" value="AZC_4464"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4464"/>
    <dbReference type="eggNOG" id="COG0258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0749">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004675_0_0_5"/>
    <dbReference type="OMA" id="NRPPMPD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
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        <property type="entry name" value="DNA_pol_A"/>
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        <property type="entry name" value="DNA_pol_A_exo1"/>
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        <property type="entry name" value="DNAPOLI"/>
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        <property type="entry name" value="HhH2"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
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    <dbReference type="SUPFAM" id="SSF56672">
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="16">
        <location>
            <begin position="30"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="15">
        <location>
            <begin position="411"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuclease" evidence="17">
        <location>
            <begin position="431"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="18">
        <location>
            <begin position="774"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="347"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011541"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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            <dbReference type="ARBA" id="ARBA00024632"/>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
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            <dbReference type="RuleBase" id="RU004460"/>
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    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00474"/>
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    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00475"/>
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    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="BAF90462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1020" mass="110962" checksum="42EC3EECB1683211" modified="2007-12-04" version="1">MFLRRGSGIVRAASTDGPMSSAPRPIQPGDHVFLVDGSSFVFRAYFQSINQDRKYNYRSDRLPTGAVRLFCTKLFQFVRDGALGIRPTHLAIIFDKSEDSFRKELYPLYKANRSDPPDDLIPQFPLMREAVKAFGLIPVEQARYEADDLIATYARQAQAAGADVLIVSADKDLMQLIGERVAMYDPASGESGGRGSRPERRIGVPEVVEYFGVGPEQVVDVQALAGDSTDNVPGVPGIGIKTAATLIKDYGDLDTLLARASEIKQEKRRQSLIEHADKARISKELVKLVTDVPLEVPLADLVLEQPDGKQLVSFLKAMEFTTIVRRAAEAFGVEAAEIDPDPRLAVSGSGPLFAGQSAPVSTPPEADTDTAPPAPPAVALTGARPNVLEPADLAATRAQEARATKVDRSHYRMLTSLDELKAWCAKARDQGFVAFDTETTSLDPMQADLVGVSLALAPNEACYIPLAHVGAGDGLFTEGLLPGQIPFNDALAALKGMLEDGGTLKIGHNVKYDAAVLARHGITVAPYDCTMCMSYALDAGRGGHGMDELSIKYLGHTPIAFTEVAGKGKSQITFDRVPLEAATAYAAEDADVTLRLWRVLKPRLPSEGMTTVYETLERPLIAVLARMEARGISIDRATLARLSSEFAQGAARLEDEISGLAGEKINVGSPKQIGDLLFGKMQLPGATKTPTGAWSTKANVLDELAEAGHELPQKILAWRQLSKLRSTYTDALPNYVNPTTHRVHTSYALAATTTGRLSSSEPNLQNIPIRTEEGRRIRRAFVAVPGTKLVSADYSQIELRLLAEIAEIPALRQAFRDGIDIHAMTASEMFGVPVEGMPSEVRRRAKAINFGIIYGISAFGLANQLGIPRDEAGQYIKRYFERFPGIRAYMDETRAYCREHGYVETLFGRRCHYPDIAASNPSIRAFNERAAINARLQGTAADIIRRAMIRMEGALADAGLSARMLLQVHDELVFEVPDAEVEATLPVVRRVMETAARPAVELAVPLQVEARAADNWEEAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXE0</accession>
    <name>A8HXE0_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
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    <gene>
        <name evidence="1" type="ordered locus">AZC_1490</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170018.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1490"/>
    <dbReference type="EnsemblBacteria" id="BAF87488">
        <property type="protein sequence ID" value="BAF87488"/>
        <property type="gene ID" value="AZC_1490"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1490"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_2_10_5"/>
    <dbReference type="OMA" id="DFWINNA"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="247" mass="25473" checksum="29257F73CC77C6CD" modified="2007-12-04" version="1">MTLDFNGRTVAVSGAGIGFGRAISRLFADAGAQVFGCDILAAEEPVPGVEMARVDLLDRAAGAAWISGIEQKTGRALDVLVCNAGGVAGQAGKPVEDVSDAEWDRVVDVNLNAAFTLCRAVAPAMKKAGQGAIVTITSGAALQASLTGVQAYCASKHAMLGLTRQLAHELGPFGIRVNSVAPGFVRTNPATERQWAAYGAEGQRRLVEGIALKRLGTAEEIAKVVLFLASDLASFVNGQVLPVDGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXK3</accession>
    <name>A8HXK3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Twin-arginine translocation pathway signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1511</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        </source>
    </evidence>
    <sequence length="598" mass="63285" checksum="F12E0E8542B4DC28" modified="2007-12-04" version="1">MGTVFLSDLVLLVGSALVLLGTVSSLLAARFGAPILLVFLLLGILAGEAGPGQIHFSDYWATYMVGSAALAVILFDGGLRMRASTMRGAVVPAVILSTVGVMLTAGLVALAALPLLGLPPLESLLVGAIVASTDAAAVLFLVRAQGLRLGRRVGAVIEIESATNDPAAVFLTVTLVELLASGAGNPGWALTVGLVQQMVLGAALGVAGGFGLAFVLNRLDLPGGLHPALVVAAAVLIYAATAMLHGSGFLAVYLAGLVLGNRPVRAIASITSFHDTVTWLCQIVMFVMLGLLLSPSRMVQYLPPALLIAAFLVLVGRPVAVFLCLWPFRFNWREKAFISWAGLRGAVSIFLATIPMLAQLPNAEAYFNVAFVVVLVSLILHGWSLVFAARRLDVALAEPAREAKRFEIDLPGQSEHELVAYPVTGDTLAISSGLLPLWARLVFVVRRGQVLSPQEAGVLKSGDYAYILAPPRRVHRLDPLFMPEERVPSETVAGFPFSGEVMVGDVADLYGLSVPQDERAVSIADTFADRSDERPLPGMRFPLGNAAMEALEVEEGRVTQAALRFETLGEEGDSLLTRVRRQIRRRAATAEEGASPGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYN5</accession>
    <name>A8HYN5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative D-lactate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4481</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173000.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4481"/>
    <dbReference type="EnsemblBacteria" id="BAF90479">
        <property type="protein sequence ID" value="BAF90479"/>
        <property type="gene ID" value="AZC_4481"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4481"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_3_0_5"/>
    <dbReference type="OMA" id="RACNAYS"/>
    <dbReference type="OrthoDB" id="1188552at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="49"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="470" mass="50232" checksum="951A98A8433A4125" modified="2007-12-04" version="1">MLGAAAKDSFADEAALGQALAELTARLGNKVVMSRPVREQHANVTTFLPNEPADAVVFADCIEDVQTTVRICAAHRVPVIAWGAGTSLEGHVNAPYGGVCIDLSGMNRILKINTDDLDCVIEPGVTRKRLNEELRDQGLFFPIDPGADASLGGMASTRASGTNAVRYGTMKDNVLALKVVMPNGELITTSRRARKSSAGYDLTRLFIGAEGTLGIIVEITLKLYGIPESIVAGVCSFPTITDACNTVIQTIQCGIPVARIELLDEVQVRASNAYAKLSLPETPHLFLEFHGTEAGAAEQAERFGELASENGGGPFTFAGKAEDRSKLWQARHDAYWSVLPMRPGAKAVATDVCVPISRLAECVEATKADIVEMGLVAPIVGHVGDGNFHTTLMVDVTDHADVAKAEIFMKRLVERALAMEGTCTGEHGVGEGKKKYLLAEHGAETLEAMRTLKRAFDPHNIMNPGKIVSL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYU9</accession>
    <name>HIS7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="1">IGPD</shortName>
            <ecNumber evidence="1">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisB</name>
        <name type="ordered locus">AZC_4502</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173021.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HYU9"/>
    <dbReference type="SMR" id="A8HYU9"/>
    <dbReference type="STRING" id="438753.AZC_4502"/>
    <dbReference type="EnsemblBacteria" id="BAF90500">
        <property type="protein sequence ID" value="BAF90500"/>
        <property type="gene ID" value="AZC_4502"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4502"/>
    <dbReference type="eggNOG" id="COG0131">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044308_3_0_5"/>
    <dbReference type="OMA" id="ARHGLFD"/>
    <dbReference type="OrthoDB" id="1278103at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071201" description="Imidazoleglycerol-phosphate dehydratase">
        <location>
            <begin position="1"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <sequence length="197" mass="21511" checksum="6CFE5F1693049273" modified="2007-12-04" version="1">MRQAEIVRETKETKVRLAVNLDGTGRASIATGIGFFDHMLDLLARHARFDLEVEAKGDLHVDFHHTTEDVGIVLGQAIRRALGDMRGITRYADLHLPMDETLTRVALDISGRPFLVFRTEFKVGKIGEFDTELVREFFQAFASNAGVTLHVETLYGDNAHHIAESCFKGLARALRAAVAIDPAAAGEIPSTKGALGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZN3</accession>
    <name>A8HZN3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <end position="232"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="236" mass="25575" checksum="54CA223F400074E4" modified="2007-12-04" version="1">MLLQGLRKPSMLRARCGALTVRPEAGKPLAAVSGCATIGRVWIPSPGACQMSALDPAALPVPEDDGAADHLPGLELPIIRLMGTHGHPVDLSDLSGRAVVYVYPRTARPGEPPLEGWDEIPGARGCTVQSCAFRDHLEDLRAVGIEHVFGLSAQDTEHQKEVATRLNLPFPLLSDHGLQLARAIRLPTFEVGGLKLLKRLTLVVEDGAIAHTFYPVFPPEESARQVVEFFRTYDRG</sequence>
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    <accession>A8I171</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1344"/>
    <dbReference type="EnsemblBacteria" id="BAF87342">
        <property type="protein sequence ID" value="BAF87342"/>
        <property type="gene ID" value="AZC_1344"/>
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    <dbReference type="KEGG" id="azc:AZC_1344"/>
    <dbReference type="eggNOG" id="COG0515">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000270">
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        <property type="evidence" value="ECO:0007669"/>
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        <location>
            <begin position="1"/>
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    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="1504"/>
            <end position="1719"/>
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    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="1468"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
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            <dbReference type="SAM" id="Coils"/>
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    <evidence type="ECO:0000259" key="5">
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    </evidence>
    <evidence type="ECO:0000313" key="7">
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            <dbReference type="EMBL" id="BAF87342.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1720" mass="186278" checksum="47DCCEA40FDDA11F" modified="2007-12-04" version="1">MATMNSRSHVPGVSLQGIVPAPQASYFLSNELASRLEKKATDWWSELTVTSRTSEAGIDHVHVTDAAGRDWRILLADWNTPQAYQLQVDATLSLTLGEELAEVPAFIGEQERLALAYAPRRAEPLAERPTGTADVPAFLDLALAATSTLMQVHEAGVIHGGLSPARLLVAPDGKVRLTGFAWLSAAEAGAATDLRTSGPEMAYAAPELIRTDPSPVDARTDLYALGVVLYEYLVGTLPITAASLPGWLHAHVAMEAPSARLARPDIPAIIDRILLKLISKDPKQRYQTARALHADFQRVAKTIAATGHAEDFVLARGEFAEPPKASEHLVGRRRELRTLTDLYAAFRTASHQRIVLVSGEPGAGKSTLVQALLTTLDDTSVLRASGKGVQIRQGTPFAPIAQALRTALAQLMGGDERALEDARRRLSAVTGSGRALAELVPDLAILPSEPQALADVPAHLAQTRAARIIAETFAALASEASPLVLFLDDLQWFDHASLNVVRQMCSDTPAHVFLIGSFRTEAENRKTVRELLETARSSPAFAQELNLEPLLERDTTELVAFILKSKPEDVRPLSLRVHSETRGNPFYVGQLLRRLQDEHVLQFDADRQQWIWNDPHRGHPREIAELMPERVNALPAPQRSFLQRCASLGGRCSVLFAAQLSGASVAETVRAANALVAAGLLARAGADFAIAHDRVLEAAYATMSSVQRARKHLGNARALSASHPDPDPDVAFDIAAQIEHCDPNDLAPDERPRFAQALLLAARTCRSAGEAHRALHFMELIRRILVAADGDSLAALAFATEWLQCDCLLALGRVDEALAGMDALARLSPDPISTADVYRLKAFALTVKNAYTLAIEAALAGLRALDLELDPAPGRPDLDAAYAACQTRLDALGMDELIALPEMTDRRARSTLALLSTLISSFFVKGELRLLHVIKIMELTLAHGSAPESAYGLAWFGVLSAHYFGAYEQGVAYATAACTLARRDGYEAQRTAALIALDQVSVWTQPMRTALSHAREGARVGQAAGDLGMTCYARNHIASDMLVIGTRLDRVCSELMDSISMTRDIGYRDIELILIAQLNLAEALSAGEAAETTTHAELLQSSVATQFWVKHYDGLQAFFLGEMEAATGRLEEAEAMAWAAPAHIDTANNSFFLALAHAQWQEPERMAAVRLERMAAARERFRSWARLNPETFSPKHLLLEAEAARLEDRRGEAMALYERAAAAAATANFIHDQALAQELAGHFYRGLDLSAPAQGCFQAAVRGYREWGAQAKAARLAEHLTVPSGIDGPVTAPKGIQQELDLTVMTAASQTLAEEVGLEQVIRTLMKSMLIHAGAQFGLLLLLRQGEPVVEAVARVRSQDICIELQPAAKPEELMPASVLKTVMRTARPITLADAAMEAAQRGLSMGGRSIRSLACIPLIKRGELIGMLHLENALSADVFTPRRMAMLEVLAPQAAISLDAARLYGDLMDENLRRAQAEFELREARSELAQANQLTAMGSFATSIAHEINQPLATLVAHAEAGLRWLNRPEPDLGEVTKSLQSISQAGRRAADIITALRALVKQAPAPLTLVTIEDVLDEVLKIVCADLKTNGIQLSLALSTERHAILVNNIQLQQVLFNLITNAVQAMANAATPERHLRISTAIVQDNVEVTIEDTGCGMSQEVIARIFQPFFTTKTTGMGVGLAICRSIMERHGGTLEARSIEGKGSTFFVRIPLAPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8I277</accession>
    <name>A8I277_AZOC5</name>
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        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
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        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
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    </protein>
    <gene>
        <name evidence="8 11" type="primary">rho</name>
        <name evidence="11" type="ordered locus">AZC_4715</name>
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    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173234.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4715"/>
    <dbReference type="EnsemblBacteria" id="BAF90713">
        <property type="protein sequence ID" value="BAF90713"/>
        <property type="gene ID" value="AZC_4715"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4715"/>
    <dbReference type="eggNOG" id="COG1158">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016377_4_3_5"/>
    <dbReference type="OMA" id="TRLCRAH"/>
    <dbReference type="OrthoDB" id="1619125at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
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        <property type="project" value="UniProt"/>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:DNA-templated transcription, termination"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
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        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
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    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="10">
        <location>
            <begin position="51"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="174"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="186"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
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            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF90713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="423" mass="47234" checksum="108C6EA428D8FB54" modified="2007-12-04" version="1">MREVKLQDLKSKTPVELLAFAEENQVENASTLRKQELMFAILKQLAATETDIIGTGVVEVLQDGFGFLRSPDANYLPGPDDIYVSPSQIRRFGLRTGDTVEGQIRSPKEGERYFALLKVNTINFEDPEKTKHKINFDNLTPLYPDERLKLEVEDTTGTKKDFSARIIDTVSPIGKGQRGLIVAPPRTGKTVLLQNIAKSITANHPECFLIVLLIDERPEEVTDMQRSVKGEVISSTFDEPASRHVQVAEMVIEKAKRLVEHGRDVVILLDSITRLGRAYNTVVPSSGKVLTGGVDANALQRPKRFFGAARNIEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNSEVILDRKVSDKRVFPAIDITRSGTRKEELLVPADVLKKMYVLRRILNPMGTVDAIEFLMDKLRQTKTNQDFFDSMNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2G0</accession>
    <name>A8I2G0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1868</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170396.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1868"/>
    <dbReference type="EnsemblBacteria" id="BAF87866">
        <property type="protein sequence ID" value="BAF87866"/>
        <property type="gene ID" value="AZC_1868"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1868"/>
    <dbReference type="eggNOG" id="COG4172">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_86_2_5"/>
    <dbReference type="OMA" id="MADRYTF"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="entry name" value="Peripla_BP_I"/>
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            <end position="361"/>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87882.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="382" mass="39897" checksum="67FCA46B97F04D72" modified="2007-12-04" version="1">MKLQALALGAAILVLPLTGSLAQEIKLGATLSTTGPAASLGIPMKNTLQILPKEIEGVPVSWTILDDGTDTTQARRNAEKLASENVDLIIGGNTTPTSLATVEIAGRTQTPVLAIAPSPGIIEPVEGAKTWVFKVPLGERELAERTLASMSQRGVKTIGFIGFNDALGEGWLKEFERFAPKFGITISAVEKFARTDTSVVAQALKVLAARPDAVFVGATGTPAVLPTAQLRERGYKGLIYQASGVVNNDFLRVGGKNVDGVLIAAGPLLVASALPDANPSKATSLDFVKLYEATYGPGSASLFAGNAYDAWLLIRNAMSSALKVAKPGTPEFRAALRSALEKTDGLAVTNGVITFGPNNHGIFPPGTPVMLTVRNGTWALAN</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <feature type="binding site" evidence="4">
        <location>
            <begin position="37"/>
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        <ligand>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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    </evidence>
    <sequence length="245" mass="26115" checksum="F0A66A9F66471784" modified="2007-12-04" version="1">MSPLLAINDLRVGYGQVEALFGASLTVAPGTIVTVVGPNGAGKSTLLNAVAALIPKRSGRIAFAGQNTDGLSTEELAACGMALVPERRDLFGSMSVEDNLLLGAYLRRSNHKAIADSLEEIFARFPRLKERRAQEAGTLSGGERQMLAIGRALMCRPRLLLLDEPSLGLAPQIVRNVFDVIDSLRATGVSVLLVEQNAQMALRIADYAYVLETGEIVNQGTGAALLHDPRVMETYLGIGHGSYAD</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Hydrolyzes indole-3-acetamide (IAM) into indole-3-acetic acid (IAA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1973"/>
    <dbReference type="EnsemblBacteria" id="BAF87971">
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        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="468"/>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="492" mass="51691" checksum="48A2320740255F87" modified="2007-12-04" version="1">MNFALMLTMGHAPCEQADLEKDGVKSITVAEQSLPTWASAADLARRIATRACTASAAVEEHLARIAALEPHLKAFITVDADGARRRARELDVSPQRQGPLHGLPVAIKDLTRTRGLRTTFGSRAFAGEVPEADDPVVARLRRAGAVIIGKTNTPEFGFGAVCVNDLQGPTANPYDLVLTSGGSSGGSAVAVATGMSALAHGTDFGGSVRTPASFCGVVSIRPAIGVIADPDRELGWTGLATHGAMGRSVADAALLLQAMAAPNAYDPLSTALAAGPDAPPRRVAVTPDFAVAPVCKAVRRRFARAVDEMRAVVGEVVEATPDCAGAPLAFRTLRAAQIARTYGAFVDGNVPVSPTVRWNVEAARSLTAQDYLAAEAARTALWRRFTRFFEQYDVLVTPAASVLPWPNAEGERMEMDGRSLADILDYLTITFIVSLVGFPVVTLPAPRQPGEVPFGLQLIGRPGAEAALIALAARLEGEAGFCWSPPPSVSML</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterotetramer composed of ParC and ParE.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170534.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2007"/>
    <dbReference type="EnsemblBacteria" id="BAF88005">
        <property type="protein sequence ID" value="BAF88005"/>
        <property type="gene ID" value="AZC_2007"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2007"/>
    <dbReference type="eggNOG" id="COG0188">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002977_4_1_5"/>
    <dbReference type="OMA" id="PRSNRID"/>
    <dbReference type="OrthoDB" id="217468at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019897">
        <property type="term" value="C:extrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00936">
        <property type="entry name" value="ParC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005742">
        <property type="entry name" value="TopoIV_A_Gneg"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="6">
        <location>
            <begin position="16"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="47"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="5">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="5">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="745" mass="82316" checksum="6D49BF971300F489" modified="2007-12-04" version="1">MATKTLPPGGGSVEPVDLKAALEERYLAYALSTIMHRALPDARDGLKPVHRRILHAMRQLKLDPGSGFKKCARVVGDVIGKFHPHGDQAVYDALVRLAQDFAQRYPLVDGQGNFGNVDGDNAAAMRYTEARLTETARLLLDGIDDDAVDFRPTYDGSEEEPVVLPAAFPNLLANGSQGIAVGMATSIPPHNAAELLDASLHLLEHPNAPASDLLQFVPGPDFPTGGILVEDPVGTAEAYATGRGAFRVRARWHKEETGRGTYVVVVTEIPYGVPKSRLVEKIAELLTDKKLPLLADVRDESAEDIRLVLEPRARTVDAEVLMESLFKLTELESRVSLNMNVLVRGQVPKVLSLADALREWLDHRREVLLRRSRNRLSQIAHRLEVLGGYLIAYLNLDEVIRIIREEDEPKVELMRTFELTDLQAESILNMRLRSLRRLEEMELRKEHAALTKEQEQLNKLVASEAAQWKAIGKEIRETRKTYGPDTEIGRRRTDFAVPPDVHESAFTEALVEREPITIVMSAKGWIRALKGHVADVTGVPFKGDDTLAHAFYAETTSKIMVLSSNGRFFTLDAAKLPGGRGHGEPVRLMIELEQEAEIVSVFAHRPGGKLIVASREGRGFVVAEDDCLANTRKGKQVLGVDAPDAAVLAVPADGDTVAVIGDNRKLLLFPIAQVPEMTRGRGVRLQRYKEGGLSDLKVFNRADGLTWEDSSGRTWTVTELLDWQGERASSGRLPPKGFPRNNKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8I477</accession>
    <name>A8I477_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">1-deoxy-D-xylulose 5-phosphate reductoisomerase</fullName>
            <shortName evidence="7">DXP reductoisomerase</shortName>
            <ecNumber evidence="7">1.1.1.267</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">1-deoxyxylulose-5-phosphate reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-C-methyl-D-erythritol 4-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dxr</name>
        <name evidence="11" type="ordered locus">AZC_1699</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13717"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58262"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.267"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DXR family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.267" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170227.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1699"/>
    <dbReference type="EnsemblBacteria" id="BAF87697">
        <property type="protein sequence ID" value="BAF87697"/>
        <property type="gene ID" value="AZC_1699"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1699"/>
    <dbReference type="eggNOG" id="COG0743">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035714_4_0_5"/>
    <dbReference type="OMA" id="PIDSEHF"/>
    <dbReference type="OrthoDB" id="1200722at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030604">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00183">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003821">
        <property type="entry name" value="DXP_reductoisomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013644">
        <property type="entry name" value="DXP_reductoisomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013512">
        <property type="entry name" value="DXP_reductoisomerase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026877">
        <property type="entry name" value="DXPR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036169">
        <property type="entry name" value="DXPR_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30525">
        <property type="entry name" value="PTHR30525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08436">
        <property type="entry name" value="DXP_redisom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02670">
        <property type="entry name" value="DXP_reductoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13288">
        <property type="entry name" value="DXPR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006205">
        <property type="entry name" value="Dxp_reductismrs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69055">
        <property type="entry name" value="SSF69055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00243">
        <property type="entry name" value="Dxr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DXP_reductoisom" evidence="8">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DXP_redisom_C" evidence="9">
        <location>
            <begin position="143"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="DXPR_C" evidence="10">
        <location>
            <begin position="258"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="389" mass="39669" checksum="DEB2527783B74B88" modified="2007-12-04" version="1">MTSVSILGATGSVGRSTVRVLEGERERFRVEAVAGGRDAAGLAELAIHLGAKFAAVADDAAGAELKARLAGTGIACGAGRTAVLEAAARDADIVVAGISGIAGLEPTVAAFRAGRRIGVANKECLVAAGAFFTAEAERVGAEIFPVDSEHNAIFQALSAGPRAAVEKVQITASGGPFRTAPREAIAKAGPAAALKHPNWSMGAKITIDSATLMNKGLELIEAHHLFGVPPEQLEVIVHPESIVHGLVAFEDGSVVAVLAMPDMALPIAHCLSHPGRLPTTCRKLDLAALGRLTFEAPDLDRFPCLSLALSALGEGGAAPTILNGANEVAVAAFLEGRIGFYGISAIVEETLALATRGAAPASVAEALQLDAEARRIALSLLPKFAAKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5B8</accession>
    <name>A8I5B8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="5 8">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2257</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="5 8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170784.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2257"/>
    <dbReference type="EnsemblBacteria" id="BAF88255">
        <property type="protein sequence ID" value="BAF88255"/>
        <property type="gene ID" value="AZC_2257"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2257"/>
    <dbReference type="eggNOG" id="COG2109">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088595_0_0_5"/>
    <dbReference type="OMA" id="HAMGEGF"/>
    <dbReference type="OrthoDB" id="1690483at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025826">
        <property type="entry name" value="Co_AT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12557">
        <property type="entry name" value="Co_AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Co_AT_N" evidence="9">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR015617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="206" mass="22771" checksum="0185D009087F5C36" modified="2007-12-04" version="1">MINEPIDPRDAERHRAKMAKRKAVQDAEVASKNIEKGLLIVHSGPGKGKSTAAFGLALRMLGYGRTVGIVQFIKGAWHTGEKDAFAAFGNRVKWHTMGEGFTWETQDLARDKAAAERAFDKARELMDDPAVSLVILDELNIALRYEYLDLNDVIDVLTSRRPDLHVVITGRNAKPALIEAADLVTEMQLVKHHFAAGVKAQVGIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5H7</accession>
    <name>A8I5H7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nodulation protein W</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nodW</name>
        <name evidence="5" type="ordered locus">AZC_2281</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2281"/>
    <dbReference type="EnsemblBacteria" id="BAF88279">
        <property type="protein sequence ID" value="BAF88279"/>
        <property type="gene ID" value="AZC_2281"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2281"/>
    <dbReference type="eggNOG" id="COG4566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_4_5"/>
    <dbReference type="OMA" id="EIPITHS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="17"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="218" mass="23875" checksum="35436E959A567AC5" modified="2007-12-04" version="1">MMKVQKSRKETAPATPVVIVVDDDAGLREALSSLFRSVGLEVALFASALEMLAAPLPDAPRCLVLDIRLPGVSGLDFQQQLTRQDVDMPIIFMTGHGDIPMSVRAMKAGALDFLTKPFRDQDMLDAVLAAIAMDRTRRDERAASDHVRTLYESLTEREKQIMGLVTSGLMNKQVAAEVGLSEITVKIYRGNVMRKMAARSFADLVRMAEAVGLSKPKA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5Q2</accession>
    <name>QUEA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="1">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queA</name>
        <name type="ordered locus">AZC_2308</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the QueA family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170835.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I5Q2"/>
    <dbReference type="SMR" id="A8I5Q2"/>
    <dbReference type="STRING" id="438753.AZC_2308"/>
    <dbReference type="PRIDE" id="A8I5Q2"/>
    <dbReference type="EnsemblBacteria" id="BAF88306">
        <property type="protein sequence ID" value="BAF88306"/>
        <property type="gene ID" value="AZC_2308"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2308"/>
    <dbReference type="eggNOG" id="COG0809">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039110_1_1_5"/>
    <dbReference type="OMA" id="YSYGDGM"/>
    <dbReference type="OrthoDB" id="368001at2"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000071335" description="S-adenosylmethionine:tRNA ribosyltransferase-isomerase">
        <location>
            <begin position="1"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <sequence length="354" mass="38051" checksum="30E9E98A12EAB561" modified="2007-12-04" version="1">MRVDAFDFDLPPERIALRPAEPRESARLLRVRPGAAPELEDRTIADLPDLLQPGDALVVNDTKVIPARLDGTRTRAGGSTVAIEATLIRRLSGSAWAAFAKPAKRLAVGETVVFAGASGGTLEARVLDKLESGEVHFAFALSGPELDAAIDAIGHMPLPPYIAAKRPEDDRDRTDYQPVFARVEGSVAAPTASLHFTPDLLAKIAARGVSRYTVTLHVGAGTFLPVKAEDTTDHQMHAEWGEVSPETAAELNAVKARGGRIITVGSTATRLIETAATPEGSIRPYLGETDIFITPGYAFRASDVMLTNFHLPRSTLVMLVAAFVGHETQKRAYAHAIASGYRFYSYGDACLLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5V3</accession>
    <name>A8I5V3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaD</name>
        <name evidence="8" type="ordered locus">AZC_2326</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170853.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2326"/>
    <dbReference type="EnsemblBacteria" id="BAF88324">
        <property type="protein sequence ID" value="BAF88324"/>
        <property type="gene ID" value="AZC_2326"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2326"/>
    <dbReference type="eggNOG" id="COG0669">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100149_0_1_5"/>
    <dbReference type="OMA" id="EFQMALM"/>
    <dbReference type="OrthoDB" id="1846503at2"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="16"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="100"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="135"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="173" mass="18485" checksum="FB1CED75CFA621E0" modified="2007-12-04" version="1">MSRPDHTRRVAIYAGSFDPPTNGHLDVVRSASRLADHLVLAVGIHPGKTPLFTADERLAMLKDICGPIAQEEGATLEAITFGDLVVNTARRVGATLLIRGLRDGTDLDYEMQMAGMNGTMAPEIQTVFLPASPRVRPITATLVRQIAAMGGEVAPFVPAEVLARLKAKFPSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5V5</accession>
    <name>A8I5V5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Homoserine/homoserine lactone/threonine efflux protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2327</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_2103"/>
    <dbReference type="EnsemblBacteria" id="BAF88101">
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    <dbReference type="KEGG" id="azc:AZC_2103"/>
    <dbReference type="eggNOG" id="COG4191">
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    <dbReference type="OMA" id="LIQLRWI"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
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        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
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            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="158"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="212"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="437" mass="47538" checksum="C070F4FFA13C5303" modified="2007-12-04" version="1">MPVAQQDTSGNKNLFLLIQLRWLAVAGQVFTILVVDVWLHIRLPLQEMISVLLLLVGLNLVALWRHRSEAEVTNVELLGELILDVAALTAQLYLSGGATNPFISLYLLQVGLGAVLLQPWSAWVLVVLTSACFVWLIGQFRPLPLPHDDHSTLFNLHIGGMFVCFLLAASLLVQFISRISANVHEREQRLAELRRKSAEEDLIVRMGLLASGAAHELGTPLATLSVILNDWQHMEAVEEDPELMEDLSEMQAQVARCKMIVSGILMSSGQARGEGTLRTTADVFFDELVDEWQESRSPAALEFVNDLPPDLPIISDVALKQVILNVFDNALEASPAWVAVSVTRAADAIVLEVRDHGPGFAPDILAEFGKPYGSTKGRPGGGLGLFLVVNVVRKLGGTVTAQNEADGASVILDLPLHALSPDVDDGDHHTPPADRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7X9</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2181"/>
    <dbReference type="EnsemblBacteria" id="BAF88179">
        <property type="protein sequence ID" value="BAF88179"/>
        <property type="gene ID" value="AZC_2181"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2181"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_5"/>
    <dbReference type="OMA" id="LPAPYCR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="307" mass="33404" checksum="817F4910563CE765" modified="2007-12-04" version="1">MDEFISVAIGISMELRTLRAFVEVVRQGGFSQAAKAVFATQSTISKAVKQLEDELGVPLLDRVGHKSRLTAAGEIVYRRAVTMLAERDDLVAELGELRGLKRGSLRLGLPPLGSDTLYAPLFALYRSRYPGIDIQLVEHGSARLEEMILAGDLDLAGSLLPITDEFEWQSVHDEPLVALVADTHPLAGAASCRLADLAASPFLFFEEGFALNKVLREACQKQGITPQIAARSGQIDFLVGLAAAGLGTAFLPRMIAEQRHHPGVARVLLDEPDTAWHMALVWRRGGYLSHAARAWLALAREVHGARN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8N4</accession>
    <name>A8I8N4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Probably FAD dependent oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="protein sequence ID" value="BAF88682.1"/>
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            <end position="346"/>
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    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF01266"/>
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    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    <sequence length="374" mass="39599" checksum="20A312A138BC17C7" modified="2007-12-04" version="1">MMHDLAVIGGGVHGSTVALFAARGGMKVTLIERGPLCREASGVNAGTLTMQMTRVALIPYALRAHAMWASAREWLGHDVGVVVCDGLSLAFTEQEEQLLSFRAGKRRDAGAPIELISGARALEVEPGVSDKVRVAGYCKVDGYANAYLTGLAFRRALIEAGVDLKENTPASGITREDGGFAVQTAQGVVRAKRIVLAGGVWIEPMMAWLGIRLPIKTLINQLVVTERVRPVMRTVVGIANGLLSLKQYPHGTVVIGGGWQGLGDRERGGVELLPDRIVGNVRLACHAIPDLKAARVARAWAGLEAETADALPAAGPIPGIPDAYVCGSVHSGYTSGPYIARLLADRILGREPALPLFPIDRLLASSAISEARND</sequence>
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        <name evidence="3" type="ordered locus">AZC_2717</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="gene ID" value="AZC_2717"/>
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            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <reaction evidence="7">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
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            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
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    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
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    <comment type="similarity">
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    <dbReference type="EC" id="1.3.1.9" evidence="7"/>
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    <dbReference type="EnsemblBacteria" id="BAF88767">
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    <dbReference type="HOGENOM" id="CLU_010194_10_1_5"/>
    <dbReference type="OMA" id="DGGLSIM"/>
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    <dbReference type="Proteomes" id="UP000000270">
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    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
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    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
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    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6 7" id="KW-0276">Fatty acid metabolism</keyword>
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    <keyword evidence="6 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="176"/>
        </location>
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    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="50"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="95"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="123"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
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        <ligand>
            <name>substrate</name>
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        <location>
            <position position="193"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00000175"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023160"/>
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            <dbReference type="PIRNR" id="PIRNR000094"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
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            <dbReference type="PIRSR" id="PIRSR000094-1"/>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
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            <dbReference type="PIRSR" id="PIRSR000094-2"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
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            <dbReference type="PIRSR" id="PIRSR000094-3"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
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            <dbReference type="EMBL" id="BAF88767.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="285" mass="30590" checksum="4AB8C3EB31CAEF77" modified="2007-12-04" version="1">MAPNLHIATHHTCVSQDVPPRPEVSMIDATQMPALEGKRALILGIANEHSIAYGCARVFRRLGAEVALTYLNEKARPFVEPLAHELDARIFAPCDVEQEGALDSVFAEVRETWGGLDIALHSIAFAPKDDLHGRLVDSSAAGFALAMDVSCHSFIRMAHLAEPLMTQGGTLLAMTYQGANKVVPNYNLMGPVKAALESAVRYLAYELGPKGIRVHAISPGPLKTRAASGLKDFDLLLNEAATRAPVHELVDIDDVGMTAAFLATPFAHRLTGMTVYVDGGLSIMA</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAE4</accession>
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    <gene>
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        <name evidence="3" type="ordered locus">AZC_2498</name>
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    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="entry name" value="HotDog_dom_sf"/>
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        <location>
            <begin position="9"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13452"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88506.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="276" mass="29937" checksum="47C4D8D3FB123AAA" modified="2007-12-04" version="1">MDIDHLRSWIGRTETVRDLLTARALREFRVTLNLPAGAPAPGEPALLTSHWCLAPPAVPMDGLGPDGHPARGGFLPPVPLPRRMWAGGRLEWHDALRVDDEVTRASRIADVVVKEGRTGVLCFVTVEHEITTARGVAVRERQDIVYRGTDAPPGGAGTGQPAPVAQWQESVETSPVLLFRYSAITFNGHRIHYDRTYCIEEEGYPGLVVHGPLQATLLAEFAGRLLGRAPQTFAFRSVRPIFDGPPMTLNAVATGEGLELWTAGTDGQPCMKAEAA</sequence>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="10" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
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        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
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        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
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    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
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    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="14"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="124"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="235"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
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    </evidence>
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    </evidence>
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            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
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            <dbReference type="Pfam" id="PF00441"/>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
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    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="390" mass="42689" checksum="1A3B352FB2AE04E5" modified="2007-12-04" version="1">MSGTIEAIDANFSDIREAVRKLCADFPGEYWRKLDRESAYPTAFVEALTHSGFLAALIPESYGGAGLPLSAAAAILEEVQRAGCNGGACHAQMYIMGALLRHGTGAQKETYLPKIASGELRLQAFGVTEPTSGTDTTALKTFAEKRGDYYVVNGQKVWTSRAEHSDLMLLLARTTPRDQVQKRTDGLSVFIVDMREAKGNGLTIRPIRAMMNHSTTEVFFDNMKVPAENLVGEEGKGFRYILSGMNAERILIAAECVGDAKWFIDKATAYAKERVVFGRPIGQNQGVQFPIAKAYAQMRAAELMVHRAASLFEAGQDCGQEANMAKMLAADASWAAAEACVQTHGGFGFAEEYDVERKFRETRLYQVAPISTNLILSYLAEHVLGLPRSY</sequence>
</entry>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171105.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2581"/>
    <dbReference type="EnsemblBacteria" id="BAF88579">
        <property type="protein sequence ID" value="BAF88579"/>
        <property type="gene ID" value="AZC_2581"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2581"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_4_0_5"/>
    <dbReference type="OMA" id="WCARTIS"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720924" evidence="1">
        <location>
            <begin position="30"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="50"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="363" mass="39090" checksum="F839C6F4FA1AA5DB" modified="2007-12-04" version="1">MKPLLGTALRFATAVCLAAAVLPTASASAADKVLVGLAIPPTITDGGVYAIADELGLFKEQNIEVESVVLQGAGAIVPQLLQKKVTFGFPLPETLLAAHKPGEPPLPLTYVYNANPYNSLELSVLASSDIKSIKDLKGGKIGVGALTWGTIPQTRALLRSEGLEPGKDVSIVAVGNLGSGFHALRENRVEALNFNSTWIDLMELEGTKARRLPYPPVFANMIVNGFLTHADTVKQQPDLIARFGRAYAQAVVACDANPKACVEAFWKRNPQAKPQGDADKALADNVEILKRRLALTVRDAQGKDRVPGAFDLEIIRAYVKAMHEYGEFATADIPLETYFSNQFVPEYSKFDRAALIARAKALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB02</accession>
    <name>A8IB02_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2589</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171126.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2602"/>
    <dbReference type="EnsemblBacteria" id="BAF88600">
        <property type="protein sequence ID" value="BAF88600"/>
        <property type="gene ID" value="AZC_2602"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2602"/>
    <dbReference type="eggNOG" id="COG4455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_087908_0_0_5"/>
    <dbReference type="OMA" id="GRYYWIP"/>
    <dbReference type="OrthoDB" id="977924at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009211">
        <property type="entry name" value="TagJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07024">
        <property type="entry name" value="ImpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029288">
        <property type="entry name" value="SciE_ImpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="266" mass="29435" checksum="14800FBB59F7D711" modified="2007-12-04" version="1">MQDTPLHLFQEGKLTDAIAAMNQQVKEKPLDIALRSQLAELLCVAGDLDRAERQFEAIAQQDPKTALQVGSLRQLLRSSQARRQVFLEGRAPDVLEEPPAHVALRLEALMHLREGRAAEAGASLAKAEELRPPLAGRHNDIGFVDFRDLDDLLGGILEVMTTTGKYFWVPMERVETLEFEAPRRMLDSAWRMAQISVRGGPQGEVAIPSTYPATGEAPSDAVRLGRETDWTEVAPDCVRGSGLRTFLVGEESLTILQLGRLEFDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBA8</accession>
    <name>A8IBA8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Autotransporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2635"/>
    <dbReference type="TCDB" id="1.B.12.5.2">
        <property type="family name" value="the autotransporter-1 (at-1) family"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF88633">
        <property type="protein sequence ID" value="BAF88633"/>
        <property type="gene ID" value="AZC_2635"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2635"/>
    <dbReference type="eggNOG" id="COG3210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_224791_0_0_5"/>
    <dbReference type="OMA" id="EFYEYQY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.20">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012332">
        <property type="entry name" value="Autotransporter_pectin_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013425">
        <property type="entry name" value="Autotrns_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12951">
        <property type="entry name" value="PATR"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02601">
        <property type="entry name" value="autotrns_rpt"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Autotransporter" evidence="2">
        <location>
            <begin position="3488"/>
            <end position="3766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="3766" mass="358281" checksum="CB18C9E7915AA30C" modified="2007-12-04" version="1">MVFEWWVGIMSARIAETMFRSQGESFRQPLLRKRLLRSSALIPFLALVLLAPPAFAGGGGNGGGNSGSPGGLDNYDAGGTGGTGTAATSIGSGGGAGGGGAGLTGGAGGAANGTNGAGGAGGTHAYVGSGSGVTNSLTGGNGAAGSSGSNNGGGGGAGGTAVVITGNSSGVLNWSSATFTLTGGVGGAGGSGSSAQNGGEGGTGGDGLYFGQDITFTSSNSLLITGGQGGAGSNGRAGGNGIEFATGTNSRATINGQVQGGAGGTSTKTNSNTGNGGNGILADTLDLTLNAMVSGGAGSSGAGDVGGGAGGDGISALAFTGMINAAVTGGTGGSTGASSSASAGSGGYGLRLNGASTVTVNANVTGGNSGAASVSGGYGGIGIYATPSLSLTIQNNAIVRGGDAGAVTGSAYTTGGSGIYLDYATSDITLLSGQVIGGNASGSDSAATGGYGIESHGAPSVTITLGAGSTISGGLGGNGMSDRSARANAIFIENFDGTPATNTLVLLGSGGTSGSTYATIIGDVVATPADSTTNKMTFGGAGGVFDVGQIDLGAGSSAATIFRGFTEFTVDTTGTWIMTGASTTGGTALPATWTVAAGTLQLGNASTAGTLLGSVGVNSGGTLANGGRTATVTNGVTVTSGATLSLTAVSGGPALSITSGNLNLNTGSTLTITLGAPTTQSLISVAAGSAVLGSTLNITDAGTMAAGSYTLLSYSGTLSGPGLTLGTTPSAFQFSVDTSSTAGQVLLLVTGGAPTVIYWNGSTTGGSSGPVAGGTGTWTAASSGVTNWTNSAGTSRVVSDPSLTAIFAGTAGTVTVSAASGAVSAKGLEFDTSGYTITGSELTLVNGSTMPQVNVVGSSASATISAPLAGSNGLEKIGDGALSLYGANTYTGNTTITAGTLTVGGAGSLGSGTYAGNISIASGTSFNYASSAAQTLSGNISGDGDLTVGGTGSLTLSGNNTYTGGTTNLNGALVASGGSAIGDTSAVLMGNSASLTISAAETIGSLAGAGTVAISGQLTLGGINTSTTYSGVISGAGGLTKTGTGTLTLGGANTFTGALNLESGTLLVNTTGSIASASSVNLSAGTQLTLSGGGSKSIKMLNDGVGGTGTAYLQLGTTALTIGLGDGSGTFSGAITGSGSLTKVGTGTLTLAGANTFTGGLQISGGTVTVTGGSAIANTANVTVGTGATLTLQASETIGALSGAGSVTATGGSRVLTAGGNNTSTTFSGTLSASGGNSIGLVKTGTGTFTLTGASSYAGGTTISAGTLQIGDGGTTGSITGNITNNAALIFNRSDDLTYSGGISGTGTLQKAGSGKLTLTGNNSMTGLTTVSAGTLALTGGMAGSVTVNSGATFASTSTGLIGGTLTIENGATLTATSGNLFTVAGLSLASGSIINLTANTPTTTAAVSVTGGLVLGGTLNVSAGTGFGSGTYRVITYGGALTNNGLALGSTSSDSLYYLNTATIGQVNLLVAVGQWWNGAVTTAGGSSVAGGNGTWDVAAATTNWTNTTGSSADAWGQGGLALFGGAAGTVTVSGPTAPQVAGLRFLTDGYTVTGGQIGLSAFATGATPAILVDTGLSATIASQLTGSDGLEKTGAGTLILTGTSSITGGTTITAGTLQIGNGGSTGSVAGNIVNNAALVFNLSSDTTYAGSISGAGTLEKTGTGTLTLSGSNATTGLTTVSAGTLALTGSLAGSVNVASGATLRGSTTGIVGGTVTIANGGTLAVASGNLFTAGALSLGSASTLAFTAGTPTTTAAVGLGGSLTLDGTLNITAGNGFSTGTYRLINYGSSFTDNGLAIGTAPTHSLYRIDTATLGQVNLVVAAGQWWNGTTTTAGGSAVVGGSGTWNVAAGTTNWTNTDGSSADAWGQGGLAVFGGTAGTVTLSGGTSPQVAGLEFMVSGYTVTGGSIGLSAFSAGTKPAIYVESGASATIASNLTGTDGLSKTGAGTLIFSGVGTYTGGTSIAAGTLQIGNGGSTGSVAGNIADDGALVFNRSNDLTFAAVVSGSGSVTQAGSGGLILTGANTYTGGTTVSSGTLQIGAGGTTGSIVGAIANSGTVAFNRSDDIVASGAITGSGSLVQMGSGKLTLTGSNSAAGGTSVAGGTLEILSGATLASNVVVGSGATLQGETGGTAGAVLNGAVTVQNGGTIRAAATGTPGLYGLSMSGLTLSNSANINVNLGANTGVAVLQATNLTLDGVLNISNTGSMALGVYRLIDYTTLVADNGLAIGTVPSQFAYSVDVVPNHVNLSVLNGSLRYWNGTTTTPDGTVHGGSGTWSSSVSPANWLTAGLNQSVPWNSEFAVFSGTPGNVSVSGTVSTTGMQFMVDGYSLGAGTIVLAATSGQTQVRVGDGTGLGASYVATLGSVIDGTTGLEKTDLGTLILTGTNTYTGNTTVSAGTLQIGNGGSAGSILGDVAVASGATLAFNRSDAVSFGGVISGNGGFTQTGSGTLTLTGNNTYTGTTTISGGTLQVGDGGTSGTLAGTVVNNAALVFNRSDATSFAGAISGTGTLTKQGAGALTLSGSNSFTGATTVAGGTLAISGGASLADGARLTVASAATLSLLDANETVGSLAGAGTVALGSQTLTAGGDNTSSTFTGTLSGTGGLTKVGTGTLTLGGTNSYSGQTTVSAGTLVAQGNAALADGTAVSVASGATLDLQMTGTKILGGLSGAGNVQLNATTLSVGGDNSSTTYSGVLSGTGGLTKTGTGTLTLSGTNTFTGTAQISSGALALMGSVGGDVSVAAAATLSGTGSVSGTVNVLSGGTLSGTQPTGLTMGGLTLASGANMNVTLGAPSGSGLFTVNGNVTLDGTLNVTQAPGFGIGIYRLASYTGTLTDNGLDVGALSGGLLGGVQTAVAGQVNLLVESPNNALLFWNGANTTPTGSIVGGAGTWTASNQTNWINGSGTIAQNWNGSFAVFQGTAGAVDVDASNGPVSASGMQFATSGYIVSGAPIVLTGSGPATLRVGDGTGAGAAMTATIASALTGTTGIVKTDLGTLILSGANTYTGGTTISAGTLQIGAGATTGSILGDVVNNAALVFNRSDATSFAGAISGTGTLTKLGSGELSLTGTNTYSGGTTIGAGTLRASSAQALGSGGLTINRGGTLRGSSSFTFGNNVVLSNAGTATTNAAISVDAGQTVNVSGVISGSGALDKTGGGTLVLTGTNTYTGTTTISAGTLQIGNGGTTGSLLSNIVNNASLVFNRADTYTFTGSITGTGSVTFLGGGTVQFSAPYTGAVGVDDSTVRLVAGTTTSSPFTVNNGGVLGGTATIGGLTVNSGGTASPGYSPGTLTVNGAVTFNAGSVYAVDLTPEGAHDLIIASGNVTLSSGATVAVNATAGVYPRSGQVTIITTSGTVIGTFGAVTSNYAFLTPSLTYDQQNVYLNYVYNGIRFSDYARTPNQANVAVAAQALGDASPVYQALFALPQGAVAPAFDQLSGEIYPSVSTVIQQESIYVRDAVGARLRQSVTGGDADALSAAAKATGQATAALSQDLTPTLWAQGYGAWGNAFGNGNAATIASSVGGFLAGLDVAVAPNVRAGIVGGFSQTKVDVNARSSTGTIDNYTVGLYLGGQFGALGLRGGASYSWHDIQADRSVLFSGFSSAQSSGYSLGTTQLFGEAGYRMAFGAYELEPFAGLAYVNLSSGSATETGYGSAGLGVNVQGMSTLYSTLGVRAATSFLLGGRALTPSATLGWQHAFGDTTPTAATRFLGGATPFQVQGVPIAEDTMLVGAGLAYALSDLATIQVNYSGQLATTASQNAVSAQFSLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBP7</accession>
    <name>A8IBP7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isochorismatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="267" mass="26843" checksum="0DE4A50672BE418D" modified="2007-12-04" version="1">MRDAMGDLDAIAGRHVLVTGAGSGIGASVARRLGRAGARVTLAGRREAPLRAVAADLPDGAAHVVAGFDVTDPQAIADGLAGARAAFGPVSILVNNAGAAETAPFGRTSLAQWQSVIAVDLTSVFLVTQAVLPDLEAGGAGGRIVNIASTAGLVGYRYVSAYCAAKHGVIGLTRSLALELARTGITVNAICPGYTDTPLVREAIAAIIAKTGRTEAEVLAEMTAGNPQRRLVDPDEMAETVAWVVSPGAASINGQAIAVAGGEVMVG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000259" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <sequence length="351" mass="38495" checksum="270941F0E9505A29" modified="2007-12-04" version="1">MLEYRRLGRTDLKVSSIMLGTMTWGQQNTEAEGHAQLDLALDAGINFIDTAELYSIPPMAETQGSTERIIGQWFKSRKNRDKVILASKVVGRSDSTYFRASGEGTKLDRANITEAVENSLKRLQTDYIDLYQLHWPDRAVPLFGNSAGTRARGGGDGTEVPVAETLGVLEDLVKAGKIRHIGLSNETAWGAHKFLLEAERGHGPRIVSVQNAYNLINRTYEVGLAEFAERDDVGLLAYSPLAQGFLTGKYRQGARPEGARMTLFNRGQRYEKPGTAEAIEDYAALAKELGLSLVQLSLAWVTSRPFVTANIIGATSIAQLKENLATVDVAITQEIEEKVNAIFQLRGSPAP</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="74" xmlns="http://uniprot.org/uniprot">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <sequence length="330" mass="35665" checksum="3DCA58778BFE0BCA" modified="2007-12-04" version="1">MTAQCTGATSDRIVKGVRMASMFLMSLLASDWENQRAFLAVLRTGSLSAAARELGLAQPTVRRRIEALEQALGTPLFTRSPAGLLPTEAARTLGPHAEAMAAAAAAFQRAASGPRAEISGTVRITASDMIGTQVLPGLIEPLMARHPRLTLEVHLSNRTQDLLRQEADIAVRMVRPTQSALVIRAIGIVRLGLFATPAFVERHGMPERLSDLSRYPLIGPDRDAADLRATEQLLGPDVPGALTYRTDNHPAQFAAVRAGLGIGVCQVNLAARPPALIPILPEAFEMRLDTYLVMHEDLKRVRRVRVVFDHLARTLGAYCHGTTEPTSGVL</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3" key="2">
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="181" mass="20280" checksum="13E072FB15642B3F" modified="2007-12-04" version="1">METDTAIVIRPTRDEDVDAMLAIYRHHIRRGVEEGVDDGSPEPDDLKDRRKNLKNRRLPHIAALFNGEVVGYAYVVPFRKRPAYRYAVKHSIYVHHDHTGRGIGRDLMQGLVDACAAAGFRQMIGYIDADNSASLTLHERFGFTRVGILPGVAYRFGRWADTVMVQRAIGLGATTPPPPSR</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="Pfam" id="PF10276"/>
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    <sequence length="82" mass="8789" checksum="7B8243CE893460F7" modified="2007-12-04" version="1">MADTGIPHFCNDLGVSVIEVGAREFMCIGAKPPFDHPHIFIDLGSDTEAVCSYCSTLYRYNPALKAGTAKPEGCVWADKPAA</sequence>
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    <accession>A8IF17</accession>
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            <fullName evidence="1">Ethanolamine ammonia-lyase large subunit</fullName>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <text evidence="1">Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.</text>
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            <text>ethanolamine = acetaldehyde + NH4(+)</text>
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            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
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        <text evidence="1">Binds between the large and small subunits.</text>
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    <comment type="pathway">
        <text evidence="1">Amine and polyamine degradation; ethanolamine degradation.</text>
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    <comment type="subunit">
        <text evidence="1">The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.</text>
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                <person name="Lee KB."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172124.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3601"/>
    <dbReference type="EnsemblBacteria" id="BAF89599">
        <property type="protein sequence ID" value="BAF89599"/>
        <property type="gene ID" value="AZC_3601"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3601"/>
    <dbReference type="eggNOG" id="COG3023">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079366_1_0_5"/>
    <dbReference type="OMA" id="HIGYHFV"/>
    <dbReference type="OrthoDB" id="1584918at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06583">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036505">
        <property type="entry name" value="Amidase/PGRP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002502">
        <property type="entry name" value="Amidase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015510">
        <property type="entry name" value="PGRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006619">
        <property type="entry name" value="PGRP_domain_met/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11022">
        <property type="entry name" value="PTHR11022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01510">
        <property type="entry name" value="Amidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00644">
        <property type="entry name" value="Ami_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00701">
        <property type="entry name" value="PGRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55846">
        <property type="entry name" value="SSF55846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetylmuramoyl-L-alanine amidase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PGRP" evidence="3">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="161" mass="17875" checksum="940855A6F0F5372D" modified="2007-12-04" version="1">MRKITHIVIHCAATPEGREVSVKEIDRWHRERGFAKIGYHYVIHLDGSIDPGRSEEEIGAHVQGHNATSIGICYIGGTEAHDVKKPKDTRTPAQKAAMERLVKELLTRYPGAEVLGHNDFPGVNKACPAFDTRKWWAEVSKRDAAPAPQPAFCKTCGQKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFK1</accession>
    <name>A8IFK1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="6" type="ordered locus">AZC_3624</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172147.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3624"/>
    <dbReference type="EnsemblBacteria" id="BAF89622">
        <property type="protein sequence ID" value="BAF89622"/>
        <property type="gene ID" value="AZC_3624"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3624"/>
    <dbReference type="eggNOG" id="COG1186">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036856_6_0_5"/>
    <dbReference type="OMA" id="YVFHPYQ"/>
    <dbReference type="OrthoDB" id="928964at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="5">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="376" mass="41591" checksum="810CF8382B20C989" modified="2007-12-04" version="1">MRAELAAKVDEINASVDLLRQHLNVDRSRRRLAELNAIAEDPTLWDDPERAQKIMQERTSLEDALNAIDRITRDLTDNIELIELGEAEGDESVITEAAGALDALKAELARRELDALLSGEADSNDTYLEVHAGAGGTDSQDWAEMLLRMYRRWCERHGFKVELVDESAGEQAGLKSATIIVKGHNAYGWLKTEAGVHRLVRISPFDSNARRQTSFASIDVYPVIDDRIVVEINESDVRVDTMRSGGAGGQHVNKTESAVRLTHIPTGIAVVSQGDRSQHKNRATAWNMLRAKLFEMELKKREEAAAAEQAARTDIGWGHQIRSYVLQPYQLVKDLRTGVTSGTPQEVLDGDLDPFMEAALAQRAYGGGPGQVEDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFZ4</accession>
    <name>A8IFZ4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Ferric uptake regulation protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fur</name>
        <name evidence="6" type="ordered locus">AZC_0006</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the Fur family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0006"/>
    <dbReference type="EnsemblBacteria" id="BAF86004">
        <property type="protein sequence ID" value="BAF86004"/>
        <property type="gene ID" value="AZC_0006"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0006"/>
    <dbReference type="eggNOG" id="COG0735">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_096072_3_2_5"/>
    <dbReference type="OMA" id="MKHFAIF"/>
    <dbReference type="OrthoDB" id="1630127at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="142" mass="16318" checksum="4D13E8A69C9634C9" modified="2007-12-04" version="1">MSEKISAIEEACLAKGMRMTDQRRVIARVLSQSADHPDVEELYGRASAIDANISISTVYRTVKMFEDAGIIARHEFGDGRSRYEPVPDEHHDHLIDLRSGRVLEFRSEEIERLQEEIARRLGYRIVGHRLELYVVPLDEEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG46</accession>
    <name>A8IG46_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0037</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0037"/>
    <dbReference type="EnsemblBacteria" id="BAF86035">
        <property type="protein sequence ID" value="BAF86035"/>
        <property type="gene ID" value="AZC_0037"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0037"/>
    <dbReference type="eggNOG" id="COG0156">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015846_11_3_5"/>
    <dbReference type="OMA" id="PFFRVHE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="88"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="454" mass="48606" checksum="0B4FC4A8B71A0034" modified="2007-12-04" version="1">MTKKADAGRLSDTERSAFLSSMRRTAAPQPARTAAVAAPVRDVSFETLPGFKMLKTQRAAADLLGLSNPFYQTHATRAGAQSIIGNRPVINFASYDYLGLNGHPEITAAVAEAAAEWGTSVSASRLTAGERPFHQQFEAELAALYETEDALVFVGGHATNVSTIAALLTPKDLVIHDALAHNSIVVGAELSKANRRIFPHNDLDALETILETARDKHERCLIVTEGLFSMDGDGPDLARLVDIKTRWGAWLMMDEAHSLGVLGATGRGIFEHQGVDPRGVDIWMGTLSKTLVGCGGYIAGSSDLITYLKFQAPGMVYSVGLPATTSIGSMTALRIMRREPERVARLQANGQRFLEKARAAGLDTGDSWGYAVSPVVLGDSLRTVMLAGRLLERGINAFPIIPPGVPEKSARLRFFISASHTAEDIDTAVAAVTEEIARLDAEGVSVAKVADLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG48</accession>
    <name>A8IG48_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0038</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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    <sequence length="254" mass="26134" checksum="AF8DFE0924857ECE" modified="2007-12-04" version="1">MAAELTVITGASSGIGAALARALAKPGAALALVGRNAERLESVAQDCRARGALCVTGALDVCDRPALEAFLDGLGEPVGLFIANAGILDGRRDGETVESGAAAHRVLDTNLLATVDALHMVLPGMRARRKGRLLLIASLAAFAPLPDAPAYSAAKAGLLSYGLALREALHGEGISVCVACPGYVTSAMSAQHLGHRPGEITADDAAARILGALERDAAVSGFPFTLYWSSRLSLLVPAFVRRLGMKGLRFRVGG</sequence>
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                <person name="Aono T."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="334" mass="38117" checksum="BF558B692F90AED9" modified="2007-12-04" version="1">MRGNSLFKRTYNQCLSLLGDLPPGARLGSEAQLAQVLEVSRTTVRAVLAALAEAGLVTAEAGRRQLARHPTPAHYFPEPQTESVRASVERQFMQWVLQGDFRPGQLIHCAELARQFNTSTTAIREYLSHFSHFGLIERRPNSAWVFKGITADFAAEIYEIREMFELRSAQRFASLPPEAPAWRELDALEAEHHALLKEIHVRYRDFSRLDERLHRLIHDASHNRFMMDFYDVISMIFHYHYQWNKADEKERNTVAIHEHLAYIAALRSRDARAIEAKCRAHLRTARSTLLRSIDAGPLRPGASLPLDPDRPPLALPVGPSHSKAKRSPVAARRR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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        <location>
            <begin position="15"/>
            <end position="437"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
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    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="89" mass="9576" checksum="D5F13C0B04584DD3" modified="2007-12-04" version="1">MALAENDLAEIEKILSAPDNGSGVIATLRGLLPHLSWTGCDASDMSDEPFRTYPAYEVHLLDTADHCVQLTSDPARATGVVLAKRKVKP</sequence>
</entry>
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        <submittedName>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171959.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3436"/>
    <dbReference type="EnsemblBacteria" id="BAF89434">
        <property type="protein sequence ID" value="BAF89434"/>
        <property type="gene ID" value="AZC_3436"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3436"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114962_1_0_5"/>
    <dbReference type="OMA" id="CLYKIHT"/>
    <dbReference type="OrthoDB" id="1755405at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="159" mass="17719" checksum="25A370B3E915DF47" modified="2007-12-04" version="1">MIEMFPEAELINFGDVPVAINALLQQGVAAYRHDHAKADALFRRALAEAPGELPVYFCLYKIHTYQGHLSEAEAAAQSGLREAARQAGWDEDWRAWQPRDEAPDGPGRFALYTLKALAFIHLRQNRVEEAERKLAALRQLDPAGVVGWRVIEALAEGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIV3</accession>
    <name>A8IIV3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfur carrier protein FdhD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">fdhD</name>
        <name evidence="4" type="ordered locus">AZC_3455</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FdhD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_3455"/>
    <dbReference type="EnsemblBacteria" id="BAF89453">
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        <property type="gene ID" value="AZC_3455"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3455"/>
    <dbReference type="eggNOG" id="COG1526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056887_2_1_5"/>
    <dbReference type="OMA" id="RYCAGAT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:sulfur carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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    <dbReference type="HAMAP" id="MF_00187">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003786">
        <property type="entry name" value="FdhD"/>
    </dbReference>
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        <property type="entry name" value="PTHR30592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02634">
        <property type="entry name" value="FdhD-NarQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015626">
        <property type="entry name" value="FdhD"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF53927"/>
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        <property type="entry name" value="fdhD_narQ"/>
        <property type="match status" value="1"/>
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    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="3">
        <location>
            <position position="126"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89453.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <sequence length="293" mass="30738" checksum="5A7F673F4CDAC675" modified="2007-12-04" version="1">MTKAPSLSPDDLPEIPDIPEPVRQVARAVWREGEVAQGERTVPEETPVALTYNGTTHAVMMASPIDIEAFALGFSLTEGIIRSSADILSLDVIAVEDGIEARMWIAEERMALLGARRRYLAGPTGCGLCGVESLAEAVKPAAQVAGDLVIEASALLEAMAALGPAQTLNHETRAVHAAGFYQPGTGLLAVAEDVGRHNALDKLVGKVARLPEANPASGVLLLTSRVSIEMVQKAAVLGVPVIAAVSAPTSLAIRTAERAGITLAAIVRSDGFELFTHPRRISLGTNQRQAHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ87</accession>
    <name>A8IJ87_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168797.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0266"/>
    <dbReference type="EnsemblBacteria" id="BAF86264">
        <property type="protein sequence ID" value="BAF86264"/>
        <property type="gene ID" value="AZC_0266"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0266"/>
    <dbReference type="eggNOG" id="COG1522">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091233_0_0_5"/>
    <dbReference type="OMA" id="CLECHVV"/>
    <dbReference type="OrthoDB" id="1844486at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="154" mass="17420" checksum="50368D38FA3F7BE2" modified="2007-12-04" version="1">MDETLDRIDLKILRLLQANGRMSNADLAEAVAVSPATCHRRTQRLFEQGYLSGVRAQVNPHKVERGTLVMVGVVLDRSTPESFGEFERAVAKLKFVLDCHLVAGDFDYFLKIRVGDMADFNRIHAQQLIALPSVRQTRTFFVMKEVVDNAPLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJJ6</accession>
    <name>A8IJJ6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0316</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0316"/>
    <dbReference type="EnsemblBacteria" id="BAF86314">
        <property type="protein sequence ID" value="BAF86314"/>
        <property type="gene ID" value="AZC_0316"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0316"/>
    <dbReference type="HOGENOM" id="CLU_2010564_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="123" mass="13961" checksum="3643C74345E971AE" modified="2007-12-04" version="1">MGRDLGRWMGTARVGWVVMLALLVAACSSGPGEADMKEAMDRLFRQEVDTYNAKVKEENKRLGRAKFAEKSYPVIAQLKKIDCVRPDSKPGYICYFEMSLDGMQQKRPGRFYVEGGSWVYARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJL9</accession>
    <name>A8IJL9_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">Quaternary ammonium compound-resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0326</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168857.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86324">
        <property type="protein sequence ID" value="BAF86324"/>
        <property type="gene ID" value="AZC_0326"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0326"/>
    <dbReference type="eggNOG" id="COG2076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_133067_0_2_5"/>
    <dbReference type="OMA" id="ATTAMKY"/>
    <dbReference type="OrthoDB" id="1921902at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042221">
        <property type="term" value="P:response to chemical"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="109" mass="11042" checksum="C8D2975A6DDF303F" modified="2007-12-04" version="1">MTYALLFVAIVAEVIATSALKAAEGFTRLVPSLIVIVGYGVAFVCLSLTLKTIPVGIAYATWSGVGIVLVAGVGWALYGQSLDLAGAVGLGLIIAGVLIVNLVSKTAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJN5</accession>
    <name>A8IJN5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ornithine decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0333</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168864.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0333"/>
    <dbReference type="EnsemblBacteria" id="BAF86331">
        <property type="protein sequence ID" value="BAF86331"/>
        <property type="gene ID" value="AZC_0333"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0333"/>
    <dbReference type="eggNOG" id="COG0019">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026444_1_3_5"/>
    <dbReference type="OMA" id="SFFVCDL"/>
    <dbReference type="OrthoDB" id="861683at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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        <property type="entry name" value="Peptidase_S24"/>
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        <property type="entry name" value="SSF51306"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S24" evidence="1">
        <location>
            <begin position="99"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="222" mass="24071" checksum="F00AAE6573E969F5" modified="2007-12-04" version="1">MLTHGQIWTAIDRLAEANGLSASGLAKRAGLDSTAFNRSKRITSDGRPRWPSTESVSKILSATNTSMRAFLALLEGEDIGPSGFSEEPAPPFRPQRAIPHIGLAQAGDGGFFDDAGFPVGSGWDEILFPEVEDEHAYALEISGDSMLPLYRPGDLVVVSPAASVRKGDRVVVKTRDGEVLAKELVRRTARTVELRSLNPEYEGRTLAATDVLWIARIIWASQ</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3880"/>
    <dbReference type="EnsemblBacteria" id="BAF89878">
        <property type="protein sequence ID" value="BAF89878"/>
        <property type="gene ID" value="AZC_3880"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3880"/>
    <dbReference type="eggNOG" id="ENOG5032Z6E">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2986617_0_0_5"/>
    <dbReference type="OMA" id="ARARWMA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="57" mass="6355" checksum="54FC09672BF3D216" modified="2007-12-04" version="1">MDAVADGADWKEVVAVLFGVDAAHEPERARNIFDSHLARARWVAASGYKDLLRTRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILV6</accession>
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        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
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        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ordered locus">AZC_0425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
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        <property type="protein sequence ID" value="BAF86423.1"/>
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    <dbReference type="GO" id="GO:0005737">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Chaperonin_GroES"/>
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        <property type="entry name" value="Chaperonin_GroES_sf"/>
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        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
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    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
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    <dbReference type="PANTHER" id="PTHR10772">
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CHAPERONIN10"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000259" key="1">
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMK9</accession>
    <name>A8IMK9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">luxR</name>
        <name evidence="5" type="ordered locus">AZC_0572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169103.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0572"/>
    <dbReference type="EnsemblBacteria" id="BAF86570">
        <property type="protein sequence ID" value="BAF86570"/>
        <property type="gene ID" value="AZC_0572"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0572"/>
    <dbReference type="eggNOG" id="COG2197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_90_8_5"/>
    <dbReference type="OMA" id="DVWVPPD"/>
    <dbReference type="OrthoDB" id="1687028at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="149"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="223" mass="23493" checksum="049F5A3F8F204BDF" modified="2007-12-04" version="1">MGDADAGYRLVIADDHPLFRGALREAVAGEFPSAEIVEVGTFDDLHALLEREDDFDLILLDLTMPGARGFSGLIYLRAQYAGVPVVVVSGNEEPAVIRRCIDLGASGFIPKTMGIAGMRQSVATVLAGGTSVPPDLGPPTAQDGEADAIISRLATLTPQQVRVLMMLAEGRLNKQIAYELGVSEATVKAHVSAILQKLGVESRTQAVIAVSKVDAGLWSANQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IML9</accession>
    <name>A8IML9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-hydroxyisobutyrate dehydrogenase</fullName>
            <shortName evidence="5">HIBADH</shortName>
            <ecNumber evidence="5">1.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0577</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:17681"/>
            <dbReference type="ChEBI" id="CHEBI:11805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57700"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid degradation; L-valine degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the HIBADH-related family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.31" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169108.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0577"/>
    <dbReference type="EnsemblBacteria" id="BAF86575">
        <property type="protein sequence ID" value="BAF86575"/>
        <property type="gene ID" value="AZC_0577"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0577"/>
    <dbReference type="eggNOG" id="COG2084">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035117_6_0_5"/>
    <dbReference type="OMA" id="WSSEVNN"/>
    <dbReference type="OrthoDB" id="1245550at2"/>
    <dbReference type="UniPathway" id="UPA00362"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008442">
        <property type="term" value="F:3-hydroxyisobutyrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006574">
        <property type="term" value="P:valine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011548">
        <property type="entry name" value="HIBADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015815">
        <property type="entry name" value="HIBADH-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="NADP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000103">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01692">
        <property type="entry name" value="HIBADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0101">Branched-chain amino acid catabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_2" evidence="6">
        <location>
            <begin position="4"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_binding_11" evidence="7">
        <location>
            <begin position="165"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000103-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU910714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="297" mass="29527" checksum="097D7BF3063483F1" modified="2007-12-04" version="1">MAVIAFIGLGNMGGPMAANLVKAGHAVHGFDLSEAAKAAAAARGVSLAVSAAEAVKAADVVVTMLPSGPHVLGAVTGADGLFAAARPGTLFIDSSTIDVESARAFHAGAEAAGMASLDAPVSGGVGGAEAGTLTFMAGGSEAAFSAAKPHLERMGKKIVHCGGAGAGQAAKICNNMILGISMIAVSEAFVLGEKLGLSHQALFDVASTSSGQCWSLTTYCPVPGPVPTSPANREYQPGFAAALMLKDLKLSQQAADQAGAATRLGAEAAALYSAFEAEGNAGRDFSGIIEWIRARTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMN7</accession>
    <name>A8IMN7_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Cytochrome d oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0585</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169116.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0585"/>
    <dbReference type="EnsemblBacteria" id="BAF86583">
        <property type="protein sequence ID" value="BAF86583"/>
        <property type="gene ID" value="AZC_0585"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0585"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_0_0_5"/>
    <dbReference type="OMA" id="FLWGVAF"/>
    <dbReference type="OrthoDB" id="761975at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="384" mass="41554" checksum="FD1D5CC73D81F88A" modified="2007-12-04" version="1">MILHDLINYEVLRLIWWLLLGVLLIGFAVTDGFDLGVATLLPFVGRTDVERRVAINTIGPVWEGNQVWLILGGGAIFAAWPPLYAVSFSGFYLAMFAILAALILRPVGFKYRSKRDSEAWRKGWDWALFVGGFVPALIFGVAVGNTLQGVPFRLDDDLRIFYDGSFFGLLNPFALLCGLLSVAMLVTHGATWLQLKADGPVADRARTYGSISALVAVVLFVLAGVLLYSFVAGYKITSPINPLGPSNPLLKTAATAPGAWFANYATAPGLLAAPAIGIVGLLAAGLALRLKWEGAGVLLSGLGIFGIISTVGVSMFPFILPSTVDPRFSLTVWDASSSHLTLFIMLVSTVIFLPIILLYTTWVYRVMWGKVDAKAIREDRGHAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMS3</accession>
    <name>A8IMS3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrogen uptake protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hupD</name>
        <name evidence="4" type="ordered locus">AZC_0601</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A31 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169132.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0601"/>
    <dbReference type="MEROPS" id="A31.002"/>
    <dbReference type="EnsemblBacteria" id="BAF86599">
        <property type="protein sequence ID" value="BAF86599"/>
        <property type="gene ID" value="AZC_0601"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0601"/>
    <dbReference type="eggNOG" id="COG0680">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_099037_0_1_5"/>
    <dbReference type="OMA" id="MGAKKMS"/>
    <dbReference type="OrthoDB" id="1858718at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004419">
        <property type="entry name" value="Pept_A31_hyd_express"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023430">
        <property type="entry name" value="Pept_HybD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000671">
        <property type="entry name" value="Peptidase_A31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30302">
        <property type="entry name" value="PTHR30302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01750">
        <property type="entry name" value="HycI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00446">
        <property type="entry name" value="HYDRGNUPTAKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53163">
        <property type="entry name" value="SSF53163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00140">
        <property type="entry name" value="hupD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00072">
        <property type="entry name" value="hydrog_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0533">Nickel</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="208" mass="22061" checksum="75CC7B4B280B3724" modified="2007-12-04" version="1">MDGEHILVLGIGNILWADEGFGVRVVEALDRAFTFPDHVTLLDGGTQGLYLLPALEEADVVVILDAVDYGLPPGTLHCLSDGDVPAVLGARKLSLHQTGFQEVLALLQLRGCLPRHLRLVGVQPHTLDDYGGGLTPPVAAQVAPAVTEVLRLLTEEFDVPVRPRDSESSEGLVTAAVARAAYEAGRPSAQDACRIGDARVLARTFGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMW3</accession>
    <name>A8IMW3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3669</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3669"/>
    <dbReference type="EnsemblBacteria" id="BAF89667">
        <property type="protein sequence ID" value="BAF89667"/>
        <property type="gene ID" value="AZC_3669"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3669"/>
    <dbReference type="eggNOG" id="COG0705">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055068_5_0_5"/>
    <dbReference type="OMA" id="ACRFAFP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="129"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="306" mass="32789" checksum="F527715F89F07B0D" modified="2007-12-04" version="1">MPQTASVRALNPFLTLTRFPLDDTAVRAPDHRWPGRTLPVFWVALLPARAYVRRVLDITRSPGAMPRQPVFNVPGVVTALAAAMAVIHLVRTYVLSEGADLEILALFSFVPGRYDAEAALALPGGIGADIWTFVTYALLHANWIHLGVNLIWMLAFATPVARRFGPARFLAFFAVTAAVGAFAHLITHRDAMVPMIGASAAIAGLMAAAVRFAFAPGGSLSGRRGPLPDHMPAQGLGEAFRDPRVLGFMGVWIAANLLFGVGVTMPGAEDGEVAWQAHLGGFFAGLLLFSFFDPVGRRLPREKTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8INC4</accession>
    <name>A8INC4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfate transport system permease protein CysT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cysT</name>
        <name evidence="12" type="ordered locus">AZC_3733</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell inner membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172256.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3733"/>
    <dbReference type="EnsemblBacteria" id="BAF89731">
        <property type="protein sequence ID" value="BAF89731"/>
        <property type="gene ID" value="AZC_3733"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3733"/>
    <dbReference type="eggNOG" id="COG0555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_14_0_5"/>
    <dbReference type="OMA" id="VFISGNM"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011865">
        <property type="entry name" value="CysT_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005667">
        <property type="entry name" value="Sulph_transpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406">
        <property type="entry name" value="PTHR30406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406:SF10">
        <property type="entry name" value="PTHR30406:SF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00969">
        <property type="entry name" value="3a0106s02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02139">
        <property type="entry name" value="permease_CysT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="55"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF89731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="273" mass="29168" checksum="9CE4836A0EA9AE2A" modified="2007-12-04" version="1">MSSVIPGFRLSFGITLTYLCLIVLLPVAALLLQAADVGLARYIAIMTSPRTLASFQVTFTTAAIATAFNAIYGLALAWVLVRYEFPGKRLLDALVDVPFALPTAVAGLALTAIFAKNGWYGAQLAQWGIQVAYAPAGIACAMAFTSIPFVVRTVQPVLEDLAGDVEEAATTLGASDFRVFRTVILPALFPAFLAGCSLAFARSLGEFGAVVFIAGNQPFRTEIVALLAFIRLEEYDYPAAAAIAATMLGLAFLLLLTVNAIQAWHQRRAIRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8INX0</accession>
    <name>A8INX0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative insertion sequence transposase protein</fullName>
        </submittedName>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3801</name>
        <name evidence="3" type="ordered locus">AZC_3845</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="2">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="2">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="STRING" id="438753.AZC_3801"/>
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        <property type="entry name" value="Trp_repressor/repl_initiator"/>
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        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="310" mass="35438" checksum="A71192ECAA9144FF" modified="2007-12-04" version="1">MNNPHQNARTTPLGRAEMVRRIVEEGRPVAEVAAGFGISERTARKWLARWRAEGTSGLQNRSSRPHAADDEAGRFWRAMAARLRREYRLSGEEIAVRLGFARSTVAGWLTRMRLGSLAALMPQEPVRRYQRERPGELIHLDIKKLARFAGVGHRITGNRRGASEGMGYDFLHVAIDDATRLAYVEVLPDERRGSTTGFLIRALRWFRARGIRVERVMTDNGAGYIARLFRKVLRILGIRHIRTRPYTPKTNGKAERFIQTLLREWAYAIPFPSSERRAADLPRWLAWYNHQRPHGSLDRRTPAQALAGTT</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VirD4/TraG family.</text>
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    </dbReference>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
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        <location>
            <begin position="75"/>
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        <location>
            <begin position="571"/>
            <end position="631"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="586"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="663" mass="73678" checksum="27B0E024AB13D458" modified="2007-12-04" version="1">MSATKILWGQILTVPLIVLAAIWGATQYVAWSLGYQAQLGAPWFALVGLPIYYPPAFFWWWYFFDAYAPGVFFRGALIAASGGFLSIAVAIALSVWRAREASRVETYGSARWAEREEVRAAGLLGTDGVVLGRYERDYLRHDGPEHVLCFAPTRSGKGVGLVVPSLLTWPGSAIVHDIKGENWQLTAGFRARHGRVLLFDPTNARSAAYNPLLEVRRGEWEVRDVQNIADILVDPEGSLEKRNHWEKTSHALLVGAILHVLYAEKDKTLAGVAAFLSDPKRPIETTLDAMMKTAHQGEAGPHPVIASAARELLNKSDNERSGVLSTAMSFLGLYRDPVIAEVTRRCDWRIADIIGGKRPSTLYLVVPPSDINRTKPLIRLLLNQIGRRLTEDLQAKAGRHRLLLMLDEFPALGRLDFFESALAFMAGYGLKAFLIAQSLNQIEKAYGPNNSILDNCHVRVSFATNDERTAKRVSDALGTATEMKAMKNYAGHRLSPWLGHLMVSRSETARPLLTPGEVMQLPPTDEIVLVAGTPPIRAKKVRYYEDARLRDRLLPPPMPSRGLTVQHDDWTALPLPRPHNGAGRGAAVEGRDDDPTGSEHRHQPELSRVKPVERSAPIENEFEFDLDRDDEMDDVPARNRRMKGLMQGVARQVSLNPNDGMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="35" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Akiba N."/>
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                <person name="Suzuki S."/>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169281.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0750"/>
    <dbReference type="EnsemblBacteria" id="BAF86748">
        <property type="protein sequence ID" value="BAF86748"/>
        <property type="gene ID" value="AZC_0750"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0750"/>
    <dbReference type="eggNOG" id="ENOG50339RG">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_136035_0_0_5"/>
    <dbReference type="OMA" id="RGWFYFA"/>
    <dbReference type="OrthoDB" id="2078642at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="166" mass="17576" checksum="5EDB831914BC6E8E" modified="2007-12-04" version="1">MDSVFRLLLRILVIPIGLLAAILAGVAVILFGQWRIGALANQSLGLAPETWVAIMEALFTGTFLVTFLVSVMWLVALVGVLFAEVFAARSWLFHVANGAVSAFVGARLFPRISGEATAPADPFYILAAGLAGGLVYWLVAGWSAGFWKPVRSRPPSPTPQPPASAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-10-01" modified="2022-08-03" version="104" xmlns="http://uniprot.org/uniprot">
    <accession>Q07740</accession>
    <accession>A8IP10</accession>
    <name>NODB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Chitooligosaccharide deacetylase</fullName>
            <ecNumber>3.5.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">nodB</name>
        <name type="ordered locus">AZC_3817</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1989" name="Mol. Gen. Genet." volume="219" first="289" last="298">
            <title>Common nodABC genes in Nod locus 1 of Azorhizobium caulinodans: nucleotide sequence and plant-inducible expression.</title>
            <authorList>
                <person name="Goethals K."/>
                <person name="Gao M."/>
                <person name="Tomekpe K."/>
                <person name="van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
            <dbReference type="PubMed" id="2615763"/>
            <dbReference type="DOI" id="10.1007/BF00261190"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text>Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location>Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.-"/>
    <dbReference type="EMBL" id="L18897">
        <property type="protein sequence ID" value="AAB51163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JQ0394">
        <property type="entry name" value="JQ0394"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172340.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q07740"/>
    <dbReference type="SMR" id="Q07740"/>
    <dbReference type="STRING" id="438753.AZC_3817"/>
    <dbReference type="EnsemblBacteria" id="BAF89815">
        <property type="protein sequence ID" value="BAF89815"/>
        <property type="gene ID" value="AZC_3817"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3817"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021264_0_0_5"/>
    <dbReference type="OMA" id="NHAMRDE"/>
    <dbReference type="OrthoDB" id="1701876at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026402">
        <property type="entry name" value="Nodulat_NodB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04243">
        <property type="entry name" value="nodulat_NodB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0536">Nodulation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000172746" description="Chitooligosaccharide deacetylase">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="15"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="site" description="Raises pKa of active site His" evidence="1">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; AAB51163." evidence="3" ref="1">
        <original>AT</original>
        <variation>TA</variation>
        <location>
            <begin position="44"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; AAB51163." evidence="3" ref="1">
        <original>A</original>
        <variation>T</variation>
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; AAB51163." evidence="3" ref="1">
        <original>S</original>
        <variation>P</variation>
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="sequence conflict" description="In Ref. 1; AAB51163." evidence="3" ref="1">
        <original>G</original>
        <variation>S</variation>
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="3"/>
    <sequence length="210" mass="23348" checksum="2915069D19E46091" modified="2008-02-26" version="2">MSVLGQAARITQNQSSIYITFDDGPHPSVTPAVCEILREHSALATFFQIGRFAKEYPSISRQCQLDGHAIGNHTFDHPNLQDRAGEEVEYQISSAQKCLEHICGRGFVRHFRAPYGAWSTQILNVVNKIGLRPVSWSVDPRDWEAPRIENLINEILDNARPGSIILLHDGCPPDEAAMWDVRGGRAQTLAALRYVVPALQARGFALQPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQ98</accession>
    <name>A8HQ98_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dihydrofolate synthase/folylpolyglutamate synthase</fullName>
            <ecNumber evidence="6">6.3.2.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">Folylpolyglutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ordered locus">AZC_1025</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = (6R)-5,10-methylenetetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51912"/>
            <dbReference type="Rhea" id="RHEA-COMP:13257"/>
            <dbReference type="Rhea" id="RHEA-COMP:13258"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:136572"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>10-formyltetrahydrofolyl-(gamma-L-Glu)(n) + ATP + L-glutamate = 10-formyltetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:51904"/>
            <dbReference type="Rhea" id="RHEA-COMP:13088"/>
            <dbReference type="Rhea" id="RHEA-COMP:14300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:134413"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>7,8-dihydropteroate + ATP + L-glutamate = 7,8-dihydrofolate + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17839"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.12" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1025"/>
    <dbReference type="EnsemblBacteria" id="BAF87023">
        <property type="protein sequence ID" value="BAF87023"/>
        <property type="gene ID" value="AZC_1025"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1025"/>
    <dbReference type="eggNOG" id="COG0285">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015869_1_1_5"/>
    <dbReference type="OMA" id="YFEMGTL"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="12" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="18" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="19">
        <location>
            <begin position="46"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00000809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00030048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="BAF87023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="435" mass="45817" checksum="85C85B7DEEBDBC5A" modified="2007-12-04" version="1">MSPLGALLERLAALHPKKIDLSLERMERLAAALGNPERRLPPVVHVAGTNGKGSTVAYLRAALEAAGRRVHTYTSPHLVRFNERIRLAGELVDDARLCDALERVAAANDGGPITFFEVTTAAAFLLFAETPADVLLLEVGLGGRLDATNIIEAPVASVITPISIDHVEFLGDTLEAIAGEKAGIIKPRVPVIVGEQPDEALAVIERTAARRRAPLFARGQQWTVQEEAGRLVYSDEDGLLDLPRPRLMGPHQFDNAGLAVATLRAVPELRVPPPALEAGIRGADWPARLQRLPVGPLVARAPREAEVWLDGGHNAGGGQALAHALAELEERVPRPLVLVVGMLANKDVSGFLGAFAGLAREAICVPVPPEHNGTAPDDLARIAAGLGFSASTAGDVGAALDGLARYPLTPPPRVLVCGSLYLAGTVLAANETLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS30</accession>
    <name>A8HS30_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative amino acid ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_4132</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial solute-binding protein 3 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4132"/>
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        <property type="protein sequence ID" value="BAF90130"/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="479"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="546"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="235"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="622" mass="66870" checksum="A8ABFEF4905F24EE" modified="2007-12-04" version="1">MPNRPNPKREPAVRASDTAHDAHLLRQERETVHHDPVFRMRPPNLLWRRLLVLTLNVATVVAVGLWAGHLAGLAGWRVVDVALLCCVLLATPWIAIGFWNASIGLLLTHVLARGIEAAAPFLKGAAGQARLSSRTAILMTLRNEDPARAVLRLRAVKADLDATPFGGQFDYFLLSDTSRPEVAAAEEAEVARWQESDGVHRIHYRRRTVNEGFKAGNVRDFCARWGSGYDYMLPLDADSVMGAQAILSLVRILDAHPRIGILQSLVVGMPSASAFARIFQFGMRHGMRCYTLGASWWTGDCGPFWGHNALIRIAPFYAHCHLPVLPGAPPLGGPILSHDQVEAVLMRRAGYEVRVVPVESESYEENPPTIAEFIARDLRWCLGNMQYLRLQGLPGLKPVSRFQLLWAVLMFASVPAVPLALVLLPFAAFGLSAEEAEAIGPGAGALYGSLLVLGQFPKLAGLLDVALRRGGLAAYGGGLRFFASAALEIAFSLLLGAISALATTRFLMGLAFGRAAVGWNGQVRDAHALSFSAAVRGLWGQTLFGLLVGAALALAAPVLLLWTLPLLAGCWLAVPFAVLTAAPSFGQKLAAAGLCAIPEEGALPAILARLEPAAETRLERAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-02-10" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT64</accession>
    <name>ATP6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">atpB</name>
        <name type="ordered locus">AZC_4260</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase A chain family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172780.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HT64"/>
    <dbReference type="SMR" id="A8HT64"/>
    <dbReference type="STRING" id="438753.AZC_4260"/>
    <dbReference type="EnsemblBacteria" id="BAF90258">
        <property type="protein sequence ID" value="BAF90258"/>
        <property type="gene ID" value="AZC_4260"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4260"/>
    <dbReference type="eggNOG" id="COG0356">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041018_0_2_5"/>
    <dbReference type="OMA" id="FFDQFMS"/>
    <dbReference type="OrthoDB" id="867266at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023011">
        <property type="entry name" value="ATP_synth_F0_asu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045083">
        <property type="entry name" value="ATP_synth_F0_asu_bact/mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11410">
        <property type="entry name" value="PTHR11410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00449">
        <property type="entry name" value="ATPASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0066">ATP synthesis</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0138">CF(0)</keyword>
    <keyword id="KW-0375">Hydrogen ion transport</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000362238" description="ATP synthase subunit a">
        <location>
            <begin position="1"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <sequence length="250" mass="27367" checksum="8CFE2592E2278770" modified="2007-12-04" version="1">MTVDPIHQFEIQRYVELLRVSGVTVSFTNSAAFMVGIVALIFFFLTYATRGRTLVPGRMQSVAEMGYEFIAKMVRESAGTEGMVFFPLVFSLFVFVFVANVIGLVPYTFTITAHIVVTAALALLVIGTVVIYGFYKHGTHFLHLFVPSGVPAFLLPFIVLIEVISFLSRPISLSLRLFANMLAGHIALKVFAFFVVGLGSAGFLGWLGATLPFFMIVALTALELLVAILQAYVFAVLTSIYLNDAVHPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTA9</accession>
    <name>A8HTA9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0816</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169347.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0816"/>
    <dbReference type="DNASU" id="5690471"/>
    <dbReference type="EnsemblBacteria" id="BAF86814">
        <property type="protein sequence ID" value="BAF86814"/>
        <property type="gene ID" value="AZC_0816"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0816"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_6_5"/>
    <dbReference type="OMA" id="PNMDEGV"/>
    <dbReference type="OrthoDB" id="847343at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723035" evidence="2">
        <location>
            <begin position="31"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="46"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86814.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="282" mass="30726" checksum="C4768D806F0E5F84" modified="2007-12-04" version="1">MISRRNLATLLGAGATAAAAMGGLITPAAAQSADESTFDRIRRTKKLRIGAVAGGAPYYNKDLATGQWKGFYIDISKALADELECQLEITETTWGNSVLDLQANKIDIFFGLNPTPKRALVVDFSVPVFSNAFTMLTRKDFAPKTWAELNDPNVKIAVDVGSSHDQVVSRLCPKAQIVRLKTADEATMALVSGRVDAQCIILMLALTVRKKNPNVGQLLVPTPVFSTTSNAGFRRENDKTWRDYVNTWIEYNKGLGFIRSAIVTNMELVGVTEADMPAGIQL</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <dbReference type="KEGG" id="azc:AZC_0837"/>
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        <property type="entry name" value="DUF5681"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <begin position="110"/>
            <end position="133"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="220"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="51"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
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            <dbReference type="Pfam" id="PF18932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="220" mass="24134" checksum="95B22183E25F83E8" modified="2007-12-04" version="1">MPDWKAIEAEYGSMSTRKLAERHGVTEGAIRKRKAKGWAEPGVFGHRPKKEKPAKAATRPRQKKEASKKVRTERAVRTENAHQNAYQYAPPAPDVVRAEPSAPKQRGIPFQPGKSGNPAGRPKGSRNKLGEAFIAALHDDFIENGPETIQRVREEKPDQYLKVVASILPKELKVTTEVDLSDDELDRRIRQLAAALELEIGGEGGAGEAAGREAAPGRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="48" xmlns="http://uniprot.org/uniprot">
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="entry name" value="SocA_Panacea"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4065" evidence="1">
        <location>
            <begin position="88"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13274"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="213" mass="23474" checksum="F92B57C1EEE32F85" modified="2007-12-04" version="1">MWGIPALGAADARIWTFDTLQTILRGPSVAIAAGGWCDSHATPIVECGTWHWHLFSGGGLKMHSSLTIANRFLDLANEEGDTLTPMQLLKLVYIAHGWMLGLYGVPLINDEVQAWKYGPVIPKLYHSISQFRSDPVRGPLRAHDPDPLVSVENALIQQVYEIYGNMTGIELSRLTHQPGSPWAQTYQDGVSNIVISNDLIEDHYRTLASGAEA</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <text evidence="9">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
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        <subcellularLocation>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
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    <organism evidence="2 3">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="3">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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    <reference evidence="2 3" key="4">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="2 3" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022460">
        <property type="entry name" value="Flavoprotein_PP4765"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03862">
        <property type="entry name" value="flavo_PP4765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720711" evidence="1">
        <location>
            <begin position="28"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="405" mass="42470" checksum="E972F8B99EA73251" modified="2007-12-04" version="1">MQSRVSKVAVIGAGPAGLMAASCLAQAGVSVELFDRMPSPARKFLMAGRGGLNLTHSEPLERFLARYGSAAGRLAPAIRAFPPDALRAFAEGLGEETFVGSSGRVFPKSFKASPMLRAWLRHLAAAGVTLSARHHWTGWDADGALTFETPEGPRAVRVDATVLALGGASWPRLGADGGWRAVLEGAGLQVALFAPANMGVLLNWSAHLVPRFAGTPLKRIALACGAEHVRGEAVITAQGLEGGAIYALSRQIREAVERQGQADLVMDLRPDLSLDVLAQRLAAAPARLSFSERLRKAAGLAPVQIALLREGMNARPAEAAALARRIKALPLTVMGVCGLERAISSAGGLAWDEVGPDYALKACPDVFVCGEMLDWEAPTGGYLLQACFSTAVAAAEGVKARLKSD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVC4</accession>
    <name>UBIG_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquinone biosynthesis O-methyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-polyprenyl-6-hydroxyphenol methylase</fullName>
            <ecNumber evidence="1">2.1.1.222</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">3-demethylubiquinone 3-O-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.64</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ubiG</name>
        <name type="ordered locus">AZC_4300</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:44380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10914"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84422"/>
            <dbReference type="EC" id="2.1.1.64"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:31411"/>
            <dbReference type="Rhea" id="RHEA-COMP:9550"/>
            <dbReference type="Rhea" id="RHEA-COMP:9551"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:62729"/>
            <dbReference type="ChEBI" id="CHEBI:62731"/>
            <dbReference type="EC" id="2.1.1.222"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily. UbiG/COQ3 family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.222" evidence="1"/>
    <dbReference type="EC" id="2.1.1.64" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HVC4"/>
    <dbReference type="SMR" id="A8HVC4"/>
    <dbReference type="STRING" id="438753.AZC_4300"/>
    <dbReference type="PRIDE" id="A8HVC4"/>
    <dbReference type="EnsemblBacteria" id="BAF90298">
        <property type="protein sequence ID" value="BAF90298"/>
        <property type="gene ID" value="AZC_4300"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4300"/>
    <dbReference type="eggNOG" id="COG2227">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042432_0_0_5"/>
    <dbReference type="OMA" id="RGTHDWE"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102208">
        <property type="term" value="F:2-polyprenyl-6-hydroxyphenol methylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008689">
        <property type="term" value="F:3-demethylubiquinone-9 3-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00472">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010233">
        <property type="entry name" value="UbiG_MeTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01983">
        <property type="entry name" value="UbiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="chain" id="PRO_1000072393" description="Ubiquinone biosynthesis O-methyltransferase">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00472"/>
        </source>
    </evidence>
    <sequence length="253" mass="27514" checksum="35213B13AADD48CF" modified="2007-12-04" version="1">MRMTANATIDPSEVARFDALGAQWWDPKGKMAPLHAINPVRLGFVRDVLVRHFGHDARSLRPLKGLRILDIGCGGGLLSEPLARMGADMVGVDPAPGNIVVAQSHADEAGVRVDYRQGTAEELADAGERFDVVLALEVVEHVADVGLFLRRAGEMVNPNGIMIVSTLNRTVKSFALAIVGAEYVLRWLPRGTHRWDKFITPAELEAEMGAAGFEMSELAGMVFDPLRGEWKIAADTDVNYFLVGKPAFHTSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVN3</accession>
    <name>A8HVN3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conserved hypothetical membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4336</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172856.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4336"/>
    <dbReference type="EnsemblBacteria" id="BAF90334">
        <property type="protein sequence ID" value="BAF90334"/>
        <property type="gene ID" value="AZC_4336"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4336"/>
    <dbReference type="eggNOG" id="COG3333">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022936_2_0_5"/>
    <dbReference type="OMA" id="AMEGNLM"/>
    <dbReference type="OrthoDB" id="735109at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002823">
        <property type="entry name" value="DUF112_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01970">
        <property type="entry name" value="TctA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    </evidence>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Wiley G.B."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Liu CT."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Liu C.T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="211"/>
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    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="213"/>
            <end position="266"/>
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    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="7">
        <location>
            <begin position="306"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
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            <begin position="458"/>
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            <begin position="314"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
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            <dbReference type="PROSITE" id="PS50111"/>
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        <source>
            <dbReference type="PROSITE" id="PS50192"/>
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            <dbReference type="PROSITE" id="PS50885"/>
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        <source>
            <dbReference type="EMBL" id="BAF87562.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="562" mass="59192" checksum="CEB14BCA77559418" modified="2007-12-04" version="1">MLEAVMLSGLKIRTKLLLGFGVVVALMLLNAIWLTVSSRQIEAAMRASDAAADTVITMKDAFLEVRQGRVMAWSYMATGEPSYLSGRDTAFRNFDDIYKRALALKPSAEAVRLMDDFRAAVVGFRDAAVKMNDLKKQGVAATAPEMVAVMKDVDAGARLYAETNGKAAGFLAQQNDLAAKQAYDQLSSSNTITLALVVVLVAVSAIIAFLLSRAIATPVRDISGVIGQLAQGSTDADVPHRGRGDEVGDMAQSVEVLREALHEAHLTREAQAAREEDERRVLARRQALAEDFVSRMQQLASGFASSSQEVADSARNLSSTAEETSRQAQHVAHAAEEAATNVQTVAASSEELAASVSEITQQVSHSADVADVAFREAESSNARIVDLTNAAAAIGDVLNLIKGIADQTNLLALNATIEAARAGEAGKGFAVVASEVKELAGQTAKATTEISTKINEIQQATNGTVSSMSEIVRVVTDIKSISSSIASAVEQQGAATGEIAENCQRAASGTQQVTENIEGVGRSAQVTGAASQQLLSLSQNLSGQAADLRTVVERFVQDLNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYA1</accession>
    <name>A8HYA1_AZOC5</name>
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        <submittedName>
            <fullName evidence="11">Putative D-alanyl-D-alanine carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_1592</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S11 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1592"/>
    <dbReference type="EnsemblBacteria" id="BAF87590">
        <property type="protein sequence ID" value="BAF87590"/>
        <property type="gene ID" value="AZC_1592"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1592"/>
    <dbReference type="eggNOG" id="COG1686">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3266">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027070_1_1_5"/>
    <dbReference type="OMA" id="PRYYRYF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018044">
        <property type="entry name" value="Peptidase_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001967">
        <property type="entry name" value="Peptidase_S11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00768">
        <property type="entry name" value="Peptidase_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00725">
        <property type="entry name" value="DADACBPTASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SPOR" evidence="10">
        <location>
            <begin position="546"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="522"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="6">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR618044-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="629" mass="66581" checksum="8D15C3E442895B43" modified="2007-12-04" version="1">MHCTIWHAMSGLRLGNRTFLGCIQSSFLRYGLAGSRDTSSLSFTAMHHQPGPPPRPGRWNSFMTLALGPSLTRKWLAAALVAALAVTATAAEAKPKKSRSAAQSSSSRSSGGDEYAGWKRGTAAIVVDGNTGKVLYEENADSLRHPASLTKIMTLYMLFEQLQAGRLKLDSDLPVSAHAASQSPTKLNLRPGSTIEVEDAIKAVVTRSANDAAVVIGEAIGGTESNFAEMMTRKARALGMSNTTFRNASGLPNPGQVTTARDLSVLGRAIQDRFPREYRYFSTRAFVYRGETIGNHNRLMLRMEGVDGIKTGYTNASGFNLVTSLHRDDRFLVGVVLGGSSASSRDQRMASILTSNLPRAYAGGRVAPKVIETAQRDDEPAPRPMPIPVAARQSEPAQAVAPLPPPQRVAYAAADPVTTASVAPVRAPTPGSAEPIKPVAVRTTTIARPGSNQMPAPTFSGQPSGTLGYLPAQSAAAAQSDMESPPGDLLMGPPPERETSPVAHGVRTASAAPVALPAATVASATTPAPKPVRVASTGPVATPRSAPPRSGWIIQIGAFGGEKEARSQLDAARGKAGKLLKSADPYTEKVEKGRSDIYRARFAGLTEKDAKEACRLLERNKFDCMTLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYV4</accession>
    <name>A8HYV4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4504</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173023.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4504"/>
    <dbReference type="EnsemblBacteria" id="BAF90502">
        <property type="protein sequence ID" value="BAF90502"/>
        <property type="gene ID" value="AZC_4504"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4504"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_688211_0_0_5"/>
    <dbReference type="OrthoDB" id="948440at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="400" mass="44377" checksum="55EFDA508292FB66" modified="2007-12-04" version="1">MRVLYFTIVPLMDDSNGGNMCCRNHVRRLSQDPDIELFVLWAGEPAHVAGTAAFLAEIGVPFETVAFEEGDAHPRDGSPAALAEYAEVRAYHHPWELRALNQHHVQEAADRMIAAQGIDCVVADYLQSALFVDLGRRDVRTALVTLNREDSFYRDLISLGLTPHPPEAAEISHRRLVAFERATYARVGKVIAIGPPDMPTGEVRSPPAYITPYFDPRPEPWRHSGTRNCLFVGNIGHYPNRLAANWLTRELAPRLHGIAPDIRITIVGATPDQIPPEDRHPNLECLGIADAATVEALMRTADLMLCPVENDYGVKFKAVQALSYGIPLLASRQTMCGFPHLRNLPVIDLDRPEEAAAVIRHLLSVPETLKAVQQRQTAHQAAFIASQSDVWSRTLREIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZG9</accession>
    <name>A8HZG9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YceI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yceI</name>
        <name evidence="2" type="ordered locus">AZC_4582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4582"/>
    <dbReference type="EnsemblBacteria" id="BAF90580">
        <property type="protein sequence ID" value="BAF90580"/>
        <property type="gene ID" value="AZC_4582"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4582"/>
    <dbReference type="eggNOG" id="COG2353">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_071003_1_1_5"/>
    <dbReference type="OMA" id="RFSYSHF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YceI" evidence="1">
        <location>
            <begin position="59"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="225" mass="24110" checksum="372F3DB2C520869C" modified="2007-12-04" version="1">MMRMALTQRELRRGDALRTSLMPAFASRAFFLVFLALSATPLAAQTPDTTDPKAVRSGTYALDAGHTRVVWSLSHRGFSTYSGLLPAASGMLVLDPAKPEASRVEVTLNSADVATADPRFDPRLKGPDYFNAAAFPTLTFASSAVKVEGSRAQVTGTLTFLGQSRPVTLDVTFHKAGINPTDKLYHVGFDATGTLTRSDFGLKTGLPGIGDAVKLQIEAEFTQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZP0</accession>
    <name>A8HZP0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4608</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <sequence length="151" mass="17071" checksum="41905DC7F392F247" modified="2007-12-04" version="1">MVVRLSPTDLLTIHYGVWDQANPGDRRDAGMLAPLDVFVNLRTPGWGLHASFKDEQRDLGRMGRLEIIVHDLERHIHVWQTRLDATKGVRVTKDQRRGKSEVETPMSDTEMAPWLTPVFPFGDYWTLLRRIEACARLAGHGPLPGVPPLAS</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
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                <person name="Liu CT."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1225"/>
    <dbReference type="EnsemblBacteria" id="BAF87223">
        <property type="protein sequence ID" value="BAF87223"/>
        <property type="gene ID" value="AZC_1225"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1225"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="VRCTIRD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="7">
        <location>
            <begin position="344"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="413"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="590"/>
            <end position="652"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="694" mass="73061" checksum="85450BD000A6C9A9" modified="2007-12-04" version="1">MRIRGMILLCISTLGAVSLVGGVVVAVNQWQRWNSAVAVEGLMQVFAEMAYINERYSIERGDFNQMLLADTPVTPTLQETMRRNLGRTDEALANAKANAAKLPAADRQAFEGPIQKTIDEIRQLREASWPQGEKPKAARDPAFVQSFVPKAQDILQSLGRTAAALELRISDEDNNVGRLAAFARQTIFLRDAAGRRATMVTTLLGSGKPFTPAQLEQFFQLDGQVTAYWDMVSHASKDLNDVPGITTAMTEAKTKFTDLVANLNRSMMPAAKGEGPAPMPLADWRAQISPALKSSLAPRDAAFTAAYVMAEASIASARTGFALACGGIVGIIAIVGGFALFINRRLITPIRGLTVGIEQIAEGNLDVDIPGAGRKDEIGEISRAVEVLRGNSREVVRLQEEQVAMREQAEQDRRATFARVADELDRVVGKIAGAVSATSEELQASARGMSTMAAQTSDRSSVAAQASHVASDMVGAVAAAAEELSASVNEIGTQVKESARIAGVAVDEANNAASKVTAMSEAARKIGDILQLITEIAGQTNLLALNATIEAARAGEAGKGFAVVASEVKNLADQTAKATAEIDTQISAVQSATNEAVSAIASIAGTIGRMNDISGSIASAVTQQQAATSEIAGSIARASEGTREANENMAQVTQTAAETGSAASQVLDASTELSRTSSELRVATDDFVARIRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0D7</accession>
    <name>A8I0D7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169776.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1245"/>
    <dbReference type="EnsemblBacteria" id="BAF87243">
        <property type="protein sequence ID" value="BAF87243"/>
        <property type="gene ID" value="AZC_1245"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1245"/>
    <dbReference type="eggNOG" id="COG0454">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1529546_0_0_5"/>
    <dbReference type="OrthoDB" id="2055010at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="26"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="175" mass="18676" checksum="E8A435929F6FE6E4" modified="2007-12-04" version="1">MSVGPVIRRAGPVDARRLGAAGPALYAESYAFLWDDDAAYAAQLATFGPDAFADLLARDDARVWLVEDDGALLGFLSLLLGVPEPVTGRSAGAEVPRIYLARAATGQGLGRRLLDEAAACARDEGAGYLWLDAMETAPWAVRTYQKWGFAEIGRMPFGRPVKAGHGTLVVLSRDL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0R2</accession>
    <name>AZOR_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FMN-dependent NADH:quinone oxidoreductase</fullName>
            <ecNumber evidence="1">1.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Azo-dye reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">FMN-dependent NADH-azo compound oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">FMN-dependent NADH-azoreductase</fullName>
            <ecNumber evidence="1">1.7.1.17</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">azoR</name>
        <name type="ordered locus">AZC_1287</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.</text>
    </comment>
    <comment type="function">
        <text evidence="1">Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 a quinone + H(+) + NADH = 2 a 1,4-benzosemiquinone + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:65952"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="ChEBI" id="CHEBI:134225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>anthranilate + N,N-dimethyl-1,4-phenylenediamine + 2 NAD(+) = 2-(4-dimethylaminophenyl)diazenylbenzoate + 2 H(+) + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:55872"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15783"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:71579"/>
            <dbReference type="EC" id="1.7.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="1">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the azoreductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.-" evidence="1"/>
    <dbReference type="EC" id="1.7.1.17" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169818.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I0R2"/>
    <dbReference type="SMR" id="A8I0R2"/>
    <dbReference type="STRING" id="438753.AZC_1287"/>
    <dbReference type="EnsemblBacteria" id="BAF87285">
        <property type="protein sequence ID" value="BAF87285"/>
        <property type="gene ID" value="AZC_1287"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1287"/>
    <dbReference type="eggNOG" id="COG1182">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_088964_0_0_5"/>
    <dbReference type="OMA" id="SGMINFG"/>
    <dbReference type="OrthoDB" id="1402654at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016652">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01216">
        <property type="entry name" value="Azoreductase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023048">
        <property type="entry name" value="NADH:quinone_OxRdtase_FMN_depd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0285">Flavoprotein</keyword>
    <keyword id="KW-0288">FMN</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000073117" description="FMN-dependent NADH:quinone oxidoreductase">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="16"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01216"/>
        </source>
    </evidence>
    <sequence length="206" mass="21750" checksum="C5446CEB361B77FE" modified="2007-12-04" version="1">MTSILLVTSSPRGADSLSTRFATEIAEGLKARFGGALLTRDLAANPPPHITQAYIHGRVTPPEARTPEQVEAVALAQEFVDEVKAADVIVLGSGMINFGPSSQLKAWFDHITWPGVTFGYGEAGRPQGTLTGKKVYLVTAAGGVFSEGDWAPFDFQTGNLRHLLGFVGLTDVEIIRVEGTVFGPEAAKAAIAATEAQVRSILETAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1S2</accession>
    <name>A8I1S2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_1414</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169942.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="SMR" id="A8I1S2"/>
    <dbReference type="STRING" id="438753.AZC_1414"/>
    <dbReference type="EnsemblBacteria" id="BAF87412">
        <property type="protein sequence ID" value="BAF87412"/>
        <property type="gene ID" value="AZC_1414"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1414"/>
    <dbReference type="eggNOG" id="COG3485">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046727_1_1_5"/>
    <dbReference type="OMA" id="PWHLMTY"/>
    <dbReference type="OrthoDB" id="1456634at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018576">
        <property type="term" value="F:catechol 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009712">
        <property type="term" value="P:catechol-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03461">
        <property type="entry name" value="1_2-HQD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039390">
        <property type="entry name" value="1_2-HQD/HQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007535">
        <property type="entry name" value="Catechol_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04444">
        <property type="entry name" value="Dioxygenase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dioxygenase_N" evidence="8">
        <location>
            <begin position="22"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="INTRADIOL_DIOXYGENAS" evidence="7">
        <location>
            <begin position="101"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF87412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="293" mass="32298" checksum="AC8CBA51065230FA" modified="2007-12-04" version="1">MRNFDQFTITQAVLERVANTPDARTRQISEALVRHLHDFIREVRPTQAEWEQGIAFLTATGHMCTGTRQEFILLSDTLGVSMLVDAINHDHQQAVTESTVLGPFYVEGPPEQPCGSDISGDLPGEPMFASGTVRTADGTPLANAIVDVWHSDEDGYYDVQHEGEGLVARARFRTDEAGHFHFWSIKPAAYPIPHDGPVGKMLQAQGRHPWRPAHVHFMIEAPGYEKLVTHVFVAGDAYLDSDAVFGVKDSLICDFAVHPAGAAPDGRVVDRPWCELTYDFRLNPVSNAASRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1X8</accession>
    <name>A8I1X8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative NAD-dependent epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4677</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T.T."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
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                <person name="Liu C.T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1927"/>
    <dbReference type="EnsemblBacteria" id="BAF87925">
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    <dbReference type="KEGG" id="azc:AZC_1927"/>
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        <property type="entry name" value="Solute-binding_3/MltF_N"/>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723294" evidence="2">
        <location>
            <begin position="24"/>
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    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="40"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <sequence length="307" mass="32383" checksum="61C1E32EFA8E680F" modified="2007-12-04" version="1">MPVGTLMKALAGIAVAVSWVALAGPVLADSRVDAIRQTGTITLGHPETSVPFAYLDGNQKPVGYTVEICEKIAGEIKSALNLPKLDIRYNPTTSATRIPLLANGTIDLECGNTTNNVERHKLVAFAPTTFVAQVVLMARKDGGVDVNNPASFRGKTIAAQAGGQTFKVISQINAKGNYGITVAGAKDTGEAFLMVETGRAAGTANDDGLAYGQVASSKTPDAFIIGTKSLEIAPYGIMEPKDDPEFKKLVDDAVLKLIKDGTVAALYDKYFNAPIPPRGINLKYPMSDALKRALAKPTDSGDPADYQ</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="45"/>
            <end position="68"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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        <location>
            <begin position="109"/>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
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    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="308" mass="32916" checksum="DB48499DCF5A8147" modified="2007-12-04" version="1">MSLANDHPGAAPPEGLAIATELPDILKARKPRTGFIGFLRRHPTIAIGGALLLVLIFIAVFAPYLGTVDPSALSPARRTRAPSAQYWFGTDMLGRDIYSRVLYGTRVSLIVGFAVAFFASLGGLAIGLIAGYVRWLDSLVMRVMDSLMSIPPILLAVSLMAITRGSVGNVILAITVAEIPRVSRLVRGVVLSLREQPYVDGAIASGTRTPMIILRHILPNTLAPMTVQATYICGSAMIVEAILSFIGAGTPPNIPSWGNIMAEGRALWQVKPFIVFFPAAFLSVTVLAVNLMGDGLRDMLDPRQAKGV</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:16229"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58332"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.7.7.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CDS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.41" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1698"/>
    <dbReference type="EnsemblBacteria" id="BAF87696">
        <property type="protein sequence ID" value="BAF87696"/>
        <property type="gene ID" value="AZC_1698"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1698"/>
    <dbReference type="eggNOG" id="COG0575">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037294_1_1_5"/>
    <dbReference type="OMA" id="PKFWPRV"/>
    <dbReference type="UniPathway" id="UPA00557">
        <property type="reaction ID" value="UER00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004605">
        <property type="term" value="F:phosphatidate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016024">
        <property type="term" value="P:CDP-diacylglycerol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000374">
        <property type="entry name" value="PC_trans"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01315">
        <property type="entry name" value="CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="246"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF87696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="272" mass="27773" checksum="4CC7A6A2C28E3645" modified="2007-12-04" version="1">MIPVVIGPDLKQRTLSAIVLAPVVLATTVFGGLPFLLLWTLAGTGVLLEWCGVARLSPRVPYLAIGFVVIAACAGLKAVGLPESVPLVLLVGLAVCALLVRPRLWAALGLVCAAACAFPVVVLRGDDQVGLLSVFFLFAVVWGTDIGAYFTGRIVGGPKLWPRLSPNKTWSGAIGGAVFGTLAGTGVALAGGLLFSPVLFLIGLLLSVISQSGDLAESAFKRAFGVKDAGWLIPGHGGILDRLDGFAAAALAALVIAVLHGGPTPAAGLLLW</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I485</accession>
    <name>LPXD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="1">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lpxD</name>
        <name type="ordered locus">AZC_1702</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170230.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I485"/>
    <dbReference type="SMR" id="A8I485"/>
    <dbReference type="STRING" id="438753.AZC_1702"/>
    <dbReference type="EnsemblBacteria" id="BAF87700">
        <property type="protein sequence ID" value="BAF87700"/>
        <property type="gene ID" value="AZC_1702"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1702"/>
    <dbReference type="eggNOG" id="COG1044">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049865_0_2_5"/>
    <dbReference type="OMA" id="QIQIAHN"/>
    <dbReference type="OrthoDB" id="1602061at2"/>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000072492" description="UDP-3-O-acylglucosamine N-acyltransferase">
        <location>
            <begin position="1"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <sequence length="357" mass="36160" checksum="2C3D1C19D0F08271" modified="2007-12-04" version="1">MSEPAFFPLPTPLTLDEVAALSGARLARPGAQDALRLTGVGTLADAGPSELAFLDQSRYLATLGTARAGAIITSEKFAGEVPEAIAVLVSPRPASAFVAVTRQLFPQALRPQPVFGHTGIAPGAFIHPTASLEAGVTVDPGAVIGPGAEVGAGSVICANAVVGAGVRIGRDSTIGAGVSLSHALVGNRVIVHAGARIGQDGFGYQPGPGGHLKVPQIGRVVLQDDVEVGAGSTIDRGALRDTVIGEGTKIDNLVQIAHNVVIGRHCIIVSQTGISGSTTLGDFVMLGGQVGVVGHCTIGDGAQIAASSNVKGDVPPGVRWGGSPAKPVREWFREMTTLKKLAESRARSGAATPGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4H5</accession>
    <name>A8I4H5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1732</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87730.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1732"/>
    <dbReference type="CAZy" id="GH3">
        <property type="family name" value="Glycoside Hydrolase Family 3"/>
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    <dbReference type="EnsemblBacteria" id="BAF87730">
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        <property type="gene ID" value="AZC_1732"/>
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    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="35"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    </evidence>
    <sequence length="342" mass="36371" checksum="92FE1750EDA66451" modified="2007-12-04" version="1">MTFAPSGTRALIVGLSGLRLTEGERDFLRAVRPWGLILFARNVDTPEQVAHLVAEGREVLGWRAPVLIDQEGGRVQRLRPPFWIDYPPAEQFGAIYKADKARALKAVHLNSRLIAADLAALGIDVDCLPVADLRLPEGHGVIGNRAYGSEPSTVAALASAAARGLMEGGVLPVLKHIPGHGRAPADSHEHLPTVTASRSELEATDFAAFMSLNTLPLGMTAHVVYAAIDKHNPATTSRVVLDDVVRGFIGFDGALMSDDLSMKALSGSFAERARASIAAGCDLLLHCNGQMDEMRAVASESPLLAGAAAERAARALARRIDPPATDLDAIRDELAVLLEQPV</sequence>
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    <accession>A8I4R0</accession>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
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                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
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    <evidence type="ECO:0000313" key="5">
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    </evidence>
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        <source>
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    <sequence length="249" mass="27815" checksum="DE3C60152B7D95AB" modified="2007-12-04" version="1">MEPVTQSLLYLDNISVVFDGFRALNKLSLTIEEAEMRAIIGPNGAGKTTMMDVITGKTRPTAGEAMFAGIHDLTTMDEADIAQLGIGRKFQTPTVFDMHTVEDNLLLAVKSDRRAFANITWRRTAHERARIDELLERIRLKDQRHRQAAELSHGQKQWLEIGMLLAQEPRLLLVDEPAAGMTDQETADTAELLRDIAKTRSVVVVEHDMQFVRDLGVKVTVLHEGSVLAEGSLDQVSANERVIEVYLGR</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Akiba N."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the thymidylate kinase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3 6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170700.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2173"/>
    <dbReference type="EnsemblBacteria" id="BAF88171">
        <property type="protein sequence ID" value="BAF88171"/>
        <property type="gene ID" value="AZC_2173"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2173"/>
    <dbReference type="eggNOG" id="COG0125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049131_0_0_5"/>
    <dbReference type="OMA" id="VMTREPG"/>
    <dbReference type="OrthoDB" id="1585072at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="8">
        <location>
            <begin position="11"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="235" mass="24490" checksum="9A83B44D077F2252" modified="2007-12-04" version="1">MSSARGRFITLEGGEGTGKSTQARRLAAALQKGGLEVVLTREPGGSAGAEAVRHVLLSGAAKDFGPQGEALLFAAARADHVDSLIRPALAAGKWVICDRFIDSTRVYQGAVGAVPGALLDSLEWVAAAEARPDLTLVLDVPPEVGLSRAAGRGEGADRFESEGLAFHTRVRDAFLALAKADPARCVIVDASGGPDDVAALVWSSVRERLVPPERPLSAKPAATRKPAGSGRRRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I860</accession>
    <name>A8I860_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">ATP-binding component of ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2214</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170741.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2214"/>
    <dbReference type="EnsemblBacteria" id="BAF88212">
        <property type="protein sequence ID" value="BAF88212"/>
        <property type="gene ID" value="AZC_2214"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2214"/>
    <dbReference type="eggNOG" id="COG1127">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="RMKDFDA"/>
    <dbReference type="OrthoDB" id="1058434at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="22"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="270" mass="29684" checksum="F354929700100D1D" modified="2007-12-04" version="1">MDAPAPPPVPQRRRQLSREVIISVRDIVVGFGERVILNHLDLDVYKGEILGFVGTSGGGKSVLTRTILGLVPKTSGKVEVFGQDLDHLNERERSALERRWGVLFQQGALFSSLTVKQNIQFPLRETLRLSQRMMDEIAFAKIEMVGLKPDVAEKLPSELSGGMIKRAALARALALDPEIVFLDEPTSGLDPIGAGDFDELIRTLQQTLGLTVFMVTHDLDSLHTVCDRIAALADGKVIAQGTIETMMAAQHPWLRAYFHGARARAVQAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8N9</accession>
    <name>A8I8N9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type III effector Hrp-dependent outer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2686</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the four-carbon acid sugar kinase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_2686"/>
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        <property type="protein sequence ID" value="BAF88684"/>
        <property type="gene ID" value="AZC_2686"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <keyword evidence="6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
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        <location>
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        <location>
            <begin position="268"/>
            <end position="421"/>
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    </evidence>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022777"/>
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            <dbReference type="Pfam" id="PF17042"/>
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            <dbReference type="EMBL" id="BAF88684.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the desulfonation of aliphatic sulfonates.</text>
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    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an alkanesulfonate + FMNH2 + O2 = an aldehyde + FMN + 2 H(+) + H2O + sulfite</text>
            <dbReference type="Rhea" id="RHEA:23064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:134249"/>
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        </reaction>
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    <comment type="similarity">
        <text evidence="1 6">Belongs to the SsuD family.</text>
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    <dbReference type="InterPro" id="IPR011251">
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    <dbReference type="Pfam" id="PF00296">
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    </dbReference>
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    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="348"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88711.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="405" mass="44242" checksum="6BBA6EF05E1BD655" modified="2007-12-04" version="1">MTISFLTAFWGETECPMSNLTPPPPHMFWFIPTHGDGSYLGSETRQRPPEFGYFREVATAVDRLGFEGVLLPTGQSCEDSWITAAGLATATERLRFLVALRPGVTTPVFAARQTAALDRLSDGRLLLNLVVGGHPGELAADGVFLGHDERYAQGAEFVAIWRALVRGETVNHEGRYYRVENGRLDFPVVQEHLPLYFGGSSDAGLDVAAEHVDLYLSWGEPPALLAEKIATARARAAARGRTLRFGIRLHFIVRETESEAWTAAERLISQVSDAQIANAQKRFKEEMDSVGQARMAALHDGRRDRLEVAPNLWAGVGLVRRGAGTALVGDPQTIAARIREYQAVGVDTFIGSGYPHLEEAYRVAELLFPALGIDGRRRGVRTQIVNEFAVGSHGPAANATIRAAE</sequence>
</entry>
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            <fullName evidence="7">High-affinity Fe2+/Pb2+ permease</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171267.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2743"/>
    <dbReference type="EnsemblBacteria" id="BAF88741">
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    <dbReference type="OMA" id="WYGTLLK"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0033573">
        <property type="term" value="C:high-affinity iron permease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="FTR1/Fip1/EfeU"/>
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        <property type="entry name" value="FTR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="171"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="287" mass="29761" checksum="F61AFEA15F9A668F" modified="2007-12-04" version="1">MLAAFVIVFREVLEAGLIVGVMLAASEGVRGRGAVISAGILGGAIGSAVIALFAEQIANLFEGSGQELLNAAILSVAVVMLVWTVVWMASHGREMVIEMRALGGDVKAGRRPLAALGLVVGMAVLREGVEIVLFMYGIAITGGETPLNVFFGFMLGVAAGGAVSFLLYRGLVSIPVKHLFKTTTVLITLLAAGLSAQVVGILQDSGFIQSLADPLWDSTWLLADDSAVGRVLRTLVGYRAQPTGMQLIAYAATVAVIVGLSVAVNGRLARAKAAAPVRHTPMLQPGE</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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        <property type="gene ID" value="AZC_3071"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3071"/>
    <dbReference type="eggNOG" id="COG4783">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030556_2_0_5"/>
    <dbReference type="OMA" id="HLSQRHF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="96"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="483"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF89069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="511" mass="55193" checksum="2DA02A614FED54D6" modified="2007-12-04" version="1">MGRGNAPPHCRQGAGATRRMVQEDDRAPFVGDRLLVMFASRAVCPTRVLRRASSVALSLIASCHLALAPAQAQEKSGRGLPTIRDTEIENLLRDYTRPILRAAKLAQQNIEVVLVNDRSFNAFVADGRRIFINTGALVDSTTPNQIIGVLAHETGHIAGGHLARRREQLAGAQTMAIVAMMLAAGGVAAGAASGANGGNMGNAAAGAVMAPQEMIRRSLLAYQREEEQAADRSAVTYLNATQQSAKGMLETFERFQNDQLFLTQRTDPYLLSHPMARERIAALEVLAKASPYFNAKDPPALQHRHDMMRAKLIGFQERPDVVARRYPPTDQSLPAQYARAISAYRFASMSGAVAQIDALIAKEPGNPYFQELKGQALLESGRASEAVPPLRKAVAMTDGAPLIRAMLGQALVETGNAGMMDEAIRELTFSTQRDPDNASGWRALAKAYGFKNNRPQADLASAQAALATGDVRTARELAARARQTFPPNSPGWLKADDIVNIKPPQSSDNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBU0</accession>
    <name>A8IBU0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="12">ATP-PRT</shortName>
            <shortName evidence="12">ATP-PRTase</shortName>
            <ecNumber evidence="5 12">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hisG</name>
        <name evidence="14" type="ordered locus">AZC_3118</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ATP phosphoribosyltransferase family. Short subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="5 12"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171642.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3118"/>
    <dbReference type="EnsemblBacteria" id="BAF89116">
        <property type="protein sequence ID" value="BAF89116"/>
        <property type="gene ID" value="AZC_3118"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3118"/>
    <dbReference type="eggNOG" id="COG0040">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038115_0_1_5"/>
    <dbReference type="OMA" id="LDIHNTR"/>
    <dbReference type="OrthoDB" id="1419568at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 12 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 12" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="13">
        <location>
            <begin position="56"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAF89116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="326" mass="34925" checksum="20754B68382232D1" modified="2007-12-04" version="1">MSDTLILAVPSKGRLQENVHAFFARAGMPLVQARGAREYRGALGGVDNVEVAYLSASEIAAALASGAVHVGVTGEDLVRENIPDADKRVMLLEKLGFGHANVVVAVPQAWIDVRSMEDLDDVAGHFHARTGRRIRVATKYVNLTRSFFARHGIVDYRIVESAGATEGTPAAGSAELIVDITTTGATLAANALKVVDDGVMLRSEANLVASLTAPWGEAQHAAARAMFDRMAAEKRARTMREVRTRFIQCDTNLVDEAVSRFRCVAPFGGPTSSGMLTLHCPPDTLHALSLFLRERGASMVTVGPIEYVFAAENPLYEALQARLAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC47</accession>
    <name>A8IC47_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_3160</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein SsuA/TauA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171684.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3160"/>
    <dbReference type="EnsemblBacteria" id="BAF89158">
        <property type="protein sequence ID" value="BAF89158"/>
        <property type="gene ID" value="AZC_3160"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3160"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_2_0_5"/>
    <dbReference type="OMA" id="YQLKLIP"/>
    <dbReference type="OrthoDB" id="785019at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010067">
        <property type="entry name" value="ABC_SsuA_sub-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01728">
        <property type="entry name" value="SsuA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724371" evidence="4">
        <location>
            <begin position="34"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="5">
        <location>
            <begin position="37"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="322" mass="34183" checksum="1B56D3EF10CEF54A" modified="2007-12-04" version="1">MSHTNNPFSVTRRRFGALAAGTLVAGWSAGAHAQEKVVRIGYQKYGTLILLKNKGLLEAKLKPLGYAVRWAEFAAGPQLLEALNAGAIDFGNTGEAPPIFAQAAGAPLVYVGYEPAAPEGEAILVPKNSPLKTVADLKGKTVALNKGSNVHYLLVKALETANVSYTDIKTAFLTPADARAAFERGAVDAWAIWDPFQAAAETTIEARQLTNGTGIVSNYQFYFSTQSFVEKAPDVVDAVLAGVAEIGAWVKANPKAAAAEFSPLIGIPAPILEIALARQQYDVKPITPAVVAQQQQVADAFFKLGLIPKEIRISDAVRALKS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID91</accession>
    <name>COBS_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="1">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cobS</name>
        <name type="ordered locus">AZC_2896</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CobS family.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171420.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ID91"/>
    <dbReference type="STRING" id="438753.AZC_2896"/>
    <dbReference type="EnsemblBacteria" id="BAF88894">
        <property type="protein sequence ID" value="BAF88894"/>
        <property type="gene ID" value="AZC_2896"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2896"/>
    <dbReference type="eggNOG" id="COG0368">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057426_1_1_5"/>
    <dbReference type="OMA" id="GHTGDTY"/>
    <dbReference type="OrthoDB" id="1996371at2"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000072776" description="Adenosylcobinamide-GDP ribazoletransferase">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <sequence length="264" mass="26540" checksum="F61BA90723447965" modified="2007-12-04" version="1">MRHSRILADVGAALRFYSRIPVPAGAAEDAFAPPDLKRIAYAVPLAGAAIGLAGAAILIGAHALGLPNLVAAILAVLTCVLLTGALHEDGLADTADGFGGGASRLRRLEIMRDSRIGSYGACALVFSLLLRVALLDGLLALSPTRAALALIAAASLSRAAGMLLLEFLPPARADGASAAAGQPGADAAVRSALVGALLATLLIVPSTGVGATLMAIGLSVLALFAMTRLSNRLIGGQTGDVAGAVQQLCEIAFLMGVLIYARPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDV1</accession>
    <name>A8IDV1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpiR</name>
        <name evidence="3" type="ordered locus">AZC_2997</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Gevers D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF89587">
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        <property type="gene ID" value="AZC_3589"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3589"/>
    <dbReference type="eggNOG" id="COG0209">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_002384_0_0_5"/>
    <dbReference type="OMA" id="FHCNLAE"/>
    <dbReference type="OrthoDB" id="357568at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR040763">
        <property type="entry name" value="RNR_alpha_hel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013345">
        <property type="entry name" value="RTP_Rdtase_AdoCbl-dep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17975">
        <property type="entry name" value="RNR_Alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02505">
        <property type="entry name" value="RTPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="11" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNR_Alpha" evidence="12">
        <location>
            <begin position="8"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF89587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="664" mass="74448" checksum="37481C859C9145CD" modified="2007-12-04" version="1">MTTPTTRAEVIARRTYNRPLDTQGATFETWGETIARVISHQTWLWERAKGGPLSAEECAELEELRELMNSRKVLPSGRTLWLGGTEIAKRREASQFNCSFARIETVHDIVDAMWLLLQGCGVGFEPVVGTLNGFSRPVRVEVVRSENRTTKGREENLETFTEEHGEKVWTISLGDSAEAWAKAAGKLLANKRPVDVLRLDFREIRAPGIRLSGYGWISSGDVTISKAFVAIAEILNRRAGQLLSRIDILDIVNWLGTTLSSRRSAEIAVVPFDDREWQEFATAKKDHWIGNPQRAQSNNSLLFYRKPAKNELRQIFDLMQDAGGSEPGFINAVAALKRAPWFKGVNPCAEILLGNKSFCNLVETDLGAFNGNLAGLHRAIRLVARANYRQTCVSFLDGILQRSWHELNEFLRLCGVGLTGIVRWEHRDDGAAFRELRRIAHEGANGMADELGLPRPKVVTTVKPSGTLSKVMDTTEGVHKPLGRFIFNNVRFSTHDPLVPVLEQAGYRVFPDPYAGDAVLVTFPVDYSDVAFDECTVLREGELVKVEVNTESAIEQLERYKLLMDNYVDHNCSITVSYSPDEVEDIIDWIDRNWDSYVGVSFIYRNDPTKNAKDLGYPYLPQEVVTEEVFRSYVSGLRPVDINQGNSFEELSEDGCASGACPVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG29</accession>
    <name>A8IG29_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">NMT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0026</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0026"/>
    <dbReference type="EnsemblBacteria" id="BAF86024">
        <property type="protein sequence ID" value="BAF86024"/>
        <property type="gene ID" value="AZC_0026"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0026"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028871_1_1_5"/>
    <dbReference type="OMA" id="DWKFEGP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721008" description="NMT1 domain-containing protein" evidence="1">
        <location>
            <begin position="38"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="54"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="352" mass="38211" checksum="AB8EC8460C3629BB" modified="2007-12-04" version="1">MCLASCQRTGGRPMRHMLRGLIGALGFIAAAALPARADTDIKFALDWKFEGPSAPYFVAIDKGYYKAEGLNVTVDTGPGSVAGIARVAAGTYPLGFFDINSLVKFNDQNPDKALKAILMVYDKPPFSIVTLVKTGISKPKDLEGKVLGAPAPDGAYAQWKAFVKENAIDADKVKIENVGFPVREPMLADGKVDAITGFSFSSYFNLLQKGLKPEDIKVLLMSDYGLVLYGNAVIVNPDFAKAHPKEVAGFVRATIKGIIETARDPEAAIKSVMKRNETGDEKIELARLKMALKDNMITEWVTKNGIGGIDVDRMTKSIEQIAVTYDFKEKKPAAADIFTAEFLPPAAERMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH94</accession>
    <name>A8IH94_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Plasma membrane-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_0191</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF86189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_0191"/>
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        <property type="entry name" value="HAD-like_sf"/>
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        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01647">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-type"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="318"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="676"/>
            <end position="697"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="703"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <end position="766"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="786"/>
            <end position="803"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
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            <begin position="815"/>
            <end position="837"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="843"/>
            <end position="868"/>
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    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="10">
        <location>
            <begin position="54"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="33"/>
            <end position="52"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00831"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="891" mass="94584" checksum="C609253F8C3E3496" modified="2007-12-04" version="1">MRVTLFTMTRRVRRRSGEIGVRGLAMSQSVAAAPAISGRTPPAKAKPADGGSSRLDADAIAAKFAELSSSPQGLSSADAARLHQTYGPNTIAAHEESRWSKLLGYFWGPIPWMIEAAALLSLIRLDWPDFIVVMGLLLYNAVVGFWQDSKAASALAALKKGLALKARVLRDGNWITVDTSDLVPGDVVSISGGETLPADLILTEGKYLSVDQAALTGESLPVSKSVGDSGYSGSIVRQGAMTALITATGNATFFGRTAKLVASAGAKSHAEKAVIQMGDFLIILSAALALLLVVAQVHRDIVAEGHWEWAHAGAIVQLVLVLLVASVPVATPAVMSVTMALGALALSKQQAIVSRLSAIEELAGVDVLCSDKTGTLTMNQLTLQPPIPWGSAAPDELILGAALASQKQSADAIDKAVLAGLKDPKVLDQYRQVDFTPFDPVSKKTAAAVAGPDGKTVHYAKGAPQVIAALCGLGPDGGNAYFDAVAKLAHDGTRALGVARSDDGTHWTLLGLLPMLDPPRPDAAATIAHAQKLGIAVKMVTGDDVAIGSEISRQLGLGDHLLVAGEVFGEDANPEHIAIDAVRAVEVADGFGRVFPAHKFEIVKALQEGGHIVAMTGDGVNDAPALKQADCGVAVSGATDAARSAAALILTAPGLSTIIAAIMEARAIFERITSYIYYRIAMTLNIMLVVVLTYLVYNFMPLTAIMIVVMALLDDIPIMTIAYDNVKVQDRPVRWNMHRIISFSTVMGIMALVQSFGIVMLGMFWMKSPGLTAILPMDQAHVQTMLFLQLAAGGHLLFFVSRVQGTLFKPPYPSLPVMGAVMGTQVFAIFMCAFGWFMPALPWLLIGIVWVYCLVWTLIMDLVKLLYFHMVDRRDRQRSIIDSSIGPAMPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHH8</accession>
    <name>A8IHH8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Altronate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3278</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UxaA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171801.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3278"/>
    <dbReference type="EnsemblBacteria" id="BAF89276">
        <property type="protein sequence ID" value="BAF89276"/>
        <property type="gene ID" value="AZC_3278"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3278"/>
    <dbReference type="eggNOG" id="COG2721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029189_0_0_5"/>
    <dbReference type="OMA" id="WVHEHNV"/>
    <dbReference type="OrthoDB" id="889365at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007392">
        <property type="entry name" value="Gal/Altron_deHydtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04295">
        <property type="entry name" value="GD_AH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="3">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="507" mass="53782" checksum="B6C2B3B4594819BF" modified="2007-12-04" version="1">MSSPRTLRLHETDNVVIVLDTVARGAALAGGLTAAGPVPRGHKIAAAPIPAGAPVRKFGQVIAFARTDIAPGEWVHEHNVMLQDFERDYAFASEARAPEGLLPGEMPATFEGFRRADGRAGTRNYIGILSSVNCSATVADYIADEVTRSGILADYPNIDGVVPFTHGTGCGMGSKGEEFDILARTQWGYATHPNFAAVLVIGLGCEVFQIPRLKEAYGIVEGEHFQSLTIQESGGTRKSVAAGVARVKEMLAFANSSRRQTVAASELMLALQCGGSDGYSGLTANPALGAAVDILVRQGGTAILSETPEIFGAEHLLTRRAESEAVGRKIVDLIDWWTDYAARAGGELNNNPSPGNKAGGLTTILEKSLGAVAKGGTSTLRGVYRYAERIDRKGFVYMDTPGYDPVAATGQVAGGANVLCFTTGRGSAYGCKPTPSIKLATNSDLYRRMEEDMDLNCGDVLEGVSIEEKGREIFQTVLDVASGTRSKSELLGYGRNEFVPWQLGAVM</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHS4</accession>
    <name>ACCA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha</fullName>
            <shortName evidence="1">ACCase subunit alpha</shortName>
            <shortName evidence="1">Acetyl-CoA carboxylase carboxyltransferase subunit alpha</shortName>
            <ecNumber evidence="1">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">accA</name>
        <name type="ordered locus">AZC_3315</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AccA family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171838.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IHS4"/>
    <dbReference type="SMR" id="A8IHS4"/>
    <dbReference type="STRING" id="438753.AZC_3315"/>
    <dbReference type="EnsemblBacteria" id="BAF89313">
        <property type="protein sequence ID" value="BAF89313"/>
        <property type="gene ID" value="AZC_3315"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3315"/>
    <dbReference type="eggNOG" id="COG0825">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015486_0_2_5"/>
    <dbReference type="OMA" id="TPWQRVQ"/>
    <dbReference type="OrthoDB" id="886663at2"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00823">
        <property type="entry name" value="AcetylCoA_CT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001095">
        <property type="entry name" value="Acetyl_CoA_COase_a_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42853">
        <property type="entry name" value="PTHR42853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03255">
        <property type="entry name" value="ACCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01069">
        <property type="entry name" value="ACCCTRFRASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00513">
        <property type="entry name" value="accA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword id="KW-0276">Fatty acid metabolism</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000072879" description="Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha">
        <location>
            <begin position="1"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="39"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01137"/>
        </source>
    </evidence>
    <sequence length="317" mass="33707" checksum="2CF11EFE090EB712" modified="2007-12-04" version="1">MRSYLDFEKPVAELEAKVEELRALSSPDDGVSIADEVQKLEGKAQEALTQLYASLTPWQKTLVARHPARPHFSDFAKGLFTDFTPLAGDRKYGEDEALIGAFARFRGEAVCVLGHEKGSTTETRIRHNFGMARPEGYRKAVRIMELADRFGLPLISLVDTAGAYPGIGAEERGQAEAIARSTDAGLGLGVPNVAVVIGEGGSGGAIAIAAANKVLMLEHAVYSVISPEGAASILWRDTSKAQEAATNMKITAQDLLRFGIVDDIVREPVGGAHRDPKAAIEATGNAIAEAMGSLAGLDADAVRKARRAKFLAIGRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHX2</accession>
    <name>A8IHX2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3333</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171856.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3333"/>
    <dbReference type="EnsemblBacteria" id="BAF89331">
        <property type="protein sequence ID" value="BAF89331"/>
        <property type="gene ID" value="AZC_3333"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3333"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_134269_1_1_5"/>
    <dbReference type="OMA" id="THSHPNE"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025499">
        <property type="entry name" value="KdgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029883">
        <property type="entry name" value="KdgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="43"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="115" mass="12425" checksum="3153B6E22F2A6FC8" modified="2007-12-04" version="1">MAQKGDVFAFAGETEVEVLDDIVSRQILTYNDEIMMVRVIFKKPGPGGVPHSHPHVQTTSVESGVFDITIDGKTARLKAGDSFYVPGGVHHGAICIEPGVLVDVFTPMRQEFVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8II31</accession>
    <name>A8II31_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dicarboxylic acid hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3355"/>
    <dbReference type="EnsemblBacteria" id="BAF89353">
        <property type="protein sequence ID" value="BAF89353"/>
        <property type="gene ID" value="AZC_3355"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3355"/>
    <dbReference type="eggNOG" id="COG3618">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064039_2_1_5"/>
    <dbReference type="OMA" id="FDTHVHV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="72"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="338" mass="36740" checksum="6696627815C502AD" modified="2007-12-04" version="1">MIIRPVKTGVQEETMNRVSRRACLATLGGAAAAASLPSFARAQNRTGADAPTILPPDPNTKTPAYKAPAGAVDAHTHIFGPGSKYPYAASRSYTPPDAPLEMFEALHAKIGIERAVLVNATVHGLDNRVITDAIAQSNGRYKGIANVDDTITDKELQALTDAGMKGCRFTFLGRLGGRPDMTKFHRIVDRIKAYGWHVDLYLEPEIIEEFVPILRALPLPYVIDHMGTVKASGGLEQKPFVALVELMRTDEKGWIKITGPERLSVAGSPFHDAVPFAQALIAAAPDRCLWGTDWPHPNVKVMPNDGVLVDLIPLYAPDVAQQHRLLVDNPVRLFGFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIN1</accession>
    <name>A8IIN1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3427</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3427"/>
    <dbReference type="EnsemblBacteria" id="BAF89425">
        <property type="protein sequence ID" value="BAF89425"/>
        <property type="gene ID" value="AZC_3427"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3427"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_4_0_5"/>
    <dbReference type="OMA" id="MEIMIHP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="43"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="180" mass="19613" checksum="C631885EDE02DA29" modified="2007-12-04" version="1">MQISAQVARSGPVTRGTRHRAVGFATPTPQGSRTVPADDIEVYAICHREAISPGEAKAFSLFRRHENGEARPFSIFVIRKSAREYVGYVNVCPHNRTWLNISSGGFLTADRARIACSRHRAEFDIESGTCLSGPCEGASLEPLALTIIAGDVCLCGVSLVEDESVREEPDETMEISIHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIR2</accession>
    <name>A8IIR2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3439</name>
    </gene>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="476" mass="52715" checksum="505BFB1BCC9C72DE" modified="2007-12-04" version="1">MSAWPVHATIDGPIVMIGFGSIGRGTLPLIERHFSFDLDRMVVIDPVDDDRKLLDARGIRYIQSEVTAENYRELLTPLLTNGAGRGFCVNLSVDVSSVAVMELCREIGALYVDTVIEPWKGFYFDPSLGTEARTNYALRESLLAARRRNPGGTTAVSTCGANPGMVSWFVKQALLNIAADTGLSLPEPKTREEWARFAQALGVKGIHVAERDTQRARNPKPRDVFVNTWSVEGFVSEGLQPAELGWGTHEKELPPDGRTHATGCGAAIYLTRPGADTRVRSWTPTPGPQFGFLVTHNEAISISDYYTVRDGEKVVYRPTCHYAYHPAGDAVLSLHEMFGSGGKMQSDWKILDEHEIVDGVDELGVLIYGHAKNAYWFGSQLSIEETRQLAPYQNATGLQVTSAVLAGMVWALENPQAGIVEADEMDFRRCLEVQMPYLGPVIGTYTDWTPLQSRNTLFAGDFDEEDPWQFKNVIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJG9</accession>
    <name>A8IJG9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0303</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168834.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0303"/>
    <dbReference type="EnsemblBacteria" id="BAF86301">
        <property type="protein sequence ID" value="BAF86301"/>
        <property type="gene ID" value="AZC_0303"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0303"/>
    <dbReference type="eggNOG" id="COG3411">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_126515_1_1_5"/>
    <dbReference type="OMA" id="WYHSATP"/>
    <dbReference type="OrthoDB" id="1412344at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="117" mass="12880" checksum="A4760A40681B593F" modified="2007-12-04" version="1">MTETATLSLTDVPQVYKRHVFACFQQRPPTHPRGSCGAAGAQPLWERLGKQIEATGQRDIVMTATGCMGFCQAGPIMVVYPEGVWYQPRTPEDVDEIVTTHLVGGTLVERLVIVPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJI6</accession>
    <name>A8IJI6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Parvulin-like PPIase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase plp</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Rotamase plp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_0311</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PpiC/parvulin rotamase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0311"/>
    <dbReference type="EnsemblBacteria" id="BAF86309">
        <property type="protein sequence ID" value="BAF86309"/>
        <property type="gene ID" value="AZC_0311"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0311"/>
    <dbReference type="eggNOG" id="COG0760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034646_1_3_5"/>
    <dbReference type="OMA" id="YEQAKPT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724502" description="Parvulin-like PPIase" evidence="9">
        <location>
            <begin position="29"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="10">
        <location>
            <begin position="158"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="278"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031484"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86309.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="314" mass="33255" checksum="63318F2794682883" modified="2007-12-04" version="1">MDHMMRPAPTAALAVALTAFAFGGQAFAQTAAPGATPPAAAAPARPADSDPVVETVNGAPIRASELAIAEDDIGPGLPQVQGAARQEYILSFLTDMTLLAQAAQAQKLDQSPEFAAKMNYLRTKALMETLMAAEAKKAVTEDAKRKTYDEFVKQTKPETEVHARHILVDSEAKAKEIAAKAKAGADFAKLAKENSKDSAEDGGDLGYFTKDQMVPEFADAAFKLDKGQVSDPVKTQFGWHVIKVEDKRQKPIPTYEQVSDQIDQYLIRKAQSDLVTKLRSDAKVEKTSAAPSAAPAAPATPAAPAGAAPAAPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKC2</accession>
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            <fullName evidence="7">Putative ABC transporter permease protein</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172408.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3888"/>
    <dbReference type="EnsemblBacteria" id="BAF89886">
        <property type="protein sequence ID" value="BAF89886"/>
        <property type="gene ID" value="AZC_3888"/>
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    <dbReference type="HOGENOM" id="CLU_039929_2_2_5"/>
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    <dbReference type="OrthoDB" id="974216at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="ABC_transp_permease"/>
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    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
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            <end position="86"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="290" mass="30104" checksum="B34455E106956DC0" modified="2007-12-04" version="1">MDLATLLFSALYQFGDAFAFLVLSACGLAVIFGMMGVINLAHGEFIMCGAYVSVSAARAGLPLPLAVLAGALASGLAGMVIERLVIRHLYERPLDTIVATWGISLIATQGTLILLGSSLQGIGTPLGGFQVGAYSYSLYRVVLFLSALAVLAALYALFNWTKFGVIARATIQVPHMAAALGVDTRLIYSLTFGLGAALAGLAGGLYAPTMTLVPTMGATFIMEAFVTVVVGGADVFLGTAPAAAILAIVKASMTSWQGQLFGQIGLLVTVIVVIRILPRGLSGFLLRERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKG0</accession>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3903"/>
    <dbReference type="EnsemblBacteria" id="BAF89901">
        <property type="protein sequence ID" value="BAF89901"/>
        <property type="gene ID" value="AZC_3903"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3903"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
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    <feature type="chain" id="PRO_5002721738" evidence="1">
        <location>
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            <end position="321"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="321" mass="34817" checksum="4872E2EA95A632AD" modified="2007-12-04" version="1">MRGRGGPLRGARMASRFFLTALLGLLAFASASAQEAAVTVHNESVPTLCAETDNVALTFAAPGISRLRIAAVHPAYIGTLSVDRMAPDFTACDMSKDPAVPAVPKRVTFFETPDLWLTGYTFPSFWRPAAVPFRVGDKVVEGLHLVQLWVRQQDRAEEVLVVYPPDGYWRARPLSPSHLPMTGYGSSFLVGPVETEGRPLVKLKEIAFDPATRIFTLTFAGGGTARMHLATLDREQLALDVTFDRPVAGAPFAALRSMYVTEFNADVARLAWKAPGEKGWGEAPVMTYPGGLASELWAGRLVPSRHNTSAPDMVFGPFGTK</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL72</accession>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
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        <source>
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    <sequence length="241" mass="24259" checksum="9ABE9337D5D31ABE" modified="2007-12-04" version="1">MKKGCGMTDATSHVRWGALVGRLARFALLGAGLALAGCQTDGTGVASGSSRSNQALAFESIDGPPKATFDRLVTKLADQAEQQQVALVSRTQPANYRIRGYVSAHTEKGKTLVNYAWDVFDADKQRVARITGTETIKSAKGGAWASCDDEVIARIAGTTIASLSETLQVGNPNAAASATASAPAAAAPAGPTEAAPPVAEQPAPATAPSSAPVDVGGVPVASASPFGPSAAEAPGLAYASR</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
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        <source>
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    </evidence>
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            <dbReference type="EMBL" id="BAF90024.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4042"/>
    <dbReference type="EnsemblBacteria" id="BAF90040">
        <property type="protein sequence ID" value="BAF90040"/>
        <property type="gene ID" value="AZC_4042"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4042"/>
    <dbReference type="eggNOG" id="COG0499">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025194_2_1_5"/>
    <dbReference type="OMA" id="NKYGCRE"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="238"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="204"/>
            <end position="206"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="267"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="346"/>
            <end position="348"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="477" mass="52526" checksum="719AD864716A7EFE" modified="2007-12-04" version="1">MPRRLEAPTGRADMTDYVVKDINLADWGRKELDIAETEMPGLMATRAEYGPSQPLKGARIAGSLHMTIQTGVLIETLKALGADVRWASCNIYSTQDHAAAAIAAAGTPVFAVKGETLEEYWEYTHRIFEWADGGTPNMILDDGGDATLLVHLGLRAENGDTAFLDGATNEEEEVLFAAIKRRLKHKHGWYTQLAKNIRGVTEETTTGVHRLYEMQKKGTLLWPAINVNDSVTKSKFDNLYGCRESLVDGIRRGTDVMMAGKVAMIAGFGDVGKGSAASLRNAGCRVLVSEIDPICALQAAMEGYEVTTMEDAAPRADIFVTATGNLDVITVDHMRAMKDRAIVCNIGHFDSEIQVAGLKNFKWHNVKPQVDEVEFPDKKRIILLSEGRLVNLGNATGHPSFVMSASFTNQTLAQIELWTKPGHYEKKVYTLPKHLDEKVAALHLEKIGVKLTKLSKVQADYIGVPGEGPFKPEHYRY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILN3</accession>
    <name>LEUD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="1">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Alpha-IPM isomerase</fullName>
            <shortName evidence="1">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuD</name>
        <name type="ordered locus">AZC_4057</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172577.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ILN3"/>
    <dbReference type="SMR" id="A8ILN3"/>
    <dbReference type="STRING" id="438753.AZC_4057"/>
    <dbReference type="EnsemblBacteria" id="BAF90055">
        <property type="protein sequence ID" value="BAF90055"/>
        <property type="gene ID" value="AZC_4057"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4057"/>
    <dbReference type="eggNOG" id="COG0066">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_081378_0_3_5"/>
    <dbReference type="OMA" id="AFTTHTG"/>
    <dbReference type="OrthoDB" id="1384217at2"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword id="KW-0432">Leucine biosynthesis</keyword>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000072956" description="3-isopropylmalate dehydratase small subunit">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <sequence length="201" mass="22318" checksum="4EF4013B74321780" modified="2007-12-04" version="1">MEKFTTLEGVAAPLKIVNVDTDMIIPKQYLKTIKRTGLGTGLFSEMRYKEDGSDNPDFVLNQPAYRNAKIIVAGDNFGCGSSREHAPWALLDFGIRCVISTSFADIFYNNCFKNGILPIVVSKDDLDKLFDDADRGANATLTIDLAAQEIRGPDGGTVKFEIDPFRKRCLLEGLDDIGLTLEKGTQIDTYEGEKKTEQPWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM48</accession>
    <name>A8IM48_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutathione-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3">1.11.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0486</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a hydroperoxide + 2 glutathione = an alcohol + glutathione disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62632"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="EC" id="1.11.1.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.27" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169017.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0486"/>
    <dbReference type="EnsemblBacteria" id="BAF86484">
        <property type="protein sequence ID" value="BAF86484"/>
        <property type="gene ID" value="AZC_0486"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0486"/>
    <dbReference type="eggNOG" id="COG0678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072440_1_2_5"/>
    <dbReference type="OMA" id="GYINHPK"/>
    <dbReference type="OrthoDB" id="892697at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PTHR10430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="161" mass="17053" checksum="1D3238649A92B00E" modified="2007-12-04" version="1">MPIQVGDSLPNVTFRVSTSDGPVPKTTDEVFKGKRVVLFAVPGAFTPTCHKNHLPGYVSRAEEIKAKNIDTIAVVSVNDPFVMGAWEQASGADGKVLFLSDGNGDFAKALDLFFDGSAVGLGLRSKRYSMLVEDGVVKVLNVEDVPSKADASSAQALLAQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMJ0</accession>
    <name>A8IMJ0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-dehydro-3-deoxy-phosphogluconate aldolase</fullName>
            <ecNumber evidence="3">4.1.2.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0561</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:17089"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:57569"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.14"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KHG/KDPG aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.14" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169092.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0561"/>
    <dbReference type="EnsemblBacteria" id="BAF86559">
        <property type="protein sequence ID" value="BAF86559"/>
        <property type="gene ID" value="AZC_0561"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0561"/>
    <dbReference type="eggNOG" id="COG0800">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077795_1_1_5"/>
    <dbReference type="OMA" id="FFPAEYC"/>
    <dbReference type="OrthoDB" id="1497385at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008675">
        <property type="term" value="F:2-dehydro-3-deoxy-phosphogluconate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00452">
        <property type="entry name" value="KDPG_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000887">
        <property type="entry name" value="Aldlse_KDPG_KHG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031337">
        <property type="entry name" value="KDPG/KHG_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031338">
        <property type="entry name" value="KDPG/KHG_AS_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30246">
        <property type="entry name" value="PTHR30246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01081">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01182">
        <property type="entry name" value="eda"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00159">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00160">
        <property type="entry name" value="ALDOLASE_KDPG_KHG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="215" mass="21714" checksum="91F90E03A009BF28" modified="2007-12-04" version="1">MSQSNPLPLIARAPVIPVVVIERLEDAVPLARALVEGGLPLIEVTLRTPVALRAMSVIAAEVEGAIVGAGTVTDRSQIEAVVEAGATYIVTPGTTPALAQALAEAPVPVLPGCATASEAMALDALGFKVLKFFPAEPSGGAPFLKGLAGPLPALRFCPTGGIGPSNAPDYLALPNVVAVGGSWVVPGDAIKAGNFDKVRELSAAAAKLPRAAKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMN9</accession>
    <name>A8IMN9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative outer membrane lipoprotein</fullName>
        </submittedName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <comment type="similarity">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="8 9" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <topology evidence="1">Peripheral membrane protein</topology>
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    <comment type="similarity">
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    </dbReference>
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        <property type="entry name" value="oligo_HPY"/>
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    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="5"/>
            <end position="256"/>
        </location>
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    <feature type="binding site" evidence="6">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="340" mass="36886" checksum="B79976FE49611B67" modified="2007-12-04" version="1">MAPLLQIRNLTVAFDTPAGVVHAVNDVSYDLEEGETLGIVGESGSGKSVHVLAMTGLIARPPGRIVAGSVLFEGRDLLTMPERELRDLRGGRIGFVFQDPMTSLNPVLTVERQLVELLVRHQPLSKAQARKRAIELLELVRIPDAEKRIGQYPHQFSGGMRQRVMIAIGVACNPRLLIADEATTALDVTVQAQILDMMRDLKRAFGTTIIWITHDMGVVAGLADTVQVMYAGRILERGPVDAVFDDPRNAYTWGLLQSLPTAERRAEGRLHQIPGSPPNLAAPQVGDPFAPRNAFATPRCFKEMPPLKQVEHGAPGHLAAAWYDLPAALKAKGLAMGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8INQ9</accession>
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        <submittedName>
            <fullName evidence="8">Peptide ABC transporter ATP-binding protein</fullName>
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    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172301.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3778"/>
    <dbReference type="EnsemblBacteria" id="BAF89776">
        <property type="protein sequence ID" value="BAF89776"/>
        <property type="gene ID" value="AZC_3778"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3778"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_5"/>
    <dbReference type="OMA" id="AAVEHMS"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="10"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="306" mass="34503" checksum="E4091C5E24D459BB" modified="2007-12-04" version="1">MSTHPCTPLLDVKDLRKTYTSRQGLFGRATSEVRAIDGVSFHIGHKEILGLVGESGSGKSTTGRVVLRLEEPTGGEVFFEGNRITDLPPLELKPYRRQMQVVFQDPYAALNPRMTVGDFVTEPLIVHHLADNRTERQDRVAELFRQVGLDPAFMARYPHEFSGGQRQRVNIARAIAMRPRLIVADEPITALDVSIQAQIVNLFQDLQQELGMAYLFIAHDLSMVRYLCHRVAVMLRGRIVEMAPTEAIFTDPLHPYTRSLLSAIPVPKPAIERQRHPIPFDYEREKPAPDATLQEVAPDHFVLISP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A8INV5</accession>
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        <submittedName>
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    <gene>
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    <organism evidence="3 4">
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
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                <person name="Lee KB."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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    </comment>
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        <property type="protein sequence ID" value="BAF86631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169164.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0633"/>
    <dbReference type="EnsemblBacteria" id="BAF86631">
        <property type="protein sequence ID" value="BAF86631"/>
        <property type="gene ID" value="AZC_0633"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0633"/>
    <dbReference type="eggNOG" id="COG1261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_131516_1_0_5"/>
    <dbReference type="OMA" id="ARNMDSG"/>
    <dbReference type="OrthoDB" id="1885942at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017585">
        <property type="entry name" value="Flag_basal_body_FlgA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039246">
        <property type="entry name" value="Flagellar_FlgA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36307">
        <property type="entry name" value="PTHR36307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13144">
        <property type="entry name" value="ChapFlgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03170">
        <property type="entry name" value="flgA_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="1" id="KW-0574">Periplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5005121973" description="Flagella basal body P-ring formation protein FlgA" evidence="1">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="ChapFlgA" evidence="2">
        <location>
            <begin position="68"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="190" mass="19005" checksum="E2E2547DF7E8F8FA" modified="2007-12-04" version="1">MRTILAALAVLAGLATMPAAAQSTSGLSISSRVAAAEAAEAAARSKAPAPSAQAPAIPEPASIVLPVPAVAIYPGDTISDSMLVDRAYSVSPSDRVAVATSRQALIGKVARRGLQAGTPIPVNAYADPQVVSRGHLAPVVLQEGGLTISGFAMAMEDGSVGKIVRLKNLDSGLIIAGTVQSDGSVRVSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPL7</accession>
    <name>A8IPL7_AZOC5</name>
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        <recommendedName>
            <fullName evidence="4">Flagellar hook-associated protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">flgK</name>
        <name evidence="8" type="ordered locus">AZC_0648</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169179.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0648"/>
    <dbReference type="EnsemblBacteria" id="BAF86646">
        <property type="protein sequence ID" value="BAF86646"/>
        <property type="gene ID" value="AZC_0648"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0648"/>
    <dbReference type="eggNOG" id="COG1256">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012762_3_2_5"/>
    <dbReference type="OMA" id="DQYEVAQ"/>
    <dbReference type="OrthoDB" id="1815809at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002371">
        <property type="entry name" value="FlgK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30033">
        <property type="entry name" value="PTHR30033"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02492">
        <property type="entry name" value="flgK_ends"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="439"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="485" mass="49862" checksum="97D1FB0CC10B36C3" modified="2007-12-04" version="1">MSLTSAFSTARNSLLNTATQLSTSAKNIENASNTSYSRKNANLVSGDAGNTSVVVARAGDAALFLKMLDATSNSSKYAALLTGLTTLQSTIGDTETDTSVAARLSTFQTALSSYANAPDNDTLGQAAITAAENLATALNSSTRTVQSVRAEADANIANSVSKVNDLLSQFKIANDAVIAGTVKGDDISDALDARDAVLSKLSEEMGVTTVLGQNNDMKLYTDGGATLFDQSPRSVTFVPSATFDGTTVGNAVYVDGVAVTGASSVMPLKSGAIAGYAEMRDVTTVTYQDQLDEVARGLISAFQETDQSGGGGAAKSGLFTNGIDTTVAGGLTRNLAATITVNTAAVVSKGGSVSTLRDGGMNGAAYAYNTTNAASFGTRLAALQTAIKAQQTFSSTTQLTSGVSLQTFASSSVSWLEGLRTSTTNKSETQKTLLSQASTAVSNASGVNTDQEYATQLQLEKSYQASSKILSAVQSMYDALFSAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPM0</accession>
    <name>A8IPM0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flagellar FlaF protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">flaF</name>
        <name evidence="1" type="ordered locus">AZC_0650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <dbReference type="STRING" id="438753.AZC_0650"/>
    <dbReference type="EnsemblBacteria" id="BAF86648">
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    <keyword evidence="1" id="KW-0282">Flagellum</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="115" mass="13020" checksum="23ABE3AE26900DE0" modified="2007-12-04" version="1">MYKFSYAEILEDSSTESRARERDAFDRALELLVSAESAGLDTPECRAAMLFLQRLWGLLIRDLTDANNELAPELRADLVSIGLWNIREADRVLEQSSSNFSGLININRTIRDGLQ</sequence>
</entry>
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        <name evidence="9" type="ordered locus">AZC_0660</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
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        <property type="entry name" value="HAMP_dom"/>
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        <property type="entry name" value="MCPsignal_dom"/>
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        <property type="entry name" value="T_SNARE_dom"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="218"/>
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    </feature>
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        <location>
            <begin position="220"/>
            <end position="273"/>
        </location>
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    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="321"/>
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        <location>
            <begin position="466"/>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="570" mass="60089" checksum="533B37DE16063881" modified="2007-12-04" version="1">MIRSQGGTERKTKMKIAGKIYSIVGILGLTTLIVCVMGLSALNELNNTSDRLDATAQRAFVAEKLNGAITAVVMESRGIYAAPDIAAAKPFAAGLRKQLDNVDQLAAQLKRLSGNTDAQAVDAVLSDLAKFREFRVETARLGESVSPQAANVQGNNDANRANRRALQASVDRLTDQIRNELEPLRARIDGLQNQTWWRLVILTGVGLLIGGSIAIWIGTRTMSRPLRRASETLRRLASGELDVAVEAQRSKDEIGDLWQSTKQLLEELRQADRLRIEQRELAVRAESDKRAAMHSLADEFDREVSGVVRTVAEAVSTLERNAATMSASADQTSRQSTVVAAAAEEATSNVQTAASAAEELAASVREIGTQVSTAAKIAEEATGQAAKTADVARGLSASATRIGQVVQLITDIASQTNLLALNATIEAARAGDAGKGFAVVASEVKSLAEQTSKATDEISAQVSAVQGATDEVVRAIEGISDTIRKIDDISSAIANAIDQQGAATGEIAQNVSQAAQGTQEVSSSITGVSAAAQATGRVSTDIVHAATDLSAQASRLRSQVDTFVARVRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0713"/>
    <dbReference type="EnsemblBacteria" id="BAF86711">
        <property type="protein sequence ID" value="BAF86711"/>
        <property type="gene ID" value="AZC_0713"/>
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    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="2">
        <location>
            <begin position="742"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="951"/>
            <end position="978"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1015" mass="108575" checksum="D5E539B74072A7FC" modified="2007-12-04" version="1">MSRVFTIPSSAPFLKTLAHAMLDGHLVPGFAPRGDPLALASATIYLPTRRAGRLFADAMLEAVGGEAVLLPRIVPLGDVDEDALAFSEEAALLAPPQAVAGVHRRIALAGLVARWRDALAEGEGQAMVAAGPAATMALADELGRLFDQMTTAGIAWSRLDDLVPEEHDAYFEISLQFLRIARQAWGAHLEEMGLVDPAERRDALVGAEERRLAALGAGAGPVIAAGSTGSLPTTARLLKAIASLPQGAVVLPGLDLHMEETAFQLLTAEATSAPDHPQFGLAKLLGTLGLERRDVTALATPAPWGREALLSEALRQSETAEQWASLSERLPDAKRAQALAEVRVVKALDPREEALAVALELRDALTKPDMRAALVTHDRDLARRVAAELERFGIAIDDSAGVPLAETQPARLARLVAKTVAEGCAPVPLFALLSQPGLSLDLAPEILAEAVAALELIALRGPRPRSGAAGLAAAVAAFDAAKVHERDPRRRVGEDRQALAADLVARLVPALEPLSALAEAGKVPLADLVAAHIATIESLTAPLDPDANDPAWASLAEALIDIRDGAPAGPAMTLAAYADAISALLADRVVRPRQRGEERIRILGPLEARLVAVDRVVLGGLVEGSWPPETRTDPWLSRPMRAELGLDQPERRIGLAAHDFAQAFGAREVVLTYPDKVGGTQSVPSRFLQRLSTVAGEDLWQAAIARGEAWRQAAARLDDGPRVPRAAQPAPKPPRELRPKKLSVTEVETFLRDPYSIFARHVLALQPLEALDAAPGGAERGSALHDALGAFAKDYPEDLPPDAHAQLLAYGRRAFEKLEVFPAEHAIWWARFERVAAFVVEFERERRASLKRVVAETGGGLPIRLLHSDFQLTGRADRIEIRTDGELNILDYKTGTAPSAKQGATFSPQLPLEAAMAVRGGFRDVPAANVANFLYVELKGGAVAGREKPGVDEKSSAMAMAEDALERLRELLLAFENEEQGYRALAAPQWRGRFGPYDHLARVREWALGAEEGGE</sequence>
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        <name evidence="2" type="ordered locus">AZC_0753</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0753"/>
    <dbReference type="EnsemblBacteria" id="BAF86751">
        <property type="protein sequence ID" value="BAF86751"/>
        <property type="gene ID" value="AZC_0753"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0753"/>
    <dbReference type="eggNOG" id="COG5342">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1068116_0_0_5"/>
    <dbReference type="OMA" id="WIKNAAE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="Gene3D" id="2.60.40.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038696">
        <property type="entry name" value="IalB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010642">
        <property type="entry name" value="Invasion_prot_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06776">
        <property type="entry name" value="IalB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="260" mass="27557" checksum="4E826FAC419EF90B" modified="2007-12-04" version="1">MSAPDPSDAGAAAGTPHPGTGSHQKPVTGVLFRRLLREINQKGNVVCAIFSAASPITEAPLPATDFMFASMRADRIPRSGDAMAHHRASFNRARLTLMAAALMACAAGTASAQGQGSSKAVAQFGDWSVYVSTSAPKVCYAISQPKDRQPGGLKRDPAYFFISTRPGENVKNEVSFTMGFPLKEGSEAKVTVGGTTFELYTKSEGAWVRNVADEGRLVDTLRKGRDAIVVSSSSRGNPTTDKYSLNGIGQALDRVAQECR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-10-01" modified="2022-05-25" version="109" xmlns="http://uniprot.org/uniprot">
    <accession>Q07755</accession>
    <accession>A8IP06</accession>
    <name>NODC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>N-acetylglucosaminyltransferase</fullName>
            <ecNumber>2.4.1.-</ecNumber>
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        <alternativeName>
            <fullName>Nodulation protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">nodC</name>
        <name type="ordered locus">AZC_3816</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1989" name="Mol. Gen. Genet." volume="219" first="289" last="298">
            <title>Common nodABC genes in Nod locus 1 of Azorhizobium caulinodans: nucleotide sequence and plant-inducible expression.</title>
            <authorList>
                <person name="Goethals K."/>
                <person name="Gao M."/>
                <person name="Tomekpe K."/>
                <person name="van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
            <dbReference type="PubMed" id="2615763"/>
            <dbReference type="DOI" id="10.1007/BF00261190"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="1994" name="Proc. Natl. Acad. Sci. U.S.A." volume="91" first="2669" last="2673">
            <title>The NodC protein of Azorhizobium caulinodans is an N-acetylglucosaminyltransferase.</title>
            <authorList>
                <person name="Geremia R.A."/>
                <person name="Mergaert P."/>
                <person name="Geelen D."/>
                <person name="van Montagu M."/>
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            <dbReference type="DOI" id="10.1073/pnas.91.7.2669"/>
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        <text evidence="1">Involved in the synthesis of Nod factor, a sulfated N-acyl-beta-1,4-tetrasaccharide of N-acetylglucosamine which initiates a series of events in the host plant species leading eventually to nodulation.</text>
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        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
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        <text evidence="2">Belongs to the NodC/HAS family.</text>
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        <property type="family name" value="Glycosyltransferase Family 2"/>
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    <dbReference type="EnsemblBacteria" id="BAF89814">
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        <property type="gene ID" value="AZC_3816"/>
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    <dbReference type="KEGG" id="azc:AZC_3816"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0328">Glycosyltransferase</keyword>
    <keyword id="KW-0472">Membrane</keyword>
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            <begin position="1"/>
            <end position="397"/>
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        <original>KR</original>
        <variation>T</variation>
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            <begin position="119"/>
            <end position="120"/>
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        <original>G</original>
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    <feature type="sequence conflict" description="In Ref. 1; AAB51164." evidence="2" ref="1">
        <original>LA</original>
        <variation>S</variation>
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            <begin position="270"/>
            <end position="271"/>
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    </evidence>
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    <sequence length="397" mass="43834" checksum="7D18EDCAF864D7F8" modified="2008-02-26" version="2">MSVVDVIGLLATAAYVTLASAYKVVQFINVSSVTDVAGLESDALPLTPRVDVIVPTFNENSSTLLECVASICAQDYRGPITIVVVDDGSTNKTSFHAVCDKYASDERFIFVELDQNKGKRAAQMEAIRRTDGDLILNVDSDTVIDKDVVTKLASSMRAPNVGGVMGQLVAKNRERSWLTRLIDMEYWLACNEERIAQSRFGSVMCCCGPCAMYRRSAITPLLAEYEHQTFLGRPSNFGEDRHLTILMLKAGFRTGYVPGAVARTLVPDGLAPYLRQQLRWARSTYRDTALALRIKKNLSKYITFEICAQNLGTALLLVMTMISLSLTTSGSQTPVIILGVVVGMSIIRCCSVALIAKDFRFLYFIVHSALNVLILTPLKLYALLTIRDSRWLSRESS</sequence>
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        <name evidence="2" type="ordered locus">AZC_1019</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1019"/>
    <dbReference type="EnsemblBacteria" id="BAF87017">
        <property type="protein sequence ID" value="BAF87017"/>
        <property type="gene ID" value="AZC_1019"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1019"/>
    <dbReference type="HOGENOM" id="CLU_2115950_0_0_5"/>
    <dbReference type="OMA" id="ACEFFAG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723851" evidence="1">
        <location>
            <begin position="23"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="114" mass="11610" checksum="34C0487CFFA0AD2C" modified="2007-12-04" version="1">MKRMVVAFLALGVAGAVVPAFAQQPPQPANLQLQVDKVSTDPAGAFINIRVKNVGTVAISQIDVGCQFLAKGKVIGTSSTTLFASVPGVTGIGQVRLMGATNATDARCGILKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQY6</accession>
    <name>A8HQY6_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87074.1"/>
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    </evidence>
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        <source>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ros/MucR family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="AZC_1086"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1086"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="180" mass="20406" checksum="0BBB86BE5B5B65DB" modified="2007-12-04" version="1">MSGARRIAALSQRYPRVWRKLEFSRRGQHAVVKFVSKLEERPMSEATESTTYIELAADIVSAYVSNNSVAAADLPNLINEVHAALQRVSKGESEPAPEPLKPAVPVKKSVTPDFIVCLEDGKKFKSLKRHLRTQYNMSPEQYREKWALPPDYPMVAPNYAAARSELAKQMGLGQQRRRRR</sequence>
</entry>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169705.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1174"/>
    <dbReference type="EnsemblBacteria" id="BAF87172">
        <property type="protein sequence ID" value="BAF87172"/>
        <property type="gene ID" value="AZC_1174"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1174"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_14_3_5"/>
    <dbReference type="OMA" id="MQVHHIH"/>
    <dbReference type="OrthoDB" id="1885467at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="25"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="6">
        <location>
            <begin position="290"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="374" mass="40832" checksum="8787B015FD7AD513" modified="2007-12-04" version="1">MDARTIRPDPRLASPAEVPPTWDPERDDVLVVRQVRQETADVKTFVLAPATPARFRYLPGQFITLDLDIDGVRLNRCYTLSSSPTRPDTVAITVKRVPGGPVSNFLHDHLREGSVLRAVGPMGDFTCAQHEAPKYLFLSGGSGITPVMSMARAHADLATGADIAFLHSARTPADIIFRAELELMARTTPTFRFAAICEADAPFEPWHGLRGRLSLAHLEAAVPDFRAREVFVCGPAPYMAAVREMLRAAGFDMARHHEESFDFATLATAEPEVAAEVIAAEGETSAARVHRVEFRKSGRVIECPEDMNVLEAARRAGMRLPSSCTKGLCGTCKCKLAEGTVEMKHGGGIRQREIDAGMVLICCARPTSDLVIER</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRQ8</accession>
    <name>Y4080_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative hydro-lyase AZC_4080</fullName>
            <ecNumber evidence="1">4.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_4080</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-glutamate cyclase family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HRQ8"/>
    <dbReference type="SMR" id="A8HRQ8"/>
    <dbReference type="STRING" id="438753.AZC_4080"/>
    <dbReference type="EnsemblBacteria" id="BAF90078">
        <property type="protein sequence ID" value="BAF90078"/>
        <property type="gene ID" value="AZC_4080"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4080"/>
    <dbReference type="eggNOG" id="COG4336">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059759_0_0_5"/>
    <dbReference type="OMA" id="NVPMYKT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01830">
        <property type="entry name" value="Hydro_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009906">
        <property type="entry name" value="D-Glu_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038021">
        <property type="entry name" value="Putative_hydro-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016938">
        <property type="entry name" value="UPF0317"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07286">
        <property type="entry name" value="DUF1445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029755">
        <property type="entry name" value="UCP029755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160920">
        <property type="entry name" value="SSF160920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0456">Lyase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000073688" description="Putative hydro-lyase AZC_4080">
        <location>
            <begin position="1"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01830"/>
        </source>
    </evidence>
    <sequence length="272" mass="28572" checksum="8C33FC34DC87CCC8" modified="2007-12-04" version="1">MTAHASIATPGGISLATGRDVRLASRSGALTGSTAGFAPGFVQANLAILPAKLAFDFLRFCQRNPKPCPVIGVSEPGDPTLSSIGLDLDIRTDVPGYCVYKDGVLVDEPADLKAYWREDLVTFAIGCSLSFEEALMAADIPLRHVEKGVKVPMFRTNIACVPAGPFAGPMVVSMRPMTPANAIRAVQITSRFPSVHGAPIHIGLPEAIGIKDLSKPDYGDAVEILEGEIPVFWACGVTPQSVISAAKIEYALAHGPGMMLCTDLKNSALATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSC6</accession>
    <name>A8HSC6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="6">4.1.2.50</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Queuosine biosynthesis protein QueD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_4167</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.50" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4167"/>
    <dbReference type="EnsemblBacteria" id="BAF90165">
        <property type="protein sequence ID" value="BAF90165"/>
        <property type="gene ID" value="AZC_4167"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4167"/>
    <dbReference type="eggNOG" id="COG0720">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111016_6_3_5"/>
    <dbReference type="OMA" id="ESHVAWA"/>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF90165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="139" mass="14903" checksum="3BEEB59D2AEDDA9C" modified="2007-12-04" version="1">MSSPASLFAVEVRDHIMIAHSFKGDLFGPAQALHGATFVVDVAFMSERLTEEGVVVDIGRATEALKAVLGPLNYRNLDEVPAFADINSTTEVLAKHIFDAMAEAARTGALGTGGDRLCRLRVTLHESHAARAWFEGPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSI8</accession>
    <name>A8HSI8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative Glu-tRNA amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4187</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172707.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4187"/>
    <dbReference type="EnsemblBacteria" id="BAF90185">
        <property type="protein sequence ID" value="BAF90185"/>
        <property type="gene ID" value="AZC_4187"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4187"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_3_5"/>
    <dbReference type="OMA" id="TLINMID"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="449" mass="45468" checksum="BC248559116B72AC" modified="2007-12-04" version="1">MTAPTLASLAADLAAGRTTSRALVEACLARISDPAGEGTRAFISVAGEQARAAADGQDALRRAGAAPSPFAGIPVAIKDLFDVAGEVTTSGSKVLASNTPATADATAVARLRNAGFVVIGRSNMVEFAYSGLGLNPHYGTPKSPWKRDEGRVPGGSTSGGAVAVADGFAHLALGTDTGGSCRIPAAFCGITGYKPTASRVPQEGCLPLSQSLDSIGPLGRSVACCAAADAILAGAPVTALEPADLSGLRFLVPATVALDALDPEVASAFEAAVARISKAGARIVTAPVPEFAEIAGINAKGGFTAAESYAWHRALLAEKEAEYDPRVSVRIKRGREQEAADYIDILAARRSLIARANARIAPFDALLMPTVAILPPKIADLASDDAAYAKANILSLRNCTLVNMIDGCAISLPIPAPGDAPVGLMVAAAGGMDARLFAVAAGIEAQFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSL2</accession>
    <name>A8HSL2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydrogenases</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4194</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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                <person name="Lee KB."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169351.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0820"/>
    <dbReference type="DNASU" id="5689795"/>
    <dbReference type="EnsemblBacteria" id="BAF86818">
        <property type="protein sequence ID" value="BAF86818"/>
        <property type="gene ID" value="AZC_0820"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0820"/>
    <dbReference type="eggNOG" id="COG0665">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007884_9_0_5"/>
    <dbReference type="OMA" id="WRESSPQ"/>
    <dbReference type="OrthoDB" id="573710at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="4"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="421" mass="44192" checksum="97F8FF6ABC60ED14" modified="2007-12-04" version="1">MSLHIVVIGAGIVGASTALELQRDGHRVTLVEPGQPGGPQAASFGNGAWLSPASVVPMSMPGLWKKVPGYLMDPLGPLTIRWTALPALAPWLLRFIAAGATVPKVEATARALKALLSDAPERHTALAAEAGLADLVERKGLLYAYPDRAAFEAEALAWRLRRDNGIVWRELDGPALKAFEPTLHPRYGFGALVEAGAHCVDPGAYVAGLVAFAESRGLTRIEAAATGFDIVGGRLQAVRTAKGSVPCDRAVIAAGIHSRALAAEAGDKVSLASERGYHVVVATPESGPHLPVMPSDGKMANTPTRAGLRASGQVELAAVAAAPNWKRADVLLDHLLNTYPGLPRQVPEARLSRWLGHRPSTPDGVPVIGQASACTDIVHAFGHGHVGLASGPITGRLVADIIAGRPPERDIRPYAAARFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="50" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU14</accession>
    <name>A8HU14_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169426.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0895"/>
    <dbReference type="EnsemblBacteria" id="BAF86893">
        <property type="protein sequence ID" value="BAF86893"/>
        <property type="gene ID" value="AZC_0895"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0895"/>
    <dbReference type="eggNOG" id="ENOG5033ZF5">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_115294_0_0_5"/>
    <dbReference type="OMA" id="FAFTCFD"/>
    <dbReference type="OrthoDB" id="1886753at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723049" evidence="2">
        <location>
            <begin position="22"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="155" mass="16482" checksum="1F3D16F829F51686" modified="2007-12-04" version="1">MRSILLAAAAFVFAGAGTASAQSLSPEQAKAFVVGRSFAFTCFEGTTGAGRVFPDGSVAGTLTLRSQGIARYVRLPPNTLRVRGENVCGFVEGMTFEPCFTVVKTSETTFRGTLAGVDTMWCEFVREGAERPRVASRRKPKPDTSSAVTLESSAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-04-05" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV62</accession>
    <name>COWN_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N(2)-fixation sustaining protein CowN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">CO weal-nitrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cowN</name>
        <name type="ordered locus">AZC_4276</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CowN family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HV62"/>
    <dbReference type="STRING" id="438753.AZC_4276"/>
    <dbReference type="EnsemblBacteria" id="BAF90274">
        <property type="protein sequence ID" value="BAF90274"/>
        <property type="gene ID" value="AZC_4276"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4276"/>
    <dbReference type="eggNOG" id="ENOG5032SZ8">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_149349_0_0_5"/>
    <dbReference type="OMA" id="IDCDGNA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02117">
        <property type="entry name" value="CowN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024899">
        <property type="entry name" value="CowN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0535">Nitrogen fixation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000407250" description="N(2)-fixation sustaining protein CowN">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02117"/>
        </source>
    </evidence>
    <sequence length="122" mass="14006" checksum="FEF2B488651E0BB6" modified="2007-12-04" version="1">MRASPTPWLSRAEPYCQRESPMNLLTTTPAGDRYVTFNGIDFEGNMARVLAHLRRYIDDPRTGNAFWDRFKARLAAAESGGNAFQDKLLLLHSHVYYMGDLFEDQEDEAALADLRKLEEECF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8HW58</accession>
    <name>A8HW58_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycerol-3-phosphate ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172915.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4395"/>
    <dbReference type="EnsemblBacteria" id="BAF90393">
        <property type="protein sequence ID" value="BAF90393"/>
        <property type="gene ID" value="AZC_4395"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4395"/>
    <dbReference type="eggNOG" id="COG1175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_0_2_5"/>
    <dbReference type="OMA" id="LWYSVQS"/>
    <dbReference type="OrthoDB" id="1688736at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="72"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="294" mass="31839" checksum="400584DB75AE941B" modified="2007-12-04" version="1">MQAKRATFPNRLLPYLLLAPQLAVTFVFFIWPALEALTGSVFTEDAFGLSKQFVGLENFAALFQDSAYLEAVGVTFLFSGAVATLSLGLGLLLALAAEKTGKLAGLYRTLLIWPYAVAPAVAAVMFWFMFDPSVGIAARGLKALGITWNHFLDGRQALLLVILAATWKQVSYNLLFFYAGLRAIPRPLIEAAAIDGAGPFRRFTAIVFPLLAPTTFFLLVVNVTYAFFDTFGVIHATTGGGPGRATTTLVYKVFKDGFEGLDLGASSAQSVVLLAIVAGLTVIQFRHIERKVHY</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWM3</accession>
    <name>RL20_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rplT</name>
        <name type="ordered locus">AZC_4448</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172967.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HWM3"/>
    <dbReference type="SMR" id="A8HWM3"/>
    <dbReference type="STRING" id="438753.AZC_4448"/>
    <dbReference type="PRIDE" id="A8HWM3"/>
    <dbReference type="EnsemblBacteria" id="BAF90446">
        <property type="protein sequence ID" value="BAF90446"/>
        <property type="gene ID" value="AZC_4448"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4448"/>
    <dbReference type="eggNOG" id="COG0292">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_123265_0_1_5"/>
    <dbReference type="OMA" id="GRRKNVW"/>
    <dbReference type="OrthoDB" id="1932144at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <feature type="chain" id="PRO_1000072180" description="50S ribosomal protein L20">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <sequence length="119" mass="13457" checksum="F0E0F94F7A5B0252" modified="2007-12-04" version="1">MARVKRGVTSHAKHKKVFKAAKGFYGRRKNTIRAAKSAVERSMQYNYRDRKVKKRTFRALWIQRINAGVRELGMTYGRFIDGLGKAGIEVDRKVLSDIAVHEPETLKALVEKAQAALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX16</accession>
    <name>A8HX16_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1451</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1589"/>
    <dbReference type="EnsemblBacteria" id="BAF87587">
        <property type="protein sequence ID" value="BAF87587"/>
        <property type="gene ID" value="AZC_1589"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1589"/>
    <dbReference type="eggNOG" id="COG0414">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047148_0_0_5"/>
    <dbReference type="OMA" id="CNHKLEP"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="159"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="196"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="289" mass="30730" checksum="1DC209B1475C8D16" modified="2007-12-04" version="1">MGRQRMAEAGKAPKIVGTVAELRSAVADYRRAGETLGFVPTMGALHEGHIALVKQAQTLADRVVVSIFVNPTQFAPNEDFSRYPRTFDADVDKLAQAGCDLVYAPGREDMYPAGFSTGISIAGPAQGLESDFRPHFFSGVAIVVAKLLLQTAADVAVFGEKDYQQLRVVTQMARDLDLPVRIVPGPTVRESDGLALSSRNRYLTPEERTVAPVIHRALTTAAIAIKAGAVPDAAAAEAEATIARAGLKVDYVAARNAETLAPLASPDEPVRLLAAAWLGTTRLIDNIGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYZ4</accession>
    <name>A8HYZ4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_4517</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173036.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4517"/>
    <dbReference type="EnsemblBacteria" id="BAF90515">
        <property type="protein sequence ID" value="BAF90515"/>
        <property type="gene ID" value="AZC_4517"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4517"/>
    <dbReference type="eggNOG" id="COG1741">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045717_1_1_5"/>
    <dbReference type="OMA" id="RPHPHIN"/>
    <dbReference type="OrthoDB" id="833478at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008778">
        <property type="entry name" value="Pirin_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13903">
        <property type="entry name" value="PTHR13903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05726">
        <property type="entry name" value="Pirin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="35"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C" evidence="4">
        <location>
            <begin position="193"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="305" mass="33567" checksum="076615E61C6BB6BC" modified="2007-12-04" version="1">MSWMPSSDPVLGDPHSCDKLDLVIVPRVRDLGDGFAVRRALPHGKRQMVGPFIFFDQMGPVQFLPGHGLDVRPHPHIGLATVTYLFDGRILHKDSEGNALEITPGAMNLMTAGRGIAHSERSPLEARTGTQTMAGIQSWIALPAAQEEIDPSFQHFSASTLPTVEDCGISARIIAGSAFGVRSPVRTASEWLYAEVCLDAAAQIPLDPDTEERGVYVAEGEVEVAGDVFEGPRLLIFRPGDRITIRATRNSRLMLLGGTALEGPRYIWWNFVSSRKERIEQAKEDWKQGRFATVPDESEFIPLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZH6</accession>
    <name>A8HZH6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4584</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="EMBL" id="BAF90610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="317" mass="33373" checksum="F1B5CBD122934C0F" modified="2007-12-04" version="1">MAETPPTKAKAAPKAAPKPKVPPPTPIVPRATVAGRALVAVVAIMTFLAAITVGAVMAVRSTAEVWRADVTREVTIQIRAGDKAVTDAQVKTAVDLARQTPGITEAHVLTEPETGRLLEPWLGSGLDYSDLPVPRIVVLRLDTSSPPDLARLRRTLTDRIPTAALDDHRTWSRRLGAMAEGVMFTGFGLLALVGAATVLSVVFATRAAVATNRAVVEVLHFVGARDGFIAAQFQRHFLKVGTQGGLLGGLSAAALFGGLMSLPRLGIGADPESPGILSWFDPGWLGFAGMAVVVVLIALVTALTSRVTVYRTLRTIT</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
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        <property type="protein sequence ID" value="BAF90662.1"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4664"/>
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        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:cellular catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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        <property type="term" value="P:fatty acid metabolic process"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:organic substance catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="3-OHacyl-CoA_DH"/>
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        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
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        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
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        <property type="entry name" value="3HC_DH_C"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="7"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="4">
        <location>
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            <end position="284"/>
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    <feature type="binding site" evidence="3">
        <location>
            <begin position="12"/>
            <end position="17"/>
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        <ligand>
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        <ligand>
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        </ligand>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
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            <dbReference type="PIRSR" id="PIRSR000105-2"/>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
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            <dbReference type="Pfam" id="PF00725"/>
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    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90662.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="293" mass="32027" checksum="FB1913A8F1D48F5A" modified="2007-12-04" version="1">MSLEIKKVGVIGAGQMGNGIAHVCALAGFDVVLNDQDPERVRSGLATINGNMAKQVSKGTVSEDDRQAALKRIATGSALEDLAECDLVIESATEREEVKRKIFSDVCKVLRPDALLASNTSSISITRLGASTDRPERFIGIHFMNPVPLMELVELVRGIATDDDTFESSKAFVTKLHKTYAVAEDFPAFIVNRILLPMINEAIYTLYEGVGSVDAIDRAMKLGANHPMGPLQLADFIGLDTCLAIMQVLHEGLADSKYRPCPLLVKYVEAGWLGRKTQRGFYDYRGEKPVPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="56" xmlns="http://uniprot.org/uniprot">
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        <name evidence="4" type="primary">fhaC</name>
        <name evidence="4" type="ordered locus">AZC_1922</name>
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        <lineage>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170450.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1922"/>
    <dbReference type="EnsemblBacteria" id="BAF87920">
        <property type="protein sequence ID" value="BAF87920"/>
        <property type="gene ID" value="AZC_1922"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1922"/>
    <dbReference type="eggNOG" id="COG2831">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_474738_0_0_5"/>
    <dbReference type="OMA" id="TYFTAPQ"/>
    <dbReference type="OrthoDB" id="956274at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005565">
        <property type="entry name" value="Hemolysn_activator_HlyB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013686">
        <property type="entry name" value="Polypept-transport_assoc_ShlB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08479">
        <property type="entry name" value="POTRA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03865">
        <property type="entry name" value="ShlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724090" evidence="1">
        <location>
            <begin position="29"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_2" evidence="3">
        <location>
            <begin position="88"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="ShlB" evidence="2">
        <location>
            <begin position="365"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="600" mass="62751" checksum="B3CD10CF8CEEA5CB" modified="2007-12-04" version="1">MSAPRSPIMRTGALALGVVLLPATAALAQVIAPVERNLPPVISGQGRLVIGPQDLAGSPDDTPLGVALSGISLIGPKESVAKRAGRGIRIGAVGEIDRAALTQALTPFLGQPLSRKRIADIQAAIAKVYRSAGYPFVSVTLPPQEVTGGVLTLRVVEFRTGSVKVSGAEPGTEAALSGRVRAVPGQRIASDALEEDLAWLNRSPYHTVNGVFAPGDELGLSTLTLEVTPQKPWQVFGGLSNTGTHSTGFDRYFAGFGAALPGLPESYLSYQITGSPNFWSDPAAVGTGPDQPSYYSQAGRLVISTGARQSLEFVPNYVATRQNAQGATFAYDNQTLEIPVYYRTALSNLVPGLYAGDLILGATGKTVSRTSYFSGSDIGGANADLFELIAGWSVSRSDPFGTTSLDLKLIGNPGGVIGGNSAAQWSRYSGGRVTDVTYVYGTGDLNRVTRLPAGFNWVSDLSGTAAGQPLPDTEQLSLGGLYATRGYTLDDGTVDTGLVWRNELRTPTFALLSSLGVAGVTDQVSPYAFLDLAWGRAYGYQGVLGAVPHNDTSLAGLGLGLDYTLNRNLTATLVGGVALTDATYTKAGDFTLQARVYVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2Y9</accession>
    <name>A8I2Y9_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">ABC transporter permease protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1957</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170484.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1957"/>
    <dbReference type="EnsemblBacteria" id="BAF87955">
        <property type="protein sequence ID" value="BAF87955"/>
        <property type="gene ID" value="AZC_1957"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1957"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_1_5"/>
    <dbReference type="OMA" id="WWLVAFP"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="79"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="282" mass="29827" checksum="B97D78DC7D9242F1" modified="2007-12-04" version="1">MSTATLRHAAFVLRGNPLTAIAAFATGLLVLVALFGPVLVPYDPIASDVAHALEAPSAAHWAGTDQLGRDVFSRLVVAARLDLAIAASAVVLSFALGAVIGSICGYAGGRLDRAVGRFVDVLMAFPLFVLAMAMVAALGNRVENIVIATAIINLPFYIRFARAEVNVRRSAGWVEAARACGDSHLSVVLRFLLPNILPAMAVQISLNLGWAILNAAGLSFIGLGVKPPTPEWGIMVAEGARFISTGKWWLVAFPGLALMLCVLCFNLLGDGLRDILDPRMRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3I8</accession>
    <name>A8I3I8_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2028</name>
    </gene>
    <organism evidence="8 9">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Gevers D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    <evidence type="ECO:0000313" key="2">
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        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170351.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1823"/>
    <dbReference type="EnsemblBacteria" id="BAF87821">
        <property type="protein sequence ID" value="BAF87821"/>
        <property type="gene ID" value="AZC_1823"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1823"/>
    <dbReference type="eggNOG" id="COG0589">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049301_5_2_5"/>
    <dbReference type="OMA" id="EICADVP"/>
    <dbReference type="OrthoDB" id="2040681at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="158"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="280" mass="29443" checksum="B8FE5CD3759A03FB" modified="2007-12-04" version="1">MLYNLKNIFTALCCSTEETETSSALAYALSLAQEAGARLTVQASAQKLSLPHTRVSSTIGGLVAAENERLAQLAGKLADDARAAAELGGVAVRTEVPLLPHLELVERFVAEARVHDLTVVDAESSALSPDRALIEAALFQSGRPLLIVPEGHPVFRGRRILVAWDGSARVARAVNEALPLLRAAAMVEVLSIIGEKDLSKAVPGAGIAPHLSAHGVTFELKEIAAPDGDAGEALRLHAVASGADLIVMGAYAHSWLRQITFGGVTQSLLRAAPLPLFLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8I581</accession>
    <name>A8I581_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Mitochondrial processing peptidase-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M16 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170767.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2240"/>
    <dbReference type="MEROPS" id="M16.016"/>
    <dbReference type="EnsemblBacteria" id="BAF88238">
        <property type="protein sequence ID" value="BAF88238"/>
        <property type="gene ID" value="AZC_2240"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2240"/>
    <dbReference type="eggNOG" id="COG0612">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009902_3_0_5"/>
    <dbReference type="OMA" id="IDVVCDM"/>
    <dbReference type="OrthoDB" id="1188251at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="19"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="180"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="426" mass="45133" checksum="0F204E9C62CF3A5B" modified="2007-12-04" version="1">MSATETGVKTTTLPNGITVVSDAMPHLGTASLGIWVGAGARDEGEQEHGISHLLEHMAFKGTRRRSARRIAEEIEQVGGDINAATSVEQTSYNVRVLGEDVGLGMDILSDILTEPAFAPEELAREKNVIVQEIGAVMDTPDDLVFDLFQERAFPGQAVGRSILGTPDTVRSFDPAGLGAYLGRTYRGPRMVVSAAGAVNHDQLVAEAAERLGTIAGETKPEAAPALYAGGSILTPRDLEQVHVVLGLEGRSYKHPQYHAAQVLSNILGGGMSSRLFQDVREERGLCYSIYSFHWSYADTGIFAIYAGTDEGDVGELTNVVIDQLEAAGETITETELARAKAQMKVGLLAALESSGARADQLARQLLAFNRIIPVEEIVAKVEAVTVDAVRQAARDLVAGGRPTLAAIGPGKGLDPAARAVERLAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8I583</accession>
    <name>A8I583_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal-protein-alanine N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2241</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2241"/>
    <dbReference type="EnsemblBacteria" id="BAF88239">
        <property type="protein sequence ID" value="BAF88239"/>
        <property type="gene ID" value="AZC_2241"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2241"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013985_40_1_5"/>
    <dbReference type="OMA" id="AACIPDN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="221" mass="25320" checksum="22FBBE481D02857D" modified="2007-12-04" version="1">MWLFKSVFASDQIPVVHGDGVYLRVPQASDFADWRDLREASRDFLTPWEPVWPADDLTRGSYRRRMRRYARDMMADEAYPLFLFRTHDHALLGGMTLSNVRRGVCQSASLGYWMGAAFAGQGYMGAGVAALLPLAYDVLRLRRIEAACMVRNTPSIRLLERLGFMHEGYARQYLCINGRWEDHLLFARLRTDRAKPREARPDAATQWGVVPGGRAERPLVR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5P5</accession>
    <name>FOLD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="1">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="1">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="1">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="1">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="1" type="primary">folD</name>
        <name type="ordered locus">AZC_2306</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="1"/>
    <dbReference type="EC" id="3.5.4.9" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I5P5"/>
    <dbReference type="SMR" id="A8I5P5"/>
    <dbReference type="STRING" id="438753.AZC_2306"/>
    <dbReference type="EnsemblBacteria" id="BAF88304">
        <property type="protein sequence ID" value="BAF88304"/>
        <property type="gene ID" value="AZC_2306"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2306"/>
    <dbReference type="eggNOG" id="COG0190">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034045_2_1_5"/>
    <dbReference type="OMA" id="HIVGRPM"/>
    <dbReference type="OrthoDB" id="1449514at2"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0486">Methionine biosynthesis</keyword>
    <keyword id="KW-0511">Multifunctional enzyme</keyword>
    <keyword id="KW-0521">NADP</keyword>
    <keyword id="KW-0554">One-carbon metabolism</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0658">Purine biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000318783" description="Bifunctional protein FolD">
        <location>
            <begin position="1"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="167"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <sequence length="290" mass="30300" checksum="762E430F6E1B39CC" modified="2007-12-04" version="1">MIETKPIDGKAFAAGLRARIAEEVAVLVRDHDLKPGLAVVLVGEDPASQVYVRNKAAQTAEAGMASFEYKLPADTAEADLLALVEKLNADPAVNGILVQLPLPAHLDSMKVLAAIDPAKDVDGFHVVNAGRLAVGLDALVPCTPLGCVMLLKHHLGNLSGLNAVVVGRSNIVGKPAAQLLLREDCTVTIAHSRTRDLPGMCRQADILVAAVGRPEMVRGDWIKPGATVIDVGINRVPKADGKTRLVGDVAYEEALGVAGLITPVPGGVGPMTIACLLQNTLTAARRQKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8I641</accession>
    <name>A8I641_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_2360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2360"/>
    <dbReference type="MEROPS" id="C82.003"/>
    <dbReference type="EnsemblBacteria" id="BAF88358">
        <property type="protein sequence ID" value="BAF88358"/>
        <property type="gene ID" value="AZC_2360"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2360"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042399_2_1_5"/>
    <dbReference type="OMA" id="FRMTNED"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YkuD" evidence="4">
        <location>
            <begin position="99"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="228" mass="24865" checksum="9EB2900E60F97117" modified="2007-12-04" version="1">MRRPTIRLHHLRVCGEISAVSCPALSRAWSDRLMMRRSLAAAAVLAVSLGSAVAAPYQSPQPTDFFGFAALFSGAGNVAGTSPFPRHLVAFDAKYQPGSIVVNTAQRRLYFVTAPGQAMEYGVGVGRDGFQWSGVKTVSAKKEWPSWTPPEQMLKRRPDLPRYMPGGIENPLGARAMYLGSSLYRIHGSNEPETIGQAVSSGCIRMTNDDVIDLYNRVKVGATVYVMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6J0</accession>
    <name>A8I6J0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ordered locus">AZC_2414</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2414"/>
    <dbReference type="EnsemblBacteria" id="BAF88412">
        <property type="protein sequence ID" value="BAF88412"/>
        <property type="gene ID" value="AZC_2414"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2414"/>
    <dbReference type="eggNOG" id="COG0026">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011534_0_1_5"/>
    <dbReference type="OMA" id="ITFDHEH"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="108"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="149"/>
            <end position="155"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="179"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="267"/>
            <end position="268"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="364" mass="39019" checksum="8D4CA34994344D50" modified="2007-12-04" version="1">MLKPGSTIGILGGGQLGRMLALAAAPLGLKTHVLCPDADSPAFQVCDAHVCAAYDDFDALDRFAAGVDVVTYEFENVPLATAERLSMHVPVLPGAKALAITQDRLLEKSFVRDLGIGTAPFASVDDLPGLEVAVAAIGLPAVLKTRRFGYDGKGQVTLRPGDDVAGAWEAIGRQPAILEGFVPFVREVSIVAARRADDAFAAFDVTENVHRDHILHRSTVPATLQADAMRDARRIACQIASALDYVGVFAVELFVVANQGVESVLVNEIAPRVHNSGHWTQDGAVTSQFEQHVRAIAGWPLGDARRLGRAEMVNLIGDDVEQWLPLLAEPGTHLHLYGKGEARPGRKMGHVNRLWIDEKAVPGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8I781</accession>
    <name>A8I781_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <sequence length="204" mass="21704" checksum="935154F406552AE9" modified="2007-12-04" version="1">MMHEAIPFSQTALVLVDLQNDFIDPKGAYGRAGQGAAAIAALPDRLAPLADAMRAKGGWIVSTHFTLVPAKGGEPLISPHLKELRPFLAKGDFLPGSWGHQLVDRLGPSDLSVEKIAYSAFYMTRLEWVLRKCDIRRLIVGGIVTNGGVASTVRDAHVRDFDVSVLSDGSAAFSDEVHQTAIAALKPVCTVTTIAEVMGEVGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7P4</accession>
    <name>A8I7P4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2145"/>
    <dbReference type="EnsemblBacteria" id="BAF88143">
        <property type="protein sequence ID" value="BAF88143"/>
        <property type="gene ID" value="AZC_2145"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2145"/>
    <dbReference type="eggNOG" id="ENOG502Z8KY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089980_0_0_5"/>
    <dbReference type="OMA" id="QFDLKYW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="283" mass="31974" checksum="D6FD31CB7787ED7C" modified="2007-12-04" version="1">MPAWLECKGTVMTEQGTITPSQICERLLQKGKAYNIEHNILPSVNAVADRLLARGTELTDAYVELHEKLGSHPSALEVFLDQLLSTAAFWNRERTREARSDRERLQIINAEIAKISASLYSLIEERNDLHNRSSFRSDTYYHPLDLIEKAAAKNYLYHCHIRDSLATLRGRYDLKYWPSIGDCLLVLSRDAATSKVSASDPLTEAATQGKRGSLADFFKTLFVTIEQNKRRNAGFLPDDFRLTDASLASLVTCALDLDPDEVVDSAYVKRLRQRERERVGTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I858</accession>
    <name>A8I858_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2213</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be part of an ABC transporter complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MlaE permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2213"/>
    <dbReference type="EnsemblBacteria" id="BAF88211">
        <property type="protein sequence ID" value="BAF88211"/>
        <property type="gene ID" value="AZC_2213"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2213"/>
    <dbReference type="eggNOG" id="COG0767">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1366">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045686_0_0_5"/>
    <dbReference type="OMA" id="PFWGFAI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="9">
        <location>
            <begin position="62"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="408" mass="44371" checksum="E41A7512C3CAEBEA" modified="2007-12-04" version="1">MLRSRSISTPEGRASMSMGTLVPQATRSTPETRVADASLLDVHAEGDHIKVEGQGAWTSEYADSLEQAVMQVASHYGEAKAVEIDLSRLDRMDTFGALLLERLRRVWQEKGVEPQIVGLNPAYSVLIEEMTRTGREPPPPERKPPGVFERIGREMVVITEDAVSLLNFVGAVVAAFGRVLTRPRSFRFTSMVNQMDRVGFRAMPIIILITFLIGCIIAQQGIFNFRRFGADIYVVDMVGVLVLRELGVLIVSIMIAGRSGSAYTAELGSMRMREEVDALRVMGFDPVEVLVVPRLLALIICLPLLTFVGSMAAMIGGGLVAWFYGGIAPDVFINRLKDAITLAQFEVGMIKAPFMAAIIGVVGCMEGLRVGGSAESLGQHTTASVVKAIFLVIVVDGLFAIFFASIDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2755</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2755"/>
    <dbReference type="EnsemblBacteria" id="BAF88753">
        <property type="protein sequence ID" value="BAF88753"/>
        <property type="gene ID" value="AZC_2755"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2755"/>
    <dbReference type="eggNOG" id="ENOG5032SMK">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090563_0_0_5"/>
    <dbReference type="OMA" id="AFYEILF"/>
    <dbReference type="OrthoDB" id="1688537at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724256" evidence="1">
        <location>
            <begin position="30"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="264" mass="29218" checksum="746A506992AD5CF4" modified="2007-12-04" version="1">MMRIQSLWTRVFATATLVAAVVWPLTAQAQAPMVNLTDPCPIKAENWRGRAFYEILFMFRQPDGGGIGNYFNSLSNKLPKSKDVMDARFRALNAETLKKEFGGDGVFFNGPRRLVANTITGMSWDGCKQRVIAGIPLNLDGVFEVPSLEKFVSGSMPAYKPMVSKRTSSMLFKAGETVYELITPEGAVYTMFSLSLKIDPKNTIENLPTLGKRLTLPAGWQFRSRKLDKDMVLTATADSNPPNTVVLDQLEGNYQYNAGASAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9F4</accession>
    <name>A8I9F4_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
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        <name evidence="3" type="ordered locus">AZC_2783</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171307.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2783"/>
    <dbReference type="EnsemblBacteria" id="BAF88781">
        <property type="protein sequence ID" value="BAF88781"/>
        <property type="gene ID" value="AZC_2783"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2783"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="MTWNESG"/>
    <dbReference type="OrthoDB" id="1591366at2"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003700">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="LysR_subst-bd"/>
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        <property type="entry name" value="SyrM_PBP2"/>
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        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
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    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88781.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="309" mass="34189" checksum="7E2E0278C80B9E7C" modified="2007-12-04" version="1">MRYDLNLLPVFVTLMEERSVTRAAERLGMTQPALSNALARLRVVMRDPLFIRERYGIQPTPLALELAPVLRAALAQIDEVVHGQQAFEPAEAERLMTIAPNSYAEFALIPTVVARLRAVAPGISLRLTPYGSDLSETGVISGTTAMAIGRFVEVQDNLVVQHLMDDGLACVVRADHPDVGDVLTRETYERLRHVNVLPPGRLRAGLFQVLERHGLKRDVAVSVTHFLAVPEMIAVTDYCATLPRLICARLAHDTRLKFVPAPVDLGTFPVDMAWHVRYRHDPAHRWLRTLIAEVAREAAGTAPAPEDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9N2</accession>
    <name>A8I9N2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Membrane bound O-acyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_2811</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the membrane-bound acyltransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171335.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2811"/>
    <dbReference type="EnsemblBacteria" id="BAF88809">
        <property type="protein sequence ID" value="BAF88809"/>
        <property type="gene ID" value="AZC_2811"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2811"/>
    <dbReference type="eggNOG" id="COG1696">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025255_1_3_5"/>
    <dbReference type="OMA" id="CFCWIFF"/>
    <dbReference type="OrthoDB" id="1297594at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042121">
        <property type="term" value="P:alginic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024194">
        <property type="entry name" value="Ac/AlaTfrase_AlgI/DltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028362">
        <property type="entry name" value="AlgI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500217">
        <property type="entry name" value="AlgI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016636">
        <property type="entry name" value="AlgI_DltB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="310"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR016636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="468" mass="52962" checksum="2A1002981EB5A79B" modified="2007-12-04" version="1">MTFASVEFIFYFFPLFLIFYFSSRKLKIRNLVLVLFSLAFYSVGYVPYLFLLLASICVNFIIALRIDERQNASRKTFLILGVTANVLLLGVFKYTDFAVDNLNVLLAPFHLRLPEPDIALPLGISFYSFHAISYLADIYKGRVRANRSLGQFTLYMSMFPQLVAGPIVRYATVARQLGDRRVTWGRFSAGMRLFVIGLAWKVMIADEVAALADGVFDSTTHPTFVEALLGLYAYTVQIYFDFGGYSTMAVGLGVMMGFTLPRNFRLPYAARSVTDFWRRWHMSLSSWLRDYVYITLGGNRRGATRTYVNLWIVFLLCGLWHGASWNFVIWGAWHGAFLVLERAWLGRHLRRLPPGVSHLYLVLVVMLGWVWFRAETFSGAIDIYRGLLGFNGFSDQSLALGFGLHPLSAAALVAGGLLGFWRWRRPALLKGEGWVAVGADYVMVAALMLVCVLWVGGGSGTPFLYYRF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9X4</accession>
    <name>GATC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatC</name>
        <name type="ordered locus">AZC_2843</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171367.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I9X4"/>
    <dbReference type="SMR" id="A8I9X4"/>
    <dbReference type="STRING" id="438753.AZC_2843"/>
    <dbReference type="EnsemblBacteria" id="BAF88841">
        <property type="protein sequence ID" value="BAF88841"/>
        <property type="gene ID" value="AZC_2843"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2843"/>
    <dbReference type="eggNOG" id="COG0721">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105899_2_0_5"/>
    <dbReference type="OMA" id="VTPMAMK"/>
    <dbReference type="OrthoDB" id="1780195at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
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        <property type="entry name" value="PTHR15004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071382" description="Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <sequence length="95" mass="10369" checksum="AA369FC28B9F792E" modified="2007-12-04" version="1">MSVDQATVRRVAHLARIAVSEEELEPLKGELNAILAFVEQLANLDVADVEPMTGVIPMELPMREDVVTDGHYPEKILANAPEAEGGFFTVPKVVE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAS9</accession>
    <name>RS10_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsJ</name>
        <name type="ordered locus">AZC_2555</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_2555"/>
    <dbReference type="PRIDE" id="A8IAS9"/>
    <dbReference type="EnsemblBacteria" id="BAF88553">
        <property type="protein sequence ID" value="BAF88553"/>
        <property type="gene ID" value="AZC_2555"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2555"/>
    <dbReference type="eggNOG" id="COG0051">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_122625_1_3_5"/>
    <dbReference type="OMA" id="QFEIRVH"/>
    <dbReference type="OrthoDB" id="2012682at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:translation"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000072459" description="30S ribosomal protein S10">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <sequence length="102" mass="11610" checksum="CF70833680926736" modified="2007-12-04" version="1">MNGQNIRIRLKAFDHRILDASTREIVATAKRTGAQVRGPIPLPTRIEKFTVNRSPHIDKKSREQFEMRTHKRLLDIVDPTPQTVDALMKLDLAAGVDVEIKL</sequence>
</entry>
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    <accession>A8IB18</accession>
    <name>A8IB18_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ompA</name>
        <name evidence="5" type="ordered locus">AZC_2596</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2596"/>
    <dbReference type="EnsemblBacteria" id="BAF88594">
        <property type="protein sequence ID" value="BAF88594"/>
        <property type="gene ID" value="AZC_2596"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2596"/>
    <dbReference type="eggNOG" id="COG1360">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3455">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041790_0_0_5"/>
    <dbReference type="OMA" id="TPWGTRG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017733">
        <property type="entry name" value="OmpA/MotB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017732">
        <property type="entry name" value="T4/T6SS_DotU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038522">
        <property type="entry name" value="T4/T6SS_DotU_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09850">
        <property type="entry name" value="DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03349">
        <property type="entry name" value="IV_VI_DotU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03350">
        <property type="entry name" value="type_VI_ompA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="375"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="494" mass="53060" checksum="1739FE3747013E9A" modified="2007-12-04" version="1">MARDTDPQSDAETTIVAPAARWRAPANEQPVSQVAPGRAAPVGTFPFPRPPGSDGRLKPVEREAPRKGPAAPTVPPLPTARTDDRALKAALEVYQDNPGLALAVPIFELLVRAQLQPTGDADEFHDHLLDELQTFETQAISRGLSQQHTRLILYAIAATADDCILNTRWGNESDWAAKTLVSALFQETWGGERFFGLLNQMMAAPHSVVREIEFYYFCLQFGFEGKYRLAANGSGELTRLKDDVFQFLRSVRGGVKPELSPNWRGLSAENQGPGDLLPLVFYGAGIALFLLLLFIGYSLVLRREANLAVQQVQNLMAEPVVIRTPPVATAAAAPAPAPTPAAPPAPKPPAETPLQVISGFLEPEQQAKLITVFGRGNSVVIQTQQELFASASTTLRPPYPEVIAKVAAALAKFKGPVNVLGYTDNVPIRTATFPDNLALSTARARAVGQALAAGLGGNARITTVGKGDADPVASNDTPDGRQKNRRVEIVLTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB36</accession>
    <name>A8IB36_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2604</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171128.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2604"/>
    <dbReference type="EnsemblBacteria" id="BAF88602">
        <property type="protein sequence ID" value="BAF88602"/>
        <property type="gene ID" value="AZC_2604"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2604"/>
    <dbReference type="eggNOG" id="COG3519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028593_2_0_5"/>
    <dbReference type="OMA" id="RTCYPVE"/>
    <dbReference type="OrthoDB" id="140284at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010272">
        <property type="entry name" value="T6SS_TssF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35370">
        <property type="entry name" value="PTHR35370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05947">
        <property type="entry name" value="T6SS_TssF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028304">
        <property type="entry name" value="UCP028304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03359">
        <property type="entry name" value="VI_chp_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="607" mass="67053" checksum="EC173D20C785807B" modified="2007-12-04" version="1">MSDHLLPYYNRELLYLRRMAQEFAARHPKIAGNLRMSGDGIDDPHVARLAEGVAFLNARIAHKLDDEFPELVNTMLDILYPNYLAPIPSMATVQFKPKPEVTTPQTIPVDTELDSEPVDSETCRFRTRYPVTLWPVTVADASLKGRPIVAPSGPRTAGAFSCLRLTLRCSAPDTTFSDLQPDHLRFFLRGQPSHVYALHEMLFNNAVAVALADSASDPTPVLLPPTAIRPVGFGPDEVILPYPAQSQPAYRTLTEFFVFPDKFLYFDVDLSTKVLGNAGAELSVFIYFNKSDLALERSISKEFFALGCTPIVNLFRQRSEPVIVGHNRLEYRVIADARRPEALEIHSLNSVVATDAEGRRKTISPFYARRPKGDETHAGYWAMARRKSEGRLSGTEVFLSFSEIDPAFASTDIVVSAETLCLNRDLPARLPYGGGHPKLTPVQAAAAIGEVNCISPLTHTIRVPEGESRNWRLISHLLLNHLSLVGAGGLEALQEILMLYDFRGSPETRLMIEGITDLSARRGTARAPRRPGDAAWGDAICQGIDLAVEFNPANFSGSSLFLFAMVLDQFFGLHASINSFTRLTATVKGQPGILRTWPARAGFRPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBG8</accession>
    <name>A8IBG8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">secG</name>
        <name evidence="13" type="ordered locus">AZC_3068</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cell membrane</location>
            <topology evidence="2 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171592.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3068"/>
    <dbReference type="EnsemblBacteria" id="BAF89066">
        <property type="protein sequence ID" value="BAF89066"/>
        <property type="gene ID" value="AZC_3068"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3068"/>
    <dbReference type="eggNOG" id="COG1314">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094156_5_0_5"/>
    <dbReference type="OMA" id="VIHLMIV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="2 3" key="5">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Lee KB."/>
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        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="60"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="431" mass="45497" checksum="99B18F330D64F54E" modified="2007-12-04" version="1">MTEPHPLLLANARVIDPSRGADFRGDVLLASGVIKDAAFGIAAAGVPDGAEVVDCKGAVVAPGLVDMRAFIGEPGAEHRETLASASHAAAAGGVTTIVCQPDTDPVVDDPAIVDFILRRARDTAVVRIHPMAALTKGLKGEEMTEIGLLQAAGAVAFTDGARSIASAQGLRRMLTYARDFDALIVHHTEDATMSGGAMNEGLFASRLGLPGIPKAAETIVLERDLRLVDGVRGRYHAASITCRESLEVLARAKEAGLAVTGSVSINHLSFNELDVGQYRTFFKVSPPLRAEDDRVALIQALSSGLIDVVVSDHNPQDVEMKRLPFSEAEPGAIGLETLLSAALRLVHAGDVDLVNVLRALSTRPAELLGLKGGTLKAGSPADVIVLDPEMPWVLDPANLKSRSRNTPFDGARLQGRVLRTIVAGRTVYEYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID51</accession>
    <name>A8ID51_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate (FAA) hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2883</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2883"/>
    <dbReference type="EnsemblBacteria" id="BAF88881">
        <property type="protein sequence ID" value="BAF88881"/>
        <property type="gene ID" value="AZC_2883"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2883"/>
    <dbReference type="eggNOG" id="COG0179">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028458_3_0_5"/>
    <dbReference type="OMA" id="AKHIDYG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="80"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="288" mass="30739" checksum="5B9AE0AD533C1168" modified="2007-12-04" version="1">MFKEKVRPMKFASFTHAGRASYGLVTDGGIVDLARRFPEAPTLRSFIAGGLERAAAFTAAPADVALDDVALDPVIPDPDKIVCVGLNYHDHVTETGRTVTPNPMLFARYPGSQVGSGAALVKPLESDEFDYEGELAVIIGKGGRRISEADALSHVAGYACYNDASVRDWQRHTSQFMPGKTFAATGGFGPWMVSADEIPDPTQLKLTTRLNGQQVQQTSVDLMITPIPTLIAYTSTILPLLPGDVIVSGTPGGVGARRTPKLFMKDGDVVEVEVSGVGVLRNPVVAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID88</accession>
    <name>A8ID88_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Sec translocon accessory complex subunit YajC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 13" type="primary">yajC</name>
        <name evidence="13" type="ordered locus">AZC_2895</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 12">The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 12">Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the YajC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171419.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2895"/>
    <dbReference type="EnsemblBacteria" id="BAF88893">
        <property type="protein sequence ID" value="BAF88893"/>
        <property type="gene ID" value="AZC_2895"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2895"/>
    <dbReference type="eggNOG" id="COG1862">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_116157_2_0_5"/>
    <dbReference type="OMA" id="GMEMIIM"/>
    <dbReference type="OrthoDB" id="2082059at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0811">Translocation</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004377"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00011718"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014962"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF88893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="114" mass="12303" checksum="E7796AA48D8913DA" modified="2007-12-04" version="1">MFISPAFAQGAAPAAGGADMLIQLAPFVLIFVVMYFLILRPQQKKAKAHQEMVNSLRRGDVVITNGGLVGKVVKVVDDAEIEMQIADNVKVRQLRSQIAVVRSKGEPAKDETAA</sequence>
</entry>
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    <accession>A8IDB3</accession>
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            <fullName evidence="8">ABC-type uncharacterized transport ATPase component</fullName>
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        <name evidence="8" type="ordered locus">AZC_2907</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171431.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2907"/>
    <dbReference type="EnsemblBacteria" id="BAF88905">
        <property type="protein sequence ID" value="BAF88905"/>
        <property type="gene ID" value="AZC_2907"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2907"/>
    <dbReference type="eggNOG" id="COG4608">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_5"/>
    <dbReference type="OMA" id="VFYKGQD"/>
    <dbReference type="OrthoDB" id="1303270at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="23"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="58"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="337" mass="36454" checksum="975CF4107660F4FA" modified="2007-12-04" version="1">MSPPFLAASALSRRFSPNIPLTSRLIGALGGKAAPRSVHAVDGVDLAVTKGEALGLVGESGCGKTTLGRMIAGILPPSDGTVAIAGQPVMSGGATPRKTTTRVQMVFQDPFASLDPRMRIGDTLSEGPVHHGLVPRAEARAYVRGWLTRVGLDPDYADRYPHQFSGGQRQRIAIARALAMQPDVLVCDEPVASLDVSIQAQIINLFLKLRRELDLTLLFISHDLSVVRHLCDRVAIMYLGRIVEEGPTDQVYADPRHPYTQALLDSVPKLVTEEGTDVTFRPIAGELPSPLAPPPGCHFHGRCPRAEARCRTERPLLRPVAPQRTAACHFARIDQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
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    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2909</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88910.1"/>
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    </evidence>
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        <source>
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    <sequence length="223" mass="25493" checksum="DEA05273C54952B8" modified="2007-12-04" version="1">MQSRKWFRLKLVKQIDRAQNLLSSFTMNQLEKGRPRRSEGGERMHAPQLPPSAAEEDLPGDVDPLIAIKLWRNPCWFSFRINYLSMNFNVPVYGWTEKTFGLPRPEFVVLYALGLKGGVAAKDICSSSGFPKPTISRAIQSLLKRKLVRRDTDPKDHRSYVLNITDDGQSIFDASMPVMLERERVMLARLSPGERAMLFEILAKMVVDSPEWPQTIETEDTLP</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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    </evidence>
    <sequence length="393" mass="41106" checksum="ABB2767CD4134686" modified="2007-12-04" version="1">MPPVHCGHAPFVPYGTHVSKGEEMAADVSGPMPKSAWLYPIVALGYFGLATGLGFDEGFTGSTSGILLAIVLIPVIFGAIFAAVYHAEVIGHATGEPFGTLVLTAAVTIIEVALIASVMLSDDGGSPELARDTVFSVVMTVCTGLTGICILGGGLRFKEQVYETTGAGAYLTVLIVLVTLTLVLPNYTQGTPGPFYSSSQLAFFSVLTLILYGVFLYIQMVRHRDYFVSSNGSVVAVEHAIPTARALLSAGLLFAALTAIVLLSKKFAIVVEAGREAVGSPPAVTGLIVAILILLPESIPAFQAARRDQLQKSLNLALGSSLATIGMTFPAVAVVSLALNKPLVLGLTPRDTVLMATTLLVSSLTLGSGRTNILYGFTHLVIFAAFLFLTFQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IE51</accession>
    <name>A8IE51_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Argininosuccinate lyase</fullName>
            <ecNumber evidence="3">4.3.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171561.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3037"/>
    <dbReference type="EnsemblBacteria" id="BAF89035">
        <property type="protein sequence ID" value="BAF89035"/>
        <property type="gene ID" value="AZC_3037"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3037"/>
    <dbReference type="eggNOG" id="COG0165">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027272_3_5_5"/>
    <dbReference type="OMA" id="YTNGVAA"/>
    <dbReference type="OrthoDB" id="751464at2"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724427" description="Argininosuccinate lyase" evidence="5">
        <location>
            <begin position="26"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="100"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="370"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="505" mass="55185" checksum="9F2890BE30A12E7C" modified="2007-12-04" version="1">MRMAAKVAGAVMMSALTLSTGTAQAQSEARRDEFYWLGEINKASLVINSSQGLLDPALAPRIAQGLDKVLKDGARPGAKRPTLVITFEPLLIEAAGVEATLLHAGRSSQDMLSTVRAAVMRDELLALAEQLRTTTATLRAVAEAQQDTIVPNYTNGVAAQPNSYGHYLLGFVAGFERDAERLRQAYARLDRSPMGTTVLNGTSWPLDRDRMAAYLGFPAKVDNAYDAAQISAAEMPVEIGAVATSIALHTGAFIQDVMVQYAQPRPWILLREGDGNTYVSSAMPQKRNPGLLNDTRGQASMVLTLAMGRAIAAHNIPPGMNDPKSVRDNAEVITRTVATLRNLDRILKALVIDRDRALEELNSDWTASQEIADELMRTYKLPFRVGHHFASEVVGYAKAHDIRPSDFPYAEAQRIYRETLAEMKLPVGELPMSEAQFRAALDPVAILRNRATSGGPQPAEMKRMLAETDQNLAAQQRWISEHRQAIDTALARLDSDFAQVLAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IE57</accession>
    <name>A8IE57_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative AgaF protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">agaF</name>
        <name evidence="3" type="ordered locus">AZC_3039</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171563.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3039"/>
    <dbReference type="EnsemblBacteria" id="BAF89037">
        <property type="protein sequence ID" value="BAF89037"/>
        <property type="gene ID" value="AZC_3039"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3039"/>
    <dbReference type="eggNOG" id="COG0145">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002157_1_2_5"/>
    <dbReference type="OMA" id="CYNRGGT"/>
    <dbReference type="OrthoDB" id="327092at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="209"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="690" mass="73618" checksum="E84EE36D62BA39D1" modified="2007-12-04" version="1">MARWRVGVDSGGTFTDICLFDEDEGRVEVWKVSSTPDDPSRGIAEGVEQGMRRVAPENGDKPASSVAYFGHGTTVATNALIQHRGVATGLVTTDGFRDLLEIGRQKRPDLYDLTADKPPTLVPRALRMAVGERVRHDGSIDLPLDEPAVREAAKALKKAGVKAIAVSFLYGFVRPEHEARAVEIIREEYPEAFVCSGHEIAPEFREFERLSTVVLNAYLGPVMKSYIERLSPRLEALGMEATPHLTQSNGGVIGFSTAAAMPVRTILSGPSTGVVAAQAVGELAGFPDIITFDMGGTSTDVALLKGGVCKLTSEANVHGYPLKAPMLDIHTVGAGGGSIAYVDSGGLLKVGPRSCGAFPGPVCYDKGNEEPATTDANVVLQTLNPTHLLAGRMPVRQDLAKAAIGRLADKLGLGVMETAQGILSVVTANMAKAIRVISVQRGHDPRDYTLMAFGGAGPLHAARLAKELDMRRVLVPRNPGILCAMGLLLTDLRADFAATKLLPLAASSLAPVSEAFATLSARAQAWFDHEEITAAARQMHRTVDMRYAGQNYELSVALPEGAVTETTLEHLAEAFEEAHRQRYGFIAAGEAVQIVTLRVEAVGLVRKATLKAYPLEGPDASAAIIGKRPVWFPEAGDYVPTPIYDREALKAGNRFAGPAIVEQMDTTTVVPPGMTARVDAYHNLILEVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IE85</accession>
    <name>A8IE85_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_3050</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171574.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3050"/>
    <dbReference type="EnsemblBacteria" id="BAF89048">
        <property type="protein sequence ID" value="BAF89048"/>
        <property type="gene ID" value="AZC_3050"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3050"/>
    <dbReference type="eggNOG" id="COG1760">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022305_0_1_5"/>
    <dbReference type="OMA" id="HLAMIRK"/>
    <dbReference type="OrthoDB" id="225730at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="180"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF89048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="450" mass="47067" checksum="921D86E7202BD44C" modified="2007-12-04" version="1">MISVFDLFKIGVGPSSSHTVGPMVAAKRFRDELPVGTAHVTAEIFGSLAWTGKGHATDRALCLGLIGAVPATLEPDDVPALIARLAIEKAIETPDGGRATFDPDADLIFDFKTLLPRHTNAMRFRAYDGAGALTQERIFYSVGGGFVVEDGENEAPLGTAQVPYPFDCAADMLTVCARTGLDVAGVQMANECALRSRAEVEGGLDAIADAMFGCIERGLSMDGSLPGRLRVKRRAKAIREKLEADRGLNQRPPHEIMDWVSVFAIAVNEENAAGGRVVTAPTNGAAGIVPAVLRYARDFCPDVGPEQVRCFLLTAAAVGGLIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPEQIENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAAASLALRGDGIHNVSLDQVIETMRQTGADMQSKYKETSQGGLAVNVPEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEH8</accession>
    <name>A8IEH8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3493</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172054.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3531"/>
    <dbReference type="EnsemblBacteria" id="BAF89529">
        <property type="protein sequence ID" value="BAF89529"/>
        <property type="gene ID" value="AZC_3531"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3531"/>
    <dbReference type="eggNOG" id="COG3237">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_135567_3_2_5"/>
    <dbReference type="OMA" id="NYGDAKE"/>
    <dbReference type="OrthoDB" id="2089955at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="3">
        <location>
            <begin position="6"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="64" mass="6645" checksum="20E3DE69606FB3D7" modified="2007-12-04" version="1">MGSTSDKISGMANEAMGNVKQGIGKATGNDRLRAEGKVQEIKGEGQQTLGKAKDAVKDAVDRTP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEY6</accession>
    <name>THIG_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiazole synthase</fullName>
            <ecNumber evidence="1">2.8.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">thiG</name>
        <name type="ordered locus">AZC_3552</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + [sulfur-carrier protein ThiS]-C-terminal Gly-NH-CH2-C(O)SH = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS]-C-terminal Gly-Gly + 2 H(+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:26297"/>
            <dbReference type="Rhea" id="RHEA-COMP:12908"/>
            <dbReference type="Rhea" id="RHEA-COMP:12909"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:90619"/>
            <dbReference type="ChEBI" id="CHEBI:90778"/>
            <dbReference type="EC" id="2.8.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer. Forms heterodimers with either ThiH or ThiS.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ThiG family.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.10" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172075.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IEY6"/>
    <dbReference type="SMR" id="A8IEY6"/>
    <dbReference type="STRING" id="438753.AZC_3552"/>
    <dbReference type="EnsemblBacteria" id="BAF89550">
        <property type="protein sequence ID" value="BAF89550"/>
        <property type="gene ID" value="AZC_3552"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3552"/>
    <dbReference type="eggNOG" id="COG2022">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062233_1_0_5"/>
    <dbReference type="OMA" id="PHNFQLI"/>
    <dbReference type="OrthoDB" id="784095at2"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990107">
        <property type="term" value="F:thiazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04728">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00443">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033983">
        <property type="entry name" value="Thiazole_synthase_ThiG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008867">
        <property type="entry name" value="ThiG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34266">
        <property type="entry name" value="PTHR34266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05690">
        <property type="entry name" value="ThiG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0704">Schiff base</keyword>
    <keyword id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000072334" description="Thiazole synthase">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with DXP" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="194"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="216"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00443"/>
        </source>
    </evidence>
    <sequence length="266" mass="28125" checksum="6E539590A1794DFB" modified="2007-12-04" version="1">MNVNVPVPSTLADPLVIAGRTFSSRLFLGTAGYPNQKVFLDALEASGSEMATASIRRMSLEGYEESLADLLTGRVHILPNTAGCQTAKDAILTAELAREALETDWVKLEVIGDRELLYPNVEELLKATEELVNRGFVVLPYCNDDPVTCQKLADLGAATVMPLGSMIGTGLGIANPHMIELICARSPVPVVLDAGIGTASDAAQAMELGCAAVLLNTAVSKAHDPVRMARAFRYAVEGGRLARLAGRIPKKLHAEASSPEFGLVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF05</accession>
    <name>A8IF05_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="Pfam" id="PF01494"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    <dbReference type="STRING" id="438753.AZC_3572"/>
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        <property type="gene ID" value="AZC_3572"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3572"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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            <dbReference type="EMBL" id="BAF89570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <sequence length="109" mass="12650" checksum="03EA5DBB0BC00F77" modified="2007-12-04" version="1">MQRWEYFKARGRTYAVPYCHPSRPVEGWVKDRKGLRPMRTKPRYMRLTQTLITEDEARRRAPDLVAVIEEEVVALLEALGDLEAELVAERTKATEALALVETLRLPKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF70</accession>
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        <name evidence="1" type="ordered locus">AZC_3584</name>
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    <organism evidence="1 2">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki T."/>
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                <person name="Miwa H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <dbReference type="Pfam" id="PF17212">
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89582.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="200" mass="22582" checksum="26C39A52715BB91C" modified="2007-12-04" version="1">MMPVRLTTELDAINTMLSIIGEAPVNRVEDTGLVDAVMARQILDETMRQVQSHGWHWNTDKNVVLVPSFPAPGDVYVPDNTLQVDAMDPSIDVVQRGNRLWDRRNNTFKFSVPVEVEIVRLLPFEELPQIARHYIMVRAGRIFQDRVVGSETLSGFNDKDETRALIALRNAEAETADYNMLSDSWAVGRVLNRRSGGFEG</sequence>
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    <accession>A8IFD8</accession>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <cofactor evidence="4">
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        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
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        <text evidence="4">Divalent metal cations. Prefers magnesium or manganese.</text>
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    <comment type="similarity">
        <text evidence="1 5">Belongs to the malic enzymes family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
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    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="7">
        <location>
            <begin position="91"/>
            <end position="271"/>
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    <feature type="domain" description="Malic_M" evidence="6">
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            <end position="532"/>
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            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
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            <dbReference type="RuleBase" id="RU003427"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
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    </evidence>
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        <name evidence="5" type="ordered locus">AZC_0134</name>
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    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="subcellular location">
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    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
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        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
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        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Peptide/Ni-bd"/>
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    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
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    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
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        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="134"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="649" mass="72043" checksum="96BD05B5B6BA5CCA" modified="2007-12-04" version="1">MSAGTDRRTLLRLAAAGGAAAFLPGLGAGRARAQTPPPAPASEGGAAAPAVERHGLSSFGELKYPKDFKNFDYVFPGAPKGGTFSQIGPTAAYNQSFQTFNSLNGYILRGDGAQGIALIFDSLMVRASDEPDAVYGLVASSVSISDDGRTYRFRLRPEARFHDGTPLTAEDVAFSLNTLKAQGHPLIRQALREFTGAEAEDKGTVVLSFTAQRPRDVPSYAATLPIFSKAYYGKHKFEETTLDPPLGSGPYKVGRFEVGRFIEYLRVADYWAADLPVNRGRHNFDVLRFEYFRDREVGFEAFKARAYLFREEFTSRAWATQYDFPALKTGRVKREVLPDETPSGAQGWFFNTRRAKFLDPRVREAIALAFDFEWTNKNLMFGQYERTWSFFQNSDLMAKGLPSPAEEKLLAPFRDALPAEVFGEPYVPPVSDGSGQDRALLRRAAALLKDAGYTIQQGRLVDGKGTALTIEFLDDDGAFERHTSRFIANLKLLGIEASFRIVDPAQYQARLKDFDFDMVVRRYSVSLNPGDELRAYFGSEAARLPGSNNLSGISDKVVDALIADAIAAQTRADLVTACRALDRVLRAGRYWVPQWNKASFWIAYWDVFDRPAVKPKYDRGTPDTWWWRKGIADPPPVVEPGPASPQKDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGY4</accession>
    <name>A8IGY4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0151</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0151"/>
    <dbReference type="EnsemblBacteria" id="BAF86149">
        <property type="protein sequence ID" value="BAF86149"/>
        <property type="gene ID" value="AZC_0151"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0151"/>
    <dbReference type="eggNOG" id="COG4291">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098677_1_0_5"/>
    <dbReference type="OMA" id="IFSLHYA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009781">
        <property type="entry name" value="DUF1345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07077">
        <property type="entry name" value="DUF1345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="253" mass="26825" checksum="ADE03AAEC7BC840E" modified="2007-12-04" version="1">MAADAKTSPRPHAGMMPHEHAIRTTKAPMSRSTPPVPTLGAALRRGVRLHRRLAIAVGVAIVIVLFAPMLSFRTRLLVGWDAGIALWLILTLHMVNGSNAAKIRARAAEEDEGAAAILIGCLLASFSSLVAVVMEAGATAHASGAAAAHILLAIGTLALSWCFIHGIYALHYAREYYAPDVDCHPMLGFPGSQEPDAWDFMYFSFTIGTSAQTADVSVNSARMRRFVLGHQLVAYAFNASVLALGVNVAAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHB7</accession>
    <name>A8IHB7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetylornithine deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0201</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family. ArgE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168732.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0201"/>
    <dbReference type="MEROPS" id="M20.974"/>
    <dbReference type="EnsemblBacteria" id="BAF86199">
        <property type="protein sequence ID" value="BAF86199"/>
        <property type="gene ID" value="AZC_0201"/>
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    <dbReference type="KEGG" id="azc:AZC_0201"/>
    <dbReference type="eggNOG" id="COG0624">
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    <dbReference type="HOGENOM" id="CLU_021802_2_4_5"/>
    <dbReference type="OMA" id="VSGHKGM"/>
    <dbReference type="OrthoDB" id="906744at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008777">
        <property type="term" value="F:acetylornithine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010169">
        <property type="entry name" value="AcOrn-deacetyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
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        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01892">
        <property type="entry name" value="AcOrn-deacetyl"/>
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    </dbReference>
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        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
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    </dbReference>
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        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="4">
        <location>
            <begin position="169"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="382" mass="40620" checksum="3565797B89795D0A" modified="2007-12-04" version="1">MSTLDLLDRLIAFPTVSRDPNRELIAFVQAFLGQHGIASEIIATPDGRKANLFATIGPTDRPGIMLSGHTDVVPVEGQAWTADPFRLRVADGRAYGRGAADMKGFLAAALALAARAAARPLETPLHLALSHDEEVGCVGVRSLIERLSTASVRPRLCIIGEPTSLRVATGHKGKLAARATCCGVEGHSALAPKALNAIHLACDFVGLLRTHQDRIAESGARDADYDIPYTTLHAGVIAGGTALNIVPNRCTVDFEIRNIAQDDASEVLTRLLDDAARLVAERRAAFPAADIAVEVVNDYPGLATPKEAEVVAFVQALVDDASTFKVAFGTEGGLFDARLSIPTVICGPGSMDQGHKPDEFIALDQLEACDRMMDRLLHRLAA</sequence>
</entry>
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    <name>A8IHD6_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">AAA_23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3261</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171785.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3261"/>
    <dbReference type="EnsemblBacteria" id="BAF89259">
        <property type="protein sequence ID" value="BAF89259"/>
        <property type="gene ID" value="AZC_3261"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3261"/>
    <dbReference type="eggNOG" id="COG0419">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_573246_0_0_5"/>
    <dbReference type="OrthoDB" id="34070at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="1">
        <location>
            <begin position="11"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="476" mass="49912" checksum="03E355251AA651AD" modified="2007-12-04" version="1">MSRYFLASAAIEGFRGINNDGDPLVLKFKHDAVNSVHAPNGVGKSSIFEALHFALHGTVPRLEGMQDAEQGASYIVNKFHPAQQATVALVFKSDDGTPDVSITVTRTAAGGRVVTSPSGHADPDSFLADLCEDFVLVDYPRFASLVDCSALERGRSFASLVGMSRYSQLRQALDGAKNTRNINGDLGLSTLYTEVTAENRALGAVEQRILAAHQEVTGAAGGQMADTAALKAQVTAGLAGIALFAPLLANASVMDFDFDAAEKIVDQEEGGAARKTLDGLNTAVTTLGGLQVSAAELAEIDALVTAAKARDDAMRKVGAASLHALMKSALSVVNSADWHDPKVCPVCEKAGDGPLQEQLEAKIALYDEADQFDAELKRQVQSAGCVGKLRQLEEQARLGVVDADRIAPVLTLAARQSSVSTADLERAQDALGTLEAKRVDVLAAINAEIATLQASLPPSLVAVTRDLPLLSGPACV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHX0</accession>
    <name>A8IHX0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3332</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3332"/>
    <dbReference type="EnsemblBacteria" id="BAF89330">
        <property type="protein sequence ID" value="BAF89330"/>
        <property type="gene ID" value="AZC_3332"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3332"/>
    <dbReference type="eggNOG" id="ENOG502ZBQX">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_699827_0_0_5"/>
    <dbReference type="OMA" id="GAWIAVF"/>
    <dbReference type="OrthoDB" id="431175at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721060" evidence="1">
        <location>
            <begin position="21"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="383" mass="41473" checksum="FB5299D0F4001E01" modified="2007-12-04" version="1">MLRRALLALGGALLILRGTAASGLELSVAGPEFIVFDQRTQACDTSDLPDAPARAFRNAQGQMVLFAPNFRNRAFEGPDLRHLARDCAVRFAARQSADPGQLDDRTWLHAFHTTDGTHIFALASASFIPYRHGEACAAGRERTACWSNGIAALSSQDGGRSFSYTAPPPRHVLMPPQPFTPQVRDPAGFVSATNIVSYKGDLYSIVWRREADGKRSRNCLVRAPGGDVRRWEMWTGEGFAPMAQEGPAGWQVEGTDCAAVGRGLPAIRGLVLHPTSGTFIAVFQMRPRGPTGGEDGFYTATSKDMVTWSAPRLLLAQPLRDGLDDHGTFAGYPTLIDDKSPDRDFGTVGPQADLVFVRFMELGAGGPKGRNRQLVAVPLRITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8II15</accession>
    <name>A8II15_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Methyl-accepting chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3349</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3349"/>
    <dbReference type="EnsemblBacteria" id="BAF89347">
        <property type="protein sequence ID" value="BAF89347"/>
        <property type="gene ID" value="AZC_3349"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3349"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_32_5"/>
    <dbReference type="OMA" id="ERCKQCH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035438">
        <property type="term" value="F:cyclic-di-GMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009875">
        <property type="entry name" value="PilZ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07238">
        <property type="entry name" value="PilZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="47"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="213"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="581" mass="61586" checksum="AEE07CBA94B9CC09" modified="2007-12-04" version="1">MFGLWDKQKTANSRQQVAKPEPVVVEKAAPPPQPELRTGDAELVALLETDIRRAETKLAGAGAAMRAAAAAGVRDLEHIRADSEVMSAETASAKENAASLARAIGAFAETATEIGRQAQTSGRLAGEAETANQAVTAATQELHVAISQIQAVVALISDIASQTNLLALNASIEAARAGTAGAGFAVVASEVKALAGETQKATKEISEKIDRLEAAAKASETAVQRVSGTIAEIRPVAARVAEAVAGQVGAIDEIGRSAEEVERFAEVVADRARSISSATGAAAQTSAEIEQRTGDMTHNVEEMSRHLLSVLRQTPLGDRRKFDRWPVEISGRLSHAGGTASVKTLDLSMGGALLAAVTPTPRVGERITLDLPGLGALPGRIAANSPLGCHIAFERTDHAAVESRIAAIAREAADAIARAQRGAETVREAFARALAAGRISRDALFDTTYRTLPGTDPEQVETRALSFLESTLPPLQEPMLGEDGRLAFCVAVDVNGYLPVHNAQYSKPQRPGDPAWNNANSRNRRIFDDRAGLLAARNTKPFLVQVYARHIGGQVIMMREVDAPIIIEGRHWGAFRTCYRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A8II47</accession>
    <name>A8II47_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3361</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0208"/>
    <dbReference type="EnsemblBacteria" id="BAF86206">
        <property type="protein sequence ID" value="BAF86206"/>
        <property type="gene ID" value="AZC_0208"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0208"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_0_5"/>
    <dbReference type="OMA" id="QGTYSEY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08252">
        <property type="entry name" value="AL_MDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014182">
        <property type="entry name" value="ADH_Zn_typ-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02817">
        <property type="entry name" value="adh_fam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="12"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU364000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="339" mass="36289" checksum="721FBC61D450B68A" modified="2007-12-04" version="1">MSMKAIGYRQSGPIDRDDALVDIEIDRPAARGRDLLVEVAAISVNPVDTKVRKRAAPPEGEWKILGWDAVGRVVEVGEGVTRFRPGDEVYYAGSLTRPGANSAFHLVDERIVGRKPATLSNPEAAALPLTAITAWEMLFDRLDIVKSVPGAANAILIVGGAGGVGSIAIQLVRALTDLTVIATASRPETQDWVRALGAHHVVDHSAPIAAQVAALGLGAPAFVFSTTETHRHLAEIAELIAPQGRFGLIDDPDGLDVSVFKRKSVSTHWEFMFTRSMFETADMDAQGRLLDEVARLVEAGKVRTTLTQTLRPISAATLKTAHAILESGKARGKIVVEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIZ3</accession>
    <name>A8IIZ3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent protease subunit HslV</fullName>
            <ecNumber evidence="7">3.4.25.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hslV</name>
        <name evidence="8" type="ordered locus">AZC_0222</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP-dependent cleavage of peptide bonds with broad specificity.</text>
            <dbReference type="EC" id="3.4.25.2"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Allosterically activated by HslU binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase T1B family. HslV subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.2" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0222"/>
    <dbReference type="MEROPS" id="T01.006"/>
    <dbReference type="EnsemblBacteria" id="BAF86220">
        <property type="protein sequence ID" value="BAF86220"/>
        <property type="gene ID" value="AZC_0222"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0222"/>
    <dbReference type="eggNOG" id="COG5405">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_093872_1_0_5"/>
    <dbReference type="OMA" id="IMKGNAR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01913">
        <property type="entry name" value="protease_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00248">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022281">
        <property type="entry name" value="ATP-dep_Prtase_HsIV_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="PTHR32194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039093">
        <property type="entry name" value="HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03692">
        <property type="entry name" value="ATP_dep_HslV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0915">Sodium</keyword>
    <keyword evidence="4 7" id="KW-0888">Threonine protease</keyword>
    <feature type="active site" evidence="7">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Na(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="197" mass="21251" checksum="FC3AA44789C0DBE3" modified="2007-12-04" version="1">MHRRRKVLSKAPSAEPYMHSPDTIYGTTIVTVRKGNRVAIAGDGQVTLGQTVLKANARKVRRLGKGDVIGGFAGATADAFTLFERLEAKLEQYPGQLQRAAVELAKDWRTDRYLRRLEAMMIVADANVSLVLTGTGDVLEPEAGVAGIGSGGMYALAAARALLDREDAPEAIVRRSLEIAADICVYTNRNIIVETIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ21</accession>
    <name>A8IJ21_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0236</name>
    </gene>
    <organism evidence="5 6">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86253.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="507" mass="54653" checksum="8DE38C90042F5AA9" modified="2007-12-04" version="1">MCRGFEMIERVRGLFAYFARVVPFRIKPAIITTLVLFTLLLLPVPAGLTPKAWALVAIFLTTIVAIILKVMPIGVMAMMAMTIVALSQVTATSSKAAIADALASLSNPLIWLIVVAIFISRGLKKTGLGSRIGLLFIALLGRRTIGIGYGLAVCELVLAPFTPSNTARGGGIVHPIMKSIAGAFGSDPAKGTERKMGTYLALVNMHANPITSGMFITATAPNPLVVDYVAKVTNQSFHLTWTSWALYMLLPGLVCLLLMPLAIALLSPPEVKATPDAVDYARGELKRMGALSGGEWVMIGTFLLLLVLWANVPAMIFGKAFELDPTAVAFLGLFALIITGTIDWDDVLSEKSAWDTLIWFGALVMMAEQLNKTGVIAWFSNLLKSGILASGMGWQPAAALLVLCFVFSHYFFASTTAHISAMMLAFLTVGLQIVPPDFHIPFLLMMASGSAIMMTLTHYATGTSPIIFGSGYVGLGLWWRVGFVMCVIELLIYAVVGNLWWKVLGLW</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0322"/>
    <dbReference type="EnsemblBacteria" id="BAF86320">
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    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0322"/>
    <dbReference type="eggNOG" id="COG4666">
        <property type="taxonomic scope" value="Bacteria"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="Pfam" id="PF06808"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF86320.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="737" mass="77439" checksum="DAFB829597859571" modified="2007-12-04" version="1">MGAVGCPPARVFLLPHRVAASGGADPWSDAFMSTPSIPADSDITPPQTFAPIDDMEHGLPPGFGTGFKGTLLFWIAIAFSAYQLFVSTYAILPSQVIRALHVGFLCLISAALIANHRSTNKATLALGWGLGLIGFGTGLYQWIFYNDLILRAGEISQADFVMGIALIVVVFVISWQMMGAALPLICGAFLLYGLFGQYLPAPLDHRGYSLEQIVEQMSFGTEGIYGTPIAVSATYIFLFVLFGTFLERAGMIQLFNDIALGLFGRARGGPAKVAVFSSALMGTISGSGVANVVTVGQFTIPLMKRFGYSASFAGGVEATASMGGQIMPPVMGAVAFIMAETIGVPYATIVKAAIIPAILYFASAFWMVHLEAGKHGLVGIPKDRVPRVIPALRRGWYLLLPLAVLVYLLFAGYTPLFAGAVGLALTVVLILGQSLAGEAGKPALRLAFWILIGLVCASFFQFGVMVIVGLVLALIVVNGITRGGRATLALCRDGLAEGARQALPVGMACAIVGTVIGVLTLTGTATIFGGWVVSIGKETLWLSLLLTIVTSIILGTGIPTIPTYIITASLAAPAMLSLGVPLIVSHMFVFYYGIIADLTPPVALAALAAAPIAKASPDAIGWQACRIALAGFLIPVMAVYEPTLMLQQGGEIAAHYGYWVEVAYVFTKACIVIGLLGAIAIGWLFGPLGLIERIVAGLAALLFVAAVPMSDISGFALLAVFLGWHLLQVRRAPPRPV</sequence>
</entry>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <dbReference type="STRING" id="438753.AZC_3885"/>
    <dbReference type="EnsemblBacteria" id="BAF89883">
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        <property type="gene ID" value="AZC_3885"/>
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    <dbReference type="OMA" id="DIAMIQR"/>
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    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
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        </location>
        <ligand>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3893"/>
    <dbReference type="EnsemblBacteria" id="BAF89891">
        <property type="protein sequence ID" value="BAF89891"/>
        <property type="gene ID" value="AZC_3893"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3893"/>
    <dbReference type="eggNOG" id="COG0402">
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012358_2_2_5"/>
    <dbReference type="OMA" id="GRRVHMH"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="47"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="481" mass="51363" checksum="E933133EF4838F9A" modified="2007-12-04" version="1">MSEPRTLSCAHLLADPRGAAAGPKRLTLRDGRIEALLAAQGPVDDLFVMPTPVNAHDHGRPVRTSSIGAGGKPLEAWIPYLALFPSVDPYLAAALSLSHSALGGAGVVMMHYTRAQGFTDLPGEVREVARAARDVGVRVGFAIAMKDRNPLVYGPSASVLGGVAEPARSRIERQFLRPSLEPKAFIELADAVAEAAGGPDFDVQYGPNGPQWCSDALLEAVAEASARTGRRVHMHLLESRYQRAWADEAHPGGIVRHLDALGLLSERLTLAHCVWARPDELALLAERGVTIVSNPSSNLHLRSGIGPVAQMKARGCRVAFGVDGRAMDEDDDMLREIRLAHLLHLGTGFKAAVTQNAILEMALVNGRRSVLNRADGGRLAPGEPADLLVLDWARLEDDRLRDDLDAVELVVTRATARHIRELIVGGRTIVRDGAITGIDLRAVRAELLAQMRAGMAGMADLAAALPSLEAAMAAHFEPGCC</sequence>
</entry>
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    <accession>A8ILX9</accession>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168973.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0442"/>
    <dbReference type="EnsemblBacteria" id="BAF86440">
        <property type="protein sequence ID" value="BAF86440"/>
        <property type="gene ID" value="AZC_0442"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0442"/>
    <dbReference type="eggNOG" id="COG3492">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_153226_0_0_5"/>
    <dbReference type="OMA" id="MPYEEWK"/>
    <dbReference type="OrthoDB" id="1902575at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023163">
        <property type="entry name" value="SMc04008-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036810">
        <property type="entry name" value="SMc04008-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06844">
        <property type="entry name" value="DUF1244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158757">
        <property type="entry name" value="SSF158757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1244" evidence="1">
        <location>
            <begin position="30"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="101" mass="11426" checksum="2C88608E7D58653D" modified="2007-12-04" version="1">MTDLSEDERTKLEAAAFRRLVAHLAARTDVQNIDLMNLAGFCRNCLSNWYLDAAQEAGLPLSKDESRQAIYGMPYEDWKALHQREATDAQKAAFEQAKPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM46</accession>
    <name>A8IM46_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169016.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86483">
        <property type="protein sequence ID" value="BAF86483"/>
        <property type="gene ID" value="AZC_0485"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0485"/>
    <dbReference type="eggNOG" id="ENOG50335P7">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_158447_0_4_5"/>
    <dbReference type="OMA" id="EQPGQCY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="89" mass="8194" checksum="8798DA9691B3C8CA" modified="2007-12-04" version="1">MKGAVIVVAAALALAGCSQYSESDRAVGGGLLGAGAGALIGGAATGNATGALVGGALGAATGAVVGAATTPNACWARDAYGNAYQVRCP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-04-14" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM50</accession>
    <name>Y488_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0301 protein AZC_0488</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_0488</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169019.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IM50"/>
    <dbReference type="SMR" id="A8IM50"/>
    <dbReference type="STRING" id="438753.AZC_0488"/>
    <dbReference type="PRIDE" id="A8IM50"/>
    <dbReference type="EnsemblBacteria" id="BAF86486">
        <property type="protein sequence ID" value="BAF86486"/>
        <property type="gene ID" value="AZC_0488"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0488"/>
    <dbReference type="eggNOG" id="COG1678">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_057596_1_0_5"/>
    <dbReference type="OMA" id="IYWGGDF"/>
    <dbReference type="OrthoDB" id="1736059at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00758">
        <property type="entry name" value="UPF0301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000198253" description="UPF0301 protein AZC_0488">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00758"/>
        </source>
    </evidence>
    <sequence length="205" mass="21825" checksum="8BA672C70FC1CE99" modified="2007-12-04" version="1">MMADRTISSPRGPGDFLDGQMLIAMPSMRDERFNRALVYICAHSAEGAMGIVVNQPATHIDFGDLLVQLDVVPATKRIQLPPRAELVKVLRGGPVETGRGFVLHSSDFFLENATLPIDNGICLTASLDILKAIAGGQGPESAVLALGYAGWAPGQLETEIQANGWLHCPADPELIFGESVDAKYDLALRKLGVHPGMLSTDAGHA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM96</accession>
    <name>RUVC_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="1">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ruvC</name>
        <name type="ordered locus">AZC_0513</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RuvC family.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169044.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IM96"/>
    <dbReference type="SMR" id="A8IM96"/>
    <dbReference type="STRING" id="438753.AZC_0513"/>
    <dbReference type="EnsemblBacteria" id="BAF86511">
        <property type="protein sequence ID" value="BAF86511"/>
        <property type="gene ID" value="AZC_0513"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0513"/>
    <dbReference type="eggNOG" id="COG0817">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091257_1_0_5"/>
    <dbReference type="OMA" id="AICHIWR"/>
    <dbReference type="OrthoDB" id="1815080at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Controls the rotational direction of flagella during chemotaxis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliL family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0629"/>
    <dbReference type="EnsemblBacteria" id="BAF86627">
        <property type="protein sequence ID" value="BAF86627"/>
        <property type="gene ID" value="AZC_0629"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0629"/>
    <dbReference type="eggNOG" id="COG1580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125894_1_0_5"/>
    <dbReference type="OMA" id="AYPSENW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005503">
        <property type="entry name" value="FliL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03748">
        <property type="entry name" value="FliL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="10" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="10" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="176" mass="18800" checksum="D5E555BE6E67DAE6" modified="2007-12-04" version="1">MAASDDKAKSATVAAATGAGGKEQNGTKGLILAILILTVLGVATGGGLGVQLATTVEKVVAAKAKEEPVKKEQQLFYAGNTMMQPMKPVIVNLASPPNTWVRIESSFVFKNGALANPALTESTLREDMMSYLRTLTLSQFEGPSALQQLREDLNERARVRSEGRVDELIIETLVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPP4</accession>
    <name>A8IPP4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="4">3.1.1.61</ecNumber>
            <ecNumber evidence="4">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cheB</name>
        <name evidence="9" type="ordered locus">AZC_0664</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="4">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the CheB family.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="4"/>
    <dbReference type="EC" id="3.5.1.44" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169195.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0664"/>
    <dbReference type="EnsemblBacteria" id="BAF86662">
        <property type="protein sequence ID" value="BAF86662"/>
        <property type="gene ID" value="AZC_0664"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0664"/>
    <dbReference type="eggNOG" id="COG2201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_51_0_5"/>
    <dbReference type="OMA" id="MLEMHRA"/>
    <dbReference type="OrthoDB" id="1655418at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="18"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="8">
        <location>
            <begin position="219"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4 6">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="412" mass="42214" checksum="B39E871AA0DC434F" modified="2007-12-04" version="1">MSTSAPSADTGAVEDPIRVMIVDDSVFIRGILSNWLGESPDLRVVATHANGRRAVDDVQKSLPDVVILDLEMPEMDGLTALPLILEKKPNTVVLVASTLTRRGAEVSLKAMSLGAADYVPKPDAGRGISAADEFRRDLTAKVRSLGQRVRRRGSLPRVMAAAAASAAAAPAAAPATAGAAAPAPARPAAPAAGAAPAAPVSAFAKPKVNDKRRPYSMSPVTVLAVGSSTGGPQALTRLFTDIGPSIANVPVVIVQHMPATFTAILAEHVGRAAGRPAAEGIDGEVVKPGHIYIAPGGKHMVLEKSGNDKVIRLHDGPPVNFCKPAVDPMFDTVSEIYGRNALAVVLTGMGSDGAKGAGRIADAGGSVIAQDEETSVVWGMPGATVQMGNASEVLSIADIGRKVSRLLTGGRA</sequence>
</entry>
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        <name evidence="2" type="ordered locus">AZC_0670</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0670"/>
    <dbReference type="EnsemblBacteria" id="BAF86668">
        <property type="protein sequence ID" value="BAF86668"/>
        <property type="gene ID" value="AZC_0670"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0670"/>
    <dbReference type="eggNOG" id="COG3729">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2271618_0_0_5"/>
    <dbReference type="OMA" id="EAFMANN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019626">
        <property type="entry name" value="Stress-induced_KGG_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10685">
        <property type="entry name" value="KGG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="102" mass="10692" checksum="DC829B774D687BCB" modified="2007-12-04" version="1">MAGEHQRREAFMANNQQGGSGNFANDREKASEAGRKGGQSTQQHSQSSGNMGQQGGSGNFAQNPERAAEAGRKGGQSVPDEKRSFSQDHDLASEAGRKGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQF4</accession>
    <name>A8HQF4_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1033</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1033"/>
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        <property type="gene ID" value="AZC_1033"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1033"/>
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    <dbReference type="GO" id="GO:0043565">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="DUF1153"/>
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    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="91" mass="10403" checksum="F6E670C97576C77A" modified="2007-12-04" version="1">MTDAYRPRVKYVIGPDGSPLTIADLPPPDTRRWVIRRKAEVVAAVRGGLISLEEACKRYTLTVDEFLSWQASIDRHGLPGLRTTRIQHYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
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        <name evidence="1" type="ordered locus">AZC_1118</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169649.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1118"/>
    <dbReference type="EnsemblBacteria" id="BAF87116">
        <property type="protein sequence ID" value="BAF87116"/>
        <property type="gene ID" value="AZC_1118"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1118"/>
    <dbReference type="eggNOG" id="COG5437">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_151316_0_0_5"/>
    <dbReference type="OMA" id="FAGEHNG"/>
    <dbReference type="OrthoDB" id="1555559at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022344">
        <property type="entry name" value="GTA_major-tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011855">
        <property type="entry name" value="Phgtail_TP901_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06199">
        <property type="entry name" value="Phage_tail_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01996">
        <property type="entry name" value="MTP1FAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02126">
        <property type="entry name" value="phgtail_TP901_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="135" mass="14060" checksum="5444381DE6F9EBBF" modified="2007-12-04" version="1">MAAQMGKDLLLKMLDGADYVTVAGLRSRTLAFNAQTVDVTHSESAGRWRELLAGAGVKRASISGAGIFKDAASDALVRAAFFAGEVRDCAVVIPDFGTVSGPFLISALEIAGQHDREVTFDLTLESAGALAFAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8HR51</accession>
    <name>A8HR51_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1120</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1120"/>
    <dbReference type="EnsemblBacteria" id="BAF87118">
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        <property type="gene ID" value="AZC_1120"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1120"/>
    <dbReference type="HOGENOM" id="CLU_188457_1_1_5"/>
    <dbReference type="OMA" id="QFWRMTP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="InterPro" id="IPR019056">
        <property type="entry name" value="Phage_TAC_6"/>
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    <dbReference type="Pfam" id="PF09550">
        <property type="entry name" value="Phage_TAC_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="55" mass="5937" checksum="659C949D7214D94B" modified="2007-12-04" version="1">MALGFGILRLSSRDFWCLTPRELAAACRPPAATSSGLDRAGLAALMARFPDTTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRD2</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein</fullName>
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        <name evidence="3" type="ordered locus">AZC_1168</name>
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    <organism evidence="3 4">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172624.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4104"/>
    <dbReference type="EnsemblBacteria" id="BAF90102">
        <property type="protein sequence ID" value="BAF90102"/>
        <property type="gene ID" value="AZC_4104"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4104"/>
    <dbReference type="eggNOG" id="COG4177">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031365_0_0_5"/>
    <dbReference type="OMA" id="FKIFAFC"/>
    <dbReference type="OrthoDB" id="1425262at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017778">
        <property type="entry name" value="ABC_transptr_urea_perm_UrtC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482:SF4">
        <property type="entry name" value="PTHR30482:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03408">
        <property type="entry name" value="urea_trans_UrtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="371" mass="40111" checksum="44D56FDE34BA98F1" modified="2007-12-04" version="1">MSFSLRSKDLLGVLLLAVLLVVVLPLVLEPFRLNMVGKYLTYAFVAVGLVLCWGNAGILSLGQGVFFGLGGYCMAMYLKLEASTPEATKIQSTPGIPDFMDWNQLTSLPFFWVPFKSLGFSVIAVMLVPAVFALVLAFALFKRRVGGVYFAIITQALAAIMSILIIGQQGYTGGVNGITDLRTLHGWDIRTDSAKFILYFVNVGLLIGVILLCQFVQRSKLGRILVAMRDKEDRVRFSGYDVASFKIFVFCFAAALAGIGGAMFTLQVGFMSPSFVGITPSIEMVIYTAVGGRLSLLGAVYGTLLVNWAKTSFSESFPELWLFGLGGLFIAVVLLFPNGLAGLYRTYVEPRLGALLGRKGAEPKAAPAPAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-10-13" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS51</accession>
    <name>OBG_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GTPase Obg</fullName>
            <ecNumber evidence="1">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">obg</name>
        <name type="ordered locus">AZC_4141</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172661.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HS51"/>
    <dbReference type="SMR" id="A8HS51"/>
    <dbReference type="STRING" id="438753.AZC_4141"/>
    <dbReference type="EnsemblBacteria" id="BAF90139">
        <property type="protein sequence ID" value="BAF90139"/>
        <property type="gene ID" value="AZC_4141"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4141"/>
    <dbReference type="eggNOG" id="COG0536">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011747_2_0_5"/>
    <dbReference type="OMA" id="VFMVDIF"/>
    <dbReference type="OrthoDB" id="603226at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000385711" description="GTPase Obg">
        <location>
            <begin position="1"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Obg" evidence="2">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="1">
        <location>
            <begin position="160"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="166"/>
            <end position="173"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="191"/>
            <end position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="212"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="279"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="308"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01231"/>
        </source>
    </evidence>
    <sequence length="345" mass="37169" checksum="6ADC3702FF1F8AD0" modified="2007-12-04" version="1">MKFLDQAKVYVRSGDGGAGCVSFRREKFIEFGGPDGGNGGRGGDVWIECVDGLNTLIDYRYQQHFKAKKGEHGMGANRAGAKGSDVVLRVPAGTQVLDEDEETILADLTEVGQRIRLLSGGNGGFGNAEFKTSTNQAPRRANPGLEGQEKWIWLRLKLIADAGLVGLPNAGKSTFLAATTAAKPKIADYPFTTLHPGLGVVRVDGREFVLADIPGLIEGAHEGAGLGDRFLGHVERCRVLLHLVDGTCEHAGKAYKTVRQELVAYGGGLEDRVEIVALSKIDSLTPELLKQQKERLQRAAKKKPLLLSSQSGKGVPEALRALLAVIDEGREAEVAEARKTEWRPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT23</accession>
    <name>A8HT23_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gcvH</name>
        <name evidence="6" type="ordered locus">AZC_4246</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
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        <location>
            <begin position="18"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
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    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90244.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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    </evidence>
    <sequence length="123" mass="13318" checksum="3C37B4816812193B" modified="2007-12-04" version="1">MTTRYSKDHEYVRLEGDVAVVGISNYAQEQLGDVVFVELPEIGKAIAQGKEAAVVESVKAASEVYAPVSGEVVEVNSDLEATPATVNEDPEGKGWFLKLKLSDTAQFDALMSADDYKAYLDTL</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
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    </evidence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0825"/>
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    <dbReference type="OrthoDB" id="2063193at2"/>
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        <property type="component" value="Chromosome"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="97" mass="10535" checksum="3149F76A3402FCBA" modified="2007-12-04" version="1">MNTANLQLEGLLLAVSNLIEMLRRKGLVTQQEIEEALHEALGAARRDADGRNISPAQGAGMEFPIRFLLTATNLSDGPPQTFSEVAAMIGETRDQDK</sequence>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF86858.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="126" mass="13882" checksum="7966B98B3928BC6D" modified="2007-12-04" version="1">MWVEGIMVEQGATEDSMTKPRFIWAFDFGQVMQTLATVIPIASLVWYMAASNAEMRRDIATLQAREASYAPKVDALAKSNDVQDERIGNIADAVRGIQRVNAEMLSQIGGVREDLAGIKARIAVPR</sequence>
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            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169417.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HTY4"/>
    <dbReference type="SMR" id="A8HTY4"/>
    <dbReference type="STRING" id="438753.AZC_0886"/>
    <dbReference type="EnsemblBacteria" id="BAF86884">
        <property type="protein sequence ID" value="BAF86884"/>
        <property type="gene ID" value="AZC_0886"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0886"/>
    <dbReference type="eggNOG" id="COG0222">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086499_3_0_5"/>
    <dbReference type="OMA" id="LEDKWGV"/>
    <dbReference type="OrthoDB" id="1822695at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000072111" description="50S ribosomal protein L7/L12">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <sequence length="125" mass="12817" checksum="30951B9BDD85FC3A" modified="2007-12-04" version="1">MADLTKLVDELSSLTVLEAAELAKLLEEKWGVSAAAAVAVAAAPAAGGAAAAVEEQTEFTVVLANAGDKKIEVIKEVRAITGLGLKEAKDLVEGAPKPVKEGVAKDEAEKLKAQLEKAGAKVELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUH9</accession>
    <name>A8HUH9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane autotransporter barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0948</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0948"/>
    <dbReference type="EnsemblBacteria" id="BAF86946">
        <property type="protein sequence ID" value="BAF86946"/>
        <property type="gene ID" value="AZC_0948"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0948"/>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_301623_0_0_5"/>
    <dbReference type="OMA" id="RFENSGW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721183" evidence="1">
        <location>
            <begin position="39"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="2">
        <location>
            <begin position="711"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="990" mass="100424" checksum="E3D370374152B9E5" modified="2007-12-04" version="1">MGREWGMSRFLTYRRMARSSLKPALLAGVAMWCTVAGAQAQSAPTIYQTLNYGTSGTFLTGIRGNTIVGNYVVPGTGATGGLLYDMTTGAWSAFPVATSNGVNYPNATGSSPYGPSFGSQTGILRTVGSYITSASAPYDLGYLYDAAAAPARQLTTLAYPSASGNPTLYTIAHSTFGDTVVGNFDTRLATGNAVIYTISTGTYVKNNMPGAVSTTAYGVYGDMIAGGYANAGPGGGIGFEHGYLYNTLTGTWTTYDHPGAIITHLEGITGAGRSGEYNMVADWVTPDNVVHAGVLHVDALGIPTWYELNIPGALLVSSNSAYGDKVVGIYLTPGSATPNGYIATLPGIYNPIRNTGTLTSSADNAAALSGAKGDDIVNSGTVRVSGTGGIGMRGETYGVLTNMGTVVASGVVGAAAELHGLYGTLLNYGTLQAPAVADALRTGPDAVGTAIVNYGVIDGRLAATGGLDKRLENSGWIGVSGIGVSITSLFGGTFVQTAAGTLSLRVTSSGTDTLSIVGVARLAGTLAVPFQTTSLTRNYTLFTSTQGYTGTFTNLVTSGLPSFMGASLVYAPNAVSLNLTSGMAQIQGLSTNQRAVGAGLDRAFNAGSGVSDPLTSLYALNSSQLPQALSALSGEALASEQSVLIGDGLYSRQAVLDRLRQGAYADRSGAMAALAYGGPTMSYAGSEASAPATSAAAALAYAAGGAPVAVPPPAGPTLWAQGFGSWANYGGNGNVSGISETLGGVISGIDATVGNWRVGGALGYTQSNASLNNVSGSSEADSATIALYAGTSAGPWNLRLGASYAFSQIDTTRTVAFPGFIEQAKANYNGGTGQLFAEVGYGFAVQAVAFEPYAGLAWVHLNTDSFSENGAVSSALSGASSSANVGYGTLGLRAATSLPLSNGMAFAPHVSAAWQYAFGDLTPSAQLALASVPGANFTVQGLPLAQNTALVEAGLDLKLNAQMRVGASYVGQFADSVTVNAFQANFTWNF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUR7</accession>
    <name>GLMM_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="1">5.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glmM</name>
        <name type="ordered locus">AZC_0975</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23424"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="EC" id="5.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="1">Activated by phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="EnsemblBacteria" id="BAF86973">
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    <dbReference type="eggNOG" id="COG1109">
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    <dbReference type="HOGENOM" id="CLU_016950_7_0_5"/>
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    <dbReference type="OrthoDB" id="1265792at2"/>
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        <property type="entry name" value="GlmM_bact"/>
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    <dbReference type="Pfam" id="PF02878">
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    </dbReference>
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    <dbReference type="Pfam" id="PF00408">
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        <property type="entry name" value="PGMPMM"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01455">
        <property type="entry name" value="glmM"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0597">Phosphoprotein</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000073569" description="Phosphoglucosamine mutase">
        <location>
            <begin position="1"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" description="via phosphate group" evidence="1">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
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    <feature type="binding site" evidence="1">
        <location>
            <position position="246"/>
        </location>
        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphoserine" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01554"/>
        </source>
    </evidence>
    <sequence length="447" mass="48485" checksum="7750C3E539B19C1A" modified="2007-12-04" version="1">MARKYFGTDGVRGRANATLTADLALRVGMAAGLAFRRGEHRHRVVIGKDTRLSGYMIENALVAGFTSVGMDVLLLGPMPTPAVGMLTRSMRADLGVMISASHNPFDDNGIKLFGPDGFKLSDQIEHEIEELIDEDLSKKLAQPMDIGRARRVEGVHARYIEYAKRTLPRDQSFEGLRVVVDCANGAAYRVAPDALWELGAEVISMGVEPDGLNINRDVGSTSPAALSAKVREVRADVGIALDGDADRVIIVDEKGHVVDGDQIMAVVAHSFKEDGRLSRDGIVATVMSNLGLERYLKDEGLTLARTSVGDRYVLERMRSDGYNVGGEQSGHIILSDYSTTGDGLLAALQVLAVVARSERPVSEVCHRFDPLPQVLKNVRYSSGKPLEHENVQSAIADAERRLANHGRLLIRPSGTEPVIRVMGEGDDFELVEGVVDEVIEALRKVAA</sequence>
</entry>
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    <accession>A8HUS1</accession>
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        <submittedName>
            <fullName evidence="4">Putative cabohydrate kinase</fullName>
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        <name evidence="4" type="ordered locus">AZC_0976</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0976"/>
    <dbReference type="EnsemblBacteria" id="BAF86974">
        <property type="protein sequence ID" value="BAF86974"/>
        <property type="gene ID" value="AZC_0976"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0976"/>
    <dbReference type="eggNOG" id="COG0524">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027634_5_1_5"/>
    <dbReference type="OMA" id="APFIAQF"/>
    <dbReference type="OrthoDB" id="1604782at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="59"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="333" mass="34519" checksum="BA84289C13AB8DA0" modified="2007-12-04" version="1">MSSHTLDVLAIGNAIVDVIARADEAFLADHGMPKGSMSLIDEARAEQLYGAMGPGIEISGGSAANTAAGAASLGARAGFIGKVREDGLGKTFAHDIRAAGVAYGTPAANEGPATARCLILVTPDGERTMNTYLGAAQNLTTADIDAASVESAAVTYLEGYLWDPPAAKEAFLAAAKISHTAGRQVALTLSDAFCVDRYRAEFLDLMRNGTVDLVFCNEGELKSLYETADVDSALVQLRRDVASAVVTRSERGALFVAKDAVVSAPAHAVAQVVDTTGAGDLFAAGFLTGYTRGLDPATSLRIGALAASEIISHMGARPERNLLDYARETGLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWE1</accession>
    <name>A8HWE1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4421</name>
    </gene>
    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
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            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
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            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
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        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF87428.1"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="eggNOG" id="COG2896">
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    <dbReference type="OMA" id="FRHMSVT"/>
    <dbReference type="OrthoDB" id="1199289at2"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Mob_synth_C"/>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
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            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="18"/>
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        <ligand>
            <name>GTP</name>
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        </ligand>
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            <position position="25"/>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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            <note>4Fe-4S-S-AdoMet</note>
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    <feature type="binding site" evidence="12">
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            <position position="29"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        <location>
            <position position="31"/>
        </location>
        <ligand>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        <location>
            <position position="67"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:59789"/>
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        <ligand>
            <name>GTP</name>
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            <position position="125"/>
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        <ligand>
            <name>S-adenosyl-L-methionine</name>
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        <ligand>
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        <ligand>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
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        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
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        <ligand>
            <name>GTP</name>
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        <ligand>
            <name>[4Fe-4S] cluster</name>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    <sequence length="333" mass="36149" checksum="DC78B3BDB14EFD0A" modified="2007-12-04" version="1">MTRCGLVDLFGRRVSYLRLSVTDRCDLRCVYCMAEDMAFVPRNQLLTLEELDRLASAFVARGVAKIRLTGGEPLVRKGLMELVSSLSRHLAARRLKELTLTTNGSLLARHADGLARAGVRRVNVSLDTLDASRFRALTRRGTLGVVMEGLLAAQEAGLKVKLNAVALKGSTEDEIHDLIAFAHGRGMDLTLIETMPLGDVGADRTDQYLSLATLRRTIETRWTLTDTADRSGGPARYARVAETGGRIGFITPLTHSFCETCNRVRVSATGVLYTCLGQEDQVDLRAPLRACEGDEALHAAIDAGIRAKPRGHDFAIARNGAPALARHMSVLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX78</accession>
    <name>A8HX78_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="2" type="ordered locus">AZC_1470</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <property type="gene ID" value="AZC_1470"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="TrcR"/>
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        <property type="entry name" value="DUF1013"/>
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        <location>
            <begin position="177"/>
            <end position="214"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <sequence length="232" mass="25805" checksum="36A7DC70F237C930" modified="2007-12-04" version="1">MSNTPLMPKATAVWLVENTALTFEQIGDFCKLHPLEVKGIADGEVAQGIKGLDPIANGQLTREEIDKGEKNQNYHLKLQESKVRLPEPKRRKGPRYTPVSRRHDRPNAILWLLRNHPELKDAQIIRLVGTTKATIQSIKDRTHWNSAQLAPMDPVTLGLCSQIDLDLEVQRAAKDRPAALASEDRGATLLPADVTTQRHEDDAPSSGRKDSLDLETVFAKLGGARKSEDEED</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1525"/>
    <dbReference type="EnsemblBacteria" id="BAF87523">
        <property type="protein sequence ID" value="BAF87523"/>
        <property type="gene ID" value="AZC_1525"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1525"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094953_0_0_5"/>
    <dbReference type="OMA" id="VVPHLYA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="1">
        <location>
            <begin position="102"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="260" mass="29951" checksum="EF169EDCBFD0718D" modified="2007-12-04" version="1">MRAYKAARATHARMDHDWETRRCAAVRPVRERAMTDVRPDAPETAPDLPESKLTATKQKWAREGRFLTGRVARTGEDRLPPGQHLVKDWPVLDLGLQPEVPLNAWALDVDGLVAHPAHWDWSAFKAQPQSDLVTDIHCVTTWSRYDNRWDGLLTRDLMAMVEPLPSARFVVMHSYDGYTTNVPIEDFAAEDALLAHSWEGQPLTRAHGGPVRVVIPHLYFWKSAKWVKRIEFIPADRLGFWEVRGYHERGDPWTEQRYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXP9</accession>
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        <alternativeName>
            <fullName evidence="9">Sedoheptulose 7-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmhA</name>
        <name evidence="11" type="ordered locus">AZC_1526</name>
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    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>2 D-sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27489"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:60203"/>
            <dbReference type="ChEBI" id="CHEBI:60204"/>
            <dbReference type="EC" id="5.3.1.28"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Carbohydrate biosynthesis; D-glycero-D-manno-heptose 7-phosphate biosynthesis; D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    </reference>
    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <location>
            <begin position="1"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="315" mass="34828" checksum="F010FED5327BD39A" modified="2007-12-04" version="1">MSTVHRHKNAASVTSLRSDDPERDVVRKRIAALRLHPEIGQVSRQMASSLVRRYEGNRIANRVLNDRARAIFAIMVLYLHTNPDASGTRLTAGRIIGLCQETGMCSRGRAKAMLLLMRWAGYIEPTPDLPSDADRRQRPLSPTQALLDDYTARWSDVFGSIALVDEIGVQALARIEEPEFRAGLSEALMRRFRAGWRVLDFTPPLELFAARDCGFVMLLALTLSAPEGSPFPPSGPLKIPVAALGRRFHVSRAHVLKMLRDAEAEGLLRRVSDGDGATVELQAPVRSALTDFFCAIFLLFGDAGREALARMTPKS</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY45</accession>
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    <reference evidence="3 4" key="1">
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <dbReference type="PROSITE" id="PS50943"/>
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    <sequence length="101" mass="11411" checksum="A846A541CD212525" modified="2007-12-04" version="1">MPADEQKPLAPVHPGEILREEFLQPLGLTPYALGGALRVPRTRIERLVRGETSLTADTALRLARYFGTTPDFWLRLQTAHDLRVEERRIAAELERIAPRAA</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8I086</accession>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1230"/>
    <dbReference type="EnsemblBacteria" id="BAF87228">
        <property type="protein sequence ID" value="BAF87228"/>
        <property type="gene ID" value="AZC_1230"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1230"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTHLYSR"/>
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        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87228.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="321" mass="34659" checksum="CE06CFFEC7D3727E" modified="2007-12-04" version="1">MALQPRSVPVSWLNPRQIEAFRAIMVSGTVTDAAALMGVTQPAVSRMLRDLQATLGLTLFERRGAKLVPTNEGLTVYAEVARSFVGLERIAHVAREVKERRAGVLRIAAMPALMNGFLPRFVGRFLKDKPRMDLSLSGVSSHLVLEHTLSGECDLGFVMGPLAHAGLIAHPMPSAPMVAVLPQHHPLAAKDAIHVTDFDGQDFIAMEPGGLSRMQLDRIMELHNVRPAVRAETRLSGIVCGLVTSGLGVSVCDPFTAHEFTARGLVIRPFTPSVDFEFAAVRSAQKRFPAVGKALLDAFVLHSRAFIAEAPWTQPEPAAAG</sequence>
</entry>
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            <fullName evidence="1">2Fe-2S ferredoxin-type domain-containing protein</fullName>
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        <name evidence="2" type="ordered locus">AZC_1282</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1282"/>
    <dbReference type="EnsemblBacteria" id="BAF87280">
        <property type="protein sequence ID" value="BAF87280"/>
        <property type="gene ID" value="AZC_1282"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1282"/>
    <dbReference type="eggNOG" id="COG1018">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_2010566_0_0_5"/>
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        <property type="component" value="Chromosome"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="fer2"/>
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    <dbReference type="Gene3D" id="3.10.20.30">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
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    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
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        <property type="entry name" value="Fer2"/>
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        <property type="entry name" value="2FE2S_FER_2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="42"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="123" mass="12922" checksum="CE7BB8B1C69DAF09" modified="2007-12-04" version="1">MDAVKAALHQLGVPNSQVKTEGFGTDRRDPSKKAQKLGKVIATVSFRESHLSAAAREGMTLLDVADESGVFIDSACRSGTCGVKLTSGKVRLGTDDALSDEERAQGYILACQAQPDGDVALDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0S2</accession>
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        <submittedName>
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        <submittedName>
            <fullName evidence="4">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0217</name>
        <name evidence="4" type="ordered locus">AZC_1290</name>
        <name evidence="5" type="ordered locus">AZC_1931</name>
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    <organism evidence="4 6">
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="4 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="4">ORS 571</strain>
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    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="4">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="4">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="4">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="4">ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0217"/>
    <dbReference type="EnsemblBacteria" id="BAF86215">
        <property type="protein sequence ID" value="BAF86215"/>
        <property type="gene ID" value="AZC_0217"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87288">
        <property type="protein sequence ID" value="BAF87288"/>
        <property type="gene ID" value="AZC_1290"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87929">
        <property type="protein sequence ID" value="BAF87929"/>
        <property type="gene ID" value="AZC_1931"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0217"/>
    <dbReference type="KEGG" id="azc:AZC_1290"/>
    <dbReference type="KEGG" id="azc:AZC_1931"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_31_0_5"/>
    <dbReference type="OMA" id="RMTAQLN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="102"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="277" mass="31589" checksum="2676CAB35188A120" modified="2007-12-04" version="1">MAKLGVSERLACRVLGQHRSTQRKVPVGRADEAGLTADIIELATRYGRYGYRRITALLQASGWVVNVKRVERIWRREGLKVPSKQPKKGRLWFNGGSCLRLRPEHPNHVWSYDFVEDRTHNGRKFRMLNVIDEFTRECLAIRIDRKLNSTAVIDVLTDLFVLRGVPSHIRSDNGPEFIAKAVRDWITAVGARTAFIAPGSPWENGYCESFNSKLRDELLDGEIFYSLAEARIVIEDWRRHYNTERPHSALGYKPPAPAVIVPQVPPTSNAPNRPTMH</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-11-03" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0Y1</accession>
    <name>DABA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable inorganic carbon transporter subunit DabA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dabA</name>
        <name type="ordered locus">AZC_1310</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of an energy-coupled inorganic carbon pump.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with DabB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169838.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I0Y1"/>
    <dbReference type="STRING" id="438753.AZC_1310"/>
    <dbReference type="EnsemblBacteria" id="BAF87308">
        <property type="protein sequence ID" value="BAF87308"/>
        <property type="gene ID" value="AZC_1310"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1310"/>
    <dbReference type="eggNOG" id="COG3002">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009885_1_0_5"/>
    <dbReference type="OMA" id="DCDLEGR"/>
    <dbReference type="OrthoDB" id="179501at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01871">
        <property type="entry name" value="DabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018752">
        <property type="entry name" value="DabA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38344">
        <property type="entry name" value="PTHR38344"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10070">
        <property type="entry name" value="MpsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_0000387232" description="Probable inorganic carbon transporter subunit DabA">
        <location>
            <begin position="1"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="498"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01871"/>
        </source>
    </evidence>
    <sequence length="811" mass="87658" checksum="6D543DB3390ADE01" modified="2007-12-04" version="1">MLMTTPGSPLPSPDVLLEAANRAARAIPPLWPLASSVAVNPFLGQTGEPLATAASRLRRVAGIPLTMPRSWYADRLRSGEIAEEDLRAAFESAPAALRPKTFASLKRAVQSERPEPHAIPTLADLARDVAGIDWPAIVNDRISHWASSYFDEGQALWAKGQQGAAYSAWRIIATHDLTPEIAGLEGFAQSVADAPANAEDAIIACVARLGLCGPALESYFHRLLTTLGGWSQLARYRLWQAELTGNTDASVTDLLTIRLIWEAALLRKFGPVVEAQWKAAIAAYAEPVSATPEDVVDAILQEAAERAAQWRLGACLTGTSPARVADGRPTLQMAFCIDVRSEVFRRALESLDPGIRTLGFAGFFGLGIGHRRFGSDVVEARLPVLLKPGIFTCSGEATPAVTSSDLAARITARVERAWGRFKLAAISSFAFVEAAGPIYVAKLLRDGLGLKRHAAPNDPAPRPTSALDLDTRLTMAVSILKAMSLTRGFARLVLLAGHGANVVNNPHASALHCGACGGYSGEVNARLLASVLNDREVRADLAERGIIVPEDTLFLAALHDTTTDDVNIYAADHASAAHAEDVDQAERWLKSAGILARGERALRLPRAKQGQDIPHRARDWAELRPEWALAGCQAFIAAPRARTAGHDLAGRAFLHDYDWRRDDGFGVLELILTAPVVVASWISLQYYGSTVAPDVFGAGNKLLHNVTGGIGVVEGNGGLLRAGLPWQSVHDGERLTHEPLRLSVLIEAPREAIARILERHPEVRALFDNLWLHLFALDDKGRMAWRYTGDLQWETCVGDEHADEHSVREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I168</accession>
    <name>A8I168_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_1340</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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                <person name="Vereecke D."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Ussery D.W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <location>
            <begin position="101"/>
            <end position="122"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87340.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="135" mass="13935" checksum="B7C65496CF455B19" modified="2007-12-04" version="1">MLAYGYVALGGALGSILRFGMNRWLTLLLGDGLPWGTILINIGGSFVIGLCAALFENGPGASTPLEVRQFVLVGLCGGFTTFSSFSLQTLTLLHAGEPGRALLNVMLSLALCLAAVAVGYMLPGSIATWSRSVGA</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169889.1">
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    <dbReference type="STRING" id="438753.AZC_1361"/>
    <dbReference type="EnsemblBacteria" id="BAF87359">
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        <property type="gene ID" value="AZC_1361"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <location>
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        </location>
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    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
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    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF87359.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="218" mass="23721" checksum="E7876EF4042944E3" modified="2007-12-04" version="1">MISRTQGRSPTPTQGPVVIVVDDDADLRDALTSLFRSIGLEVVSFGSAPELLAAKLPDTPRCLVLDIRLPGVSGLDFQSQLQRSDLDLPIIFMTGHGDIPMTVRAMKAGAVDFLTKPFRDQDMLDAVSAAIEIDRTRRAEREAASHLRALYATLTERERQIMALVTSGLMNKQVAGEVGLSEITVKIHRGNVMRKMEAQSLADLVRMAEALGIRAAKG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169950.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1422"/>
    <dbReference type="EnsemblBacteria" id="BAF87420">
        <property type="protein sequence ID" value="BAF87420"/>
        <property type="gene ID" value="AZC_1422"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1422"/>
    <dbReference type="eggNOG" id="COG3865">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_046006_22_0_5"/>
    <dbReference type="OMA" id="DQDEVDY"/>
    <dbReference type="OrthoDB" id="1889762at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:methylation"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
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        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
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    </dbReference>
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        <property type="entry name" value="3_dmu_93_MTrfase"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="159" mass="17235" checksum="01B018A886A775C8" modified="2007-12-04" version="1">MTSPKNMICLWYERDAEAAARFYAQTFPDSAVKAVYRAPTDYPAGKAGDVITVEFTVAGLPCLGLNGGPVFRHNEAFSFQIATDDQAETDRYWDAIVGNGGQEGACGWCKDRWGISWQITPRVLTQAVAAGGEEAKRAFTAMMQMKKIDIAAIVAACKG</sequence>
</entry>
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    <accession>A8I229</accession>
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        <submittedName>
            <fullName evidence="4">Histidine kinase A</fullName>
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        <name evidence="4" type="ordered locus">AZC_4692</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4692"/>
    <dbReference type="EnsemblBacteria" id="BAF90690">
        <property type="protein sequence ID" value="BAF90690"/>
        <property type="gene ID" value="AZC_4692"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4692"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046130_1_1_5"/>
    <dbReference type="OMA" id="LNRWHLM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="235"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="458"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF90690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="473" mass="50950" checksum="081407B1019BBC9A" modified="2007-12-04" version="1">MDQNFLVRGWSAARLSENLSVMASPFTPPARSLGLRLDTLIRLRWLAVAGQTLALLVVYLLMAFPVPLAACLAPVALSVLLNIVLRARYPGATRLPDLTAGPLLAYDVLQLTALLYLTGGLSNPFAFLYLAPVMISATALSWRTTATLGAFVVFCAGAVGLFHWPLPWASVGAPVLPDLYLAGLWVALTVSVAFIGLHSWRVAEEARELADALAATELVLAREQHLSQLDGLAAAAAHELGTPLATIALVVKELEHSVPKNDPHAEDIALLRDQVKRCRDILQKLTSLGSGDAPFDRMPLRLLIEEVVEPHRDFGIEIAISLPEDPAGEPVLARNPGLIYGIGNLVENAVDFAAHRVDITGRWTPTHMELVVRDDGPGFAPEVSDRIGLPYVTSRARTPEDATGESGLGLGFFIAKTLLERSGANLKVENRAAPEHGATVRIIWPRSALDLEESETDLASNQRTMSPEVTKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8I317</accession>
    <name>A8I317_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">ABC transporter permease protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1970</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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            <taxon>Proteobacteria</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ornithine cyclodeaminase/mu-crystallin family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="BAF88008"/>
        <property type="gene ID" value="AZC_2010"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2010"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="entry name" value="ODC_Mu_crystall"/>
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        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF51735"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88008.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="334" mass="34848" checksum="C4A9192F6347C00B" modified="2007-12-04" version="1">MLWIAHGMPFMPRRRDRCEELDMFRVFDAAQIHAALEYRALIEALRAAFAEAATETPVRQSYEVGLPGAPAHLLTMPAWRRGNVLGVKLVNVFPGNSALGLGAVNGLYVLFDGATGVPKAIMDSDALTNRRTAAASALASGFLSRPDSRTLLVVGTGHLSAHLAAAHCAVRPISRVLVWGRSPDKAEKAAAKLTAQGQPAEPVTDLAAATAEADIITSATTSTVPLIAGRNVRPGTHVDLVGAFTPAMRESDDDLIAGASVYVDTRAGALAEAGDLLQPIAAGVFAKDRVKGDLYELCGGRAAGRSSDSEITVFKSVGAAIEDLVAAQMVSGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="14"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
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    </evidence>
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    </evidence>
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            <dbReference type="SMART" id="SM00825"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88404.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
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    </evidence>
    <sequence length="426" mass="44983" checksum="F6F6F89059389287" modified="2007-12-04" version="1">MAQTYNDKFGRPIVVVTGIGIVTSLGQGKAENWKKLTAGESGIHRITRFPVEGMRTTIAGTVDFLFDERVAAPNLSEKLATLAAEEAISEAGIGGNGDFPGPLFAAVPPVEIEWPERRQLAEVVTHRPMVYHDLLGAAATGKFRPWHERFLFGSVADALADRFGTRGQPISLSTACASGATAIQLAVEAIRRGECDVALSLGTDGSVHPEALIRFSLLSALTTANDNPAEASKPFAKNRDGFVMAEGAAALVLESYEHAKARGARILGVLEGAGEMADNFHRTRSSPDAKPIIGCINRALSDAGVTIADVGYINAHGTSTPENDRMEHVGFSAVFGEQLKNVPISSNKSMIGHTLTAAGAIEAAFSLLTIQNSRIPPTINYHVPDPAIPLDVVPNVARDAEVKRVISSSFGFGGQNVCLVIAGEPA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="KEGG" id="azc:AZC_2437"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="260" mass="29286" checksum="733086BB4EFCCE30" modified="2007-12-04" version="1">MMPPASALYSGTVVHHRVRPRAHRLSYKMFSLLLDLDELDALDGRLRLFSRNRFNVFGFRDRDYGDGSRTPLRVQVERHLAAAGIAFDGGPIRLLTMPRILGYAFNPLSVYFCYRRDGGLAAILYEVNNTFGERHSYLLPTDDPFAPTIRQRTDKRFFVSPFMDMDLTYQFRVQPPGARVGIGIATRDRSGLVLSATLASTRVELTDNALLNAFFSCPLLTLKVIGGIHWEALQIFLKGIGLRHRPPPPVHPVTVARSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8I798</accession>
    <name>A8I798_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Putative autotransporter</fullName>
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    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2096</name>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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    <dbReference type="STRING" id="438753.AZC_2714"/>
    <dbReference type="EnsemblBacteria" id="BAF88712">
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    <sequence length="333" mass="35824" checksum="E2F03D5179C8318F" modified="2007-12-04" version="1">MFKKGLAASLIAAVLGTSAPAFAEGTIRIVEQFGTLYTPFHVMKAQKLIEKHGQALGLDIKVDWAKLSGGSAVNDALLSGNVDVAAAGIGPFLTLWDRTRGSANEVKIIGALGAQPNYLVTNNPNVKTLKDFTKADKIALPAVGVSVQARILQMAAQQAFGPGKEKSLDDLTITLPHPDATAALLSGSTEITAHVSNQPYQDQALKDPKVHKVFSSYDVLGGPVTPTFVYSTVRFKTQNPKTYKAFFDAFREATAWVDAHKAEAAAIYVKTENSKLDPAFVTEVLSDPQVKYTLTPLGSQKFADFLAQIGAIKNRPASWKDYTFDDLHNDQGS</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="9 10" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="7Fe_ferredoxin"/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dGTPase family. Type 2 subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171331.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I9M0"/>
    <dbReference type="SMR" id="A8I9M0"/>
    <dbReference type="STRING" id="438753.AZC_2807"/>
    <dbReference type="EnsemblBacteria" id="BAF88805">
        <property type="protein sequence ID" value="BAF88805"/>
        <property type="gene ID" value="AZC_2807"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2807"/>
    <dbReference type="eggNOG" id="COG0232">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028163_1_0_5"/>
    <dbReference type="OMA" id="HCKAFRR"/>
    <dbReference type="OrthoDB" id="370035at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016793">
        <property type="term" value="F:triphosphoric monoester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01212">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006261">
        <property type="entry name" value="dNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023023">
        <property type="entry name" value="dNTPase_2"/>
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    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01353">
        <property type="entry name" value="dGTP_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000073112" description="Deoxyguanosinetriphosphate triphosphohydrolase-like protein">
        <location>
            <begin position="1"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="68"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01175"/>
        </source>
    </evidence>
    <sequence length="398" mass="44429" checksum="20435C23304C2AC4" modified="2007-12-04" version="1">MAVSGARPRMTWACDPVWTRGRLVPEQEGTRSAFRRDCDRIIHSTAFRRLKHKTQVFVFHEGDHYRTRLTHTLEVAQIARSIARALGLDEDLAEALALAHDLGHPPFAHAGERALDACMADYGGFDHNAQSLRVVTRLERRYAGFDGLNLTWETLEGIAKHNGPLTDRSGKPLGAAGDVLPHAIVAHSAVQDLELWTHAGPEAQVAAISDDIAYDVHDLDDGLRAGLFHLDELEALPLVGAVLAEVRASWPSLETGRVIHEVMRRLITRFVEDVVRETETRARAAKVRSSFDVRMAGAPLVAFSAGMRTAEAAVKGFLFPHMYRHARVNRIMDEAQGVVRDLFALFMARPQEMPADWQLEGAPPERMARRVADYIAGMTDRYALDQHARFFDTTPELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9Y8</accession>
    <name>A8I9Y8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Abhydrolase 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170967.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2441"/>
    <dbReference type="EnsemblBacteria" id="BAF88439">
        <property type="protein sequence ID" value="BAF88439"/>
        <property type="gene ID" value="AZC_2441"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2441"/>
    <dbReference type="eggNOG" id="COG0596">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020336_50_1_5"/>
    <dbReference type="OMA" id="EDDHCLQ"/>
    <dbReference type="OrthoDB" id="1196738at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="21"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="292" mass="32285" checksum="65A2C8B3622DC4B2" modified="2007-12-04" version="1">MHVTTKDGIRLHVEEAGEGTPILFVHEFGGNHMSWEPQMRFFARRHRCITYAARGYAPSDIPSDMEQYSQALAADDAVAVLDGLGIGKAHIVGLSMGGFATVHFGLRTPERALSLTVAGAGYGCEKEFEEYFRGVSREVADNFERQGAKEFSKIYALGASRVQFQNKDPRGWKEFADRLATHSDLGAAMTMRGVQARRPSFWDLEEGLKSMNVPTLIMVGDEDDHCLQPGIFLKKTIPASGLCVFPKTGHTLNLEEPAAFNAQLAEFIAQVEAGRWLPRDPRAIPGQIMRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA15</accession>
    <name>A8IA15_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2451</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <authorList>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF88454">
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    <dbReference type="KEGG" id="azc:AZC_2456"/>
    <dbReference type="eggNOG" id="COG1176">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_016047_18_3_5"/>
    <dbReference type="OMA" id="HALIPFM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="64"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="285" mass="30771" checksum="C1E68D81FA9033E7" modified="2007-12-04" version="1">MALRTGRRIFWWGLIAPTFVLYALIFFVPLGILGSESLHAGAGGGLTSANYAAFFTDGVTLSIFWRTVRLSLLITAACILFGYPLALFMRRAGPVLRLVALTIVISPLLTSVVVRNVAWLLVLGREGMVNALLRQSGLIDGPLPLLYNTFGVVVGVTHVYLAFLVMPVFSSLLSIDPSVEDAAASLGASRTTVFWRVTFPLSLPGLIAGTTLVFVLSMGVYLTPVIMGGSFVTTLPMVMTDLVRNQFDWSRAAAFAIVLLAFILIVLGLSSRAEKRIERMRGEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA76</accession>
    <name>A8IA76_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">FAD dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2474</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171000.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2474"/>
    <dbReference type="EnsemblBacteria" id="BAF88472">
        <property type="protein sequence ID" value="BAF88472"/>
        <property type="gene ID" value="AZC_2474"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2474"/>
    <dbReference type="eggNOG" id="COG0277">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017779_4_1_5"/>
    <dbReference type="OMA" id="WHVLVEL"/>
    <dbReference type="OrthoDB" id="1034540at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="39"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="479" mass="50410" checksum="5C103E1231C34F2C" modified="2007-12-04" version="1">MASPSSDIVSALTALLGADSLLTEAADVAAHIEDWRERYRGPAACVVLPRSTQEVSDVVRLCHAHGVPVLPQGGNTSLCGGAVPGTDGQPPVIVALSRLRRIRSVDPANNAMVVDGGCVLANVQEAAREAGRLYPISLGAEGSCQIAGTIATNAGGTAVLRYGNTRENILGLEAVLPDGAIWDGLKALRKNNTGYDLKHLFIGSEGTLGIITGATLKLHPLPTAFCVAWVGVSSPDAALSLLGRLQSACGARLSAFELINDLQLDLVLANVPGRRNPFSASHPWHVLVELSDNSPEVELSAVLGRVLEEAMEADLIEDAVLAASEAQRAALWEIRHSVSEANKKAGVGLTTDCAVPVSAVPTFIAQATEAVRAIVPDLPVIVVAHMGDGNAHFIPFFTYPEWEAVADKEAMAHRMRHVVNEVSHALGGTFSAEHGVGRTHIAEMAHFKSPVELKLMHAVKAAFDPDNLFNPGRLLPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAN0</accession>
    <name>A8IAN0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Periplasmic serine endoprotease DegP-like</fullName>
            <ecNumber evidence="7">3.4.21.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2528</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.</text>
            <dbReference type="EC" id="3.4.21.107"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the peptidase S1C family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2528"/>
    <dbReference type="EnsemblBacteria" id="BAF88526">
        <property type="protein sequence ID" value="BAF88526"/>
        <property type="gene ID" value="AZC_2528"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2528"/>
    <dbReference type="eggNOG" id="COG0265">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020120_1_1_5"/>
    <dbReference type="OMA" id="EGKGPWP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011782">
        <property type="entry name" value="Pept_S1C_Do"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02037">
        <property type="entry name" value="degP_htrA_DO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="PDZ" evidence="8">
        <location>
            <begin position="276"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="8">
        <location>
            <begin position="408"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR611782-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="492" mass="50652" checksum="802C5BA99C601A4B" modified="2007-12-04" version="1">MGFAGVRSWVGAVLAGGLVVAGLSVAVAQQVERQAPAGPPAHAQAGTVVPSSAAAMKMSFAPVVARTAPAVVNVYALKIAQRTNPFIDDPFFRRFFGGGPGGGGLGAPERVQRSLGSGVIVDPSGLVVTNQHVIQGADQIRIALNDKREFDAEVLLSDQRTDLAVLRIKGEGAKFSSLEIGNSDELAVGDLVLAIGDPFGVGQTVTQGIVSALARTQVGVSDYQFFIQTDAAINPGNSGGALVDMDGRLVGINSAIYSRSGGSHGIGFAIPANMVKVVVASAKAGGKTVRRPWLGAKLQRVTPEIADSLGLQRPTGALVQSVATDGPAARAGLKTGDLIVAVEGQAIDDPESLNYRWGTRPLGGKANLGIVRQGRDQTLVVTLEPPPESVPRDEVVISSRSPFAGARVLNVSPAVADELRLDVDEGVVVISEVADGSPADAAGFRAGDIILEVNGGRIERTKDLVAATRTPSRAWKVTVARGGRTITAVLGG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-03-18" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAN5</accession>
    <name>RPOA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="1">RNAP subunit alpha</shortName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpoA</name>
        <name type="ordered locus">AZC_2530</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="1">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAN5"/>
    <dbReference type="SMR" id="A8IAN5"/>
    <dbReference type="STRING" id="438753.AZC_2530"/>
    <dbReference type="EnsemblBacteria" id="BAF88528">
        <property type="protein sequence ID" value="BAF88528"/>
        <property type="gene ID" value="AZC_2530"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2530"/>
    <dbReference type="eggNOG" id="COG0202">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053084_0_1_5"/>
    <dbReference type="OMA" id="LMKFRNF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0804">Transcription</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000323617" description="DNA-directed RNA polymerase subunit alpha">
        <location>
            <begin position="1"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="1">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="1">
        <location>
            <begin position="253"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <sequence length="341" mass="37819" checksum="FA4EBA858EDAD61B" modified="2007-12-04" version="1">MTQVIQKNWQELIKPEKLQVTAGADPKRLATVVAEPLERGFGMTLGNSLRRILLSSLQGAAVTSVHIDGVLHEFSSIPGVREDVTDIILNIKDIAIKMQGDGPKRLVAKKNGPGVLVAGDIQTVGDIQILNPHLVLCTLDEGAELRMEFTVDTGKGYVPAERNRPEDAPIGLIPIDSLYSPVRKVSYKVENTREGQILDYDKLTMQIETDGSVSAEDALAYAARILQDQLEIFVNFEEPKRESETAAIQELPFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKSETEMLRTPNFGRKSLNEIKEVLASMGLHLGMEVPGWPPENIEELAKRFEDHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB41</accession>
    <name>A8IB41_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ubiE</name>
        <name evidence="3" type="ordered locus">AZC_2606</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="4 5" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="296" mass="32813" checksum="717CFAA714857730" modified="2007-12-04" version="1">MGSTMPQPMPEASGWSARGQAEDSRETSQLGLTGGIVAQFDRRRDAEGWQEQLDTSRNLLTVALDEVGGATEVSLSPCRPTAQRVRPNHMSFLPAGTCAWESCSRISLYRRAVLAFDTETVSQIIGQPLSEPTEANVMFRDPRIWHCADLLARMSDGTDPGSQLYCDSLATALFVALFSPREPSTSGGLLPWQLRRVTDFIMDHLAEDIPLADLSALLGQSQSHFGREFRIATGMPPHKWQMNARVRRAQELMLDRHGSLADIAMEVGFADQSHFTRVFRAHTGLPPGQWKRAHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBX3</accession>
    <name>A8IBX3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3131</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171655.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3131"/>
    <dbReference type="EnsemblBacteria" id="BAF89129">
        <property type="protein sequence ID" value="BAF89129"/>
        <property type="gene ID" value="AZC_3131"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3131"/>
    <dbReference type="eggNOG" id="COG0625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011226_6_0_5"/>
    <dbReference type="OMA" id="TCLWESN"/>
    <dbReference type="OrthoDB" id="1752966at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="SSF47616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="3">
        <location>
            <begin position="84"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="221" mass="25108" checksum="966C6F7DAD040F80" modified="2007-12-04" version="1">MLTLYSTRSSGNAYKVRLLLAKLRLPFRLVEVDIFAGENRTPEFLQLNPEGRVPLLELEDGHILAESNAILFYLAEGTPFLPADPVARADTLRWMFFEQNNHEPGIAQARFWLRQVRGGRDLRAHDIDRWMEEGYGALRVMERHLVARSFFVGESLTIADIALYAHTHVAHEGDFDLAGFPNVRGWIDRMEAAPCHVDMDWSPEMPARLFAGDECGELSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="83" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBY5</accession>
    <name>A8IBY5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrP</name>
        <name evidence="7" type="ordered locus">AZC_3136</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Periplasm</location>
        </subcellularLocation>
        <text evidence="5">Is attached to the inner membrane when interacting with the MsrQ subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171660.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3136"/>
    <dbReference type="EnsemblBacteria" id="BAF89134">
        <property type="protein sequence ID" value="BAF89134"/>
        <property type="gene ID" value="AZC_3136"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3136"/>
    <dbReference type="eggNOG" id="COG2041">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045520_0_0_5"/>
    <dbReference type="OMA" id="WPYTEGL"/>
    <dbReference type="OrthoDB" id="1729032at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="6">
        <location>
            <begin position="101"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="237"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="320" mass="35939" checksum="799FB2C00BFAEEEF" modified="2007-12-04" version="1">MLIKSKRGWEIPEHLATPEGIFLSRRRLLGAGAGLIGASLLPGVAQAAETDPSASLYPAKRNERYTLDRPMTPEKDASSVNNYYEFGTNYDVGRAAAKLKVRPWTVTIDGMVEQPRQVGIDDLLKAMTLEERLYRHRCVEAWSMAVPWTGFPMKAFVDYARPLSGAKYVRMETFLDRDVAPGQSGRFYPWPYVEGLTMAEATNELAFLVTGVYGKPAQNQFGAPLRLATPWKYGFKSIKAIVKFTFTDQRPKSFWEVVQGAEYGFWANVNPQVSHPRWSQATEKDIATGERRPTLLYNGYGEFVAGLYGDPALKGEKLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC01</accession>
    <name>A8IC01_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3142</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3142"/>
    <dbReference type="EnsemblBacteria" id="BAF89140">
        <property type="protein sequence ID" value="BAF89140"/>
        <property type="gene ID" value="AZC_3142"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3142"/>
    <dbReference type="eggNOG" id="COG0161">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016922_4_1_5"/>
    <dbReference type="OMA" id="REGLNQH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="521" mass="55617" checksum="36B676BAAB419D2C" modified="2007-12-04" version="1">MLLFSAVPAGTPRGSMPGHACGSAEAGRQGRRAACLERGRTAGMVGQAQAVRGVPPVSVFANSTAHWRHLDAAHHLHPFSDTKGLNAEGVRVITRAEGVYIFDSEGNRILDGMSGLWCSAVGHGRHAIVDAIADQLRQLDYYNTFFKTTHPGAAELAAAIAQVAPEGFERVFFTSGGSEAVDTVIRMVRHYWAAVGKPGKHIFIARKNAYHGSTIGGASLGGMAPMHAQGGLPIPGIVHVQQPYWWGEGGNMSPEEFGLFAAQEVARAIDEAGPENVAAFIGEPIQGAGGVIIPPSTYWPEVQKICRERDVLLVSDEVICGFGRTGEWFGCQHMGVQPDLITFAKGVTSGYFPLGGVIVGERVAEGLIEQGGEFHHGYTYSGHPGGCAAALATLKIMHEEDLVARVKCEIGPYLQERWLPLANHPLVGEARMVGLIGALELTPHKETRAKFPGEVGTVGLIARDISFREGLVMRAVRDSLILAPPFTLSEEEADDLIATVGRVLDQTLAVVRDRGLMGPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC31</accession>
    <name>A8IC31_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methyl-accepting chemotaxis receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_3153</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Ussery D.W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NfrA_C" evidence="1">
        <location>
            <begin position="979"/>
            <end position="1150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1154" mass="124026" checksum="95098324A0EF700A" modified="2007-12-04" version="1">MTSATEFPKPHVPAAGTMRTMRRLSLAAMLIATVSVTALSIHTPALAQEAPLTGPAWEAADKAYAAYRAKDYTTAADQAREALKFRPDVARLWLLLMDALEAQDKVADAMAAARAASAAGIKDESLTARTRSMSRVLAQAPSLAANKALEARDPKRAQAEIRKAIELVPDDLSYRVLLVYALLADDQLDAAEQAATAAIKVDPQAFLPQILRGYIRERLGRISEAEQDFDRALKDEVLTGTAARDARIVIADAAIAAGRPRRALSVLEPLGNTQDGAITARRDVANAQIANPSVVPRDANRTMPVPYQSCRDTPYGPVCQLVPATTPPGLSGVTSPAYKAAEDAYEAYGKGDDKLAEAKIREALQAFPNNTAWRRLLIDVLERSKQYEALDAAIAQAVAAGDTDSSLLGRRASAQTELGEPLADQAIKELSRRNAKAAADLAQKAVSRAPNTMNYRLLLISALMASGQSKAALAAANDAVKQDETDALARMLRGFLLQQNGNRTEAAADFERALQSNVLTDTEILNYRLIAGNAALAAGQPDQALALLKPIEGEKNADVADQRKLAEQMQANPRRARPALITPSTLCQSTNYGIICSVYYGGTGGGLGGPGMPGYEDATAGFRAMGVKDYAAAAAAARRALASDPGNANYRMLLLSALAGQGKLAEAEATATAILARDPRDGAVLLQRGYLRSRMQNYPGAIADFAAALASGRLKGTEVRNARLAYVDALLGAKQPERALEQLAAFGSDASYDVAARRAFALQALGRHEEALAAFDAAYLRARSPADRLTMLRGGIAELVDLGRSAEAKARFEAAYASGELKGLSTLDMAYLASQAGDRQLAWRYFHEAEEQGGLRRGPGLMDAAYAAKASFQNEDAKRLFMRAIDSANSGEFKTSSQTVYGLRREVSELDRTWGAYVSASYGAVGVAPSSPLAPPPNGGHTIQGGAEIYWRPPGIGYQNGAIFEVFARGFQTWYAENGSSTGWDTTQGSVGVRWKPFATQNLVLESAYLFPIGALAREDWLLRAAYSLGEGTDLRVDVSEWNYWQAYVEGDYYVSQPERIGLFEARWGRAYRADAISRNLMVTPFLAIGGGYDTAYATPFTLGAGPGLNIRYWFREDVYHAPMSYFDLTFQYRFKLAGDDRGEGLFAGAVVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICQ0</accession>
    <name>A8ICQ0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma-70 factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3238</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3238"/>
    <dbReference type="EnsemblBacteria" id="BAF89236">
        <property type="protein sequence ID" value="BAF89236"/>
        <property type="gene ID" value="AZC_3238"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3238"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047691_12_3_5"/>
    <dbReference type="OMA" id="QLEGMSY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="52"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="154"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="216" mass="24438" checksum="9E986C9FF4D06DC9" modified="2007-12-04" version="1">MSYPIHAPLRFMRSPFVASVNRWAMKLAVALQAGMTISDQPSTAVSDLDAIFRLYHRELNRFAYRKLGDREAAADVVQDAFVRYLSADAQRADTARLDSPRFFLWRIVGNLMIDTIRRKRRQGIHATWDEITEDVVDPAPLPDRLLETREEFRLVKEALETLSPNCRQALLLNRVEGLTHAQIAGRLGVSPSMVSKYIMSALRRCMNALAAPDAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID18</accession>
    <name>A8ID18_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC-type branched-chain amino acid transport periplasmic component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2872</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012171396.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2872"/>
    <dbReference type="EnsemblBacteria" id="BAF88870">
        <property type="protein sequence ID" value="BAF88870"/>
        <property type="gene ID" value="AZC_2872"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2872"/>
    <dbReference type="eggNOG" id="COG0683">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_027128_4_3_5"/>
    <dbReference type="OMA" id="HRMGQHQ"/>
    <dbReference type="OrthoDB" id="776281at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Leu-bd"/>
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    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
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    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724341" evidence="1">
        <location>
            <begin position="25"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="2">
        <location>
            <begin position="29"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="390" mass="41678" checksum="7310224D56C75366" modified="2007-12-04" version="1">MVRSAIVSATLALALGVGVPVAQAQEKVVTIGAHMPLTGSLARSGQAFNEGMQVAIRMCNANSPKVQFKVDVIDDESTPAKAVSAVEKLSASGSVAIIGGYGSNIVGPASDAADKLGKVYITAGAVSDELTQRGLKTFFRINNNAGYQRGIANLLIDLKPQAVSIIASTKEAPALLAEGLEKDLAAKGIKVTVHKFDPAITDFKPIINKIKLQDKSDIIMMSAYENDYVGIIRAAKVLKPQVKLIVGAWSLATPKMYTEFPDLMNNVVGTSFLPYPVEVKSPEGQKFAATYKEMFNKDIEYLASLSFVETTLLCEAIQRAATAGTLDKGGLVDEMRKTDRETLLGRLQFDQTGDNPNFALSMGQHRDGKIVLVSPKSAATAEIAYPALPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID33</accession>
    <name>A8ID33_AZOC5</name>
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        <submittedName>
            <fullName evidence="9">Putative acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_2877</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171401.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2877"/>
    <dbReference type="EnsemblBacteria" id="BAF88875">
        <property type="protein sequence ID" value="BAF88875"/>
        <property type="gene ID" value="AZC_2877"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2877"/>
    <dbReference type="eggNOG" id="COG1960">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018204_5_2_5"/>
    <dbReference type="OMA" id="GWSRDVW"/>
    <dbReference type="OrthoDB" id="760677at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="123"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="243"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="384" mass="40638" checksum="2EB6C765A03D310F" modified="2007-12-04" version="1">MNFDLSDEQALLRDTVQRWAATIYPGLEQLEAARRAPLGFLENRWAELAELGLLGLPFAEEDGGFGGGPVELLVVAEALGRALAPEPYLASIVLGGGALRLAGSQAQKDALLPGVIDGSVRLAFAHGEAQARYDLNDVATTARAVEGGYRLDGRKSVVLNADAAQTLVVSARTAGGRRDEAGITLFLVPADAPGVTLAPYPTHDGGRAADVVLADVFVPTEAVLGPQDAALPIIERIIDGGIVALCAEAVGLMEALHELTIEYLKTRKQFGVSIGSFQALQHKAVDMLVALEQARSMALYAAMMVEAEDAEERRVALSAAKAQINRSARFVGQTAVQLHGGIGMTMEYLGAHHFRRLAAIELTFGDTPFHTRRVASEKGLVGAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8ID78</accession>
    <name>A8ID78_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2892</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
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    <feature type="domain" description="AA_kinase" evidence="1">
        <location>
            <begin position="41"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89020.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="277" mass="29009" checksum="72CDE0A6BD50A0DA" modified="2007-12-04" version="1">MSDTTNTIKHVASPLARQTLLDGDLVKPVADKRPIRLLPWLQVVKIGGRSIMDRGAEAILPLVDELRSLLPEHRMLILTGAGIRARHLYSVGLDLGLPVGSLASLAASEAGQNGHMLALLLSAEGVSYVEHPTIASQLAIHLQATRAVVGSAFPPYHHHEFPTSRIPPHRADTGAFLVADAVGAAGLTIVEDVDGVYTADPKGPDGAKAELVRETSASALAAAGGPLPFDHTLTEVMGTARHIERVQVINGLVPGRLTAALRGEHVGTVIHTGAHAG</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3038"/>
    <dbReference type="EnsemblBacteria" id="BAF89036">
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        <property type="gene ID" value="AZC_3038"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3038"/>
    <dbReference type="eggNOG" id="COG1414">
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    <dbReference type="GO" id="GO:0006355">
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    </dbReference>
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        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
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        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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    <dbReference type="Pfam" id="PF09339">
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        <location>
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        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="292" mass="31553" checksum="B90928988FABE49C" modified="2007-12-04" version="1">MCTFPVQFHSVKFYASLNDMSFIWRNMADSTSATGRIFALLRALSRGERQGMRLKDLAAAVDLPRPTTHRLLHGLMAEGMVEHDPRTKHYRLGLELFVLAAKAGSPLNLRDIGRPALLRLTAALGETVFLMVRNGFDAVCVDRSAGPLPIRTFTGDVGGTVMLGVGQAAMAILAFLPDREQDEVIRYNLPRMRALSAFDEGFLRAEIARVRDLGYADGAAGLIPGMAGLGVPILGRDGDAVAALSVGSTTDRMTPERNKVIADLLKREAAEIGARLNPFDPALRRPGAAIMG</sequence>
</entry>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Accepts electrons from ETF and reduces ubiquinone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a ubiquinone + reduced [electron-transfer flavoprotein] = a ubiquinol + H(+) + oxidized [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:24052"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.5.5.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172018.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3495"/>
    <dbReference type="EnsemblBacteria" id="BAF89493">
        <property type="protein sequence ID" value="BAF89493"/>
        <property type="gene ID" value="AZC_3495"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3495"/>
    <dbReference type="eggNOG" id="COG0644">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2440">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009667_4_1_5"/>
    <dbReference type="OMA" id="GGGWMYH"/>
    <dbReference type="OrthoDB" id="1770293at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040156">
        <property type="entry name" value="ETF-QO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10617">
        <property type="entry name" value="PTHR10617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <keyword evidence="9 10 12" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="11">
        <location>
            <begin position="516"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF89493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="556" mass="60644" checksum="1B68A2DE9001FD40" modified="2007-12-04" version="1">MTEAELPEREGMDYDVVVVGAGPAGLATAIRLKQLAEEKGADISVVVVEKGSEAGAHILSGAVIDPIGLDRLLPGWREESDAPLVTQVTDDRFYLLGPAGGIRLPNFAMPPLMNNHGNYIGSLGNVVRWLAQKAEAVGVEIYPGFAASEVLYDDNGAVRGVATGDMGVDREGQPKGEFTRGMELRGRYTVFAEGARGHLTKRLIARFGLDAGREPPKFGIGLKELWKVAPEKHQPGLVQHAFGWPLDGKTGGGAFLYHMEDCQVMVGFVVHLNYQNPYLSPFDEFQRFKTHPTFRDTFEGGKRISYGARAITEGGYQSVPRLSFPGGVLVGCAAGFVNVPRIKGSHNAVLSGMLAAEHLFGPLVEGRGYDEVSSYEAAWRASDVGRDLHRVRNVKPLWSRFGTYLGIPLGALDMWTNTLGFSFFGTQKHGKTDAASLKPASEFKPIAYPKPDGVLTFDKLSSVFISNTNHEEDQPVHLKVRDLDLQKRSEHDVFAGPSNRYCPAGVYEWVEEASGPRFQINAQNCVHCKTCDIKDPNQNIDWTAPEGGGGPNYPNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEM5</accession>
    <name>A8IEM5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Double-transmembrane region</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3511</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172034.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3511"/>
    <dbReference type="EnsemblBacteria" id="BAF89509">
        <property type="protein sequence ID" value="BAF89509"/>
        <property type="gene ID" value="AZC_3511"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3511"/>
    <dbReference type="eggNOG" id="ENOG502Z7KE">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014519_0_0_5"/>
    <dbReference type="OMA" id="TWSNLPL"/>
    <dbReference type="OrthoDB" id="72047at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011933">
        <property type="entry name" value="Double_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025297">
        <property type="entry name" value="DUF4159"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13709">
        <property type="entry name" value="DUF4159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02226">
        <property type="entry name" value="two_anch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="633"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="663"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="BatA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4159" evidence="3">
        <location>
            <begin position="703"/>
            <end position="921"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="941" mass="98620" checksum="9630C90C114BED16" modified="2007-12-04" version="1">MMGLPLSFASPLLLTALLALPALWFLLRVVPPRPKELNFPPTRLLFDIRPKEETPARTPWWLTLLRLLLAALVILAAAGPIWNPPASAPSSSGPLVLVIDQGWPAAATWAQRISTANGLVDEAAANGRGVALIPTGDVPKDATLLLPAQARDKLRSLTPVAWAPARKEAFALAAKILGSQPDAGLVYVSDGVDLATDPDLAQQLAALKGARPPLVVSGGVATPLALAAPDNAAGALTVKVLRPDDGPARVGRVEARDMKGLALGEAAFSFGPGVREALATFNLPVDIRNEVSRLEIVGERSAGAVQLLDKRWRRRTVGVVSGASTDTGQPLLAPTYYLSRALGPFADLRLGETGAPVENINRFLEQRVPVIVLTDVGTIPPATRTRLARFVENGGVLVRFAGPRLANAQDDLLPVRLRRGGRTLGGSLSWETPQALGSLTAEGPFHDLKLPNDVSVNRQVLAEPDGNLGEHTWAALTDGTPLVTGAPRGRGMVVLFHVTADTSWSNLPLSGTFVDMLRRVIALSDAAAATDEGRADTAAARVAQGAVASIPPTRLLDGYGAFGPPGPTAKPVPANFNERASAEHPPGFYGPPDALLAVNALKPDDTLAPLDLSPLGATAAPVREAAPRDLRGLALLAAMALLLLDALAVLVLSGALRRFGRRATTAALLLGALALGAGGILAPSPARADAASDFAVKATSQTRLAYVTTGDAQVDEISRAGLEGLTTFLAQRTALQAGEPMGVDIGKDDLSFFPILYWPVLPNSPVPPPATLARIDAFMKQGGTVVFDTRDALETPQGGSGPLSPAAARLREILSGLDVPELSPIPRDHVLTKTFYLLRDFPGRFTGGTTWVEALPAVQDGDERPARAGDGVSPVIITSNDLAGAWAVGPNGEPLLPLTPGEPRQREMAFRAGANMVMYVLTGNYKADQVHVPALLERLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEU1</accession>
    <name>A8IEU1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Porin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">Consists of 16-stranded beta-barrel sheets, with large surface-exposed loops, that form a transmembrane pore at the center of each barrel. The pore is partially ocluded by a peptide loop that folds into the pore lumen.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the alphaproteobacteria porin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3535"/>
    <dbReference type="EnsemblBacteria" id="BAF89533">
        <property type="protein sequence ID" value="BAF89533"/>
        <property type="gene ID" value="AZC_3535"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3535"/>
    <dbReference type="eggNOG" id="COG3203">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044836_2_0_5"/>
    <dbReference type="OMA" id="ALHYDDS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046930">
        <property type="term" value="C:pore complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015288">
        <property type="term" value="F:porin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003684">
        <property type="entry name" value="Porin_alphabac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02530">
        <property type="entry name" value="Porin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0626">Porin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="472" mass="51178" checksum="6A1BD8F46E794988" modified="2007-12-04" version="1">MDVAFLSVCSAFWTGSNVRVAAFACACKRGAGWCKKRWLREMIQHIIRRNQEAGMKVKGLVAGCGLAVAMIGGANAADLPVKAKGVDYVKVCTAYGQGFYYIPGTDTCLRIGGYLWAEGYYNTYTNYPSVNNKTYSIATAGLIWDARSQTEYGTLRSYFDLRFRWRSSDPWSNGPNGVDVDVWNAYIQFAGFTFGHAQSFFDFYANAGVLGTDPATIGDDTRLNLIAYTHEFMEGLSATVSIEDSADRLAGVVPQDPAAFGTDSLQTGSHVPDFVANLRAEGKWGSAQVSGALHQVRALDLNNQFSATDTWGYALQAGVMVNLPMLADGDNFYLQAAYANGAMSYLGLQNPSGAYIIPDAYLGLAGLSLVSGWNITAQLLHNWNDKWSTTIFGGYAAFDVNNPVAQASYGSTGGNNYNVGGNLAWTPVTNLTIALQYDYTVMEVNNYVATDFSPALASTKAHRGLLFVSRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG09</accession>
    <name>A8IG09_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="9">ALP N-acyltransferase</shortName>
            <ecNumber evidence="9">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">lnt</name>
        <name evidence="11" type="ordered locus">AZC_0012</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168543.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0012"/>
    <dbReference type="EnsemblBacteria" id="BAF86010">
        <property type="protein sequence ID" value="BAF86010"/>
        <property type="gene ID" value="AZC_0012"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0012"/>
    <dbReference type="eggNOG" id="COG0815">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019563_3_1_5"/>
    <dbReference type="OMA" id="IPQSMKW"/>
    <dbReference type="OrthoDB" id="1291198at2"/>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="10">
        <location>
            <begin position="244"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="535" mass="57675" checksum="45434A916BFACE1A" modified="2007-12-04" version="1">MHLANRVRSLTGWRRLGFGLLAGALSALSTAPFGIWPALAVGFPALVLLIDGAGHARRRGRGAMLRSAAAAGWAFGFGYFLASLWWIGAAFLVDAEDFAWLLPVAVLCLPAGLALFTALGAVLARLVWPSGPARLCSFAVAFTAAEWLRGHVLTGFPWNTFGYGPAQTLELAQGAAFVGLWGLTFFSLLLLSTPVLLLRSGTFTRRAGWPLAALAVIALAYGLGGYRLSLNPSRYLEQVRLRIMQPAIPQGEKFAYDRRQAVLENYLDLSGRPSALYPKGLEDIGLLVWPESAFPFIYEREPWAKARIAATLPDNVTLVTGAARVGMPPEGQTSPFFNSIRVMNARGEVQETADKVHLVPFGEYLPFQDFLESIGLEQLTRVRGGFASGDRLRPLKLPGAPDAAPLICYEAIFPGAVLPQGERPGFLLNVTNDAWFGDTPGPYQHFLQARLRAVEEGLPLIRAANTGISAIVDPLGRIVAEQDLGVRGVVDGDLPQRLNAPPFGSRHAGGVLLVLMGITSSVAISRVRRQHARIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG23</accession>
    <name>A8IG23_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truB</name>
        <name evidence="8" type="ordered locus">AZC_0022</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0022"/>
    <dbReference type="EnsemblBacteria" id="BAF86020">
        <property type="protein sequence ID" value="BAF86020"/>
        <property type="gene ID" value="AZC_0022"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0022"/>
    <dbReference type="eggNOG" id="COG0130">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032087_0_3_5"/>
    <dbReference type="OMA" id="IYELEMT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="6">
        <location>
            <begin position="64"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="7">
        <location>
            <begin position="213"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="340"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="29"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="362" mass="38965" checksum="409984C78721CF4D" modified="2007-12-04" version="1">MNAPFPRPEEAEAAEQRAPGAPRGRGPRQQRDQAPRAPKRDIDGWVLLDKPSGMTSTQAVAVVKRLFAAKKAGHAGTLDPLASGCLPIALGEATKTVPYIMDGRKTYRFAVTFGVETDTDDSEGKSVATSDHRPSDADIEAALDSFLGEIMQVPPAYSALKIAGERAYDIARGGNEVVLEARPVTIHRIEIVERPDADTVVLEAECGKGTYVRAIARDLGRMLGTRGHVSMLRRACVGPFLEEDLVPMDELQARAEASEADLFDALDPVDSALEEIPHLSVTPSDAHRLRCGQSVILRGRDAPILDGHVAIFCQEALIAIGDAQGGEVLPHRVFNWAKSHRPRPAGGAPAARLHRDPPVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG72</accession>
    <name>A8IG72_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">wbpY</name>
        <name evidence="2" type="ordered locus">AZC_0050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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    <evidence type="ECO:0000259" key="1">
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            <dbReference type="Pfam" id="PF00534"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86048.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="375" mass="42579" checksum="819BD5386E3FF4B3" modified="2007-12-04" version="1">MKTVFLDITELRGNPVRTGIQRMVRQLLKAWPTDVEAVPVVYDSVREALRIISQETVEFLIESGDTPSMPLRDAVDQVNFLDDPARSPTVTLREGDKVHIPELFFDEKRTVFHRKAIASGVDLSVWIPDFIPWLRPECFPRIPSFHPYMHYLWLVFEARKRAFISAAVRDDFECRIYRRPSQGTIVTDLGADAINIGQQTFNADRKDLIFLGTLEPRKAQHVVYNAFIGRTRHPDLRLTFIGAIPEHGIPADFMPLVKSKRPDVRLLTEANDSDVAEIFKGARATVYTSQVEGYGLPPMESLYAGVPVIVRDNLPALVGKPDFGQLRLGRGDEEDIRSAIDIIGDDQRCAALWEDARRFPSRTWQAVARQIADWA</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <comment type="similarity">
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        </source>
    </evidence>
    <sequence length="402" mass="43838" checksum="672F8367BB1B6021" modified="2007-12-04" version="1">MPDTMPTSATTPSDDRRSPFVRLADLLAGIEPGRPPLIAAVGEPQHAFADFVASALHDTLEGFGRYPRQEGTPEFRAAVAEWLGKRYTLARPVDPDREVLALNGSREGLVSATFIARRRGPERKGAPIVLVPNPLYAAYRAGAELAGCEVVPMPTTRESGWLPDLDALDPALLDRAVVLFLASPANPQGAVASREYLTRLMEMTRRHGVYLFADECYSEIYLEEEKPTGVLEVAEGNFSGILSFNSLSKRSSLPGLRVGFVAGDPVFLRDFLAFRGIACPQVPEPLQAVAVAALQDEAHVIASRMLYKSKFDIADRLLHKRFGYKRPDGGFFLWLDVSDAGGGEAAALRLWKEQGLRTVPGGYLASRDLTGHNPGEPYLRVAMVHDLTTSEEVLNRLIAGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGP6</accession>
    <name>A8IGP6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane autotransporter barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0117</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168648.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0117"/>
    <dbReference type="EnsemblBacteria" id="BAF86115">
        <property type="protein sequence ID" value="BAF86115"/>
        <property type="gene ID" value="AZC_0117"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0117"/>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG5295">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005887_4_0_5"/>
    <dbReference type="OMA" id="RVEYQHD"/>
    <dbReference type="OrthoDB" id="1713183at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006315">
        <property type="entry name" value="OM_autotransptr_brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03797">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01414">
        <property type="entry name" value="autotrans_barl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723626" evidence="1">
        <location>
            <begin position="27"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="2">
        <location>
            <begin position="861"/>
            <end position="1138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1138" mass="112126" checksum="DE988DC229047FC2" modified="2007-12-04" version="1">MRCLSSSVSRTAIACALAFAPAPVLAASFTVPTGSTNTTVQTLTGTQTGAVSVGGTLSTTASSVTLGIATGTGVVLNNAGTISSGNRAVDTTSTVTGLLTVNNGGAITATDDGFRINGTLAGGTLLLSNSGTIVSSTGQALDFDKATATNAIVTITNSGSIQSSGSDAVRLGGGTISLSNSGTISTTSAGKRAIKFDTASNVDTLVSLSLTNGIGGLISGTDDAIKIAGNAGSTSAAVIAINNAGTIRSTAGGQGIDLGDLTSTSLKITITNQSTGLITASDNDGVKAGMNTVVSNYGTITSNYTTTSADAQNYSAVKFDGASGAVHNYAGGVISGAYHGIKASGLTDNIDVINDAGGTITGRNGSGVNSNGTGSVLNYGIITGSFDPAASFGDGDGVDIDHIGTIVNYGTIQALGSKGTKPGETKPSTSEGIAIGGGSITNGSATVRTALISGANNGILADDSNSGSIYGALTVTNYGTIQGLNGYGIQVVNNAGFATTITNYGTISGTTYAVAMGNGNDLFVYEAGSSVNGAVKGEGGTDTLRLGEVAGTFNLSLLGDSATYQGFEILDLAIGSGWTVTGSSSFSGATNVTGASLTLNNASLAASVVTVGGSNAVLAGTGTIGSLVANSGATISPGLTASGLGTLSVNGAARFNSGSTYAVTVTNSGASDRIAVSGATTLSTGASVSVQAIAGLYNFRQTYTILTSAGGISGTFGPVSSNFAFLTPSLSYDANTVYLALNRNDTTFASVATTRNGRQAAAAVEAGGPNTALYNAVATGSITASQSAFQLLSGEAQASFGTTAFNQNQMVGDVIDARLRQSNYAGATGAAAGLGAGGPTAYANERAVKAGPFSSAAAPAPAPQAWTGWVQGYGQWNHLSGNGNASTLDSTVGGVLAGLDTSVNNWTLGFAAGYGWSNSSVANLGSQVNSDTAQFAFYAGTAFGALKLRAGATLAYSNVDSNRVVVVGSLTERPTASYDGWSGGFFGEAGYALPVGPVAFEPFAQLAWSGVNMGSFAETGAPVTGLSSSGLSFDTWYTTLGLRAAGAVSFAGYNIVPHASVGWRHAYGDVTPALAVTYLNTGTGFTVQGLPIAEDSAVLGAGLDLALGKGFTVGVSYDGAFASSSQSNAVRGTVGFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGT2</accession>
    <name>A8IGT2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0131</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0131"/>
    <dbReference type="EnsemblBacteria" id="BAF86129">
        <property type="protein sequence ID" value="BAF86129"/>
        <property type="gene ID" value="AZC_0131"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0131"/>
    <dbReference type="eggNOG" id="ENOG5033DTY">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2476679_0_0_5"/>
    <dbReference type="OMA" id="MAREGHF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3277"/>
    <dbReference type="EnsemblBacteria" id="BAF89275">
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        <property type="gene ID" value="AZC_3277"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3277"/>
    <dbReference type="eggNOG" id="COG2814">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_001265_61_1_5"/>
    <dbReference type="OMA" id="MGQFTLF"/>
    <dbReference type="OrthoDB" id="1384345at2"/>
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    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0022857">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS_dom"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF07690">
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        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="79"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="233"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="21"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="398" mass="40777" checksum="86B2B7E49E51B19D" modified="2007-12-04" version="1">MLTSSKPDLAVVQRGTAAWGAVLALALCAFALIASEFMPVSLLTPISADLGISEGQAGQAISVSGAFAVLTSLFIASLAGSLDRKVLLLALTGLMIASGAIVAAAPNYAVLMAGRALIGVVIGGFWSMSAATAMRLVPEAQVPRALAILNGGNALATVVAAPMGSFLGGLIGWRGAFFCVVPVAVLVFLWLLASLPTLPVERRPAAPGAFRLVWWPVVGWGMAAVSLFFMGQFTLFTYLRPFLEAVTRVNVPTLSLILLVMGVTGFVGTSLIGAALRRSLYGTLVVIPALMGGIGLALTLFGGSPLATALLLAGWGFLSTAAPVGWWIWLSRTLPQDAEAGGGLMVAVVQLAITLGATVGGLLFDLRGYDATFGTAVVLLVLAALLAWRTAGVARASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="41" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3366"/>
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        <property type="gene ID" value="AZC_3366"/>
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    <dbReference type="KEGG" id="azc:AZC_3366"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="581" mass="65311" checksum="15A189004EAE0F44" modified="2007-12-04" version="1">MMVVDDAARVAPDFSQARDILSTMEVRLPGRRLADGGVAQDLVLPVRLFMYGPFLRLPEGRYCLSFDGDFSAPVQKGHPMLGVEVIAQNRMLRAWRDFTHEELRAGDRSLFFEVPHALSMESGADAPFEFRFTGFGTSRFTISGLTLRTASEAETAAAPPMRWRMLGRLRLVPASGPVGLSPVSVSALKFWRSWSPLFLPAGLHRLEVAARVGAVSQPDEPALEISVRTRDGGVLGTEVFSSAQLAGERGSFLFEVPPDASLDSGVPQKIDIGIRHFRKASLKLDALDIVHLPAGTGPAAGVFAKTVRGATTRKKILVFGNCQGSLVARAFRENPGFSKQFSVKHHFMELPPNLHEQGRRDIEECDLLLIQDIKEWEQYPLKEHVPADLPTLRYPCVRFASLWPFDAFNGPDDKFARNKDYPNFEFTYFDGLLARLRKEIPDPEARFAAYRDLDVKGVIDPKRLHTFEEKRLLAMDEKFPAGMGAYILENFRRKRVFYTTAHPNGAILSMLMKYLAKELGVRQLFWFSGPLDSLRSLQIPVHPKVAAALDVRWAGADARYLVRGEKVTWEDYFRKYISYYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJX7</accession>
    <name>A8IJX7_AZOC5</name>
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            <fullName evidence="8">Conserved hypothetical transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0373</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the auxin efflux carrier (TC 2.A.69) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168904.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0373"/>
    <dbReference type="EnsemblBacteria" id="BAF86371">
        <property type="protein sequence ID" value="BAF86371"/>
        <property type="gene ID" value="AZC_0373"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0373"/>
    <dbReference type="eggNOG" id="COG0679">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056175_2_1_5"/>
    <dbReference type="OMA" id="SPFRLWI"/>
    <dbReference type="OrthoDB" id="2033473at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004776">
        <property type="entry name" value="Mem_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03547">
        <property type="entry name" value="Mem_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="312" mass="32584" checksum="BC8520B562B867DD" modified="2007-12-04" version="1">MLGILADLALIVLPVFGIVGVGYGAAKTRLISDSASDGLAEYVFSLAVPILIFKTLSESKLPDAQPWGYWIAYFTGAFAVFALAAVVAAKVFKRSHTEAVIHGFSAGQANTVFVGVPLILKAYGEAGAVPLFLLIAVHLPVMLVAATIAVEGGSGFSRATVKRLFRSLAFNPILLGIYAGGIGRLMGFEAHGVLKQVLDMMAASATPCALVSLGLALKRYGISGDLRPTVFISTLKLIVHPLLVLGLTRILPMPPVWAGVAVLFAAMPCGINAYLLAQRYGVGVGTSSSSVSLSTALGLFTITFWLYVLGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0374</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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    <sequence length="276" mass="29592" checksum="6A2321FA07D90CCC" modified="2007-12-04" version="1">MELPAAARLPITWRGVRPVDGPPRLASQRIRALPATPCPMHPPCRVPNAQMPMSLIAPLSPETPDGLLLIGGGRNARNLICIFETAGVAVRGIADDRPAGKVLGHTVGFIDDLNGSDVAAFLTIADPDHAAQVRERPALRGCRWPRFVHPSSVVSSHADISEGCYVGPFAILTDVVLGRHVHLFAHNVLGARVRVGDFTVILPHATLASDVRIGKRCMIGMGARIHAGVTIGDDCRIGVNAVVRRDMPDRAIAVSQQATRIKTRLSFATRRSVPVE</sequence>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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    <keyword evidence="1 3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3'-5' exonuclease" evidence="2">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="206" mass="22441" checksum="9434C9D310311ABD" modified="2007-12-04" version="1">MTIRLHRGDLPDSFQPAPVVAIDTETLGLKPHRDRLCVVQLSNGDGTADVVQIPAGATAESAPNLVRMLADPNVVKLFHFGRFDIAVLLHTFGVTTAPVFCTKIASRLTRTYTDRHGLKDLVRELLGVDLSKQQQSSDWAASELTDAQLAYAASDVLHLHACKEKLEAMLARDGRTALAAECFKFLPARAALDLAGWPDEDIFAHS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKU6</accession>
    <name>RS16_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpsP</name>
        <name type="ordered locus">AZC_3952</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172472.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IKU6"/>
    <dbReference type="SMR" id="A8IKU6"/>
    <dbReference type="STRING" id="438753.AZC_3952"/>
    <dbReference type="EnsemblBacteria" id="BAF89950">
        <property type="protein sequence ID" value="BAF89950"/>
        <property type="gene ID" value="AZC_3952"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3952"/>
    <dbReference type="eggNOG" id="COG0228">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100590_3_1_5"/>
    <dbReference type="OMA" id="HMSEPAA"/>
    <dbReference type="OrthoDB" id="1937072at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020592">
        <property type="entry name" value="Ribosomal_S16_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00732">
        <property type="entry name" value="RIBOSOMAL_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <feature type="chain" id="PRO_1000072192" description="30S ribosomal protein S16">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="85"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="121" mass="13244" checksum="F71934D378B3F2BE" modified="2007-12-04" version="1">MSLKIRLARGGAKKRPYYRIVVADARSPRDGRFIEKIGTFNPLLAKDAAERVTLDTEKAKAWLEKGAQPTDRVARFLDAAGLLKREARNNPKKAEPGKKAQERAAERAAKAAEASEAASAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8IL45</accession>
    <name>A8IL45_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyltransf_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3987</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3987"/>
    <dbReference type="EnsemblBacteria" id="BAF89985">
        <property type="protein sequence ID" value="BAF89985"/>
        <property type="gene ID" value="AZC_3987"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3987"/>
    <dbReference type="eggNOG" id="COG3146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062615_0_0_5"/>
    <dbReference type="OMA" id="WMVNLEY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="211"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="404" mass="45988" checksum="578DAF559C095A09" modified="2007-12-04" version="1">MSCCRPCASRFKAARGRQAVRVSAVSEFGRLPEAMWDICFPGEVENLRYYQACAAARPAQTHVRALIANGTQRPEAVAPLFRMEYALHTSIQDGWLGAAMRRLDRRFPRLFRLPMLGLGSPFAERCHCGFPPDMDEADRLRAADRLLDLLERQAHLENIGLTVIKDIHEDDLPAFRPHLLARGYTRMSSLPVAVLHLPYATFDDYLASLSRSTRKDMKRKLRDAANVEIEYRHDISDIGDEIFALYEQTRLESPSDYGDFEQLPADYFTRVVAALAPRAFCVCYRIDGVLAAFNLLMVEEDRVIDKFLGMNYPLARTHDLYFISWMENVRYCIANGKTRLQTGQGTFANKLRLGSVLEPMHNYFRHRSPMLNAMLRAISPLLGFEELDPSLQAARRPAPGRVQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM02</accession>
    <name>A8IM02_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
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    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; fumarate from succinate (bacterial route): step 1/1.</text>
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    <comment type="subunit">
        <text evidence="4">Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
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        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
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            <end position="192"/>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="9">
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
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        </source>
    </evidence>
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            <dbReference type="EMBL" id="BAF89744.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="261" mass="29690" checksum="9A237780BADEE18C" modified="2007-12-04" version="1">MAEFTLPKNSQITKGKTWPKPQAAKKVTEFRVYRWNPDDGKNPSIDTYYVDREACGPMVLDGLIYIKNHIDPTLTFRRSCREGVCGSCAMNIGGTNTLACTKGMDEVLVKGSVNIYPLPHMEVVKDLVPDLTRFYAQHASIEPWLQTDSAAPEKEWRQSKEDRERLDGLYECILCACCSTSCPSYWWNGDRYLGPAALLQANRWLKDSRDERTGARLDNLEDPFRLYRCHTIMNCAQACPKGLNPAKAIAEIKKMMVERQI</sequence>
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            <fullName evidence="6">ABC transporter ATPase subunit</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="gene ID" value="AZC_0751"/>
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    <dbReference type="KEGG" id="azc:AZC_0751"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_6_1_5"/>
    <dbReference type="OMA" id="LWPEYHP"/>
    <dbReference type="OrthoDB" id="1857145at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="128" mass="13321" checksum="96DEE8325C07A942" modified="2007-12-04" version="1">MIDHLGLAVSDLERSRSFYLAALGPIGATVQMQVSAQESGGHAHIGFGVAGKPSFWISDATPVSGPLHVAFAAPDRASVDAFYAAALAAGGRDNGAPGLRLHYHPNYYAAFVLDPDGNNVEAVCHHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQP7</accession>
    <name>A8IQP7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0806</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0806"/>
    <dbReference type="EnsemblBacteria" id="BAF86804">
        <property type="protein sequence ID" value="BAF86804"/>
        <property type="gene ID" value="AZC_0806"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0806"/>
    <dbReference type="eggNOG" id="COG0624">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021802_7_0_5"/>
    <dbReference type="OMA" id="AEADMRY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017150">
        <property type="entry name" value="Pept_M20_glutamate_carboxypep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037238">
        <property type="entry name" value="Carboxypeptidase_G2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="166"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037238-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="365" mass="38262" checksum="B5EFDFA0C70D56D3" modified="2007-12-04" version="1">MEALLKRLVNMESSSFDKEGTDKVGEVIAEILTAEGILVTRLPQQGYGDVFRAEVHGRAGGAHALLLGHRDTVFAKGTVANRPYSRKDKLAFGPGVCDMKAGLVTNIFTLRAIKAVGGLSFPVVALFTGDEEIGSGTGRPEIERAAYGARAVFNTEPGRVSGNVVTGRKGGGSFLIKVTGKAAHSGVNHKDGASAIETLARKIVKLHALTDYEAGITTNVGVIKGGNTHNTVAPWAEAELDLRFVTLDQHKAMTAEIERIVAEPEVPGTTATVTPKSMFLPLEEKHAAGLFALYREAATKDVGFDVGGEFTGGCADSGFTASLGVSTLCGLGPIGGKAHTDDEFCELDSLVPRTQALAATLCRLA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-10-01" modified="2022-05-25" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>Q07739</accession>
    <accession>A8IP13</accession>
    <name>NODA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Nodulation protein A</fullName>
            <ecNumber>2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">nodA</name>
        <name type="ordered locus">AZC_3818</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1989" name="Mol. Gen. Genet." volume="219" first="289" last="298">
            <title>Common nodABC genes in Nod locus 1 of Azorhizobium caulinodans: nucleotide sequence and plant-inducible expression.</title>
            <authorList>
                <person name="Goethals K."/>
                <person name="Gao M."/>
                <person name="Tomekpe K."/>
                <person name="van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
            <dbReference type="PubMed" id="2615763"/>
            <dbReference type="DOI" id="10.1007/BF00261190"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text>N-acyltransferase required for nodulation. Acts in the production of a small, heat-stable compound (Nod) that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NodA family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-"/>
    <dbReference type="EMBL" id="L18897">
        <property type="protein sequence ID" value="AAB51162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="JQ0393">
        <property type="entry name" value="JQ0393"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q07739"/>
    <dbReference type="SMR" id="Q07739"/>
    <dbReference type="STRING" id="438753.AZC_3818"/>
    <dbReference type="EnsemblBacteria" id="BAF89816">
        <property type="protein sequence ID" value="BAF89816"/>
        <property type="gene ID" value="AZC_3818"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3818"/>
    <dbReference type="eggNOG" id="COG3153">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_098284_0_0_5"/>
    <dbReference type="OMA" id="FPIGRPM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00084">
        <property type="entry name" value="NodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003484">
        <property type="entry name" value="NodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020567">
        <property type="entry name" value="Nodulation_prot_NodA_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02474">
        <property type="entry name" value="NodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04245">
        <property type="entry name" value="nodulat_NodA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01349">
        <property type="entry name" value="NODA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0012">Acyltransferase</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0536">Nodulation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000196329" description="Nodulation protein A">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="226" mass="24916" checksum="F1992B421A002315" modified="1994-10-01" version="1">MMVHNYCAPENVTAPPHVSRVTQYNKRGIRMISKVTWRVAWESDLTNGDHAELSDFFKSVYGATGAFNALPFAGGRSWAGARPELRGIAYDESGVAAHMGVLRRFIKVGGEQIAVAELGLYGVRRDLEGLGIGHSTLAMLPVLKALGVPFAFGCFRNELRIHFQRFCRNGKGAIVDNVNIKSTQPDIYPDLPPTKIEKKAAVILPLTETLDRWPEGVDIERNGPEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRP8</accession>
    <name>A8HRP8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4075</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="696" mass="76123" checksum="59A49A50C13AC6C7" modified="2007-12-04" version="1">MNQHVSAPVIRASACPHDCPSTCALEVEVLDRKRIGRVRGAKDNSYTAGVICAKVARYAERTDHPERLMHPLRRVGPKGSTQFERISWDEALDRVAEGLLKAEQAHGAESVWPYYYAGTMGLVMRDGINRLTHAKKYSRFFSSICVNPAWSGYIAGTGRLGGTDPREMGVSDLVIIWGTNAVATQVNVMTHAVKARKERGAKIAVVDVYRTPTMEQADIPLLIRPGTDGALACAIMHVLFRDNRADRAYLARYANDAAEFEAHLATRTPEWASAITGLPVAEIEAFAKLVGETPRSFFRIGYGLSRSRNGAVNMHAVTSIPVVSGAWQHEGGGAFHSNSGIYRTRKTMIEGLDVLDAKVRQLDQSRIGAILTGDPEVLSGGPPVTAMLIQNTNPMSVAPDQERVKQGFARDDLFVAVHEQFLTETARQADIVLPATMFTEHDDLYQGGGHQHLLLGPKLVDPPGECRSNHEVIAEIARRVGAEHPGFSMSPRELIDWTLNASQRGTLEHLEAERFIDIQPEFESAHFLSGFGHKDGRYRLKPDWTRPPIPAPGLFGPWEQMPEFPDHWAVIEAPTAEHPFRLVTAPARNFLNSTFNETPTSVKREGGPTLLIHPEDAAARSIAEGDTVEVRNTRGTVALTAKLFDGLRRGVVVAEQIHPNFAHAGGRGINTLTGADPVAPAGGAAFHDNRVDVVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSB3</accession>
    <name>A8HSB3_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_4162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172682.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4162"/>
    <dbReference type="EnsemblBacteria" id="BAF90160">
        <property type="protein sequence ID" value="BAF90160"/>
        <property type="gene ID" value="AZC_4162"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4162"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_5"/>
    <dbReference type="OMA" id="DQALDIC"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
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        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="298" mass="32805" checksum="3C99D593130D6D95" modified="2007-12-04" version="1">MLSTRQLRYFEALSRHLHFGRAAEECAVTQPALSMQIRDMEADLGVDLVERGRGSVRLTPMGEETAVRAREILASLTDLERSIRAQGSLLEGRLRLGVIPSVAPYLLPRLLPAVGQAYPRVELALRETQTEQLVAELLNGSLDLLILSLPVEHPALETRALFDDAFLLALPEGAELPEGDLATPDHLAPDDLLLLEDGHCFRDQALQVCGAMDQRRLRRFGATSLSTLVQLVANGQGVTLLPEMLVACEGGQIPRVRLVRFPEPAPRRSIGMVWRRSSPFVRDIAAFARLVEGCRPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT96</accession>
    <name>A8HT96_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
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    <gene>
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        <name evidence="3" type="ordered locus">AZC_0813</name>
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    <organism evidence="3 4">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012169344.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0813"/>
    <dbReference type="EnsemblBacteria" id="BAF86811">
        <property type="protein sequence ID" value="BAF86811"/>
        <property type="gene ID" value="AZC_0813"/>
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    <dbReference type="KEGG" id="azc:AZC_0813"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_039613_6_0_5"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
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        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
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    </dbReference>
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        <property type="entry name" value="HTHLYSR"/>
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        <property type="entry name" value="SSF46785"/>
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        <property type="entry name" value="HTH_LYSR"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="309" mass="33856" checksum="9C1F6825E6A87662" modified="2007-12-04" version="1">MGDAALRYFLEVVRSGSIAEASVRLNVAASAISRQIAKLEAELGSPLFERRSRGMVPSAAGELLAQHARRTLLGEEQVVSEIRRLRGLERGLVRVGCTEGFATDFMPEAIGMFRHTYPGIAFDMRVAAPQAVTRMVREGEIDIGLTFGFMPDASVQVEFGGSAPLMALVGLDHPLANRPWVTIADIAAFPLGLPAKDTTARQLFDLVCGAEGIAVEPMLTTNYMSGLWRFAETGGGVTVTGRITVLSRIWRFHVVALPLRSKTSNERRYEIQSMLGRTLPDAARAFVFHLRRHLEQLDRPGDQPLGLRS</sequence>
</entry>
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    <accession>A8HTI1</accession>
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        <submittedName>
            <fullName evidence="3">Putative DNA packaging protein GP2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0839</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0839"/>
    <dbReference type="EnsemblBacteria" id="BAF86837">
        <property type="protein sequence ID" value="BAF86837"/>
        <property type="gene ID" value="AZC_0839"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0839"/>
    <dbReference type="eggNOG" id="COG5565">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1105365_0_0_5"/>
    <dbReference type="OMA" id="WDHPFGA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035421">
        <property type="entry name" value="Terminase_6C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17289">
        <property type="entry name" value="Terminase_6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Terminase_6C" evidence="2">
        <location>
            <begin position="72"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="227"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="251" mass="28802" checksum="12299BBB04C08BB6" modified="2007-12-04" version="1">MSRFCIQATWDDVPHLTQQQKDELWAAIPAHMRDARTKGIPVLGSGRVFPIAEELILCDAMPIPKHWARINGLDFGWDHPFGAVSIAWDRDADVIYVVNTYRAREESSVIHAAAIRPWGKKIPCAWPHDGFQHDKGSGQQLAEQYRDHGLEMLDEHATHEQGGNGVEAGIMEMLERMQTGRLKVFRHLEDWMSEFRLYHRKDGKIVKERDDLMSATRYAIMMKRFASPEPTGPIDRHRAVRDRPRGSAWTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU50</accession>
    <name>A8HU50_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Farnesyltranstransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0907</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169438.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0907"/>
    <dbReference type="EnsemblBacteria" id="BAF86905">
        <property type="protein sequence ID" value="BAF86905"/>
        <property type="gene ID" value="AZC_0907"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0907"/>
    <dbReference type="eggNOG" id="COG0142">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014015_2_0_5"/>
    <dbReference type="OMA" id="GKQMRPM"/>
    <dbReference type="OrthoDB" id="1861068at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="335" mass="36070" checksum="0635030CB223AC8F" modified="2007-12-04" version="1">MAVVLPFEPKEPSIETLVRLVKGDMERVNALILSRTGSDVAMIPEVANHLISSGGKRLRPMLTIACAALSSYEGDGHIKLAASVEFMHTATLLHDDVVDESDMRRGKLAARKLWGNEASVLVGDFLLGQAFKMMVEVGILECLDILSTAACTIAEGEVMQLAAAKNTETSEDDYLAVIRGKTAELFAAACEVGAVLNARPKAEQAACRSFGMNLGIAFQLVDDALDYGGSQAKLGKNVGDDFREGKITLPVLLAFRRGDAEERAFWKRCLETGETTDENLAHAVGLLTKHRALADTIERARHYGAMAKDALALFPASHAKDALAEAVDFCISRAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU97</accession>
    <name>A8HU97_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sulfate transport system permease protein CysT</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cysT</name>
        <name evidence="12" type="ordered locus">AZC_0921</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell inner membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169452.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0921"/>
    <dbReference type="EnsemblBacteria" id="BAF86919">
        <property type="protein sequence ID" value="BAF86919"/>
        <property type="gene ID" value="AZC_0921"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0921"/>
    <dbReference type="eggNOG" id="COG0555">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016047_14_0_5"/>
    <dbReference type="OMA" id="AQLTWDQ"/>
    <dbReference type="OrthoDB" id="1584669at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015419">
        <property type="term" value="F:ABC-type sulfate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011865">
        <property type="entry name" value="CysT_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005667">
        <property type="entry name" value="Sulph_transpt2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406">
        <property type="entry name" value="PTHR30406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30406:SF8">
        <property type="entry name" value="PTHR30406:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00969">
        <property type="entry name" value="3a0106s02"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02139">
        <property type="entry name" value="permease_CysT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0764">Sulfate transport</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="11">
        <location>
            <begin position="66"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF86919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="283" mass="30702" checksum="574D88200FD65471" modified="2007-12-04" version="1">MAAATRASFFRPRSVIPGFGLTFGLTVTWLSLIVLIPLAALFLKTTELTLDRFIAVVTGPRTLHALWVSFGISFAAAVVNAVFGTIVVWALVRYDFPGRRLVDAIVDVPFALPTAVAGISLTALYAENGWIGSLLAPLGIKVAFTPLGILVALVFVGLPFVVRTIQPVLADLDKQYEEAAASLGASRFETIWRVVLPTVWPALLTGFSLAFARGIGEYGSVIFIAGNMPNVSEIAPLLIVVRLEEFRYADATAIAVVMLVASFILLLIINRLQQWTERRTSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A8HUG1</accession>
    <name>A8HUG1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ordered locus">AZC_0941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
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            <name>Zn(2+)</name>
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        </cofactor>
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    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
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    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
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        <location>
            <begin position="47"/>
            <end position="122"/>
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        <location>
            <position position="94"/>
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        <ligand>
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        <ligand>
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            <position position="120"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    <evidence type="ECO:0000256" key="3">
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    </evidence>
    <evidence type="ECO:0000256" key="4">
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    <evidence type="ECO:0000256" key="6">
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    </evidence>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03397">
        <property type="entry name" value="PAP2_acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001011">
        <property type="entry name" value="Acid_Pase_classA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="acidPPc" evidence="1">
        <location>
            <begin position="122"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="282" mass="29962" checksum="A8A7B12603D97943" modified="2007-12-04" version="1">MRPQTAPSSRTDISRLAVRRSRLSPLFALGALALVMAGPVLAAGPDYIRPDQVDLIRILPPAPAPGSATTQEDFRILLDYQKARTPAQVAAANEDVKRHPARFSEAVGTDLSKSAAPITDEVLDHAWKQAYALVSVTKQYWNRQRPYLANPEIHLVLPAEDTASYPSGHATYGMFMAILLANMVPERAGIIMDRGREYGIERLIGGVHYPSDVEAGRITGSVLAAEVLGNAAFKADLARAAAEVRTALKLPPLSPAIMPAQAPLPAGGATALPLPAAAAPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV03</accession>
    <name>A8HV03_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoadipyl-CoA thiolase</fullName>
            <ecNumber evidence="4">2.3.1.174</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_0996</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + succinyl-CoA = 3-oxoadipyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:19481"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57348"/>
            <dbReference type="EC" id="2.3.1.174"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Aromatic compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.174" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169527.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0996"/>
    <dbReference type="EnsemblBacteria" id="BAF86994">
        <property type="protein sequence ID" value="BAF86994"/>
        <property type="gene ID" value="AZC_0996"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0996"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_2_2_5"/>
    <dbReference type="OMA" id="WGCANQA"/>
    <dbReference type="OrthoDB" id="550338at2"/>
    <dbReference type="UniPathway" id="UPA00653"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033812">
        <property type="term" value="F:3-oxoadipyl-CoA thiolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019619">
        <property type="term" value="P:3,4-dihydroxybenzoate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012793">
        <property type="entry name" value="PcaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02430">
        <property type="entry name" value="pcaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="8">
        <location>
            <begin position="5"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="9">
        <location>
            <begin position="277"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="401" mass="41436" checksum="F15F384179E7FA21" modified="2007-12-04" version="1">MTEAYICDYIRTPIGRFGGALSAVRADDLGAIPLKALVARNAGLDWEKVDDVIFGCANQAGEDNRNVARMSLLLAGLPLSIGGTTMNRLCGSGMDAVATAARAIKAGEADLIIAGGVESMSRAPLVMPKADAAFSRRAEIYDTTIGWRFVNPLMKEMYGVDSMPETGDNVAIDYKVSREDQDAFAVRSQEKASAAQANGRLAREITPVTLPQKKGDPVVVERDEHPRATSLEALAKLKPVNRMAGATVTAGNASGVNDGAAALIIASEAAAKAHGLTPIARVLGGAVAGVPPRVMGIGPAPASQKLMARLGLTQDQFDVIELNEAFASQGLATLRLLGIADDDARVNCNGGAIALGHPLGMSGARITGTAALELTVGGGRRALATMCIGVGQGIAVALERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8HW29</accession>
    <name>A8HW29_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative hemin transport system permease transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_4386</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF90384">
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    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
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    </dbReference>
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        <location>
            <begin position="338"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF90384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="363" mass="36542" checksum="0E9C7DE8306588B7" modified="2007-12-04" version="1">MSLAALKATAHAHPRRLRPAAPAGLVACALLAALAFLAALAVGAVSISPGRVLEILAGAFSTPADEAGAAMRERIVVLDIRLPRAVLGLLTGAGTAMAGAVMQGVFRNPLADPGLVGVAPGAALAAVSFFVLGAPLVALLPPLAQTLALPLCAFAGSLITTLLIARLSMREGAMSVATLLFSGLALGALASAGTGLLVFISSEQQSREFVFWTLGSLGGATWPKVALVAPFVGFLVVCAPVLARGLDALALGEAEAFHVGVPVERLKRLAIIAVAAGVGACVAAAGVIGFIGLVVPHLVRMWLGPGHRVLLPASALLGAAVLIAADICARIAVAPAELPLGVVTALVGAPFFLWLLLRRRMIG</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4415"/>
    <dbReference type="EnsemblBacteria" id="BAF90413">
        <property type="protein sequence ID" value="BAF90413"/>
        <property type="gene ID" value="AZC_4415"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4415"/>
    <dbReference type="eggNOG" id="COG0628">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="AVFFWSF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="19"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="349" mass="37510" checksum="7A227ACFF26D43B2" modified="2007-12-04" version="1">MATGAGTGMDAFKGQKILIGLIATVVLAAAVSLAQVILAPVVFAIFVIAVVWPVQRRLEQRIGTGLASLLTLLLTLAVIGSIVSMVVWGFSHVAQWTFANAGRFQAIYAQAGDWLEGHGFLLAGSVADHFNVRWLLRALQEISARANSLASFLVVTAVFVVFGLLEADIFVRQVARLPRYGAFLMASGADIASKMQTYMWVRTLMSIATGILVWGFTLASGMELATAWGVIALALNYIPVIGPFTATLLPTVFALVQFESWRMALFVFVVLNVVQFVSGSYLEPRIAGRTLAISPFLVLFAVFFWSFLWGLAGAFIGVPLVIAALTFCAHGTGTRWIADLFSGRAPEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4423"/>
    <dbReference type="EnsemblBacteria" id="BAF90421">
        <property type="protein sequence ID" value="BAF90421"/>
        <property type="gene ID" value="AZC_4423"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4423"/>
    <dbReference type="eggNOG" id="COG3206">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024317_0_0_5"/>
    <dbReference type="OMA" id="DRELDNS"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="456"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="361"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="706" mass="77823" checksum="F477BB4615DBF220" modified="2007-12-04" version="1">MMISGHAGELENKAPTSWAEGRSAAFTMRDFWTAAFFHRRVVLLAALLPILVGIFACLVTKTEYTASSLLLVMVNREVATQNVTDSGPSVLSIEGLKQVESEVQIIESADVIRDAIAQIGLERLFPPGRLSFLRDLVPSGISPMDRAIERFRKNMRTTVLSGSNIVQVSVSNPNRDLAIEATDELVKAYLAYRRKIFENPTANILMVEVERFKRDLTATDNEIESLKRKAGVIDFAQDAVLAANQVDGIVQRQRQVAERKVAVAAQLEKAEQEMQALPETVFDFAQKSNASGNDDDRNILTRLLVERDRLLSQFTPSSPQVREVEQKIDTVRKTMGAPDPRLYATNRDVRNPAISYMNNMVLSLRVELDALSRQEAELNEQKQQAQGRVATLQGVETRLTELNRQRETLSEGYREYLRRAVAANVEETASKVRASNVRVVEAAGAAVTSRSMALPFLAAGVFGGLLFGAAAGAIASALRTGFITPMEVERLLGLPTLAEFADGRAPFQTVAAETAIGGLATLLLDSELDGRPLRAFHFLSQERHPDVPVFCQRLAEEFAIQRGLRTLLIDLSEPAGAHRADDGVEARGGLTIARTPVPLLWSVADSERSPLLSVRLPMVEGQRMMKELEDQFDAIIISSSASVASSVKHRLNRLVDANILIVRAEETRKAAALRLRADVLESGGVLMGFVFMGRKYYVPGWIYRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="69" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="2">Nitrate reductase delta subunit protein</fullName>
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    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF87425">
        <property type="protein sequence ID" value="BAF87425"/>
        <property type="gene ID" value="AZC_1427"/>
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    <dbReference type="KEGG" id="azc:AZC_1427"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="DMSO/NO3_reduct_chaperone"/>
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        <property type="entry name" value="TorD-like_sf"/>
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        <property type="entry name" value="Nitrate_red_del"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="1" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="235" mass="25077" checksum="A29C8EA0F51513DC" modified="2007-12-04" version="1">MMAIETLAFKALSALLSYPDAGLAAGIPEIKAALAASDLLGRDERAALAPLLEALATRDLYELQADYVELFDSSRKRSLHLFEHVHGESRDRGQAMVDLAALYEAGGLCLTANELPDYLPLFLEYLATRPLAEARGLLADTDHILALLEERLTARGSAYGAVFSAVRAIGGVAEATPITGDDAPLSRADELKALDAAWEETAVVFGPGEALDGCSVDRLRTQIRAAQRDARLATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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    <gene>
        <name evidence="11" type="ordered locus">AZC_1456</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="2 8">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1457"/>
    <dbReference type="EnsemblBacteria" id="BAF87455">
        <property type="protein sequence ID" value="BAF87455"/>
        <property type="gene ID" value="AZC_1457"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="DNA-bd_dom_put_sf"/>
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        <property type="entry name" value="Tscrpt_reg_MerR_DNA-bd"/>
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        <property type="entry name" value="MerR"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF09278">
        <property type="entry name" value="MerR-DNA-bind"/>
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        <property type="entry name" value="HTH_MERR_2"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="5">
        <location>
            <begin position="42"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="176" mass="19469" checksum="A5C4486D901FC1B9" modified="2007-12-04" version="1">MLRPLVTRGARPHLWKNAAGGSGGEMAGRARGGQSEQDEVAIGEAARRSGVKVPTIRYYEQIGLLAAPVRTEGNRRTYRSEDLSRLAFIRHARELGFEVEEIRALLTLQQDPSQSCEAADRIARGHLADVERRIASLMALKAELERMIEGCSHGRLADCKVIEVLADHGKCTHHQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX72</accession>
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        <recommendedName>
            <fullName evidence="5">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ispH</name>
        <name evidence="6" type="ordered locus">AZC_1468</name>
    </gene>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24488"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:24825"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IspH family.</text>
    </comment>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF87466">
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        <property type="gene ID" value="AZC_1468"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1468"/>
    <dbReference type="eggNOG" id="COG0761">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027486_1_0_5"/>
    <dbReference type="OMA" id="HNKYVVD"/>
    <dbReference type="OrthoDB" id="1311145at2"/>
    <dbReference type="UniPathway" id="UPA00056">
        <property type="reaction ID" value="UER00097"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:terpenoid biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="entry name" value="lytB_ispH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00191">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30426">
        <property type="entry name" value="PTHR30426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00216">
        <property type="entry name" value="ispH_lytB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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                <person name="Liu CT."/>
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                <person name="Liu C.T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1554"/>
    <dbReference type="EnsemblBacteria" id="BAF87552">
        <property type="protein sequence ID" value="BAF87552"/>
        <property type="gene ID" value="AZC_1554"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1554"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_4_5"/>
    <dbReference type="OMA" id="TLFTNWR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720757" evidence="4">
        <location>
            <begin position="36"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="87"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="558" mass="61235" checksum="DFA08C21FC36FDA6" modified="2007-12-04" version="1">MPMLSIRKRPAHRLPLTLAAALLTGCTLVSGAALAESTLRIGMTAADIPRTLGQPDQGFEGNRFTGLTMYDALVNWDLSSATKPSVLVPGLATEWKVDDADKTKWTFKLRPDVKFHDGSPFNADAVVWNVDKVLNQSAPQFDASQVGVTASRMPTLVSAKKIDDLTVELVTKEPDSFLPYNITNLFMASPTQWKKFFDAAEGADAKAKSQAAWAAFAKDASGTGPWKMSKFVPRERLELVKNTDYWDKGRVPKTDKMVLLPMPEANARTAALLAGQVDWIEAPAPDALPQLRQRGFMIRSNEQPHVWPWQFSRVEGSPWNDIRVRKAANLCVDREGMRDGLLGGLMAPATGTVEPGHPWRGNPTFQIKYDPEAGKKLMQEAGFGPSKKLTVKIQTSASGSGQMLPLPMNEYLQQALAECYFDVQLDVIEWNTLFTNWRRGAKDPSANGSNAINVTYAAMDPFFALVRFLQSGMAPPTSNNWGFINNPKFDELVKKARSTFDPAARDAALAELHAASVDDAAFLYVAHDVGPRALSPKVSGLVQPKSWFVDFSPVVVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY42</accession>
    <name>A8HY42_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170102.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1574"/>
    <dbReference type="EnsemblBacteria" id="BAF87572">
        <property type="protein sequence ID" value="BAF87572"/>
        <property type="gene ID" value="AZC_1574"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1574"/>
    <dbReference type="eggNOG" id="COG0346">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046006_6_0_5"/>
    <dbReference type="OMA" id="FIIARPG"/>
    <dbReference type="OrthoDB" id="1857145at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="133" mass="13890" checksum="E3329DEF8B2E851A" modified="2007-12-04" version="1">MFSHITVGVTDLARAGRFYDALLAPLGFNPRKTEPDGGPEALCWIGASRLPEFFAHRPFNGAPAQAGNGNMVAFLAPDPGAVDAAYVAGMAAGGTDEGPPGPRPHYGAGYYGAYLRDPDGKKVHVVHRGDVTP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYT9</accession>
    <name>HIS4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="1">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hisA</name>
        <name type="ordered locus">AZC_4499</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HisA/HisF family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173018.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HYT9"/>
    <dbReference type="SMR" id="A8HYT9"/>
    <dbReference type="STRING" id="438753.AZC_4499"/>
    <dbReference type="EnsemblBacteria" id="BAF90497">
        <property type="protein sequence ID" value="BAF90497"/>
        <property type="gene ID" value="AZC_4499"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4499"/>
    <dbReference type="eggNOG" id="COG0106">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048577_1_1_5"/>
    <dbReference type="OMA" id="EWLHLVD"/>
    <dbReference type="OrthoDB" id="794219at2"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0368">Histidine biosynthesis</keyword>
    <keyword id="KW-0413">Isomerase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000072931" description="1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <sequence length="243" mass="25313" checksum="2B7F2D47FAD59591" modified="2007-12-04" version="1">MILFPAIDLKDGLAVRLEQGDMDRATVFNRDPASQAGEFEALGFRYLHLVDLNGAFAGHPVNAAAVDRILETVSIPVQLGGGIRDMKTVDGWLEKGVTRVILGTAAVRDPDFVKAAAKAHPGRVVVGLDARDGNVAVQGWAETSNLPAVDIARRFEDAGVSAIIYTDIARDGLLKGLNMDATIALADAVSIPVIASGGLASLADVEALLEPRAKKLAGAITGRALYDGRLDPGAALALVAGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZM3</accession>
    <name>A8HZM3_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">Peptidoglycan lytic exotransglycosylase</fullName>
            <ecNumber evidence="2">4.2.2.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Murein hydrolase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4601</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Exolytic cleavage of the (1-&gt;4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.</text>
            <dbReference type="EC" id="4.2.2.n1"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="4.2.2.n1" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4601"/>
    <dbReference type="CAZy" id="GH102">
        <property type="family name" value="Glycoside Hydrolase Family 102"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90599">
        <property type="protein sequence ID" value="BAF90599"/>
        <property type="gene ID" value="AZC_4601"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4601"/>
    <dbReference type="eggNOG" id="COG2821">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037751_0_0_5"/>
    <dbReference type="OMA" id="DQNGHPY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14485">
        <property type="entry name" value="mltA_like_LT_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010611">
        <property type="entry name" value="3D_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026044">
        <property type="entry name" value="MltA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034654">
        <property type="entry name" value="MltA_3D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005300">
        <property type="entry name" value="MltA_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30124">
        <property type="entry name" value="PTHR30124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06725">
        <property type="entry name" value="3D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03562">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019422">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00925">
        <property type="entry name" value="MltA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="SSF50685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MltA" evidence="6">
        <location>
            <begin position="148"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="409" mass="43788" checksum="B62D1D09AF52B428" modified="2007-12-04" version="1">MDRSGAAFRRGRLRLAHLVRLVPVLGFLTGVPAGAAPLAPTPVPDLAGATLQPVAYGALPGWSADDQGAAFATFLASCRALAKAPAEVGPASRPRLQPALRQACAAARRLGTPNPVLARWFFEAHFRPFAITPTASPRGFLTGYYEPEVEGSLVPGADYAVPVYARPPDLISDAPGSNKGPAYRMQNGARVPYWNRAEIEDGALAGRGLEICWLKDPVDLFFMQIQGSARVRLPDGRVIRLNYDGHNGQPYVPVGRLLIERGIVPRNEMSMDRIRAFMEADPAAGKALRRESPSFVFFKAVPLKEGEGALGAQGIGLTPGRSIAVDRTLHTYGTPVFISARLPIASPAPETPFQRLMIAQDTGSAIVGPARADLFFGAGAEAGRIAGRIRDPGDFFLLLPRFEPREAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZZ5</accession>
    <name>A8HZZ5_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Putative plasmid maintenance system killer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4646</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="EnsemblBacteria" id="BAF87276">
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        <property type="match status" value="2"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="336"/>
            <end position="355"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="434"/>
            <end position="458"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
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    </feature>
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        <location>
            <begin position="525"/>
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    </feature>
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        <location>
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            <begin position="885"/>
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        <location>
            <begin position="911"/>
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    </feature>
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        <location>
            <begin position="985"/>
            <end position="1009"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87276.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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</entry>
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    <accession>A8I0U9</accession>
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        <name evidence="4" type="ordered locus">AZC_1299</name>
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        <lineage>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1299"/>
    <dbReference type="EnsemblBacteria" id="BAF87297">
        <property type="protein sequence ID" value="BAF87297"/>
        <property type="gene ID" value="AZC_1299"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1299"/>
    <dbReference type="eggNOG" id="COG3279">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000445_14_1_5"/>
    <dbReference type="OMA" id="DIHMPDF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
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        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="117"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="228" mass="24533" checksum="86C70F0414F563DD" modified="2007-12-04" version="1">MRRLLAAHGDVAILGEADNLSGAVQLISAEKPDAVFLDIDLGSSDGFQLIARLDQAPHVVFVTAHAQYAVDAFAAAAVDYLLKPVIPERLAEAIARLRRNRPPPAAGGESGGAHDILELRTPNRTVLASPAEIAALCAEGDFTRVVLADQPSLLIWRTLSHFESVLPAPPFVRLSRSLILNRDRLRSFETPSRNRSRVTLDGVGEPLVLGRAATSRLRDVVSGGTERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0Z0</accession>
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        <submittedName>
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    <organism evidence="2 3">
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169841.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1313"/>
    <dbReference type="EnsemblBacteria" id="BAF87311">
        <property type="protein sequence ID" value="BAF87311"/>
        <property type="gene ID" value="AZC_1313"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1313"/>
    <dbReference type="eggNOG" id="COG0604">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_026673_3_4_5"/>
    <dbReference type="OMA" id="RFREHWL"/>
    <dbReference type="OrthoDB" id="1027479at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="328" mass="34620" checksum="1955C0A26271968D" modified="2007-12-04" version="1">MKAVIYDAFGPADVLRLAEVPMPEVRPRDLLVKVHAAGVNRADLLQRQGYYGRQSYGESDLLGLEVAGEVVAVGHEVTDIEPGEPVMAIVGGGAYAEFARVDRGLAVRIPPALDFTGAAAVMESFVTAWEAAVHLGGTGAVTTVLVHAAAGGVGSAGVEIAHSLGARVFATANAQRRTDILNLGAECVFDYRSEDFEQGVRAATQGQGVDVIIDFVGGDYLARNLRSLALGGRLVQVGLLGGKDTAELPLSVLLHNHLRIIGTVMKSRDAEEKRAMVRRFAENALPMFTDGRLKPLVGEVFPLSEAANAHRCMEAGGGFGKIVLKVSP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I126</accession>
    <name>NHAA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nhaA</name>
        <name type="ordered locus">AZC_1326</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:29252"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169854.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I126"/>
    <dbReference type="SMR" id="A8I126"/>
    <dbReference type="STRING" id="438753.AZC_1326"/>
    <dbReference type="EnsemblBacteria" id="BAF87324">
        <property type="protein sequence ID" value="BAF87324"/>
        <property type="gene ID" value="AZC_1326"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1326"/>
    <dbReference type="eggNOG" id="COG3004">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015803_1_0_5"/>
    <dbReference type="OMA" id="MGLMLRC"/>
    <dbReference type="OrthoDB" id="1805428at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0050">Antiport</keyword>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0915">Sodium</keyword>
    <keyword id="KW-0739">Sodium transport</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000334230" description="Na(+)/H(+) antiporter NhaA">
        <location>
            <begin position="1"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <sequence length="394" mass="41186" checksum="D58CBE88EC5139DB" modified="2007-12-04" version="1">MSGPSRTQRPMSPLRAFFHHETSAGLVLMACALAAIAVANSPLAPGYFATLHAYAGPLSVQHWVNDGLMAVFFLLVGLEIKREILTGQLATWGKRTLPGVAAVGGMAIPGIVYVMLNLNNPDALRGWAIPAATDIAFALGVMSLLGSRVPSSLKIFLAALAIIDDLGAVIIIAIFYTANINVATLLGAVFVFGILRSLCAANFQDLRIYLALGAVLWVLLLVSGVHATLAGVLLALTIPITTASATPDPSRQTAPLHRLESLLHAPVAFAILPIFGFANAGVSFASITPAIMTDTLAVGVAAGLLIGKVVGIFGAVALMVRLRLAELPTHATWLQVLGVAFLCGIGFTMSLFIGLLAFEDPHMQDRVKYGILAGSLLAGVLGYGILRIAGRRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1G0</accession>
    <name>A8I1G0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1371</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Backer P.D."/>
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                <person name="Lee KB."/>
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            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170365.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1837"/>
    <dbReference type="EnsemblBacteria" id="BAF87835">
        <property type="protein sequence ID" value="BAF87835"/>
        <property type="gene ID" value="AZC_1837"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1837"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_3_5"/>
    <dbReference type="OMA" id="FFQNAWY"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="35"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="252" mass="27896" checksum="25BD3E710C4F7125" modified="2007-12-04" version="1">MDLVAEWFRNLYDTTGINLTIVYDAYDRQRFVSGVGMTIYLSVVSILISIVIGAIGAWAQGSPVRAIRALVNGFVVLFRNTPPLVQIFFFYFGLGQILPRVENDDGMMVQMISNVQWAIISLSLFAGAYNVEIFRSGLEAVPRTTSEAAEALGYTRIGVYRHVLLPLALRICLPALNNNLVNLLKTTTLAYAIAVPETLYVSKQIWNDSQNVPVMMVVLLLVYTGLVGILVYIMHRWERALAIPGYGQGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2D7</accession>
    <name>A8I2D7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1857</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170385.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1857"/>
    <dbReference type="EnsemblBacteria" id="BAF87855">
        <property type="protein sequence ID" value="BAF87855"/>
        <property type="gene ID" value="AZC_1857"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1857"/>
    <dbReference type="eggNOG" id="COG0494">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_100941_0_0_5"/>
    <dbReference type="OMA" id="FFHFYGG"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039121">
        <property type="entry name" value="NUDT19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12318">
        <property type="entry name" value="PTHR12318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="6">
        <location>
            <begin position="25"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="248" mass="27469" checksum="0284A3B7D390E13D" modified="2007-12-04" version="1">MTQPTHALAERLTAAERRQDSPNVRPRDAASLILVDRSRKAPRILMGLRHPSHRFMPNVFVFPGGRVEASDRAMPVYGMLDADSERRLMANVQRPSAQRARALAAAAIRETFEETGLLIGTTEAGAPEAPEGEWSAFAAQGVYPNLEALSFVLRAITPPRRPKRFDTRFFLADVSDVAHRVDGKVGPDSELIELRWLTVEETAKAELPTITRVVLEEVGARLAAGLPRHAPVPFYAMRRGTFVRSLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2Y7</accession>
    <name>A8I2Y7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1956</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Akiba N."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="11"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="59"/>
            <end position="66"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="342" mass="37581" checksum="0C2E2DF44DD6FC55" modified="2007-12-04" version="1">MRAPTSSPPLVEVRDLYRVFDVSKPWLNRVIEREPRRLVRAVDGVSFSIRKGETFALVGESGSGKSTIARMIAGLIPPSRGQILFDGTDISNPANAAEVKRLRRRFQMVFQDPYASLNPRFRVDAIIAEPLTAFGLATDRATVEGRVAELLRLVKLDPSVGRKFPHEFSGGQRQRIAIARALAANPDFIICDEPTSALDVSVQAQVLNLMRDLQDQFGLTYLLITHNLAVVKHMADDVGVLYLGRLGETAPARELFARPRHPYSRMLLEAIPDLSAFGRPRQAVTGEIPNPMSPPSGCTFHPRCPLVEARCRAEVPRALPAGASLVACHVVAEREAMPLPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3K7</accession>
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        <submittedName>
            <fullName evidence="10">Putative TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1626</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170154.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1626"/>
    <dbReference type="EnsemblBacteria" id="BAF87624">
        <property type="protein sequence ID" value="BAF87624"/>
        <property type="gene ID" value="AZC_1626"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1626"/>
    <dbReference type="eggNOG" id="COG4774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_9_0_5"/>
    <dbReference type="OMA" id="QTGVYFQ"/>
    <dbReference type="OrthoDB" id="173242at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721422" evidence="7">
        <location>
            <begin position="28"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="75"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="265"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="716" mass="77778" checksum="3FAD81749BF018E7" modified="2007-12-04" version="1">MRHPMSLRYLLMLGVAFSALLAGPARAQQAGETSSILLDTITVETQGQKESPTGPVQGYVARQTLTGTKTATPLLEVPQSISVITRDQMDDRQVQNLGQALDYSVGVVSQPYGTDPRFDSPIIRGFSSATSQYLNGLKLMRDAGATSIDPYALERVDVLRGPASVLYGQGNPGGLIDMISKRPTWTNFGEFNLEAGTFDNYSASFDFGGPTSPDSKVAYRLTGLARTTGTQTDFVDMDRYLLAPSFTFQPDAATSFTLLAMVQYDTPNSTVGLPAQYTLQSLNGLKLSRNTYLGDPDFNSSSRTLSSVGYEFSHTFDNNVTFRQNARYLKLDWDYAALYYNGLSTTNPAIANRGSSTNDENLGTFTIDNQLEAKLTTGPLSHDILIGADYRNFNTDTFSTFGTAPTINVFAPLYNQYIGNSIWYASKVNGTVDQLGLYAQDQIKLDRWLLTLGARQDWASTNSSTLTNYGLTTQDQDDSAATWRAGLTYLFDNGIAPYVSYSTSFEPVIGNMPAALGGAAFQPSEGKQYEAGIKYQPVGWNAFFTAAVYDLTQSNVQSTDLINGVSYAVQNGEVHVKGVELSATASLTQGLKLIANYTYMDAAITQGQYAGNQPGNVPKNSANAWLDYTWQTGPLKGFGLGGGVRYVGERYDLDSNANLLPANTLVDAAIHYEKGPFKAQLNVSNIADVTYVASCGFFGCFYGDGRTVTGKVTYKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3L4</accession>
    <name>A8I3L4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1628</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF88032.1"/>
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    <dbReference type="STRING" id="438753.AZC_2034"/>
    <dbReference type="EnsemblBacteria" id="BAF88032">
        <property type="protein sequence ID" value="BAF88032"/>
        <property type="gene ID" value="AZC_2034"/>
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    <dbReference type="eggNOG" id="COG0665">
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    <dbReference type="HOGENOM" id="CLU_007884_3_3_5"/>
    <dbReference type="OMA" id="HVNNGLA"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FAD-dep_OxRdtase"/>
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    </dbReference>
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        <property type="entry name" value="SSF51905"/>
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        <location>
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            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="426" mass="46157" checksum="1C819325AF2FCF26" modified="2007-12-04" version="1">MRFTSYWADTAPAFTGGTPGSVEGAYDVAIVGGGFTGLEAARRLAKAGARVVVLEGGSIGSGASGRNGGHLNNGLAHSYLAAKSHLGAERAATLYRAFDAAVDHIERTVAEEQIQCNFKRVGKLKLASKPAHYEGLARNFEALHREVDPDTAMLDRSAIADEVRSQAFHGGMLSRKSAVMHMGRYAAGLADAAVRHGATIFENAAVTARRREGALHVLETPRGQVSAREVLVATGAYTSGPFSWFRRRIVAVGSFIVATRPLSRAEIASVIVRERTFVTSLNIGNYFRLSPDDRLIFGGRARFSAVSDQRSDARSGEILKANLVGLFPQMSGVPLDYCWGGLVDMTQDRYPRAGRTEDGLWYAMGYSGHGAQMSNLMGRVMAEAMLGREDRNPVKGLDWPAVPGHLGTPWFLPLVGFYYKMLDRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8I740</accession>
    <name>A8I740_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">Microcystinase C</fullName>
            <shortName evidence="1">MlrC</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2076</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M81 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170603.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2076"/>
    <dbReference type="EnsemblBacteria" id="BAF88074">
        <property type="protein sequence ID" value="BAF88074"/>
        <property type="gene ID" value="AZC_2076"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2076"/>
    <dbReference type="eggNOG" id="COG5476">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028172_1_0_5"/>
    <dbReference type="OMA" id="CAAPGAM"/>
    <dbReference type="OrthoDB" id="421877at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009197">
        <property type="entry name" value="MlrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010799">
        <property type="entry name" value="MlrC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015995">
        <property type="entry name" value="MlrC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07364">
        <property type="entry name" value="DUF1485"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MlrC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UCP012702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1485" evidence="3">
        <location>
            <begin position="3"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="MlrC_C" evidence="2">
        <location>
            <begin position="306"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="498" mass="52380" checksum="EDA084B41F57CC23" modified="2007-12-04" version="1">MTRIAVGGFMHETNTFAPAQAPYAAFEHGGGFPPISRGAEIFERMPGKNTGLSGFIAAAAEKGWEVLPTLWCAAAPSAHVTEDAFERIMAEMLERLAAFGPVDGVYLDLHGAMVTTHYDDGEGETEARVRDLIGPDVPLVVSLDLHGNVSRRMVDEADALVAYRTYPHVDMADTGRRAADVLADRMAGKPFAKAFRQIPFLMPIAWQCTEMEPCRTLYQQLAQIEREMGLVHLSFLPGFPAADFPDCGGSVVAYADTQAKADAAADAMTALILAQEDAFAGSAFSPEAGVREAMAIAATAKKPVVISDTQDNPGAGGTSDTTGMLRALLACGAERAALGLMVDPQAADAAHAAGVGGQVTLALGGKSGLPGDAPFEGTFTVEALSDGTFNATGPYFGKGPMFLGRSACLRIGGVRVVVASRKAQLADQAMFRYVGIEPTEQAILVNKSSVHFRADFTPIAETILVCTAPGAMPLSPASLPWKHLRPGVRLEPNGPAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7F6</accession>
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            <fullName evidence="3">Hydantoin utilization protein B</fullName>
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    </protein>
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        <name evidence="3" type="ordered locus">AZC_2116</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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    <reference evidence="3 4" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2116"/>
    <dbReference type="EnsemblBacteria" id="BAF88114">
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        <property type="gene ID" value="AZC_2116"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2116"/>
    <dbReference type="eggNOG" id="COG0146">
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    <dbReference type="HOGENOM" id="CLU_020413_1_0_5"/>
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    <dbReference type="OrthoDB" id="1018930at2"/>
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        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
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        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="5"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
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        </location>
    </feature>
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        <location>
            <begin position="524"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="570" mass="60567" checksum="8873BCAAC05DD55B" modified="2007-12-04" version="1">MTAIDPVTLAVLKGRLEQIADEMDATLYRSAFNPIIAEARDACHGLYHAETGDTLVQGTKGLPIFVGAMAFAVRAVIEKVARDGDLQPGDSFLFNDPYAGGTHLNDFRLVRPIFRGGKLYCWLASVGHWLDIGGNVPGGFNARATESFQEGVRIPPVKLFKAGVLNHDIIEILSANSRVPVSNYGDLNGQLNALDLGERRLAELLDAYGENIVAQAFDAFSDRAEAMMRAAIRALPDGIYSFEDYLDNDGITPDRLTIALDLTVDGEKMTLDFSRSSAPCAGPLNIAYSTAAACCYVALKHVFTDVPANAGCLRPITFVIPETTLLGVKPPKPVGGYTETILRVIGVVFGALAKADPARATAAPFGTINALSLAGHRPDGSRWVMFSFFGGGLGGNPESDGLSHANNPISMATIPPAEILEAAYPVLFTQWALRPDSAGAGAHRGGLGAVYEIEPLTDADVFLLGERGIYPPFGVAGGTPAALNVFSWETEDGERSPPLASKVTDVKVRAGQRVRLETPGGGGYGDPKDRKREDVERDVRQGLVSVEAARTLYGVEITPDTTIPAQGAAA</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2681"/>
    <dbReference type="EnsemblBacteria" id="BAF88679">
        <property type="protein sequence ID" value="BAF88679"/>
        <property type="gene ID" value="AZC_2681"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2681"/>
    <dbReference type="eggNOG" id="COG0765">
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    <dbReference type="HOGENOM" id="CLU_019602_1_0_5"/>
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    <dbReference type="OrthoDB" id="1523519at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
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    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
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    </dbReference>
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        <property type="entry name" value="SSF161098"/>
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        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="151"/>
            <end position="170"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="212"/>
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    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="21"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="224" mass="24688" checksum="BF7D6AA9A2DB19E4" modified="2007-12-04" version="1">MSYTLQFGQIWPYLPRLLEGAVISLQIAVLAFCGGLFIGTLCAAIRSFGPRWLARIVGVYVVFFTNTPQLVQIYFLYFALPDSGILLSSFAAVVIGMTLNAGAYLTEIQRAGFESRRVSEMEAAEVMGFSRLQQIRYVILPHVARVLFPPLSNQFIIVTLGTSMAAVFGVEELTGEAFNINSQTFRSIEIFSVTAGIYVVLTLAASLLLAFAGRTFFRARTELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <comment type="subcellular location">
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    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
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        <location>
            <begin position="78"/>
            <end position="181"/>
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            <end position="714"/>
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        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="719" mass="77868" checksum="545610333706B30C" modified="2007-12-04" version="1">MKGDTMPPRAHASRAQGAVLALAATLPLADAARAQSAPPETTTIALDTLDVSAQPLGDGLNLLVPSMTGSRLDLTPLQTPSSVQIIPGEIARERGQYTVIEAVTQDAAGFSASPAPGNGGTSLSTRGFSGHGSVMQLYDGTRLYVGAGTVTFPFDTWSAERIEVLRGPASVLYGDGAIGGVVNVVPRKPDPLSSHGEALMAVDSLMSGRLALDATGPINDRVSYRFDIAGKLSDGWVDRGDNGSLAVSAAVRIQASDTLVLSLSNDYGYQEPQKYFGTPLINGQFTGLLRNQNYNVGDAAISYSDNWSQFKAEWTPSDALTVRSTFYYLTSDRHWRDSETYAFQPATGLVRRSDYIEIMHDQSQLGNRTDATWRGSILGFANEVVVGFDINSIDFTHTNNSPYRGSSSVPLIGFNPGTFASPDPTVPKYHTDTTQYSLFAEDRLVLDEHWSIVGGLRWENPTITRTNLVTAQEEFQKSYSAVTGRIGVIYSPVQDLSLYASYTTGIDPVAGLITLSSANANFNLTTAEQYEAGIKQVFWGGRGEWTFAVYDITKYNLLARSSANSQVTEQIGQQSSRGVEGTVSVSFLENWRISANLALLDARYDNYITTGGINATGNTPVGVPEQVGNVWLTWNFAPKWKTWAGLQYVGPVFVNEANTVQRPEYYVVNGGLQWAPTPAANITLRVYNLFDETYAVAGNTGQWVLGQPRTVELSSSVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8W0</accession>
    <name>A8I8W0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol uptake facilitator protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2711</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171235.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2711"/>
    <dbReference type="EnsemblBacteria" id="BAF88709">
        <property type="protein sequence ID" value="BAF88709"/>
        <property type="gene ID" value="AZC_2711"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2711"/>
    <dbReference type="eggNOG" id="COG0580">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_020019_9_2_5"/>
    <dbReference type="OMA" id="ACFPGRK"/>
    <dbReference type="OrthoDB" id="1744995at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="241" mass="24703" checksum="D07402E6D45E2D0B" modified="2007-12-04" version="1">MHTPFTGELLGTLVLILLGDGVVAGVLLNHSKAQNSGWIVITAGWAFAVMAGVFTSAATGSPDAHLNPAVTLGFAIVSGDYSKLAVYIPAQLIGAFLGATLVWLQYLPHWSKTPDQGLKLAIFCTGPAIRNAPANLISEIIGTVVLLFVIAAIFSKPVMGAGIPSTLGPYMVGILVWAIGLSLGGTTGYAINPARDLGPRIAHAVLPVAGKGGSDWGYSWIPVVGPLAGAVVAGLLIKAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8X1</accession>
    <name>A8I8X1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171239.1">
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171027.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2501"/>
    <dbReference type="EnsemblBacteria" id="BAF88499">
        <property type="protein sequence ID" value="BAF88499"/>
        <property type="gene ID" value="AZC_2501"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2501"/>
    <dbReference type="eggNOG" id="COG1024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009834_7_3_5"/>
    <dbReference type="OMA" id="EMFMPAA"/>
    <dbReference type="OrthoDB" id="1498685at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="261" mass="27206" checksum="423768922EFFFCBA" modified="2007-12-04" version="1">MSATLLYEATEGLARITIAQDAKMNAMTFEMWSALPGLISRAAADPAIRAIVLTGAGEKAFCAGADISQFGARRSDPEAVAAYDHAVAAGMTALAGAEKPTVALIRGICFGGGFGLALACDIRLARADARFRVPAARLGLGYGYEGVKLISRKLGPDATADILFSARILDAAEAERLGVVARAWAAEAFETESAAYLGQIAANAPLTLVAAKRALVELARPEAERDLDAVAARVAACFASADYREGQAAFKEKRPPRFTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAW2</accession>
    <name>A8IAW2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein HflC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflC</name>
        <name evidence="5" type="ordered locus">AZC_2570</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">HflC and HflK could regulate a protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the band 7/mec-2 family. HflC subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171094.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2570"/>
    <dbReference type="MEROPS" id="I87.001"/>
    <dbReference type="EnsemblBacteria" id="BAF88568">
        <property type="protein sequence ID" value="BAF88568"/>
        <property type="gene ID" value="AZC_2570"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2570"/>
    <dbReference type="eggNOG" id="COG0330">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_059167_1_0_5"/>
    <dbReference type="OMA" id="DFFAFYR"/>
    <dbReference type="OrthoDB" id="1714999at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052547">
        <property type="term" value="P:regulation of peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03405">
        <property type="entry name" value="SPFH_HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010200">
        <property type="entry name" value="HflC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911">
        <property type="entry name" value="PTHR42911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005651">
        <property type="entry name" value="HflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01932">
        <property type="entry name" value="hflC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="4">
        <location>
            <begin position="23"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="286"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR005651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="310" mass="34509" checksum="A019430084B10702" modified="2007-12-04" version="1">MKNSFLGGGILVVFLIVVIGLYSSAFTVTQNQQALVLRLGNPRPPITTPGLHWKVPFIDTVVYLDKRILDLENPSQEVIASDQKRLVVDAFARYRISDPLKYYQAVGTVEGANSRLATVLNSALRRVLGESTFTQVVRDEREGLMARIKEQVNREASNFGITVVDVRIRRADLPDANSQAVFQRMQTERQREAAEIRAQGGEAAQRTRSRADREVTILLAEANSRGEAVRGQGDAERNQIFAQAYGRDPEFFTFYRSLQAYEQSIKASDTRLVLSPEADFFRFLRNPQGTRGPVGAAPADSVTPVPVPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB48</accession>
    <name>A8IB48_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YjgF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2609</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
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                <person name="Lee KB."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3106"/>
    <dbReference type="EnsemblBacteria" id="BAF89104">
        <property type="protein sequence ID" value="BAF89104"/>
        <property type="gene ID" value="AZC_3106"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3106"/>
    <dbReference type="eggNOG" id="COG1117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="TIDICRV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="31"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="277" mass="30587" checksum="F7897905859A3859" modified="2007-12-04" version="1">MSIHPPLGPEVSLPPLALSGLAPEAPASVKMEARHITYHYGRTLALNDVSVPVHRDRVTAFIGPSGCGKSTLLRVFNRMYDLYFDQTVDGEVWMDGENILAPNVDLLALRTRIGMVFQKPTPFPLSIFDNVALGVRLSLDPAPAELRNRVEEALRRAALWDEVKDILPTSALSLSGGQQQRLCIARTLAVGPEVILFDEPCSALDPIATAKIEQTIDELKRDHTIAIVTHNLQQAARISDYTAFMYLGEILEFGTTRHLFTAPADARTQRYITGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBW3</accession>
    <name>A8IBW3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="13 14 15">UvrABC system protein B</fullName>
            <shortName evidence="14">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uvrB</name>
        <name evidence="20" type="ordered locus">AZC_3127</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 14">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12 14 15">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="14">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 14 15">Belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171651.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3127"/>
    <dbReference type="EnsemblBacteria" id="BAF89125">
        <property type="protein sequence ID" value="BAF89125"/>
        <property type="gene ID" value="AZC_3127"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3127"/>
    <dbReference type="eggNOG" id="COG0556">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009621_1_1_5"/>
    <dbReference type="OMA" id="EYVDRMV"/>
    <dbReference type="OrthoDB" id="95696at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 14 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 14 15" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 14 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 14 15" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="111"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="516"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="17">
        <location>
            <begin position="709"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="752"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="14">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="754"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="124"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
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    </evidence>
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            <dbReference type="ARBA" id="ARBA00023204"/>
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    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="BAF89125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="876" mass="97179" checksum="57E7C6C8C7E440A4" modified="2007-12-04" version="1">MAKASRPGKLGERSQRHFEPAPAQPLDPALAQSLGLNPGDLSVDFESSGASATVQALSQLIENGRPEVNGQTWVPHRPPRPEKSEGGIRFVMKSDFQPSGDQPQAIKELTEAARQGERDQVLLGVTGSGKTFTMAKVIETLQRPAIVLAPNKTLAAQLYGEFKSFFPDNAVEYFVSYYDYYQPEAYVPRTDTYIEKESSINEQIDRMRHAATRSLLERDDVIIVASVSCIYGIGSVETYASMTFKLEVGERIDQRQLLADLVALQYKRIQSDFARGTFRVRGDVVEIFPAHYEDRAWRISLFGDEVESIVEFDPLTGHKTGDMKSVKVYASSHYVTPRPTLIQAITGIKAELKHRLDELYKMGRLLEAQRLEQRTRYDIEMMEATGSCAGIENYSRWLTGRKPGEPPPTLFEYVPDDAMVFIDESHVTVPQIGAMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPQTVHVSATPGPWEMDRTGGVFVEQVIRPTGLIDPPVDIRPARTQVDDLLGEVRATAAKGYRSLVTVLTKRMAEDLTEYLHENGIRVRYMHSDIDTIERIEIIRDLRLGAFDVLIGINLLREGLDIPECGLVAILDADKEGFLRSETSLIQTIGRAARNVDGRVILYADHETGSMKRAMAETARRREKQIAYNTEHGITPESVKKAIGDILNSVYERDHVAVDSGLAEEGAAFGHNLKAIMADLEKRMRAAAADLDFEEAARLRDEIKRLQATELAVSDDPMARQEAVDDRTGGFRGPRKYGKAANLPAAAAKGKGRARAPAKPADDAGIGEEQSRYAPDTGSRAGPPEMPLYAARPAARAAKPSLDDMGPGTDRAEPLGAADFRPGPRPDPGTKGYRKGGRRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC57</accession>
    <name>A8IC57_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3164"/>
    <dbReference type="EnsemblBacteria" id="BAF89162">
        <property type="protein sequence ID" value="BAF89162"/>
        <property type="gene ID" value="AZC_3164"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3164"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_1_2_5"/>
    <dbReference type="OMA" id="MIPHLAI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="82"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="277" mass="29181" checksum="6FCAC1BF80B76E62" modified="2007-12-04" version="1">MTLSQAETFSGAAGRAAATPRRTTGWRRWRFALGLLLPVGLALVWEFAVRSGLAQGRLLPPPSRIAEALYGLARSGELAPHIAATLQRIAAGFALGVVAGTALGALSGASGLARTIVDPTLQGLRAIPSIAWVPLFILWLGIFEASKVTLIAVGVFFPVYLGTLGAVMAVDRKIIEVGQVFLFSGPTMVRRILLPAILPHYVTALRAGLGLGWMFVVAAEFMGASEGLGYLLLDGQQLGKPDQIVAAILVFAVLGKATDTLLLTLTRPLLKGYDLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICA7</accession>
    <name>A8ICA7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">marR</name>
        <name evidence="2" type="ordered locus">AZC_3183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171707.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3183"/>
    <dbReference type="EnsemblBacteria" id="BAF89181">
        <property type="protein sequence ID" value="BAF89181"/>
        <property type="gene ID" value="AZC_3183"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3183"/>
    <dbReference type="eggNOG" id="COG1846">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_083287_27_2_5"/>
    <dbReference type="OMA" id="HEQWVVE"/>
    <dbReference type="OrthoDB" id="1744037at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023187">
        <property type="entry name" value="Tscrpt_reg_MarR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01117">
        <property type="entry name" value="HTH_MARR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="171" mass="19274" checksum="802B3271F609ECD0" modified="2007-12-04" version="1">MTEPMPEDFEALVRDEPAGSKMELRLWLRLLSVSNLVSAEIRRRLRAEFDVTLPRFDVLAQLNREPDGLRLGDLSRRMMVSNGNITGLIDRLVEEGLVVRKVDPNDRRAATVRLSRAGATMFRIMASAHEAWIHELFGDLSKRQVAGLLDELETLKRSVAGVVHATEADRS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICV0</accession>
    <name>GATB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatB</name>
        <name type="ordered locus">AZC_2847</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171371.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ICV0"/>
    <dbReference type="SMR" id="A8ICV0"/>
    <dbReference type="STRING" id="438753.AZC_2847"/>
    <dbReference type="EnsemblBacteria" id="BAF88845">
        <property type="protein sequence ID" value="BAF88845"/>
        <property type="gene ID" value="AZC_2847"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2847"/>
    <dbReference type="eggNOG" id="COG0064">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019240_0_0_5"/>
    <dbReference type="OMA" id="ARKWWMG"/>
    <dbReference type="OrthoDB" id="497127at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000095181" description="Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B">
        <location>
            <begin position="1"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <sequence length="492" mass="53862" checksum="B624C18F01152346" modified="2007-12-04" version="1">MTAHVRPTDAKKLIKGATGNWEVVIGMEIHAQVSSNAKLFSGASTAFGGPPNDHVSLVDAAMPGMLPVINKECVAQAVRTGLGLRAQINLRSTFDRKNYFYPDLPQGYQISQYKSPIVGEGEVIVDLLDGESFVVGIERLHLEQDAGKSIHDLSPTLSFVDLNRSGVALMEIVSRPDLRSSEEARAYVTKLRSILRYLGTCDGDMEKGNLRADVNVSVRRPGEPLGTRCEIKNVNSIRFIGQAIEVEARRQIEILEDGGVIDQETRLFDPNKGETRSMRSKEEAHDYRYFPDPDLLPLVLHADFVEELKSHLPELPDEKKARFIADYGLSPYDASVLVAERDTADYFEQVAKGRDGKAAANFVINELFGRLNKDGKDVITSPVSPAQVAAIVDLIGEGVISSKIAKDLFEIVYTEGGDPRVLVEERGLKQVTDTGAIEKVVDEIIAANPDKVAQVQAKPTMLGWFVGQAMKASGGKANPQALNDILKRKLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDG7</accession>
    <name>A8IDG7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon monoxide dehydrogenase medium subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2937</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2937"/>
    <dbReference type="EnsemblBacteria" id="BAF88935">
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        <property type="gene ID" value="AZC_2937"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2937"/>
    <dbReference type="eggNOG" id="COG1319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058050_3_0_5"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:oxidoreductase activity"/>
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        <property type="entry name" value="CO_DH_flav_C"/>
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        <property type="entry name" value="CO_deh_flav_C"/>
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        <property type="entry name" value="FAD_PCMH"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="280" mass="29139" checksum="369043C9F2BFFC24" modified="2007-12-04" version="1">MPDIEAGRASGDQTMYAFDYQRPAALDDAIGLLRSVNEPKVLAGGQTLLPTLKQRLAQPGTLVDLSRIPGLSRIERQGEGLVIGAMARHAEVATSALVKSVIPALAELAGVIGDPAVRNRGTLGGSIANNDPTADYPAGCLGLGATILTSKRALAADDFFTGLFETALEDDELVVGVEFPAPARAGYAKFRNPASRYAMAGVFVAQGAEGVRVAVTGAGQGGVFRWSEAEEALAADFRPEALDGLSVDSADMMSDLHGSADYRAHLVKVMARRAVVASMG</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDN2</accession>
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        <recommendedName>
            <fullName evidence="2">Glutamate--cysteine ligase</fullName>
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        <name evidence="4" type="ordered locus">AZC_2967</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012171491.1">
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        <property type="gene ID" value="AZC_2967"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="DYVEWAL"/>
    <dbReference type="OrthoDB" id="991285at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="GCL_bact_plant"/>
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    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
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    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011556">
        <property type="entry name" value="Glut_cys_lig_pln_type"/>
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    <dbReference type="PANTHER" id="PTHR34378">
        <property type="entry name" value="PTHR34378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017901">
        <property type="entry name" value="GCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01436">
        <property type="entry name" value="glu_cys_lig_pln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="114"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR017901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR017901-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="456" mass="50476" checksum="F98D2B287564F4CE" modified="2007-12-04" version="1">MARDTTDATPIRSRDELVAYLEAGNKPEAAFRIGTEHEKIPFTLGRHEPVPYEGDKGIRAILEGMRDVLGWDPIMEGPTIIGLADPRAGGAISLEPGGQFELSGAPLASIHETCSELNTHLAQLRTVAEPLGVGFLGLGMSPKWSRAETPVMPKGRYKIMSGYMPKVGKLGLDMMFRTCTVQVNLDFSSEADMVQKLRVSLALQPIATALFANSPFTEGRPNGFLTFRSEIWRDTDNARSGMLPFAFEDGMGFERYVDYALDVPMYFIKRGDAYIDVAGSSFRDLLAGRHPAVPGETATLADWINHLSTIFPEVRLKRYLEMRGADAGPWAKLCALPAFWVGLLYDRQSLDAAWQLAKDWTADERQTLRDEVPRLGLKATIGGRTVQDIARDLLALSRAGLVRRRQLDSQGRDETRFLAPLEEVVATGRTPADDLLSRYHGAWQGSVEPVFEELAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDQ1</accession>
    <name>A8IDQ1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative sterol carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171499.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2975"/>
    <dbReference type="EnsemblBacteria" id="BAF88973">
        <property type="protein sequence ID" value="BAF88973"/>
        <property type="gene ID" value="AZC_2975"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2975"/>
    <dbReference type="eggNOG" id="COG3255">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_105945_2_0_5"/>
    <dbReference type="OMA" id="CTIKISA"/>
    <dbReference type="OrthoDB" id="1982614at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003033">
        <property type="entry name" value="SCP2_sterol-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02036">
        <property type="entry name" value="SCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SCP2" evidence="1">
        <location>
            <begin position="9"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="102" mass="10553" checksum="C1497505B0BA9A18" modified="2007-12-04" version="1">MAEIATLIDALEERASALSALNHTVRFDLTDSGQSIHLDATGGGVSVTESDAEAEAVLKLSSDTLDKLITGRIGPMLAFSTGRLRLEGSQGVALKLAGLLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDT0</accession>
    <name>A8IDT0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2988</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171512.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2988"/>
    <dbReference type="EnsemblBacteria" id="BAF88986">
        <property type="protein sequence ID" value="BAF88986"/>
        <property type="gene ID" value="AZC_2988"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2988"/>
    <dbReference type="eggNOG" id="COG0577">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_035316_0_0_5"/>
    <dbReference type="OMA" id="DSHRGYR"/>
    <dbReference type="OrthoDB" id="768211at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="339"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="9">
        <location>
            <begin position="325"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="424" mass="44249" checksum="C450DC98D70C478A" modified="2007-12-04" version="1">MFRFIAADLRRQWIGVLAVTLIIALAVALGVVVTLQERALRLGSARAAQAFDLVLGAPGSETQLVLSAIFLQPAPLPLMSGEVLAGLVADPRVAWAAPVGFGDFVDDYPIVGTTQPLIDGLTKMTEGRSFARLDEAVVGAAVPKALGAAFHPMHGQVGGPAEVHGRITYRVVGRLAPTGTPWDRAVLVPIEAVWRVHGAEAATGHADHDAPETGRPRSLADAHQAHRDMAPDLDDAINPDAIAAPGAPGLPAIVVKPKTIADAYKLRRDYRSDHSLAVFPGEVLTRLYATLGDARQVIALVAVGAQVLVGAAILLVVVIHVLQRRKQIGALRAFGAPRLAVFGIVWLEVLALLATGLVAGFAIGYAAARLISRTLEQASGIALPVAFLPGDATALALLFAVGGLVALIPALLAYRQSPAQALRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
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    <gene>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171559.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF89033">
        <property type="protein sequence ID" value="BAF89033"/>
        <property type="gene ID" value="AZC_3035"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3035"/>
    <dbReference type="HOGENOM" id="CLU_2314368_0_0_5"/>
    <dbReference type="OrthoDB" id="2165401at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="99" mass="10620" checksum="940A477A33907622" modified="2007-12-04" version="1">MTVHIGTLGEIPTTALKAPSPHRRAPNWGAFLARPIPLADGERVLERLWDAADVLHAEAGESPDAAEKALIAAAQSGERGDISDATDSLEIYLRRRALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEA5</accession>
    <name>A8IEA5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fkbM</name>
        <name evidence="2" type="ordered locus">AZC_3468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171991.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3468"/>
    <dbReference type="EnsemblBacteria" id="BAF89466">
        <property type="protein sequence ID" value="BAF89466"/>
        <property type="gene ID" value="AZC_3468"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3468"/>
    <dbReference type="eggNOG" id="COG1086">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048284_0_0_5"/>
    <dbReference type="OMA" id="GWAETIM"/>
    <dbReference type="OrthoDB" id="1340956at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="232"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="409" mass="44681" checksum="EC93C98BD396C374" modified="2007-12-04" version="1">MPRRAAARRLKLVSNALVGRHFEALPDAAVARDLLRVANSRAPAGVPILPRARPLWLFGAGPLGKEARRYFESVGQPVAGVIDSDADACADDPDWADLPVRGPEAVPELQRAKALLAIAVIDRPYVPLEAELNRQGWSQCVPLYDVTEAFRDQHPLSNGWFASPLSEVELAAADEILAGFADDASRAHYLRFAAWRLARQEWDFEGASVEPDARFFIPEITSVLKGDERFLDAGAYHGEVTARLLQATNASVSTVWAIEPDVANRSVLQAYVSSLDVTLQARIQVLDAVLGARTEAVRFQEGLGHASQIAPTGKILRACAPLDALSLDPTFVKLHLEGAELAALNGARETLRRRRPIVAAAVYHDAAGLLGTPQWFMRHLPDYTILMRTHDWCGMGAIVYALPKERVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8IER9</accession>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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    <gene>
        <name evidence="1" type="ordered locus">AZC_3527</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="BAF86151">
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    <dbReference type="KEGG" id="azc:AZC_0153"/>
    <dbReference type="eggNOG" id="COG4645">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_041000_2_0_5"/>
    <dbReference type="OMA" id="LEIFCLG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014550">
        <property type="entry name" value="UCP028704_OpgC"/>
    </dbReference>
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        <property type="entry name" value="PTHR38592"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF10129">
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    </dbReference>
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        <property type="entry name" value="UPC028704"/>
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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        <location>
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            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="403" mass="44789" checksum="7F1450323CC009B2" modified="2007-12-04" version="1">MAEPRRARGEGARTGTVVRLPVRARPAPAPRDLRLDFFRGLALWLIFLDHVPTNVLNMVTLRNFGFSDASEIFVFISGYTAAMVYGRVMHERGFVIASARALKRAWQLYVAFVFLFVVFLAQISYVAGRFNNPLYAEETNVLRFLDEPDVTLIQALLLRFKPANTDILPLYILLMAALPLVLAGLLRRPNLTLGLSVALYAVTRAMGWNLPGWPEEHVWLFNPLAWQLLFVFAGWCAIGGSERLEPVLRSRVAVVAAGLFLVVSAVVVLSWSVPALDGVVPEELGELIYPISKTDMSLLRFFHFLALALVVVHFVPRDWRGLTSPLARPLVLCGQHSLEIFCLGVFLSFGAHLVLVEVSGRLWVHMAVSLAGIAIMVALAAVMSWYHENEKRRGPERPPGGPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH29</accession>
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        <submittedName>
            <fullName evidence="6">Response regulator</fullName>
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        <name evidence="6" type="ordered locus">AZC_0166</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168697.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0166"/>
    <dbReference type="EnsemblBacteria" id="BAF86164">
        <property type="protein sequence ID" value="BAF86164"/>
        <property type="gene ID" value="AZC_0166"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0166"/>
    <dbReference type="eggNOG" id="COG0745">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_30_4_5"/>
    <dbReference type="OMA" id="VWGWDFG"/>
    <dbReference type="OrthoDB" id="817710at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
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        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="137"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="137"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="245" mass="26868" checksum="2F0170AF1D1D726A" modified="2007-12-04" version="1">MSQGASATTLLIVEDDREIRSLLADFLGREGYDTRLAADGRAMDAILAGIRPDLVILDIMLPGEDGLSLCRRLRAQGDVPVLMLTAKGDEVDRIVGLEVGADDYLVKPFNPRELLARIRAILRRVQAAARVGEDPRRQDIAFGGLIADLDARSVRTPDGIALDLTSAEFDLLACFLERPRRVLSRDQLLDWTRGRSADPFDRTIDVAVSRLRRRLSLVAPEAAQLIKTVRNGGYIFALPPGGKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
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        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0175</name>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168706.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0175"/>
    <dbReference type="EnsemblBacteria" id="BAF86173">
        <property type="protein sequence ID" value="BAF86173"/>
        <property type="gene ID" value="AZC_0175"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0175"/>
    <dbReference type="eggNOG" id="COG1995">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040168_1_0_5"/>
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        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
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        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="341" mass="35912" checksum="45B1CF51587D2B90" modified="2007-12-04" version="1">MTPHLAITMGDPAGIGPEIIAKACERLKDRLASGHLRLLVIGSNAALHGAQKALGSTVAIPEVSADDAEWPALACLQACPEGEPILPGVASVDGGRFAYHAVERGVRLAQAGRIQGIVTGPLNKETLNRAGFHYAGHTEMLAELTGARGSVMLLAHGNMRVSHVTTHVALKDVPKRLTPERLRYVIERTDEALRGLGLERRRIAVAALNPHAGEGGLFGTEDMDVSEPTIAKAVADGFDVVGPVPGDTVFVKLRGGQFDAVIAMYHDQGHIPVKLLGFNVNPETGKWDALSGVNITLGLPIIRTSVDHGTAFDIAGKGIANELSLIEAIEYAEKLAASRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHG9</accession>
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        <submittedName>
            <fullName evidence="2">Twin-arginine translocation pathway signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171797.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3274"/>
    <dbReference type="EnsemblBacteria" id="BAF89272">
        <property type="protein sequence ID" value="BAF89272"/>
        <property type="gene ID" value="AZC_3274"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3274"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013917_0_1_5"/>
    <dbReference type="OMA" id="MRISGQS"/>
    <dbReference type="OrthoDB" id="337328at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012368">
        <property type="entry name" value="OxRdtase_Mopterin-bd_su_IorB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036389">
        <property type="entry name" value="IOR_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="213"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="728" mass="77992" checksum="60A0733D8CBDB2E5" modified="2007-12-04" version="1">MTHSSQISSSALSRRGFLRGGAVAAGAFTFGFSFPALKPALAQTAPNEVNAWVVVQPDETVIIRIARIEMGQGALTGLAQLVAEELDCDWDKVRFELVNPGSNKSRGNAWRSQQTGGSRSIRGSHDYLRLGGAQARAMLVEAAARSWNVPAAQCRAAKGVITHAASGRTITYGAVATAANAVPVPADVPLKDPKDWTIAGKPLKRLDTLDKLNGSLVYGMDIRMPGMLVAIPKACPVQGGKVKSFDAAAVSGMRGVKHVLKVDDETVAVVADTFWRAKTALDALPIQWDEGPNAKVSSATIAATLREGLSAPDAFVGHKAGDAKAVLGKASRVIEADYGFPYQNHAPMEVLSATVRWTADRCEAWAPTQSPEAAHATLATAAGLSPDKCEVNVMRIGGSFGRRLATDYLRIATLIAKQVPGVPVKMMWTREEDMLQGRFHPVTQARFRATLDGQGNVEALHMRISGQSIASYAIPSLVGNNGDPLVYQGLLPDGPEGRLGYTIPNILIDYAMRNPHIRPGFWRGVNLNQNAVYMESFIDELAHAARQDPLEFRRRLMKNHPKHLAVLEAAARGIGWGEKPAAGRARGLAQIMGFGSYVAAAAEVSVTKGQLRIHRIVAATDPGYVVNPQQVEAQVAGSFVYGLSAMLYGECTVKDGRIEQENFDTYNVMRLDEMPEVEVISMPSGGFWGGVGEPTIAVAAPAVLNAIYAATGKRVRQLPLKNVDLNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHM2</accession>
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        <submittedName>
            <fullName evidence="5">Regulatory protein</fullName>
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    <gene>
        <name evidence="5" type="primary">gntR</name>
        <name evidence="5" type="ordered locus">AZC_3296</name>
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    <organism evidence="5 6">
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
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        <cofactor evidence="2 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
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    <comment type="similarity">
        <text evidence="4 11">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF89409">
        <property type="protein sequence ID" value="BAF89409"/>
        <property type="gene ID" value="AZC_3411"/>
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    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_003433_0_0_5"/>
    <dbReference type="OMA" id="ANFSFEF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="Gene3D" id="3.90.1150.10">
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    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017772">
        <property type="entry name" value="Cys_deSase_NifS_bac/arc"/>
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    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
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    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
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        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
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    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
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    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03402">
        <property type="entry name" value="FeS_nifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="12">
        <location>
            <begin position="3"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00001357"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031911"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF89409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="383" mass="40360" checksum="63071D9F2A53DCA6" modified="2007-12-04" version="1">MPIYLDNNATTRVDPAVVAAMLPFFTEQFGNASSSHAFGSSVAESVRAARRSLQALIGAAFDHEIVFTSGGTESDNTAILSALATQEGRDEIVTSAVEHPAVLNLLDHLEATRGITVHRIGVDGEGRLDLEAFARALSPRTALATIMWANNETGTLFPVAQLAQMARAVGALFHTDAVQAVGKIPIDLAATQIDMLSLSGHKLHGPKGIGALYLRKGTPFAPLVRGGPQERRRRGGTENVPGIVGLGAAAALALEELPEEQGRVRALRDRLEQGVLQQAGPCRALGVPDGRLPNTTNIAFEHLEGEAVLHNLNKAGIAASLGSACASGSMEPSHVLKAMQVPASALRGAIRFSLSRDNTDDDVDRVLQVLPEITARLRSTVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIK3</accession>
    <name>A8IIK3_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3417</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171940.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3417"/>
    <dbReference type="EnsemblBacteria" id="BAF89415">
        <property type="protein sequence ID" value="BAF89415"/>
        <property type="gene ID" value="AZC_3417"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3417"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_114962_0_0_5"/>
    <dbReference type="OMA" id="YRFYFYK"/>
    <dbReference type="OrthoDB" id="1817403at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="189" mass="20415" checksum="40310FB9C420A717" modified="2007-12-04" version="1">MHTARDTSGSRTLTGAGAPVSDGFEDALLSDPLLGGGLPEDAEAHLHAASLAYADGAVAEAHLKAAQGLAPGHVAVLIGLYRFYFYKGRLAEALEVSKECLIKSARDNNFSTDWRDVHAGDADFGRYESLKPRFFLFSLKGYAYLQMRLGELEEGRAAATKLMQLDPSDKIGARVLLDILDRAEQDDDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIX0</accession>
    <name>A8IIX0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168741.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86208">
        <property type="protein sequence ID" value="BAF86208"/>
        <property type="gene ID" value="AZC_0210"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0210"/>
    <dbReference type="HOGENOM" id="CLU_2766949_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="69" mass="7203" checksum="F5D8F7F9684C88C4" modified="2007-12-04" version="1">MTVHFAGEQPTVPQAAAWSAATLGAGEAYEAACLAQAAGISREEAMGLVRRHGTHRATLMAAARRLKRG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ80</accession>
    <name>GPDA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycerol-3-phosphate dehydrogenase [NAD(P)+]</fullName>
            <ecNumber evidence="1">1.1.1.94</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">NAD(P)H-dependent glycerol-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gpsA</name>
        <name type="ordered locus">AZC_0263</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:11092"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168794.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IJ80"/>
    <dbReference type="SMR" id="A8IJ80"/>
    <dbReference type="STRING" id="438753.AZC_0263"/>
    <dbReference type="EnsemblBacteria" id="BAF86261">
        <property type="protein sequence ID" value="BAF86261"/>
        <property type="gene ID" value="AZC_0263"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0263"/>
    <dbReference type="eggNOG" id="COG0240">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033449_0_2_5"/>
    <dbReference type="OMA" id="NRMFGNM"/>
    <dbReference type="OrthoDB" id="1419877at2"/>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046167">
        <property type="term" value="P:glycerol-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006650">
        <property type="term" value="P:glycerophospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00394">
        <property type="entry name" value="NAD_Glyc3P_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00957">
        <property type="entry name" value="NAD_G3PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword id="KW-1208">Phospholipid metabolism</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000072229" description="Glycerol-3-phosphate dehydrogenase [NAD(P)+]">
        <location>
            <begin position="1"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="255"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
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        <property type="protein sequence ID" value="BAF86282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_0284"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
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            <dbReference type="EMBL" id="BAF86282.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0286"/>
    <dbReference type="EnsemblBacteria" id="BAF86284">
        <property type="protein sequence ID" value="BAF86284"/>
        <property type="gene ID" value="AZC_0286"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0286"/>
    <dbReference type="eggNOG" id="COG1643">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001832_5_6_5"/>
    <dbReference type="OMA" id="DLRILVM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010225">
        <property type="entry name" value="HrpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013689">
        <property type="entry name" value="RNA_helicase_ATP-dep_HrpB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08482">
        <property type="entry name" value="HrpB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005496">
        <property type="entry name" value="ATP_hel_hrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01970">
        <property type="entry name" value="DEAH_box_HrpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="43"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="233"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="828"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="852" mass="91085" checksum="F75447C5C889589C" modified="2007-12-04" version="1">MPQAGTPGWISGPPMAYVQASMTAQGSMFDTRLPIDDALPALTATLRDHVAAVLVAPPGAGKTTRVPLALLDEPWVKGGKILVLEPRRLAARAAAHRMAQTLKEKVGETVGYRVRLRSEVSRRTRIEVITEGVFTRMVLDDPELSGIAAVLFDEYHERSLDADLGLALALETQRGLRDDLRLLAMSATLDGARVAALLGDGAPAPVVESEGRAYPVDTRYLGRDPRAPIERQVVDAVLKALSAERGSVLAFLPGAAEIRRTQTHLLADVRDRDTDIVALFGALDAAEQDRAVLPAPPGKRKVVLATSIAETSLTIEGVRVVVDCGLARVPRFEPDVGLTRLETVRVSRAAADQRRGRAGRTEPGVCYRLWGEGETQSLPAFATPEILAADLSGLVLDLASAGVRDPRALPFLDPPPLPAVTEAKNLLRVLDAIDADGAVTPLGARMARLPLPPRLAHMVVRGSDLGAGESAADIAALLTERGLGGDSPDLAHRLEDFRRERSRRAEDARRLAGRWAELARESHPPKAGETPSPAALLALAYPDRVAKARGDGTRILLANGRGAVVDPASSLARAPYLAVAEISGRADAARVQLAAAISGEEIERLFADAITAGLEVAFDPATASVRARETRRLGALTLADRPQPVPNTPETAAALAEGLADLGIERLPWTPALTQWRDRVRFLHQAEGAPWPDLSDAQLAATAAEWLAPFLTGRTSLGQVSAGDLGNALHALLPYELTHRLETEAPSHFTAPTGSNLPIDYAAEGGPLLPVRVQELFGLTRHPAIAGGKVPLTLALLSPAHRPIQVTKDLPQFWQGSWRDVRAEMRGRYPKHPWPEDPANAPPTNRAKPRGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJU3</accession>
    <name>A8IJU3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0359</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168890.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0359"/>
    <dbReference type="EnsemblBacteria" id="BAF86357">
        <property type="protein sequence ID" value="BAF86357"/>
        <property type="gene ID" value="AZC_0359"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0359"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_089963_0_0_5"/>
    <dbReference type="OMA" id="FFQENAS"/>
    <dbReference type="OrthoDB" id="1133475at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014605">
        <property type="entry name" value="Sig_resp-reg_PhyR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036400">
        <property type="entry name" value="RR_Ctr_UCP036400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="134"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="265" mass="28893" checksum="92EA2B2E473E5539" modified="2007-12-04" version="1">MPQQQLIKQLPLLRRYARALLGSQEAGDRLVRDTLQAVVDGQVSIDPNVSPRVALYRALHQIWEPRSTPDVAVGSHADQRLQSLNASSRVALLLTAMEGFSYAEASAILRVGLEDVEQQVVAAQAEIDRQLATRVLIIEDEWVIALDLKTLVTDLGHEVVGVAPTHTKALELAKDGDFGLVLADIQLADGSSGIDAVTDILGSFDVPVIFITAFPDRLLTGERPEPTYLITKPFLSETVKATIAQALFFHQTKSDAAQERAQRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK24</accession>
    <name>A8IK24_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0391</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168922.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0391"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86389">
        <property type="protein sequence ID" value="BAF86389"/>
        <property type="gene ID" value="AZC_0391"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0391"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_375841_0_0_5"/>
    <dbReference type="OrthoDB" id="865276at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018831">
        <property type="entry name" value="Uncharacterised_NKWYS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10364">
        <property type="entry name" value="NKWYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="290"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="738" mass="80864" checksum="28AC5154D9399E1B" modified="2007-12-04" version="1">MILTLTYAKVCTTSLHHLLTERFPGDVFRSHGLEPWILDPLERFAAAVTADTSGLRGSFDNGPIRERLAHARATGETITIISGVRDPVSRSLSVAMQNLEAAFADCVSPSVQASAEAIATRVADLWLRETTNGDPVRTFLEKMIRAPFEWFEQELAGPFGFDLREQAFDTVQGYSIQSRDNVRLLLFRHERAPAAIEKGLTELFPGMDFVLPHDNTGEDKPSGGIYRALRQCFRLPRATLEAIYAHPDVRPYFGEDEITAAIERWAEPAPQSAWVMPPPPAAPRQTFAATVFIPLRNHAQWVGAQIDSLLAQWRPDVELVLVDDGSQDGSLAAALDRLGGRPEVMATVMRNSTALGHGMLPAVLGLSRAPVIIQADSDDIALPGRLDTIIGHFAADPDCRLVTSNAVLLSETGISIGVLDPHAADARLDDPVALPDLQHNSYWLGASSAFHRSVIEAFPPLDPELCAYGLDLLTGFRAILLGSQHYLAQPLVGWRQHARNSHRVIGTFDATPASKEHLAAIAFMTRAQRLRDLAWLQAQSQIAPERAARIDARWRADHSAQADEWIRLRNRLTGTHAAPNPLDSRASEGAAHVPAVPPILTLTRGFEWSAAQLDPALSRWSGTYGGDSRMLWISRQTAITLRIPEPDAEALVLTLAGIPYVDRQSVFLSLDFAPPMEITLVAGESRRVTVPIVQRRDPAGGLMTLMIRAPEAVRPCNLDPANPDQRMLGVALFAMQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKR3</accession>
    <name>A8IKR3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Precorrin-6x reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">cobK</name>
        <name evidence="4" type="ordered locus">AZC_3941</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172461.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3941"/>
    <dbReference type="EnsemblBacteria" id="BAF89939">
        <property type="protein sequence ID" value="BAF89939"/>
        <property type="gene ID" value="AZC_3941"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3941"/>
    <dbReference type="eggNOG" id="COG2099">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_068627_1_0_5"/>
    <dbReference type="OMA" id="THPYAAQ"/>
    <dbReference type="OrthoDB" id="1726104at2"/>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016994">
        <property type="term" value="F:precorrin-6A reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003723">
        <property type="entry name" value="Precorrin-6x_reduct"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36925">
        <property type="entry name" value="PTHR36925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02571">
        <property type="entry name" value="CbiJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00715">
        <property type="entry name" value="precor6x_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51014">
        <property type="entry name" value="COBK_CBIJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="262" mass="27954" checksum="9338B21BE6862B68" modified="2007-12-04" version="1">MPRHILILGGTGEARRLAARLAGEENLHAIVSLAGRTENPAQMPVPVRVGGFGGIAGLRDYLAAEAISAVVDATHPYAAQMSRHAAAACAALGVPLLALRRQPWKPVDGDRWREVEGVAGALAALGETPRRVFLALGRNEVRAFEAAPRHSYLVRSVDAVEPPLAVPNANYVVARGPFTAEGDLDLLRDHGIEIIVAKNSGGPATYGKMEAARALGLEVILLRRPDVPDVPAVETVEEVAHWLERTNAPDTQSRTRAHRSAL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKV0</accession>
    <name>RIMM_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rimM</name>
        <name type="ordered locus">AZC_3953</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RimM family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172473.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IKV0"/>
    <dbReference type="SMR" id="A8IKV0"/>
    <dbReference type="STRING" id="438753.AZC_3953"/>
    <dbReference type="EnsemblBacteria" id="BAF89951">
        <property type="protein sequence ID" value="BAF89951"/>
        <property type="gene ID" value="AZC_3953"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3953"/>
    <dbReference type="eggNOG" id="COG0806">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077636_0_1_5"/>
    <dbReference type="OMA" id="DEFYHAD"/>
    <dbReference type="OrthoDB" id="1497415at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="chain" id="PRO_1000070957" description="Ribosome maturation factor RimM">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="PRC barrel" evidence="1">
        <location>
            <begin position="92"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <sequence length="177" mass="19032" checksum="3FA0D02FCBF9517B" modified="2007-12-04" version="1">MTDRILIARIGAPHGVKGEVRLFAFGEDPLALKRYPLTDESGARRFKVQSLRAAKDHFVARLEGIADRNAAEALTNTDLFVPRDALPAAEDEDTFYHADLMGLRVEDQSGALLGTVLAMHDFGAGDVLEYTPEGGGRTLLLPFTKAAVPVVDVPGGRIVVVPDTNPDETPPEDADQA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILC6</accession>
    <name>MDH_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Malate dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mdh</name>
        <name type="ordered locus">AZC_4016</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LDH/MDH superfamily. MDH type 3 family.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172536.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8ILC6"/>
    <dbReference type="SMR" id="A8ILC6"/>
    <dbReference type="STRING" id="438753.AZC_4016"/>
    <dbReference type="EnsemblBacteria" id="BAF90014">
        <property type="protein sequence ID" value="BAF90014"/>
        <property type="gene ID" value="AZC_4016"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4016"/>
    <dbReference type="eggNOG" id="COG0039">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045401_2_1_5"/>
    <dbReference type="OMA" id="MGWTSQA"/>
    <dbReference type="OrthoDB" id="870724at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01339">
        <property type="entry name" value="LDH-like_MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00487">
        <property type="entry name" value="Malate_dehydrog_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011275">
        <property type="entry name" value="Malate_DH_type3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01763">
        <property type="entry name" value="MalateDH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0560">Oxidoreductase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="chain" id="PRO_1000072417" description="Malate dehydrogenase">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00487"/>
        </source>
    </evidence>
    <sequence length="321" mass="33677" checksum="2032149C7B46F9AE" modified="2007-12-04" version="1">MARSKIALIGAGQIGGTLALLAGLKELGDVVLFDLVEGVPQGKALDLAELSPVAGFDAAFAGTGAYEQIAGADVVIVTAGVPRKPGMSRDDLLAVNLKVMEQAGAGIAKYAPDAFVICVTNPLDAMVWALQKASGLPRHKVVGMAGVLDSARLRYFLADEFNVSVEDVTAMVLGGHGDTMVPLMRYCTVAGIPVPDLIRIGWTSTDRIEAIVTRTRNGGAEIVELLKSGSAFYAPAASAIVMAESYLKDKKRVLPVAAPLSGEYGFRDLYVGVPAVIGARGVERIVELELDRAERAQFEQSVASVQGLVDACAKIAPDLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILI3</accession>
    <name>A8ILI3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Phosphate-binding protein PstS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_4037</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Part of the ABC transporter complex PstSACB involved in phosphate import.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 6">The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the PstS family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4037"/>
    <dbReference type="EnsemblBacteria" id="BAF90035">
        <property type="protein sequence ID" value="BAF90035"/>
        <property type="gene ID" value="AZC_4037"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4037"/>
    <dbReference type="eggNOG" id="COG0226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034528_1_0_5"/>
    <dbReference type="OMA" id="FPYPVYA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005673">
        <property type="entry name" value="ABC_phos-bd_PstS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002756">
        <property type="entry name" value="PstS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00975">
        <property type="entry name" value="3a0107s03"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PBP_domain" evidence="7">
        <location>
            <begin position="44"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="371" mass="38889" checksum="9881886B91F39CF7" modified="2007-12-04" version="1">MGGPKLRQDGNVPWQHLIGNGENPVKLTHILGAALAVAGTLVAGNASALDFNGAGASFPAPVYQSWGAKYKEKTGNGLNYQSIGSGGGQNQIINRTVDFGASDAPVEGPKLASNNLLQFPAVIGSIVATVNLDGIQTEQLKLTGPVLADIYLGKITKWNDKAIADLNAGVKLPDQAIVPVYRSDASGTSYVFTSYLAEVSADWKAKVGAATSVQWPTGAGAKGNEGVAGTVKNTKGAIGYVEFVYAAANKLVVTQLQNKAGKFVAPTVPAFMEAAAAADWAGSKDFAASMLNTPGANAWPIVSATYILLPKNPTNVDASKEVMKFFQWAYTKEGGEIAEKLHYIPLPEAVVKRVEEAWKAEVKAPDGKPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM65</accession>
    <name>A8IM65_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0497</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169028.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0497"/>
    <dbReference type="EnsemblBacteria" id="BAF86495">
        <property type="protein sequence ID" value="BAF86495"/>
        <property type="gene ID" value="AZC_0497"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0497"/>
    <dbReference type="eggNOG" id="COG1511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034730_0_0_5"/>
    <dbReference type="OMA" id="GHGQNRF"/>
    <dbReference type="OrthoDB" id="1344010at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="360" mass="38575" checksum="B107A9A5F469D1C5" modified="2007-12-04" version="1">MTRAVDPFLKVSSPRIFLVRIIVFLLLCAALAAVLYKQIAAAFMNNPGLNGVIFGVLAIGIILAIRQVSRLFPEVEWVNSFRLADPGLAVSRAPTLLAPMAALLGDRMGRMAISQSTMRSILDSIGTRLDEARDTARYLTGLLVFLGLLGTFWGLLETVSSIGGVIGSLQGGGDSASMLEEMKSGLSAPLAGMGISFSSSLFGLAGSLVLGFLDLQAGQAQNRFYTDLEDWLSTTVRDLDAEVPSRAPEVRPVPMDREAIDTRPVAQLLPPPAPIDLDPLVEAMGRLERTMTEAGSQRVTTAVAHLAESLQGLVTHMRTEQAVLKQLVESQGAQQADIRRVIERLERALNVPEDAGSGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMR4</accession>
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        <recommendedName>
            <fullName evidence="8">Carbamoyltransferase HypF</fullName>
            <ecNumber evidence="8">6.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hypF</name>
        <name evidence="12" type="ordered locus">AZC_0597</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + C-terminal L-cysteinyl-[HypE protein] + carbamoyl phosphate + H2O = AMP + C-terminal S-carboxamide-L-cysteinyl-[HypE protein] + diphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:55636"/>
            <dbReference type="Rhea" id="RHEA-COMP:14247"/>
            <dbReference type="Rhea" id="RHEA-COMP:14392"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:76913"/>
            <dbReference type="ChEBI" id="CHEBI:139126"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; [NiFe] hydrogenase maturation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the carbamoyltransferase HypF family.</text>
    </comment>
    <dbReference type="EC" id="6.2.-.-" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169128.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0597"/>
    <dbReference type="EnsemblBacteria" id="BAF86595">
        <property type="protein sequence ID" value="BAF86595"/>
        <property type="gene ID" value="AZC_0597"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0597"/>
    <dbReference type="eggNOG" id="COG0068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009164_0_0_5"/>
    <dbReference type="OMA" id="VQHHYAH"/>
    <dbReference type="OrthoDB" id="48295at2"/>
    <dbReference type="UniPathway" id="UPA00335"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046944">
        <property type="term" value="P:protein carbamoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004421">
        <property type="entry name" value="Carbamoyltransferase_HypF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041440">
        <property type="entry name" value="HypF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011125">
        <property type="entry name" value="Znf_HypF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17788">
        <property type="entry name" value="HypF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07503">
        <property type="entry name" value="zf-HYPF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006256">
        <property type="entry name" value="CMPcnvr_hdrg_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00143">
        <property type="entry name" value="hypF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="10">
        <location>
            <begin position="7"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="YrdC-like" evidence="11">
        <location>
            <begin position="197"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF86595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="763" mass="79682" checksum="4C6C1FCF596DA996" modified="2007-12-04" version="1">MERTGEAEEITVRGIVQGVGFRPFVWRLARRFGLAGSVSNTGDAVRIHIRGPVEARAAFVAALVAEAPPLARVEQVTRVPAAPVEGAEFHIAESGLGTVSVGIVPDLATCPACRSEIADPKARRFRYAFTNCTDCGPRFSIVEGLPYDRPRTTMRAFALCPDCRREYDDPADRRFHAQPIACPTCGPRLRFGAFEGDAALAAAASALKAGAILAVKGIGGFHIACDATSEAVVAELRRRKQRPAKPLAVMVADLAAARALAEVSALEAEALSDPSAPIVLLRRHLDGPLAPSVAPGQSHVGLMLTYTPLHHLLLASVGGPLVMTSANRANAPQVFRDEEAEAALAGIVDGLLTHDRPIARRLEDGVVRIAAGGVRVMRRGRGQAPRALDWPADFEGAPPILALGSDLKSAACLSHGRKALLTHHLGDLDTPAVEDEFARALADMADVFAHHPEAVAVDLHPGYRATQFGTALAVERGLPLLAIPHHHAHIAATLAENGWPRLGGPVVGLALDGLGLGDDGTLWGAEVLVCDYRESRRIARLVPIPLAGGDVASREPWRVLLAHLDTAVGEDGFPADLLDGKPLATVRAMIAKGLNAPLASSAGRLFDAMAALLGLAPDRLSFEGEAAMALEACAGDIMAAPYPMAVREADGLMELDPAPLWRTALADRAAGVPAPAMAARFHAGVAAAFADLAAWVAEGHGLSTVALSGGVFQNARLLEDVAARLSAHGLAVLLPAEVPANDGGLAFGQAAIAAARLMASEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMY2</accession>
    <name>A8IMY2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative chromate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3677</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172200.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3677"/>
    <dbReference type="EnsemblBacteria" id="BAF89675">
        <property type="protein sequence ID" value="BAF89675"/>
        <property type="gene ID" value="AZC_3677"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3677"/>
    <dbReference type="eggNOG" id="COG2059">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018106_0_0_5"/>
    <dbReference type="OMA" id="YQGAVGH"/>
    <dbReference type="OrthoDB" id="1884249at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="462" mass="48102" checksum="53242C4523993ACE" modified="2007-12-04" version="1">MPSAGGTTTSTAPAPAAPVALPSFGEAVRVWARIGLLSFGGPAGQIATMHRELVEERGWISETRFLHALNYCMLLPGPEAQQLATYVGWLLHRTLGGLVAGLLFILPGAVVMSALGLLYAVSHDVPLISALFFGIKAAVLAVVVQALLRIGRRALSTRLHLAIAALAFVAIYAAQVPFPLVVLAAGLFGFAFAGKGFGAPAAPAAGEGIVDDLFAQGAMAHTHPSAGRALKVLAVWLPAWLGPVALLALLTGPHSVWATIGSFFSVMAVVTFGGAYAALAYVAQAAVETFGWLSPHEMVDGLGLAETTPGPLILVLQFVGILAAYRDPGALPAWLAGLFGGALTVWVTFAPCFLWIFLGAPYMEALRGNRRLAAAMSAITAAVVGVILNLAVWFALHVVFREVREWRVLGLSPDVPVLASVDWRAAVLAVGALVAMLRFRAGMMATLGVCALAGLALSWLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8INI1</accession>
    <name>A8INI1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent siderophore receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_3754</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3754"/>
    <dbReference type="EnsemblBacteria" id="BAF89752">
        <property type="protein sequence ID" value="BAF89752"/>
        <property type="gene ID" value="AZC_3754"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3754"/>
    <dbReference type="eggNOG" id="COG4774">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008287_9_1_5"/>
    <dbReference type="OMA" id="TWGSDQT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015344">
        <property type="term" value="F:siderophore uptake transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030148">
        <property type="entry name" value="Fiu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010105">
        <property type="entry name" value="TonB_sidphr_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552:SF68">
        <property type="entry name" value="PTHR32552:SF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01783">
        <property type="entry name" value="TonB-siderophor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="127"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="332"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF89752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="831" mass="90184" checksum="798CA6737433ABBF" modified="2007-12-04" version="1">MSQMWRFGVIFRCGRASVGNMEEKYRLDIACPRAVLRAFLEMIDMPANVAGEGIRTSSQPEGVRAALMGSLHLTVGMASVMVAGPALAQQAAAPSTEVDLPTVQVQGDGTSFSSNSTGVTRLPVPIFDMPQTVNVITEEVMREQNTVTLEQALRNVSGITFSAGEGGQQGDNPIIRGFSARGDIYRDGIRDPGWYTRDMFDIEQVDVFLGPSSFAFGRGSTGGAINMVSKLPKNATFVNADVSAYTSQGWRTTLDANGKYNDNIYARINLMAQDIDTADRDNVNATRWGVAPSITAKLNDKTTATLSYYYQHEESVPDYGVPYYPAPVVSTALGTFGQPQGGYFGNGAATPPVNVPRNTWYGVTNGPYKDQVTTDTNMVTLQLQYELNDYVTLTNGTRYTANDRLARVTAPRALGTSGNVSFASPLPASQYYYPTSAMTIGMQRFQTETDNTQFTNITDMVAKFKWGQFEHTLNAGIEVTSEGRYQQRYNLCNQTVVACRVSLINPLDVSANFGLGGYTNYLPTSTVTTDMTDVGFYAADQIKINQYWQIMGGFRLDAASTNYNSFAITTSGSSITGTQTTLQNSETMFNYKVGTIFTPIEPLNLYVTYGTSSNPSSEYGVLDSGTATLAPESNTTAEAGFKAMLLNNQLTVTGAIFQTMKTNTRVATDTAAGLPPTVLGGEQRVQGYTLGATGNLTKDWNITASFTHLDSEIMSVGPAPTVANLQTLGKQLPNTPPNSFSFWTSYNVTKELLVGFGGTYNDNTFANATNTVYVPSYWAFDAMASYQISKNFQVQLNVYNLTDELYYAQYYGGQAVPAAGRTGTLTARATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8INK9</accession>
    <name>A8INK9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_3763</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.</text>
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            <begin position="293"/>
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    </feature>
    <feature type="domain" description="FtsX" evidence="8">
        <location>
            <begin position="754"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8INL8</accession>
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        <submittedName>
            <fullName evidence="3">Putative two-component sensor histidine kinase</fullName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172289.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3766"/>
    <dbReference type="EnsemblBacteria" id="BAF89764">
        <property type="protein sequence ID" value="BAF89764"/>
        <property type="gene ID" value="AZC_3766"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3766"/>
    <dbReference type="eggNOG" id="COG5000">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_1003428_0_0_5"/>
    <dbReference type="OMA" id="VEHYETI"/>
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        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
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    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <location>
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    </feature>
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        <location>
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        <location>
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            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="172" mass="19241" checksum="683571CD9E0693AA" modified="2007-12-04" version="1">MGQVLHRCATTTDAVRRAIQHSQESLRARAKRDGINQKTAPRWKQRNSVADLPTGPKAPKSTVLSVEEEAIIVAFRHHTLLPRDDCLYALQATIPHLTRTSLNCCLQRQGISRLPEIAGDKETKKRFKSYPIGVFHIDIAEVQTAEGELYLFVAVDGSSKLPPCNWWTARTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPV2</accession>
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            <fullName evidence="1">Pyrimidine 5-nucleotidase</fullName>
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        <name evidence="1" type="ordered locus">AZC_0700</name>
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    <organism evidence="1 2">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0724"/>
    <dbReference type="EnsemblBacteria" id="BAF86722">
        <property type="protein sequence ID" value="BAF86722"/>
        <property type="gene ID" value="AZC_0724"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0724"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2972">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_27_5"/>
    <dbReference type="OMA" id="WNDEPSA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004090">
        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="347"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="7">
        <location>
            <begin position="434"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="593"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="697" mass="72780" checksum="E5EA62524AE13956" modified="2007-12-04" version="1">MRLSIKLTLLALFGLVSLIMAALCGSSLLTAYKRDLAAAEAQAYAEIDRGLFQAFTTLRTERSDSAAALSRPLDAMPPLVAGIAKRREKVDAGFAVALTELSSQGTPEAKDLAGRVEGIRKAIKDLRADIDRALQLPPDSRDKTLSTRIYDVTVRELDRLDDVSQDIGKRIRSLDISLTPYLSVRGTTGIVRNSEGNTVLAVSNALRKGEPLAPKDLTEVQAEEVRGQLGWSMVKEEVDNKDIPASLREAVAKADSAFFSGSFKTLKEDTLKTLSNGGKPPLTLDQWRSAAVPALETIGAVAITAMDEMADAAGAAAGRARASLALYAGLLVVALLIAGAGLVVVIRRVTRPISGLTATMQRLADGDLAVDVAGTRRHDEVGSMAKAVLVFKEEMARNTALEAEAKAAHVQAEAERREGMLKLAAEFESAVGGIIGSVASASTQLHGTARTMAEAARRTSEKSTAVAAAAEEASTNVVMVASSAEELGSSVDEIGRQVQQSAEMSSVAVAEAQKTGTVIQDLAQAASRIGDVVGLISSIAEQTNLLALNATIEAARAGDAGKGFAVVASEVKALATQTAKATEEIESQIGAIQATTKQAVQVIEGVGSQIRKMSDVATSISAAVEEQGVATREIVRNVDQAATGTNSVTAHISEVAQTADETGSAAGQVLTAAAALTDQAKRLEAEMQRFLGTVRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQJ3</accession>
    <name>A8IQJ3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Xanthine/uracil permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169321.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0790"/>
    <dbReference type="EnsemblBacteria" id="BAF86788">
        <property type="protein sequence ID" value="BAF86788"/>
        <property type="gene ID" value="AZC_0790"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0790"/>
    <dbReference type="eggNOG" id="COG2233">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017959_8_2_5"/>
    <dbReference type="OMA" id="WANEMPL"/>
    <dbReference type="OrthoDB" id="1419334at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017588">
        <property type="entry name" value="UacT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006042">
        <property type="entry name" value="Xan_ur_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00801">
        <property type="entry name" value="ncs2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03173">
        <property type="entry name" value="pbuX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="461" mass="47723" checksum="03CC1F2405774D44" modified="2007-12-04" version="1">MAVDAVDEFLPAPKMAALGLQHVLVMYAGAVAVPLIIGRALKLSPEDVAFLISADLFTCGLVTLVQCIGFPGVGIRLPVMMGVTFASVGPMMTMAATADIGLLGIYGAVIASGIFAILIAPFISRMLPLFPPVVTGTIILVIGISLMRVGINWAGGGLPMLTKVVNGEVVTVANPNYGQLPGLGLSLFVLLVILALIRWGKGFVANVAVLLGIVAGAVLASFTGVMHFEKVAAAPWFGLVLPLHFGLPHFSLVPIATMCIVMVVVMIESLGMFLALGEMTGRTVDQKALARGLRADGVGTLLGGLFNTFPYTSFSQNVGLVGVTGVKSRWVTATGGLIMLALGLLPKMAALVEAVPQVVLGGAGLVMFGMVAATGARILTAVDFKTNRFNLFIVAISVGFGMIPLVAPNFFKALPHELHPLLESGILLAAISAVALNVFFNGMKGASLDEVVAAAKQADAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQL6</accession>
    <name>A8IQL6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ordered locus">AZC_0797</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169328.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0797"/>
    <dbReference type="EnsemblBacteria" id="BAF86795">
        <property type="protein sequence ID" value="BAF86795"/>
        <property type="gene ID" value="AZC_0797"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0797"/>
    <dbReference type="eggNOG" id="COG0223">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033347_1_2_5"/>
    <dbReference type="OMA" id="CCPVVAY"/>
    <dbReference type="OrthoDB" id="2009156at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="204"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="307" mass="32348" checksum="9F86D59D3ADDA097" modified="2007-12-04" version="1">MRIVFMGTPDFSVPTLSEIVGRGHEVVGVYTRAPAPSGRRGLELVPSPVHTVAERFGIPVFTPKSLKGEEAAAQFRELGADVAVVVAYGLILPTSILDIPALGCLNLHASLLPRWRGAAPIQRAIMAGDKETGIAVMKMEAGLDTGPVGLLERVIIGPDMTAGELHDRLSYIGADLMGRALSALERGGLDFTPQPDEGIVYASKIEKAEARIDWSRPAAEVHNTIRGLSPFPGAWFPFGADEARVKVLRASLADGTGAPGTALDDQLTIACGTGAVRLTELQKAGKQPMSAATFLNGNDVPKGTRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQG0</accession>
    <name>A8HQG0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ferredoxin III</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fdxB</name>
        <name evidence="13" type="ordered locus">AZC_1034</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <authorList>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <property type="protein sequence ID" value="BAF87208.1"/>
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    </evidence>
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        <source>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki T."/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="BAF90183">
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        <property type="gene ID" value="AZC_4185"/>
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            <begin position="173"/>
            <end position="245"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="291"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF90183.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="325" mass="35318" checksum="660F784E04B26133" modified="2007-12-04" version="1">MRRLTVEHKTLYRYAEPVSFGTHRLMLRPRDSHGLRLLDARMTLSPPAEVKYVYDVFGNSIGLADFQEPGAELRIESTLELEIYPVPALQDLIAREAASYPFVYSSDDRLDIALPAARHYPDDGAVEAFARSFLPESGTRDTLDLLMAINGAIKERFAYQARYEEGTQAPADTLRLGSGTCRDFALLFMETVRELGFAARFVTGYLYTPQLDPLAGDAFQGAGATHAWAEVYLPGAGWIDFDPTNALVGTDHLVRVAVVRDPRQAIPISGSFSGTEGAFLGLEVDVRAACHSTDTEPAEAEAAAATDPLPAPSNDAAPEAPRPAA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0874"/>
    <dbReference type="EnsemblBacteria" id="BAF86872">
        <property type="protein sequence ID" value="BAF86872"/>
        <property type="gene ID" value="AZC_0874"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0874"/>
    <dbReference type="eggNOG" id="ENOG502Z82C">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044365_1_0_5"/>
    <dbReference type="OMA" id="GYRLANW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
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    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
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    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="PTHR33146"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
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            <begin position="1"/>
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        <location>
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        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="282" mass="30294" checksum="0B43329616172FBD" modified="2007-12-04" version="1">MSMAYLVRAFALALSFLAAPSTVWAWGEDGHAIVAEIAQRRLTPTGAALVASLLPKGASLASVASWADDVRPDHPETRRWHYVGIPMGAATYDPLRDCPSRPEGDCIVAAIERARLDMHCAPEPAARTDALKLLVHLMGDLHQPMHAIAADHLGTRRKVLLNWAGQACTHDCEAPPPTTNMHVLWDTTLVRKASLSWGGYVDRLEAGWLKEADAAAVAAGTPADWASETHGVGLAMYALVPPDNVINTTYYRAALPVLDQQLGKAGLRLAHEINAAVTCPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
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        <alternativeName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
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    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the phytochrome family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169446.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0915"/>
    <dbReference type="EnsemblBacteria" id="BAF86913">
        <property type="protein sequence ID" value="BAF86913"/>
        <property type="gene ID" value="AZC_0915"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0915"/>
    <dbReference type="eggNOG" id="COG0784">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4251">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_50_1_5"/>
    <dbReference type="OMA" id="GQYFPAS"/>
    <dbReference type="OrthoDB" id="1635706at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004673">
        <property type="term" value="F:protein histidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009219">
        <property type="entry name" value="Bactrphtchr_CheY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013654">
        <property type="entry name" value="PAS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001294">
        <property type="entry name" value="Phytochrome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013515">
        <property type="entry name" value="Phytochrome_cen-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043150">
        <property type="entry name" value="Phytochrome_PHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011102">
        <property type="entry name" value="Sig_transdc_His_kinase_HWE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07536">
        <property type="entry name" value="HWE_HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08446">
        <property type="entry name" value="PAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00360">
        <property type="entry name" value="PHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036397">
        <property type="entry name" value="Bactrphtchrm_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01033">
        <property type="entry name" value="PHYTOCHROME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00911">
        <property type="entry name" value="HWE_HK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="2" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="PHYTOCHROME_2" evidence="9">
        <location>
            <begin position="154"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="10">
        <location>
            <begin position="734"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="8">
        <location>
            <position position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="850" mass="91793" checksum="11406082354A9668" modified="2007-12-04" version="1">MPNAEAVDLTNCDREPIHIPGSIQPHGCLIACTPDAGHILCHSANAADVLHLPSAGINGLRLEAVLGGKAAHDIRNALTTATDPARPGLLLGLNIGERAFDVAVHIYKGVVIIECEAAPKGRSGTPVEFVRALISQVSRLGEPDVLLRRASHLVRTLLGYDRVMIYRFDADGSGKVVSEARMPSLESFLGQHFPAGDIPRQARELYLKNIIRIVSDSSGARIPMEPEFNASGEPLDLSFAHLRSVSPIHCEYLRNMGVSASMSLSIVIGGQLWGLIACHHYSPRVLSMAERIGAEMFAEFFSLHLEAVNHREKLEVATRARRTLDRILGHAARYAGLPELLRGSLADFMGLMPCDGVGLWIEGEWTSHGVALPAPAAPALARAVATHGEGPVWASHTLSHILPEVSAYGVPVAGALAISLSHRPRDYLFFFRKEAVQTVEWAGNPHKHYATGLHGDRLTPRKSFAIWKETVEHQSWPWTQADRDFAEAARNALVEIVLRHNELLADERGKADVRQRLLNEELNHRVKNILALIKSLVSHPVTEATDVASYSRSLKGRIEALAYAHDQVVRGDGGGLLSDLLTAELSPYRDATAVTLDGRPLMLDAQAFSVMALVFHEMATNAAKYGSLSTPGGRLMVRWVPAPAGGCDITWEESGGPPVQAAGRRGFGSVLVDRSVPYDLGGFSAIEYLVSGVKARFSIPGRHITWQGSDPRTVAPASASDAPPPDDLPLRGLSLLVVEDQLLIAMEAEAMLLALGAEAVETCNSALEAENRLARFRPDAAVLDIHLSGGTSVPVAQELRRRQIPFVFASGYADLDNIPDELADVPLARKPYDGKALAFALTQARAEAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU79</accession>
    <name>A8HU79_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dienelactone hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0916"/>
    <dbReference type="EnsemblBacteria" id="BAF86914">
        <property type="protein sequence ID" value="BAF86914"/>
        <property type="gene ID" value="AZC_0916"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0916"/>
    <dbReference type="eggNOG" id="COG0412">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_054590_7_0_5"/>
    <dbReference type="OMA" id="HIKAYVV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="78"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="302" mass="32587" checksum="33049DA0170CCA30" modified="2007-12-04" version="1">MEVRMTSPIAAPRAPAPELQGLDGLVREPFSRRGFVMTTVITGFTLATTTVLAQAIHTDATGLVAGEVQIPTSDGNMPGYRAMPEGNGPFPLVIVIEEIFGVHEYIKDTCRRLAKLGYCAVAPELYARQGDLTKMTDVQQIVSQVISKKPDAEMLSDLDAAVAWAVKDSKADGNRLAVTGFCRGGRATWLYAAHNPKVKAAVAWYGPLGGQRTDIQPKTAAEVVGDLKAPVLGLYGGADTGIPVADVEKQRDAAKAAGKTVEIVIYPDTPHAFHADYRPSYRKEAAEDGWKRMLAWFKQYGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="42" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVV3</accession>
    <name>A8HVV3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_4362</name>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        </source>
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            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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            <end position="26"/>
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    <feature type="transmembrane region" description="Helical" evidence="14">
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    <feature type="transmembrane region" description="Helical" evidence="14">
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            <end position="152"/>
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        <source>
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    </evidence>
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    </evidence>
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            <dbReference type="EMBL" id="BAF87426.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="259" mass="28693" checksum="A8ECA1F38812BA8F" modified="2007-12-04" version="1">MSALNSALFGWYPYLCLTVFLFGSLIRFDREQYTWKTGSSQLLRRRQLRLGSNLFHIGILAIFAGHTVGLLTPIWVFDAMGVSHSFKQGLAITAGGIAGVLCFIGISLLAHRRLFDPRIRATSSFGDTAILLILWVQLTLGLFTIFVSLGHMDGHEMVKFMNWAQGILTLQPQAAAYVADVNPIFKAHMLLGLTIFLIFPFTRLVHVWSAPVWYLGRPGYQVVRTRFAHGSGQPRRTASAPVVAPAPRATSIPAQRPAE</sequence>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF87470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1472"/>
    <dbReference type="CAZy" id="GT2">
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    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87470">
        <property type="protein sequence ID" value="BAF87470"/>
        <property type="gene ID" value="AZC_1472"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1472"/>
    <dbReference type="eggNOG" id="COG0463">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_033536_0_1_5"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="14"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="341" mass="37419" checksum="C513508B2E976B02" modified="2007-12-04" version="1">MRPPPVIRMTPDLSIVVPCYNEATGLPFFHERLSAHARKVAEARGMRIEIVYVDDGSRDQTAAVALALKPQGTDVQVVALSRNFGKEAALMAGLDHARGDALLFMDGDGQHPPEMIETFVGLWKDEGYDVAYAIKADRMDEPAARRTFVKIFYWLLNFGAQSRIPEDAADFRLLSPRAAAALRRLPERNRFFKGLSSWIGFRQKAVPYRPAAREHGTSSWSFLRLLGLSMEGLTSFSPAPLRLAGMVGAALAAAAFLYGSWIVIERLVWGIPLPGYPSLVVGLMVIGGVQLLVIGIMGEYIARILSEIKARPVYFVADHAVRHAEAAGDRPVGLELPKALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXS8</accession>
    <name>A8HXS8_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">ArgK protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">argK</name>
        <name evidence="3" type="ordered locus">AZC_1535</name>
    </gene>
    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1535"/>
    <dbReference type="EnsemblBacteria" id="BAF87533">
        <property type="protein sequence ID" value="BAF87533"/>
        <property type="gene ID" value="AZC_1535"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1535"/>
    <dbReference type="eggNOG" id="COG1703">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043725_2_2_5"/>
    <dbReference type="OMA" id="WMWERID"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408">
        <property type="entry name" value="PTHR23408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="363" mass="37874" checksum="73EED3A695557619" modified="2007-12-04" version="1">MIEARREPREASPPAPCAQGLMPPMDASPPLASPPAPAPDAADAMLAEQVARGERAALARAITLIESRRPDHRRRAEALLQTLLPRTGNAVRVGITGVPGVGKSTTIDALGSHLTAAGHKVAVLAVDPSSTRTGGSILGDKTRMARLGTDPNAFIRPSPSGGTLGGTAAKTRETMLLCEAAGFDVVLVETVGVGQSETAVADLTDTFLVLMLPGAGDELQGIKKGVLELADIVAVNKADGDNLPRARAAAGEYRAALHLLGARQPFWSPRVLTYSALTDDGVAQVWEAVLDHRKAAEAAGALAATRQAQQVRWMWTLLQERLAEKVRTDPAIKARLPGLERSVADGTLAPTLAANEIAALLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY49</accession>
    <name>A8HY49_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Secretion protein HlyD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hlyD</name>
        <name evidence="3" type="ordered locus">AZC_1576</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1576"/>
    <dbReference type="EnsemblBacteria" id="BAF87574">
        <property type="protein sequence ID" value="BAF87574"/>
        <property type="gene ID" value="AZC_1576"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1576"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_2_0_5"/>
    <dbReference type="OMA" id="KVYFTEG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="70"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="391" mass="41723" checksum="9A1E2FDF7EC442D8" modified="2007-12-04" version="1">MRWCMGGAKRTGRWRFYFLFFCLVAAGGAGWAWSQGLIGKGGGTAKAQSQPERRVAVVVATAQDRPMPVRIEALGTVEPQVTVTIRSRVASQVTSVAFEDGAVVNKGDLLFQLDPREVDAQILQARATLAKDKTQLEKALRDMERYSGLAARNTVSQVTLDDARTTADAQKATVDQDEANLKALEVQRTYYDIRSPASGRLGVAAVRPGAVIRVDDTLATVRQIKPIYVAFGVPEHYLRDIRAAQNDAKVEIALQGSKDVVGDGRISVIDNTVDPQTGTLMVRAVFENADERLWPGTLGAVSVTLRMESGVVSVPAEAVQSGQSGTFVFVVENDTAHVRPVTMARTVDGYAVITAGLKGGEVVVTDGQLSLREGSRVSVKGAAASTPAPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYB1</accession>
    <name>A8HYB1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1595</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    </reference>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="3">
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
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        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90485.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="85" mass="9466" checksum="03CF75B859F47BF2" modified="2007-12-04" version="1">MLCRRSTDTANRQCRLKGVRVHATRDARPRPSDSEDSPVPSLLRFLLVVAILAGLGYAGIWALATMVEPVQRETTFVVPNDRFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
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            <fullName evidence="2">DUF4167 domain-containing protein</fullName>
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        <name evidence="3" type="ordered locus">AZC_4494</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173013.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4494"/>
    <dbReference type="EnsemblBacteria" id="BAF90492">
        <property type="protein sequence ID" value="BAF90492"/>
        <property type="gene ID" value="AZC_4494"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4494"/>
    <dbReference type="eggNOG" id="COG5373">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_062575_0_0_5"/>
    <dbReference type="OMA" id="ENYFQHG"/>
    <dbReference type="OrthoDB" id="2001042at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025430">
        <property type="entry name" value="DUF4167"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13763">
        <property type="entry name" value="DUF4167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4167" evidence="2">
        <location>
            <begin position="7"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="375" mass="42892" checksum="1F78ADA4052CE5EB" modified="2007-12-04" version="1">MRNGQQKRMRGRNRRSSNPMTRVYESNGPDVKVRGTAHHIAEKYLQLARDAQSSGDHVAAENYYQHAEHYQRLIASLQGQFGQPGFGREDEMDDEDMDEAGFDGPQPGYQPREQNYQGRDREQNYQPRENRQPRDNRQNGNQPRRNRDEDGEGNYQPREFRSRRDDNEGGYQPRENRQPREPRQPREEGEGHYGRQPRMPREEGEGGYAPRPPRQPREEGEGYAPRPAREPREPREPREEGEAPYAARAPREERESAPAPRSRRSRDDSESYSAREPREPRPAPVSEEAAPAPAPAPTRSRARKEREPAQPELGLPSFITGGTKERAAAAPAPAASEEQGEEAPRFATRRRRRFRTTEEGAEAAPAGSTEPQFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8I031</accession>
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        <recommendedName>
            <fullName evidence="2 3">Diaminopimelate decarboxylase</fullName>
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            <shortName evidence="2">DAPDC</shortName>
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        </recommendedName>
    </protein>
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        <name evidence="2" type="primary">lysA</name>
        <name evidence="6" type="ordered locus">AZC_4659</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173178.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4659"/>
    <dbReference type="EnsemblBacteria" id="BAF90657">
        <property type="protein sequence ID" value="BAF90657"/>
        <property type="gene ID" value="AZC_4659"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87222.1"/>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="302" mass="31517" checksum="1B4FA2DBBBEF6E1A" modified="2007-12-04" version="1">MRAWDCDVQVTVLPQLTPNRAALQRRNATPPIRVSRSATGMTGKMGMTTATILRRASALAVAAMTLGVASGALAQNAAPAKPAPAKPAQGQQAPAQAQQQQAAGPQSVAVPGINTPWTKVCGTDQAANKQICMTTQDFTAETGQPLASAAIREMQDDPVKKFIVSVPIGMLIQPGTRVVIDKEAPLSLKYEICFPNGCFASMDVNAEFVTKLKKAQNITIQALQMGGRTLNFVLPAKDFAKAYDGAPSDPNVVAAERQKLAEELQKRAQKMMEERAAAQGGAPAQGAAAPAPAAAPAAPAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="96" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1G2</accession>
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    <organism evidence="7 8">
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
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                <person name="D'Haeze W."/>
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                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="6">
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <property type="entry name" value="fer2"/>
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        <property type="entry name" value="FAD_FR"/>
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    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="224"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
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        <source>
            <dbReference type="PROSITE" id="PS51085"/>
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        <source>
            <dbReference type="PROSITE" id="PS51384"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="311" mass="33464" checksum="B00C266328B5233A" modified="2007-12-04" version="1">MAETELLTPDIRRVRFVATSGAPLPLFSGGAHVVVSLPTPRGVLRNPYSLTSCPTDGSGYEICVQKSATSRGGSAFVHEGLAAGDELEISWPVNLFGMDRRARKHLFIAGGIGITPFLSMMQQLAMEGGTFELHYAMRSPDTGAAREMVAERYGAHRVRTYVSSHGTRIPLPDLLDGQPLGTHLYVCGPTRLIDDVLLQAREAGWPDENVHSERFAAPPPGKPFLLELARSGQRIEVGSHQSVLEAMEAAGLSAPNLCRGGACGQCETGVLACDGALEHHDHFLSPDERAGGRKFMICISRIAGERLVLDL</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF87391">
        <property type="protein sequence ID" value="BAF87391"/>
        <property type="gene ID" value="AZC_1393"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1393"/>
    <dbReference type="eggNOG" id="COG1529">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
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        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
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        <property type="entry name" value="OxRdtase_Mopterin-bd_su_IorB"/>
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        <property type="entry name" value="TAT_signal"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="211"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="722" mass="76556" checksum="FBF690001B187D19" modified="2007-12-04" version="1">MQPDSPTLSRRSLLRGAAAVLGGLVIGIELPARRARADEPQASGAAVNAFVHVPAQGPVSLIMPAVEMGQGVYTSQAMCMAEELEIGLDQVQAIAAPPDREHYGHPIFYVQATGGSTTTMAWTEPLRKAGATARAMLVAAAAEAWNVPASELTTEQGVITHRPSGRTVRYGEVADRAAALPPPANVSLKSPDQFRLIGTRAKRIDTPDKVTGKTVYGIDVMRPGMKFAALMASPVLGGKVEHVDQGPALKVAGVRQVVVLDDMVAVVGDNTWAAEQGLRALDIAWAAGPNATLNQAQLWADTEKASEGPGVTVRKEGDAAGKLKSGTVVEATYELPFLAHTSMETQNCTVHVHDGGCEIWVGTQVPGFAQAGAAQVLGIPPEKVTVHNHLIGGGFGGRLEAAPIVTATRIAQKVDGPVKVIWSREQDIRQDMFRPLYHNRLKARVENGRITAWQHRVTGPSILARWLPPAFKDGIDSDAIDGAAEPPYALGDMLVEYIRHENVVPFSFWRGVGPNSTVFSVESFLDRIARQSNTDPLTLRRGMLEKNPRGLAVLNAAVAKAGWDKPVAGSPFGSRTGRGLSLMHAFGSLLACVAEVTVTDHGDVRVTKVVVAADVGRVINPDTVIAQIQGGVVFGIAAVLHNRITFAGGEVEQSNFNDYRLLRINEMPTIEVELLSSQEASGGIGEPGTVIVQPAVANAVYAATGVQLTRMPLDASLLAKSV</sequence>
</entry>
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    <name>A8I2G2_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1869</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1869"/>
    <dbReference type="EnsemblBacteria" id="BAF87867">
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    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1869"/>
    <dbReference type="eggNOG" id="COG1173">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="113"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="157"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="89"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87867.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="292" mass="30978" checksum="112DFA09F0D94CD8" modified="2007-12-04" version="1">MSAIGSMQSHARRLRLGELLANPALLFGGTILLLVVLSAIFAPQIAGTDPFLIRPRLRFRAPDSAFWFGTDALGRDVFALVVHGGRLSLLVGLLCALAGAVIGSLLGLVAGYLRAFDAVIMRLMDGMMAIPSLLFAVALVCLVGPSLFSIVAAITFSEIPRVTRLVRSVVLSVREESYVRAAEGLGIPGYLVLLRHILPTCLAPLIVQTTYMFAAAMLAEAVLGFLGVGFPPDMPSWGNVLAEGRAVFQRAPWTIIAPGLFLAATVMAVNLLGDGLRDRLDPRLSRATGATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="51" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1890"/>
    <dbReference type="EnsemblBacteria" id="BAF87888">
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        <property type="gene ID" value="AZC_1890"/>
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    <dbReference type="KEGG" id="azc:AZC_1890"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="IVECGVF"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="SAM-dependent_MTases_sf"/>
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    <dbReference type="InterPro" id="IPR008884">
        <property type="entry name" value="TylF_MeTrfase"/>
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    <dbReference type="PANTHER" id="PTHR40036">
        <property type="entry name" value="PTHR40036"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TylF"/>
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    </dbReference>
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        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="268" mass="30751" checksum="32E18417D0051790" modified="2007-12-04" version="1">MKGRDGMADRDKAREEENLLGFTRAFNAAEHAARQDLEEAHRTSPIPRNERMDNLALFADHLLLGRILFMDHIYRLILNTPGVVMEFGTRWGQNLSIFSNLRTLYEPTHYHRKIIGFDTFSGFVDVAPQDGTSVYAQPGNVRTTQGYETFLERVLSAQEAFKPLPHKKKYEIVKGDVRETLPHYLDRHPQTIIALAYLDMDLYDPTREVLTKIRPYLVRGSVVVLDEINDPGFPGETVALREVFGLTGLRLQRVPYLSFPCYFVHDIA</sequence>
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        <name evidence="2" type="ordered locus">AZC_1902</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1902"/>
    <dbReference type="EnsemblBacteria" id="BAF87900">
        <property type="protein sequence ID" value="BAF87900"/>
        <property type="gene ID" value="AZC_1902"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1902"/>
    <dbReference type="eggNOG" id="ENOG5033ZWU">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_1493290_0_0_5"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="180" mass="18194" checksum="A13DFEFC1E7F7C35" modified="2007-12-04" version="1">MSVAKRCSAGDVGPEGQRSGKAAALAPFRRAPAARRTAPGGRMPDAPPPIITQEIRIVNPAGEPRLILSAAGGTPSVVLLGNDATPKARLALDADGRPSLVLSNPDGNGPVAAIEIDDKGAHVKFDRPGGASSYLFLNTGGGSGLVLIDSTGKRRVSVVVGPDGHVAVQGFEGSDPLPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2Q8</accession>
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        <submittedName>
            <fullName evidence="4">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1918</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF87916.1"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1918"/>
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        <property type="project" value="UniProtKB-KW"/>
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            <end position="186"/>
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    <feature type="domain" description="HTH_8" evidence="3">
        <location>
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            <end position="314"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
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        </source>
    </evidence>
    <sequence length="321" mass="34912" checksum="66A3CC6CC4973F7F" modified="2007-12-04" version="1">MNRVSSQHADRIETAIRSGGAVSSALVASWQRSVALYRLDPTERRSPQRLEQQKLSEARQRLEPMLRAAQASLDRLFLAVGGMGCCVLIADREGIPVERRGLAGDDDTFERWGLWPGCIWSEEHEGTNGIGTCLAEQRALTIHRDQHFFARNTLLSCTTVPIHDHEGHIAAALDVSSCRSGLTEELVNVIALATGDAARRIEAENFRQAFPNARIVVARMDDWSPHALLAVDGEDIIVGATRAARQAYRHLGAVIGKPLSLTDGAAGGQGFDAELRQAERAILERALIRAGGNVTAAARQLGLSRATLHRKLGKLGLERAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2S7</accession>
    <name>A8I2S7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_1928</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1928"/>
    <dbReference type="EnsemblBacteria" id="BAF87926">
        <property type="protein sequence ID" value="BAF87926"/>
        <property type="gene ID" value="AZC_1928"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1928"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_3_5"/>
    <dbReference type="OMA" id="HWTASQF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08415">
        <property type="entry name" value="PBP2_LysR_opines_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037424">
        <property type="entry name" value="NocR_PBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="314" mass="34094" checksum="A1565AEEE8E9066B" modified="2007-12-04" version="1">MIGIPYGSDMARRRMGLQHIEAFRAVIQTGSMTEAARRMHTSQPQISRLVAQLEQIAQFALFDRSGSRVFPTAEGTRFFQEVEKAFTGLTTLEAAAQGIRSFRADRLRVTAMPRLASGLLTRIAANFMMDYPEAMVSIRSGTATTVHEWVSSGLCDVGLAMLYQETSGVEVEPLFTGQCVAVLPTGHPLAARDVLTPADLAEQPFIASPSGGQLAERIDQVFNAANARRRIVAETDLGASVCTLVGAGLGVSVINPLAAHEERENAGLLIRPFQPAIATTVALIYPPYVARSRLVSVFSDYARRRVQQELTLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2Y3</accession>
    <name>A8I2Y3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sensor protein QseC</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_1954</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1954"/>
    <dbReference type="EnsemblBacteria" id="BAF87952">
        <property type="protein sequence ID" value="BAF87952"/>
        <property type="gene ID" value="AZC_1954"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1954"/>
    <dbReference type="eggNOG" id="COG0642">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_37_5"/>
    <dbReference type="OMA" id="NHAMVIH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013727">
        <property type="entry name" value="2CSK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08521">
        <property type="entry name" value="2CSK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="226"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="436" mass="46133" checksum="45B7CB23E6F1DADF" modified="2007-12-04" version="1">MLALGALLLSFAAWEYAKVAARDAYDKLLIGGAVQIAENVYVQGGVVALDPPAAAFSTLSAYDLVFYRVTDPRGVVVAGYDDLAKGVGGAALHRGVVLRDGTYQGQPVRIAALGKQLEDAGGGWAEIVLAQTMRAREALAWDLTTKAVALIAVMSLLGLLATALSLGLAFSPLTRLEGEIAGRRPDDLRPIQVSPPREVRALVGAIDGFMRRLEERIVMMQRFIADAAHQIRTPLAAIDAEAELLSDELDDPARMDPLRNRIADVGRLASQLLDHAMVLHRMETARLQPVELNALAKSVLAQTVPLSLEREVSITFVPAPGEVTIAGDPISLREAIANLIHNAVVHGARARLAVEVGGDQAHAVVTVGDDGPGIPDGERERLCAPFQRGEGSHGSGLGLAIAAEVARAHGGGIRFEMREGLFCVSLVLAVAPAREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3C0</accession>
    <name>A8I3C0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">recO</name>
        <name evidence="9" type="ordered locus">AZC_2006</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecO family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170533.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2006"/>
    <dbReference type="EnsemblBacteria" id="BAF88004">
        <property type="protein sequence ID" value="BAF88004"/>
        <property type="gene ID" value="AZC_2006"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2006"/>
    <dbReference type="eggNOG" id="COG1381">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086029_0_0_5"/>
    <dbReference type="OMA" id="AYVSPKS"/>
    <dbReference type="OrthoDB" id="1758685at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="8">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="245" mass="26345" checksum="82DABFEDE1334F02" modified="2007-12-04" version="1">MEWTDAGIVLGVRRHGETSAIVDLMTRERGRHAGLVRGGGSRRLAALLQPGNTLHATWRARLEGQLGLMTVEPLTLRSDAIMRSAHGSFGVTHLVGLMRLLPERDPHPGLFASLDAILDAFDEPAHAGELLARFEMALLVELGFGLDLTTCAATGGNNDLAYVSPRSGRAVSRSAGEPYADKLFGLPTFLIGGIVPPSLPDMEEALRMTGFFLSTRVLEPRGLALGEARASFLAALRRALHQPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4P0</accession>
    <name>A8I4P0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="7">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_1754</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170282.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1754"/>
    <dbReference type="EnsemblBacteria" id="BAF87752">
        <property type="protein sequence ID" value="BAF87752"/>
        <property type="gene ID" value="AZC_1754"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1754"/>
    <dbReference type="eggNOG" id="COG0623">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_10_1_5"/>
    <dbReference type="OMA" id="GILDMIH"/>
    <dbReference type="OrthoDB" id="762291at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05372">
        <property type="entry name" value="ENR_SDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="26"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="198"/>
            <end position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF87752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="275" mass="29543" checksum="F7B7A00AE73CDDBE" modified="2007-12-04" version="1">MVTNDSASGLLKGKRGLIFGVANNRSIAYGIAKAARAQGAEIALTYQGEALKKRVEPLAAELGGHIVGHCDVTDPATIDAVFAETEKLFGSIDFLIHCIAFSDKDELDGRYVDTTADNFTKSMFISCYSFTALAQRAEKLMPNGGSLVTLTYYGAEKWMPHYNVMGVAKAALEASVRYLAADLGPKNIRVNAISAGPIKTLAASGIGDFRYILKWNELNSPLRRTVTTDEVGDAGVYLISDLSRGVTGEVQHVDAGYHIVGMKHPDAPDLALVRD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-06-10" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4R6</accession>
    <name>URED_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Urease accessory protein UreD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ureD</name>
        <name type="ordered locus">AZC_1763</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UreD family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I4R6"/>
    <dbReference type="SMR" id="A8I4R6"/>
    <dbReference type="STRING" id="438753.AZC_1763"/>
    <dbReference type="PRIDE" id="A8I4R6"/>
    <dbReference type="EnsemblBacteria" id="BAF87761">
        <property type="protein sequence ID" value="BAF87761"/>
        <property type="gene ID" value="AZC_1763"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1763"/>
    <dbReference type="eggNOG" id="COG0829">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_056339_2_0_5"/>
    <dbReference type="OMA" id="MARFCAQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01384">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002669">
        <property type="entry name" value="UreD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33643">
        <property type="entry name" value="PTHR33643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01774">
        <property type="entry name" value="UreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0996">Nickel insertion</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000340411" description="Urease accessory protein UreD">
        <location>
            <begin position="1"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01384"/>
        </source>
    </evidence>
    <sequence length="271" mass="28912" checksum="979B46049D1316A6" modified="2007-12-04" version="1">MAGAPRRQRAVGRVRLGVNAIAGKSRVSDVAEAGSLRVRMPRVDGPAVEGVLVNTAGGVACGDHFTIEVKAEAGAHAVVATPAAEKIYRSDGETARIDVAITVEAGAQVDWLPQETLLYDAARLARRFTVDLAPDATFLAFEAIAFGRVARGEEMRTGHLEDHWQVTRGGGLIYADAVRVSGPLGELLRRPTVAAGNRAWATLLYVAPDAEARLDEARALMESARSECGASAWNGLLAARWLAPDIETLRRDAVAFLNAFRGAPLPRVWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4U3</accession>
    <name>A8I4U3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative methylmalonyl-CoA mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1773</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    </evidence>
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    </evidence>
    <sequence length="610" mass="62826" checksum="C74773F7A7A72714" modified="2007-12-04" version="1">MTATLPFVTQAGPVTRADWLSLVEGVLKGAPYDKRLVTRTSEGLALDALPPRREEAVPIAGRAAGAPWTISARVDQPDLAAANAQILDDLENGASGLTLVYASSPSAHGFGLPDGAALETLLASVMPDLIETRLESGAFKGRENALAFADFIAARGLDPARVSVSFGLDPLADMAARGSAPMPWPGLAERVAESAAILKARGFTGPLLRADGAIHHAAGASDAQELAAVLAAAVAYLRALEKAGFSLEEAAGRIEVALTADVNQTATLAKVRAIRLLWGAVLREAGIGAGPLKVHATTAWRSLTRRDPYVNLLRATIAAFAAGVGGADGLTVLPFTQALGLPDAQARRLARNTQLILLEESQLHRVADPGAGAGAVEAHTDGLAAAAWDLFRAIEGKGGLAEALASGWWQGELAATRAKRAKDIATRREPLTGTSEFPILGQSVPEVLAPVPAREEAPNDLALAPQRLAEPFEALRDAAEATGTPQVFLATLGPIAAFTARATFAKALFEAGGLAVTVTDGYADFDALIAAFKASGTAIACIASSDEIYEAEAATIAAALKAAGARQVWLAGRGGDLEATWRAAGVDDFIFAGCDVLSVLKKAHGALGIG</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <location>
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    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="463" mass="51007" checksum="46AD69ADEF784045" modified="2007-12-04" version="1">MRRARRVSGGAPAQPALDAGPAHQRQQGRQLRPRLAPRQRQPQRMEQRPAAAPAGCLGRRDPALVGRSVPWLRRQHVCGHGEEGPVVVGDGRRHVGPADVPPAPRVGEAFKIAAHRQPEGFVGGKAQFRQTRLDRRERQEMERARGEARQIGRIEPRRCAGDAGEVHLGGERIKAFHRRDRFGRAHEHRQRRHRERLLARLAQRLQGQMPEALGQALAIRQRQEIVVGKARGRAAQRLEQLDLDGGVGDMILAANHVGDAHVEIVHHGGERVEEAAVGTHKNRIGEARRVHLLRAAHAIDPAHQPLVQPEAPVGTASFRLQPRPVGRAECQRRPVIDRRQATGPLQAALEVELFLCLVRGIKPPHALQPLDRRLVEPQAVGLPDRVVRRNAQPHEILSDSLREFGAGADRIGIVEAQHESAASPPGQQRVQQGGARIAHMDEAGGRGSETEYGGRRVGHGPTL</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2429"/>
    <dbReference type="EnsemblBacteria" id="BAF88427">
        <property type="protein sequence ID" value="BAF88427"/>
        <property type="gene ID" value="AZC_2429"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2429"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_2_0_5"/>
    <dbReference type="OMA" id="GQLMAIH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="92"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="389"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="441" mass="46595" checksum="9558703C7E38EA42" modified="2007-12-04" version="1">MNEPFRDPKGEPVQLDLPEVPARKKRRFPWSLLICAALVALVGAGWLIRPQQQAGPGMRRAFNGPVPVATATVEKGSLPVTLTALGTVTPLTTVTVRSQISGRLTKISFQEGQDVKAGDPLAEVDPRPYEAALKQAQGQLARDQAQLRNAQLDLTRYQTLVAKSAASQQSVDTQEALVAQYQGTVQMDQAQVRTAELNLEYCHIVAPVSGRLGIRQVDVGNYVQAGDSTGIVVITQLKPITVVFSLPEDVVPQVARRLEAKADLPVTVYDRNRRAKIATGQLITIDNQVDTTTGTVKLKAQFPNDDGSLFPNQFVNVDLLVNTMDGAVIVPSAAVQRGAPGPYVYVVGADQTVSVHKVKLGPSAGDKIAVLEGLNPGDKVVVDGADKLREGAQVTEPDAGQTPGQPGRRPGGPNAAAGQGPSGAPGAPGNGQPRRSQAPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6Y1</accession>
    <name>A8I6Y1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2057</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170584.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2057"/>
    <dbReference type="EnsemblBacteria" id="BAF88055">
        <property type="protein sequence ID" value="BAF88055"/>
        <property type="gene ID" value="AZC_2057"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2057"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_2_1_5"/>
    <dbReference type="OMA" id="VDRGMHE"/>
    <dbReference type="OrthoDB" id="916788at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="57"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="259" mass="27615" checksum="C3385B640AE05689" modified="2007-12-04" version="1">MTRRFAGWGRGLLTTVGLIGLWWLIAVAFALPPYILPTPPLVAQALWNGRFYLAGHAATTALEIGLGLFFGVLMGASVALAMAASPVVQRWLTPLIVVSQAIPVFALAPILVLWLGFGLASKVMMAVLIIFFPVAATFHDGLRRTEPGWLDLARTMRASRAAELRHIRLMAALPALGSGLRVAAAVAPIGAVIGEWVGAAGGLGYVMLNANARMQTALCFAALFILAVMAVALWQLVDVLLRRILYWVPDAAAARRGPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6Z8</accession>
    <name>A8I6Z8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-dependent synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88060.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2062"/>
    <dbReference type="EnsemblBacteria" id="BAF88060">
        <property type="protein sequence ID" value="BAF88060"/>
        <property type="gene ID" value="AZC_2062"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="482" mass="51159" checksum="19757653323B07F4" modified="2007-12-04" version="1">MTDPTCAGLFPEPDGTSDRPLVWDDRSGVWRTADDIRGLSLRLAQRIERPGKQLVFLLATNAPETLVGLLAAAAAGHAVALIDPTLSPDRLDDLVRDYRPELVIGTGAGALCQPGNWNVAPSDGVFPEIAARIGATGPSDIHPDLGLLLLTSGTTGSSKFVRLSWAAVTANARQIAASLAITRESVAIAHLPFHYSYGLSVITSHLAMGARIAFIDDALTSPSFWDKVADCGGSHFPGVPFHYRVLTRLGLDRAPSSVTCFTQAGGHLETLTQTTMIAVCEKRGARFYVMYGQTEASPRMSCVPSDRLLEKLGSVGLAMPEGRLSIIDGEGRPLPAGETGGVVYEGPNVMMGYATCRTDLSLGDTTGGRIETGDLGRLDAEGFLFLSGRAARFAKIAGLRLSLDDMERQLAGLGTVACLDLGERIAVVFEGDVPEGAKEQARTLALACKIPAATFQLRALPEIPRKTSGKMDYARAKEALNV</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <topology evidence="4">Multi-pass membrane protein</topology>
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    <comment type="similarity">
        <text evidence="4">Belongs to the SURF1 family.</text>
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        <property type="protein sequence ID" value="BAF88100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF88100">
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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            <fullName evidence="6">O-acetylhomoserine/O-acetylserine sulfhydrylase</fullName>
        </submittedName>
    </protein>
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        <name evidence="6" type="ordered locus">AZC_2180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG2873">
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
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        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
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        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
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        <property type="entry name" value="Cys_Met_Meta_PP"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CYS_MET_METAB_PP"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="427" mass="45245" checksum="85CCDEED7D624B3E" modified="2007-12-04" version="1">MSERTPGFSTLAIHAGAQPDPTTGARATPIYQTTSFVFDDVDHAAALFGLQTFGNIYTRIGNPTVAVLEERVAALEGGTAALAVASGHAAQHLVFHTLLTSGDEFVASRKLYGGSINQFNHAFKSYGWNVAWADPDNVSSFERAITPKTKAIFIESLANPGGIVTDIKAISAVAKKAGIPLIVDNTLATPYLWRPIEHGADIVIHSATKFLGGHGNSIGGVIVDAGTFDWTASGRYPFLTQPRPEYQGIVLHETFGNFAFAIAARVLGLRDLGPALSPFNAFLILTGIETLGLRVQRHSDNALAVANFLSTHPAVEGVSYAGLPGDRYHDLAKAYLPKGAGAVFTFRLKGGYQAGVNLVSNVELFSHLANIGDTRSLIIHPASTTHRQLSDEQKTLAGAGPEVVRLSVGIEDVADIIADLDQALAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
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    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2655"/>
    <dbReference type="EnsemblBacteria" id="BAF88653">
        <property type="protein sequence ID" value="BAF88653"/>
        <property type="gene ID" value="AZC_2655"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="91"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="544" mass="60036" checksum="D90F6EB781CB8AA3" modified="2007-12-04" version="1">MTSELDRLPFGPISRRLFLGGAGAAAATLFIGQNGKAFAAETGQKGGTLTMAVWPDPTALVCAFTSSDQVVLSSAKMTEGLVAYGYDFLPRPRLATAWEPSADGLSIKFTLRQGVKWHDGTDFTSADVAFSFLNLLKPNHPRGRGTFANLTAVDTPDAHTAILRFSKPSPVVMNALSGMESPILPKHIYENGDPLRNPANNAPIGTGPFKFVEWKRGSHIILERFDGYWAQERPYLDRIVMRIINDAGARAAALETGEILLAGPNPVPYSELARFRANPKFDVETRGEELLQHAQAIEVNLRNPILAKVEVRQAILQAVNREAMARAVWYQSGRPATSPIPYQAGDLRLANPPAYPFDVKKAEALLDAAGYPRGADKMRFKLRLDWLPLGEANLRAAEFIKQSLQRVGIDITIRSSDLPTYLKTIYGDYDYDLNVFLYAPIFDPSMGLQRFYWSKAAKPGSPFVIASGYSSPEMDKILESASTEMDPAKRKALFHDFQRLAMTDLPVLPLLDLDYTAIISKRVHGVMDMPEGIRGSFENVWLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8U3</accession>
    <name>A8I8U3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">(S)-2-haloacid dehalogenase</fullName>
            <ecNumber evidence="1">3.8.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">2-haloalkanoic acid dehalogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Halocarboxylic acid halidohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">L-2-haloacid dehalogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an (S)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11192"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:58314"/>
            <dbReference type="ChEBI" id="CHEBI:137405"/>
            <dbReference type="EC" id="3.8.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.</text>
    </comment>
    <dbReference type="EC" id="3.8.1.2" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171229.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2705"/>
    <dbReference type="EnsemblBacteria" id="BAF88703">
        <property type="protein sequence ID" value="BAF88703"/>
        <property type="gene ID" value="AZC_2705"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2705"/>
    <dbReference type="eggNOG" id="COG1011">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045011_3_2_5"/>
    <dbReference type="OMA" id="WIERGEE"/>
    <dbReference type="OrthoDB" id="1204073at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018784">
        <property type="term" value="F:(S)-2-haloacid dehalogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006328">
        <property type="entry name" value="2-HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01428">
        <property type="entry name" value="HAD_type_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU368077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="241" mass="26906" checksum="C1E5BE00F7E32CE2" modified="2007-12-04" version="1">MQLTDFTTLTFDCYGTLIDWETGIWNALQPLLSEGRLTIGREEALETFARHETEQEIETPSLRYSALLAVVHARLARAWGLHVHADLHERFGASVPDWPTFPDSAAALAYLKRHYKLVILSNVDRTSFAASNRKLGVAFDAIYTAEDIGSYKPDDRNFAFLLAHLEAELGVKPGQVLHTAQSLHHDHVPAERAGLARAWIDRRFGQSGSGATLPTERQPQVDFHFRTLGELADAHRKLVAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8Z9</accession>
    <name>A8I8Z9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AroM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">aroM</name>
        <name evidence="1" type="ordered locus">AZC_2726</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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    <dbReference type="OMA" id="NTHTIES"/>
    <dbReference type="OrthoDB" id="1880900at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017847">
        <property type="entry name" value="T6SS_RhsGE_Vgr_subset"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006533">
        <property type="entry name" value="T6SS_Vgr_RhsGE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01646">
        <property type="entry name" value="vgr_GE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03361">
        <property type="entry name" value="VI_Rhs_Vgr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="3">
        <location>
            <begin position="390"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="680" mass="74061" checksum="C9689EA7D79C18AF" modified="2007-12-04" version="1">MSDASAPVQTDRLLTLTTPLGGDVLIATHLEGKEGLSELFLFTLTMTSTKADITPDSLLGKPITVAIARPGGDPRYINGIVTRFQAGDRTVDGMRRYRVELSPKLWLLTRTSDCRIFQNQSVVQIADTLLSEGGITDYKKQGLSGSHPSRDYCVQYRETDYAFLQRIFAEEGIYFYFQYDSSSHTLVLSDSTAGYVDSIDKSVIHAPVTTGETIAVQEWASGFHFRSGKATLNDYNFEQPANDLTASTTTVLDNSAFKSWELYDYPGDYDTKDKGTPLSRLRMEAEEVDYAVSPGASTYAGFLPGAKFTMSKHEVVSEQGRSYALRTVEHSAQDLSHLGNQSGSVFYRNRFTALPAATAFRPPRITRRPLIPGPQTALVVGPSGEEIYCDKYGRIRLQFYWDRLGKKDENSSCWVRVAQSLAGSSWGTQFTPRIGMEVVVIFLEGDPDRPLVVSAVYNGQNMPPYTLPDNKTQSGIKTRSSPQGSASTFNELRFEDKKDSELVYMHAQKDFTREVTNDDTLTVSHDQTITIKNNRTETVQEGNESVTISKGNRTLTVSEGNDSLTVTKGNRSATISEGNDTLTLAKGNVTTTLNGGNHTLKLDSGNATMQCDGGSITLQAAQTITLKVGGNSITISQSGISLSGTQITISGSAKVQVSGSMVNVSGDGTVQVKGGLVTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="100" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB43</accession>
    <name>A8IB43_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="10">4.1.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Hydroxymethylpyrimidine phosphate synthase</fullName>
            <shortName evidence="10">HMP-P synthase</shortName>
            <shortName evidence="10">HMP-phosphate synthase</shortName>
            <shortName evidence="10">HMPP synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Thiamine biosynthesis protein ThiC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">thiC</name>
        <name evidence="13" type="ordered locus">AZC_2607</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + CO + formate + 3 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:24840"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:17245"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58354"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.99.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ThiC family.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2607"/>
    <dbReference type="EnsemblBacteria" id="BAF88605">
        <property type="protein sequence ID" value="BAF88605"/>
        <property type="gene ID" value="AZC_2607"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2607"/>
    <dbReference type="eggNOG" id="COG0422">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013181_2_1_5"/>
    <dbReference type="OMA" id="TWELFRD"/>
    <dbReference type="UniPathway" id="UPA00060"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025747">
        <property type="entry name" value="ThiC-associated_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="PTHR30557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13667">
        <property type="entry name" value="ThiC-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ThiC-associated" evidence="12">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="335"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="376"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="91"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="483"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="563"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="566"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF88605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="618" mass="67512" checksum="9F52B60312A83CCE" modified="2007-12-04" version="1">MKEIRMLDEASTSALKVTTGPLPHSRKVFIPAENPAVKVAMREIGLSDPSERPVRVYDTSGPYTDPNAIIDLTKGLPELRRQWVLDRGDVEEVEGRAQKPEDDGLKPGQVSHLPAFDRTGRKPLRAKAGKRPTQMAYAKAGIVTPEMEYVAARENLARANGGAHPKHQAMGLGAAIPADITGEFVRQEVARGRAIIPSNINHLETEPMAIGRNFLVKINANIGNSAVTSGVAEEVDKLVWAIRWGGDTVMDLSTGKNIHTIREWIIRNAPVPIGTVPIYQALEKVNGVVEDLNWEIFRDTVIEQAEQGVDYITVHAGVRLPYIPLTANRVTGIVSRGGSIMAKWCLAHHKESFLYEHFEELCEILAQYDVAFSLGDGLRPGSIADANDAAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMHLIRENVEKQLKLCHEAPFYTLGPLVTDISPGYDHISSAIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKAGVISYKIAAHAADLAKGHPAARIRDDALSRARFSFRWRDQFALSLDPETAEAYHDETLPAEGAKVAHFCSMCGPKFCSMKISQELKIEAGDIAQSGMAEMAEKFRASGGEIYQPAPDVAAPPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBM0</accession>
    <name>A8IBM0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171615.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3091"/>
    <dbReference type="EnsemblBacteria" id="BAF89089">
        <property type="protein sequence ID" value="BAF89089"/>
        <property type="gene ID" value="AZC_3091"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3091"/>
    <dbReference type="eggNOG" id="COG1574">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009942_4_3_5"/>
    <dbReference type="OMA" id="CRGWMHS"/>
    <dbReference type="OrthoDB" id="751534at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="52"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="623" mass="68458" checksum="47BF63BF9685D123" modified="2007-12-04" version="1">MTADLILHNGKITTLDRTNPVASAVAIKDGTFLAVGTDAEAMAHAGPTTRKVDLKGRSVLPGLIDNHLHIIRGGLNFNMELRWDGMRSLADAMDMLKRQVAVTPPPQWVRVVGGFTEHQFAEKRLPTIAELNAVAPETPVFILHLYDRALLNAAALRAVGYTKDTPEPPGGEITRDAAGNPTGLLLARPNAAILYATLAKGPKLPFDYQLNSTRHFMRELNRLGVTGAIDAGGGFQNYPDDYAVIQKLADDNQLTIRLAYNLFTQKPKQEKEDFLNWTKTSKYKQGSDYFRHNGAGEMLVFSAADFEDFREPRPDMPPEMEGDLEGVVRILAENRWPWRLHATYDETISRALDVFETVNKDVPLAGLNWFFDHAETISERSIDRIAALGGGIAVQHRMAYQGEYFVERYGAAAAEATPPVARMLDKGVKVSAGTDATRVASYNPWVSLSWLVTGQTVGGLRLYPRHNCLDRETALRMWTEKVTWFSNEEGRKGQIVAGQFADLIVPDRDFFSCPEADIAHMSSDLTIVGGKVVYGAGDFKALDDTPLPPAMPDWSPVRTFKGYAAWGEPEGAGKNSLRMAAACGCANSCGVHGHQHANAWSSRLPVSDLRSFWGALGCACWAV</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBS1</accession>
    <name>DXS_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="1">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="1">DXP synthase</shortName>
            <shortName evidence="1">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dxs</name>
        <name type="ordered locus">AZC_3111</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="1">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171635.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IBS1"/>
    <dbReference type="SMR" id="A8IBS1"/>
    <dbReference type="STRING" id="438753.AZC_3111"/>
    <dbReference type="PRIDE" id="A8IBS1"/>
    <dbReference type="EnsemblBacteria" id="BAF89109">
        <property type="protein sequence ID" value="BAF89109"/>
        <property type="gene ID" value="AZC_3111"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3111"/>
    <dbReference type="eggNOG" id="COG1154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009227_1_4_5"/>
    <dbReference type="OMA" id="QVGYHAQ"/>
    <dbReference type="OrthoDB" id="566385at2"/>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_1000071993" description="1-deoxy-D-xylulose-5-phosphate synthase">
        <location>
            <begin position="1"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="151"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <sequence length="641" mass="68121" checksum="CF49AAB6CF0AFA0E" modified="2007-12-04" version="1">MTVTKTPLLDTVRDASDVRRLPEEKLSQLADELRAETISAVSVTGGHLGAGLGVVELTVALHHVFNTPHDRLIWDVGHQCYPHKILTGRRDRIRTLRQGGGLSGFTRRSESEYDPFGAAHSSTSISAGLGMAVARDLSGGDRNVIAVIGDGAMSAGMAYEAMNNAGAMDSRLIVILNDNDMSIAPPTGAMSAYLARLISGRTYLSLREIGKQLAGHLPKFVKDGAAKAEEFARGFWTGGTLFEEMGFYYVGPIDGHNLEHLLPVLKNVRDAKTGPILVHVVTQKGKGYPPAEASADKYHGVVKFDVVTGAQVKAKSNAPSYTRVFAETLIDEARRDDKVVAITAAMPSGTGLDLFGQAFPQRTFDVGIAEQHAVTFAAGLAAEGYRPFCALYSTFLQRGYDQVVHDVALQGLPVRFAIDRAGLVGADGATHAGAFDLAMLTCLPGFTVMAPADEAELTHMIATAVGHDAGPIAFRFPRGEGVGVERPEKGERLPIGKGRVVREGQDIAFLSLGTRLAACLDVAERLSSLGISATVADARFAKPIDRELIAHLARTHAALVVVEEGSVGGFGSQVLQFLSDEGLMDGGLKVRALTLPDTYIDHDTPAAQLAEAGLDADGIYKRALALVQPAERRGAVATKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBZ3</accession>
    <name>A8IBZ3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase J</fullName>
            <ecNumber evidence="1">2.1.1.266</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (adenine(2030)-N6)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m6A2030 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmJ</name>
        <name evidence="2" type="ordered locus">AZC_3139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the adenine in position 2030 of 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(2030) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(2030) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43736"/>
            <dbReference type="Rhea" id="RHEA-COMP:10668"/>
            <dbReference type="Rhea" id="RHEA-COMP:10669"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.266"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RlmJ family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.266" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171663.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3139"/>
    <dbReference type="EnsemblBacteria" id="BAF89137">
        <property type="protein sequence ID" value="BAF89137"/>
        <property type="gene ID" value="AZC_3139"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3139"/>
    <dbReference type="eggNOG" id="COG2961">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061769_0_0_5"/>
    <dbReference type="OMA" id="TYAIWYP"/>
    <dbReference type="OrthoDB" id="1186316at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036307">
        <property type="term" value="F:23S rRNA (adenine(2030)-N(6))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00934">
        <property type="entry name" value="23SrRNA_methyltr_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007473">
        <property type="entry name" value="RlmJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37426">
        <property type="entry name" value="PTHR37426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04378">
        <property type="entry name" value="RsmJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="145"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="1">
        <location>
            <position position="3"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="283" mass="31040" checksum="0AF517D36A97D820" modified="2007-12-04" version="1">MNYRHAFHAGNPADVMKHATLARVLTYLAKKDNAYRVIDTHAGAGLYDLAGTSAMKTGEAEAGIERVLAADLPEPVAQLLEPYLGAVRTLRETAGPRRYPGSPALALALGRPQDRFLFCELHGEERQKLEKAVGHDARAKVLSQDGWKAVAAHLPPRERRGVLLIDPPFEEAGEFGRLTAALETAAQRFATGVVMLWYPIKDLMTVDAFRRDVARLGLPKTLRVEIDFAEVRSQSQLSGSGLIILNPPFTLAEEMRTILTAINPLMARDGKGRVRVSWLTQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC11</accession>
    <name>A8IC11_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cell inner membrane</location>
            <topology evidence="2 10">Single-pass type II membrane protein</topology>
            <orientation evidence="2 10">Periplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the COX11/CtaG family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171480.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2956"/>
    <dbReference type="EnsemblBacteria" id="BAF88954">
        <property type="protein sequence ID" value="BAF88954"/>
        <property type="gene ID" value="AZC_2956"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2956"/>
    <dbReference type="eggNOG" id="COG3175">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045000_5_0_5"/>
    <dbReference type="OMA" id="NKLECFC"/>
    <dbReference type="OrthoDB" id="1821272at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008535">
        <property type="term" value="P:respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00155">
        <property type="entry name" value="CtaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023471">
        <property type="entry name" value="CtaG/Cox11_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007533">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_CtaG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04442">
        <property type="entry name" value="CtaG_Cox11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005413">
        <property type="entry name" value="COX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110111">
        <property type="entry name" value="SSF110111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0186">Copper</keyword>
    <keyword evidence="9 10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="topological domain" description="Cytoplasmic" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="topological domain" description="Periplasmic" evidence="10">
        <location>
            <begin position="51"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF88954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="215" mass="23016" checksum="EAA34524FDC8BD79" modified="2007-12-04" version="1">MDTRETAEKTAGAEPSADVSRAPRASRRNGRVVVGCVLFVAAMVGVTYASVPLYRAFCSMTGFGGATRTAEGAATKVLDRKITVRFDGNVAPGLPWDFRPEATSTEVKVGETSMAYYFAASRGRSETYANATYNVMPSTAGAYFVKLQCFCFNEQKLEAGEKVDMPVVFYIDPAIADDPEMDGLTTITLSYTFFPAAKPAAAQAAAPAPKQKVPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IE05</accession>
    <name>A8IE05_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">Arginine/lysine/ornithine decarboxylases</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3019</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-I family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171543.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3019"/>
    <dbReference type="EnsemblBacteria" id="BAF89017">
        <property type="protein sequence ID" value="BAF89017"/>
        <property type="gene ID" value="AZC_3019"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3019"/>
    <dbReference type="eggNOG" id="COG1982">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014292_3_0_5"/>
    <dbReference type="OMA" id="MKGRSGE"/>
    <dbReference type="OrthoDB" id="485164at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005308">
        <property type="entry name" value="OKR_de-COase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011193">
        <property type="entry name" value="Orn/lys/arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008286">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036633">
        <property type="entry name" value="Prn/Lys/Arg_de-COase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03711">
        <property type="entry name" value="OKR_DC_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03709">
        <property type="entry name" value="OKR_DC_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009393">
        <property type="entry name" value="Orn_decarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55904">
        <property type="entry name" value="SSF55904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00703">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OKR_DC_1" evidence="4">
        <location>
            <begin position="388"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR009393-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="785" mass="88476" checksum="31A9857B28CF9B17" modified="2007-12-04" version="1">MDYFRRFTFLFATPAFDADDLEGVRLNQIVDEIGRAGFEVVMARDLDDAQIAVQTDAAIGCMLIDWGKKGLEGKTAALINLMRKRGLDFPIILLVRRKRFEDLPVEVLDFIDGYVFLSEETPAFIAKNLVSRLKQYAETLKTPFFGALVDYAEEGNQLWTCPGHNGGVFYSRSPIGRVFMEHLGEAVFRDDLDNSVLDLGDLLTHEGPALQAQKEAAKIFGAEKTYFVLNGTSTSNKVALSALVTDGDLVLFDRNNHKAAHHGALLIGGGIPVYVPTVRNAWGLIGPMRWDKLDETALREAIRTNPLVSDPDAWQRPRPFRVAVVEQCTYDGTIHNAEMILKRIGHLCDYILFDEAWAGFMKFHPLYAGRYAMGLSDLGPDSPGIIATQSTHKQLASFSQASQIHMKDRHITGQKRRVEHRRFNESFMQHASTSPFYPLFASLDVGAQMMKGRSGEVLWDDTIRLGIELRKKIRASRREFEEKESRPERRWFFEPFVPERVAIPDAARPGAFHDVPWESVGTDQLATDPAFWQLAPEAKWHGFGDLAPGFAMTDPNKLTLLTPGFDRTTGDYTEHGIPAPVVAQYLRENRIVPEKNDLNSLLFLLTPGVEASKAGTLISGLVAFKRLHDDNALLEDAIPEFFRRRPQRYAGVRLRDLCGEMHRFFREANVSRLQAQQFCPEHLPEMAMSPHDAARCLVRNDVDYLPIDAISGRIATTPFVVYPPGIATIVPGERLTERAQPMIDYLRMFEASFNTFPGFEVEIQGVYREIDATGRVRLYTYVVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEC2</accession>
    <name>A8IEC2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3473</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171996.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3473"/>
    <dbReference type="EnsemblBacteria" id="BAF89471">
        <property type="protein sequence ID" value="BAF89471"/>
        <property type="gene ID" value="AZC_3473"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3473"/>
    <dbReference type="eggNOG" id="COG4122">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079350_0_0_5"/>
    <dbReference type="OMA" id="MQPYFLP"/>
    <dbReference type="OrthoDB" id="1451657at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014985">
        <property type="entry name" value="WbqC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08889">
        <property type="entry name" value="WbqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="241" mass="26710" checksum="5788DC94A42C927F" modified="2007-12-04" version="1">MTAVVITQPMLFPWPGFFEQLMLADAYLYLDDAQFSKGSFTNRIQVKYGDDRRWMTIPLAGKGSFQPIAELKATDGDWKSAHRALLAQSLADAPHRDDALGLLDAAYAHDDLCDLLIASIEEPARYLGIGSGRDIGRTTACKVEGTSWQRVLDLVLDQGGTRYLTGHGAARYLDHDAFEAAGVGVEYMAYSLTPWPQGKGAFTPYVTILDLIAHTGRDAITYLRPATVAWRPFLEQRRENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEE3</accession>
    <name>A8IEE3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glucose-1-phosphate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172003.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3480"/>
    <dbReference type="EnsemblBacteria" id="BAF89478">
        <property type="protein sequence ID" value="BAF89478"/>
        <property type="gene ID" value="AZC_3480"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3480"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_10_0_5"/>
    <dbReference type="OMA" id="YWRAIDT"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047343">
        <property type="term" value="F:glucose-1-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02524">
        <property type="entry name" value="G1P_cytidylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013446">
        <property type="entry name" value="G1P_cyt_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47183:SF1">
        <property type="entry name" value="PTHR47183:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02623">
        <property type="entry name" value="G1P_cyt_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="257" mass="28693" checksum="108B1AD8DDA44EDC" modified="2007-12-04" version="1">MKVVILAGGRGSRLSEETSVRPKPLVEIGDKPIIWHIMSIYAHHGFNEFIVCAGYKGYQIKEYFANLVLHHSDVTVDLGRNLVHYHQSDKPNWRVSIVDTGLDTMTGGRLKRVRPYLTPGEPFLMTYGDGVADVDVAQEVAFHKAHGLKATMCAVAPPGRFGSANIEGNKVSSFVEKPTAGNQRINGGFFVLEHDVLDLIDNDDTVWEAEPLESLVAEGQLAAFPHDGFWRPMDTLRERTQLDELWNSGRAPWKVWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>A8IF98</accession>
    <name>A8IF98_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172117.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3594"/>
    <dbReference type="EnsemblBacteria" id="BAF89592">
        <property type="protein sequence ID" value="BAF89592"/>
        <property type="gene ID" value="AZC_3594"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3594"/>
    <dbReference type="HOGENOM" id="CLU_2821805_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="66" mass="7537" checksum="7F82CF5ECD24B39A" modified="2007-12-04" version="1">MEPEAYHHPDIICQRATALAELAATVDNTKNRQAREHLLDFMERICRTLQPPRPAELKVINGTPDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFM0</accession>
    <name>A8IFM0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">6-phosphogluconolactonase</fullName>
            <shortName evidence="7">6PGL</shortName>
            <ecNumber evidence="5 7">3.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgl</name>
        <name evidence="9" type="ordered locus">AZC_3630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12556"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="3.1.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.31" evidence="5 7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172153.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3630"/>
    <dbReference type="EnsemblBacteria" id="BAF89628">
        <property type="protein sequence ID" value="BAF89628"/>
        <property type="gene ID" value="AZC_3630"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3630"/>
    <dbReference type="eggNOG" id="COG0363">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053947_2_1_5"/>
    <dbReference type="OMA" id="YQLFEFE"/>
    <dbReference type="OrthoDB" id="1828393at2"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017057">
        <property type="term" value="F:6-phosphogluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01400">
        <property type="entry name" value="6PGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005900">
        <property type="entry name" value="6-phosphogluconolactonase_DevB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006148">
        <property type="entry name" value="Glc/Gal-6P_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039104">
        <property type="entry name" value="PGLS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11054">
        <property type="entry name" value="PTHR11054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01182">
        <property type="entry name" value="Glucosamine_iso"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01198">
        <property type="entry name" value="pgl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucosamine_iso" evidence="8">
        <location>
            <begin position="19"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00020337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF89628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="241" mass="25300" checksum="F035A185E0190279" modified="2007-12-04" version="1">MTETAPGELLPVAFTAYEDRAALARALAAHVAEALRRRLATDGRAALAVSGGRTPTLFFETLSGAPLDWAKVSVTLVDERWVPETSDRSNAALVRAHLLRGPATAARFVPLYTGAPTPEEGLTAAHAAIADLPQPFAAVVLGMGDDAHTASFFPGADTLATAIDPRTDAKLITARAPAAGEPRITFTIGPLIGADALFLHIEGAGKKAVLDAAREPGDPMERPIRAILLHSPRPLDVLWCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG15</accession>
    <name>A8IG15_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_0016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168547.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0016"/>
    <dbReference type="EnsemblBacteria" id="BAF86014">
        <property type="protein sequence ID" value="BAF86014"/>
        <property type="gene ID" value="AZC_0016"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0016"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_2_5"/>
    <dbReference type="OMA" id="GMHYRQS"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="300" mass="32841" checksum="E94E6DA3D690C9CE" modified="2007-12-04" version="1">MFVRQLHYLVAVAREQHFGRAAEACHVTQPTLSAGLRKLEEELGYPLVVRGHRFMGLTEHGARVLAWAQRIINDYDGMRQELAGSEAGLTGILRLGCVPPMLPALSGLLTAFCERHPLVRVQALSMSALAIQRGLDDQVLDAGVSYLTGTQPPKLHWLPFYEERYMFVRAAGGDDLPARISWAEAARSPLCLLTPDMQNRQIIDEALATAGAVSVPRIEANTFFGVWSMVCSGAWASIVPHTHIATFGRMAGVCAIPLIDPDWRRPVGLVTPDRDPLAPVAAAFRKLAARWSWNGEDAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGG3</accession>
    <name>A8IGG3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative branched-chain amino acid transport protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">azlC</name>
        <name evidence="9" type="ordered locus">AZC_0085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168616.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0085"/>
    <dbReference type="EnsemblBacteria" id="BAF86083">
        <property type="protein sequence ID" value="BAF86083"/>
        <property type="gene ID" value="AZC_0085"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0085"/>
    <dbReference type="eggNOG" id="COG1296">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065777_2_1_5"/>
    <dbReference type="OMA" id="DFAFPAV"/>
    <dbReference type="OrthoDB" id="1866750at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF86083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="238" mass="25058" checksum="5F56171FCEC4F1B6" modified="2007-12-04" version="1">MPHSPKDHVSVTAHGMMEGARVMIPLMPGLVLFGMAFGAAAAQKGFSLLEASLSSGLVFAGLAQMVALEGWTKTWTPGGLLALAFLTMAVNMRHFLMSASMRPWLGQLPGWKAYPSLLLMADNNWAAAMRYRANGGSDAGFFIGSGIITWFVWVASTAAGQVIGGGLPDPKKFAIDVVVPAFFVAMLVPNWKGRREAVTWGVAAAVSVGASFLLPGWWFIVIGAVAGAVAGGFADDKR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0099"/>
    <dbReference type="EnsemblBacteria" id="BAF86097">
        <property type="protein sequence ID" value="BAF86097"/>
        <property type="gene ID" value="AZC_0099"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0099"/>
    <dbReference type="eggNOG" id="COG0647">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
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        <property type="entry name" value="HAD-SF_hydro_IIA"/>
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        <property type="entry name" value="HAD-SF_hydro_IIA_hyp3"/>
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        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="348" mass="36948" checksum="51FC5996C0C68651" modified="2007-12-04" version="1">MHPPRLTCLPAQGGCARLGLVKPGAAWHLTGAPGRSLRRGTGSPLPPRRGDGFMNDVAPPRSALPLLSGFSEIAGNYDLILCDVWGVIHNGVSAFPAACHALEQVRATGASVFLVSNAPRPNAFVMAMLDGMGVPRTSYDGIVTSGDVTRSVLADRPGARMFHLGPARDLGTYEGLDLVHTPLGEAELVVCTGLLNDDVETPDDYRPMLEQMRARDLAFVCANPDIVVERGDRLIYCAGAIAQLYDELGGSSLYCGKPHPPIYAEALKRTLTVRDSVPVPSRILAIGDALRTDVTGAAGAGFDSLFISSGIHAIELRSEHGAPPDMELVEQLFAAGPRPNAVMPRLSW</sequence>
</entry>
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    <reference evidence="4 5" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="CAZy" id="GH103">
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        <property type="protein sequence ID" value="BAF86162"/>
        <property type="gene ID" value="AZC_0164"/>
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    <dbReference type="KEGG" id="azc:AZC_0164"/>
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        <property type="entry name" value="Lysozyme-like_dom_sf"/>
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        <property type="entry name" value="MltB-like"/>
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        <property type="entry name" value="MltB_2"/>
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        <property type="entry name" value="Peptidoglycan-bd-like"/>
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        <property type="entry name" value="PGBDSf"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
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    </dbReference>
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    <dbReference type="TIGRFAMs" id="TIGR02283">
        <property type="entry name" value="MltB_2"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721018" evidence="1">
        <location>
            <begin position="45"/>
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        <location>
            <begin position="82"/>
            <end position="375"/>
        </location>
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    <feature type="domain" description="PG_binding_1" evidence="2">
        <location>
            <begin position="397"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF13406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="453" mass="49708" checksum="6AF1B93E86D26C71" modified="2007-12-04" version="1">MMAVKTTRSTRMAARTGRTTARGLAAAFAAAVSLVAVAPAGAQAQVTGSIFSGFQPQQPPAPERAGHPLMQPEAIAQAQANFPNCIAALQPLAQSKGVSPASFQRLTAGLEPDMKIMDYLDSQPEFSKTLGDYVTMLVSQTRITKGREMLEKYKPIFEKVEKAYGVDRYVVAAIWGIETSYGDPKGIGTRSVLRSTATLACIGRRQDYFRDEFIATLQIIDRGDVPADHMKGSWAGAFGPTQFMPTSFLRYAVDFDGDGHRNVVDSIPDVIASTANNLKLDGWQFGQTWGYEVVLPQNFDYRYVDRTKRYSMAQWASLGIRRANGQAFPRPSDTGFLLLPSGAKGPAFIMLPNFGAILRYNPADAYALAIGHLADRLRGGGDFVQAWPKEERALSRTERLELQTRLSQMGYDIGNIDGILGQKTRVAVQDFQTRAGMIPDGYPNLDVLARMRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH99</accession>
    <name>A8IH99_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
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        <name evidence="6" type="ordered locus">AZC_0193</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168724.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0193"/>
    <dbReference type="EnsemblBacteria" id="BAF86191">
        <property type="protein sequence ID" value="BAF86191"/>
        <property type="gene ID" value="AZC_0193"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0193"/>
    <dbReference type="eggNOG" id="COG4191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_1_5"/>
    <dbReference type="OMA" id="YLAVQME"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="138"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="358" mass="37946" checksum="DE7138DAA402C8BF" modified="2007-12-04" version="1">MLGATLSRTVSVSRSWVVLAMLIALMTAIFVVDTVTNYAVAAAVLYTAVQLIATRFLSVRTVIILTGASIVLTLLSFELTRSGAYEVGVVNTAISVVVIGVTAYLGLKLKSAQQSADETRERLLRMARLMTLSQLTTSIAHEVSQPLAGIATSASASRRWLTQQPPNVERALAAIERVASDACRANDVLARVRGMARREATSKASFDFNEAVREVLDLAGGDMLRTGAQVSLSLAENLPAAFADRVQIQQVIGNLVLNAMEAVSALPNRLPRLTISTALEPAGMISFSISDNGPGVSPDTAQHLFDAFWTTKEQGFGLGLTICQTIVEANGGRIWMLPAPPEAGATFVFNLPTAGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHJ1</accession>
    <name>A8IHJ1_AZOC5</name>
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        <submittedName>
            <fullName evidence="10">Amino acid ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_3283</name>
    </gene>
    <organism evidence="10 11">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3283"/>
    <dbReference type="EnsemblBacteria" id="BAF89281">
        <property type="protein sequence ID" value="BAF89281"/>
        <property type="gene ID" value="AZC_3283"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3283"/>
    <dbReference type="eggNOG" id="COG0765">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_1_0_5"/>
    <dbReference type="OMA" id="AMYLVIT"/>
    <dbReference type="OrthoDB" id="1523519at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="21"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="227" mass="25222" checksum="F12C358D78FB0D41" modified="2007-12-04" version="1">MTYQFDFAVLLPFWREFAMGVWLTLQLSLISTVLGFILGTLCAIGRADGPPWVKFLVATYVEIIRNTPLLVQVFIVYFGIATLGIHVSANLAAVLALVVNVGAYTSEIVRAGLESIHKSQLEAAECLGLSRPQTYWHVIVRPAIERVYPALTSQYVLLMLASSITSQISAEELTAVANRIQSDTFRSFETYIVVGVLYLALSFVVRLAFWLFGLVVFVRRRKLGTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHQ0</accession>
    <name>A8IHQ0_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">Secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hlyD</name>
        <name evidence="5" type="ordered locus">AZC_3306</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3306"/>
    <dbReference type="EnsemblBacteria" id="BAF89304">
        <property type="protein sequence ID" value="BAF89304"/>
        <property type="gene ID" value="AZC_3306"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3306"/>
    <dbReference type="eggNOG" id="COG0845">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_2_1_5"/>
    <dbReference type="OMA" id="ATINLGY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="147"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="459"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="187"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="487" mass="51419" checksum="186C62EF6CEF162F" modified="2007-12-04" version="1">MNGSAACQCERPENTARRHFVTVASERERGRGRIRAAFRQGGVSSGRYSGMAVSWTGPGALLTLAPGEGRGSIMTVWAWVAGVRGAAFEGRSVKVVAPALAALALAGCNEQNTYVAPPPPTVTVAPAPEQSVVRYLELTGNTASINTVDLNARVQGFLTSINYKDGAMAKKGDLLFVIEQDQYKADVAQAQATLAAKQAAQVQAEAEFNRQNQLAKQDFASQATLDQARAKRDGAVADVQNAQASLDLAKINLGYTEVRAPFDGVVTAHLQDVGALVGYGSPTKLATIVEINPIYVWFSLSETQVLRIKDALAQQGKTLRSIEGQLADIPVEIGLQTEQGYPHVGHLDYVAPQVDANTGTLTVRGIFDNKDLSLLPGLFARVRLPLGASTDMVLVADAAIGTNQSGSYVLTVGSDGIVKQQTVQLGQMQAEGLRAITSGLAKGDQVVVNGLQRAVPGSKVTVEKGQMVNESAKPKPPIDPSKPAPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHT9</accession>
    <name>A8IHT9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">expE6</name>
        <name evidence="2" type="ordered locus">AZC_3321</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_3321"/>
    <dbReference type="EnsemblBacteria" id="BAF89319">
        <property type="protein sequence ID" value="BAF89319"/>
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    <dbReference type="KEGG" id="azc:AZC_3321"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_379434_0_0_5"/>
    <dbReference type="OMA" id="RICRPRY"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
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        <property type="entry name" value="SSF53448"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89319.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="743" mass="79505" checksum="486742E2B561B60E" modified="2007-12-04" version="1">MPDPHAPDRPSTDRPAERGEIHGLPLDGETALVAAVDEGLALIAGMGEMPASVQALLNGDPSAATQAATVSWRRPEAPPEARSGFCALVPLAVLGRGRLTSIVFRRPGHPARYAFARRPVPLEAALQAIAEDAGPSAALVVDGIVEALLAGKPTARRLRAVAAMAQAVARPDGFVEVMGADEDGELFLQGWTADLVPGRARVLAIGTEPMLAELDSASFPREDLAGRSRGFAGVMTGAEKIDAAALQKVLFRSREGWRAITVYERCVRLEPRDVPAHARAVLPRLTAPTDVLARLKAAANRFDGRDTVSELKLPVRLGIDFALMVDGGGVLVSGWIVDCEEHVEAVHLKVGKTGVRIDEGWTRQPRPDVTRAFASDPLFAALDPGHHGHGFLAFAPRVAAHARDAAYLELTLASGPVYRPLPLTRATPRHVLQRLSTAVEPRSAVAAQVVERQLGPLVQTLERRPASGRVMSEAGGFEGSASMALVIGVDEGAAQVGVLLSLLALEPETRALPIVVAVREEWFDEVSAEVRRLADFYRLSLRLVRAEGAQDVCDAIEAGVRASSAEHLLLMCAHVLPRGSGWLPQLERAYRARGGRCLVSPTLLFEDDSIRWAGTMLQGEGTGRGLSDRLVGYPRAAVAEADPMEVTAGTVECCILPRAAFESVEGFTRGYLGIAEKRLDLALKLRLGGTPSVWVPEVEMICADETSEGAAGPAVASWHGLVRKVDRWAFDRRWSLAVANMRS</sequence>
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    <accession>A8IHY8</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="BAF89337"/>
        <property type="gene ID" value="AZC_3339"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
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        <property type="entry name" value="TF_FadR/GntR_C"/>
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        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
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    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
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        <property type="entry name" value="WH_DNA-bd_sf"/>
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    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
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    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="29"/>
            <end position="96"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
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    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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        <source>
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    <evidence type="ECO:0000313" key="5">
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="244" mass="26795" checksum="B899517D08251653" modified="2007-12-04" version="1">MQAPHLYGSMDELATGRMNVDALNVPTTGSTAQRIETELRRAIISMSLPPGTRLSEQEIATSHGVSRQPVREALIGLARTRLVEILPQRGTVVVKISTRKMMEARFVREAIETAVARKAADAFDPAQRTRIDDLIDLQSKAAQRNDHGTFQRYDELFHVALAEGAGCGLAWEAISDIKAHMDRACHLTLTSAETMAALVDQHRAIMVAVDARDPAGAAEAMRCHLSEILRALPKVAQEHPDLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
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    <sequence length="725" mass="78249" checksum="164003BA004691A8" modified="2007-12-04" version="1">MNGLFAQLSGGHLLPADFHFLRPDWLLALLPALVIAALVWKRMGTGQSAWAGLVDAHLLRHLALTDRSRAGRWPVFALLAAYALAILAMAGPAWQKLPTPALDRIDPTVVVLSLAQSMNATDQNPTRLAAARHKVEDILNRMRGGQVALIVFADAPFVAAPLTEDARVVQQMLPEIGTDLMPVMDNRPDIAIRQAIDLLKNTGAPTGRIILIGDGLGDRPEQTKATAASAGNAGYHVSVIGVGRDAPTPLVAFDGRPLTGRDRTPLTTRMDEAGLKDVAIAGRGVFTPLTVGDRDIDTILAQSGVDGPAKPGELQDSGLAADQWADMGPFVLLVVVALFAPLAFRRGWIAILLLGLLAGAAPLAPARAQEPSLSERWRDLWQTPDQQAAAAFKSQDYQGAAARFANPDWQASALYKAGDYEKAAEAYSRLPNGAYNQANALARAGKLDDAVKAYDEALKQNPDNADAIYNRNLVQKLIDDQKKMDLPQPPPQDQQNKDNKNGGGNQQDKQQQDKQDKGDNKQNTPQNQKDQKDQNKKDQGQQDQKDKKPDGDDEGKQKPDPKSGPQPQQAQPKPDPGQKNQPQQGQDQKDQPKPQPKDQGNDPAKADPKDGKDANKPDQKDGKEAPKPDPRAPGNTPAQPQPAQPNPQGQPGQQPQPQPAQPAQQGGDQPGMALTPLGLRPMTPEDQNREQALRMVPDDPMGLLRARIRAHYTGRPPEVEGVNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIF0</accession>
    <name>A8IIF0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding component phosphonate transport</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">phnL</name>
        <name evidence="6" type="ordered locus">AZC_3398</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3398"/>
    <dbReference type="EnsemblBacteria" id="BAF89396">
        <property type="protein sequence ID" value="BAF89396"/>
        <property type="gene ID" value="AZC_3398"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3398"/>
    <dbReference type="eggNOG" id="COG4778">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="MHLRDGI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012701">
        <property type="entry name" value="CP_lyase_PhnL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02324">
        <property type="entry name" value="CP_lyasePhnL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="24"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="63"/>
            <end position="70"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="252" mass="26895" checksum="AEB87EDAD718F1A2" modified="2007-12-04" version="1">MTLHTAPQTAATPLPPALPAGTLLRVESLAKAFTLHLRGGARLPVVDGAGFEVRAGTCVALGGPSGAGKSSILKMVYGNYRTDAGAIWLMDETSPVDVAHAAPRQMLDLRRRRIGYVSQFLRVIPRVSALDVVAEPLMAEGVPPEQARAKARELLARLNLPERLWSLPPATFSGGEQQRVNVARGFISSRPLLLLDEPTASLDVVNRQVVIDLITEKKAAGTGLLGIFHDADTRDAVADEVVDVSAFATRPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIG1</accession>
    <name>A8IIG1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171925.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3402"/>
    <dbReference type="EnsemblBacteria" id="BAF89400">
        <property type="protein sequence ID" value="BAF89400"/>
        <property type="gene ID" value="AZC_3402"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3402"/>
    <dbReference type="eggNOG" id="ENOG50331XP">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_2520496_0_0_5"/>
    <dbReference type="OMA" id="DQGGYSW"/>
    <dbReference type="OrthoDB" id="2053010at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="84" mass="9135" checksum="AF2EDB129B99C5CD" modified="2007-12-04" version="1">MSDAAETLLSGAEYELLAGPGAGAYRLRCKPEQRVALLEGEDAARFRADLETVQQQFPGCTADQALAQLWDQGGYSWLAAEEEE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIZ0</accession>
    <name>HSLU_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent protease ATPase subunit HslU</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Unfoldase HslU</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hslU</name>
        <name type="ordered locus">AZC_0221</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ClpX chaperone family. HslU subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168752.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IIZ0"/>
    <dbReference type="SMR" id="A8IIZ0"/>
    <dbReference type="STRING" id="438753.AZC_0221"/>
    <dbReference type="PRIDE" id="A8IIZ0"/>
    <dbReference type="EnsemblBacteria" id="BAF86219">
        <property type="protein sequence ID" value="BAF86219"/>
        <property type="gene ID" value="AZC_0221"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0221"/>
    <dbReference type="eggNOG" id="COG1220">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033123_0_0_5"/>
    <dbReference type="OMA" id="KYGMIKT"/>
    <dbReference type="OrthoDB" id="718259at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009376">
        <property type="term" value="C:HslUV protease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036402">
        <property type="term" value="F:proteasome-activating activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043335">
        <property type="term" value="P:protein unfolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00249">
        <property type="entry name" value="HslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004491">
        <property type="entry name" value="HslU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF3">
        <property type="entry name" value="PTHR48102:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00390">
        <property type="entry name" value="hslU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_1000071850" description="ATP-dependent protease ATPase subunit HslU">
        <location>
            <begin position="1"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="60"/>
            <end position="65"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00249"/>
        </source>
    </evidence>
    <sequence length="435" mass="47600" checksum="76CAB510F60B3DBA" modified="2007-12-04" version="1">MSDFSPREIVSELDRHIVGQGKAKRAVAIALRNRWRRQQLQGHMREEVLPKNILMIGPTGVGKTEISRRLARLAGAPFLKVEATKFTEVGYVGRDVEQIIRDLVEVGIGLVREQKRKDVQARAHLAAEERVLDALVGANSSSTTRDAFRKKLRAGELDEKEVEIEVQAGAQGMPMFEIPGMPGAQMGAVSLGDMLGKAFGGRTKARRVLVKDAHPLLLTEEADKLIDQEATTQEAIYAVENNGIVFLDEIDKIAQREGRSGADVSREGVQRDLLPLIEGTTVSTKHGPVKTDHILFIASGAFHVSKPSDLLPELQGRLPIRVELEALTRADFVRILTETEASLVKQSVALMGTEGVTLDISPDAVEAIADVAVEVNSTVENIGARRLQTVMERVLDELSFTAPDRSGETVSIDAAYVRERVADLAKNADLSRFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ14</accession>
    <name>A8IJ14_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0233</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0233"/>
    <dbReference type="EnsemblBacteria" id="BAF86231">
        <property type="protein sequence ID" value="BAF86231"/>
        <property type="gene ID" value="AZC_0233"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0233"/>
    <dbReference type="eggNOG" id="ENOG5031VKS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1786154_0_0_5"/>
    <dbReference type="OMA" id="ATYGRAY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="164" mass="16885" checksum="538E20D15943D75F" modified="2007-12-04" version="1">MSGAPICLRPCPCAATLTLLNGSDKGGCRMSRTFSLAGMVSAVVVAGLVTPAQALLPPKYYDQARRQAANIIVLEVAAVAEPAEPFGTCAVSGHVRKVERGKLYAPGAAVTVGVPCRKPGAQPPLGGTIYADVGALRAATYGRAYLDARGNLLLSQYQMLATAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJA5</accession>
    <name>A8IJA5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <dbReference type="eggNOG" id="COG1051">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Nudix_hydrolase"/>
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        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
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        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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        <location>
            <begin position="6"/>
            <end position="137"/>
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        <source>
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    <sequence length="141" mass="14664" checksum="4E382E65E8071ABE" modified="2007-12-04" version="1">MSDPVRPTLAASAAVFRDGRVLLARRGKAPGAGLWSLPGGRVEPGERLAEAAAREVMEEVAVEAEILAVAAARDIIVRDGERLLAHFVVVAHAARWRAGEPTIGEEAIEVGWFAPDEVAALPGTDGLAEVVAAAARLMAAP</sequence>
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    <accession>A8IKY1</accession>
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        <name evidence="10" type="ordered locus">AZC_3964</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3964"/>
    <dbReference type="EnsemblBacteria" id="BAF89962">
        <property type="protein sequence ID" value="BAF89962"/>
        <property type="gene ID" value="AZC_3964"/>
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    <dbReference type="KEGG" id="azc:AZC_3964"/>
    <dbReference type="eggNOG" id="COG0664">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
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        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
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    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
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        <property type="entry name" value="CNMP_BINDING_3"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
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        <location>
            <begin position="12"/>
            <end position="31"/>
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        <location>
            <begin position="43"/>
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    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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            <begin position="141"/>
            <end position="171"/>
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        <location>
            <begin position="362"/>
            <end position="449"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="473" mass="49496" checksum="66116176337E3424" modified="2007-12-04" version="1">MLSAQIAQEVPWTILIVLGFPLLTVLLIELTRRFAGPDSAARRPIKALQMIVVPAGAVWIIVHELLHLPPEGLTVKIVDTAVGILLLHAVFTILQSLIIAFSETVGRLPAPRLFYELGSSAVVAIGAAIIVSTIWDVDLGSLLGALGIGSVVLGLALQNVIGGLVAGVIVFSGRHFNLGDWLQIDGTPAKVVQIDWRAITVETLSGERIVVPSANMSSASLRITRARQSVSVATDVSLPPGTAPAEAKALLLEAARDVPQLLDANAVACRVKQLGGTAIVYGVSFPVADASQVVKARDAFLHRLWYVGQRHGVSVAEGVSAEELYGTDTPQTRLAALAGTGAFGAVSDDLRVVAVDARLRLYAAGEIILRAGEAAPYFLVLLSGAARVSLPAGGVVERLADGALYATRDAFRGTPSSVEVLAESEVHLLEVPVTAMERLLERHPALAQRVDMIVEARTAALADSLAGNGGAAA</sequence>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILV3</accession>
    <name>A8ILV3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DSBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168954.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0423"/>
    <dbReference type="EnsemblBacteria" id="BAF86421">
        <property type="protein sequence ID" value="BAF86421"/>
        <property type="gene ID" value="AZC_0423"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0423"/>
    <dbReference type="eggNOG" id="COG3531">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097497_0_0_5"/>
    <dbReference type="OMA" id="LHYIYDP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="10"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="205" mass="21868" checksum="78DAE0B17A87CB21" modified="2007-12-04" version="1">MTIRLHYIHDPLCGWCYAAAPLAEAAAAVPGVEIVLHGGGLFPEPAQLAPAMVSHIRAADARIAQMTGQAFGRPYLDELLPDPALRLHSLPPIAAVMAAEELAGQGLGMHVAIQRAHYVDGKRVVEPETLADLAQGLGLDREGFVSALGRQPVADHLSQTRRLMARFGLGGFPGFVRESDGRFDVLPHTQLYGQPGKFADLLKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM01</accession>
    <name>A8IM01_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4 13">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">mutY</name>
        <name evidence="16" type="ordered locus">AZC_0456</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the Nth/MutY family.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4 13"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168987.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0456"/>
    <dbReference type="EnsemblBacteria" id="BAF86454">
        <property type="protein sequence ID" value="BAF86454"/>
        <property type="gene ID" value="AZC_0456"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0456"/>
    <dbReference type="eggNOG" id="COG1194">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012862_0_2_5"/>
    <dbReference type="OMA" id="RDPYRVW"/>
    <dbReference type="OrthoDB" id="1274533at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004035">
        <property type="entry name" value="Endouclease-III_FeS-bd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169029.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0498"/>
    <dbReference type="EnsemblBacteria" id="BAF86496">
        <property type="protein sequence ID" value="BAF86496"/>
        <property type="gene ID" value="AZC_0498"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0498"/>
    <dbReference type="eggNOG" id="COG0483">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_0_0_5"/>
    <dbReference type="OMA" id="RVDGYWE"/>
    <dbReference type="OrthoDB" id="1741160at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="262" mass="28646" checksum="B9A9BE6FD58F2A56" modified="2007-12-04" version="1">MIRSPLITVMVQAVRKAGRNLARDFGEVENLQVSLKGPANFVSSADRKAEETLYAELSRARPGYGFTMEERGKVEGQDEANEWVIDPLDGTTNFLHGIPLFAISVALVRNGVPFAGVIFNPVTDELYVAEKGQGAYLNDRRLRVAARRKLADCVVGCGIPHLGRGDHNKFQRELALVQGQVAGVRRTGAAALDLAWVAAGRFDAFWERDLSSWDMAAGMILIREAGGSVTDLDGHDKSLENGHIIAGNADMREDLFRLLKKA</sequence>
</entry>
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    <accession>A8IM68</accession>
    <name>A8IM68_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sel1-like repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0499</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0499"/>
    <dbReference type="EnsemblBacteria" id="BAF86497">
        <property type="protein sequence ID" value="BAF86497"/>
        <property type="gene ID" value="AZC_0499"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0499"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_36_1_5"/>
    <dbReference type="OMA" id="YYRRGCH"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723708" evidence="2">
        <location>
            <begin position="32"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="337" mass="35227" checksum="FE758F5EC55DAB16" modified="2007-12-04" version="1">MMDRVLRLLRPLLGIAAASALSVALALPAAAQDPKPAQKPAAKPAAKPAAPKAPVSSQPEDAAYGAYQRGLYLAAYKEASARAAAGPDAAAETLLGEIYAQGSGVPRSPAKAVEWYQKAIDHGSEQAAFSLAMMNLMGDGIPRDLKKAAQLLEVAAKKGNASAAYNLGLLYLQGEAMPQDFTLAAKWFRQAADAQVADAQYALSVLLRQGNGVPADKDAALKMLAAAAAQDHVTAQVEYAIAIFNGDGVPKDEAKAAALFKKAALAGNAIAQNRYARVLSAGRGAPQDKVRAAAWHMLSKAQGLGDPYLDDFVAKLTPEEQQKATALAHKWMGESRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IME3</accession>
    <name>A8IME3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD/NADP dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0536</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
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                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Akiba N."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Herder J.D."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0693"/>
    <dbReference type="EnsemblBacteria" id="BAF86691">
        <property type="protein sequence ID" value="BAF86691"/>
        <property type="gene ID" value="AZC_0693"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0693"/>
    <dbReference type="eggNOG" id="ENOG502ZA0U">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_277526_0_0_5"/>
    <dbReference type="OMA" id="QWHGRMP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1142" mass="123507" checksum="79523BDECBD3E66E" modified="2007-12-04" version="1">MAACGRGNMGKIRLWLSGFAWGAMLGVMASVVMGVAVFRPDIWEKLSYERIERALTRKTQSTLDTSAPPPASAPAASGAVLFANTRTAPALEQNYAPPHAFGPDDVLVIKGRNASNDFVEVDLRIDDSASKDWGSRFGGVKTVPPGPFEWVVPFKGLTDQNKRAMDINAITRIILFSPENLPAAQIASVTLERRPQPAAAAGSAPGAAPARANAALFTDASTSPALEQNYAPPRAFGPDDALVIKGSNPTGSAIEVDLRIDDSASKDWGSRFGMAKSVPPGPFEWVVPFKGLADQNKREMDIKAITRIILFSPENQPAAQIASASIENRPGAGDTTGSTGGAANEAKMGQSWLKGARTTAEQEFYPPMSFAQDQEVVVTGTNTDSKPITLYLRIDDVNSKNWNSRVNATVTVPPGPFTFRSPVSSWVTPSKARLDRTRVARFVISLGDGEGPIRLGDVHVAGGSPLPKDALGLRFGPADVSVPGFETVTRNDLRLSPAGRDLVRTQNDPLLSSGLNGVRTITVPWTKSDTATISLWTEDQGEWEYFPHSLHRTFIINGQVALKEDYRPDEWVEKVFHRGLWKEAMIDGDPWEVYASRRAGLVTATVPVIDGKITVQISSDQPPNDGYIAAMVIAPGASTAAAEAVEAWRRGRYMERWPVVDKPVDPKLAQGTTLRVLPYGTPRSQHPFWDPNLPTQTRLKALRGQMVSIDFLAFSDQSDANPDVALKLPEGITGEVRWGKWTYMRRGGGENSLSITSDVLEGDLTRLRIAAGIPRRMNVTFTVPETASGTLPVVLAMNIGGASVEARADVEVAPVTLPATATPVGYYMAAPNPDFWFPPKPATADRLMACDLKALRRFGLTGLSPDLVTPTADQRARYLEQTRLAKDAGFSPPFFDYVSVKLLADKVGVQAMGENIGATEAALTAAGLPLPLWSIADEPQNLQSPMMDLKRLRDAIRVYAPKAKIAGQLNDIKDKPFLPFFDTVLVNTGFGVSARDFADLKAQGITPWLYNMPDIEAAAGFLLWRVGAEGYIQWHARAATADPSDPTDGREPDFMFLPLTADRCQSVPTVDAMVVATGDGITDLRLLQWLDGRAASDPKAKALRDEIFAAIPGDWVGFEKQKPNLPALRRKLIDYAGATAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPX5</accession>
    <name>A8IPX5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0712</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169243.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0712"/>
    <dbReference type="EnsemblBacteria" id="BAF86710">
        <property type="protein sequence ID" value="BAF86710"/>
        <property type="gene ID" value="AZC_0712"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0712"/>
    <dbReference type="eggNOG" id="COG1208">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_2_1_5"/>
    <dbReference type="OMA" id="INHAHLG"/>
    <dbReference type="OrthoDB" id="1557977at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="233" mass="25522" checksum="E4ADE35AEE6F3F73" modified="2007-12-04" version="1">MVLAAGMGTRMRPLTDHRPKPLVEVDGRALIDHVLDRLEASDIREAVVNVHHHADQLEQHLALRTAPPRIHISDERGQLLETGGGIRKALHFFHGEPFLAINADTIWIEGVQPNLKRLMARFDPATMDALLLVAGAATSVGYDGAGDFLMDPNGVLDWRGERLVAPFVYAGACVLKPDLFEGTPEGGFSLTKVFAKSIEARRLYGLRLEGVWMHVGTPDAIPAAEEAIRRSSD</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-10-01" modified="2022-08-03" version="118" xmlns="http://uniprot.org/uniprot">
    <accession>Q04856</accession>
    <accession>A8IBK0</accession>
    <name>TRKA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Trk system potassium uptake protein TrkA</fullName>
            <shortName>K(+)-uptake protein TrkA</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">trkA</name>
        <name type="ordered locus">AZC_3082</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1991" name="Mol. Gen. Genet." volume="231" first="124" last="138">
            <title>Characterization of a novel Azorhizobium caulinodans ORS571 two-component regulatory system, NtrY/NtrX, involved in nitrogen fixation and metabolism.</title>
            <authorList>
                <person name="Pawlowski K."/>
                <person name="Klosse U."/>
                <person name="de Bruijn F.J."/>
            </authorList>
            <dbReference type="PubMed" id="1661370"/>
            <dbReference type="DOI" id="10.1007/BF00293830"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-111</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Part of a potassium transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The RCK N-terminal domain binds NAD and possibly other effectors. This is expected to cause a conformation change that regulates potassium transport.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="X63841">
        <property type="protein sequence ID" value="CAA45332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S18626">
        <property type="entry name" value="S18626"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171606.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q04856"/>
    <dbReference type="SMR" id="Q04856"/>
    <dbReference type="STRING" id="438753.AZC_3082"/>
    <dbReference type="EnsemblBacteria" id="BAF89080">
        <property type="protein sequence ID" value="BAF89080"/>
        <property type="gene ID" value="AZC_3082"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3082"/>
    <dbReference type="eggNOG" id="COG0569">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046525_0_2_5"/>
    <dbReference type="OMA" id="IACQVAY"/>
    <dbReference type="OrthoDB" id="1768241at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0406">Ion transport</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0520">NAD</keyword>
    <keyword id="KW-0630">Potassium</keyword>
    <keyword id="KW-0633">Potassium transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0677">Repeat</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000148711" description="Trk system potassium uptake protein TrkA">
        <location>
            <begin position="1"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal 1" evidence="3">
        <location>
            <begin position="2"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal 1" evidence="4">
        <location>
            <begin position="144"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal 2" evidence="3">
        <location>
            <begin position="235"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal 2" evidence="4">
        <location>
            <begin position="372"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="7"/>
            <end position="11"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <label>1</label>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <label>1</label>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="1">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <label>1</label>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <label>1</label>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="235"/>
            <end position="266"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="sequence conflict" description="In Ref. 2; CAA45332." evidence="5" ref="2">
        <original>KVARIRAQTYLQPEWRS</original>
        <variation>SPASAPRPICSPNGA</variation>
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="5"/>
    <sequence length="458" mass="49334" checksum="C8F21DF257FF28B4" modified="2008-02-26" version="2">MKVVICGAGQVGFGIAERLASEQNDVSIVDASPRRIQIATDQLDVRGVVGHGSHPDVLARAGIEQADMLIAVTLHDEVNMVACQVGHSLFNVPTKVARIRAQTYLQPEWRSMLSRDHMPIDVVISPEIEVGEMVLRRLSLPGAVDTVSFGDGSVVIAGVLCGEACPVVDTPLTQLTQLFPDLPATIVAINRNGKVMATRSSDQIQTGDIAYFVAPADQVGRTLSIFGHDEIPAKRIIIGGGGNIGLYVAQELEKRNAAARIKVVESNRERAQAIAEGLSRSVVLHGDSLAREILDEAGVADSDTMIALTNDDRVNILSCLLAKQLGAQRILALVNEQGYAGFAHGLGIDAYVNPRQITVSKVLQHVRRGRIRGVHSLLDGAGEMIEAEALETSPLVGRPLRDIDLLKGMRIGAVVRNGVVMRPSGDTVVRAQDRVVLFALADDIKRVEQLFRVSLEFF</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-10-01" modified="2022-05-25" version="115" xmlns="http://uniprot.org/uniprot">
    <accession>Q07757</accession>
    <accession>A8INZ6</accession>
    <name>NODJ_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Nodulation protein J</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="primary">nodJ</name>
        <name type="ordered locus">AZC_3812</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1993" name="Mol. Microbiol." volume="9" first="145" last="154">
            <title>Identification of nodSUIJ genes in Nod locus 1 of Azorhizobium caulinodans: evidence that nodS encodes a methyltransferase involved in Nod factor modification.</title>
            <authorList>
                <person name="Geelen D."/>
                <person name="Mergaert P."/>
                <person name="Geremia R.A."/>
                <person name="Goormachtig S."/>
                <person name="van Montagu M."/>
                <person name="Holsters M."/>
            </authorList>
            <dbReference type="PubMed" id="8412659"/>
            <dbReference type="DOI" id="10.1111/j.1365-2958.1993.tb01676.x"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
    </reference>
    <reference key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell inner membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="L18897">
        <property type="protein sequence ID" value="AAB51168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S35008">
        <property type="entry name" value="S35008"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="Q07757"/>
    <dbReference type="STRING" id="438753.AZC_3812"/>
    <dbReference type="TCDB" id="3.A.1.102.2">
        <property type="family name" value="the atp-binding cassette (abc) superfamily"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF89810">
        <property type="protein sequence ID" value="BAF89810"/>
        <property type="gene ID" value="AZC_3812"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3812"/>
    <dbReference type="eggNOG" id="COG0842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039483_3_1_5"/>
    <dbReference type="OMA" id="YSAFSRM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015772">
        <property type="term" value="P:oligosaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005981">
        <property type="entry name" value="ABC_transptNodJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01291">
        <property type="entry name" value="nodJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0997">Cell inner membrane</keyword>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-0536">Nodulation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <keyword id="KW-0813">Transport</keyword>
    <feature type="chain" id="PRO_0000182984" description="Nodulation protein J">
        <location>
            <begin position="1"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-2" evidence="3">
        <location>
            <begin position="25"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2"/>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="4"/>
    <sequence length="254" mass="27702" checksum="BBCBF5C848EF9465" modified="1994-10-01" version="1">MRERMVTWAAVFQRNAMSWRREMAASVLGSVIDPLIMLFGLGVGLGKIVDSVDGRSYAEFLACGLILTSAMSASNYEMLYGTYSRIYVTGTLKSMRYAPICVSDYLIGEVLWAAYEGVVAGTIVAVCTAFLGYIPGWSVIYILPDILFVALIFSSTSLLVAAISRGYALFAFYQSIAIAPLVFLSGVIVPRFTGNDVISGMIHFSPLYRAVNDVRNVVYEGRGTQVGPLLLLSLLYASVMVFISAKVICVRLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQC0</accession>
    <name>A8HQC0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1028</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1028"/>
    <dbReference type="EnsemblBacteria" id="BAF87026">
        <property type="protein sequence ID" value="BAF87026"/>
        <property type="gene ID" value="AZC_1028"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1028"/>
    <dbReference type="eggNOG" id="COG0697">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1030"/>
    <dbReference type="EnsemblBacteria" id="BAF87028">
        <property type="protein sequence ID" value="BAF87028"/>
        <property type="gene ID" value="AZC_1030"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1030"/>
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        <property type="entry name" value="MFS"/>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="469"/>
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        <location>
            <begin position="69"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="477" mass="49882" checksum="80ABB57A38BA389A" modified="2007-12-04" version="1">MQRAFWGARDPFSCVPGTAGAAGRAVQVWASLNAVRSVLHRGAVMTSLADAGAAAAPGQAAPAPLSLRLVLAGSIGNTLEWYDFGAYGFLAAIFARNFFPADSGFAALLAAYGMMAASFLMRPVGGVIFGHIGDRYGRRHALYLSAALMCVSTVAIGLLPTYATAGMAAPILLLALRLLQGVSIGGEYSSSVVFLAESAKPRWRGLLLSLCSMGAMGGTMLGSLVGAATASFLSQDELIAWGWRMPFFVGLLLGGTTLWLRHGLQSAPERSTEQPRSPLLQAFADDWRAIVICAVINLAGGVNTYTLFVYLVTYMEQVDGLSPGSALQVNTASMVVAVVLMPMFAALSDVIGRKRVLVASLLGFILFGWPLFRLVSGGTEEGAMLGQLGFAVLISAYTGVSPAVLAELFKRATRCSAAAVSNNVSRGIAGGTAPMVGVYLVSGLHDPMGPALYIICIALISLIATLCMTDRTRLPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="63" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifX/NifY family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169567.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="SMR" id="A8HQH1"/>
    <dbReference type="STRING" id="438753.AZC_1036"/>
    <dbReference type="EnsemblBacteria" id="BAF87034">
        <property type="protein sequence ID" value="BAF87034"/>
        <property type="gene ID" value="AZC_1036"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1036"/>
    <dbReference type="eggNOG" id="COG1433">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104194_3_0_5"/>
    <dbReference type="OMA" id="MQIGGPA"/>
    <dbReference type="OrthoDB" id="1995095at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051540">
        <property type="term" value="F:metal cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00853">
        <property type="entry name" value="NifX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003731">
        <property type="entry name" value="Di-Nase_FeMo-co_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036105">
        <property type="entry name" value="DiNase_FeMo-co_biosyn_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013480">
        <property type="entry name" value="NifX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034169">
        <property type="entry name" value="NifX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02579">
        <property type="entry name" value="Nitro_FeMo-Co"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53146">
        <property type="entry name" value="SSF53146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02663">
        <property type="entry name" value="nifX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitro_FeMo-Co" evidence="3">
        <location>
            <begin position="11"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="131" mass="14394" checksum="3B6267D7BBA9EF91" modified="2007-12-04" version="1">MKIAFATQDLKRVDAHFGWAKNIAIYEISPEGHHFVEAIQFDGDLKEDGNEDKLGPKIEAIKDCAILYVAAIGGSGAARVVANNIHPMKVNQPEEISDLLVKLEGVLKGAPPPWLRKALAKGQERSFDFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRA6</accession>
    <name>A8HRA6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1-like repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169685.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1154"/>
    <dbReference type="EnsemblBacteria" id="BAF87152">
        <property type="protein sequence ID" value="BAF87152"/>
        <property type="gene ID" value="AZC_1154"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1154"/>
    <dbReference type="eggNOG" id="COG0790">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000288_36_7_5"/>
    <dbReference type="OMA" id="WFQKSAN"/>
    <dbReference type="OrthoDB" id="1377603at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006597">
        <property type="entry name" value="Sel1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08238">
        <property type="entry name" value="Sel1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00671">
        <property type="entry name" value="SEL1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="265" mass="27763" checksum="AADEAB5885D2B1C5" modified="2007-12-04" version="1">MGLFDFLRRPAPCPPPSESVEARMGRALDAAASGDYEGALALWEPLAREGIARAQNNIGACFAEGLGVARDPEMAQKWLSLSAQSGDPVGQRNLAALYFKGEGVPQDYVHAAELYGAAAAQGDAPAQDMLSWMLLEGEVIPADVAEARRWAEAAAEQGVASSMTRMGMLYHNALGVERDAAEAARWWQKGAEGDDADGQAMLGAAYHIGSGVPRDPVAAYAWLLRAQAGGSQLAAPFMTSAREALSPDQQAEAERIAAAPLPGAG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="79" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRJ3</accession>
    <name>PDXH_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="1">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">PNP/PMP oxidase</fullName>
            <shortName evidence="1">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pdxH</name>
        <name type="ordered locus">AZC_1197</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="1">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <comment type="sequence caution" evidence="3">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAF87195" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87195.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172750.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4230"/>
    <dbReference type="EnsemblBacteria" id="BAF90228">
        <property type="protein sequence ID" value="BAF90228"/>
        <property type="gene ID" value="AZC_4230"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4230"/>
    <dbReference type="eggNOG" id="ENOG5032SSN">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_164851_0_0_5"/>
    <dbReference type="OMA" id="NIHSPHP"/>
    <dbReference type="OrthoDB" id="2053618at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="84" mass="9339" checksum="5775A9DCC62C97CE" modified="2007-12-04" version="1">MKKRHLATLELIFSHPVSGSVRWSDVVALFQALGAEVSEREGSRVGVVLFGEVRVFHRPHPSPNTDKGAVASIRKWLDEHGVRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTT1</accession>
    <name>A8HTT1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0869</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169400.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86867">
        <property type="protein sequence ID" value="BAF86867"/>
        <property type="gene ID" value="AZC_0869"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0869"/>
    <dbReference type="HOGENOM" id="CLU_2115949_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="114" mass="12151" checksum="776ADC1E3C4F2093" modified="2007-12-04" version="1">MTVFRRAKASTEAPPPAVPGRGHNAPPAEDARLSAFEDLESQICDLSLMAGIASALFEALFEDVAAHRELNGGRADCYLIDGGTLEKVSFAISNTLTRAADLRASFYEAHATAR</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-05-20" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTW6</accession>
    <name>EFTU_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Elongation factor Tu</fullName>
            <shortName evidence="2">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tuf1</name>
        <name type="ordered locus">AZC_0880</name>
    </gene>
    <gene>
        <name evidence="2" type="primary">tuf2</name>
        <name type="ordered locus">AZC_2556</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169411.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HTW6"/>
    <dbReference type="SMR" id="A8HTW6"/>
    <dbReference type="STRING" id="438753.AZC_0880"/>
    <dbReference type="EnsemblBacteria" id="BAF86878">
        <property type="protein sequence ID" value="BAF86878"/>
        <property type="gene ID" value="AZC_0880"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF88554">
        <property type="protein sequence ID" value="BAF88554"/>
        <property type="gene ID" value="AZC_2556"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0880"/>
    <dbReference type="KEGG" id="azc:AZC_2556"/>
    <dbReference type="eggNOG" id="COG0050">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_007265_0_1_5"/>
    <dbReference type="OMA" id="EGDKEWG"/>
    <dbReference type="OrthoDB" id="621774at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0251">Elongation factor</keyword>
    <keyword id="KW-0342">GTP-binding</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000337319" description="Elongation factor Tu">
        <location>
            <begin position="1"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="tr-type G">
        <location>
            <begin position="10"/>
            <end position="207"/>
        </location>
    </feature>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
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    </evidence>
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</entry>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Lee KB."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <begin position="56"/>
            <end position="76"/>
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        <location>
            <begin position="137"/>
            <end position="156"/>
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        <location>
            <begin position="176"/>
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    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="237"/>
            <end position="365"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="372" mass="40632" checksum="663C6ED2A63945CB" modified="2007-12-04" version="1">MALLISPGGGRGDMIVSRLDEYRRRICRVLVAMASLCVVGLWVFETETQVITELDRIAYPLLLAAFVVSLFLMLALPRWHRMAEWIAYLSFTTYCLVGVAAFGHLAEQTRLYTIANTLQWMPMLYVASFILLQRRDAVIAAALVFLSMSIPIVVEFSASDSYLKDRVLGSLVINAYLVHLVILVSLSLFVMTSLAFEQARAKAKALETMASTDSLTGTMNRRGLEQILRHVAGGSSGEIGLILIDIDNFKPINDTYGHLAGDAVLQAVAKRLAGVVRDSDVVGRWGGDEFLIITRDAQLTDVIAMADRARQHVGTHVLAGMRVTLSAGVGVWDGQGPWADALQRIDRALYSAKAEGRNRTAEAATAPNPIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV50</accession>
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        <recommendedName>
            <fullName evidence="5">YkuD domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="6" type="ordered locus">AZC_1011</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YkuD family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169542.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1011"/>
    <dbReference type="MEROPS" id="C82.003"/>
    <dbReference type="EnsemblBacteria" id="BAF87009">
        <property type="protein sequence ID" value="BAF87009"/>
        <property type="gene ID" value="AZC_1011"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1011"/>
    <dbReference type="eggNOG" id="COG1376">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042399_0_0_5"/>
    <dbReference type="OMA" id="DYATTEP"/>
    <dbReference type="OrthoDB" id="975147at2"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071972">
        <property type="term" value="F:peptidoglycan L,D-transpeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723084" description="YkuD domain-containing protein" evidence="4">
        <location>
            <begin position="27"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="YkuD" evidence="5">
        <location>
            <begin position="82"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="220" mass="24373" checksum="030BDD849A139C5D" modified="2007-12-04" version="1">MTRDLFPPPAALSRRALVLGTPLLLAACVTNSPPPVVQTLGDPRYGEVVGEPFEVPAVDTSGLDPRLLRQVVDYPSKYPVGTIVVDVPNRYLYLVEKDGKAIRYGVGVGKQGYSYRGWATIKRKEKWPHWTPTPNMIAKQPERYKPYAAGLPGGETNPLGPRALYLYDGDRDTMFRLHGTIEPDTIGTEVSSGCIRLLNQDIIDLYERVPLGTRVIVINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVH6</accession>
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        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
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            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
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        <name evidence="7" type="primary">mltG</name>
        <name evidence="9" type="ordered locus">AZC_4316</name>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172836.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4316"/>
    <dbReference type="EnsemblBacteria" id="BAF90314">
        <property type="protein sequence ID" value="BAF90314"/>
        <property type="gene ID" value="AZC_4316"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4316"/>
    <dbReference type="eggNOG" id="COG1559">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_025574_0_0_5"/>
    <dbReference type="OMA" id="IAMPGKA"/>
    <dbReference type="OrthoDB" id="708179at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="343"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="356"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="399" mass="42470" checksum="1062AE3C8BA95408" modified="2007-12-04" version="1">MEQPEQKPKKRRSRGANHPAVVVGSAVFTLLLFLTVGGGLVGWYGQRAYNEAGPLATEKNVVVPRGSGLRDIADLLEREGIIRNWMVFIAGHQFTHRGESLHAGEYAFKPGVTMADVVDTMVAGHVVQHQITVPEGLTSQQVVDRLNDNPLLTGTPRVPLEGTLLPETYAIVRGMTRQEVLKRMSADQQKLVADLWAKRAPDLPLKSPEELIILASIVEKETSKADERPRVAAVFINRLTKKMKLQSDPTIIYGIVGGKGTLGRPISRTDISTPTPYNTYAIDGLPPGPIGNPGKASLVAVANPAKTKDLYFVADGTGGHVFAETLEQHNRNVARWREIEAEMKAKAAAQPPAAATPTAAPSSGTSAPAPANGAGTPAPEAAPATPQRGTGTSAPKPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8HW75</accession>
    <name>A8HW75_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4399</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172919.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4399"/>
    <dbReference type="EnsemblBacteria" id="BAF90397">
        <property type="protein sequence ID" value="BAF90397"/>
        <property type="gene ID" value="AZC_4399"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4399"/>
    <dbReference type="eggNOG" id="COG1116">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="WKEYGDQ"/>
    <dbReference type="OrthoDB" id="1832232at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="272" mass="30167" checksum="2D77A4C749DC39EA" modified="2007-12-04" version="1">MTAISIRHLWKEYGDQIVLEDINLEFAPRSFIALVGPSGCGKTTFLRILLSEETATRGEVLIDGKPIAPEPGADRGVVFQRYSVFPHLTVLGNVLLAAELPRAPLTGRLFGSARRAAMEEARALIAEVGLAGAEDKYPAALSGGMQQRLALAQAIMRKPRILLLDEPFGALDPGIRADIHQLMKRLWNTCEMTVVMVTHDLREAFTLATRVIAFERRRNRPEERERFGATIARDIEVWPPRVAGQLDLFRPDRDDPVAVEGPGRDDPALMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWK4</accession>
    <name>A8HWK4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamine synthetase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4442</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glutamine synthetase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_4442"/>
    <dbReference type="EnsemblBacteria" id="BAF90440">
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    <dbReference type="eggNOG" id="COG0174">
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        <property type="term" value="F:glutamate-ammonia ligase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Gln_synth_cat_dom"/>
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        <property type="entry name" value="Gln_synth_gly_rich_site"/>
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        <property type="entry name" value="GLNA_ATP"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="5">
        <location>
            <begin position="133"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="470" mass="52054" checksum="0B11E73ABFCD26B2" modified="2007-12-04" version="1">MAKRTKTADTSDKAFLKSPRGVASLAEAKAWMAARGITEIECIVPDLAGVARGKIMPASKFLHSPVMNLPLSVFFQTISGEYPDYEGLVDSVVADSDLVLEPDFATLCSVPWAQDPTAQLVHDAYHRDGRPVEEAPRQVLKNVLDLYAKRGWKAVVAPEIEFYLVEPNTDPDYPLKPPVGRSGRPEIGRQSYSIQAVNEFDALFEDMYDYCEAQGLAIDTLIHEDGAAQMEINLLHGDPLTLADQVFLFKRTIREAALAHKIYATFMAKPIANEPGSAMHIHQSVVDAKTGRNIFSDEDGDPTPEFFSFIAGQQKYLPAVLCILAPYVNSYRRLTRDSMAPINVQWGYDNRTAGLRVPPSLPAARRVENRVPSSDANPYLVIAASLACGYLGISQGLRPTEPLEGDAKDKPFDLPRGLLEAVAEFAECEELAQVLGRRFVTTYAAVKQAEFETFMRVISPWEREYLLLNV</sequence>
</entry>
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    <accession>A8HXG3</accession>
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        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1498</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170026.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1498"/>
    <dbReference type="EnsemblBacteria" id="BAF87496">
        <property type="protein sequence ID" value="BAF87496"/>
        <property type="gene ID" value="AZC_1498"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1498"/>
    <dbReference type="eggNOG" id="COG1917">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="ESTYVME"/>
    <dbReference type="OrthoDB" id="1928636at2"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
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        <property type="entry name" value="RmlC-like_jellyroll"/>
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    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
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        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720754" evidence="1">
        <location>
            <begin position="26"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin_2" evidence="2">
        <location>
            <begin position="55"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="135" mass="14063" checksum="87AA65ACD406B076" modified="2007-12-04" version="1">MLSRRGFVSCAICAAVGMVASGADAVAQTPGVVRTVLQKTEFPGDKYVCILMTAEFDAGLKVARHTHPGVESTVLVAGGGTLSVKGQPDRVMAAGDGFQIPPEVPHAFQVGSEKVRLAITYIVEKDKPLSSPAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="51" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXV9</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1545</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="1 3">Belongs to the bacterial solute-binding protein 3 family.</text>
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        <property type="protein sequence ID" value="BAF87583.1"/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <text>coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX</text>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="266" mass="27611" checksum="AB3F619CAFCCAA68" modified="2007-12-04" version="1">MSGRLANKVAIVTGAGCVGPGWGNGRAAAVLFAREGASVFAVDKNRDSMEETLDRARAEGGTIAPYACDVTDSAAVADMVSACLSTFGRADILVNNVGGSAPGGPVELSEEQWDRQIDFNLKSVYLTCKHVLPVMEAQGGGAIVNTASTSGIRWTGAAQVGYASSKAGVIQFSRVVAVQYAKRNIRVNTVVPGQMHTPMVEARLAGQRAGGDVDVLLQSRLARIPLGFMGDGRDTAAAALFLASDEARFVTGTEIVVDGGMSARCD</sequence>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Suzuki S."/>
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                <person name="Binnewies T."/>
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                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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            <authorList>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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                <person name="Suzuki T."/>
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                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        </source>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </comment>
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        <property type="protein sequence ID" value="BAF87362.1"/>
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    <dbReference type="STRING" id="438753.AZC_1364"/>
    <dbReference type="EnsemblBacteria" id="BAF87362">
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    <feature type="coiled-coil region" evidence="2">
        <location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87362.1"/>
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    </evidence>
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        <source>
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    <sequence length="380" mass="39852" checksum="03A482248D3E9CE9" modified="2007-12-04" version="1">MLPMDDIMARTKGIPAAITLIWIASGLALAAPHPARAASEQPVPVQLATAETRDVPVFVTSPGTVTAYNSVTVRTRVDGELQHILFKEGQDVAEGQLLALIDPRTYEAALQSAKAQLQQHEATLSNARLNLTRDTELGKSDFVSVQTLDNERAKVAELEAQVASDQAAISRAATELSYTRIVSPLSGRAGLRLVDQGNIVHAGDAGGLVVINQIDPISVISTLPEQSLPAVVKAMRAGALQAQALSREDGRILATGTVSLIDNQIDPNSGTVKLKSDFANARDALWPGQFVDIKVRVDVLPHAVTIPASALQRGPQGLFVFAVGPDDRAQTAPVSAGQIADGTAVIETGLAPGQRVITGGQYRVRPGSLVTVSVSGEAGQ</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_4671"/>
    <dbReference type="EnsemblBacteria" id="BAF90669">
        <property type="protein sequence ID" value="BAF90669"/>
        <property type="gene ID" value="AZC_4671"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4671"/>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="187"/>
            <end position="206"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="182"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="450" mass="47651" checksum="526EDFC2B80CF078" modified="2007-12-04" version="1">MADYYPLLVRAISGLPQNTAEARKVVYDRARAALLKQLRSVDPPLPEGEIGRERLSLEEAIRRIEKEYVGDAPEAAPPAPPPSPAPRPPRPEAAPHAPLNPRRPASPDQPPEPVRAGASKPAFVRPAPGSVPEDETTVIRDAEPTGGAEPSGDAPADERRPRVGRATVRNRNGADAAPETGGKGKRIAIFAGISLVLLGGIGVAIWKHSAIAALFGERPQQQAAPSAPPATPDQPKSTDRVTQAGGAARPAQPAQAPRAPGQATTTRALLFEESPGNAQQIQQFEGTVTWKTETVSGGPGQPPDIGIRAEIQIPERKINVSFTLRRNLDQTLPASHTIEINFALPPDFPYGGVANVPVVRVKQTESAQGAPLAGLSVKVSSTSFLVGLSAAQVDKERNLQLLQTRPWIDIPIVYTNNKRAIIAFDKGAAGTQAFQDAFSAWGELYKGDGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="58" xmlns="http://uniprot.org/uniprot">
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        <name evidence="7" type="ordered locus">AZC_4689</name>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173208.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4689"/>
    <dbReference type="EnsemblBacteria" id="BAF90687">
        <property type="protein sequence ID" value="BAF90687"/>
        <property type="gene ID" value="AZC_4689"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4689"/>
    <dbReference type="eggNOG" id="COG2259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058421_8_1_5"/>
    <dbReference type="OMA" id="HDFWNQT"/>
    <dbReference type="OrthoDB" id="2084223at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="135" mass="14144" checksum="8652171B2DA9D621" modified="2007-12-04" version="1">MKFLDNLALLVGRILMASLFLPAGVGKAMNLAGFAGMLAGKGLPMPDVLAIAAATVEIGGSILLVIGVLPRLTAFVVGGFTLIAALTSHQFWDITDSAARMAQQNNFFKNIAIIGGLMFYFAAGPGQYALGRRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I295</accession>
    <name>A8I295_AZOC5</name>
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        <recommendedName>
            <fullName evidence="4 7">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3 7">5.1.3.13</ecNumber>
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        <alternativeName>
            <fullName evidence="7">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
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        <name evidence="8" type="ordered locus">AZC_1834</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3 7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170362.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1834"/>
    <dbReference type="EnsemblBacteria" id="BAF87832">
        <property type="protein sequence ID" value="BAF87832"/>
        <property type="gene ID" value="AZC_1834"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1834"/>
    <dbReference type="eggNOG" id="COG1898">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_090940_1_1_5"/>
    <dbReference type="OMA" id="YRIDRPH"/>
    <dbReference type="OrthoDB" id="1618609at2"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="6">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="185" mass="20305" checksum="DE269A6BB7DE89E8" modified="2007-12-04" version="1">MTSITRLDIPEVVLITPPRFADPRGYFSETYKKSALDAAGLNHVFIQDNESLSTVPGIIRGLHFQAPPFSQAKLVRVVSGAIYDVAVDIRKGSPTYGKWVGATLTAEKGEQILIPHGFAHAFCTLTPDVRVLYKVDGAYSKASEGGIIWNDPDLAIDWPVSNALVSEKDEILPRFKDLDSPFIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2G4</accession>
    <name>A8I2G4_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Binding-protein-dependent transport systems inner membrane component</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1870</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <begin position="95"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 7 family.</text>
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        <property type="protein sequence ID" value="BAF87894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="TRAP_DctP_sf"/>
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        <property type="match status" value="1"/>
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    <dbReference type="Pfam" id="PF03480">
        <property type="entry name" value="DctP"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="dctP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87894.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="361" mass="39294" checksum="F59E2B8AB6CE3321" modified="2007-12-04" version="1">MPTPAPNMARPGRTIMADHTKAASNTGLSRRTLLAGAAAAIPLVAIRTSPARAAEFSFKVATGQSLTQPINARLEQACARIQEASGGRMELKFFPASQLGSDTDLITQVRSGGIEFLNIAGSVISTVAAGAAITNVGFAFADYDHVWRGVDGAVGTYVRGQVEKAGLLIVSKAADNSFRQITSFSKPIRVPADLKGYRIRVPVSPIFTSLFTSLGANPTSINFNELYTALQTRLVDGQENGLVAIDSGKLYEVQKYVSETNHIWDPFWLMANRRAFSRLPADLQEIVTREFDRAAMEQRADVVRLNGVLKEQLQTRGLAFETADKPAFRKELSDNGFYKTWKDKFGTDAWKALETVTGDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3C7</accession>
    <name>A8I3C7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Voltage gated chloride channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2008</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170535.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2008"/>
    <dbReference type="EnsemblBacteria" id="BAF88006">
        <property type="protein sequence ID" value="BAF88006"/>
        <property type="gene ID" value="AZC_2008"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2008"/>
    <dbReference type="eggNOG" id="COG0038">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG0517">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015263_5_2_5"/>
    <dbReference type="OMA" id="GPLTMTF"/>
    <dbReference type="OrthoDB" id="1560952at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="514"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="589" mass="61184" checksum="E26B0F849B4178EE" modified="2007-12-04" version="1">MSAGVEATGTEAASTRGFAQRLRTLARGRETSLVVLAALIGVLAGLSVTLISRGAELLHSVLFGAARISSIPRLPLHVLLWPAIGGLIMGGVILALKRWRPHSIVDPIEANALHGGRMSLPDSIILSLQTMLANGFGASVGMEAGYTQSGSGLASVIGQWLRLRRMDLRILVGCGAAGGIAAAFQAPLTGAFYGFELIIGVYAIPAAAPVMTSALIAYLTARQLGAASTPIYVPEIGPLEPSAYLPFLLLGLIAGGVAIGIMRLVTLVERGFARSGLPLWLRPAVGGLGVGALAYVSPQVLSSGEGALRIQVGTGITSAVALILLLKVCASSLSLGSGFRGGLFFSSLFMGSLLGKLFAGLAGSVVPWLALDPVIAAVVGMSALAVGVVGGPFTMTFLTLEITGDLHIAGLVLTASIGCSLLVRETFGYSFSTWRLHLRGETIRSALDVGWLRALTVERMMRTDVSVFGAGADLAAFRAAFPLGSVKTVALQDGEGRYVGLVPVAVAHSDAHPPTERIEVLACNGDDILLADMNVKQAAAVFDRAQIDELVVVDHAEGRRIIGLLSEAFLLRRYADELDKARRGVAGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3D9</accession>
    <name>A8I3D9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligopeptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2012</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2012"/>
    <dbReference type="EnsemblBacteria" id="BAF88010">
        <property type="protein sequence ID" value="BAF88010"/>
        <property type="gene ID" value="AZC_2012"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2012"/>
    <dbReference type="eggNOG" id="COG0444">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_23_5"/>
    <dbReference type="OMA" id="QMTEVII"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="331" mass="35612" checksum="FC67382AB564F6D5" modified="2007-12-04" version="1">MTMALLEVENLQVHFRTPGGVNRAVNGVSFHVEEGETLAIVGESGCGKSVTSMSMLRLIPEPPGKIAGAVRFAGRDLLKLSDKEMRAIRGNEISMIFQEPMTSLNPVLTVGRQIGETLRLHQGLDATAAEAKAVEMLSLVGIPAPERRVKEYPHQLSGGMRQRVMIAIALACNPRLLIADEPTTALDVTIQAQILDLMRDLKSRVGAAIVLITHDLGVVAEVAERVMVMYAGRKVEEAPVRELFANPRHPYTRGLLGAVPKLGSSLQGETSRLAEIPGQVPSLTKPIQGCVFAGRCAIATDVCRTWAPALEWKAPRHAAACHYAPKEAAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3M9</accession>
    <name>A8I3M9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-dihydrouridine(20/20a) synthase</fullName>
            <ecNumber evidence="6">1.3.1.91</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">U20-specific dihydrouridine synthase</fullName>
            <shortName evidence="6">U20-specific Dus</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA-dihydrouridine synthase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">yjbN</name>
        <name evidence="6" type="synonym">dusA</name>
        <name evidence="10" type="ordered locus">AZC_1633</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NAD(+) = H(+) + NADH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53340"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20) in tRNA + NADP(+) = H(+) + NADPH + uridine(20) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53336"/>
            <dbReference type="Rhea" id="RHEA-COMP:13533"/>
            <dbReference type="Rhea" id="RHEA-COMP:13534"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.91"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NAD(+) = H(+) + NADH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53348"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>5,6-dihydrouridine(20a) in tRNA + NADP(+) = H(+) + NADPH + uridine(20a) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:53344"/>
            <dbReference type="Rhea" id="RHEA-COMP:13535"/>
            <dbReference type="Rhea" id="RHEA-COMP:13536"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the Dus family. DusA subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the dus family.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.91" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1633"/>
    <dbReference type="EnsemblBacteria" id="BAF87631">
        <property type="protein sequence ID" value="BAF87631"/>
        <property type="gene ID" value="AZC_1633"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1633"/>
    <dbReference type="eggNOG" id="COG0042">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013299_2_1_5"/>
    <dbReference type="OMA" id="LIYPYVD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102264">
        <property type="term" value="F:tRNA-dihydrouridine20 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02041">
        <property type="entry name" value="DusA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004653">
        <property type="entry name" value="DusA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42907">
        <property type="entry name" value="PTHR42907"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00742">
        <property type="entry name" value="yjbN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0288">FMN</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="5 6 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Dus" evidence="9">
        <location>
            <begin position="11"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6 8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
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    <sequence length="338" mass="36505" checksum="F2597E58A7BEB40B" modified="2007-12-04" version="1">MPTEQNFRFSIAPMMEWTDRHCRAFHRTLSRRAWLYTEMVTAPAIIHGDRARLLGYSQAEHPVVVQLGGSNPALLAEAARICADFGYDEINLNVGCPSDRVKGGNFGACLMRDPALVAECVAAMRAAVSIPVTVKCRIGVDDQDVEEALDALADAVLAAGCARLIVHARKAWLKGLSPKENREIPPLDYDRVHRLKARLPHVPIELNGGLVTLEDARAAGAGLDGVMLGRAAYQDPDLLLEVDAQVHGETPPHADAFEAIAAFEPYIAAHLEAGGRLHDITRHMLGLFGGRPGARTYRRTLATEALVPGAGLEVLRKAVAAIRRPLAKDDGTRTGTEG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <dbReference type="EMBL" id="BAF87638.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170244.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1716"/>
    <dbReference type="EnsemblBacteria" id="BAF87714">
        <property type="protein sequence ID" value="BAF87714"/>
        <property type="gene ID" value="AZC_1716"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1716"/>
    <dbReference type="eggNOG" id="COG0810">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1674333_0_0_5"/>
    <dbReference type="OrthoDB" id="1664469at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006260">
        <property type="entry name" value="TonB/TolA_C"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01352">
        <property type="entry name" value="tonB_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720857" evidence="4">
        <location>
            <begin position="26"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="157" mass="17289" checksum="E285CEE5F6784B84" modified="2007-12-04" version="1">MKLKRMALGAALSALALLPAVPVLAAADTQPQSRKDWMKAAWSLMATHRALPADIPDRAGRYEVVVALRVRRDGTVSTAELVRSSGLPSLDNSVLKMVLLSAPFPPLPPDMRENELLAMPVAFSFDQPEGQERSVIDAKSLFESRKLMDKRRAENRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5G7</accession>
    <name>A8I5G7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfonate ABC transporter periplasmic sulfonate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2277</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CmpA/NrtA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2277"/>
    <dbReference type="EnsemblBacteria" id="BAF88275">
        <property type="protein sequence ID" value="BAF88275"/>
        <property type="gene ID" value="AZC_2277"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2277"/>
    <dbReference type="eggNOG" id="COG0715">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_037398_3_1_5"/>
    <dbReference type="OMA" id="FTGDIWK"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="CDD" id="cd13553">
        <property type="entry name" value="PBP2_NrtA_CpmA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044527">
        <property type="entry name" value="NrtA/CpmA_ABC-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="401" mass="43408" checksum="DD414E22D6D80F3D" modified="2007-12-04" version="1">MNGGHMLTDDFFSRRDVMRLSALLTAAGAAPFLQAGSARAQEKDAPVRVGYLPITDATPLLVAHGKGFYEAEGLKAEKPVLFRSWSQIVEAFLSGQVNVVHLLSPITVWARYGSKAPAKVVAWNHTSGSGLSVGPDIQSVKDLGGKTVAIPFWYSIHNVVLQALLKENGLTPVSKKTGTPAANEVNLLIMAPSDMVPALAANQIAGYIVAEPFNAAAEVLKVGRVLRFTGDVWKDHACCVVFMQEKDLAERPEWSQKVVNAIVKAQAWTRANRGETAELLSKDNPNKYTPHSLEVLKRVLDPAAADESAYVASGAIRHPDWREKRIDFQPYPFPSYTEELVTRLKGTLVEGDRGFLDALDPAFAAKDLVDDRFVKAALASSGGLAAFGLPESFTRTEVVSA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-04-08" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5S8</accession>
    <name>ACYP_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Acylphosphatase</fullName>
            <ecNumber>3.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName>Acylphosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">acyP</name>
        <name type="ordered locus">AZC_2316</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction>
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acylphosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170843.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I5S8"/>
    <dbReference type="SMR" id="A8I5S8"/>
    <dbReference type="STRING" id="438753.AZC_2316"/>
    <dbReference type="EnsemblBacteria" id="BAF88314">
        <property type="protein sequence ID" value="BAF88314"/>
        <property type="gene ID" value="AZC_2316"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2316"/>
    <dbReference type="eggNOG" id="COG1254">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_141932_3_2_5"/>
    <dbReference type="OMA" id="VGFRWSM"/>
    <dbReference type="OrthoDB" id="2034659at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000326655" description="Acylphosphatase">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Acylphosphatase-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="93" mass="9774" checksum="9D0525B67BB054BF" modified="2007-12-04" version="1">MTHTLHLVIHGRVQGVGYRAWCADEAVSRGLSGFVRNRREGTVEAVISGPSEAVAAMLEACRSGPAHAHVERIEEALAEAPPAGTGFRVAATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5Z0</accession>
    <name>A8I5Z0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YCII domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YciI family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170867.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2340"/>
    <dbReference type="EnsemblBacteria" id="BAF88338">
        <property type="protein sequence ID" value="BAF88338"/>
        <property type="gene ID" value="AZC_2340"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2340"/>
    <dbReference type="eggNOG" id="COG2350">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_110355_3_1_5"/>
    <dbReference type="OMA" id="HQHVRQA"/>
    <dbReference type="OrthoDB" id="1780176at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005545">
        <property type="entry name" value="YCII"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03795">
        <property type="entry name" value="YCII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YCII" evidence="2">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="102" mass="11346" checksum="ACC969476319BA38" modified="2007-12-04" version="1">MPYMIETFDKPGTLDLRARERDAHLAFLDAHKHLLLACGAKLDDEGNASGGGLYVVALETRAEAEAFIAVDPFFTAGLFERVQITRWRKAYVDGVCYLPEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I664</accession>
    <name>A8I664_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum ABC transporter periplasmic binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_2368</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein ModA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170894.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2368"/>
    <dbReference type="EnsemblBacteria" id="BAF88366">
        <property type="protein sequence ID" value="BAF88366"/>
        <property type="gene ID" value="AZC_2368"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2368"/>
    <dbReference type="eggNOG" id="COG0725">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065520_3_0_5"/>
    <dbReference type="OMA" id="VCAPQVP"/>
    <dbReference type="OrthoDB" id="1506401at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005950">
        <property type="entry name" value="ModA"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004846">
        <property type="entry name" value="ModA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01256">
        <property type="entry name" value="modA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724238" evidence="4">
        <location>
            <begin position="39"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>molybdate</name>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004846-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="270" mass="28366" checksum="FE3A430C75C2C6BA" modified="2007-12-04" version="1">MSLVSFAVQRLATSRFARRTFLSLALSALALSAPAAHAQEAVTVFAAASMTNALQDIAKAYTAKTGVPVRFSFAASSELAKQVEAGAPANIFISADNRWMDYLEQRNLIVKDTRVPALGNTLVVVVPASKPTQITISPAFDFAALLGKDGKLVTGNVDSVPVGVYAKAALTKLGLWDKVKAQIAGADSVRAALAFVERGEAPAGIVYGTDAAIAKNVVIAGTFPSDSHEPITYPFALVKDHDTAAAKAFYAELLSPEAKAVYAKYGFTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8I697</accession>
    <name>A8I697_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">DUF374 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170907.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2381"/>
    <dbReference type="EnsemblBacteria" id="BAF88379">
        <property type="protein sequence ID" value="BAF88379"/>
        <property type="gene ID" value="AZC_2381"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2381"/>
    <dbReference type="eggNOG" id="COG2121">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_086327_1_1_5"/>
    <dbReference type="OMA" id="HGQMFLA"/>
    <dbReference type="OrthoDB" id="1756450at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007172">
        <property type="entry name" value="DUF374"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04028">
        <property type="entry name" value="DUF374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF374" evidence="1">
        <location>
            <begin position="66"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="245" mass="26418" checksum="6C9D6AE218E89780" modified="2007-12-04" version="1">MWRRIRTNRGVQVALGTTFAYYFKAVAHTTRFVVEPADIYARIEENLPLIMTFWHGQHFLTPFVMKPHHKAKVLISRHADAEINAIAAEKLGVGTIRGSGATSPRDFHRKGGVSATYALIDTLAEGINVAMTADVPKIARHVGKGVVVVARHSGRPIVPIAMATSNRITLKSWDKASLNLPFSRGAAVAAAPIWVPRDADDAAIEAARLLVQRRLEAATARAEALVGRGSAPALIDGRAPGEAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8I6W5</accession>
    <name>A8I6W5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2052</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DoxX family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170579.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2052"/>
    <dbReference type="EnsemblBacteria" id="BAF88050">
        <property type="protein sequence ID" value="BAF88050"/>
        <property type="gene ID" value="AZC_2052"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2052"/>
    <dbReference type="eggNOG" id="COG2259">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_058421_3_1_5"/>
    <dbReference type="OMA" id="YVIATIE"/>
    <dbReference type="OrthoDB" id="2025630at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="137" mass="14257" checksum="38734939FAB78210" modified="2007-12-04" version="1">MSDSRTAPYAALLLRLALGILFLAHAGLKIFVFTPAGTAAFFGSLGLPGWFAYVTICWEVLGAAALILGIFPRLVAVLMIPVLAGAIATVHGPAGFFFTNPKGGWEFLALWIAGLLALALIGDGAFALKSTPVGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8I701</accession>
    <name>A8I701_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-protein synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">luxE</name>
        <name evidence="2" type="ordered locus">AZC_2063</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="417" mass="43099" checksum="ECAC22F0675B3491" modified="2007-12-04" version="1">MHEPRSRLPDPPHDGTSPSRRSRRGLDWFVFCVADIQTGFGPFVAVFLTTQKWTQLDIGLVLTISGLVSLFGQIPFGALVDALGALRRTAMVALIAIGISAVLFAAWPIFPVVLASRVLHAAASSVLGLCLVSLSLGLVGAGGISARLGRNAAFASAGTGVAALTMGAVGYYVSNHAVFFLAAALVIPALHALFSIDGREIAPPAPPQPGEGRGWRTTLSGLRHLAANRPLLIFCGCVVTFHLANAAMLPLAASMLTLRSSEAATLMVAAAMVVPQFTVTLLSPFVGQGAQSWGRKPLLIVGFAALVLRGVCFALTSEPYILVAIQVLDGISAAVLGVLVPLTVADVARGPHFNLAQGTVGCAMGIGASISTVLSGYMADTWGSYTAFMGMAAVAMLGLGGVAMLMPETRDRTPEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA52</accession>
    <name>A8IA52_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulatory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_2465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170991.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2465"/>
    <dbReference type="EnsemblBacteria" id="BAF88463">
        <property type="protein sequence ID" value="BAF88463"/>
        <property type="gene ID" value="AZC_2465"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2465"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_6_4_5"/>
    <dbReference type="OMA" id="ADIGFMR"/>
    <dbReference type="OrthoDB" id="1439189at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="301" mass="33482" checksum="E4905F1CCA04B649" modified="2007-12-04" version="1">MRFDLRHIRSFIVLAETLHFGRAAERLNMTQPGMSRLIGELEREVGVPLFRRTTRTVELTEAGKAFLGECALAMDRLDRAVSIARRTAKGETGILRIAYMDFAINGRLPELLRSFSRMRPDIRLELSFIATLKQYEALLADRIDIGFLIGPVDQPGLASYTFDRDRYVVLLPTTHPLSNVRNLRLSDLAREPFVLGSGENWGAFRNQLFALCHRAGFVPDIVQEASSSEGIFGLVAAGAGISLYASCVRNLQRRGIVIREIEDTPDQLLTCAAWISPTQSPGVQVFVDFLSQVWGGQIASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB88</accession>
    <name>A8IB88_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_2627</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2627"/>
    <dbReference type="EnsemblBacteria" id="BAF88625">
        <property type="protein sequence ID" value="BAF88625"/>
        <property type="gene ID" value="AZC_2627"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2627"/>
    <dbReference type="eggNOG" id="COG0601">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036879_0_1_5"/>
    <dbReference type="OMA" id="PNGYAAD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
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    </evidence>
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            <dbReference type="PROSITE" id="PS50928"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88625.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="335" mass="35743" checksum="775BA2152B3734F4" modified="2007-12-04" version="1">MQRRRPARVAAADRKADPMLVYVLRRILYTVPIALGVSLVCFALIHLAPGDPLSAIIPEGASPETVAQVRAAYGFDRPLPVQYLKWLQHVVMGDFGNSIMTQRPVMAEVLPALANTLMLAAAAVLFGFAAGCLLGVVSGYLAGKPTDKAVTAVSITGVSIPHYWLGMVLMVIFAVELNLLPATGMGEGGSGAFGFGWDSLQYLILPALTLSVIPAGIIARSVRGTIAEVRKQDFMQTLHAKGLPGRRIFVHVVKNALPAVLAVMGLQLAQLLGGSILVETVFSWPGTGFLLNNAIFTRDLPVLQGTILVLAMFFVLINLAVDVVQTAVDPRIKRA</sequence>
</entry>
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    <accession>A8IBB2</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171161.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2637"/>
    <dbReference type="EnsemblBacteria" id="BAF88635">
        <property type="protein sequence ID" value="BAF88635"/>
        <property type="gene ID" value="AZC_2637"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2637"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="entry name" value="Ald_DH/histidinol_DH"/>
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        <property type="entry name" value="Ald_DH_C"/>
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        <property type="entry name" value="Ald_DH_CS_CYS"/>
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        <property type="entry name" value="Ald_DH_N"/>
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    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
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        <property type="entry name" value="Aldedh"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="2" id="KW-0630">Potassium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="7">
        <location>
            <begin position="13"/>
            <end position="476"/>
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        <location>
            <position position="250"/>
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        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
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    </evidence>
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            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88635.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="482" mass="51401" checksum="C43C9BA9B6CD5005" modified="2007-12-04" version="1">MSEIALNYIAGAWVSGASETKNINPSDTNDVVGLYTQGSRADAEQAIAAAAAAAPRWARSTPQERHDVLKKVGDEILARREELGRLLSREEGKTLPEGIGEAARAGQIFLFFAAEALRLAGEKLASVRPGLDVEITREALGVVGIIAPWNFPIAIPAWKIAPALAYGNAVVFKPADLVPGSAYALSEIISRAGLPAGVFNLVMGRGSVVGQAFLESPKVNAITFTGSVETGRKVAQACVLNDPMKKCQLEMGGKNPLVVLNDADLAVAAECAVNGAFFSTGQRCTASSRFIVQEGIHDAFVDAVTERLKALKVDNALEAGTHIGPVVDEKQLEQDLNYIEIGRSEGAKLHWGGERLNRATPGFYLQPAFFTETTNAMRIAREEIFGPVACTIRVKDYDEALAVANDTPFGLSSGIVTTSLKYASHFKRNSEAGMVMVNTPTAGVDYHVPFGGRKGSSYGAREQGRYAAEFYTTVKTAYTNAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBM3</accession>
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    <reference evidence="7 8" key="1">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <comment type="similarity">
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        <property type="protein sequence ID" value="BAF89136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <source>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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    <sequence length="212" mass="23355" checksum="AB1950C61D26F9E0" modified="2007-12-04" version="1">MRLLAGLLLLLATATGAFAAEDRPGAFDFYVLSLSWSPSYCATRDRPDGLQCGGPRPFAFVVHGLWPQYEKGYPQDCDRSAPRLPQRQIDGMLDLMPSPGLVIHEWRKHGTCSGLSATAYFDLVRSARAKVEIPPSYVNPTDYRMVSPAEVETAFIAANPGLEANMLSVDCDKTRLREVRICLSKSLTFRPCPEVDAKSCPAGRRLAVPPLR</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="42" xmlns="http://uniprot.org/uniprot">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S58 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="RefSeq" id="WP_012171474.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_2950"/>
    <dbReference type="MEROPS" id="P01.101"/>
    <dbReference type="EnsemblBacteria" id="BAF88948">
        <property type="protein sequence ID" value="BAF88948"/>
        <property type="gene ID" value="AZC_2950"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2950"/>
    <dbReference type="eggNOG" id="COG3191">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_044458_1_0_5"/>
    <dbReference type="OMA" id="PHFWAAP"/>
    <dbReference type="OrthoDB" id="2000083at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005321">
        <property type="entry name" value="Peptidase_S58_DmpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36512">
        <property type="entry name" value="PTHR36512"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Peptidase_S58"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="336" mass="33694" checksum="4A271F70FAC9EC95" modified="2007-12-04" version="1">MRNLLTDVPGLTVGHATDLKLGSGVTAILCHPPAVAAVDVRGGAPGTRETDLLDPAATVPHVDAIVLSGGSAYGLDAASGVTSWLAAHGRGYLVKDIRVPIVPSAILFDLLNGGDKHWGRHSPYRDLGYAAAEAAGEDFALGSVGAGTGATTARVKGGLGSASAIAPTGHRVGALVAVNALGCPLMGEGPHFRAAPFERNGEFGGLGLPVPLPADGGGIHLKGATPKTATTIAVVATDADLTSAQTRHFAVMAQDGLALSLYPVHTPLDGDCVFALATGQATLSDPIGDLLAIGTTAAAVLARAVARAVYEATALPFPGAQPAWRDLFPGAVRGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="98" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDL5</accession>
    <name>A8IDL5_AZOC5</name>
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        <recommendedName>
            <fullName evidence="9">Cytochrome c oxidase subunit 1</fullName>
            <ecNumber evidence="9">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_2959</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Energy metabolism; oxidative phosphorylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cell membrane</location>
            <topology evidence="2 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2959"/>
    <dbReference type="EnsemblBacteria" id="BAF88957">
        <property type="protein sequence ID" value="BAF88957"/>
        <property type="gene ID" value="AZC_2959"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2959"/>
    <dbReference type="eggNOG" id="COG0843">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011899_7_3_5"/>
    <dbReference type="OMA" id="PVDFQYH"/>
    <dbReference type="UniPathway" id="UPA00705"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006119">
        <property type="term" value="P:oxidative phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01663">
        <property type="entry name" value="Cyt_c_Oxidase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033944">
        <property type="entry name" value="Cyt_c_oxase_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014241">
        <property type="entry name" value="Cyt_c_oxidase_su1_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02891">
        <property type="entry name" value="CtaD_CoxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0349">Heme</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="431"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="504"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="11">
        <location>
            <begin position="55"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="568" mass="62385" checksum="49A8DA63B269F104" modified="2007-12-04" version="1">MAHRHPGAAPAARIRDQGRPRTPTAPFGIEDWTMATQAASYGAHDDHVPTGWRRWVFSTNNKDIGIMYLIFAIVAGIVGGALSIGIRLELMEPGLQYFKNPQTFNVFTTGHGLIMIFFMVMPALIGGFGNYFVPLMIGAPDTAFPRINNIAFWLLVPAFALAIMSLFVEGAAGSDGFGGGWTIYPPLSSKLGHPGPAMDLLIFSLHVAGASSILGAINLITTIFNMRAPGMTLHKMPLFAWAQLITAFLLLLSLPVLAGAITMLLTDRNFGTTFFDPAGGGDPILFQHLFWFFGHPEVYILILPGFGIISHIISTFSRKPVFGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSASTQSYFVAATMIIAVPTGVKIFSWIATMWGGSLQFRTPMLWSIGFIFLFTVGGVTGVVLSNAGIDRSLHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMIPEFWGKLHFWVTFIGVNMVFFPQHFLGLAGMPRRYADYPDAFAHWNYISSIGSYISGVAVIIFLIGTALAFVRKEKAGDNPWGAGATTLEWTLPSPPPYHHFEVLPRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDM3</accession>
    <name>A8IDM3_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">Probable multidrug resistance protein NorM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">matE</name>
        <name evidence="5" type="ordered locus">AZC_2963</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Multidrug efflux pump.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2963"/>
    <dbReference type="EnsemblBacteria" id="BAF88961">
        <property type="protein sequence ID" value="BAF88961"/>
        <property type="gene ID" value="AZC_2963"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2963"/>
    <dbReference type="eggNOG" id="COG0534">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012893_0_1_5"/>
    <dbReference type="OMA" id="GPIIGQN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="338"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="432"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="459" mass="47677" checksum="BB98A57F321504D4" modified="2007-12-04" version="1">MRHVAVMTGTGSVGLVAVFMVDLLNLFYISLLGEAELAAAIGYAGTVMFFVTSVTIGLMIAASATVSRALGAGRRREARQRATTAAVLMLATCLILTAVTLPLLHPLLRLLGATGHTAAIAERFLFMVTLSTPLLGLGMVASGVLRATGDASRSMWVTLGGGIVTALLDPLLILVLHLGVDGAAYASSASRLFMAIAGLYWCGKHHRLLTRPTRRMIAENFRPIASIAWPAILTNVATPVGNAYVTSALAPFGDEAVAAWAVIGRVIPVAFGPLFALTGAVGPIFGQNLGAGRYDRLRTTLRDSLLLILCYVLLVWLAMALGRGSIASGFGLTDAGRGIVEFFCLVSAGSFMFLGALFVSNAAFNNLGAPLFSTLFNWGRATLGTVPFAWAGGQLMGPNGVILGQSLGAVAFGLAGMVFAFRLIEKIGRSGAPAAPGRHPAPAEMPPLSSPQDAAAIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDQ3</accession>
    <name>A8IDQ3_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2976</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
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                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Ussery D.W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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            <end position="45"/>
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        <source>
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    </evidence>
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        <source>
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            <dbReference type="EMBL" id="BAF89479.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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</entry>
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        <lineage>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <source>
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        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF89495">
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        <location>
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        </location>
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    <feature type="chain" id="PRO_5002724440" evidence="1">
        <location>
            <begin position="33"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="22"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="137" mass="14784" checksum="F84D72AC050D6D55" modified="2007-12-04" version="1">MDQENRMPLSRRTFALASLSLPLAVAAAPAFAAAFQPYTPAAFAAATKAGGPVFVHVYAPWCLQCRAQEGILSRLVNDPKYAKATFLRVAYDEQKDVVAKLGVPRSTLIAYDGSKETGRMSWGVTEADVVKVLDSAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8IEJ7</accession>
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            <fullName evidence="3 15">Cytochrome b</fullName>
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    <organism evidence="19 20">
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    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="20" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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                <person name="Ussery D.W."/>
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                <person name="Gevers D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="19 20" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
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            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="19 20" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="14 15" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="14 15" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14 15" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3616"/>
    <dbReference type="EnsemblBacteria" id="BAF89614">
        <property type="protein sequence ID" value="BAF89614"/>
        <property type="gene ID" value="AZC_3616"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3616"/>
    <dbReference type="eggNOG" id="COG1104">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_0_0_5"/>
    <dbReference type="OMA" id="IIYGQSE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="13">
        <location>
            <begin position="19"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="BAF89614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="405" mass="41398" checksum="9CCD4E8F7828D946" modified="2007-12-04" version="1">MQAFPLHPRGSAVMAEARVHLDHNATSPLRPEARAALMAALDQGGNPSSVHADGRAARGRMEGARAGVAALCGAPARGVMFTSGATEANALALHPSWEIAGRPVTCDVLLMSAVEHPAVLRGHRFPDAAVELLPVDEAGRLDLDALSDRLAAHAAAGRRALVSLMAANNETGVIQPVAEAAELAKVHGGLMHCDAVQAAGRLPLDMTALGLDLLSLSAHKLGGPQGAGALVAASEDTRPLVPLLRGGGQERGRRGGTENVPAVAGFGAAAEAARLAQPQEAMRLAHLRDLLEQEIVAALPETEVVGGAAARVPNTSCIAFGGLKAETLVIALDLSHIAVSAGSACSSGKVGPSHVLSAMGFDAVRAGGAIRLSLGWSSTEQDVERAIAALRRVVPQVRSRSLRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFX9</accession>
    <name>A8IFX9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_3662</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172185.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3662"/>
    <dbReference type="EnsemblBacteria" id="BAF89660">
        <property type="protein sequence ID" value="BAF89660"/>
        <property type="gene ID" value="AZC_3662"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3662"/>
    <dbReference type="eggNOG" id="COG2146">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_055690_4_0_5"/>
    <dbReference type="OMA" id="RCPHAGL"/>
    <dbReference type="OrthoDB" id="1632945at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="36"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="142" mass="15385" checksum="1CE4E2B61E316639" modified="2007-12-04" version="1">MSELFAICSTYEIDDGGARGFVLARLDESGAAKPWPIIVTRKSNSFFGFENACPHQGKRLDTVPGEFLDEEGNFLTCGVHHAQFDLDSGQCFIGPCQGKALTPVTLVIDDGDVCLVDVPLAEEDGLDLEEPDTFPEVMITSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IG86</accession>
    <name>A8IG86_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0056</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168587.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0056"/>
    <dbReference type="EnsemblBacteria" id="BAF86054">
        <property type="protein sequence ID" value="BAF86054"/>
        <property type="gene ID" value="AZC_0056"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0056"/>
    <dbReference type="eggNOG" id="COG2124">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001570_5_1_5"/>
    <dbReference type="OMA" id="SDQRHPY"/>
    <dbReference type="OrthoDB" id="520970at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="468" mass="52798" checksum="622AAE3507CF41B1" modified="2007-12-04" version="1">MLQLLQKPAPILEERGPDWFAPARPRPHDKRLPPLDLILAAKRNLISLWHVNDYRPTHGDMRLFGRQVFLANSPETVKYVMATRHDNYERKSPQMRRALENLLGDGLFISDGETWRRRRPLVSDIVHKNRVPAFGLTMEAVTLSFVERWRARPAGEPFNALTEMAELTAEIISRAVFGNELGARAAHDVVDAFTRYQGLIDNFNIGYFLGANEGLPVFRGPRLRRSVAQLDRVIDKVVTDHLEGRGEHDSMLDLLVKRQQKSPDLGLDVSALRNEAATIFMAGHETTAGVLTWAWYLISNAPWVEEAVLAELDRVCGSRTPTVDDVAQLDWCRSVIEETLRLYPPVPILARQAKDADTIAGIDIDPAALVVVVPWLLHRSEGLWDQPERFRPERFLTDRPTPYTYIPFAIGPRICAGLAFGLTEAILCFAILIQQFRIRVLPGTKVEPVSRLTLRPAGGLPVTAERRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGM6</accession>
    <name>A8IGM6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_0109</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0109"/>
    <dbReference type="EnsemblBacteria" id="BAF86107">
        <property type="protein sequence ID" value="BAF86107"/>
        <property type="gene ID" value="AZC_0109"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0109"/>
    <dbReference type="eggNOG" id="COG1201">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_002025_0_1_5"/>
    <dbReference type="OMA" id="VVDEWHE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026362">
        <property type="entry name" value="DEXH_lig_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017170">
        <property type="entry name" value="Lhr-like_ATP-dep_RNA_helic_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045628">
        <property type="entry name" value="Lhr_WH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
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    </evidence>
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        <source>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="149" mass="16275" checksum="49982C018A35D651" modified="2007-12-04" version="1">MSVPRVYLDTNVFIAAFEMTGAHSDHAWWILKGIEAGTIIGVTSEITLAEVLVKPMERDDEALADAYEGMIAPAPYFETVSVGRDVLTTAARLRAGRHSLRLPDAIHVASAQIAQCSVFITQDERIALPDDLRRLGVTPFTLDDILGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGW3</accession>
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    <gene>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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    </dbReference>
    <dbReference type="eggNOG" id="COG1073">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_663748_0_0_5"/>
    <dbReference type="OMA" id="IPARNDW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="261"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="365" mass="41023" checksum="FC8D78952A48E900" modified="2007-12-04" version="1">MVREEIFASPTLRVVRGAGDRSGPVVVTFEPYADFPSLDRAGFGAAFFAQQGIEAFHVIPARNDWYQDADMPAALAAIRAAVGEGRRLATYGSSMGGYAAYRFSGRLRADVVLACSPQYSVDPARVPWEKRWKRAAEGLRFPFDAEPVRREARAYLFYDPRTADRRHARLIGREMPVCHVRLPHAGHPCLPLLREMGLLGPTVEAVVRGTFDPQALEAEVRQRSDRSPRYLMHKALALPRVLRGRRVRLLDRALALAPDDPWVSLTYGWVLASHRDWDKADARFRKALALSPDDPSLLYVYRRFLERAGRHAEALAVQEAIVRRFPEAIVHVAELDRVRAQQARKGLLKRLIAALPGRGSHTARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="99" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH01</accession>
    <name>A8IH01_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <shortName evidence="9">HTPA reductase</shortName>
            <ecNumber evidence="9">1.17.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapB</name>
        <name evidence="12" type="ordered locus">AZC_0157</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:35323"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:35331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="EC" id="1.17.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0157"/>
    <dbReference type="EnsemblBacteria" id="BAF86155">
        <property type="protein sequence ID" value="BAF86155"/>
        <property type="gene ID" value="AZC_0157"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0157"/>
    <dbReference type="eggNOG" id="COG0289">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047479_2_2_5"/>
    <dbReference type="OMA" id="HHPNKAD"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016726">
        <property type="term" value="F:oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00102">
        <property type="entry name" value="DapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="10">
        <location>
            <begin position="31"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="11">
        <location>
            <begin position="156"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="(S)-2,3,4,5-tetrahydrodipicolinate binding" evidence="9">
        <location>
            <begin position="193"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="36"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="126"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="150"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>(S)-2,3,4,5-tetrahydrodipicolinate</name>
            <dbReference type="ChEBI" id="CHEBI:16845"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF86155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="296" mass="30611" checksum="CA68ACBF91B3D827" modified="2007-12-04" version="1">MRAGHLPRLTRRPSDRARIRFRERSDVSDLRVVINGAGGRMGQELLRAVLNGEGLSLAGALEHSTSGHLGEDAGVLAGLKPAGVTIESDAAATLNGTDVVIDFSTPASSVRLAERLAEAGIAIVIGTTGFSAAENAAIEAAARRTVVVKSGNMSLGVNMLAALTRQAAAALGIEFDIEIVEMHHARKVDAPSGTALLLGEAAAEGRGIHLPDWTAKARDGVTGPRRPGDIGFASLRGGSVVGEHAVIFAGPSERVELVHKAESRTIFANGALTAARWAKGREPGLYSMVDVLGLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHD8</accession>
    <name>A8IHD8_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3262</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3262"/>
    <dbReference type="EnsemblBacteria" id="BAF89260">
        <property type="protein sequence ID" value="BAF89260"/>
        <property type="gene ID" value="AZC_3262"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3262"/>
    <dbReference type="eggNOG" id="COG2801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027402_31_0_5"/>
    <dbReference type="OMA" id="NYTRECL"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="102"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="277" mass="31588" checksum="A4F4C29BF52CED4C" modified="2007-12-04" version="1">MAKLGVSERLACRVLGQHRSTQRKVPVGRADEAGLTADIIELATRYGRYGYRRITALLQASGWVVNVKRVERIWRREGLKVPSKQPKKGRLWFNGGSCLRLRPEHPNHVWSYNFVEDRTHNGRKFRMLNVIDEFTRECLAIRIDRKLNSTAVIDVLTDLFVLRGVPSHIRSDNGPEFIAKAVRDWITAVGARTAFIAPGSPWENGYCESFNSKLRDELLDGEIFYSLAEARIVIEDWRRHYNTERPHSALGYKPPAPAVIVPQVPPTSNAPNRPTMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHP2</accession>
    <name>A8IHP2_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">Alpha-E domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171826.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3303"/>
    <dbReference type="EnsemblBacteria" id="BAF89301">
        <property type="protein sequence ID" value="BAF89301"/>
        <property type="gene ID" value="AZC_3303"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3303"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_013951_0_0_5"/>
    <dbReference type="OMA" id="YNVYADP"/>
    <dbReference type="OrthoDB" id="517836at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025841">
        <property type="entry name" value="CP_ATPgrasp_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007296">
        <property type="entry name" value="DUF403"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04168">
        <property type="entry name" value="Alpha-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14403">
        <property type="entry name" value="CP_ATPgrasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-E" evidence="1">
        <location>
            <begin position="535"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF89301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="846" mass="92427" checksum="EA006FC540F9A867" modified="2007-12-04" version="1">MERGTRKGRRDGVSGAETRSIDFEQAAVESVLGGYETLPGVRDEMMDADGQPRPHWVAFLAELAELGPDGIRRRFSAADRYLRESGVFYRVYDDAGGNERPWSLSHIPLLLEKSDWQVLAEGLIERAELLEALLADLYGPGALVAGGALPAAAVAGSPEFLRPLVGVAPRGGRYLRFYAADVGRGPDGRWWVLSDRTQAPSGVGYALENRLAVTRALPDVSRTLRMERLASFFQNFRASLLKLDTTGEGRVGLLTPGSLNETYFEHALLARYLGFLLVEGEDLTVRGDAVNVRTVAGLKRIDVLLRRLDADFGDPLELNAHSRLGVPGLVHAVRQGGVALANALGSGLVEAPALMAFLPTLALQVLGRPLALPHVATWWCGQAAERAEVCEHLDDLVLTSAFGNAIPGLPRRFSAVGADLTAAERKRIETIMALRGGDLVAQDIARISTMPVWSGDKLVPRPFTLRVFLAATDDGWVVMPGGFCRISESRDARAFSMQRGDRSADVWVLSTEEVSSATLMPSPENVRIRRSSGTLPSRAADNLFWLGRYLERAEASLRLVRALVGRLSEVESSSGPLVMRLVSLLATWGAVPRDLARGTPARYGLAALTRNDLPGSLPQLVRSARASASVIRDRFSPDGWRALLDLEACIEAPLTGNVSEADAYERADAALRIIAAFSGLASENMNRLAGWRFLEIGRRIERSIALLRFARTFAEPAAPRGALNVLLQLADSQITYRTRYVMLEARGPVLDLVLLDPDNPRSLMFQIQRIADHLRVLPGRDPDLPPSLAERLVGRILSDLIAHTAETFELKHFDAMEADMLKLSDEIGAHYFIQGPEEAVYWPVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHR0</accession>
    <name>A8IHR0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171833.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF89308">
        <property type="protein sequence ID" value="BAF89308"/>
        <property type="gene ID" value="AZC_3310"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3310"/>
    <dbReference type="HOGENOM" id="CLU_205013_0_0_5"/>
    <dbReference type="OMA" id="MEMIDLF"/>
    <dbReference type="OrthoDB" id="2005742at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="59" mass="6555" checksum="B1885D414346FC0E" modified="2007-12-04" version="1">MEMIDLFPIVFGTFKVVVLGVCMYFAIKWHHDQAKLKKKAAEEQQAAAGAPAHPTETPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIQ1</accession>
    <name>A8IIQ1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative metal-sulfur cluster biosynthetic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3435"/>
    <dbReference type="EnsemblBacteria" id="BAF89433">
        <property type="protein sequence ID" value="BAF89433"/>
        <property type="gene ID" value="AZC_3435"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3435"/>
    <dbReference type="eggNOG" id="COG2151">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_091588_1_2_5"/>
    <dbReference type="OMA" id="LRMIIDP"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
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    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="2">
        <location>
            <begin position="39"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="134" mass="14794" checksum="5F3B4DDBE86B9ECE" modified="2007-12-04" version="1">MTMSDDFMTDEPMMPGTETEDLSSETATAVDWDEEAITAEIIEALRTVHDPEIPVNIYDLGLVYRIQLLPTVGAEIDMTLTAPGCPVAGELVSMVQRAVLTVRQIDVAKVNLVFDPPWDTNRMTDDVKLELGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIS9</accession>
    <name>A8IIS9_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Ferric uptake regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
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        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
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            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
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            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
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        <cofactor evidence="8">
            <name>Mn(2+)</name>
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        <cofactor evidence="8">
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        <text evidence="8">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
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    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
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        </cofactor>
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    <comment type="subunit">
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    <comment type="similarity">
        <text evidence="1 8">Belongs to the transketolase family.</text>
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    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="SMART" id="SM00861">
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    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
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    <dbReference type="SUPFAM" id="SSF52922">
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    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
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    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
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    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="45"/>
            <end position="65"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
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            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
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            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="694" mass="73840" checksum="B16A23D79B2D607D" modified="2007-12-04" version="1">MARWYQCRREVNPPPDRSLKWRAARRRPLFMSSRELHNRLANAIRFLAIDAVEAANSGHPGLPMGAADMATVLFTEKLKFDATAPKWPDRDRFILSAGHGSMLLYGLLHLLGYDAVSMDEIRRFRQLGSLTPGHPENFVTPGIETTTGPLGQGISTAVGFAMAERLMAARFGSEIVDHRTVVIASDGDLMEGISQEAIDIAGHLKLAKLTVLWDDNRISIDGPTSISVSTDQQARFAASGWNTLAVDGHDPVALLAALNTAYASEKPTLIACRTTIGFGSPAKAGSEKVHGSPLGAAEIEATRKALGWEAGPFEIPADALDAWRAAGRKGAEARAAWQARFDALPEATRAEFNRRMAGELPVAALKEAIAAVKAKAVADGGAVATRKSSEIVLDTLTKAVPEMLGGSADLTGSNNTRAKGQKSVTPTDFSGDFVHWGVREHGMAAAMNGIALHGGFIPYSGTFLAFADYSRPAIRLAALMGERVIHVLTHDSIGLGEDGPTHQPVEHLAALRAIPNTLVLRPADTVETAECWQIALEAKDRPSCLILSRQNLPLLRKDADGENKSAGGAYELLAASGEAQVSLFATGSELSLAVEARALLESEGVPTRVVSVPSFELFLARPLAERRAVIGKAPAKVGIEAAIRMGWDSIIGSDAAFVGMTSFGASAPAKELYKHFGITPQAVVAAALEQLRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMF4</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        <name evidence="2" type="ordered locus">AZC_0542</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0542"/>
    <dbReference type="EnsemblBacteria" id="BAF86540">
        <property type="protein sequence ID" value="BAF86540"/>
        <property type="gene ID" value="AZC_0542"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0542"/>
    <dbReference type="HOGENOM" id="CLU_1745939_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="149" mass="15898" checksum="34AED8F4FE234DAA" modified="2007-12-04" version="1">MRLRKALRRRMGKTGSPSPSRPNRERHMPARTRKELQDLKAELAATGAETAAAPKPRRHRAAAHPHAPEAPPPDVEAPSPEAPAAAAGEAAAEAEPETATFDQLHALVRDLQEALHEATEKAEDAVTSHPAAALASAFLLGLLVGRAWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMF8</accession>
    <name>A8IMF8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0544</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <location>
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        <ligand>
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        <source>
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    </evidence>
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        <source>
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    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
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            <dbReference type="EMBL" id="BAF89689.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
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    <sequence length="376" mass="39608" checksum="51299AA211E65DB1" modified="2007-12-04" version="1">MNAPLSIAPQPAGAAGAQAPVTDAPVPHAPAVIRFERIEKTYPARAASGAVAALQDVNLTVPEGAIVGVIGRSGAGKSTLIRLVNGLERATSGRLIVDGTEITALDEGGLRAARRSIGMIFQHFNLLARRTAFGNVALPLEIAGVPSREIKARVEPLLDLVGLGDKRDRYPAELSGGQKQRVGIARALAMRPRVLLSDEATSALDPETTNQILALLRKVNAELNLTVLLITHEMAVIKSVADRVAVLDGGRIVEEGRTFEIFARPRHPTTRSFLSALTGATLPAYFVDRLKPDYTPGAEAVLRIVFTGAHATDPVLSRVARDLGIDINIIQAQVDDIAGEPFGVIVVSVPGDPQTLSGVVATVEGLGHATEVVGYV</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF89727">
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    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3729"/>
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        <property type="entry name" value="DUF1501"/>
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        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="409" mass="44194" checksum="2A4BC8D40DEB2ACF" modified="2007-12-04" version="1">MIARSGDRPMGTMRDLNRRHVLAGLAGLAPMTVAGRVWAAPKADARLLVVFLRGAYDAANVVIPVSSSFYYESRPNLAIARPGSGVGSALSLDVDWGLHPALASSILPLFQRGEVAFVPFAGTDDLTRSHFETQDTIELGQEVNVRRDYRSGFMARLAHELTGVRPISFTEQLPLTFQGEVAVPNVAINAVGKAGIDSRQAKLITAMYEHGPLSGAVAEGFRVRDEVYQQVTDHMMEASRNAASPKGFELSARRIGRLMRETFNLGFVDVGGWDTHVNQGGATGYLADRLGELGRGLAGFAEEIGPKWNDTVVVVLSEFGRTFRENGNHGTDHGHGSVYWVLGGGVRGGRIAGEQVAVDQPHLFQNRDYPVLTDYRGLLGGLIRQLYGLDAASLGRVFANVTPKDLALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="41" xmlns="http://uniprot.org/uniprot">
    <accession>A8INS9</accession>
    <name>A8INS9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3785</name>
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    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <source>
            <dbReference type="EMBL" id="BAF86758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1026"/>
    <dbReference type="EnsemblBacteria" id="BAF87024">
        <property type="protein sequence ID" value="BAF87024"/>
        <property type="gene ID" value="AZC_1026"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1026"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_107_26_5"/>
    <dbReference type="OMA" id="SHRIFCK"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004888">
        <property type="term" value="F:transmembrane signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="Chemotax_Me-accpt_rcpt"/>
    </dbReference>
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        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00260">
        <property type="entry name" value="CHEMTRNSDUCR"/>
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    <dbReference type="SMART" id="SM00283">
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    </dbReference>
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        <property type="entry name" value="sensory_box"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
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        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0807">Transducer</keyword>
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        <location>
            <begin position="21"/>
            <end position="63"/>
        </location>
    </feature>
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        <location>
            <begin position="80"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="143"/>
            <end position="185"/>
        </location>
    </feature>
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        <location>
            <begin position="202"/>
            <end position="254"/>
        </location>
    </feature>
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        <location>
            <begin position="254"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="406"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        </source>
    </evidence>
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        <source>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF87024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="490" mass="52676" checksum="730355EDBD2DBDE3" modified="2007-12-04" version="1">MHMFSSQADAKLAAIQKSQAIIEFEPDGTIISANPNFLSAMGYTLAEIRGKHHSLFMPPEERDTTDYRQFWEDLRAGKFQRSEFRRLAKGGREIWIQASYNPVISSGGEVRRIIKVATDITGQKTHNADLQGQIDAINRVQAVIQFDLDGTILDANENFLKTMGYTLAEVQRRPHAIFMDPQEREAPSYRAFWDSLRAGTFQQAEFRRLAKGGREVWIQASYNPIFDASGRVYKVVKYATDITAQVQERMRRERRRCIDKELSEIAEAITAANHQAAAAASASTQASSGVQSVAAGAEELVASIHEIGSQVSRALDVASNAVGQAVRTKEIVSGLASVAQKIGAVVELINSIAGQTNLLALNATIEAARAGESGKGFAVVASEVKNLASQTARATEEITGQIIAVQASTSDAVGAIAGITETISEINDISSGIAAAVQQQSAVTSEISRSMHAAAGGVGEITRNLTSLSSATAQIDAANRKVLEAQREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQL3</accession>
    <name>A8HQL3_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">FeS assembly SufB protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB</name>
        <name evidence="3" type="ordered locus">AZC_1044</name>
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    <organism evidence="3 4">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1044"/>
    <dbReference type="EnsemblBacteria" id="BAF87042">
        <property type="protein sequence ID" value="BAF87042"/>
        <property type="gene ID" value="AZC_1044"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1044"/>
    <dbReference type="eggNOG" id="COG0719">
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    <dbReference type="OrthoDB" id="635721at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
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    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF101960"/>
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        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="153"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87042.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="493" mass="55068" checksum="2F9CFDFE15A9540C" modified="2007-12-04" version="1">MAAVQETIDQVRQIDVEQYKYGFVTDVESEKAPKGLSEDVIRFISAKKNEPEWMLEWRLDAYRRWLTMREPEWAKVNFPKIDFQDLYYYAAPKKKKALSSLDEVDPEILKTYEKLGIPLREQELLAGVERPEGERKIAVDAVFDSVSVATTFQKELKEAGVIFMPISEALKEHPELVRKYLGTVVPVTDNYYATLNSAVFSDGSFVYVPEGVRCPMELSTYFRINEKNTGQFERTLIIADKGAYVSYLEGCTAPQRDENQLHAAVVELVVLDDAEIKYSTVQNWYPGDKDGKGGIYNFVTKRGDCRGANSKISWTQVETGSAITWKYPSCVLRGDGSQGEFYSIAISNGHQQVDSGTKMIHLGKNTSSRIVSKGISAGQSQNTYRGLVSAHRKAKGARNFTACDSLLIGDQCGAHTVPYIEAKNPTTVFEHEATTSKISEDVLFYCVQRGLSQEEAVGLVVNGFVKEVLQQLPMEFAVEAQKLISISLEGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="73" xmlns="http://uniprot.org/uniprot">
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    <name>A8HQR2_AZOC5</name>
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            <fullName evidence="7">Phosphonate uptake transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_1055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1055"/>
    <dbReference type="EnsemblBacteria" id="BAF87053">
        <property type="protein sequence ID" value="BAF87053"/>
        <property type="gene ID" value="AZC_1055"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1055"/>
    <dbReference type="eggNOG" id="COG3639">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_064254_0_2_5"/>
    <dbReference type="OMA" id="RFAIIGR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005769">
        <property type="entry name" value="PhnE/PtxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01097">
        <property type="entry name" value="PhnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="93"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="291" mass="31225" checksum="4B067AF9BBA5B19F" modified="2007-12-04" version="1">MTATSPTAPRPVLETDVAAMRARYPDAFRAHPARRLKTAAFIGIIVGIALFALWALDFSPQRIWQGLSRLGLFFSLLFPPDAHGRLPAFMKALGETLAIAFLGTLTAALVAFPVAFLAAKNVVPNIFVHFSLRRVFDVSRSVDTLIWALMWINVVGLGPFAGALAIACADFGAFGKLFSEAIEAADRKPVEGVLASGGSGLHRVRFALVPQILPVIASQILYFFESNTRSATIIGIVGAGGIGGYLTELIRTLEMSQVCVIIIMILITVAVIDFVSSRLRFAIIGRKPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQV8</accession>
    <name>A8HQV8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 inner membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1068</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell inner membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169599.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87066">
        <property type="protein sequence ID" value="BAF87066"/>
        <property type="gene ID" value="AZC_1068"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1068"/>
    <dbReference type="eggNOG" id="COG2095">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_079909_0_0_5"/>
    <dbReference type="OMA" id="MMAIVML"/>
    <dbReference type="OrthoDB" id="1323133at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="209" mass="22197" checksum="B17880534C13E5C4" modified="2007-12-04" version="1">MLEDYDLFITQFVTLYALLEPIGHLSLFLALTGEHSKADRLRLAILSPLFAFAVLSFFALAGQTLLNAMNVSILSFQIAGGIILFSFSLSMIFGEAKKPSGVPEEKNLISQAIYPLATPTIAGPGAILSVVLLADNNRGSLIAQSMTVLAVASMMLLLMGAFLAGDIITRLIGSGGTNLVRRVMGILIAALSVDLVLSALAKWLHLPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="52" xmlns="http://uniprot.org/uniprot">
    <accession>A8HR10</accession>
    <name>A8HR10_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1092</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169623.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1092"/>
    <dbReference type="EnsemblBacteria" id="BAF87090">
        <property type="protein sequence ID" value="BAF87090"/>
        <property type="gene ID" value="AZC_1092"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1092"/>
    <dbReference type="eggNOG" id="ENOG5032Z7R">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_128167_0_0_5"/>
    <dbReference type="OMA" id="MCSEKPE"/>
    <dbReference type="OrthoDB" id="1841771at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035220">
        <property type="entry name" value="DUF5330"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17264">
        <property type="entry name" value="DUF5330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="140" mass="14712" checksum="1A47D8566BC9A774" modified="2007-12-04" version="1">MFFLLRMAFWLALILLILPIGVTSDGGRQIGAWQAFTAVQAAINDARGFCQRQPDACAVGGEMLDHMAEKAQASAKWVYDAIGAHKADAGTAPAAPQPSAAKEGSASHDLTPQDLAPAWSLEPQRGAPAPGMPLPPRRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HR11</accession>
    <name>A8HR11_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1093</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1093"/>
    <dbReference type="EnsemblBacteria" id="BAF87091">
        <property type="protein sequence ID" value="BAF87091"/>
        <property type="gene ID" value="AZC_1093"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1093"/>
    <dbReference type="eggNOG" id="COG2205">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_89_22_5"/>
    <dbReference type="OMA" id="FAYLRMD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="307"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="553" mass="58823" checksum="0198586EEAE73C7F" modified="2007-12-04" version="1">MKVAKPGARGSGGDPFATASFQDIVNADRVRDGAARLAFLKAFRVRLSPIVMQGRRGRRSHGGHMDWVLSDQRQGAGSLNAQPDAARSGRVRTSLRDLAGVGRHSAAALGALAFMCALAGGGLLLAAALGLSETGLPEGGWLLGCGLISAALSAVAAGLSLAAERLDRSMMGVDLALVTLHGRGGEVLGLEHADAARAHVPEDAWLGQGLFDRVLVPDRPAFLAALSTAAHGLSATESVCEVRLRCEGEGEAPDFVWMELRCVPAGEDRARAHWRDIHAVKIQLEEDHRARTEAERANLAKSRFLAAMSHELRTPLNTILGFSELLATDTEQRIDARRKEDYARIIHESGQHLLGVVNDILDLSRVEAGAYELSFEHIDMAHLVDGCVEMVGLDAARRNIKVTTLLPARLPRPMADQRAVRQMTLNLLSNAVKFSEHGGLVEVNVSAQNGVVSLSVRDSGAGMSPAEVERLGEPFFQAGDAERRARGSGLGLAVVRALVKLHDGAFEVTSSVGGGTTVTISLPVRRSSGVVSPFARAITDEAGRKDNEGRRIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRB7</accession>
    <name>A8HRB7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative thiol-disulfide isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1161"/>
    <dbReference type="EnsemblBacteria" id="BAF87159">
        <property type="protein sequence ID" value="BAF87159"/>
        <property type="gene ID" value="AZC_1161"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1161"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_11_0_5"/>
    <dbReference type="OMA" id="TIRYVRI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
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    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
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    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
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        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="67"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="229" mass="24311" checksum="16B43B016C065943" modified="2007-12-04" version="1">MNRMAAPEARGNRHTSDIVRTASAGPPMRDLTRRTVLCAGVAGVLLPALPVPLRAASEPPGQAILERTAAETLPSFTLPELGGRDVALSAQAGRVVLVHFFATWCEPCREELPALSRLATDHPQDVTILAVDVGEVDLRVRRFFEGLPVPFTVALDRDRAVTRQWGISALPSTVILDRALRPRWRAAGDVAWDAPAARAVIAELLSSSSNPVPGAAAPEPSPSSGGLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRF3</accession>
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        <submittedName>
            <fullName evidence="5">Putative electron transfer flavoprotein alpha subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1178</name>
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    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169709.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="SMR" id="A8HRF3"/>
    <dbReference type="STRING" id="438753.AZC_1178"/>
    <dbReference type="EnsemblBacteria" id="BAF87176">
        <property type="protein sequence ID" value="BAF87176"/>
        <property type="gene ID" value="AZC_1178"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1178"/>
    <dbReference type="eggNOG" id="COG2025">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034178_4_0_5"/>
    <dbReference type="OMA" id="EWIARNR"/>
    <dbReference type="OrthoDB" id="1400253at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ETF" evidence="4">
        <location>
            <begin position="93"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="396" mass="40913" checksum="3AE0834817528D23" modified="2007-12-04" version="1">MSRLRRDPRAERAARALPTQGRPRLQLGTPVSEGRLRRNPFAERAAAEVQGRTRLRLDRAGGGPRSVSVASPPAAPEPRAPERRLVPEPAFLVLAVADVPGGHLSVHDRQVLGAARVLADAGGGAVVLLGGTLPQDAGAAGADRIACLPEADDPDRRAGALMAAIAALRPRHVLWPESRIGGDLARRVAVRIGEGLFCGAEQVSARAVARPARGRRVEQRREPPLLLTLAEGAAAPHGRTVHEARPIDLPLPARLDFESAILSIEEVPADPATVPLGEADFVLSAGNGVTDFAAFGALAEALGATPGASRMVCDAGLMPRAAQVGASGTVLSARCYFALGIAGAPQHLQGIAGCEHVVAVNTDLHAAMIERAGLAVVADAQAVMPALLALLAEEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRY2</accession>
    <name>A8HRY2_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4112</name>
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    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="HOGENOM" id="CLU_1999210_0_0_5"/>
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        <location>
            <begin position="27"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="61"/>
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        </location>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90181.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="124" mass="14036" checksum="3833F562D98959D4" modified="2007-12-04" version="1">MDTRNKVRGAAFHYNCMVKEVAMTASRSTERDGQSQTGAATRDQVASAPRGIPHGYDQSEFAPEQADRDFGRVRRSREADEERRHLRLADAAIGGRTRHVEQGEEKWDTDDELRVDGASRLYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="46" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSM9</accession>
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        <submittedName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4199</name>
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    <organism evidence="2 3">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF90197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_4199"/>
    <dbReference type="EnsemblBacteria" id="BAF90197">
        <property type="protein sequence ID" value="BAF90197"/>
        <property type="gene ID" value="AZC_4199"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4199"/>
    <dbReference type="eggNOG" id="ENOG5030AF6">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_080348_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720669" evidence="1">
        <location>
            <begin position="25"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90197.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="301" mass="32965" checksum="5AD142477EDF28CA" modified="2007-12-04" version="1">MGLPFRPRMVLALVAGLGLTAALAASPQAYEAMRSRYMAQLEKQRAEPPRPDPMLRVQEAAKARLMKQLTEALGPLAFQGMGPPELSPDALEPGAPDAARPIGLVFQDRAERTFLFVAPETRFADWLARQAREDGTFFPEGRKGIAANLANAALYTVTVGGETSFGTVVPLPLPSAPDEKVHAALGVFTADDVPFLLPRTLVIGRLAQGRIIVARQAIEDVVAPIPACTRLALRGKAQVRRFRAQVRAERREDDTFDDLWTIMRTANAAFEACITRELPRQPYYGALTARVRDLLDIVRGK</sequence>
</entry>
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    <accession>A8HUB5</accession>
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            <fullName evidence="4">Sulfate adenylyltransferase subunit 2</fullName>
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        <alternativeName>
            <fullName evidence="5">ATP-sulfurylase small subunit</fullName>
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        <alternativeName>
            <fullName evidence="6">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H(+) + sulfate = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <property type="gene ID" value="AZC_0927"/>
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    <dbReference type="eggNOG" id="COG0175">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="MMILAED"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd01713">
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        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="25"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022004"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="264" mass="30246" checksum="62730EAB76B237FD" modified="2007-12-04" version="1">MNRLDALEAQSIFILRDAFAQLRKVALLWSLGKDSNVMIWLARKAFFGRVPFPCMHVDTGRKFPEMYDFRDRYSKEWGLDLLLEECPPIESTDPTLPPAARSAARKTEGLRLALAKHGFDGVIAGIRRDEEPTRAKERFFSPRGTDGAWNVREQPPEFWDQYNTALTPGAHLRIHPILHWTEMDIWAYTKRENIPVIPLYFSNGGKRYRSLGDKDITFPVDSDASTLDEILAELAVTKTSERSGRAMDHESEDAFERLRTAGYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV56</accession>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Lee KB."/>
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                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family. DsbE subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4455"/>
    <dbReference type="EnsemblBacteria" id="BAF90453">
        <property type="protein sequence ID" value="BAF90453"/>
        <property type="gene ID" value="AZC_4455"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4455"/>
    <dbReference type="eggNOG" id="COG0526">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_042529_19_0_5"/>
    <dbReference type="OMA" id="MIGKPFP"/>
    <dbReference type="OrthoDB" id="1617952at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015036">
        <property type="term" value="F:disulfide oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03010">
        <property type="entry name" value="TlpA_like_DsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004799">
        <property type="entry name" value="Periplasmic_diS_OxRdtase_DsbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00385">
        <property type="entry name" value="dsbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="44"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="196" mass="20924" checksum="F534A7B37A527E62" modified="2007-12-04" version="1">MTTPETPRRRRPLFVILPLAVFLALAALFFVRLFAGDPSRIPSALVGKAAPAIDLQPLAGLSGSSGPVPGITSAQLKGKVALVNVWASWCVPCREEHPVLMGLSRDPRILLVGLNYKDQPDNARRFLGTFGLPYAAVGVDASGRSAIDWGVYGVPETFVLAPDGTIAQKFVGPLSEQTVREQLMPLIERLSGKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWT7</accession>
    <name>A8HWT7_AZOC5</name>
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        <submittedName>
            <fullName evidence="11">Nitrate reductase alpha subunit protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_1425</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169953.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1425"/>
    <dbReference type="EnsemblBacteria" id="BAF87423">
        <property type="protein sequence ID" value="BAF87423"/>
        <property type="gene ID" value="AZC_1425"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1425"/>
    <dbReference type="eggNOG" id="COG5013">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_14_1_5"/>
    <dbReference type="OMA" id="PFIHPFN"/>
    <dbReference type="OrthoDB" id="88184at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009325">
        <property type="term" value="C:nitrate reductase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008940">
        <property type="term" value="F:nitrate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042126">
        <property type="term" value="P:nitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02776">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037943">
        <property type="entry name" value="MopB_CT_Nitrate-R-NarG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006468">
        <property type="entry name" value="NarG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028189">
        <property type="entry name" value="Nitr_red_alph_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044906">
        <property type="entry name" value="Nitr_red_alph_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14710">
        <property type="entry name" value="Nitr_red_alph_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01580">
        <property type="entry name" value="narG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00490">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="10">
        <location>
            <begin position="43"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1252" mass="139002" checksum="0AB4D57D110B0018" modified="2007-12-04" version="1">MSHFLDRLTFFNKTVDDFSDGYGIVTNEDRSWEDGYRKRWQHDKIVRSTHGVNCTGSCSWKIYVKGGIVTWETQQTDYPRTRPDLPNHEPRGCARGASYSWYLYSGARVKYPMVRGRLLKLWRAARARLSPVAAWASIVEDADKRRSYMSVRGHGGLVRSTWDEVNELIGAANAYTVKAHGPDRVIGFSPIPAMSMVSYAAGSRYLSLLGGVCMSFYDWYCDLPPASPQTWGEQTDVPESADWYNAGFIIVWGSNVPQTRTPDAHFYTEVRYKGTKSAVVSPDYAEATKFADIWLNPKQGTDAALALAMGHVILREYHLDRSVPYFEDYARRYSDMPFLVRLVEKDGRLVPERLLRTSDLPGGLGEGNNPDWKTVAIDETTGDLVAPLGSIGYRWGEQAKWNLEEKDGAGRDTRLRLTLAGDDATIAPVDFPYFGGRATEHFVSTQHGEILTRNVPVRTLTGADGASVKVATVFDLMMANYGLDRGFGGEHVASSYDADVPFTPAWAERITGVKRDAIITVAREFATNAEKTNGRSMVILGAGLNHWYHMDMAYRGIINLLVFCGAIGQSGGGWSHYVGQEKLRPQTGWQPLAFGLDWSRPPRHMNSTSFFYAHTDQWRYETLTAAEIVSPTAPEGDWNQSFIDYNVKAERMGWLPSAPQLKQNPLEIAKAAKAAGMEPKDYVAQGLKSGALEMSCHDPDDPANWPRNMFVWRSNLLGSSGKGHEYFLKHLLGTTHGVMGKDLGPEGAVRNREVAWHEEAPKGKLDLLVTLDFRMSTTCVYSDIVLPTATWYEKNDLNTSDMHPFIHPLSAAVDPAWEARSDWDIYKGLAKAFSQVSGEVLGVEEDVVLTPIQHDSAGELAQALDVRDWARGETDPVPGRTMPAVAVVTRDYPNLYERFTALGPLMTKVGNGGKGIAWNTEHEVAALGALNGVKDRGAAAGLPRIETDIDATEVILMLAPETNGEVAVKAWEALSKATGREHAHLALPKEDEKIRYRDIQAQPRKIISSPTWSGIESEKVCYNAGYTNVHELIPWRTLTGRQQLYQDHLWMRAFGEGFVTWKPPVDLKTIAGAKGVKPNGNTEIVLNFLTPHQKWGIHSTYSDNLLMLTLNRGGPVVWISETDAKRAGIVDNDWVEVFNVNGALTARAVVSQRIAEGMMLMYHAQEKIVNTPGSEMTGNRGGIHNSVTRVVLKPTHMIGGYAQQAYGFNYYGTVGANRDEFIVVRKMARVDWLEGPLAPDHSPNTAPMEAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXA1</accession>
    <name>A8HXA1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1477</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170005.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1477"/>
    <dbReference type="EnsemblBacteria" id="BAF87475">
        <property type="protein sequence ID" value="BAF87475"/>
        <property type="gene ID" value="AZC_1477"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1477"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_3_5_5"/>
    <dbReference type="OMA" id="YVFVMGR"/>
    <dbReference type="OrthoDB" id="141801at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="68"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="520"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="638" mass="69271" checksum="3CC8D4D2BC673929" modified="2007-12-04" version="1">MLDQSRSRYGDTYARWKADPAAFWGDAARDIDWTSPPGTVFDGSLGVYGRWFPDAVGNTCFNAVDRHVASGRGSQTALIYDSPVTNSQRRLTYAELLEEVRILGAILTDMGVEKGDRVVIYMPMVPEAVVAMLACARIGAVHSVVFGGFAANELAVRIDDARPKVVLAASCGIEPNRVVPYKPLLDLAITIAAHKPTGCLVLQRPQLAGTLVEGRDHDWAERRAAFADAGRGADCVPVKATDPLYVLYTSGTTGKPKGVMRDTGGHMVALRWSMENLYGLKPGEVFWCASDIGWVVGHSYIVYGPLILGCTSVIYEGKPVGTPDPGAFWRMIEEHKVVALFTAPTALRAIKKEDPEATHLKGRDLSQFRTLFLAGERADPDTILWAEQHLKVPVVDHWWQTETGWAIAANPVGLGLLPIKPGSPTVAMPGYDVQVVDESAKPVPAGTMGSIVVKLPLPPGCLPTLWQQDERFREAYLDEFPGFYKTSDAGFLDEDGYIFVMGRTDDIINVAGHRLSTGGMEEVLASHPDVAECAVIGVKDALKGEVPCGFVVLKAGERRAPNIIEKELVNLVRDRIGPVAAFKLAFTVNRLPKTRSGKILRGTMKKIADAESWSAPATIDDPVALDEIAEVLKERGFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="101" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY19</accession>
    <name>A8HY19_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Potassium-transporting ATPase ATP-binding subunit</fullName>
            <ecNumber evidence="12">7.2.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">ATP phosphohydrolase [potassium-transporting] B chain</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-binding and translocating subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Potassium-translocating ATPase B chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">kdpB</name>
        <name evidence="13" type="ordered locus">AZC_1566</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="12">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.</text>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Xanthobacteraceae</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4574"/>
    <dbReference type="EnsemblBacteria" id="BAF90572">
        <property type="protein sequence ID" value="BAF90572"/>
        <property type="gene ID" value="AZC_4574"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4574"/>
    <dbReference type="HOGENOM" id="CLU_2230943_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF90572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="105" mass="11790" checksum="901CC5A690900A04" modified="2007-12-04" version="1">MCVTDDAANPDPVTPVRISHHVDEIWEDHPGGTLQEFYNFLIYEFEVAGAVFRARAYADDFNCVTLYGPFDRAGEAPAATNPEAEAQVTAYLERRFGEVRRQPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZK5</accession>
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        <submittedName>
            <fullName evidence="9">Putative acyl-CoA carboxylase alpha chain protein</fullName>
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        <name evidence="9" type="ordered locus">AZC_4593</name>
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    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173112.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_4593"/>
    <dbReference type="EnsemblBacteria" id="BAF90591">
        <property type="protein sequence ID" value="BAF90591"/>
        <property type="gene ID" value="AZC_4593"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4593"/>
    <dbReference type="eggNOG" id="COG4770">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000395_3_1_5"/>
    <dbReference type="OMA" id="IYYDPML"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF51246">
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="8">
        <location>
            <begin position="2"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="121"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="584"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
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            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90591.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="665" mass="70154" checksum="39CDAB197632FBC9" modified="2007-12-04" version="1">MSLRKLLIANRGEIAVRIMRTARAMGIATVAVYSEADAHALHVETADEAWPIGPAPARESYLKIDAIIAAAKASGADAIHPGYGFLSENAAFGEACAEASITFVGPPASAIRAMGSKSAAKALMEKAGVPLVPGYHGEDQDPALLAAEAARIGYPVLIKASAGGGGKGMKVVASAGEFADALASAQREARNAFGDDRVLIEKYLTRPRHIEVQVFADSHGNAVYLNERDCSIQRRHQKVVEEAPAPGLSPERRAAMGQAAVDAARAVGYVGAGTVEFIAEGEDFFFMEMNTRLQVEHPVTEAITGQDLVEWQLRVARGERLPLTQADVPLEGAAIEVRLYAEDPQKDFLPQVGRLDHLRLPDDLPGVRVDTGVRAGDSVSIHYDPMIAKIIARGADRAEAVGRLAAALAATEVVGLPTNRAFLAAIANHPAFTAADLDTGFIGRFGADLLPAPEPLDDRTLALAALSILLEEARVSATATDPADPFSPWGLAPGWRLNRAAHVDLTFSDGGARLVVRAHYRARGFALDLPGGTLEVEGRLEADGTMEARLAGVKLRARVVRSGMKLTVFAGGTERLIEFVDPRRASIDATGTAGRLVAPMPGTVIRVAVEPGQSVQKGAALVVVEAMKMEHTVTAPRDGTVARVLFAAGDLVDEGAELLVLEEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZR4</accession>
    <name>A8HZR4_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">Gamma-glutamylcyclotransferase</fullName>
            <ecNumber evidence="1">4.3.2.7</ecNumber>
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    </protein>
    <gene>
        <name evidence="2" type="primary">chaC</name>
        <name evidence="2" type="ordered locus">AZC_4616</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glutathione = 5-oxo-L-proline + L-cysteinylglycine</text>
            <dbReference type="Rhea" id="RHEA:47724"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58402"/>
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            <dbReference type="EC" id="4.3.2.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-glutamylcyclotransferase family.</text>
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    <dbReference type="EC" id="4.3.2.7" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90614.1"/>
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        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ChaC"/>
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        <property type="entry name" value="GGCT-like"/>
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        <property type="entry name" value="GGCT-like_sf"/>
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    </dbReference>
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        <property type="entry name" value="ChaC"/>
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    </dbReference>
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        <property type="entry name" value="SSF110857"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="253" mass="27819" checksum="95E3A5C9E3DEF980" modified="2007-12-04" version="1">MKAQAAPVAAPLMARAVLPRDKPATFRRRALLSPHNRRINQARSLLRLCGNSPEFHPAMSADSPSPRMSHPPVPVPAHDPWVFGYGSLIWNPGFPFAERVEATLLGAHRALCIYSFHHRGTPEHPGLVLGLDLGGSCKGVAYRVAAADWPQVHAYLTEREQISGVYRETSRRVRLKGHEDLAASAVAYVANRAHPQYARGLSLEDQLHLVRRSHGRSGPNRDYVLATVDALATMGIEDRGLSWIAHHLRGGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I022</accession>
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        <submittedName>
            <fullName evidence="3">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4656</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4656"/>
    <dbReference type="EnsemblBacteria" id="BAF90654">
        <property type="protein sequence ID" value="BAF90654"/>
        <property type="gene ID" value="AZC_4656"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4656"/>
    <dbReference type="eggNOG" id="COG4566">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000445_69_8_5"/>
    <dbReference type="OMA" id="VICMSAH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="40"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="162" mass="17646" checksum="106ED5465F5B97D0" modified="2007-12-04" version="1">MPFRRDGEGVRASTQGGGSREAHMLLIGEDKAADAPASPVVVVVDDDPAVRGSLKFALELEGFDVRIFATAAEMLDQDIETLPGSGCLIVDYNLPGLNGLDLLRELKQRQVTWPAILITTHPTEQVRRRATSAGVAIVEKPLFSNALSDAVRETFRRPFPHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0I8</accession>
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            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
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            <alternativeName>
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        <domain>
            <recommendedName>
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            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
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        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">ribD</name>
        <name evidence="15" type="ordered locus">AZC_1263</name>
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
    <dbReference type="EC" id="1.1.1.193" evidence="10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169794.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1263"/>
    <dbReference type="EnsemblBacteria" id="BAF87261">
        <property type="protein sequence ID" value="BAF87261"/>
        <property type="gene ID" value="AZC_1263"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1263"/>
    <dbReference type="eggNOG" id="COG0117">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG1985">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036590_1_1_5"/>
    <dbReference type="OMA" id="PYIILKW"/>
    <dbReference type="OrthoDB" id="1775351at2"/>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
        <property type="entry name" value="RibD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="8 10 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="17"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="318"/>
            <end position="324"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAF87261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="384" mass="39608" checksum="DC7B5D48CECFAAA7" modified="2007-12-04" version="1">MSAAAVGLGRAGVFSPEEDEALMAEALAVGQLGLGRTWPNPSVGAVVVRPTSAGPQILGRAGTAPAGRPHAEPLALAQAGDAARGATLYVTLEPCSHFGRTPPCADAVIAAGITRVVAAVEDPDPRVRGRGVARMRAAGLWVTVGVGAERALEDHAGHISRVTRGRPHVLLKMAVSADGKAGLEGPRPAAITGEEARARVHLMRAHADAIMVGIGTVLADDPQLTVRLPGMEGRSPVRIVLDGDLRLPTTCGLVRTAEQVPVWAIAAEDAPAEREKALVDAGVQVLRAPRAASGRLDLPAVMKLLGLLGVTRLMVEGGPQVAAALLDEGLVDEVAVLRSPDALGAGGLDALAGRPLARLTEPVGFAVVERTELGRDSLMRLRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0L3</accession>
    <name>A8I0L3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arsenate reductase</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1271</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <topology evidence="1 6">Multi-pass membrane protein</topology>
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    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF90711">
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    <dbReference type="eggNOG" id="COG0306">
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
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            <end position="48"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="513"/>
            <end position="534"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU363058"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF90711.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="538" mass="57099" checksum="F282E00ED6DACEAA" modified="2007-12-04" version="1">MSRTVPHPTAAPLRTAPVALDRAPRPRDIALFFAALFGGLAYVFWSIWSDVQQAAPGSLTLAPFLLLALALVIALGFEFVNGFHDTANAVATVIYTHSLPPHFAVIWSGVWNFIGVLVSTGTVAFSVVSLLPVELILHVGSGAGLAMVFALLLAAIIWNLGTWFLGLPASSSHTLIGSIVGVGIANQLLQDRNGFSGVDWEQASSVGYALLLSPVVGFMGAGLLLLSLKALVKQPELYREPKPGTAPPWWIRGLLVLTCTGVSFAHGSNDGQKGMGLIMLILIGIVPTTYALNRAVDPVDVAQFRALSREAAQVLTQIVPPGVRISDPRRILSDYVRDRRRTADTLPALARITDEIGEAVARHASLAQVPAAAVSNMRNDMYLASETIRLLLRQPDATITPSTRSTLVAFKRALDQATKFIPLWVKVAVAIALGLGTMVGWKRIVVTVGSRIGKSHLTYAQGGAAETVAMGTILAADAFGLPVSTTHVLSSGVAGTMAANRSGLQWGTVRNLALAWVLTLPVAILLSGVLYALLRQVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
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    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF87827">
        <property type="protein sequence ID" value="BAF87827"/>
        <property type="gene ID" value="AZC_1829"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1829"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003827_3_0_5"/>
    <dbReference type="OMA" id="MTSEHYW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06195">
        <property type="entry name" value="FNR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033892">
        <property type="entry name" value="FNR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
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        <location>
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    <evidence type="ECO:0000256" key="1">
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        <source>
            <dbReference type="EMBL" id="BAF87827.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
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            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="289" mass="32341" checksum="C039D7D5800A9BAC" modified="2007-12-04" version="1">MKAMLSQCTAVIGCAPDGDRPRAGRLSVRVGFMSNLNEETVKSVHHWTDNLFTFTTTRDPGFRFLNGQFVMIGLMVEGKPLLRAYSLASANYEEDLQFFSIKVQNGPLTSRLQHLKPGDKILVGRKATGTLIQDNLTPGKRLYLLSTGTGLAPFLSVVKDPDAYERFEQIILIHGCRTVAELAYDDFLTKDLPNDEYIGEQVREKLIYYPTVTREPFRNQGRITALIESGKLFTDIGVPVLNPAEDRLMLCGSPQMLKDVVEQLEARGFNEGSQSSPAEYVIEKAFVER</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HpcH/HpaI aldolase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170369.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_1841"/>
    <dbReference type="EnsemblBacteria" id="BAF87839">
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    <dbReference type="KEGG" id="azc:AZC_1841"/>
    <dbReference type="eggNOG" id="COG2301">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_044864_2_0_5"/>
    <dbReference type="OMA" id="FLNEGDW"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Aldolase/citrate-lyase_domain"/>
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    <dbReference type="InterPro" id="IPR011206">
        <property type="entry name" value="Citrate_lyase_beta/mcl1/mcl2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
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    <dbReference type="Pfam" id="PF03328">
        <property type="entry name" value="HpcH_HpaI"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HpcH_HpaI" evidence="6">
        <location>
            <begin position="12"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="67"/>
        </location>
        <ligand>
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    <feature type="binding site" evidence="4 5">
        <location>
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    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR015582-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="269" mass="27879" checksum="C578061B34C383C7" modified="2007-12-04" version="1">MTTFLHTERLVALFVPGDRPERFGKALAAGADAVIVDLEDAVAPGDKGKARDAIAAHWPTEGRLLLRINGCGTPFLADDLALARRLRLSGIILPKAEQAQNISTVHAAVPDVPVIALIESALGLANARALAATHGVARLAFGSIDYCADLGSSHSREALLMARSELVLASRLARRAGPIDGVTATVADATLARDDAAYAAGLGFAGKLCIHPSQIAPVLAGFAPSPSDIAWAQRILAAASEGAVKVDGAMVDAPVRIRAEQILKRAEIG</sequence>
</entry>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1878"/>
    <dbReference type="EnsemblBacteria" id="BAF87876">
        <property type="protein sequence ID" value="BAF87876"/>
        <property type="gene ID" value="AZC_1878"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1878"/>
    <dbReference type="eggNOG" id="COG0819">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_077537_1_0_5"/>
    <dbReference type="OMA" id="FYIIQDY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
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        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
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        <property type="entry name" value="Thiaminase-2/PQQC"/>
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        <property type="entry name" value="TENA_THI-4"/>
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        <property type="entry name" value="SSF48613"/>
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    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TENA_THI-4" evidence="1">
        <location>
            <begin position="25"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="231" mass="25250" checksum="BD2BE8D7398A2DDB" modified="2007-12-04" version="1">MSDTGAGRNGMDVFTRLKASALADWQSYVDHDFVRQLGAGTLPEAAFRAYLVQDYLFLIQFARAYALAAYKSRTLNDIRIAQEGVAAILAETELHVRLCARWGLSRADLDAAREEQATVAYTRFVLDCGAAGDLLDLHTALAPCVIGYAEIGRALAPDGADGPNDHPYREWIGEYAGAGYQSVAATARRHLDDLAARTMTDRRFAELSALFGQAARLEADFWQMGLDLGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2Z3</accession>
    <name>A8I2Z3_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter substrate binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1959</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170486.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1959"/>
    <dbReference type="EnsemblBacteria" id="BAF87957">
        <property type="protein sequence ID" value="BAF87957"/>
        <property type="gene ID" value="AZC_1959"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1959"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_2_5"/>
    <dbReference type="OMA" id="WQAIKWA"/>
    <dbReference type="OrthoDB" id="162819at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030288">
        <property type="term" value="C:outer membrane-bounded periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723297" evidence="4">
        <location>
            <begin position="33"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="91"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="543" mass="60190" checksum="F9E9433A0AE1BC64" modified="2007-12-04" version="1">MIDVFLKPTRRQWLMGATALVAVSLTAPAAHAQSRAETLRYVTGAVVNTLDPTMPGSTREAFAVSLSTYDRLVSFGRKQLNGKWVFDLDTVRGELAESYDVSPDGLKITFHLRKDAKFQDGTPVTAEDVKWSLDRAVTANSLAKAQLLTGSLTSPDQFKVIDPYTFEVTLPKPDKLALPNLATVYPVIFNSKVAKAHATADDPWAQNWLKENTAGSGAFVIETFKPAEQVILKRNDAWNRGPANSQAAFKRLIVQTVPEASTRANLVERGDADIVIDLQPTDAAALEAKGKLKVISTPQYNAISFISFNNKIPPFDNVNVRKAIAYALPYDDMFKAALFGRGFPLYGATWTDGKAPSGGFPIPQPVKLDLAKAKEYLAAAGMPDGFSTTFSFNVGQANVAEPMAALLKESLAKIGIKVEIQKLPDAQMSTLINEKKLPFFTENIVAWLPSMDYFYRNFYIGNIRWNYSSLDNPQITEIAQAARFEQDKAKYEAMGRELNTLNFEIMPQIPIWQASQDAVMAPSIEGYTYQFHRQVDYRDLSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3L0</accession>
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        <submittedName>
            <fullName evidence="3">Putative transcriptional regulator</fullName>
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    <gene>
        <name evidence="3" type="ordered locus">AZC_1627</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="EnsemblBacteria" id="BAF87625">
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        <property type="gene ID" value="AZC_1627"/>
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        <source>
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        <source>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
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    <dbReference type="InterPro" id="IPR018130">
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        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
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        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Ribosomal_S2"/>
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    <evidence type="ECO:0000255" key="1">
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    </evidence>
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    <accession>A8I4G1</accession>
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        <submittedName>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87725.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF87725">
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    <dbReference type="KEGG" id="azc:AZC_1727"/>
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        <property type="entry name" value="Extensin-like_C"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724131" evidence="2">
        <location>
            <begin position="28"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="Extensin-like_C" evidence="3">
        <location>
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        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="323" mass="33597" checksum="8AD845F5D55D9BF0" modified="2007-12-04" version="1">MRRGVRALAGCVVLLLLASNGASPAAAAPQRPPASVSQPHPPPAPVRAAKRQGRLPPDGAPLPVPSPLRMAVDAVKRQGLLGAPTVPLPLPRPVEIGGKPAAPPVAEAPTPTPQPKPDIAPEDSAPTPEPMEGEAYAACLKTFEARGGEPVPREQGEGTSDGDGACTIPGAVTFSRIKLVEGGTVALESAVTVRCTLAVELAGWVREDLAPLVQRQGGELSGLTGVGGQACRPRNGQKGAQISEHASGNAFDLLGLKLKDGKVVELWKAEAGTKDLRAGVRESACARFRTVLGPGADSAHANHVHLDMRQRRNDFRMCQWNVD</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1733"/>
    <dbReference type="EnsemblBacteria" id="BAF87731">
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        <property type="gene ID" value="AZC_1733"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1733"/>
    <dbReference type="eggNOG" id="COG1354">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="ScpA"/>
    </dbReference>
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        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="298"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="298" mass="32744" checksum="044177FB1FF167A0" modified="2007-12-04" version="1">MATGAPPSEEEGPAGPGASDFMEDQLPAAGEGAFVVDLDGFEGPLDLLLTLARTQKVDLHRISILALADQYLAFIEEARRVRLELAADYLVMAAWLAYLKSRLLLPAPPKEDGPSAEELAAAFTRRLRHLERIRKAAEQLMARERLGVTVFPRTPPDESNPDTRPVVFTATLYDLLSAYATQRQKQALSFVTLKTRMVWSLADARERLERLLGTTLGDWMRLDEFLIDYMTTPEQKATALASSFSATLEMVREGKLDIRQDAPFAPLWLRSRAGQGADPLAPSSGEDTAEDGTKDAGA</sequence>
</entry>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_1742"/>
    <dbReference type="EnsemblBacteria" id="BAF87740">
        <property type="protein sequence ID" value="BAF87740"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87740.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    </evidence>
    <sequence length="115" mass="11200" checksum="0CAD20521AE2E877" modified="2007-12-04" version="1">MAVVALIVLFLALASAVASWGVAVTEGLKAKGAAEAAGGSHGSVSMAHLVLWPFAARLLSGPAADPARRVGKAQVAFIAALMIAVAAVSVYTNLSAVRPPSAAPAAPGAAPSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4L2</accession>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF87743"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87743.1"/>
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    </evidence>
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        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="1">Belongs to the HpcH/HpaI aldolase family.</text>
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        <property type="protein sequence ID" value="BAF87796.1"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005568"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03328"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87796.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="272" mass="28871" checksum="91A5131C0CA176ED" modified="2007-12-04" version="1">MPDPSAPTCALRGNGGTHPFARRSLMSQSLAQFAFWLSSPSFPHIEIARGAGFTAVVLDIEHGTFNLDDLDRVIPFCRALGIKVYAKVLGPLTEPIQQALDFGADAIIIPHIGALDHAKAVTAATKYPPLGVRSYAGGRTMGYGPVDDSFSANENARTKCWPMIESREALNDVEAIAALPTVDGLFAGPTDLSMAAGNPRYSFSESDKNDIARIGAAARAAGKPWVLPAWTAPERAFGKLHRADITVVGAQYALIRSAFHGLVDSLGSEGLL</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="8 9" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
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    <sequence length="325" mass="35792" checksum="AD299CD41F04EA97" modified="2007-12-04" version="1">MPTRGTRTSPFVRGHRFCTATASIWLCECVFPLWWGRRAQLAREPADFRLARPLPVPPGTGHHTGCPMTIDLGSTYLTYSYLSKNYDKALEQEATTGSTKLETANFEKSIGSITSVDDFVNNYRVFTYAMKAYGLEDMAYAKAYMKKVLESDLTDDSSFANSLSDGRFKAFAQAFQSLTYGEAVSSDTVSTVETKYAQQTMEDNAGASDTGVQLALYFKRNASTVTSAYSILADEALYKVVKATYNIPDEMSNAGIEAQAALISKHIDIEELQDPDYVDKLLKQFSIKYDIENNSASDPVLQLFNDTSSVSSDTAGAILNLKYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7B1</accession>
    <name>A8I7B1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome bo(3) ubiquinol oxidase subunit 4</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Cytochrome o ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Oxidase bo(3) subunit 4</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Ubiquinol oxidase polypeptide IV</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquinol oxidase subunit 4</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ordered locus">AZC_2101</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="17 18" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooctamer of two A chains, two B chains, two C chains and two D chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase bacterial subunit 4 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170628.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2101"/>
    <dbReference type="EnsemblBacteria" id="BAF88099">
        <property type="protein sequence ID" value="BAF88099"/>
        <property type="gene ID" value="AZC_2101"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2101"/>
    <dbReference type="eggNOG" id="COG3125">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_140945_0_0_5"/>
    <dbReference type="OMA" id="IVVHMVF"/>
    <dbReference type="OrthoDB" id="2088013at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009486">
        <property type="term" value="F:cytochrome bo3 ubiquinol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015990">
        <property type="term" value="P:electron transport coupled proton transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014210">
        <property type="entry name" value="Cyt_o_ubiqinol_oxidase_su4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02847">
        <property type="entry name" value="CyoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00032185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="BAF88099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="132" mass="14263" checksum="C38852E336843E31" modified="2007-12-04" version="1">MSANGHAHSGAAHGHDAHGAHGEDHGHGSFKSYMTGFILSVILTAIPFWLVMTNALGNNQLTAIVIMAFAVVQIVVHMIYFLHMTGKVEGGWSMLALIFTVIVVVIALSGSLWVMYHLNANMMPSHDMRIAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="53" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7N9</accession>
    <name>A8I7N9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mu-like prophage protein gp29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2143</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </evidence>
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    </evidence>
    <sequence length="211" mass="22147" checksum="83D16E5EEEA02D07" modified="2007-12-04" version="1">MIAPVSLASLIAADPVQALKAAIVARLGALMPGVKIVSHPGRIDIADVVAKSVVAAPGVAVGWTRIRARRLIDGGYGLAVEFAAYVVVEDAVVDGRRVERETLGLALGHRLLAILEDADAQTWGLGNVLPPEADPAPELKPMFTVRDAAAGAAYYAVTWTQLVADLGRSLFASDRPAVTELDGTGIAPFADVTFPDQIPPEVLALLRQERA</sequence>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="56"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000313" key="2">
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            <dbReference type="EMBL" id="BAF88153.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    <sequence length="80" mass="8425" checksum="8241257A0ADCF46D" modified="2007-12-04" version="1">MTSDLLKLPFVVTEAAGPKVAGRSARVGETLHLTEFEARTELLAGVIRPAPADPEAPQTSGNSDTGTTTGEAEPRPARRR</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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    <sequence length="751" mass="80962" checksum="8B0028D1E027008E" modified="2007-12-04" version="1">MVVQRKPHLAHWGAFTALVEDGQLVGCEPFAADPAPSPLLGSIVPSVYSDRRIQKPMVRESFLKHGAAAGGEGRGREPMVEVSWETALDLAAREISRVEVEHGRGALFAGSYGWSSAGRLHHARSLVRRFYFSGGGAIDQVGNYSWGTAQFLLPHIIGTYQPLTGRATSWPSILKHCRLFLAFGGLALKNGQMASGGAAEHTQEHWLRELAKAGIPVINVSPTRGDCPDFLNAEWVPIRPTTDAAFLLALLSEVLRIQGADLAFLATHTVGFEPLAAYVRGESDGVPKTPEWAQDICGVPAERIRQIAARLVGVRSYITCSFAVQRAENGEQPYWLAIALASVLGQVGLPGGGFGFGHGSMNGVGNPRPATPGPEMAVGANPLKRAIPAARITEMLEAPGTSYPFNGRTETYPDVRLIHWAGGNPFHHHQDLNRFSRAWQKPETIIVNEIWWTPTARRADIVLPVTTTLERNDIGGSSRDRYVIAMHQAIAPLHAARSDFDIFADLAERLGHGVAFTGGLDEQGWIERIYADCAAANAKAGITFPDFETFWQDGSFELPRPAQDFVLFADFRADPQAHPLATPSGRIELYSSAIASFALSDCPPHPVWRAPGEWLGSAGAKRHPLHLVTVQPSDRLHSQLDFAPLPQGNKVDGREALLMHPDDAAARGCVAGRTVRVFNDRGALLAGLVLDEGVHRGVVVMATGAWFDPDPSAPDAPERAGTVNVLTRDVGTSSLTQGPNAMSCLVEVAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8J6</accession>
    <name>A8I8J6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">lysR</name>
        <name evidence="3" type="ordered locus">AZC_2670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171194.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2670"/>
    <dbReference type="EnsemblBacteria" id="BAF88668">
        <property type="protein sequence ID" value="BAF88668"/>
        <property type="gene ID" value="AZC_2670"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2670"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039613_16_3_5"/>
    <dbReference type="OMA" id="RFQAMQV"/>
    <dbReference type="OrthoDB" id="1661500at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="305" mass="33942" checksum="C82AD99DDCAE986D" modified="2007-12-04" version="1">MDQLAAMRAFVRVVESGSFTRAADILALPKATLSKQIQQLETHLSTRLLHRTTRQVTVTPDGAAYYERALAILTDVDELDGSLSTNLTCPRGRLRIDISPSLATGILMPALPDFFSRYPEIHIDIGCTDRPVDLVGENVDCVIRVGEIRNSSLIARRIGELNFAAAAAPSYIARHGEIQHPKDFEKDHVMVRYFSATTAHYYAFDFIRDAEEVEVLGRYSVALNDGNAYVSAGLAGLGVILCPIFMMQEHLDAGTLVRVLPEWHTQPMPIHVVYPPSRHISNRLRVFVDWVAELFARSTRARAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I907</accession>
    <name>A8I907_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YbaK protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ybaK</name>
        <name evidence="2" type="ordered locus">AZC_2729</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171253.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2729"/>
    <dbReference type="EnsemblBacteria" id="BAF88727">
        <property type="protein sequence ID" value="BAF88727"/>
        <property type="gene ID" value="AZC_2729"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2729"/>
    <dbReference type="eggNOG" id="COG2606">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_094875_0_0_5"/>
    <dbReference type="OMA" id="VMLPATG"/>
    <dbReference type="OrthoDB" id="1935578at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="26"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="154" mass="15786" checksum="A01C1335C365FF7E" modified="2007-12-04" version="1">MEAVDRVREALKAADHPDSIAAFESGTRSAADAAASVGCDVAQIAKSIIFRAGDEPVLVVASGSNRIDRKKVAAVTGLAVKPADPAWVQEKTGFAVGGVAPVGHACGVTTLIDADLMALDPVWAAAGSPMHVFRTTPQELVRLTGGAVADVRQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8I965</accession>
    <name>A8I965_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2749</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171273.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2749"/>
    <dbReference type="EnsemblBacteria" id="BAF88747">
        <property type="protein sequence ID" value="BAF88747"/>
        <property type="gene ID" value="AZC_2749"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2749"/>
    <dbReference type="eggNOG" id="COG2317">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032916_1_0_5"/>
    <dbReference type="OMA" id="EFGHALY"/>
    <dbReference type="OrthoDB" id="239313at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="497" mass="54924" checksum="54198D1523BBAD1A" modified="2007-12-04" version="1">MTAYSALSAHFGRAAALSNALGILQWDSDTMMPKGAVGTRAESMALLRVLAHEMVTDARIGDWIADAEADTALDAWAKANVREIRRVWTVETAVPADLVEASSKAISICEMTWRQARADADFKALLPYLSEVLRLQREIGTAKGEKLGLSAYDALLNDYEPGGRSARIDALFADLAAFLPGFLDEVLAVQGRRPQDAPLVGPFPVEAQRAFGVKMMGIVGYDFERGRLDVSTHPFCGGADNDVRITTRYNTDDFTHALMGVMHETGHALYEQGRPQAVLGQPVSQARSMSVHESQSLLMEMQACRSREFLRFAAPLMREAFGGEGPAWEADALWRRYTHVERGFIRVDADEVTYPAHVILRYRLEKALIADEMPLSELPAAWNAQMQELVGVTPPDDRLGCLQDVHWPSGGWGYFPTYTLGAMTAAQIFDAAKRADADILPGIARGDFKPLVTWLRANIHGQGSLYETDDLLTRATGRPLDASVFKAHLRRRYIEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8I978</accession>
    <name>A8I978_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_2754</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171278.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2754"/>
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    <dbReference type="OrthoDB" id="1031685at2"/>
    <dbReference type="Proteomes" id="UP000000270">
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    </dbReference>
    <dbReference type="GO" id="GO:0016021">
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0000155">
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        <property type="entry name" value="HATPase_C"/>
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    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="HisK_dim/P"/>
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    <dbReference type="InterPro" id="IPR036097">
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="160"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="220"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="420" mass="45778" checksum="D542F56FA0159816" modified="2007-12-04" version="1">MNSLRTKLIALLVTALVVVIIIATVVFFYLVAPRPQRPEGERHMAEASVVALIIGLLKDQAPPLHLPAISNGEPDGMYDPMATQELAHLLAQLGVTEPVRVYRREFGRHAAAVPLPDGRYVVLPIQLMPPGPPGDLPFFLIGWLALVALGTTGVVAVAVYRMTKPLEIIERAVAEIGPDGELPRLEEKGTTEVRAAAVAINRLSDRLRSSMESRMRIVAAAAHDLRTPLTRMRLRAEFLEEEREQWLSDLSELDRIADSAIRLVREEVESAGDEPVDLHTLARDLERELKQTDLSIELVRAEPVTVAGRPMALKRAMRNLMVNAATHGRSARMAVSAEGGKGVLVIEDDGPGIPDALMARVFEPFFRVDPARQAIIPGAGLGLAIAHEIVTRHGGRLSLSNRPSGGLLQRMELPAATETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9H6</accession>
    <name>A8I9H6_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
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    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2791</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171315.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2791"/>
    <dbReference type="EnsemblBacteria" id="BAF88789">
        <property type="protein sequence ID" value="BAF88789"/>
        <property type="gene ID" value="AZC_2791"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2791"/>
    <dbReference type="eggNOG" id="COG0410">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_2_5"/>
    <dbReference type="OMA" id="IVEQMAN"/>
    <dbReference type="OrthoDB" id="1475841at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="3"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="234" mass="25825" checksum="77EC4DD5FE2D4E0F" modified="2007-12-04" version="1">MKLEVSGLNSHYGPAHILFDVGFEVGAGEVVALLGRNGAGKSTTFRSVVGLVSQRSGQIRFDGEDVSRLPTYEIVRRGLGYVPEDRRIFTELTVEENFTVGRQPARPGVATWTPERIYEIFPNLGEMRKRPGGQMSGGEQQMLTIGRTLMGNPSLVLLDEPSEGLAPKIVEQMADAILTMKREGLSIVISEQNLHFAKLISDRAYIIEKGRMRFSGTMAELEANPEIRDAYLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9H9</accession>
    <name>A8I9H9_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter related protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="6 7">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <evidence type="ECO:0000313" key="2">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2491"/>
    <dbReference type="EnsemblBacteria" id="BAF88489">
        <property type="protein sequence ID" value="BAF88489"/>
        <property type="gene ID" value="AZC_2491"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2491"/>
    <dbReference type="eggNOG" id="COG0583">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_039613_6_0_5"/>
    <dbReference type="OMA" id="ERSIVMV"/>
    <dbReference type="OrthoDB" id="990666at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="313" mass="33843" checksum="F1EA9608C31A89FB" modified="2007-12-04" version="1">MSMNMNLRQLRAFVAVAQTGSFSRAARLLGLSQSALSQAVQQLEADLGVRLLDRTTRSVQLSAIGREFLPGVQRVLADLDHQLQDLRDLKEHRRGHVTVTCVPSVALRLLPQVLAQFQEAHPMVSVAVREAPRHQIITALRSGDAELGVANVPGDDPDLDSTFLLTDSFALVMRRDHPLAAHESVTWEEAGQAGLIAMAPGTGIRLEMERGLPAPAVPHHEAEHPATLLAMVEAGVGVAPLPGLAWPRPDHAGLTFRPLVEPRVERQLFLIKRAGRDLTPAGRALHRAILAGVAKEDFSGAAVPRGGRRPRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAJ3</accession>
    <name>A8IAJ3_AZOC5</name>
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        <submittedName>
            <fullName evidence="11">Helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ordered locus">AZC_2515</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2515"/>
    <dbReference type="EnsemblBacteria" id="BAF88513">
        <property type="protein sequence ID" value="BAF88513"/>
        <property type="gene ID" value="AZC_2515"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2515"/>
    <dbReference type="eggNOG" id="COG0513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003041_28_1_5"/>
    <dbReference type="OMA" id="EIKQESM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="95"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="297"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="433"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="64"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="440"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="582" mass="65044" checksum="508DA339186D3AC9" modified="2007-12-04" version="1">MACAVRPEPAHGINIDTAHNASIFYRVVRDVFESKRADRRPLVWARTRHGTFDQRGAATSSDPMSFSELGLSEKVLSAVAATGYTTPTPIQAQAIPHVLARRDVLGLAQTGTGKTAAFTLPMLTLLEQGRARARMPRTLILEPTRELAAQVEENFVRYGKNHKLNVALLIGGVSFGDQDTKLLRGVDVLIATPGRLLDHVERGRLLLSGIEVLVIDEADRMLDMGFIPDIERICKLVPFTRQTLFFSATMPPEIQRLVSQFLSNPVRVEVSKPASANTSITQLLVASGREDYEKRETLRELIRNADQLQNGIVFCNRKRDVAVVHRSLQKHGFNVVCLHGDMDQHARTQALDQFRTGEATLLVASDVAARGLDIPAVSHVFNYDVPHHSEDYVHRIGRTGRAGRTGTAIMLVTHDDAKSLAAIEKLIGNAIPWQGEPLGEAPPREKRSRGGDRREERGERSERNKRSGRGRSERKAEVEDGVEVRAERAPRPAREGRPEREPRPEREPRAERQPRPEREARPEREARPEREARPEGERARKPRPETADAASRNRRDRSASEPADMSHLPAFLLRPVRIKASS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-03-24" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAX3</accession>
    <name>MIAA_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="1">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="1">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="1">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="1">IPP transferase</shortName>
            <shortName evidence="1">IPPT</shortName>
            <shortName evidence="1">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">miaA</name>
        <name type="ordered locus">AZC_2575</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the IPP transferase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171099.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAX3"/>
    <dbReference type="SMR" id="A8IAX3"/>
    <dbReference type="STRING" id="438753.AZC_2575"/>
    <dbReference type="PRIDE" id="A8IAX3"/>
    <dbReference type="EnsemblBacteria" id="BAF88573">
        <property type="protein sequence ID" value="BAF88573"/>
        <property type="gene ID" value="AZC_2575"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2575"/>
    <dbReference type="eggNOG" id="COG0324">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032616_0_1_5"/>
    <dbReference type="OMA" id="YAKRQYT"/>
    <dbReference type="OrthoDB" id="1069591at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0460">Magnesium</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_1000098640" description="tRNA dimethylallyltransferase">
        <location>
            <begin position="1"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <begin position="43"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <begin position="167"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="20"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <sequence length="312" mass="34779" checksum="C4821FE34FC842DD" modified="2007-12-04" version="1">MGLRDSEALKPLAVLIAGPTASGKSALALDLAERTDGVIINADSMQVYGDLRILTARPSPEEEMRVPHRLYGHVDGAADYSVARWIADAAAAMATARAEGRLPIVIGGTGLYFRALTRGLAPIPEIPEEVRQRVRRMAEDEVTVVLHARLATRDPEAAVRLQPQDRQRILRALEVFEATGQPLSQWQRATHRPVLEEASAVRFVLEVERETLRGRIDRRFETMMEAGALAEVERLAARELPADRTILKAHGAPALTRYLRGEMSRADAIAEGQNDTRRYAKRQVTWFRHQMPDWMRGTPDTALDQLTGTLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB04</accession>
    <name>A8IB04_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171114.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2590"/>
    <dbReference type="EnsemblBacteria" id="BAF88588">
        <property type="protein sequence ID" value="BAF88588"/>
        <property type="gene ID" value="AZC_2590"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2590"/>
    <dbReference type="HOGENOM" id="CLU_410317_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="669" mass="72056" checksum="BD1C9316D79B85DC" modified="2007-12-04" version="1">MGIFEKGATTDINSAIQRIMNKAAQQNWDTVTATLASPVDALVTELGPLTGKAGKESTVDAAVMLACVTAQNDQSFLTTVSQIATNLSGATVISGNGSVDSALSLTFNIENFRGAVKENVDAVKGSVITTAPVLVQLLDVILIQSVSAVPYVGPVLSGLLGGFGTGLAAAFTVGGNAIASQFTPPDKTDNPVNAITGIQNSSQGMGYTTATNMNKGISGVISKNATLNVGGMVGKAGSKASGPASFIYYLYKGKSAKDESKRLEQLRGLGDDNAILQSLGNTMVQNPLDQHQLAQNARVQQSRFGGAIPQLVQDAGKNLKDKLQTEEDSLTAFFNKIPDVFDSYKKFVLQVANASLVESFAPMIQSFDSRLAEMRIKLSDPTLGPRWLNTPKYREEHVVTLLILGYYFNRLLKSSEPLRKTYRRHIAVYYRHMPMPGTGSQTTFMLPQDSSVVIPQGQDVVPKFSAFSNVSKNETSSAIISAFNATKSLPQLSLSETAVEWAQIGEKAKTYVSLVKNALVNEMAQGFSQSLNNRVGLSSAVKLYLAATLIVNQVMVQTSAGKGIEIDDRYVASLSDLGFVNLYRKLGSYDKADKLKLTGSGPNAKLRYPMASRLSRSASTAERTMMYLFACCVLAYVDVGRIVMGYQDWTKTQERLHLLIDEINKAEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB75</accession>
    <name>A8IB75_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171598.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3074"/>
    <dbReference type="EnsemblBacteria" id="BAF89072">
        <property type="protein sequence ID" value="BAF89072"/>
        <property type="gene ID" value="AZC_3074"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3074"/>
    <dbReference type="eggNOG" id="COG0511">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_016733_3_1_5"/>
    <dbReference type="OMA" id="TAYWAPE"/>
    <dbReference type="OrthoDB" id="1938042at2"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="82"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="158" mass="16431" checksum="2C6AC0A519F1BA19" modified="2007-12-04" version="1">MKNSKTPIDTDVIREIANLLSGSDLTEIEVEADNLRIRVARTPAPVTVAAAAPVAVAPAAAPLATVAAVALEPTSADFSKHPGVVTSPMVGTAYRSPEPGAPSFVEVGTQVREGQTLLIVEAMKTMNAIPAPRAGTVTRILVENGRPVEYGEPLLVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBI4</accession>
    <name>A8IBI4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Biotin carboxylase</fullName>
            <ecNumber evidence="9">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 9">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ordered locus">AZC_3075</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171599.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3075"/>
    <dbReference type="EnsemblBacteria" id="BAF89073">
        <property type="protein sequence ID" value="BAF89073"/>
        <property type="gene ID" value="AZC_3075"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3075"/>
    <dbReference type="eggNOG" id="COG0439">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000395_3_2_5"/>
    <dbReference type="OMA" id="ITHFHTP"/>
    <dbReference type="OrthoDB" id="361205at2"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0092">Biotin</keyword>
    <keyword evidence="9" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="11">
        <location>
            <begin position="1"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="120"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF89073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="448" mass="49117" checksum="07A3D79FD7139B15" modified="2007-12-04" version="1">MFEKILIANRGEIALRILRACKELGIATVAVHSTADADAMHVRLADESVCIGPPQARESYLNIPSLLAACEITGADAVHPGYGFLAENARFAEILADHKVHFIGPKPEHIRIMGDKIEAKKTAQKLGIPVVPGSDGGINSDEEAHRVAAEIGFPVLVKAAAGGGGRGMKVAMTADDLSQALSTARTEAKAAFGDDAVYLEKYLVTPRHIEIQVLGDGKGNAVHLGERDCSLQRRHQKVWEEAPSPALEAAQRQEIGETVAKAMRELKYLGVGTVEFLYENGRFYFIEMNTRIQVEHPVTEEITGIDLINEQIRVAAGLPMTLTQDDVKITGHAIECRINAEHPTTFRPSPGKITHYHVPGGLGIRVDSNAYQGYSIPPHYDSLVGKLIVHGSNREECLRRLRRALDEFVVDGIETTLPLFRTLVRTKDIQDGQYDIHWLEHFLAKGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBL1</accession>
    <name>A8IBL1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ntrB</name>
        <name evidence="5" type="ordered locus">AZC_3087</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171611.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3087"/>
    <dbReference type="EnsemblBacteria" id="BAF89085">
        <property type="protein sequence ID" value="BAF89085"/>
        <property type="gene ID" value="AZC_3087"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3087"/>
    <dbReference type="eggNOG" id="COG3852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_114_39_5"/>
    <dbReference type="OMA" id="EIMLTTA"/>
    <dbReference type="OrthoDB" id="1755994at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="147"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="374" mass="41254" checksum="0835A007E1C2F2C6" modified="2007-12-04" version="1">MKAELKPRTSDGEALTRAILDAVPHPVVTLAEDGRILDANVAAETFFQVSVPLLRRRPFAEFVPFGTPLLSLIEQVRERGSSVNEYRVDLGTPRNGGERIVDIHVAPMAERPGHVVVMFQERTIAEKMDRQLTHRGAARSVSALASMLAHEIKNPLSGIRGAAQLLEQSAGDEDRALTRLICDEADRIVKLVDRMEVFSDERPVEREPVNIHAVLEHVRTLASSGFARHIRFIEDYDPSLPPVYANRDQLIQVFLNLVKNAAEAIDSETDGEIHLTTAFRPGVRLTVPGASSKVSLPLEFCVRDNGKGVPEDLVQHLFDPFVTTKPTGSGLGLALVAKIIGDHGGIVECDSQPRRTTFRVLLPMYRSSRSSEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8IBZ8</accession>
    <name>A8IBZ8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="10" key="2">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF89153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="566" mass="58935" checksum="7179F86ACA378002" modified="2007-12-04" version="1">MVKYSNLPMTAKVVTLLAALGVTSLAGGLYAASGMSDIQTTYVDLINGHQTAILRVARAARSAQTVRAEIYRAIVATTESEDQKAKAALDGGIKRYDTLLAEAAQAAPSKTGEIQQMRNALPAVVSGPCSGAINAGAEQVTVESIERASKLMSTVCDPAIDQIVNTTVSFNDGLIKETAAIKEETARRTSTTIWTTLGCILGATLLIIALAIFVVRGGIVAPLRRLMDKMVAMGEGKLAGEVEGTARKDEIGAMGRTLELMRVQLGEAEVARQEQAQRQEVERKTLERREHLAQGFVARMKDLASGFANSSQEVAESARNLSAAADQTSQQAQSVAAAAEEAATNVQTVAASSEELAASVREINGQVSHSAVVAERAYKEAESSNQRIADLAKAAADIGDVINLIKGIADQTNLLALNATIEAARAGEAGKGFAVVATEVKELASQTSKATADIYTKVTEIQTATQGTVASMSEIIRVITEVKQISSSIAGAVEQQGAATGEIAQNCQQAATGTQDVTNNISGVGQAAQTTGAASSQLLALSQGLSSQATDLRSVVEGFVRDLNAA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724374" evidence="1">
        <location>
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            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="87"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
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        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89169.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="359" mass="38222" checksum="1DCB3EDDBD2F01F4" modified="2007-12-04" version="1">MTGMLARFVRAAFAALLLIGAALAAVPAGAAPLVIRVGYAGIGPGGSKFVPGLAGVISGGRYLEQAFADTPDVTVEWFFFKGAGPAVNEALASGQLDFAFIGDLPSLTARAGGLKTKILMATNARDNLYLVAPAASSISRLEDVKGKRVAQFRGTSTHLTTERVLTEAGIARADIQFFNMDDATALAAIASGDVGAAFGKAIFLTLVEQKLAKVVYTTKGDPSTVTSSHLLVREDFETAHPDLVGRVVTASVKAAAWASDEANRETLFELWAKSGTPIGVFRADYEGQRLDYRLSPLLDALLIETYRYKAAQVKQLGLVRRDVDLDGWFAPKYLHAALKELGLQNRWVRYGADGKPLGS</sequence>
</entry>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="608" mass="67757" checksum="2CBCD1A3A1F53331" modified="2007-12-04" version="1">MNALHPSLCACGSGLRALRCCQLEASALGPAAASRHLLPLVDEAIACHAKGAYGEAERLCLEVLELAPGQGGALAVLYQIRKMQGAGAAAEALVRRLVMLDPNNVWATQELALLLFGKGDLAEGEIHARNAVRIAPTDPQSHNLMGMIMTEMNRPQVGEFHYRRALDLLGQRQPILLANLAWNLKNQGKMAESRALYEESFALAPTILQTVLGWARMEETDRNFARADELLDQAQALAPGHPSILLHRAVVRGRTKQYDAALAILDRMAQQNPGGGLGTNDLLEKGRLLDKMGRYDEAFAAFAAGKRLNVEQSGVTYMAEHAANLAARLKAYFTSNRLRIVPRAKPVESGPRPLFILGFPRSGTTMVEQTLSAHPKVSAGDELSFVHDIANLMPRMLNSPLAYPEALADLWMGDQCEGLDNLRDYYLQRVKQLGVMEPGATRFTDKMPLNETHMGLIALMFPDAPLIHVLRHPLDIVLSVYSNHLTHGFYCANALETIAQHYVLVMDLVEHYRREMALKYLAVRYEDIVDDQETHVRRMLAFADLPFDKRCLKFHENKRYARTASYAQVTEKLYDDSRFRYRHYLKHLAPVIPVLEPVIARLGYSIDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICP0</accession>
    <name>A8ICP0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative outer membrane autotransporter barrel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3234</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3234"/>
    <dbReference type="EnsemblBacteria" id="BAF89232">
        <property type="protein sequence ID" value="BAF89232"/>
        <property type="gene ID" value="AZC_3234"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3234"/>
    <dbReference type="eggNOG" id="COG4625">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000254_0_0_5"/>
    <dbReference type="OMA" id="GSINWDY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005546">
        <property type="entry name" value="Autotransporte_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00869">
        <property type="entry name" value="Autotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51208">
        <property type="entry name" value="AUTOTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Autotransporter" evidence="3">
        <location>
            <begin position="3077"/>
            <end position="3353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1776"/>
            <end position="1833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2025"/>
            <end position="2052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1776"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2028"/>
            <end position="2052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="3353" mass="304987" checksum="327BE8A4629427C4" modified="2007-12-04" version="1">MRSDDSNLWRCVSHAGAPDLAGRYVITDVEESGKIPVFLVSDRGTGMVRPTLFSRKTRKVPGPLALSLPVLLSSVALCALTVPAAAQTSNATIGPSYVYNPSVSGTPGQGGYGCPINNLVSNVSGGGQGGTGTPVSESYVDDLTAPANGGVTYVIAGSTGGAGGVGGGSANSVICTGANSNGASGGQGGNGGMVTITTTGGSGSNTFSSTGIYVYSAGGIGGAGGSTDTDNGQGGGGGIGGAGGQAQLTNWTPFSTQGSGSVGIAVISLGGNGGVGGGGGPGGRGGNGGAGGDGGSVILTNYAAVEAQKAIVIYAQSVGGYGADGGGGGNGYWIFTGSGSGGAGGYGAGAGTVSVTNSGALTSGGLGSRGIEAQSVGGAGGDAGVSQGLNAIGANGGPAGNGSTVTIINSGTITLTNASAVGIAAQSIGGGGGSGGLAFSSGVAGVLIGGSEAGGNGGGGGYASTVSVANSGNICTGNSCNSGVAPTSSAGGAFGIQAQSIGGGGGNGGFGVATSISGTDFAVGGAGGTGGAGGNVFVTNTGSISTQEINSAAILAQSIGGGGGSAGGAVSMDLTTAASISHGGSGGSGGSANAVTVNCTSGDSGANYGAACTTNGALMLSSFNRGTITTNGTGSAGIVAQSLGGGGGHGGYSVSLSTDAYAGAAFSLAVGGSGGTGGDGGNVFAGTGGVGITTYGTDSPGVVAQSIGGGGGNAGASIASSISAAASVALALGTTGGSGGYGSTAAAVNQGSTITTSGDRSPGLLAQSIGGGGGNGGAAISASASTGVGVSLALGGTGGDGGTGGWAYAYNGTNSGPAGPTDITTYGYQSSAIAVQSIGGGGGNGGYTTSLTLSLGPGLGASIGGLGGSGNHSNTVFIENAAGTLTASGGGAAIILGQSIGGGGGNGGFAASGNASLGGAATLAVGGSGGAGSSANTVSITNYGAIVSQATAVETTFQTVPTTTYVPQTTTTYEEEWVCNEYCSWGRVPVTTTTQVPVTTYSTVPTTQTVVSGASIYGNAPGILGQSIGGGGGSGGFAVGGSVSGAGTASLEVGGSGGSGGTGAAVTIDNYNSITLIGSLSSGIVAQSLGGAGGTGGFVVAAGLSSGASATTTIGGGGGSGGTSGAVTINHGNGAITTNGDQSPAIIAQSIGGAGGSGGWDIAGSLASAGAASVGLGGSGGGGGTSGAVTVTADGALATNGLISAGVLAQSIGGSGGNGGFSAGAAGAIVFASDVILGGGGGTSGSAGNVTVTANDAITTLFSQSPGILAQSIGGSGGTGGFAIAGSGATGGGDAKVSVGGAGATGGGGGSGQAAGSVTVIAADITTNGYLSAGILAQSIGGAGGNGGSSRAFSLSGASDSTDGAAASVAIGGGGSSGGDGSSVSVTQTGTIWTGSSGVFSDQSPGILAQSIGGSGGNGGSADANAASTTASVALAIGASGANGGSGGNVSVSSNQNGGGGITTTGLHSSAIFAQSVGGGGGNGGWTQATASSNNYAAGIAIGGSGQGGGSAGTVNVTSGGALATSGALSYGIFAQSIGGGGGNGGAASSTTDAGQGQELQGGVTSVAGAGAGQTASNVSSALSGTSGTGPDNGNGNAANGIAVAVTLAGFAGQGGAGSAVNVTSSSAITTAGDQSTAIFAQSVGGGGGSGGSSSANSSGSSYAASFTLGGGAGPGGAGGDVTVGSTGFILTTGLQAAGIFAQSVGGGGGLGGSSSSTASSGGQAAVSMSLGGSGGNGGDGGIITVNSGGTSTYINTLGPNAAGIFAQSVGGGGGSGGSSSAAASAPGSSSSGGSASSATGSLSGSATGSSTASAAGENGGKPGAQSGSDGGYSLAMSLGGSGGQSGNGNTVTVTNTYGIFTGFSLASGIRSVVPADNSPAIFAQSVGGGGGNGGSSTTNSSAGEYSASLSLGGNGMAGGTGGTVTVTTIGTLQTTGANSAGVFAQSVGNGGGNGGSSTTTSSSSGAVSLALGIGGSSSGGGEGGTVNVTVNAPVTFQGRSGISTQGFNSYGVFAQSVGGGGGNGGAVATASTASSGSSGGSTSTGVQGATTSSSASNAAAVALGLGGTNGAGGAGGQVTVAVAAPVLTSGVQAIAVLGQSVGGGGGTGGASTSNAGDGTYALALGLGGAGGSGGAGGQVTVGSTSAIQTTGAHASGLVAQSIGGGGGIGGASTSGASGGGDVTASLALGGSGGSGGAGGQVTLTFEIPGTGTTLTTSGAHAYGLVAQSVGGGGGMGGSSNGSTSGSGDVNVTLAMGLTGGLGGDGSTVTVTTSNAQASTSGVGAIGLLAQSIGGGGGAGGSSEVMASAANSSGSAAYAGGISLGGSGSGGGAGGDVTVQNAMGITTLGAFAPAVLAQSLSGGGGVASGAASVTGNLASSSLTLSLGGSNGLGANAGTVTVDNYSWVSTSGVDSHGIVAQSIAGGGGLGGSLLSGDGSTAASIQHITTLGAGAESGGGGQVTLQAGSSVQTTGSRAIALIAQSIGGGGGVAGIPTESMSNVSLSGTVTLGGAGGGNGSTVSVSSTTAGSIYTNGSMAHGIVAQSIGGGGGIATMSSDTLILGGSSGGAGGTVTVTTAGQVGTSGTAAIGILAQSIGGGGGVGTSPGSVTFAGKSGDGGSVTVNVNASLTTSGTNAVGVLAQSIGGGGGVAVSDGQSTNWSGPTAASGQGGSVTVNVSAPISTTGAGAYGVIAQSVSGGGGLVMNGTTMELVNGANVLVNGSALISGKAAVYVLTGGSVTASGVGGTGISAQGNGDPIITLAPGTRVTGGPSGTAITSDGTETYITSYGTLSTLDWANGLAIRTSTGFAQIVNGGSLTGNLALTPGAANSVTNLGSGTLWAGSSLDLGGPAGVLTNAGMLRSAFSALGTTTINGALVQTSSGVLAIRADQLSGQSDRFLVTGDARLSGSVRAILDHPARAMPGHFDTPFLSVAGTLSTDSLTVLGDTAILDFSVANIASGLSLGTTINFTPSGLSAHGLTTGALIGEIQTRGSSLLFESIVPTLLQVTTVPGLERSYESVGGGAVSLVPTTTINAASAAMAGITTQMDRWRQGLRPASTALGYAAPERGDDVGGTAASGTGGHYFWGSTIASLTTGSGLSGSTIGGIAGLDGELSGLPALAGAAVSFSSTNISANAYGAVVSNSYGSFSLYGLYQAGPAYMSAVASVGYASSNFDRNLYNLGLNLATDSGLDGWILAGRFEAGYSFALGATGASLTPFIAFQPTQLWLGSGSEMFSLGAGISYQNTAIAALPLYVGFQLDGVWTAPNGQQIAPYLRAAWMHDFSPDRDVPRSFAELPTFSFSGTSIPTVSNAADLHAGLQFLASPTTTLSASFDAQISEGYSTFGATGSFRVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICS5</accession>
    <name>A8ICS5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-lysine 6-monooxygenase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3247</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <comment type="cofactor">
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        <location>
            <begin position="114"/>
            <end position="337"/>
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        <source>
            <dbReference type="EMBL" id="BAF88926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="375" mass="39990" checksum="295DAEEBD6B1D7DD" modified="2007-12-04" version="1">MQPGSHRDGQNRRGSHPLPQHVCVSAPMSTLRTADDLIAAGLAPAAERAVLDAVGARYAVAVTPELVAAMDRTDASDPIARQFVPDVAELRTDPQELVDPIGDDAHSPVPGIVHRYPDRVLLKLVGVCAVYCRFCFRREMVGPGAETALTPDMLERALGYVAAHPEVWEVILTGGDPFMVSPRRMADVVGRLAAIPHVKVVRFHTRVPIAAPERVSEEMVRALKAPGVAAYVAVHVNHARELGDAATAALGRLADAGIPLLSQTVLLKGVNDRVETLDALFRALVERRVKPYYLHHPDLAPGTGHFRLSVPEGQALVRALRGRLSGIAQPTYVLDIPGGAGKVPLTPGYLTPQGAGWHVADNCGGIHAYGEAVPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDJ2</accession>
    <name>A8IDJ2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome c biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2949</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2949"/>
    <dbReference type="EnsemblBacteria" id="BAF88947">
        <property type="protein sequence ID" value="BAF88947"/>
        <property type="gene ID" value="AZC_2949"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2949"/>
    <dbReference type="eggNOG" id="COG0785">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_053225_2_1_5"/>
    <dbReference type="OMA" id="TSLTPCM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="3">
        <location>
            <begin position="39"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="273" mass="28420" checksum="127EAAEEF049D3D5" modified="2007-12-04" version="1">MGRGACRWRAMGPRHGSPPVRRRGVAPKGPMADVSLPAAFLAGLASFLSPCVLPLVPPYLCYIGGATLDDLTNAEPLRQVARRAFYGAVLFVSGFTVVFVLLGAGASAIGNVLRAHLDTLSLIAGIAIILMGLNFLGVFRIAFLSRTARAHVAEPTGVWGAFVMGLAFAFGWTPCLGPVLGAILAVAGSEATVTKGAALLAVYSAGLGVPFLLAALAVRPFLKSLTHMRRFLPVVEKVMGGVLVLTGIAFLSGGIASMSYWLLETFPILSTLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDP5</accession>
    <name>A8IDP5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Thiolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2972</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171496.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2972"/>
    <dbReference type="EnsemblBacteria" id="BAF88970">
        <property type="protein sequence ID" value="BAF88970"/>
        <property type="gene ID" value="AZC_2972"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2972"/>
    <dbReference type="eggNOG" id="COG0183">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031026_1_1_5"/>
    <dbReference type="OMA" id="YAYESHQ"/>
    <dbReference type="OrthoDB" id="330994at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="THIOLASE_1"/>
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    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
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    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="4"/>
            <end position="247"/>
        </location>
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    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="256"/>
            <end position="377"/>
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            <position position="90"/>
        </location>
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    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
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    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
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    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88970.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="378" mass="39352" checksum="B8A00466C574C8F6" modified="2007-12-04" version="1">MSNVVIAGYARSPFAPAKKGDLARVRPDDLAAQVVRELIARTKVNPEDIEDLIVGCAFPEAEQGFNIARLIGMIAELPQSVAGVTVNRFCGSSMQSVHMAAGQILLGAGEAFICAGVESMSRVPMTGFNPMPNPALYAKNAAAYMGMGDTAENVARKWQITRADQEAFAVESQRKAAKAQAEGKLKDEIVPIRINGKSVDADSCIRPETTADDLAGLKPAFDQNGTVTAGTSSPLTDGASAVLVCSEAYAEKHGLEVLARLRSVAVAGCAPEIMGIGPVDATRKALARANIKIEDVDVVELNEAFASQAIACARDLNVKPETLNIDGGAIALGHPLGATGARIVGKAASLLKREGGRYAVATQCIGGGQGIATVLERV</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; thiamine diphosphate biosynthesis.</text>
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        <property type="protein sequence ID" value="BAF89552.1"/>
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    <dbReference type="KEGG" id="azc:AZC_3554"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
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        <property type="project" value="InterPro"/>
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        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
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    </dbReference>
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    </dbReference>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="427"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="40"/>
            <end position="73"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="453" mass="47873" checksum="19E2345505C379B5" modified="2007-12-04" version="1">MALPPPRRDGAMVFLAAEASCGDNDLTAWGAARHARLRSHPSNLSGSCQRREEPMSESLSHHDSASSSAHSARASGARPRVAIVGGGVMGLSIAWRLAEAGCTVEIFEQGRTGLGASHAAAGMLAACAEAEPGEEGLLALNRESQRLWPSFAADLEAASGMAVDLRTDGTIVLALNADDAAKLRHLITFQQGLGLPVEWLNGAEVRRREPHLATKLAGAVWCPEDHQVDNRKVSAALRVAALKAGATLHEDMPVERVEVVDGRARAVIAKGERFGADIVVLAAGAWSRGVAITPATPLPVRPVKGQMLALAMDPAAPILSHVVWAPGTYLVPRKDGRLIVGATVEERGFNADLTAGGQLALLTHAWRALPTIEELPILEQWVGFRPGSRDDAPILGRSAEVEGLVFATGHHRNGILLLPVTAEAISRLILEGETDPVIAPFVAERFLPRAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFB7</accession>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89597"/>
        <property type="gene ID" value="AZC_3599"/>
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    <dbReference type="HOGENOM" id="CLU_2713673_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
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        <source>
            <dbReference type="EMBL" id="BAF89597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="72" mass="7987" checksum="2932D76EB382AFB9" modified="2007-12-04" version="1">MFAFPFTLKTVSSITSGLQKMIADLDALTAEREAMATAKEREAADLITSAHEDREEAMKARRVADKINELVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFM5</accession>
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            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
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    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
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            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
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        <text evidence="2 7 8">Belongs to the GPI family.</text>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:carbohydrate derivative binding"/>
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        <property type="project" value="InterPro"/>
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        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="G6P_Isomerase_C"/>
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        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
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    </dbReference>
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    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
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            <position position="393"/>
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        <location>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00022432"/>
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            <dbReference type="ARBA" id="ARBA00023152"/>
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            <dbReference type="ARBA" id="ARBA00023235"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU000612"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF89629.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="560" mass="59741" checksum="5FA5E38DB5E915C6" modified="2007-12-04" version="1">MTDVTTEIADPQARAEAVSAAWERLAALRAATSDTPIARLFDAPNRFEHFSLSLGDLLLDASKTSLTEEALAGLYALMRAAGVEARRDAMFAGAHINITEDRAVLHTALRDTTAAPLLVDGQDVKPEIRETLGRLAAFAEGVRKGTIAGARGQAFTDVVNIGIGGSDLGPVMATLALAPYHDGPRLHFVSNVDGAHIHDVLKPLNPATTLIIIASKTFTTIETMTNARTARAWIADAQGEAAVGAHFAAVSTALDKVAAFGIDTARAFGFWDWVGGRYSVWSAVGLPLMVAIGPALFADFLAGGAAIDEHFRNAPLEENLPALLAAVGLWHRNVCGYPTRAVIPYDQRLARLPAYLQQLDMESNGKSVTLDGTPVARPTGPVVWGEPGTNSQHAFFQLIHQGTDIIPVEFLIAAQGHEPKLRHQHDLLIANCLAQSEALLRGRSLEAATAQLRAKGMGEAEAQRIAPHRVFSGSRPSLTLAYTLLDPFTLGRLIALYEHRVFIEAAVWGIDAFDQWGVELGKELATDFLPAVTEGAVPPGTSGSTRGTLSHLRNLAADAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFT9</accession>
    <name>A8IFT9_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3650</name>
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    <organism evidence="3 4">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
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    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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    <sequence length="145" mass="16031" checksum="44BC10532E37FD3C" modified="2007-12-04" version="1">MPEHVTIVMIEDDPGHARLIEKNIRRAGVLNEIMPFTDGTSAISFLFGPDGTGAVNAGRALLILLDLNLPDTTGVNILKRIKENEHLKRSPVVVLTTTDDKVEIQRCYDLGANVYVTKPVNYENFSNAVRQLGLFFSVIQVPEAK</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF89344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="ABC_TM1"/>
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    <proteinExistence type="inferred from homology"/>
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        <location>
            <begin position="12"/>
            <end position="40"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="93"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="233"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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        <location>
            <begin position="70"/>
            <end position="261"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
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        <source>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="280" mass="30791" checksum="615B3C845F04CA57" modified="2007-12-04" version="1">MIRDTTLGAKLWITAVWAVIGFFILNLLAMIAAVVVSSFATRWLGTWMPLGWTTRWYTSAWDEFQLNDVLIVTFQVVFLVVFLSGLIGVPAAYAMARRDFPGKKVVMLLFLLPLLVPPITFGIPLATVLYRAGLAGSMTGVVLANLVPTVPFVVLVMIPFVEQIDQRIEAAARVFGANTFKLFRHVLVPLLLPGILAALLLVLVRTIAMFELTFLTAGPTSQTLVVALYYAVFASGVRAVQSIDAMAVVYMITTLIWLLIALRFVNPTQIVARAKSEHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_3364"/>
    <dbReference type="EnsemblBacteria" id="BAF89362">
        <property type="protein sequence ID" value="BAF89362"/>
        <property type="gene ID" value="AZC_3364"/>
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    <dbReference type="KEGG" id="azc:AZC_3364"/>
    <dbReference type="eggNOG" id="COG1573">
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    <dbReference type="HOGENOM" id="CLU_075800_0_0_5"/>
    <dbReference type="OMA" id="GFCYPGK"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
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    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="UDG"/>
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        <property type="entry name" value="SSF52141"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="53"/>
            <end position="221"/>
        </location>
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    <evidence type="ECO:0000259" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="232" mass="25932" checksum="349072DBBCEBB588" modified="2007-12-04" version="1">MTDQLERPNLEAELEERGAVDPPLADLLADIRACRRCVEAPLGRPMPHEPRPVLRASSTARILIASQAPGTKVHLTGLTFHDASGDRLRQWMGVSRAVFYDTAQIAIVPMGFCFPGQDANGGDLPPRRECRATWHDRLFAALPAFDLILAIGRPAQLYHLKRLGREAQIGDSLTQTVANWRQVRAAAERPRVYALPHPSWRNTGWLKRNPWFEQDLLPELRADIAQALARSG</sequence>
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    <accession>A8IIE7</accession>
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        <name evidence="6" type="ordered locus">AZC_3397</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF89395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_3397"/>
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        <property type="protein sequence ID" value="BAF89395"/>
        <property type="gene ID" value="AZC_3397"/>
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    <dbReference type="KEGG" id="azc:AZC_3397"/>
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    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="entry name" value="AAA+_ATPase"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <property type="entry name" value="ABC_transporter-like_CS"/>
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        <property type="entry name" value="CP_lyase_PhnK"/>
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        <property type="entry name" value="P-loop_NTPase"/>
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        <property type="entry name" value="ABC_tran"/>
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        <property type="entry name" value="CP_lyase_PhnK"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="AAA"/>
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        <property type="entry name" value="SSF52540"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="8"/>
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        <location>
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            <end position="47"/>
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        <ligand>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
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    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
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    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89395.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="259" mass="28434" checksum="BCB9EFE06C447928" modified="2007-12-04" version="1">MTDDAPLLVAEGLTRYYGARLGCRDVSLTLHPGEVLAIVGESGSGKSTLLGLLSTELEPSAGHVSYRMRDGTLRDLASLTEGERRLLLRTDWGFVRQHAEKGLRMAVSAGGNVGERLMAVGWRNYAGIRDEAIDWLSRVEIQPDRIDDDPRAFSGGMRQRLQIARNLVTKPRLVFMDEPTGGLDVSVQARLLDLIRSLVADLGLAVVIVTHDLAVARLLSHRIMVMKEGRVIEEGLTDQVLDDPREPYTQLLVSSVLAA</sequence>
</entry>
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    <reference evidence="20 21" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="21" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20 21" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <reaction evidence="1">
            <text>formate + NAD(+) = CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:15985"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.17.1.9"/>
        </reaction>
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        <cofactor evidence="2">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
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            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
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        </cofactor>
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    <comment type="cofactor">
        <cofactor evidence="4">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
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        <text evidence="6">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
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        <text evidence="5">In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="2"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="8 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12 14" id="KW-0408">Iron</keyword>
    <keyword evidence="13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
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        <location>
            <begin position="18"/>
            <end position="96"/>
        </location>
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            <end position="135"/>
        </location>
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            <end position="189"/>
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            <begin position="202"/>
            <end position="230"/>
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            <begin position="237"/>
            <end position="293"/>
        </location>
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            <begin position="918"/>
            <end position="945"/>
        </location>
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        <location>
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        <ligand>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIZ7</accession>
    <name>A8IIZ7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glyoxalase II</fullName>
            <shortName evidence="5">Glx II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gloB</name>
        <name evidence="7" type="ordered locus">AZC_0224</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168755.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0224"/>
    <dbReference type="EnsemblBacteria" id="BAF86222">
        <property type="protein sequence ID" value="BAF86222"/>
        <property type="gene ID" value="AZC_0224"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0224"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_4_1_5"/>
    <dbReference type="OMA" id="NYIWLLQ"/>
    <dbReference type="OrthoDB" id="733552at2"/>
    <dbReference type="UniPathway" id="UPA00619">
        <property type="reaction ID" value="UER00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="6">
        <location>
            <begin position="13"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="257" mass="27572" checksum="9F35537501C80EAE" modified="2007-12-04" version="1">MPLDIRVIPCLSDNYAVLLHDPLTEATAVVDAPEPGPIMDALELEGWDLTHILITHHHADHVDGVLALKAQYGATVVGPKAEAATIPALDVEVVDADPVGLGSAIGRVIETPGHTAGHISFVFPEEKLLFAGDTLFVMGCGRALECDPPVLWHSLQRLRTLPDDFSLYCGHEYTVANGRFALSVDPDNGALRARVADAEAARREGKPTIPALLGDERLTNPFLRADDPDMAERLGLAGADPAAVFTELRARKNVFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJQ7</accession>
    <name>A8IJQ7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome hibernation promoting factor</fullName>
            <shortName evidence="2">HPF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpf</name>
        <name evidence="4" type="ordered locus">AZC_0343</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with 100S ribosomes.</text>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF86341">
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    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
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    </dbReference>
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        <property type="entry name" value="yfiA"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
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    <feature type="domain" description="Ribosom_S30AE_C" evidence="3">
        <location>
            <begin position="133"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00839"/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86341.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <sequence length="198" mass="21866" checksum="31837B47DDCF7670" modified="2007-12-04" version="1">MALRVSGKNMDVGEALRQRFSDRVSEVVGKYFDGGWSGHATVCREGSGYRSELLLHLDSGTNLQAHGNAQEPNACADAAMEKIEKRLRRYKQRLKGRHPQPVNGVDSYLAQSYVLDISPLEEAEEEDIEGWSPTVVAEHPTRLKTLSVRDAVVELEVTGAPVVVFRHAGHGRVSVVYRRADGHVGWIDPSAISPEESH</sequence>
</entry>
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        <name evidence="1" type="ordered locus">AZC_3891</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89889.1"/>
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    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF89889">
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        <property type="gene ID" value="AZC_3891"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3891"/>
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    <dbReference type="CDD" id="cd06357">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039570">
        <property type="entry name" value="AmiC_PBP1"/>
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    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
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    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="427" mass="46427" checksum="BE02BC8867DC76EE" modified="2007-12-04" version="1">MLPNIASHRSSFPTRALHSQALRLVATAPAAFQPTGVFVFVGIRMAHYRIGVMFSANGPYGVVARTLLNGALLAFAELEAAGGPVTLEPVIVDPHGDNAAYRRFSLDLLGSGIRNVIGCYTSSSRKEVIPCFEKHDGLLWYPSHYEGFESCDNVIYTGASPNQHVLPLAEYLAANVGLRGFCIGSNYIWAWENNRIFREAFGAMSGTVVAERYFPVGDTDFERVAETIVEQKPDFVFNNLIGTSAYAFFRAFHAVCARQGIDRARTLPVASCTLAEPELVEIGREAAEGNLSSSVYFASLQTPANLAFTSAYARMFPDAPIPCADAEASYMAVKLLAGALARAGTDEARAVRAAVAGQRLEAPQGEVRIDPDTFHAWLTPRIARSATDFQFQVLLEAPHPVAPDPYLVQSSPRLSVPMRPPKLRVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKJ3</accession>
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        <submittedName>
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    <gene>
        <name evidence="3" type="primary">abrB</name>
        <name evidence="3" type="ordered locus">AZC_3916</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <dbReference type="STRING" id="438753.AZC_3916"/>
    <dbReference type="EnsemblBacteria" id="BAF89914">
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        <property type="gene ID" value="AZC_3916"/>
    </dbReference>
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    <dbReference type="eggNOG" id="COG2002">
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        <property type="entry name" value="SPOVT_ABRB"/>
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        <location>
            <begin position="1"/>
            <end position="46"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
    <sequence length="72" mass="7945" checksum="972CBE2E7D46FEFD" modified="2007-12-04" version="1">MITSRLTTKAQTTIPQPVRNALQLKEGDEIAYAIEGDHVVIRKAKPTLPTDDPFATFSEWDGEADRKAYGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILM5</accession>
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            <fullName evidence="6">Ribonuclease P protein component</fullName>
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            <shortName evidence="6">RNaseP protein</shortName>
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        <alternativeName>
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        </alternativeName>
    </protein>
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        <name evidence="6" type="primary">rnpA</name>
        <name evidence="8" type="ordered locus">AZC_4054</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RnpA family.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4054"/>
    <dbReference type="EnsemblBacteria" id="BAF90052">
        <property type="protein sequence ID" value="BAF90052"/>
        <property type="gene ID" value="AZC_4054"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4054"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_117179_6_3_5"/>
    <dbReference type="OMA" id="GFTCSKK"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54211"/>
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    </dbReference>
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        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF90052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="136" mass="15168" checksum="3AFDF64E517ED8DA" modified="2007-12-04" version="1">MPAELAVVDRLRKRRDFLAAARAERANVPSFLLQGRDRHDEAEPRLGFTVTKKNGNAVVRNRMRRRLREAARLVMPQLGRSGFDYVLVARGPCLDAPFQTLVRDMERAVSRLHAAKKAKTPTSKTPIAPADGGRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILR0</accession>
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        <submittedName>
            <fullName evidence="2">PTS system Hpr kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4067</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="gene ID" value="AZC_3683"/>
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        <location>
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            <end position="51"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="173" mass="19018" checksum="D3F4A055A60F6DE5" modified="2007-12-04" version="1">MTDANDPPVVPDEEPTVFAATLAPHRSLSKRGFVIVMLIIGGLSFGSGVMFLAMGAWPIFGFFGLDVLLVYWAFKANFRAADAREFIRITPSLVEVRHVPARGKGWEARMNPFWTRVKRQDDEDHGTLALALVSQGRETPVGGFLGPIQKGALADDLTHALSEVKRGVTRTHF</sequence>
</entry>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="438" mass="46946" checksum="055CDB0F16593413" modified="2007-12-04" version="1">MAQAAQPASESQRWVQLICGVVCMAMIANLQYGWTLFVDPIEAKHQWGRAAIQLAFTIFVLTETWLVPVEAWFVDRYGPRVVLMFGAVMIALAWSLNSIASSLFVLYAASVVAGIGAGAVYGTCVGNALKWFPHNRGLAAGVTAAGFGAGAAITVVPIAQMIASHGYETAFLTFGIGQGVVVFVLSFFIRKPPAVMAPPKKVSRLPQSKISYAPRQTLSKPIFWLLYAMFVMVASGGLMAAAQIAPIAHDFKVADVPVTLLGVQMAALTFAISLDRVFDGFGRPFFGWVSDNIGRENTMFIAFAVAAGSLAMLVYQGQNPYVFVIFSALFFGVFGEIYSLFPATCGDTFGSKFAATNAGMLYTAKGTAALLVPLASLIAVRYGWSAVFAIAMTLNIVAAFLAMFVLKPWRSRFLARSAVEAEAEERNAAAWKASEAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8INK1</accession>
    <name>A8INK1_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Cytochrome bd-type quinol oxidase subunit 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_3760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome ubiquinol oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172283.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3760"/>
    <dbReference type="EnsemblBacteria" id="BAF89758">
        <property type="protein sequence ID" value="BAF89758"/>
        <property type="gene ID" value="AZC_3760"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3760"/>
    <dbReference type="eggNOG" id="COG1294">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049294_1_0_5"/>
    <dbReference type="OMA" id="FDFRAKV"/>
    <dbReference type="OrthoDB" id="761975at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003317">
        <property type="entry name" value="Cyt-d_oxidase_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43141">
        <property type="entry name" value="PTHR43141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02322">
        <property type="entry name" value="Cyt_bd_oxida_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000267">
        <property type="entry name" value="Cyt_oxidse_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00203">
        <property type="entry name" value="cydB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="335" mass="36209" checksum="08BAFF138C073A68" modified="2007-12-04" version="1">MGIDLPLIWAVIIGFGLMMYVIMDGFDLGIGILFPFIRDRDDRDVMVNTVAPVWDGNETWLVLGGAGLLAAFPLAYSVLLSALYLPLIFMLAGLIWRGVAFEFRFKADEGHRPFWDHAFAWGSIVATFCQGLALGAFINGFRVENGAYAGGVLDFLSPFSVFTGLGLVVAYALLGCTWLILKTEGPLQTRMIALARPITFALLAVIAGVSLWTPLAHEGVAARWFSLPNLLFFLPVPLLVLAAAYGMIKALARGSHGLPFLLALALLFLGYSGLAISLFPNIIPPAVSIWGAAAPVQSLGFALVGALFIIPFILGYTAWSYYVFRGKVRAGDGYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="49" xmlns="http://uniprot.org/uniprot">
    <accession>A8INK3</accession>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3761</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3761"/>
    <dbReference type="EnsemblBacteria" id="BAF89759">
        <property type="protein sequence ID" value="BAF89759"/>
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        <location>
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            <end position="48"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="gene ID" value="AZC_3776"/>
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        <property type="component" value="Chromosome"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
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        <location>
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        <location>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01321"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89774.1"/>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="393" mass="42772" checksum="EFC4F486E408338C" modified="2007-12-04" version="1">MTAFGNPSRIERLRTRMAQAGIDLIVSFKPENSFYLTGFNPIIYSHPVIALLPREGEAQVLLHALRDDHARASSFVRDIRLYGAWSTKVTMGLHWQAALQSLVTEAGFANAVIGIEEDFLPVSRHRELQGLFPGASFKDVSGLIMSTRLVKDADEIENCRAAARIADVGMDAAVEAVRAGGSERDIALASMAAMNRFWADTFPDKEVCDFGSLEGGAQNGLWTWALAGERMFMNCDNPTQRRPAQGECVSIFIWTIINGIHAENERTVMVGEVPEANRRALTSILEIREELFPLLKPGTPISALFNGTKAGLEARGYGKYLPGRIGHGIGLGAHEHPSLDARTDIPLEPGMIFTLEPNLRMPGIGATQISDTVLITPDGCEFLTQSVGGLITA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89833.1"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_3835"/>
    <dbReference type="EnsemblBacteria" id="BAF89833">
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        <property type="gene ID" value="AZC_3835"/>
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    <dbReference type="InterPro" id="IPR009061">
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        <property type="entry name" value="HTH_17"/>
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            <end position="61"/>
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    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89833.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="93" mass="10143" checksum="C02D2370938F602C" modified="2007-12-04" version="1">MRPDLATLPPRYLRTKEAAEFLSLSARTLEKHRTYGTGPAYRKLGGRVVYSIDDLQAWTDRGAVTSTSDPRGTVLPAKRHALAAGSFAGRAAR</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF86615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_0617"/>
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        <property type="gene ID" value="AZC_0617"/>
    </dbReference>
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    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="CheY-like_superfamily"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Response_reg"/>
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        <location>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF86615.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <sequence length="406" mass="43593" checksum="D0718CD7CE6B7817" modified="2007-12-04" version="1">MPRAQAVLVLDDEPELREDLAELLVGAGFSAEGRGDARSLTDAEFGAFDVVILDLAMPGTDGLSVLGRLAHVPQAPRIIFISGHGEDVLQTAAAVARREHLQVAGVLRKPFTAEDVLRLLGQSWVPLDSGASIAWSDADIRSALAEAIDERALSVAFQPKVTAKGLIFAGAEALLTGDLPRLGYVSPEIIVRAATREPELIGAMSLEVLRCSAAACRAWIDAGWDVPVSVNLPFEVLCLPDISERLLSPIHEEGLMPRHVIFELTEDAIYDSSSDVLAILARLRLAGFGLSLDDVGRRQSGLLQLANLPITEVKIDLQLLAQARTWSKSRSVFVSVAELGHRLGLTVVAEGVETRDDLVLVRSLPVDYVQGYLVSRKQHLPDLLAMLAASSSRGAPFAPDHVVPIS</sequence>
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    <accession>A8IPM7</accession>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
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            <dbReference type="EMBL" id="BAF86652.1"/>
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    </evidence>
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        <source>
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</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169225.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0694"/>
    <dbReference type="EnsemblBacteria" id="BAF86692">
        <property type="protein sequence ID" value="BAF86692"/>
        <property type="gene ID" value="AZC_0694"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0694"/>
    <dbReference type="eggNOG" id="COG3683">
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    </dbReference>
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    <dbReference type="OMA" id="YGAMFAN"/>
    <dbReference type="OrthoDB" id="1698942at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010412">
        <property type="entry name" value="DUF1007"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06226">
        <property type="entry name" value="DUF1007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
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        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724595" evidence="1">
        <location>
            <begin position="24"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="211" mass="23371" checksum="D4391FB5C40DB107" modified="2007-12-04" version="1">MRQRFAFLLAAALSCLGAGVAEAHPHVWVTMRTTILFDPQGNFVGLRNDWTFDEAFTAFALQGFPKDANGNYAKETLAPLAEVNVTSLKEYDYFAHGKTAKAKMAFKDPVDYSLTFDKDLLTLHFTLPVAKPVPSKGSLTFELYDPTYFVSFDFEEKDPVRLEGAPAGCTFSVVTPSQPQTMQVDESFFTNLTSSSTYGAQYADKILVKCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPX8</accession>
    <name>A8IPX8_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2">DNA helicase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ordered locus">AZC_0714</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Oyaizu H."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="246" mass="26539" checksum="F1ED6106A158D12C" modified="2007-12-04" version="1">MMRSPAPGAATAVVLDVTDMGRRLRRRQSRPTTVDGSAGDPDSDRCRSKAGDSERSLHPSVPRRHFAEQLRAPGIDLRKGGQHEQGLCTRSRRPDVGRRLLLSVGYAGRAADDRHRAGARFGPHRSTAHRASLPREEMIMGRSLLILVPLLAILGLSLWWMTSTWQAAADAPFAGGDYVPLVLGVILSVVIGCGLMALLFISSRRGYDEAAQTQVLPRPPSPEVPPPVRDENAPRAGGATRPNGSP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2009-12-15" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQ90</accession>
    <name>ACCD_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="1">ACCase subunit beta</shortName>
            <shortName evidence="1">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="1">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">accD</name>
        <name type="ordered locus">AZC_1024</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AccD/PCCB family.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169555.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HQ90"/>
    <dbReference type="SMR" id="A8HQ90"/>
    <dbReference type="STRING" id="438753.AZC_1024"/>
    <dbReference type="EnsemblBacteria" id="BAF87022">
        <property type="protein sequence ID" value="BAF87022"/>
        <property type="gene ID" value="AZC_1024"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1024"/>
    <dbReference type="eggNOG" id="COG0777">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015486_1_0_5"/>
    <dbReference type="OMA" id="PEGLWIK"/>
    <dbReference type="OrthoDB" id="504557at2"/>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword id="KW-0276">Fatty acid metabolism</keyword>
    <keyword id="KW-0444">Lipid biosynthesis</keyword>
    <keyword id="KW-0443">Lipid metabolism</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <feature type="chain" id="PRO_0000389667" description="Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta">
        <location>
            <begin position="1"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="2">
        <location>
            <begin position="25"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01136"/>
        </source>
    </evidence>
    <sequence length="297" mass="32660" checksum="3E20B38C27AA9B96" modified="2007-12-04" version="1">MNWISNVVRPKIRSFLNRRDVPENLWVKCPETGQMVFHKDLEANQYVIPGSGFHMRMGPADRLKATFDDGAYEEVALPDVPIDPLKFRDERRYIDRLKDARAKTGAQDAVKVAHGLLEGLPVTVAVQDFGFMGGSLGMAAGEAVVTGLFTAAEKKTPFIMFAASGGARMQEGILSLMQMPRTTVAIQELREARLPYIVVLTNPTTGGVTASYAMLGDVQIAEPGALIGFAGPRVIEQTIREKLPDGFQRSEYLFEHGMIDMVVHRHQMRETLARVCRLMMKAPGVPPKGRLPAPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQZ8</accession>
    <name>A8HQZ8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169612.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1081"/>
    <dbReference type="EnsemblBacteria" id="BAF87079">
        <property type="protein sequence ID" value="BAF87079"/>
        <property type="gene ID" value="AZC_1081"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1081"/>
    <dbReference type="eggNOG" id="COG5400">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_077638_1_0_5"/>
    <dbReference type="OMA" id="WGLPNGY"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008325">
        <property type="entry name" value="EipA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06577">
        <property type="entry name" value="EipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033924">
        <property type="entry name" value="UCP033924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723811" evidence="2">
        <location>
            <begin position="28"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="221" mass="23640" checksum="229DAE241E919E90" modified="2007-12-04" version="1">MTTPRSSLARTLAGLAFLAALASPAAAQQQPYGSQPYTAPPQPQPYQPQQQYQPRQGQGQNSTYSTNELVAKGHSFFGTVSKGLALSIEKAVSQWGQPNGYILGQEGTGAFVGGLRYGEGTLYTRNAGDLKVYWQGPSIGWDFGGDGGRTMILVYNLRTVDDVFRRFGGVTGSAYFVAGFGMTALTADDIVVVPIRSGVGVRLGANLGYLKFTPQPTWNPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRA4</accession>
    <name>A8HRA4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Selenocysteine-specific elongation factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">SelB translation factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1153</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1153"/>
    <dbReference type="EnsemblBacteria" id="BAF87151">
        <property type="protein sequence ID" value="BAF87151"/>
        <property type="gene ID" value="AZC_1153"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1153"/>
    <dbReference type="eggNOG" id="COG3276">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_023030_3_0_5"/>
    <dbReference type="OMA" id="YAIDRVF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015190">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015191">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004535">
        <property type="entry name" value="Transl_elong_SelB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09106">
        <property type="entry name" value="SelB-wing_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09107">
        <property type="entry name" value="SelB-wing_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00475">
        <property type="entry name" value="selB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="638"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="701" mass="74810" checksum="A9BF6ED356A4C5F9" modified="2007-12-04" version="1">MIIGTAGHIDHGKTSLVRAITGVDTDRLKEEKARGISIDLGFAYMPAGDGAVLGFIDVPGHEKFVHTMLAGAGGIDFVVLVVAADDGVMPQTREHLAIIDLLGVRHGLVALTKADLVDADRLAAVTAEIAATLDGTVLAGAEILPVSTVTGAGVADIRARLEAANARLARRAAEGRFRLAVDRAFTLSGTGTVVTGTVLSGEVRVGDRVMLSPSGRPARVRSIRAQDRASDIGRAGDRCGINIAGDGLSKDDLSRGDVLLADTLHAPADHIDARLRVLPGEPKPVGQWFPVRLHHAAREVGARIVLLEEAVKPGETGLVQLVLDAPIAAAAGDRFVIRDTSAQRTIGGGVFLDLRGPARKRRTPERLAQLGAIAEPDAAVALAHLLDLPPFHLDLATFARDRALASDAVPALIRDLDLKALSVGDTAVVLSGARWATFHERLLGTLDTFHADNPDLPGIGIERLRMQAEPRLPAPAFKAALQALAQAREIALDGAWVRRAGFEVRLTPLDEANWARVAPLLAGEERFRPPRVRDIAGLIEVPEAEIRRLMKLLGRLARVDEVAHDHFFLRATVGEMVGIIARLSAAHGNFTAAQFRDEVENGRKVAIQILEFFDRHGVTLRRGDLRRINPHRLDLFRTSSDDAPADNSPAAPDAVAAHGGEASLVGRPDFKSGRGREPVLGGFDSHSLPPLSPTPPKEKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRH8</accession>
    <name>A8HRH8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fkbM</name>
        <name evidence="2" type="ordered locus">AZC_1190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87188.1"/>
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    <dbReference type="EnsemblBacteria" id="BAF87188">
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    </dbReference>
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    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
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    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="51"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87188.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="283" mass="30524" checksum="0EDC62EE20736526" modified="2007-12-04" version="1">MLEALKAQMEARTPRLFGLVAGLFNRAAARNSAEPANLLPFLVTPGDRACDIGANNGLFTFWMLRLGVQVEAFEPNPRLARVLDLRFAAARRAGRFRLFACALSDGTGPATLHVPRGLSPLASIDGDFVAHSTAPVDHVTIARRTLDDCIEGRVDFLKIDVEGHEAKVLAGASRLLAESRPTLLVEAEERHHAGAVTALEGLLAPLGYEGFFCADGAVQPLARFDPALHQRPGALNAQGTRVQPGATYVNNFVFIARADRKARFMAWRPGPWLARGRGNSAAD</sequence>
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            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
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        </reaction>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="EnsemblBacteria" id="BAF90068">
        <property type="protein sequence ID" value="BAF90068"/>
        <property type="gene ID" value="AZC_4070"/>
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    <dbReference type="eggNOG" id="COG4191">
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    <dbReference type="OMA" id="EILIYVP"/>
    <dbReference type="Proteomes" id="UP000000270">
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        <property type="term" value="C:integral component of membrane"/>
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        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:signal transduction"/>
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        <property type="entry name" value="HAMP_dom"/>
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        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
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        <property type="entry name" value="His_kinase_dom"/>
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        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="BCTRLSENSOR"/>
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        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
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    </dbReference>
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        <property type="entry name" value="HIS_KIN"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="52"/>
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    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="205"/>
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    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="202"/>
            <end position="257"/>
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    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="271"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
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    </evidence>
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        </source>
    </evidence>
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    </evidence>
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        <source>
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        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="495" mass="53849" checksum="87921237296C723B" modified="2007-12-04" version="1">MRTSRMTQADTSTSSPRAAARRVRFGLSAKLLTLTIAFVTIAEIAIFVPTMANFRLAWLSDRLAAARTAALVLDAAPEDTIPGDLTRALLQSVGAKVVVVKRQETRRLLAMSDMPPPIDRHVDMRNTSLWDAVVDAFDTLAAGNGRTLRVVGDAPRDGEFLEIVIPETPLRKAMLRFSATVLAISLVVSVLAGVLVYFSLHWLFVRPMRRLTAQMAEFQAAPEDASRIVVPSGRDDEIGVAEEALAEMQTELAQTLSQKTHLAALGLAVSKINHDLRNLLASAQLMSDRLVDIPDPAVQRFAPKLVAALDRAIAYCQQTLSYGRAQEPLPDRRPVDIAALLTEVRETLGLGPDAPIGWVCAVEKHLAADADPDQLFRVILNIARNAVQALEARAPNTPERDQIRISARRIGSVVEIEMSDTGPGIPAERRDRLFAAFQGSARRGGTGLGLPIADELVRAHGGELRLLEGTIGATFLISLPDRPIELRQRALRARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="69" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4096"/>
    <dbReference type="EnsemblBacteria" id="BAF90094">
        <property type="protein sequence ID" value="BAF90094"/>
        <property type="gene ID" value="AZC_4096"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4096"/>
    <dbReference type="eggNOG" id="COG3706">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_134_2_5"/>
    <dbReference type="OMA" id="QACHVAR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
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    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
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    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="324"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="8">
        <location>
            <begin position="478"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="619" mass="67804" checksum="900696F7386C3FF5" modified="2007-12-04" version="1">MSVIRKARGARHLMAVLYGIAVFLAFGVWSEVTSWNAYRERVSSQLAETARAVGNHVDDVIEVAKQPLGALALDLDRDWATALGGLHFISTMRTLAEQSRFVRSLAFVRADGYLVESTLSPLSPGLNLGHRDYFEHHKTSPSLEPHIGNPAFGPVIRDWFITISRRVNRPDGTFAGVLLATVSIDHFAKFFDGYALGEGRTLLLIGTDGRVLLRLPVEASSSVVSLAQTKFFRERLVVEPFGTAEYTSPFDGERRVGGYFRSAASGITSTVGVATSTLFADWVRQVAMRWAFALMAVMGAVFLGIRWQRQSWMRERSEAETAARVAEFRVIANASSDLIEKLDHAGTREYVSPSARDLLGREPEDLIGHPIFFGYGPEAEADWRAALSRIRGGSSVERLIFSKTAVDGGTIWLESLITKAADTGGMVVVTRNITGQKMLQEKLDAQTKIDELTRVFNKRHFNAALQSLTSAALAPGGRPFSLLIVDVDRFKMFNDTYGHVPGDACLRRIATAIASAVRASQDVVARYGGEEFALLLPDVGPERAADIAEKVRAAVFDLGIEHRANVPWGRVTVSIGCATFDGTILREANELVVLADRALYRAKTEARNAVRVHEPVGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRZ3</accession>
    <name>A8HRZ3_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_4117</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172637.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4117"/>
    <dbReference type="CAZy" id="GH77">
        <property type="family name" value="Glycoside Hydrolase Family 77"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90115">
        <property type="protein sequence ID" value="BAF90115"/>
        <property type="gene ID" value="AZC_4117"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4117"/>
    <dbReference type="eggNOG" id="COG1640">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_022072_1_0_5"/>
    <dbReference type="OMA" id="QYPNWRL"/>
    <dbReference type="OrthoDB" id="814704at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="malQ"/>
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    </dbReference>
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    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="638"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="650"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="686" mass="73209" checksum="D79A7C703406E56E" modified="2007-12-04" version="1">MDDTLHDLARAAGVSPHWHDAFGRPQTVPPHALRAILGALGLPAKTDALARESLDGLRHTAVPTPPLVTGDVGAPLRVPLPGSGPLRWRITLEDGGLVEGESQGGGLDLPALNVPGYHRLEAGGLDVTLAIAPERCSSIADATGDERARLWGLGIQLYGLKRPGDGGIGDFTALSDFVRHAAGTGASATVLSPVHAAFSADPHHFSPYAPSSRLFLNVLHVDPAGLFGTDAVRQAADALALGGILSACESAPLVDWVRAGPARLALLRRLFDTELPARPDLVASYADFRRAQGQALEDHARFEALHAHIWGSDLHRWNWRTWPGEYRDATSPAVAAFAREHGSEVEFHAFLQWAAARGLASAQAAARAAGMPVGLIGDLAVGCDGGGSQCWSAPDDMLIGLSIGAPPDLLNSLGQAWGLAAFSPRALVASGFRSFIAMLRASMAHVGGVRIDHVMGLLRLWMVPDGADPKDGAYLAYPFEDLIRLVALESQRHRTIVTGEDLGTVPDGFRETLARRQILGMQVLWFEREGPRFKTAGEYLPTAMAVTGTHDLPTVAGWWRGRDIDWRAPLGLLGEGIDEPAARAEREADRHALWSTIGDGTPPPAATEPDAAVDAALGFVGRTTAPLVIIPLEDVLGESEQPNLPGTVDDHPNWRRRQPEATAQLLDRPEVKRRVALLDQARQPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8HS20</accession>
    <name>A8HS20_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">ABC transporter nucleotide binding ATPase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4129</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4129"/>
    <dbReference type="EnsemblBacteria" id="BAF90127">
        <property type="protein sequence ID" value="BAF90127"/>
        <property type="gene ID" value="AZC_4129"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4129"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="RFARDVC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="28"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="234" mass="25586" checksum="313B2443D23AFD36" modified="2007-12-04" version="1">MRKRFGDNEVLKGINLDVQAGEVIAIIGKSGSGKSTLLRCINGLESIDSGSILVAGAHLAPDDAHLRALRLKVGMIFQQFNLFPHLTAGRNVMLSPMVVKKVSAAEAEKEARLRLEQVGLGHKFDAYPDELSGGQQQRVAIARALAMQPLALLCDEITSALDPELVNEVLQVVGKLAQEGMTLLMVTHEMRFAREVCDRVVFMHQGRVHEIGPPEEVFSNPQTPELQQFLGMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8HU44</accession>
    <name>A8HU44_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Putative O-methyltransferase</fullName>
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    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0905</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <dbReference type="STRING" id="438753.AZC_0905"/>
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        <property type="gene ID" value="AZC_0905"/>
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    <dbReference type="eggNOG" id="COG4123">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
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    </dbReference>
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        <property type="term" value="P:primary metabolic process"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
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    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="15"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="235" mass="24134" checksum="6D07129D941AC7F2" modified="2007-12-04" version="1">MLTQPRTGHRAGHDALLLAALAPAQARRIVDLGAGVGTAGLAVLVRLREASAHLVELDPATAALARQNAAGNGMSDRCAIVEADVRTLGKPAGPAEPAAQAADLVIANPPFNARAAHQTSPHARRATAHMADGETLMDWVLAAYRCLKPGGQVGLILRPADLATLLDALAGRFGAAELLPVHARADAPAVRLLVRAVKGRRTPPAIRPGLILAEADGRTTATADAVLRGEAGLIP</sequence>
</entry>
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    <accession>A8HUV9</accession>
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        <recommendedName>
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        <name evidence="2" type="ordered locus">AZC_0986</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86984">
        <property type="protein sequence ID" value="BAF86984"/>
        <property type="gene ID" value="AZC_0986"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0986"/>
    <dbReference type="eggNOG" id="COG4995">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_317290_0_0_5"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
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    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="623"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="918" mass="99284" checksum="6BDC0B12BFFEC81A" modified="2007-12-04" version="1">MHRLFGADALQQALAQHAMRWRMSGRLVFLLRVAIGVVALSAGGAALAQTAGGTTQAMKGCERLLAEGKVQEGYPCLRDVLKTIAAGSDDARTLQEYRTWAEAFLQARQPRLAAALYEDALASRAASGKPLADLGRIHFAYSYYVLSRGPDKDKAIAHARAGLDILEKTLGPGAYDTVAARDNLAVLLSDSGAIAPGLNLAESNFDIALKSLGEDEPLTWRVSNNFAEALRSIGRPEAAVPIDQVLLAKRVKHYGEGSIQALVSASNLALSYLEMGDKAQAMRYFRLQGRFGAKLADPTSEHEAQAKAWYTYTDIFFSPDPQLKPDMLEALMGLKDWRSAPDLMRVKASELAAKEYERQGKVRQGLALRQAAYEISASSFSARSPITFDALLGLARAHVRNQEPEKALATFRDLDRQLYDWTLREVGTAGNRFIAETTRVLADNFLYEFGRFALEEPSARPAFADAAGRWKALESGQRARLRQMVDTLPDDVKPLAQEVIRLLGRQQEVLSERRTAAERRDEEALVQDVQKKSGELSVRLAALKLPEPPPLDAAIAGALGPKDALVNFVLITRRQGTRSSDAAIEDQRLLAVVRRHDQPPQVLELGSFPDIVARLKVGQEGTDTAKEMYAALFGKLSGALGGAERLFIVPDAELYGIPFAALRDGEGRFLDQIYEVRLLTREDALPTAVRRDRLAPGGKAVLAGGLDFSSGKQKGPRALPATAREVAEVGKVLTSAGYGTRVLTGTAGTEDALRQAIPGASVVHLATHGFFEPPHDGLSALWRGGIVLARAGDDKPPKANDRDGYLYAEELMGWDLSAADLVVLSACETAVGDRSAVSAIRGLPTALAIAGARRSLLTLWPVADAGAANFMIAFYRHAAEPGATFSSALRQTRLDAIAGKVPQADDPEVWASFVMYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8HV72</accession>
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        <submittedName>
            <fullName evidence="3">Chemotaxis sensory transducer</fullName>
        </submittedName>
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    <gene>
        <name evidence="3" type="ordered locus">AZC_4281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <sequence length="462" mass="49655" checksum="728B0C3B95E214A1" modified="2007-12-04" version="1">MPQARSCVSLLIICVPAGSGAFSERCPEGSSCNSDLLLIQAHGTAATDSRRMTRVLIEGRLASAARRKCKGRHPPCAPARAPCVPPRGIGTPDGDGLSTMHGTFDAALKASLSADTPEKVIDLADHSAAVAAGKARAIQAITGQTRMLALNATIEAARAGDAGRGFAVVAEEVKAVSAEIGRLASDMETELRSALDELRAVGRRMAQDVRGQRLVDLSLNAIEIIDRNLYERTCDVRWWATDAALVNCGDPTPERVAEAERRLGVILSAYTVYLDLWFCTPEGRVVAHGRADRYPNIRGLDVSRESWFREAMDSVSGDDYAVADVNPCPALRGAPVATYAAAVREGGALRGKPIGVLGIHFDWEPQARAVVEGVRLSPDEAERSRVLLVDARGRVIASSDRRGIFTELVNLNARGRTSGIDHTPDSKTIAFHMTPGYETYRGLGWAGVIMQDPLHAGMRHHR</sequence>
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
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    <sequence length="292" mass="31522" checksum="378DD2E9A8F21327" modified="2007-12-04" version="1">MENYTGIKTTMPHASDAARRRALADFVRTRREKLDPAAHGFTDLRRRRTPGLRREEMAQVAGLSATWYSWIEQAREMALSASAVSRLAQALGLSPAERAYLFDLAGREDPHPPAPDAFPPHGALARLVAGMPEPAYVLDGTWTAQVWNAAAADLFRGWLDGAAERNLLRFLFLDPAAVALIPDHAERTRRVLAEFRADTSRHLAEPALAGLVAGLMADSPLFARLWHAQGVLGREGGLRTFCAADGVIRSFEQVTLAALPGGRTKLVMLAPAVADGGLEPVAAPFFGPSESA</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4" key="5">
        <citation type="journal article" date="2009" name="PLoS ONE" volume="4" first="E4695" last="E4695">
            <title>A novel endo-hydrogenase activity recycles hydrogen produced by nitrogen fixation.</title>
            <authorList>
                <person name="Ng G."/>
                <person name="Tom C.G."/>
                <person name="Park A.S."/>
                <person name="Zenad L."/>
                <person name="Ludwig R.A."/>
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            <dbReference type="DOI" id="10.1371/journal.pone.0004695"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="4">ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="4">ORS 571</strain>
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    <reference evidence="3" key="5">
        <citation type="journal article" date="2009" name="PLoS ONE" volume="4" first="E4695" last="E4695">
            <title>A novel endo-hydrogenase activity recycles hydrogen produced by nitrogen fixation.</title>
            <authorList>
                <person name="Ng G."/>
                <person name="Tom C.G."/>
                <person name="Park A.S."/>
                <person name="Zenad L."/>
                <person name="Ludwig R.A."/>
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            <dbReference type="PubMed" id="19277114"/>
            <dbReference type="DOI" id="10.1371/journal.pone.0004695"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
            <strain evidence="4">ORS 571</strain>
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    <reference evidence="4 5" key="7">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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</entry>
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                <person name="Aono T."/>
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                <person name="Wakao S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <dbReference type="STRING" id="438753.AZC_4462"/>
    <dbReference type="EnsemblBacteria" id="BAF90460">
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        <property type="entry name" value="DUF1223"/>
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    <sequence length="319" mass="33854" checksum="3A4EEF226ABE9892" modified="2007-12-04" version="1">MAASARSSRRPRRRNGRLRGLLASHCEVTRPGAARRLCVDWFFTTSRLNPASMTHAFLPHRLLSALLMLACIGFGTQAMAEDAKADAKTNAANASAGTELPKAVVELFTSQGCASCPPADALLGELARDPGVISLTLAVDYWDYVGWKDTLAQHGHTQRQRAYADVRGDRKIYTPQMVVDGTQAAVGSDRLAVEKALMSAKAGGSALMVPVKLSRDGDDLLVDVGALAQAPGAEVWACPVIRSQTVSIGRGENSGRQVTYTNVVRGWVRVGTWDGDPDTFKVPVNQLRFEGANAVVVLVQSGTFAAPGAILGAATTPLN</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
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            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="AP009384">
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        <property type="project" value="UniProtKB-UniPathway"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Aldolase_TIM"/>
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        <property type="entry name" value="PTHR11458"/>
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    <keyword evidence="7 11" id="KW-0456">Lyase</keyword>
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    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
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        <location>
            <position position="216"/>
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        <ligand>
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            <dbReference type="RuleBase" id="RU004161"/>
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    </evidence>
    <sequence length="309" mass="33562" checksum="E656BDBD4F9121A7" modified="2007-12-04" version="1">MREHTLTVDDLIWPIFVVEGEKVRENVASMPGVERLSIDEAVRAAEMAAKLRIPALALFPYTEPGLRDPHGSEALNDNNLVCRALRAIKARVPEIGLITDVALDPYTSHGHDGLMDGERIVNDATVEVLVRQSIVQAQCGADVIAPSDMMDGRVGAIRLGLDKAGFEDVQIMSYAAKYASAFYGPFRDAIGTSKTLIGDKRTYQMDPANGAEAIREAALDVEEGADMLMVKPGLPYLDVVYRLKEAFALPTYAYQVSGEYAMIEGAIRNGWLDGSRVVEESLIAFKRAGADGILTYFAPRVAERLAAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY65</accession>
    <name>A8HY65_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1581</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170109.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1581"/>
    <dbReference type="EnsemblBacteria" id="BAF87579">
        <property type="protein sequence ID" value="BAF87579"/>
        <property type="gene ID" value="AZC_1581"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1581"/>
    <dbReference type="eggNOG" id="COG0671">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_072573_6_0_5"/>
    <dbReference type="OMA" id="DIFEVIT"/>
    <dbReference type="OrthoDB" id="1930882at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="133"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="295" mass="32004" checksum="812F22916E7D021C" modified="2007-12-04" version="1">MSETAATPPQPSLWQEEVRATLHGVGAAWQMLRTRKVRTPLPRVPMDQTVELLCLFLLACGVVAGTLVLVDPLVLGLRARLPLELVRVFERVTDLGLGSVVLIPLGVAFLFLLATLRRFDPLYRRVAAAVVARLGFLILSVTGVSLFVLVVKYALGRARPSLAMTLPGPHPHLTFEFFRLKASYASFPSGHSAVVFSFAVALALLFPKARWWLIGLAVLVATSRVVLGSHYPSDVLASAALSTAFVFFMAKVFAARRLVFAVAADGTIRPKPGPSMRRLLALFSPAHRTNGSKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY68</accession>
    <name>A8HY68_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1582</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170110.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1582"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87580">
        <property type="protein sequence ID" value="BAF87580"/>
        <property type="gene ID" value="AZC_1582"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1582"/>
    <dbReference type="eggNOG" id="COG1216">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033536_11_0_5"/>
    <dbReference type="OMA" id="FCIAGYR"/>
    <dbReference type="OrthoDB" id="1064289at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="15"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="245" mass="27428" checksum="92631D708B1C8E71" modified="2007-12-04" version="1">MTSTLAGDAGTPRLSVVIAVKNEAGNVTPLIEEIDAAFKEPFELIFVNDGSTDTTPQELAAAARTRPYMRVITHANSCGKSAGMDTGARRARGDILIMLDGDGQNNPTYLPQMVRVLDEGGPRVGMVQGERQGRKDTAFKRFQSRTANRVRRALLNDDTRDTGCGLKVVRRHIYVALPMFDGLHRFTPALVKREGYEIRTLPVVDRARWHGVSNYGFWNRLWVGIADLLGVWWLIRRRRVPQVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="54" xmlns="http://uniprot.org/uniprot">
    <accession>A8HY92</accession>
    <name>A8HY92_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170118.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1590"/>
    <dbReference type="EnsemblBacteria" id="BAF87588">
        <property type="protein sequence ID" value="BAF87588"/>
        <property type="gene ID" value="AZC_1590"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1590"/>
    <dbReference type="eggNOG" id="COG2304">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1128360_0_0_5"/>
    <dbReference type="OMA" id="VFMFQEG"/>
    <dbReference type="OrthoDB" id="1605076at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="237" mass="24567" checksum="5B5576AD19F6D5D3" modified="2007-12-04" version="1">MPDDPALPAGAPSAPGEIEAFLRKAGEIAPPRPQAGQGRLAFALDATASRQPTWDLACGLQAEMFSVAAALGGLEVQLVYYRGASECRASGYVSDEARLATLMGRISCAGGRTQIGRVLRHLETEAGRSGLRAAVFVGDALEEPAAGLLEAAGRLGVMGLRLFVFQEGWDASVERVFREMAGLTGGAWCRFDASAPGELATLLKAVAAYAAGGQAALLASPEAGARRLLAAMPRQRG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2010-08-10" modified="2022-08-03" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYF7</accession>
    <name>LON_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lon protease</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lon</name>
        <name type="ordered locus">AZC_1610</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="1">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HYF7"/>
    <dbReference type="SMR" id="A8HYF7"/>
    <dbReference type="STRING" id="438753.AZC_1610"/>
    <dbReference type="MEROPS" id="S16.001"/>
    <dbReference type="PRIDE" id="A8HYF7"/>
    <dbReference type="EnsemblBacteria" id="BAF87608">
        <property type="protein sequence ID" value="BAF87608"/>
        <property type="gene ID" value="AZC_1610"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1610"/>
    <dbReference type="eggNOG" id="COG0466">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004109_4_3_5"/>
    <dbReference type="OMA" id="GAWQVVD"/>
    <dbReference type="BRENDA" id="3.4.21.53">
        <property type="organism ID" value="609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0378">Hydrolase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0645">Protease</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0720">Serine protease</keyword>
    <keyword id="KW-0346">Stress response</keyword>
    <feature type="chain" id="PRO_0000396535" description="Lon protease">
        <location>
            <begin position="1"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="3">
        <location>
            <begin position="68"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="2">
        <location>
            <begin position="647"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="734"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="777"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="412"/>
            <end position="419"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01123"/>
        </source>
    </evidence>
    <sequence length="856" mass="94404" checksum="8AF4119A7EAFCDE3" modified="2007-12-04" version="1">MVNTPVPGLGSCASRGLIAAPASIIRSRPGCDHAGECIVVCVGVFRKDWVMTSPKQRPPLVPGVAQTFPVLPLRDIVVFPHMIVPLFVGREKSIRALEEVMRGDTYILLATQENASDDDPATDAIYRVGTLATVLQLLKLPDGTVKVLVEGVTRAQVVQYTDRADLYEAEAISLPDEVGDVVEAEALARSVVNEFENYVKLNKKVSPEVVGVVGQIEDHAKLADTIASHLAVKIPEKQAVLETVKVADRLEKVLGLMESEISVLQVEKRIRTRVKRQMEKTQREYYLNEQMKAIQKELGDEDGRDDLQELEDRIKRTKLTKEAREKATHELKKLRQMSPMSAEATVVRNYLDWLLSIPWGIKSKVKKDLPFAQSVLDSDHYGLDKVKERIVEYLAVQSRANKLAGPILCLVGPPGVGKTSLGRSIAKATGREFVRVSLGGVRDEAEIRGHRRTYIGSMPGKIIQSMRKAKKSNPLFLLDEIDKMGADFRGDPSAALLEVLDPEQNPTFNDHYLEVDYDLSNVMFVTTANTLNIPPALLDRMEVIRIAGYTEDEKAEISRKHLIPNALQKHGLSAKEWSIDDAALLQVIRRYTREAGVRNLEREISTLARKAVKELVISKKKSVKVTAKNLETFLGVPRFRYGEIEREDQVGVVTGLAWTEVGGELLTIEGVMMPGKGRMTVTGNLKEVMKESISAAASYVRSRSVDFGIEPPLFERRDIHVHVPEGATPKDGPSAGVAMATTIVSVLTGIPVRRDVAMTGEITLRGRVLPIGGLKEKLLAALRGGIKKVLIPEENAKDLADIPDNVKNALEIIPVSRMDEVLHHALLRHPEPISWTEQPVSGAVVPDEDAAGVVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYI7</accession>
    <name>A8HYI7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative acyl-CoA hydrolase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170148.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1620"/>
    <dbReference type="EnsemblBacteria" id="BAF87618">
        <property type="protein sequence ID" value="BAF87618"/>
        <property type="gene ID" value="AZC_1620"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1620"/>
    <dbReference type="eggNOG" id="COG1607">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050164_2_0_5"/>
    <dbReference type="OMA" id="MDEMAFL"/>
    <dbReference type="OrthoDB" id="1712258at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="128" mass="13680" checksum="2FAF3BB439110E08" modified="2007-12-04" version="1">MPDTAEPTGELTLRTLAMPADANPSGDIFGGWVMAQMDLAAGIRAAEVAAGRVVTAGVKEINFRLPVKVGDTMCIYTNLLKVGRTSMTLDVQAWARRQHSAVREKVTEAVFVMVALDAEGRPRPVSPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8HYP1</accession>
    <name>A8HYP1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3 7">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_4483</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15009"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3 7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173002.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4483"/>
    <dbReference type="EnsemblBacteria" id="BAF90481">
        <property type="protein sequence ID" value="BAF90481"/>
        <property type="gene ID" value="AZC_4483"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4483"/>
    <dbReference type="eggNOG" id="COG0262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043966_5_1_5"/>
    <dbReference type="OMA" id="RDNQLPW"/>
    <dbReference type="OrthoDB" id="1920912at2"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="F:NADP binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:one-carbon metabolic process"/>
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        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
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    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="9">
        <location>
            <begin position="3"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF90481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="169" mass="18687" checksum="9FF062998627DDD7" modified="2007-12-04" version="1">MRPLVQIVAMAENGVIGRDQKLPWHLPSDLKRFRALTTGKPILMGRHTYLSIGRPLPERISVVVSRDPGFAPPPQVRVATTLAAALRLADDAAGQMGAPEIAVIGGRQIFAETEPLSSLVHLTLVHAEPDGDVRLPPYDPARWRERERQGPLQGPQDEYAFSYVTLEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZ11</accession>
    <name>A8HZ11_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">FixO protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fixO</name>
        <name evidence="7" type="ordered locus">AZC_4524</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173043.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4524"/>
    <dbReference type="EnsemblBacteria" id="BAF90522">
        <property type="protein sequence ID" value="BAF90522"/>
        <property type="gene ID" value="AZC_4524"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4524"/>
    <dbReference type="eggNOG" id="COG2993">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_050647_1_0_5"/>
    <dbReference type="OMA" id="TDWHENH"/>
    <dbReference type="OrthoDB" id="1469969at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003468">
        <property type="entry name" value="Cyt_c_oxidase_monohaem-su/FixO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02433">
        <property type="entry name" value="FixO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00781">
        <property type="entry name" value="ccoO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="57"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="246" mass="27642" checksum="8EDA304684006C41" modified="2007-12-04" version="1">MSATSIWSKHAIFEKHSILLLLGVLIVISIGGLVEIVPLFYLKSTIEKVDGVRPYTPLELAGRNIYLREGCYLCHSQMIRPLRDEVERYGHYSLAAESMYDHPFQWGSKRTGPDLARVGGKYSDLWQLEHLNNPRAVVPASIMPAYPWLAKTPLQAKHIADDMKVLRAEGVPYTDEMIASAQDDLKLQATPEADADALQKRYPKAQARDFDGNPGELTEADALIAYLQQLGTQVDFKLYDNKANVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZB7</accession>
    <name>A8HZB7_AZOC5</name>
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        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">ftsZ</name>
        <name evidence="9" type="ordered locus">AZC_4564</name>
    </gene>
    <organism evidence="9 10">
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012173145.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4626"/>
    <dbReference type="CAZy" id="GT2">
        <property type="family name" value="Glycosyltransferase Family 2"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90624">
        <property type="protein sequence ID" value="BAF90624"/>
        <property type="gene ID" value="AZC_4626"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4626"/>
    <dbReference type="eggNOG" id="COG1215">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2148">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_447352_0_0_5"/>
    <dbReference type="OMA" id="PRISLIM"/>
    <dbReference type="OrthoDB" id="1759731at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0270">Exopolysaccharide synthesis</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="417"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="4">
        <location>
            <begin position="412"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF90624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="610" mass="66781" checksum="B7522F74C1A3A9F1" modified="2007-12-04" version="1">MIALELLFWLSLVLVAYHHAVFPALLRALARRRGPRPVPPPVPEADLPVITLVVPAYQEAAFIAAKLKDCAALDYPRDRLKVIVACDGCTDGTPEAARAALASEACAGLNAEVRDFPVNRGKVAVLNEVIAGLPPGLVALSDVSASLSPDALRRAAAHFADPRIGVVAGTYALRAAGSAGEAGYWRYQTAIKADEAALAAPIGCHGAFYMFRRELWAPLPPHTINDDVILPMRMVAAGAGAVYDRAIVATEEERTHRAQEFRRRVRIASGNVQQALWLWRLGDPRRPDLAFIFLSGKALRAFVPFLLVILFVSNLLLAFYPLTLYRLLLVGQVAFYGLALFAIAKSAAPLPRVLRFAGYFVEGHGAGLIGALRQLTGKDRGRWGRAAESKAGMSAAGEPELDYVHPVVRVGKRAFDIVVGAIAFLVLAAVFVPVALAIKLTSKGPIFYRQIRVGRSTETRTDLFYLFKFRTMYVDAEARTGPVWATANDPRITPIGRFMRKTRIDELPQAINVLKGDMSIVGPRPERPAFFLKLEKEIPFYVERTHGLRPGITGLAQVNQGYDGSIEDVRSKVGYDHAYAMRLLDPWDWIKTDLSIIFRTAAVMVLGKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="97" xmlns="http://uniprot.org/uniprot">
    <accession>A8I072</accession>
    <name>A8I072_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mfd</name>
        <name evidence="11" type="ordered locus">AZC_1221</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169752.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1221"/>
    <dbReference type="EnsemblBacteria" id="BAF87219">
        <property type="protein sequence ID" value="BAF87219"/>
        <property type="gene ID" value="AZC_1221"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1221"/>
    <dbReference type="eggNOG" id="COG1197">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005122_0_3_5"/>
    <dbReference type="OMA" id="WAPPCRE"/>
    <dbReference type="OrthoDB" id="234717at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="636"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="818"/>
            <end position="972"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1171" mass="128286" checksum="98FF7675DED94516" modified="2007-12-04" version="1">MKRPRSLAEDLKAGNPLTLSRVPEGMQGLVVADLARSVAAGKDAPWPSLTVVCRDGQRLAALERGLAFFAPEIEVLSFPSWDCLPYDRASPNAAITARRMATLARLARVKGGEVSVLLTTVNATVQRVPARDLLAAQSLSARPGNAIALEGIVEWAERNGYLRTPTVRDTGEYAVRGGLIDLYPPGLDAPIRLDFFGDTLESIRAFDPETQRSSGTLHALELVPMAEFQLTTDTMRRFRMAYLAEFGANTKGDTLYEAVSEGRRHAGMEHWLPLFHAGLDTLFDYLDRTPFVVEAQVEDAAAERITQIGDYYDARKEALASGAPGAVYKPLPPERLYLTQDEWRSRLHALPLTRLTPFATPDGGAGKVVDVGGVEGRSFAAERADPEANVFDAAVTHVRDLQGRGKKVILAGWSEGSRERLSTVMADHGLKDLAPISKFATIDAMPRNKATLAIYGLERGFETPDFAIIGEQDILGDRLVRPKRKARRPQDVISELTSLTAGDLVVHVDHGIGRFIGLKAIEAMGAPHDCLEIHYAGGDKLFLPVENLELLTRYGSEDTEAQLDKLGGGGWQARKARMKKRIREMAGELIKIAAARQLSEAPRLVPAAGLYDEFRARFPYEETDDQEAAISAVLDDLSSGHPMDRLVCGDVGFGKTEVALRAAFAVALSGKQVAVVVPTTLLARQHFRTFSERFKGLPVNVAQASRMVTGKDLTAVKKGLTDGTVDIVVGTHALLGKTIQFRDLGLVIVDEEQHFGVAHKERLKALRSEVHVLTLTATPIPRTLQLAMTGVRELSLIATPPVDRLAVRTFVTPFDPLIVREALLRERYRGGQSFYVVPRIDDLAEVREFLEKSVPEVKVAVAHGQMAAGTLEDIMTAFYDGQYDVLLSTTIVESGLDVPNANTLIVHRADMFGLAQLYQLRGRVGRAKARAYAIFSVPATKPITAQAERRLKVLQSLETLGAGFQLASHDLDIRGAGNLLGDEQSGHIKEVGYELYQEMLEEAIAHLKAGITDYVDDKWSPNITIGMPVLIPEEYVTDLHVRLALYRRLADITEDAELDAFGVELVDRFGPAPEEVTHLLRLSQIKTLARKANVEKVDAGPKGVVLAFRENQFADPAGLVQLINAEGPQAKVRPDFKVVFLRDWATAEARLKGTLQVLRKLAGLVEKRKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0C1</accession>
    <name>A8I0C1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alanine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1239</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169770.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1239"/>
    <dbReference type="EnsemblBacteria" id="BAF87237">
        <property type="protein sequence ID" value="BAF87237"/>
        <property type="gene ID" value="AZC_1239"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1239"/>
    <dbReference type="eggNOG" id="COG3616">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_031639_2_2_5"/>
    <dbReference type="OMA" id="WPRFYGW"/>
    <dbReference type="OrthoDB" id="1512472at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-ser_dehydrat" evidence="2">
        <location>
            <begin position="258"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="381" mass="39525" checksum="3D7EA1BC1623DBD0" modified="2007-12-04" version="1">MTVAAALADLPTPCLILDEARMLRNIARLKTHLDGLGVALRPHLKTLKSVEAARRVLKDGNGPATVSTLKEAEVFAAAGVRDIIYAVGIAPQKLPRVIALRGAGCDLAVVLDTRVQAAAVAAMSRAVGDAIPALIEIDCDGHRAGLKPDDPEIVAIGRILHEGGAQLRGVLCHSGGSYGQVGPEALADFAEQERAAIVAAAETLRAAGLPCPVVSVGSTPTAHFARDLTGVTEVRAGVYVSQDLVMAGIGVCTPDDIALSVLATVIGHQSERGWTLVDAGWMALSRDRGTASQAVDQGYGLVCDVEGQVIPDLIVVGANQEHGIIGLRAGSTATAPDLPVGAQVRILPNHACATATEFDDYAVLPADGSAHIARWSRFRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8I0E0</accession>
    <name>A8I0E0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_1246</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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        <property type="protein sequence ID" value="BAF87293.1"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1314"/>
    <dbReference type="eggNOG" id="COG2207">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_88_4_5"/>
    <dbReference type="OMA" id="HRWLLKM"/>
    <dbReference type="OrthoDB" id="1268974at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="200"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="317" mass="35082" checksum="8370F0E463539858" modified="2007-12-04" version="1">MELANYGKRLDDHWRGICSASQISAPGHSDVGLSVARITGGPNFGFVDPVPAQDGYALSLELIDYQRGDLWLDGRNTPQIDLKRNNSVLFDLRHKVEARLEDPFDTIHFHIPHRYFDALCVASGRPAISDLNFVSGHGFFDQTLMHLGMAMIPALERPAESSHLFLDQMMVALCTYLANTYGVALETRPGPQGLVPWRLKRAKDLIASRLSGNLTIAEIAADCGLTPSYFTRQFAASTGMTPHRWLLKMRVEAAKQLISEGRLSLVEVALSCGFADQSHLTRIFSREVGTPPRTWARNMLPRHLATPAGVRSGEGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1L4</accession>
    <name>A8I1L4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_1394</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169922.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1394"/>
    <dbReference type="EnsemblBacteria" id="BAF87392">
        <property type="protein sequence ID" value="BAF87392"/>
        <property type="gene ID" value="AZC_1394"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1394"/>
    <dbReference type="eggNOG" id="COG2080">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052511_3_0_5"/>
    <dbReference type="OMA" id="EHDVPQC"/>
    <dbReference type="OrthoDB" id="1819473at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="150" mass="15537" checksum="2D102776E15177D2" modified="2007-12-04" version="1">MSAISINGKTYQIASDPDTPLLWVLRDELGLTGTKFGCGVAQCGACTVHVDGVAVRSCQMPVGTVGTRAVTTIEAVGDTPAGAKIQKAWLDLEVVQCGYCQPGQIMSATALLAANPKPDDAAIDAAMAGNLCRCGTYVRIREGIKHAAQS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-05" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1W4</accession>
    <name>SECB_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein-export protein SecB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">secB</name>
        <name type="ordered locus">AZC_4672</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecB family.</text>
    </comment>
    <comment type="sequence caution" evidence="2">
        <conflict type="erroneous initiation">
            <sequence resource="EMBL-CDS" id="BAF90670" version="1"/>
        </conflict>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90670.1"/>
        <property type="status" value="ALT_INIT"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_043879833.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I1W4"/>
    <dbReference type="SMR" id="A8I1W4"/>
    <dbReference type="STRING" id="438753.AZC_4672"/>
    <dbReference type="EnsemblBacteria" id="BAF90670">
        <property type="protein sequence ID" value="BAF90670"/>
        <property type="gene ID" value="AZC_4672"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4672"/>
    <dbReference type="eggNOG" id="COG1952">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_111574_0_0_5"/>
    <dbReference type="OMA" id="CPNVLFP"/>
    <dbReference type="OrthoDB" id="1624074at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00821">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003708">
        <property type="entry name" value="SecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36918">
        <property type="entry name" value="PTHR36918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02556">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01594">
        <property type="entry name" value="SECBCHAPRONE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54611">
        <property type="entry name" value="SSF54611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00809">
        <property type="entry name" value="secB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0143">Chaperone</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0653">Protein transport</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
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    <keyword id="KW-0813">Transport</keyword>
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        <location>
            <begin position="1"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000305" key="2"/>
    <sequence length="160" mass="17272" checksum="3CB5D3602E00B039" modified="2008-02-05" version="2">MATQNGSPTDNTAPALNVLVQYIKDFSFENPNAPRSLGAPQGQPDVNIQINVNARPLAPGEFEVELKIEGGAAVQGNTLFAFDLTYGGIFRLMNVPEQSLQPVVLIECPRLLFPFARQIVADAVRGGGFPPLMIDPVDFAALYQQRMMAEAQNLQTAGQA</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF90698.1"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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        <location>
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            <end position="584"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <source>
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    </evidence>
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    </evidence>
    <sequence length="300" mass="32811" checksum="05DC58371AA713A3" modified="2007-12-04" version="1">MAPIVHAVGHLKILVSDPDAVIRDATEILGLHVTNRQEGQTWLSSNGRSAELVLLHAGENATHTIGLEALTVEAVRAAEARVAQLGCRIESSQPSLTCMAAGVTFTTPEGLRFEIHTPVKDTIYGRRQPSTGVGANRMDHINLITPDPAATRSQLEGIGGLMLSERLVDDSLSWMYGGNRQHHILGLVKGTVGLHHYSFEFLEFNQYLRLGDTLDRFGKQMLWGPGRHRPGDNTYAYYVEASGAMVECSGAMALVADDATFEPNVITNLQRPGNVRQMNVWGTPAPLEWRTHHFPFAAIG</sequence>
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                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <subcellularLocation>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="103"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="316" mass="33590" checksum="3B0CEA1D7B548BE3" modified="2007-12-04" version="1">MALTTASPERTPNWFARAWDSDIGHSFRTSPVTMLAAFVVLVIALAALFAPWIAPTDPFDPASLNLMDGKTPPLTPSAFTGNEFLLGTDDQGRDVFSAILYGARMSLLVGLASVAVSIGLGVGLGLLAGYRGGWLDSLIMRVADIQLTFPDILVAMLIFGVARGAVPVTAQESIAIPVLILSIGVSKWPQYARTVRGLTLVERGKDYVAAARVVGLPQATIMRRHILPNVIGPVLVIATLGLSLAIITEATLSFLGVGAPPTQPSLGTLIRIGQEYIASGEWWILFFPAVTLLAIALSVNLLGDWLRDALNPRLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3F7</accession>
    <name>A8I3F7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-threonine aldolase</fullName>
            <ecNumber evidence="3">4.1.2.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2018</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-allo-threonine = acetaldehyde + glycine</text>
            <dbReference type="Rhea" id="RHEA:26209"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58585"/>
            <dbReference type="EC" id="4.1.2.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-threonine = acetaldehyde + glycine</text>
            <dbReference type="Rhea" id="RHEA:19625"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.1.2.48"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the threonine aldolase family.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.48" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2018"/>
    <dbReference type="EnsemblBacteria" id="BAF88016">
        <property type="protein sequence ID" value="BAF88016"/>
        <property type="gene ID" value="AZC_2018"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2018"/>
    <dbReference type="eggNOG" id="COG2008">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_049619_0_0_5"/>
    <dbReference type="OMA" id="ETDCEVF"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008732">
        <property type="term" value="F:L-allo-threonine aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006567">
        <property type="term" value="P:threonine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026273">
        <property type="entry name" value="Low_specificity_L-TA_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038940">
        <property type="entry name" value="Low_specificity_LTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="29"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="366" mass="39142" checksum="538EAA708BDA2467" modified="2007-12-04" version="1">MVTGQDQRGRPAVSQDRQSLEQQQSQPQQFASDNYAGICPEAWAAMAEANEGSAVAYGDDDWTHRASDAFRALFQTNCEVFFAFNGTAANSLALASLCQSYHSVICAASAHVETDECGAPEFFSNGSKLLVATTDGGKLTPDAVLALATGRSDIHYPKPRAVTITQPTETGQVYTLDEIAALSATCRDLGLRLHMDGARFANACAALGCSPAEMTWKVGVDVLCFGGTKNGMAVGEAILFFDRALALDFDYRCKQAGQLASKMRFLSAPWVGVLESGAWLRNAAHGNACARRLAAAIADVSGIEPMFPVEANAVFLRAPEAVLQGLRENGWRFYTFIGGGARFMFAWDADLARVDQLAADIRAIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I441</accession>
    <name>A8I441_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Lipoprotein releasing system transmembrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lolC</name>
        <name evidence="12" type="ordered locus">AZC_1687</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Liu C.T."/>
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                <person name="Wiley G.B."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="570" mass="61451" checksum="ACAA2B99A2B83E28" modified="2007-12-04" version="1">MRKPQNLVYGVDDLPPARVGLLSALQQVAFLSALLSVPSIALANLGLDDDQFLRLAAATLFCSGFVLVLQGFGIGGVGARLFYPLQCTTAAIPALVYASSAGLSLAENFTMVGMVGVSQVLFSFVIFRLRAIFTVEVAGLAVFLIGVGLGQQGLFLVLDLPPDRPDAIAHLTIVGVTLATLVILHVYVQSRLRLFTNLIGLCVGMVLSVALGQLDPHDLRLFADARVVDFPRPPLFGWAFNLGAVIPFMVTGFVFALTSMGVQTIAQRNNDRDWKSPDLVSIGRGIRAEGVMHMMAGFLNAMPMVASGGAVALAAASGCTARALAFWTGGLLMTFSLLPKVIGFWLLMPVSVTGALFIFLSTFTTVNGIQLVASRVLDARKVLAIGMGFVAAIAYEPLHRLLDGQVPGLRLFTFSAFAVSILVTVVLLAIFRIGVTRKVVRRFPASGARHDDVANFIEAEGARWSARVDVVQRAAQVTWHALELIGRDYVDPERPVIEVTTRYNDILFDIVLRYEGTAPALASRPPTAEELLENPALAEQLTGFLITRLAPDLKIQRIGSSWELHFRLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I538</accession>
    <name>A8I538_AZOC5</name>
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        <submittedName>
            <fullName evidence="4">Acetyl-coenzyme A synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_1809</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170337.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1809"/>
    <dbReference type="EnsemblBacteria" id="BAF87807">
        <property type="protein sequence ID" value="BAF87807"/>
        <property type="gene ID" value="AZC_1809"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1809"/>
    <dbReference type="eggNOG" id="COG0365">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_59_10_5"/>
    <dbReference type="OMA" id="IACIRAG"/>
    <dbReference type="OrthoDB" id="326708at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0007">Acetylation</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="37"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="449"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF87807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="537" mass="58224" checksum="A975D886A709133D" modified="2007-12-04" version="1">MLPEAARYDDLVRAFRWRIPERFNIGTACVDAHADGSGKPALLFVEESGALVTYTFDELKRLTNRFANVLAACGLERGDRLAVFLPQAPETAIAHLAAFKAGLVSVPLFTLFGDEALSFRLANSGAKALVTDLAGLAKLDRIRHEVPDLTHVFVTGPDQGDGRAISFDAAMARASDAFTPSDTGPDDPAIIIFTSGTTGNPKGALHGHRILLGHLPCIEFIHQGMPQPGDLHWTPADWAWIGGLFDVLFPTLYLGVPVLAHRAKKFDPDAAMALMATHKVRNVFLPPTALKLLRQADVRHPGLVLRSLLTGGETLGAELGAFVQERLGVEAREIYGQTECNLVVGSNSNFFAIRPGAMGKPIPGHDVRIVDEDGVEVPTGEQGHIGVRRGDPVMMLEYWNNPAATADKYAGDFLLTGDLGRQDEEGYLWYMSRSDDVITSAGYRIGPGEIEDCILRHPAVAMVGVVGVPDPVRTEAIKAWVVLKPGQLGSDALAAEIQDHVRTRLSGHEYPRYVSFTDALPMTATGKILRRELRRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="56" xmlns="http://uniprot.org/uniprot">
    <accession>A8I553</accession>
    <name>A8I553_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ordered locus">AZC_1818</name>
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    <organism evidence="1 2">
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170346.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1818"/>
    <dbReference type="EnsemblBacteria" id="BAF87816">
        <property type="protein sequence ID" value="BAF87816"/>
        <property type="gene ID" value="AZC_1818"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1818"/>
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    <dbReference type="OMA" id="VLTPGMY"/>
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        <property type="component" value="Chromosome"/>
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    <dbReference type="InterPro" id="IPR025841">
        <property type="entry name" value="CP_ATPgrasp_2"/>
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    <dbReference type="InterPro" id="IPR016450">
        <property type="entry name" value="UCP005522"/>
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    <dbReference type="Pfam" id="PF14403">
        <property type="entry name" value="CP_ATPgrasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005522">
        <property type="entry name" value="UCP005522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="471" mass="52834" checksum="4968A23CA2D0C142" modified="2007-12-04" version="1">MARAFDEMSSDDGSVRKAYETLNRWLSNVPHDVLDHRRKEAEFIFRRIGITFAVYGEQNAQERLIPFDIVPRIITNDEWTRLARGLEQRVKALNLYIKDVYSKREVLRAGIVPEDLVYQNPAFRPEMNGQPVPHDLYVHIAGIDIVRTDPDTFYVLEDNARTPSGVSYMLENREIMLRLFPELFSLHRVAPVENYADDLLATLRSLSPNGAHEPNVVILTPGIYNSAYYEHSFLADKLGVDLVEGRDLFVKDSIVYMRTTEGPKRVDVIYRRLDDDFLDPLAFRPDSVLGVPGLMSAYKAGNVTLTNAVGTGVADDKAVYSYMPEIIKFYLGEEPLLANVPTWRCREADHLKYVLEHLEELVVKEVHGSGGYGMLVGPKSDKAQIEAFRAKLKADPSNFIAQPTLALSTCPTLVDQGIAPRHVDLRPFILSGSDKVRIVPGGLTRVAMKEGSLVVNSSQGGGTKDTWVLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5E4</accession>
    <name>A8I5E4_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Putative MFS permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2268</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2268"/>
    <dbReference type="EnsemblBacteria" id="BAF88266">
        <property type="protein sequence ID" value="BAF88266"/>
        <property type="gene ID" value="AZC_2268"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2268"/>
    <dbReference type="eggNOG" id="COG2271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_001265_0_0_5"/>
    <dbReference type="OMA" id="FTAYMSD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="34"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="446" mass="48319" checksum="296AD2D2BDDA9A34" modified="2007-12-04" version="1">MLGETAMSSIAMDASAADGEAMRKRIASKLRWRIVFYCFVLFIVNYLDRVNVGFAATHMNKDLGLSATAYGFGAGVFFLGYIAFEIPSNMMMHKVGARIWIARIMVTWGLISCAMAFIQGETSFYILRFLLGAAEAGFVPGILLYLTYWFPARDRAKATAGFMTATVLSTVIGAPISGWILATVPNWHGLANWQWLFILEGLPAVILGVFTFFYLVDRPQDGRWLDEAEREWLIAELERENREVANTGAHEYGAIFRDPRVWLLTLIYMFNAMAVYGVVLWLPQIVRSIGGLSDIQTGFVTAVPFVFAAIGLVLVARSSDRTGERKWHTALAALFGGLFLAASAVAPTPLVGLMLISAAAFGVWAVLGVFWSLPTQFLTGAAAAAGLAAINGFAQIGGFAGPYLVGWIKDTTQSFTPALLTLAAGPVIAAILCLAIKVKAPAGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5F9</accession>
    <name>A8I5F9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized conserved protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2274</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </evidence>
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        <source>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF88347.1"/>
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    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_2349"/>
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    <dbReference type="EnsemblBacteria" id="BAF88347">
        <property type="protein sequence ID" value="BAF88347"/>
        <property type="gene ID" value="AZC_2349"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2349"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
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        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="463" mass="49331" checksum="71DA1D3B4ED905B4" modified="2007-12-04" version="1">MTAPRLRILSVEVRERMMPFVRPFRFGPSVVEAAPQAFVRIELEVEGAGRAVGQAAEMMMPRWFDKAPHKSPEQTVDDLRRVLLHAAALYADAPWSTAYGLSADAAAMQLGWAEGRGIPALAAHFGPALLDKAVVDALLRALSLTFPEGLSRNVMGLDARNARDLSPEQIPALLASLTPVPAVAVRHTIGLLDPLEGPHGLSAEIAAARLRFFKIKIGGDLAADLDRLAAITALLTHLAPDFRATLDANEQYDPERLCQLAAGLDTPALRPLKARLLYIEQPFDRTETFTRPLPPALDGIPVIIDEADGGLDAFPRAIALGYRGVSSKACKGLYKSILNAVRVQAGEGTFLTAEDLTCQPGLGLQQDLALVATLGLTHGERNGHHYVAGFGPAPEEEAGAFAAAHPDLYRLTDAGAALDVSRGVLATASLLSAPGFAGRAEPDWASLAPVTLPETRLHQEIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8I636</accession>
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        <name evidence="2" type="primary">rpiA</name>
        <name evidence="3" type="ordered locus">AZC_2358</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88356.1"/>
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    <dbReference type="STRING" id="438753.AZC_2358"/>
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        <property type="gene ID" value="AZC_2358"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
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    <feature type="region of interest" description="Substrate binding" evidence="2">
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    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="157"/>
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        </location>
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    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="184"/>
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        <ligand>
            <name>substrate</name>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
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    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF88356.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="292" mass="30513" checksum="61CF71AB4E2EB07C" modified="2007-12-04" version="1">MPPCRRFGRTFKGGVCGTARVAGAPLCLFKPGGRGTRRCASRLRFAPFAARQPANRWSTDMADAEELKRAAAAKALEYVTDGMRLGLGTGSTAKHFVALLAERVAAGLKVTGVPTSEQTKAQALSLGVPLATLDELPELDLCIDGADEIGPELALIKGGGGALLREKIVASAAREMIVIADETKTVATLGRFPLPIEVVTFGVEAIKLRLKGAIATAGCDGELKLRHKADGKPFITDQGNVIVDAHLGRIPDPRALARALEEVAGVVEHGLFLGLARRAVLAGANGISVITP</sequence>
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            <fullName evidence="2">Putative myo-inositol monophosphatase 2 family protein</fullName>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF88377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF88377">
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        <property type="gene ID" value="AZC_2379"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2379"/>
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    </dbReference>
    <dbReference type="HOGENOM" id="CLU_044118_3_1_5"/>
    <dbReference type="OMA" id="NYGWISE"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Inositol_monophosphatase_CS"/>
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        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="291" mass="29997" checksum="ABCEAD3159BAA467" modified="2007-12-04" version="1">MPRTCEALKGSPMKSQDQTPPRSGAPAPDAPDAIARLMADAVTAAGAIALDMFRAGRLESWSKANDSPVTAADIAVDRFLKDRFTALAPDYGWLSEESVDSPDRLARSRVWVVDPIDGTRGFMAGGVDWAVSAALVENGRPVAAALFAPASEELFVASVGAGATRNGVPLAVSDLTALAGARISGPVASLDRLAQHAPIERRPRVRSLALRITRVATAELDVALAAPNAHDWDIAAADLLVQEAGGLLSGLDGRPLTYNATVPRHGALVCAGTALHPHILAAARAGAGGAS</sequence>
</entry>
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        <alternativeName>
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    <reference evidence="12 13" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="13" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="12 13" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="function">
        <text evidence="2 10">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="4 10"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170908.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2382"/>
    <dbReference type="CAZy" id="GT30">
        <property type="family name" value="Glycosyltransferase Family 30"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF88380">
        <property type="protein sequence ID" value="BAF88380"/>
        <property type="gene ID" value="AZC_2382"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2382"/>
    <dbReference type="eggNOG" id="COG1519">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036146_1_1_5"/>
    <dbReference type="OMA" id="FIKYEFW"/>
    <dbReference type="OrthoDB" id="1163086at2"/>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_N" evidence="11">
        <location>
            <begin position="41"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="9">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF88380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="431" mass="46983" checksum="9BE4E17E772A1348" modified="2007-12-04" version="1">MTRRPLPVPLRLYRGAASFATVLAPAWLKYRVRKGKEDPARIAERRGITRVERPQGPLIWVHGASVGEIVSILPLVERLQDRGFAILLTSGTLTSSRVAARRAPASVIHQFVPLDAPAFVRRFLDHWKPDLALLAESELWPNLMTELDKRGTAVVLVNGRLSARSAQRWARLPRSARALLSRVDLCLAQTPEDAARFRGLGAPRVQVAGNLKFDVPAPPADPSMLARLQAAIGERPVLLAASTHPGEDEYVLEAHGRLRQDLPGLLTIIAPRHPERGGAIRQLAHDAGFAATQRSQAPLPLPEAEVYVADTIGEMGLFYRVAPVAFLGGSLIEHGGQNPIEPAKIGTVVLHGPHVWNFAAVYGRLDEAAGSVPVMDAEDIVRATLDIFFTPGCHERISHAAWQTVENLSGALPRTLAAIEPYLLQIRLEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8I746</accession>
    <name>A8I746_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_2078</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170605.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2078"/>
    <dbReference type="EnsemblBacteria" id="BAF88076">
        <property type="protein sequence ID" value="BAF88076"/>
        <property type="gene ID" value="AZC_2078"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2078"/>
    <dbReference type="eggNOG" id="COG1173">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028518_1_1_5"/>
    <dbReference type="OMA" id="QRWRLTV"/>
    <dbReference type="OrthoDB" id="1734230at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="214"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="90"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF88076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="295" mass="31535" checksum="E262B2C25C280590" modified="2007-12-04" version="1">MAASSPSDAGALPVSRPRYLPNLSRLRFAPTVAAVCLVLIAAMALLAPLLAPHDPITMLPTQRLKPPSPMYLLGTDSYGRDLLSRLIYGARVSLIVGLGVMVISIAIGLPLGLLSGYFRTLDAILMRVMDGLMAIPSVLLAIAVVSLSGSSLTTVMIAITIPEVPRVVRLVRSVVLSARNEPYVEAAIAMGTRLPALLYRHLMPNTYAPLIVQGTYICASAIVTEAILSFLGAGIGTETPSWGNMISEGRMYFQLKPMLIFWPGLLLSMCILSVNLIGDAARDVLDPRLKKRTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="73" xmlns="http://uniprot.org/uniprot">
    <accession>A8I842</accession>
    <name>A8I842_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamine amidotransferase of anthranilate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2207</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
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    <feature type="domain" description="GATase" evidence="1">
        <location>
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            <end position="187"/>
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    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88205.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="200" mass="21619" checksum="0B47C3570F786D02" modified="2007-12-04" version="1">MTAVTLIDNYDSFTYNLWHYLGELGATVTVRRNDAMDVEGILGEKPDAIVLSPGPCTPNEAGICCDLIAKASDTVPMFGVCLGHQAIGQVFGGDVVRAPTPMHGKMSEILHEGRSVFRGLNHSFQATRYHSLIVARETLPADLEVTAHTADGLIMGLAHRTRPVHGVQFHPESIASENGHALMRNFLDIATAFNAARAKD</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
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        <property type="protein sequence ID" value="BAF88666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="protein sequence ID" value="BAF88666"/>
        <property type="gene ID" value="AZC_2668"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="RND_pump_MFP"/>
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    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="99"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="138"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    <evidence type="ECO:0000256" key="3">
        <source>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF16576"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88666.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="425" mass="44477" checksum="12C52F4BCD8D4BD4" modified="2007-12-04" version="1">MTASVSPSEPAVTGVSDPSPSTRSSSPWRRRLLLGAVVLVAIGAGIYVVPSALKPAGGAASAAAPGSPPPVPVAVATVEARDTRLYESFSGRLEAVERVEVRSRVAGAIKAVHFREGALVKAGDLLVTIDPEPYQAALDEADAQVASAEAQLELARNELERGERLFTSRTLSQRDLDERLNTQRAAQAALRAAEARRTVARLNLSYTQVRAPVAGRVGKSEITVGNLIAAGPGAQLLTSLVSVDPIYASFNADEATVAQALAALGTGADVTERLDRIPVRMTAGGNPPVTGVMQLVDNQVDPRTGTVRVRARFANPDGHLLPGQFARLEMGQPQSAPAVLVSERAVGTDQDKKFVFVVDADNKAVWREVTLGAPVDGLRVVTRGLSAGERVVVNGLHRVRPGAAVTPETAPMQVTEATSRSAAAN</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="45" xmlns="http://uniprot.org/uniprot">
    <accession>A8I984</accession>
    <name>A8I984_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2756</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2756"/>
    <dbReference type="EnsemblBacteria" id="BAF88754">
        <property type="protein sequence ID" value="BAF88754"/>
        <property type="gene ID" value="AZC_2756"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2756"/>
    <dbReference type="eggNOG" id="ENOG5030AF6">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_080348_0_0_5"/>
    <dbReference type="OrthoDB" id="2124401at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721543" evidence="1">
        <location>
            <begin position="36"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="315" mass="33131" checksum="B42BDEE8342A4027" modified="2007-12-04" version="1">MRADTRTYALRWRVMRRRLFAAGLLAVLLPLPVQADPIDAYVAARDQAIAASLAAAKAGKADDPAVQKQEEASAAELARLLSVALGPLAFEGMGPPRYSLGTFAEDAATPTRRLDGLAFANADYSTRLVVTPEAVFTAWLAARAKDDGAPRALRSGLPTAVGTAEFFQNAIAGDGGYFQPYVALPVAASPGETALAVLGLQVDEPAGTTAPNEISILRIGNGRAVVGMTMAKLTIGPIPACEAVWTPYKVKADALARMLAKEKKPSANRQDEITRLASDGTDAYRACFAREAPKQAFFTAAVKAAEAFLALARGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9S1</accession>
    <name>A8I9S1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Putative cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_2825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171349.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2825"/>
    <dbReference type="EnsemblBacteria" id="BAF88823">
        <property type="protein sequence ID" value="BAF88823"/>
        <property type="gene ID" value="AZC_2825"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2825"/>
    <dbReference type="eggNOG" id="COG0031">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_021018_1_0_5"/>
    <dbReference type="OMA" id="WMADYGF"/>
    <dbReference type="OrthoDB" id="1677960at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="10"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="343" mass="36188" checksum="B5136606CB2E5B26" modified="2007-12-04" version="1">MNFRDGLVESIGNTPLIKLKKASELTGCTILGKAEFMNPGQSVKDRAALGIIRDAIAKKQIEPGGVIVEGTAGNTGIGLALVAAPFGFKTVIVIPETQSQEKKDMLRLAGATLVEVPAVAYANPNNYVKVSGRLAQEIAKTAPHGAIWANQFDNVANRQAHIDTTGPEIWDQTDGKVDGFVSAVGTGGTFAGVGMALKARNKDVKIALADPLGAALYSYYTTGELKAEGSSITEGIGQGRITANLEDAPVDHAFQITDEEAVPIVFDLLEHEGLCLGGSSGINIAGAIRLAKELGPGHTIVTILCDYGTRYQSKLFNPDFLRSKNLPVPAWLEARADVPNVLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="69" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA30</accession>
    <name>A8IA30_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Twin-arginine translocation pathway signal</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_2457</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
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    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
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    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily.</text>
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        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF88458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="351" mass="37611" checksum="0C4AF7FC57741475" modified="2007-12-04" version="1">MSEVVLQSIVKRYEHMVAVDHVSLSIGQGELVALLGPSGCGKTTTLRMVGGFVPVTEGRIMVGGRDVTHLPPHKRNMGFGFQNYALFPHMSVAQNVAFGLEMRKVSKADIAARVKTALDKVRLGHLSERLPKQLSGGQQQRVALARALVIEPDVLLLDEPLSNLDAQLRQEMKLEIRQIQRSLGITTIFVTHDQDEALSVSDRVVVMRAGRIEQEGSPDEVFATPKSHFVAEFMGVTNLLPGRPDTGGFRLATGEVVPVAGPPPGKEDVALGVRPERIVIAVGEGGQGHLPGRVELATYRGLVIDYQVRAASGLTLTARCPSPAAGGPSPLNAGQPVHVSWQPEAAVLVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A8IA81</accession>
    <name>A8IA81_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="9">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">potA</name>
        <name evidence="11" type="ordered locus">AZC_2476</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2476"/>
    <dbReference type="EnsemblBacteria" id="BAF88474">
        <property type="protein sequence ID" value="BAF88474"/>
        <property type="gene ID" value="AZC_2476"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2476"/>
    <dbReference type="eggNOG" id="COG3842">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_1_5"/>
    <dbReference type="OMA" id="LPQQDEC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015417">
        <property type="term" value="F:ABC-type polyamine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="12"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="370" mass="39795" checksum="EE3B165A28031BF6" modified="2007-12-04" version="1">MSRSRLMSSSSLSVHGLGKRYGEFVALAPTDLEVAAGEFLTLLGPSGSGKTTLLSLIAGLAAPDDGAIRIGGADVTYRPPYERDLGMVFQNYALFPHMTIEDNIAFPLKMRKVKGADAKKRAAEALELVRLPHVAKRFPRELSGGQQQRIALARCLVYRPSIILMDEPLGALDKKLREHMQLEIKRIHRELGTTIVYVTHDQEEAMTMSDRICLMNSGKIEQLGAPGDLYFRPRTVFVADFLGESNLLPAQVDRNEAGTLAVTLDGGAGSGQAIGNGADLAAGAKVTVMVRPQNITVRPAGEGSGRLKGRLTDIMVTGSLTKLYLEALAPGLPQLVAAYPTRTLSDDHSIGDVLELDWQAQDAVAIPAGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAA1</accession>
    <name>A8IAA1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gntR</name>
        <name evidence="5" type="ordered locus">AZC_2483</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
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        <property type="entry name" value="TF_FadR/GntR_C"/>
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    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="31"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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    </evidence>
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        <source>
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    </evidence>
    <sequence length="244" mass="27064" checksum="C637A67A1C9E7339" modified="2007-12-04" version="1">MHAHFLCGPCPENSRSTLRMVTETDAGTAAPRLTEVAYRQLLDMILSGALEAGSLVQERKLAKQLDVSRTPLRDALFRLEGEGLLIRRGEGALQVKTVTLEDYSHALRVRLVLEREAARLAAGHVPPVTLAALRARIEAVTQHEEGDDPHPSRTDLDGTDDDLHDVVANASGNPLLAELIRQVRQRSRLFGLERRPRRIGEIAREHLAILDAVASGDADAAEQAMARHIGNVMEDLRQRFFDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAM2</accession>
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    <gene>
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        <name evidence="11" type="ordered locus">AZC_2525</name>
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    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell inner membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2525"/>
    <dbReference type="EnsemblBacteria" id="BAF88523">
        <property type="protein sequence ID" value="BAF88523"/>
        <property type="gene ID" value="AZC_2525"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2525"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
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    <dbReference type="OMA" id="WAILLIN"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="156" mass="16476" checksum="3D4B015CC638A5B0" modified="2007-12-04" version="1">MRSRSVILPGGAALCSNLLQRSMRANMIPAVLVFLGAGFGGLMRHIVNITTVRLFGTLSFPFATMFINVLGCFIMGALTAAFAMRAGQGSFWTQHVRLLLTTGMLGGFTTFSTFSLEFAVLVERGEMGPAAAYAVGSLVLCLVGVFAGLSLIRAMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="59" xmlns="http://uniprot.org/uniprot">
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    </protein>
    <gene>
        <name evidence="2" type="primary">parA</name>
        <name evidence="2" type="ordered locus">AZC_2585</name>
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171109.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2585"/>
    <dbReference type="EnsemblBacteria" id="BAF88583">
        <property type="protein sequence ID" value="BAF88583"/>
        <property type="gene ID" value="AZC_2585"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2585"/>
    <dbReference type="eggNOG" id="COG0455">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_096711_0_0_5"/>
    <dbReference type="OMA" id="NDYLWHE"/>
    <dbReference type="OrthoDB" id="1370117at2"/>
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        <property type="component" value="Chromosome"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
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    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88583.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="260" mass="27957" checksum="56EFEDDE0BED0F10" modified="2007-12-04" version="1">MTTIISVHSYRGGTGKSNISANVAALLAQSGHRVGVMDVDIRSPGIHVLFGLEPQNIDHTLNDFLWGRCSVDAAIVDVTRAAVPGTPRGRGQVLLVPSSMRTGEIARILKEGYAVEVLNEGIHELCRRLDLDYLIIDTHPGVNEETLLSVAISDTLLMVLRPDQQDYQGTAVTLELAMRLEVPQMLLVVNKVHSSIDAVELKGEIEAAYRSPVACVLPLSDDLVRLGSAAVLAAVTPNAPYVTALRDVLAYLEPRHASAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="72" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICH1</accession>
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        <submittedName>
            <fullName evidence="3">Putative lantibiotic modifying enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3208</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3208"/>
    <dbReference type="EnsemblBacteria" id="BAF89206">
        <property type="protein sequence ID" value="BAF89206"/>
        <property type="gene ID" value="AZC_3208"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3208"/>
    <dbReference type="eggNOG" id="COG4403">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009398_0_0_5"/>
    <dbReference type="OMA" id="HENLIAC"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04792">
        <property type="entry name" value="LanM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
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    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007822">
        <property type="entry name" value="LANC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025410">
        <property type="entry name" value="Lant_dehyd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017146">
        <property type="entry name" value="Lanti_2_LanM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13575">
        <property type="entry name" value="DUF4135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05147">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01950">
        <property type="entry name" value="LANCSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM01260">
        <property type="entry name" value="LANC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03897">
        <property type="entry name" value="lanti_2_LanM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4135" evidence="2">
        <location>
            <begin position="139"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="971" mass="101879" checksum="033737EA575FB497" modified="2007-12-04" version="1">MTPPLALTSGGSHRSGRQNGHRSVSGSRHAEPTRTVLPMPFSDILAPLAVARATRLEAALSAAGAPLSAGARRGAIEALLERLNAVAMPVLAEAFTGDTPPPAVARLFDDPPDFVPRERYAAFRAELMGADGLPCLDRWPVLRDRLTKICADWEYNIAAFAAHLAQDADALRWLVPAWRERIPDIADLKGGLSDPHAGGRSVWRVDFADGTRLAYKPRSLAAECAFSRLLAELAGDETVPAQRIPRVLDAGDHGWMEWIEQAPLADADDARSYMERCGGLLALVDLLRGGDIHPDNLVPAGAFPVIVDLECLFQPAPADLGQPDPLEDPHLFSNGILPVFTSFDGGARMVAIAAAGAGPVPLRPETVVRHPGTDWLFLGNRQVPSFADGPTLEGRALDIRDHAADLARGYAATLRGLIRRREALLAPGGALDAFRKVPCRLLCAATNIYALVLAPALLGEGATSEAVFTAHLARAAGREPLMADASHWGHVLEAEAAALSRLDIPAFLFRPDGREAWSVEGRPLGPVFAAPMFARVEARLWALDEAAVADRARLIAAAVTPAPSARVVTGPADVAALLRHCADQVAALAVPQETDAVVWARLWEQIPALIAPAGPGLYYGSSGIAVFLAEAGRVLDDPRLLDLARRALRPTSARVRAGAAGAIATGCGAGYAQGLGGLIAALCWCADLLDDPGLMDDAVALARETPQALAASTGVPDLMQGAAGLALGLGLLHQSAGDLSPFLTACGHAILEGSGLEANGTRHWPDGPQPGLPGLSHGTAGMAAALAHIHRVTGDAAYRDAALEALAYEDTMFNAEAGTWTGEGRASRLHHRMSSWCHGAPGIALARAMVMATLGPAAAPLAPTLETALELTRATPVPAADDLCCGEAGRLEILSVLSARLGRSDLMADVDQALAQRLPDWARGEARLLAAAAPRAPGDAALFRGWAGVGHLMVRRLAPHIARDVLLPWAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICS3</accession>
    <name>A8ICS3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Vicibactin biosynthesis non-ribosomal peptide synthase protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_3246</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pantetheine 4'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:47942"/>
        </cofactor>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3246"/>
    <dbReference type="EnsemblBacteria" id="BAF89244">
        <property type="protein sequence ID" value="BAF89244"/>
        <property type="gene ID" value="AZC_3246"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3246"/>
    <dbReference type="eggNOG" id="COG1020">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3319">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000022_2_13_5"/>
    <dbReference type="OMA" id="WELTYGE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031177">
        <property type="term" value="F:phosphopantetheine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043604">
        <property type="term" value="P:amide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010071">
        <property type="entry name" value="AA_adenyl_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001242">
        <property type="entry name" value="Condensatn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020806">
        <property type="entry name" value="PKS_PP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001031">
        <property type="entry name" value="Thioesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00668">
        <property type="entry name" value="Condensation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00975">
        <property type="entry name" value="Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00823">
        <property type="entry name" value="PKS_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01733">
        <property type="entry name" value="AA-adenyl-dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="5">
        <location>
            <begin position="985"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="4">
        <location>
            <position position="1020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1344" mass="144934" checksum="2A50046B58C3BD5D" modified="2007-12-04" version="1">MGGSAPQLQPGGRAMTHADAAVETKDHELKGYDLTPSQRRVWSLEQIGNSAVAGRPLLELGLSGPLDVTTLRTALDRLALRHPALRLRFRVHPGGRVLQLPDDAAALPLSVCDLSAQTSGDAAHAYQRIRNELAVPDIETGVPAQAVLVRLSAHEARLLIVLHPIICDTVSLDILADSFALLYADAEAGSAGLSLAGAPLAWLERPEASPETLSQWETRLADDHADATLPLAGRRETRVDGARSAQLQTLGTAEAEAARAAATACGTSLALFLSAAFGVLLTRYSGQTRLKYGVALDAPLGGERREIGRVADVLPLLLDLSSGLSFKDALGRVAEALDAARSHYVPFETLAQTFWVNNEDNGRGFLPSVHMHRPLPPAVVITPGGLRITAIAQPPLPLDADFLFISRDLPDGSIELVLDHPAGLFDPRLVDRALTHLARIIGAASAGPEKSLRDIQLVSPAELEALSRPYPDGARDDPRPVHALIAGHVPRAPETPAIFFGDTVWTRAALDRYANRIANMLLAAGARRESCVAVALRRSPEAIGAILGVLKAGAAFIPVEPDHPAQRNDHILADAGVAVILTTRALRAKLRPAQGTTVIELDAVNLAEVPDSDPLVTITDRQLAYVIYTSGSTGKPKGVAVEHGPLTRHLQATARVYEMDETSRELPFLPFSSDGGHERWMVPLMLGGSIVLPDKPLWTPEETFAAMRRHGVNNASFPTTYVQQLAEWAEATGEAPPVRLYSFGGEGMAQATFDLFSRALKAQTLINGYGPTETIMTPMVWKVRSGTSFEGTYAPIGRAVGLRRIYVLDPDLNPVPIGVTGELYIGGDGVARGYVNRPGATAERFIPDPFGGDGGRLYASGDLARWREDGTVEFVGRVDHQVKLRGYRIEPGEIEAALRTLPGVSECAVVLRHDAGQPALVAYAVPARGARLDGAEVRRALAGLLPEHMVPSAVVVLEKMPLNANSKLDRAALPAPGFALLEVVPPSTPLEADICAMWRDTLGLPEVGVTQNFFEMGGNSMAALRILGRIRKLKPEADVAIADLFNHQTIRDLATAIERGPRPGGGQLIHLRSTGRRPILYCFPGLLVSTREYVKLVDHLGPDQPATGFICYSLAEDKGREASVTEITARYAELVRAHSKGEPCFFLGWSWGGLLAYEAARMLGSDIDLKLIGMIDVCDMDTEFAIGAIPRFAPGEREALAARVEAWLARTPMAARWHDLIGAMDALAYDQFLRFVGNSPEGLPEDGPDIGSREHTFWVLIDNALIFRRHKMLPHDCPIQPWAAADSLNRGLNLIDWRQLSRRAAPAEIIEGTTHLHIIGAPAFHARFARKLDEAMTGFEQAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICS8</accession>
    <name>A8ICS8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferrichrome-binding periplasmic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3248</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3248"/>
    <dbReference type="EnsemblBacteria" id="BAF89246">
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        <property type="gene ID" value="AZC_3248"/>
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    <dbReference type="KEGG" id="azc:AZC_3248"/>
    <dbReference type="eggNOG" id="COG0614">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_038034_10_0_5"/>
    <dbReference type="OMA" id="GIWMFGG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="75"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="338" mass="36091" checksum="EAC3721E0ADE25AE" modified="2007-12-04" version="1">MTCRNRWFRGPAPARRGSGHRVFRAQPMPEQPSAGTRRNIGRRTILTLMRGGLLAAPFGVSAGPAPADATPPLRRLVALDYGLAETLLLLGLPPVGLVGAQDWNRWVGEPALPAGVVNLGSSREPNLELLQQLAPDAILSTPYLAGISHRLERIAPVLSFPMYVPDGQPLALATEALSRLAALTGRVSQGMAALAAVEQDFASARSRLSGTDRRPLLMVSLMDSRHVRIYGANSLFGAVLTRLDVANAYAGQTNFWGFTTLGIESLPPLADARLVFFDPVPPGTLAALAANPLWTRLPYVQAGRVSRLPPVLMFGALPSATRFARLLADALTGEHSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="102" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICX1</accession>
    <name>A8ICX1_AZOC5</name>
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        <recommendedName>
            <fullName evidence="2 7 8">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 13" type="primary">recA</name>
        <name evidence="13" type="ordered locus">AZC_2855</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the RecA family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171379.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2855"/>
    <dbReference type="EnsemblBacteria" id="BAF88853">
        <property type="protein sequence ID" value="BAF88853"/>
        <property type="gene ID" value="AZC_2855"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2855"/>
    <dbReference type="eggNOG" id="COG0468">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_040469_1_2_5"/>
    <dbReference type="OMA" id="DYGEQAL"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="11">
        <location>
            <begin position="47"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="12">
        <location>
            <begin position="211"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="77"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF88853.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="363" mass="38837" checksum="0D91F9A4A8991F57" modified="2007-12-04" version="1">MTQSTLRLVEGSSMDKTKALDAALSQIERHFGKGSIMRLGKSGKVMEVESISSGSLGLDIALGIGGLPKGRIVEIYGPESSGKTTLALHTIAEAQKKGGTCAFIDAEHALDPIYARKLGVNLDDLLISQPDAGEQALEIADTLVRSGAIDVLVVDSVAALTPRAELDGEMGDNQPGMQARLMSQALRKLTASISKSNTMVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRIGMIKERDEVVGNQTRVKVVKNKLAPPFKQVEFDIMYGEGVSKMGELLDLGVRAGVVEKSGAWFSYDSQRLGQGRENAKTFLRQNPEVAGRIEATIRQNAGLIADQILTGSPEDEDGDGDAAAEA</sequence>
</entry>
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    <accession>A8IDA9</accession>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF88902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="STRING" id="438753.AZC_2904"/>
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        <property type="gene ID" value="AZC_2904"/>
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        <location>
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        <location>
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    </evidence>
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    </evidence>
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            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
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</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
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    </comment>
    <dbReference type="EMBL" id="AP009384">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF89461.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="249" mass="26691" checksum="38FC16AC438BD658" modified="2007-12-04" version="1">MDYLVQLASDPAAWIALVTLVAMEVVLGIDNLVFISILTNKLPEHQRSRGRRIGIGLALVLRLGLLSTVAIIVKLTTPVFSVFGQSFSWRDLILIAGGLFLVWKATKEIHHHVDPNPGEGVFETGKAAITFSAAIVQILILDLVFSIDSIITAVGMTEHIPIMVIAVIVAVLTMLLAADPLGRFIDANPTVVMLALAFLIMIGMTLIAEGFGAHVPKGYIYAAMAFSTAVEGLNMLSRRAKARRGGAGH</sequence>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <evidence type="ECO:0000259" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="163" mass="17597" checksum="4D8FA8FE85D9B1DA" modified="2007-12-04" version="1">MREADVPALAAMRRDDELQAQLLTVADALDDNAMAAWIERRTGEPGGAFQVVADARSEAFLGFVQVSHVHRRNRVGQGGLALASHARGQGFGHEAMALLLDYAARRLGLTKLMAEIRADNAASLRVHHAAGYRTVGLMTGHFHGRDGVHDVALLERHLGDMAS</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <text evidence="5">Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.</text>
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            <text>coproporphyrinogen III + 2 H(+) + O2 = 2 CO2 + 2 H2O + protoporphyrinogen IX</text>
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            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
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    <comment type="cofactor">
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            <name>a divalent metal cation</name>
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        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.</text>
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        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
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        <property type="project" value="UniProtKB-UniRule"/>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="133"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Important for dimerization" evidence="5">
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            <begin position="264"/>
            <end position="299"/>
        </location>
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    <feature type="region of interest" description="Substrate binding" evidence="5">
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            <end position="284"/>
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    <feature type="active site" description="Proton donor" evidence="5">
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        </location>
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            <position position="117"/>
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        <ligand>
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        <ligand>
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        </ligand>
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        <ligand>
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        <ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00333"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF89501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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</entry>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3523"/>
    <dbReference type="EnsemblBacteria" id="BAF89521">
        <property type="protein sequence ID" value="BAF89521"/>
        <property type="gene ID" value="AZC_3523"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3523"/>
    <dbReference type="HOGENOM" id="CLU_1329717_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF89521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="206" mass="22582" checksum="ED2DEB8387BB16C5" modified="2007-12-04" version="1">MRMEGISTRRVVQCVVVVAVAMAAAGFVRGIPATADGWIDFSGSVICGLFTVLAGALIWKAARHQSEISLQELIATDEFHFRRDRITSADFAARTQEAKTLVHSARLEVEANASSEAIGTLALDVEHALLPIICVENKFLRYVMRYDLDRLAWLASAIRHEGSAPDGKKTSLARILAECERLLNGIDAKTRRLTQIASPSMLKYAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IET5</accession>
    <name>A8IET5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histone acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpa2</name>
        <name evidence="2" type="ordered locus">AZC_3533</name>
    </gene>
    <organism evidence="2 3">
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        <lineage>
            <taxon>Bacteria</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <dbReference type="EnsemblBacteria" id="BAF86121">
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    <dbReference type="eggNOG" id="COG1152">
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    <dbReference type="InterPro" id="IPR017896">
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        <property type="entry name" value="Beta-grasp_dom_sf"/>
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        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Fer4_9"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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    </evidence>
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        <source>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
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    <sequence length="272" mass="29164" checksum="9AB5340918D380DA" modified="2007-12-04" version="1">MRGVGAARSRSGLYWHAPCCPERVIAARAIPRRGAPCRPQHAGPPRDPRRKFTVRETVHLTIDGCEVAADPTQSILQAYARSGAELTANVGCLGQGVCGSCRCLIRKDQERQVSTALACETRVEAGMQVSFIDHFLPAHVHRYDLSDIRDSWGLLGQIRAVFPEAAYCRHCSGCDRACPKGLPVQSGVASAVAGDLAAAAAVFDPCVMCNLCTLACPENIRPNHLGLFVRRAIAALTLRPVDLMRRLRDIETGAMTVEGPQPATASGEPAEG</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0139"/>
    <dbReference type="EnsemblBacteria" id="BAF86137">
        <property type="protein sequence ID" value="BAF86137"/>
        <property type="gene ID" value="AZC_0139"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0139"/>
    <dbReference type="eggNOG" id="COG2233">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_017959_8_3_5"/>
    <dbReference type="OMA" id="RINDAAW"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
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        <location>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="600" mass="62922" checksum="5F8623BC408D91B7" modified="2007-12-04" version="1">MTPVPGASPAKRPQGLLNRLRRLVMLEHGTPHRPRRRPPALVFGLEDKVPAGALIALSGQHAMLALTFLIYPLVAASQVGLSQPETNAVLTACTLCIGIATMLQCARSRVGSGYLIVHVPSPGALPLAIQALTLGGVGLMAAMTLLVGVSQLFIARIVRPLRVLLPPEVCGVAVTTLGISLAEPALRRALGLDRGSSVVDDNALIVSLVTVALIVGIAIFTPRRIKIFAVLIGASSGWALAAWLGIEQPGGAALLASAPLVALPSLHLPAFEIAPSLLPLAALSVMLNIVDVLSITVSLEKMNDAEWRRADMRAASRAVTTSGIGNVLNGLVSGFQSGLSSSAVGLAFATGATARIIGFVAGALIFATAFFPKAIVALTLIPAPVVGGILIYTTAYLLVAGMELILSRRLSERRVFLVGLSILAALSVALLPIKGQFPGWIQPLVSTPMSVGAFCAIVLNLIFRIGISQESGFTAGLGTDPYPTMRDFLERQGDLWGARRDVIAAAIPVGAQALELLLENSIATGEVEVRARFDETHLDVFLLYDGAVLEPPKARPSPEALLGDDAEVAAFCAYMIQKLSDHVTFGQSSGRARIALRFDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGZ4</accession>
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            <fullName evidence="2">Uncharacterized protein</fullName>
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    </protein>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0154"/>
    <dbReference type="EnsemblBacteria" id="BAF86152">
        <property type="protein sequence ID" value="BAF86152"/>
        <property type="gene ID" value="AZC_0154"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0154"/>
    <dbReference type="eggNOG" id="COG2755">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_065317_1_1_5"/>
    <dbReference type="OMA" id="HATRAIT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721015" evidence="1">
        <location>
            <begin position="24"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="261" mass="28092" checksum="3A1528416CEE51EE" modified="2007-12-04" version="1">MIRRVGPWMIALALACLTPGTLAAQPAAPAASAVRACPAPDRYLTPKVPLRRAAEAVRKGKRLRVLVFAAVRMPAITETVEAKRYPASLAAALSQRLPGVDVTVTTRMEPRAGAGESLPLLNAALSAPVAPSGYDLVIWQLGSTDVLKGTDMSAFGTKLSSGVQAIHARQADAIVITMQYSPRTDFMFDAGPYLQALRWTVKSEGAALFNRYDIMRYWAEEGTFDLSDLQPGASMFEDVHRCVGDLLARFITNGMAAPETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH16</accession>
    <name>A8IH16_AZOC5</name>
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        <recommendedName>
            <fullName evidence="4 5">UTP--glucose-1-phosphate uridylyltransferase</fullName>
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        <alternativeName>
            <fullName evidence="5">UDP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_0162</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UDPGP type 2 family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="3 5"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0162"/>
    <dbReference type="EnsemblBacteria" id="BAF86160">
        <property type="protein sequence ID" value="BAF86160"/>
        <property type="gene ID" value="AZC_0162"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0162"/>
    <dbReference type="eggNOG" id="COG1210">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029499_1_2_5"/>
    <dbReference type="OMA" id="MHYVRQG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02541">
        <property type="entry name" value="UGPase_prokaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005771">
        <property type="entry name" value="GalU_uridylyltTrfase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43197">
        <property type="entry name" value="PTHR43197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01099">
        <property type="entry name" value="galU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="45"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF86160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="332" mass="36448" checksum="022406AF2D3940D7" modified="2007-12-04" version="1">MLKFCNQFRAIALLCEHPVSCVRKPGFSILGNKERGVMPKPLRKAILPVAGLGTRFLPATKAVPKEMLTVVDRPVVQHVVDEAVAAGIEHIVFVTGRNKAVIEDHFDRQFELEKTLADRGKTKELAQLDRDTPKAGTTSFTRQQLPLGLGHAVWCARDLIGDEPFALLLPDMLHLPNGNGKGCLTEMVETYNKTGGNVISVYEVPDDQTNQYGIVGLGKETSAKAHEITQMVEKPAAGTAPSNLAISGRYILQPTIFDLLAKQEQGAGNEIQLTDSMLKLMERERFFSVRFDGSVYDCGSKIGFLMANVAYALSRPDIAPEFRTELGHFLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH63</accession>
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            <fullName evidence="7">Putative transporter</fullName>
        </submittedName>
    </protein>
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        <name evidence="7" type="ordered locus">AZC_0178</name>
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    <organism evidence="7 8">
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        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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                <person name="Lee KB."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu CT."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Lee KB."/>
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            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    <evidence type="ECO:0000256" key="1">
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    <sequence length="371" mass="40407" checksum="C6DF8E97C5BEDA04" modified="2007-12-04" version="1">MYVAVKGGETAIRNAHALLAETRRGDTSVPEIGIDQIAGQLTLAVDRVMSEGSLYDRPLAALAIKQARGDLIEAIFLVRAFRTTLPRFGYSEPVDTGRMRVERRISATYKDIPGGQVLGPTFDYTHRLLDPTLATTGGAAGAPKGQPARADGAAEPGPMPRVTDLLGDEGLIEPAPATGEEPRDLTREPLSFPADRPLRLQNLARGDEGFLLSLGYSTQRGYARSHPFVGEIRFGTVEVELFVEELGFAVPLGDIALTECQMVNQFKGSASEPPKFTRGYGLVFGQSERKAMSVALVDRALRFKELGEEQSAPAQDEEFVLSHSDNVQATGFVEHLKLPHYVDFQAELDLVRRMRAEHADGTETSQQEAAE</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
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                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Binnewies T."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C59 family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="MEROPS" id="C59.001"/>
    <dbReference type="EnsemblBacteria" id="BAF86209">
        <property type="protein sequence ID" value="BAF86209"/>
        <property type="gene ID" value="AZC_0211"/>
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    <dbReference type="eggNOG" id="COG3049">
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    <keyword evidence="3" id="KW-0732">Signal</keyword>
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        <location>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006625"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02275"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86209.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="372" mass="39968" checksum="2E255205A7A59F64" modified="2007-12-04" version="1">MRTRRNPMLRTLTTALSLAAMMNAALACTAVDIVAADRTVIAGRTMEWAFDMKWTLVSRPKGFPVKLTAPKALNLPERTVEAKYALVGVSANIIPGGALVEGQNAAGLGMSGNFLPGFTTYQTVTPQDKNYVEVLSFGAWALGNFATIAEVKEALKTTKVWSDPSAASGPTAPLMHFVFTDRAGASIIVEYVEGELHIHDNVAHVLTNAPTYDWHLTNLRNYLNLSTVGVEQRQIGNVDVTALGQGGGLVGLPGDYTPPSRFVRASALRHGMTPPKDGAEAVQAVVHVLNTVDIPVGVAQSRLPNGQLVSDYTQWVSIKDLTNNRLQIADYAHRTSYLTIDLAPLFALDKPAERLITDLPYPAGVGADVLKP</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="CAZy" id="GH103">
        <property type="family name" value="Glycoside Hydrolase Family 103"/>
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        <property type="protein sequence ID" value="BAF86270"/>
        <property type="gene ID" value="AZC_0272"/>
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        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
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        <property type="entry name" value="MltB-like"/>
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        <property type="entry name" value="MltB_2"/>
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        <property type="entry name" value="Peptidoglycan-bd-like"/>
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        <property type="entry name" value="PGBD-like_sf"/>
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    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
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        <property type="entry name" value="SLT_2"/>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="46"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="1">
        <location>
            <begin position="368"/>
            <end position="422"/>
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    <evidence type="ECO:0000259" key="1">
        <source>
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    <evidence type="ECO:0000259" key="2">
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            <dbReference type="Pfam" id="PF13406"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
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    </evidence>
    <sequence length="426" mass="46618" checksum="1AA4ABE4844F9994" modified="2007-12-04" version="1">MLASGRRDREIRSVNGKLHLFLRGLLGTLALLVLAAPAPARADAAFTQFIASLWPEAQAAGVSRETFERETRGLEPDYKLPDLALPGRPATGAGKQAEFVQVPADYVREATIERLAAEGRRLMQKYQPVLAQIERQFGVPGPVVLAIWGRETDFGRYTEPHDALRVMATQAYAGRRKAQYRTEFILALKILDEGVVPRKAFRASWAGATGLTQFLPSDYFAHGVSLEGNAHPDIWRSVPDALASAAKQLADKGWQPGLRWAYEVRAPANADCTLGVPEVQRPIGDWVRAGFQPIGVRLSAAELAQPASLLQPEGIYGPSFLTTKNYFVIKEYNFSDLYVLFVGHLSDRMTNPQPFATPWAASTQLRTSSVEAMQKHLARLGLYGDKIDGKAGMLTRAAVGAYQKSAGLKVDCWPSEGVLQSMGAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="37" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
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                <person name="Roe B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="16 17" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16 17" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
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            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
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            <name>FAD</name>
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        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
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    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
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    <dbReference type="EnsemblBacteria" id="BAF90007">
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    <dbReference type="eggNOG" id="COG1249">
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    <dbReference type="HOGENOM" id="CLU_016755_0_3_5"/>
    <dbReference type="OMA" id="DAKYGEW"/>
    <dbReference type="OrthoDB" id="267896at2"/>
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        <property type="project" value="InterPro"/>
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        <property type="entry name" value="Lipoamide_DH"/>
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        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
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        <property type="entry name" value="PYRIDINE_REDOX_1"/>
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    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
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    <keyword evidence="6 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
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    <feature type="binding site" evidence="11">
        <location>
            <position position="51"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="115"/>
        </location>
        <ligand>
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            <end position="146"/>
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        <ligand>
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    <feature type="binding site" evidence="11">
        <location>
            <begin position="181"/>
            <end position="188"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
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    <feature type="binding site" evidence="11">
        <location>
            <position position="204"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
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    <feature type="binding site" evidence="11">
        <location>
            <position position="273"/>
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        <ligand>
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            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="314"/>
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        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="320"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
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            <begin position="42"/>
            <end position="47"/>
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            <dbReference type="ARBA" id="ARBA00001492"/>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
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            <dbReference type="ARBA" id="ARBA00023284"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="13">
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            <dbReference type="RuleBase" id="RU003692"/>
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    <evidence type="ECO:0000259" key="14">
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            <dbReference type="EMBL" id="BAF90007.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="467" mass="48690" checksum="31F2A544487D03BC" modified="2007-12-04" version="1">MANYDLIVIGTGPGGYVAAIRAAQLGLKTAVVEKRATHGGTCLNVGCIPSKALLFASEKFEEAGHSFASMGITVPAPKLDLAAMQAFKDKGVDGNVKGVEFLLKKNKVDAYHGVGKILAPGKVEVTAADGTQQVLETKNILIATGSDVAQLPGVTIDEEKVVSSTGALALKRVPGKLVVVGAGVIGLELGSVWRRLGAEVTVVEYLDRILPGMDGDVAKSFQRILQKQGFAFKLGTKVTGVDTKGKTLKVSVEPAAGGAAEVLEADVVLVAIGRVAYTGGLGLAEIGVETDKRGRVVVDHHYKSTVDGIYAIGDVIAGPMLAHKAEDEGVAVAELLAGKAGHVNYDVIPGVVYTFPEVASVGKTEEELKEAGIAYNVGKFPFTANGRAKVNNTTDGFVKFLADAATDKVLGCHIIGPEAGEMIHEVCVLMEFGGSSEDLARTCHAHPTRSEAVKEAAMAVEKRAIHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="47" xmlns="http://uniprot.org/uniprot">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0409"/>
    <dbReference type="EnsemblBacteria" id="BAF86407">
        <property type="protein sequence ID" value="BAF86407"/>
        <property type="gene ID" value="AZC_0409"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0409"/>
    <dbReference type="eggNOG" id="ENOG503025D">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_207916_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021446">
        <property type="entry name" value="DUF3096"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11295">
        <property type="entry name" value="DUF3096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="46" mass="4991" checksum="2A22AC2A4D193FBE" modified="2007-12-04" version="1">MTFDLVIIQPIVALIAGILILLFPRLLNVLVAIYLIVVGILGLVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>A8ILW0</accession>
    <name>A8ILW0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">COX4_pro_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168960.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0429"/>
    <dbReference type="EnsemblBacteria" id="BAF86427">
        <property type="protein sequence ID" value="BAF86427"/>
        <property type="gene ID" value="AZC_0429"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0429"/>
    <dbReference type="eggNOG" id="ENOG502ZFIZ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_174805_1_0_5"/>
    <dbReference type="OMA" id="PAHENTY"/>
    <dbReference type="OrthoDB" id="1971875at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036596">
        <property type="entry name" value="Cyt-C_aa3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012422">
        <property type="entry name" value="Cyt_c_oxidase_su4_bac-aa3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07835">
        <property type="entry name" value="COX4_pro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81469">
        <property type="entry name" value="SSF81469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="COX4_pro_2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="50" mass="5638" checksum="246860548E5DFA3B" modified="2007-12-04" version="1">MSEHGAIEYATADGNDYAEHKRTYELFTALTKWGTVAVAALMVIMWFTLL</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMK0</accession>
    <name>SYL_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="1">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">leuS</name>
        <name type="ordered locus">AZC_0567</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169098.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IMK0"/>
    <dbReference type="SMR" id="A8IMK0"/>
    <dbReference type="STRING" id="438753.AZC_0567"/>
    <dbReference type="EnsemblBacteria" id="BAF86565">
        <property type="protein sequence ID" value="BAF86565"/>
        <property type="gene ID" value="AZC_0567"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0567"/>
    <dbReference type="eggNOG" id="COG0495">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_004427_0_0_5"/>
    <dbReference type="OMA" id="TFMVLAP"/>
    <dbReference type="OrthoDB" id="32262at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword id="KW-0067">ATP-binding</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-0436">Ligase</keyword>
    <keyword id="KW-0547">Nucleotide-binding</keyword>
    <keyword id="KW-0648">Protein biosynthesis</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_1000071108" description="Leucine--tRNA ligase">
        <location>
            <begin position="1"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="614"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region">
        <location>
            <begin position="627"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="630"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <sequence length="874" mass="97619" checksum="B7DC946BFD5677C8" modified="2007-12-04" version="1">MSTDRYNARDAEPRWQAIWNERGIFRTRNDDPRPKFFVMEMFPYPSGRIHIGHGRNYVMGDVLARYKRMQGFNVLHPMGWDSFGLPAENAAIERGIHPKSWTYENIASMKEQLQLLGLSLDWNREVATCDPSYYAEQQRLFLDLFENDLAYRKESEVNWDPVDNTVLANEQVIDGRGWRSGAVVERRKLNQWFFRITAFAQELLDAIDTLDRWPDKVRLMQRNWIGRSEGLEVLFELSKGSVAAAGTSAVKVYTTRPDTLFGASFLALSPDHPLTQHLAATRPDLAAFVADCKTGGTSAEAIETQEKKGFDTGLTVVHPLDAARTVPVYVANFVLMDYGTGAIFGCPAHDQRDLDFARKYGLTVTPVVLPPGADPAVFAVGSEAYDGEGTLYNSQFLDGLSIADAKEQVARRLERFRVGEQPQGTRKVNFRLRDWGISRQRYWGCPIPIIHCDSCGPVAVPREQLPVELPDDVTFDRPGNPLDRAKAWRDVPCPKCGAPARRETDTMDTFVDSSWYFLRYASDNPDKPLDKDAVRHWLPVDQYIGGIEHAILHLLYSRFFTRALKACGRVDVAEPFAGLFTQGMIVHETYKDKDGRWLFPEEVKLLGDGKAEKLDDGSPVTVGPPEKMSKSKKNVVPPEVVVDTYGVDAGRWFMLSDTPPERDSEWTQSGIEGAWRFVQRVWRQVQEAIELGAPKGADKPASFDAAATALRRAAHGLAHQVADDVERLRFNVAVAHVHEFANAFGQAIASARTASPVPADLAFALREAAEIVTRVVGPMVPHLAEECWAALGYDTLLAEAAWPKAEPELLVENTITLPIQINGKKRDDITVPRDATAAEVEAAVLEMESVRRALDGKAPKRIIVVPQRIVNVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMN4</accession>
    <name>A8IMN4_AZOC5</name>
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        <submittedName>
            <fullName evidence="13">Cytochrome d ubiquinol oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cydA</name>
        <name evidence="13" type="ordered locus">AZC_0584</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the cytochrome ubiquinol oxidase subunit 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169115.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0584"/>
    <dbReference type="EnsemblBacteria" id="BAF86582">
        <property type="protein sequence ID" value="BAF86582"/>
        <property type="gene ID" value="AZC_0584"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0584"/>
    <dbReference type="eggNOG" id="COG1271">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030555_3_1_5"/>
    <dbReference type="OMA" id="FLINIAM"/>
    <dbReference type="OrthoDB" id="271551at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070069">
        <property type="term" value="C:cytochrome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002585">
        <property type="entry name" value="Cyt-d_ubiquinol_oxidase_su_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30365">
        <property type="entry name" value="PTHR30365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01654">
        <property type="entry name" value="Cyt_bd_oxida_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006446">
        <property type="entry name" value="Cyt_quinol_oxidase_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 12" id="KW-0349">Heme</keyword>
    <keyword evidence="10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="129"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="185"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="392"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="426"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="468"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR006446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF86582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="524" mass="57835" checksum="FDEF4C31D1AD70E9" modified="2007-12-04" version="1">MEFDIVSLSRLQFAMTALYHFLFVPLTLGLSIIVAIMETVYVMTGRTIWRQMTKFWGTLFGINFVLGVATGLVMEFQFGMNWSYYSHYVGDIFGAPLAIEGLMAFFLEATFVGLFFFGWDRMSKVGHLVATWAVAFGSNFSALWILIANGWMQNPVGAVFNPQTMRMEVDDFYAVLFNPVAQAKFVHTVSAGYTTASVFVLGVSAWYLLKGRHIELAKRSMTVAASFGLAAALSVVVLGDESGYLTTEHQKMKLAAMEAIWRTEPVPAPFTVVGFPDQKARETHYAVEIPWVGGLIDTRSLNTPVEGIEELVERAKGNIAKGVLAYDALQKIRAAGSAAVPVDVQKTFEANGNLLGYALLLKRYVDDPRQATPEQIAKAAWDTVPQVAPLFWTFRIMVGVGFFMILLMATFFTLSARRQLDRFPLLLRIAVLAIPLPWLAAECGWFVAEFGRQPWIIEGILPTASAVSSLGAMTVLLTIAGFVLIYTTLFIIEMGLMLRAIRKGPAPDNEPEAELIPATVVPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IMS7</accession>
    <name>A8IMS7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrogenase expression/formation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hupG</name>
        <name evidence="1" type="ordered locus">AZC_0603</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Peripheral membrane protein</topology>
            <orientation evidence="8">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169172.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0641"/>
    <dbReference type="EnsemblBacteria" id="BAF86639">
        <property type="protein sequence ID" value="BAF86639"/>
        <property type="gene ID" value="AZC_0641"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0641"/>
    <dbReference type="eggNOG" id="COG1886">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_097058_5_0_5"/>
    <dbReference type="OMA" id="ESVMRIP"/>
    <dbReference type="OrthoDB" id="1875967at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012826">
        <property type="entry name" value="FliN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02480">
        <property type="entry name" value="fliN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="6 8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="9">
        <location>
            <begin position="39"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="120" mass="12691" checksum="9F69607A711620A0" modified="2007-12-04" version="1">MAPPDDFDKDTAQDEALFSKALKDNGKEETIGTGQGLESVMRIPVLLQVVLGSASMPVANLMKLGRGAIVPLDHRVGEPVDVVVNGRIIARGEVMVVEEDNSRFGVTLTEIVGPGGADHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPL0</accession>
    <name>A8IPL0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar motor switch protein FliM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fliM</name>
        <name evidence="13" type="ordered locus">AZC_0643</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="14" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="13 14" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FliM family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169174.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0643"/>
    <dbReference type="EnsemblBacteria" id="BAF86641">
        <property type="protein sequence ID" value="BAF86641"/>
        <property type="gene ID" value="AZC_0643"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0643"/>
    <dbReference type="eggNOG" id="COG1868">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_052646_2_0_5"/>
    <dbReference type="OMA" id="VITLMEH"/>
    <dbReference type="OrthoDB" id="1748746at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17908">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001689">
        <property type="entry name" value="Flag_FliM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02154">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="12">
        <location>
            <begin position="226"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="BAF86641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="309" mass="34934" checksum="DA5B6EB4BD80B68B" modified="2007-12-04" version="1">MNAAHSHQDIRDMLLDAAGLSIDRMPMLHVIFDRLGTLCAEGLRQLAASQAFYSLSSIETGRIGDVLEMYEGMAVAGVFHVPMWDSHIIVGFDRDFVFTMIEALFGADGSEPPVDDERSFSNIELRISQAIFEQMQKALHNAFTMVSDTQFKFERQETRMDFAVIGRRNNLAVTAKFLLQALNRGGEMFVIIPQSALTPMRQALARTTPAETSGRDPIWTKQIRDEVNRTQVKVRAILEERHYPLGEIADFKVGQVLHLQATPRTLVKLESADQPLFWCHLGQAEGAYVLRVEEQINLNQEFVDDILPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPP6</accession>
    <name>A8IPP6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Chemotaxis sensory transducer</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_0666</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0666"/>
    <dbReference type="EnsemblBacteria" id="BAF86664">
        <property type="protein sequence ID" value="BAF86664"/>
        <property type="gene ID" value="AZC_0666"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0666"/>
    <dbReference type="eggNOG" id="COG0840">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000445_21_4_5"/>
    <dbReference type="OMA" id="AMTITHI"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01068">
        <property type="entry name" value="globin_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044398">
        <property type="entry name" value="Globin-sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039379">
        <property type="entry name" value="Protoglobin_sensor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11563">
        <property type="entry name" value="Protoglobin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="241"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="5">
        <location>
            <begin position="400"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="504" mass="53882" checksum="F8DBF82431752413" modified="2007-12-04" version="1">MRLILPVDDARDAIFAKAWPYSMGRPLRKRCGRIGRVASFARPDREELAAPPRAAKRDGPMTQESLSQRLNFIGMDKALQASLREARDLVVAAMPKILDGFYDHLMTYPDMARMFPTAAVRAHAKAMQIKHWGVILDGRFDAAYVESVTRIGQTHARLGLEPRWYIAGYALLLSGLVAAIETGFKAGRFDRTAPERKARLIEAVITAALLDMDFAISVYLDAGIKAKRETLDRVGAAFRSIVTTVSDAAAHLETTAASLADTAQSTRALSSAVASSSEQASSNVQSVATASDELAASINEISRQVRESSRIAGEAVEQAQRTDERIRELSSASARIGDVLKLITAIAEQTNLLALNATIEAARAGEAGRGFAVVAQEVKALASQTAKAIEEIGGQITSMQSATQDSVSAVKEIGHTIERLAGISETIAHAVDSQTEATSMITANVARAAVGTEEVATAIASVRTQAVNTGSASEEVLGSARMLSSESQRLNEEVETFLKTIDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IPW1</accession>
    <name>A8IPW1_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_0705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169236.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0705"/>
    <dbReference type="EnsemblBacteria" id="BAF86703">
        <property type="protein sequence ID" value="BAF86703"/>
        <property type="gene ID" value="AZC_0705"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0705"/>
    <dbReference type="eggNOG" id="COG0110">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_051638_5_0_5"/>
    <dbReference type="OMA" id="VWCATIG"/>
    <dbReference type="OrthoDB" id="1878940at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017694">
        <property type="entry name" value="Phosphonate_tfrase_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03308">
        <property type="entry name" value="phn_thr-fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="211" mass="23445" checksum="2A3A8BC425CBCFCE" modified="2007-12-04" version="1">MKKLGLAPLIDPTASVKDSSLGRYTEVGARVKLLEVAMGDYSYIEHDSDMAYTQVGRFCSIAALTRINPGNHPMWRASQSHFTYRASTYFDDAQDEPDFFQWRRDHGVTLGHDIWVGHGAVILPGRTIGTGAVVAAGAVVTKDVPPYAIVAGVPARIVKWRFPETIAERLQALAWWDWDHGSLRAALEDFRALPVEGFLEKYERRAVSAAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-09-02" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQ73</accession>
    <name>RLMN_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="1">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rlmN</name>
        <name type="ordered locus">AZC_0752</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IQ73"/>
    <dbReference type="SMR" id="A8IQ73"/>
    <dbReference type="STRING" id="438753.AZC_0752"/>
    <dbReference type="PRIDE" id="A8IQ73"/>
    <dbReference type="EnsemblBacteria" id="BAF86750">
        <property type="protein sequence ID" value="BAF86750"/>
        <property type="gene ID" value="AZC_0752"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0752"/>
    <dbReference type="eggNOG" id="COG0820">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_029101_0_0_5"/>
    <dbReference type="OMA" id="QVGCSLD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0004">4Fe-4S</keyword>
    <keyword id="KW-0963">Cytoplasm</keyword>
    <keyword id="KW-1015">Disulfide bond</keyword>
    <keyword id="KW-0408">Iron</keyword>
    <keyword id="KW-0411">Iron-sulfur</keyword>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-0489">Methyltransferase</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0698">rRNA processing</keyword>
    <keyword id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword id="KW-0808">Transferase</keyword>
    <keyword id="KW-0819">tRNA processing</keyword>
    <feature type="chain" id="PRO_0000350024" description="Dual-specificity RNA methyltransferase RlmN">
        <location>
            <begin position="1"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="127"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="1">
        <location>
            <position position="380"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="206"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="(transient)" evidence="1">
        <location>
            <begin position="134"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000255" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01266"/>
        </source>
    </evidence>
    <sequence length="406" mass="44486" checksum="62AC38DB61A5DA02" modified="2007-12-04" version="1">MYAPMMPSPTAVAAPVAALSILPSLAGLDREKLGLALAAIGVPERERKMRVNQLWHWIYLRGATDFAEMTNVSKTLRTQLAEHYSLARPEIVVEQVSQDGTRKWLLRLPAETPGERPHEVEAVYIPERDRGTLCVSSQVGCTLNCAFCHTGTQRLVRNLTAAEIVAQVLVARDRLGDYPGRERAVGPGLPTEGDRLVTNIVFMGMGEPLYAYDSVAEAIEILADGDGLGLGKRRITVSTSGVVPEIEKLGREVGPMLAISLHAVRDDLRDVLVPINKKYPIAELMEACRTYPAASNAKRITFEYVMLKGVNDSPADARALVKLLEGVPAKINLIPFNPWPGTKYECSDWETIEKFSDIVFRAGYASPVRTPRGRDILAACGQLKSETEKLSARERLALRAMAAAAE</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2011-01-11" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IQD2</accession>
    <name>AHLLM_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acyl homoserine lactonase AttM</fullName>
            <shortName evidence="2">AHL-lactonase AttM</shortName>
            <ecNumber>3.1.1.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">attM</name>
        <name type="ordered locus">AZC_0767</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>an N-acyl-L-homoserine lactone + H2O = an N-acyl-L-homoserine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55474"/>
            <dbReference type="ChEBI" id="CHEBI:58921"/>
            <dbReference type="EC" id="3.1.1.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-beta-lactamase superfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.81"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169298.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IQD2"/>
    <dbReference type="SMR" id="A8IQD2"/>
    <dbReference type="EnsemblBacteria" id="BAF86765">
        <property type="protein sequence ID" value="BAF86765"/>
        <property type="gene ID" value="AZC_0767"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0767"/>
    <dbReference type="eggNOG" id="COG0491">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030571_3_2_5"/>
    <dbReference type="OMA" id="HEEEFKH"/>
    <dbReference type="OrthoDB" id="1815576at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102007">
        <property type="term" value="F:acyl-L-homoserine-lactone lactonohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
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                <person name="Liu CT."/>
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                <person name="Aono T."/>
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                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="1 2" key="5">
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="98" mass="11082" checksum="0E2CA25052E6D54B" modified="2007-12-04" version="1">MEIGETQVKPLASTFLNIIGDEITWGQIVALFAGSGLKWDGAAFFAQFDPDGPLENEDARARLREVESRVREDRLVLNEGQFFDAWGRRLQIEEINLS</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <property type="protein sequence ID" value="BAF87186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <property type="gene ID" value="AZC_1188"/>
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        <property type="entry name" value="CoA_transf_3"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
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            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="457" mass="48526" checksum="F03E55E9539A8788" modified="2007-12-04" version="1">MSPSPTFTAALSEIWTALGGAHADSAAVRLSGAGRLSSAFPVSDLAAASVAAAGLALGTLRAQGDPLPEIAVDSRLASLWFSTSYRPEGWPVPPVWDAVAGDYRTADGWIRLHTNAPHHRAAALSVLCTPADREAVAAAVARWTGEDLEAAIVAANGCAAVMRTQEEWAVHPQGAAVAREPLIWRTEGTASDRPEARLDPVRPLAGVRVLDLTRVLAGPTATRVLAGFGADVLRIDPPFWDEPAVLPDMTLGKRRAHLDLREAEDRQQLAVLLSEADILVHGYRSDALEAMGFGAEARQDIRPGLVDVSLDAYGWTGPWAQRRGFDSLVQMSSGIAHAGMVHYGKDRPTPLPVQALDHATGYLLAAAALRGLAQRREAGRGSLWRTSLARTARLLVDLPAATGEAPLAPAEEADFAPGLEQSAWGPLHRLKPPLRIEGTPMAWDHPAGLLGVDAPLW</sequence>
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    <organism evidence="7 8">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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        <location>
            <begin position="37"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="211"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="354" mass="37663" checksum="0F2FDF812FA06D86" modified="2007-12-04" version="1">MPFIWLAYFFPLAALALGLAVSVLPVPFTGGLSFIETVLLIGTSFAAVHHAEGISSRIGQPFGTLILTLSVTVIEVSVLVAMMLNGENNPGVGREAVLSTVMFVCTGVVGACLLVGALRHREQEVRQQGVNGYLSVIIAISVLCLLLPQNTHAGLMGAVDPFQISFIMCGTVVLYGAFLFMQTVRHRADFMPEASEPAPARPRRLVVHIPLLLAALGGIVLVSSGVAAGVEELLDRLHLRDPDAVISAAVVAMLLLPETITAIRAARANDLQRSINTALGSALATIGLTMPAMVAISVWVDRPIYLGIEPEDRVQLLLVLVLSIVSFGTGRTNLLNGFVHLVLFAIYVMTLFVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRY0</accession>
    <name>A8HRY0_AZOC5</name>
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        <submittedName>
            <fullName evidence="6">Putative decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4111</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the group II decarboxylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4111"/>
    <dbReference type="EnsemblBacteria" id="BAF90109">
        <property type="protein sequence ID" value="BAF90109"/>
        <property type="gene ID" value="AZC_4111"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4111"/>
    <dbReference type="eggNOG" id="COG0076">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011856_0_4_5"/>
    <dbReference type="OMA" id="NPGFNWS"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="489" mass="51939" checksum="70AB02D7468A58B3" modified="2007-12-04" version="1">METPMREPTLDPADWSALRAVFHQAVDDGLAHLQGALDTPVWVAPPGSSKSALYEPLPRTATPAAEVYETFRNHVLPYGVGNVRPAFYGWVHGAGNAEGVLGELMAAFMNCNVGGRAHMANELERVVVDWCKDFTGLPAEASGLLTSGTSMATVLAIATARHVHADGDVGREGVAVAGRGLVGYASTEAHSCIAKAFDLLGLGRNALRAVPVNTAREMDSAALEAMIATDRAAGLKPFMVAATVGTVNTGAIDDIAGIGAIAHREGLWFHVDAAFGIGALFSDAHKAKAAPMARAESIAFDFHKWFQVPYDAGIVLIRDAKAHYETFAGRKEYLASSERGLAAGEPWYCDYGPELSRTFRALKVWFTLKSHGVDGISAIIAKNIAQARYLEDKVAAEPRLELLSPASLNIVCFRYVAPCDTAALNQLNKDIVADLQEAGIAAPSTTTLNGRTAIRVCLANHRTRRQDLDALLAGVLELGARRTAGSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="44" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSB6</accession>
    <name>A8HSB6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4163</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="BAF90161">
        <property type="protein sequence ID" value="BAF90161"/>
        <property type="gene ID" value="AZC_4163"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4163"/>
    <dbReference type="eggNOG" id="COG0803">
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    <dbReference type="HOGENOM" id="CLU_008448_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720667" evidence="2">
        <location>
            <begin position="31"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="657"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="657"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="714"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
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            <begin position="756"/>
            <end position="818"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="838"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="851"/>
            <end position="881"/>
        </location>
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        <location>
            <begin position="892"/>
            <end position="1021"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
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            <begin position="1066"/>
            <end position="1140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1141"/>
            <end position="1161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1161" mass="117769" checksum="41A92EDAA2F37E62" modified="2007-12-04" version="1">MRVAMYARRSVLPALLLAATSLLSPAHLQAQSPAPAAQAQAVQPAWPRIYRWDDTTLRLYAPQVVHRRDGAVRARAAFALTIKDGTTHYGRVAFYARTRTDYATGTLRLRDLAVERVEFPAAPRRADDLAIQLTLQLSGQHITLPLALVQAELDAAAHPPERLPGVTAPPAIIFTDRLTTLVSIAGAPVLRPVPGADGFQRVINTPALILQDVAGTLHLRAAGTWFEGTSLTGPWTPAPEVPPDVSTAAAAAEAVQPADPLLPPNGQPLSPPPALLVATTPTDVIQTDGPARWEAVAGTALQTIGNADQAVFLSPDTETYYVLLAGRWFAAPALSGPWRGIAGTALPRAFAHIAPTDPKANVLISVPGTPQAREAAIAASIPQVAEVPRSTTATVAYDGAPQFASIPGTGLSYAVNSPEPVIRTGTGASYLLSKGVWFAAPAPSGPWTVADAVPPAIYAIPPASPVHYVTGVRIYGARDGAVSVGYTPAYMGVGLGSGDTVVYGSGVASPGYVGTRWTPAPSTYGVGAGFSLGTSGFGYGFSPGWSWGAGAGPHWGPYAGATPYGRGWGFANAAGADIYGRWGGGVSVGAGWGGSAGTGVWSHGAWGGFGAGGAGGGFATGFGAGFGAGGFSAYGGHYMSNTYNSHVTTNATTINNQTINNTTNTNTSNTTTNSTSTTTGGASGSTNAGGSSGSTTGSSSSSASGSSSGSDGKDNTSGHDDHGHGRTGRDGKDGRDGRDGRHEGRDRDGHQDRDGTGAGSSGSSGTSNGSGSSGSSNSSGSSNSGGASGASGSSGSSGSSGSSGPSSNSSSGSGNSPDSGHDDHGGGKDGRDGDGKGGHQGGGDNPADHVNGTTMPDQNKDSRSGGDSSADRVNGTTMPDQGKDSRGGGDNSADRVNGTTMPDQNKDSRSGGDSSADRVNGTTMPDQDKDSRGGANSSADRVNGTTMPDQNKDSRSGGNNSADRINGTTMPDQDKDSRSGGNSSADRVNGTTMPDQGKDSRSGGDNSADRVNGTTMPDQGKDSRSGDADKASNSSGVTTHPDSTGGKADKDRKGAGGTGGNPADDRINGTKRDDDASKDRPHATDDAQRGDHDRGGDHRDGEHRTDGDHHEGDHKDGEHRDGDHKDGDHHEGDHKDGDHHKHRSGGHHRSGHHSGGHHGRR</sequence>
</entry>
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    <name>A8HSC9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_4168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4168"/>
    <dbReference type="CAZy" id="GT4">
        <property type="family name" value="Glycosyltransferase Family 4"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF90166">
        <property type="protein sequence ID" value="BAF90166"/>
        <property type="gene ID" value="AZC_4168"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4168"/>
    <dbReference type="eggNOG" id="COG0438">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009583_16_0_5"/>
    <dbReference type="OMA" id="IFTMSEA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="31"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="164"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="352" mass="35851" checksum="F3C01CAEFE099B13" modified="2007-12-04" version="1">MMKAVLAFPGDLDTPTGGYAYDRAVLRALPGHGVDVKPLALPRAFPFPAASDLAETARLLGETPADALLFVDGLALGAMPVDLLNASGRRIVALIHHPLAREAGLSPEQQAALEASEREALAICAGVIATSAATGRDLVANYGVPPDRLSIAEPGVAPAPRAVAQGEPPHILAIGSVIPRKNYAGLVAALAGVADLGWTATFIGSLDFAPQTVAEVRSLIAAHGLGHRIRLAGAVPAEALEAAYAGCDLFVHAALYEGYGMVLADALRRGLPMIASTGGAAGDTVPDGSAVKVPPGDTPALTAALRALLSDRSARLRLADAAAEAGARLPGWDDTARTIAQALKQASRSPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSR9</accession>
    <name>A8HSR9_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Putative ABC-type sugar transport systems permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_4210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <subcellularLocation>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
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        <property type="protein sequence ID" value="BAF90208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="MetI-like_sf"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="ABC_TM1"/>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
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        <location>
            <begin position="86"/>
            <end position="105"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="140"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <end position="260"/>
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    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="303"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="145"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF90208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="374" mass="41359" checksum="F3D533BD41B039FD" modified="2007-12-04" version="1">MFPRRAAAAVTGKAHGGRPPRAAALFRVFRLGPERFRSPPSPARRDETPPQAALRRFRFMADIAAHRASPSPFQSWLSRVGQGRHLLGLMFLLPAAVFLLFFLTYPLGLGVWLGFTDTRIGRDGVFIGLENYEMLFGDSLFWLAVFNTVLYTVGASILKFALGLWLALLLNQNLPFKSFFRAVVLLPWVVPTVLSAIAFWWIFDAQFSVISWALIKIGLIDHNINFLGDTTNARASVIAANVWRGIPFVAISLLAGLQTIPQSLHEAATLDGATGWQRFRYITLPMLSPIIAVVMTFSVLFTFTDFQLIYVLTRGGPLNATHLMATLSFQRAIPGGQLGEGAAIAVAMIPFLLSAILFSYFGLQRRKWQQGGGD</sequence>
</entry>
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        <submittedName>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the C/M/P thioester hydrolase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4228"/>
    <dbReference type="EnsemblBacteria" id="BAF90226">
        <property type="protein sequence ID" value="BAF90226"/>
        <property type="gene ID" value="AZC_4228"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4228"/>
    <dbReference type="eggNOG" id="COG1946">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_032690_0_0_5"/>
    <dbReference type="OMA" id="SQVWFRT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047617">
        <property type="term" value="F:acyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042171">
        <property type="entry name" value="Acyl-CoA_hotdog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003703">
        <property type="entry name" value="Acyl_CoA_thio"/>
    </dbReference>
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        <property type="entry name" value="HotDog_dom_sf"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
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        <property type="entry name" value="tesB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="310" mass="34315" checksum="086E3783389E43E5" modified="2007-12-04" version="1">MTDQSTAWLVRHPASFRPSFANPMSDVETLRAILDLEPLEINLFRGRSGSPGGGRVFGGQVVAQALVAAQRTVDETRKPHSLHAYFLLGGDPTVPIIYEVDRIRDGKSFTTRRVVAIQHGRAIYSMAVSFQVPEEGIEHQSRMPDVPPPEASPSDEQWREKLVARFPAAAKRDWMALRPLEVKPVGLSPSFLAGKEQEARPGIWFRTRGALPDDVGIHQAVLAYASDLSLLQAALVPHGRSVFDADMQVASLDHALWFHRPFRADDWLLYIQDSPSAQGARGFCRGEIYSRDGKLVASAVQEGLMRVLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="80" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT90</accession>
    <name>A8HT90_AZOC5</name>
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        <submittedName>
            <fullName evidence="8">Peptide ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_0811</name>
    </gene>
    <organism evidence="8 9">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <sequence length="290" mass="30777" checksum="EC3FE3115E210100" modified="2007-12-04" version="1">MQIAGLTPASGTPSFSTLVPVSPDGSNARGDLLYIQQPLARLHVASKSAATALVSGVPAAIKTVVLDTAADVDGGNGAIYRRVDTAPTSGTYFRTADRFTLSGSTSSTNGGYWVLSDLASPLPIRNYIQDRNKQDLRDYNGIDFTGSNDCASILQTAANEAEDSNPIRYEVPGTITLVSPITLKDGTTLSGLVRPGVRTGADNGSWFYFAHSGKGFTGGYGGSNKVRSVTIRGIGTTRYQLVPGPGWAPQPHDFDFDFRVDDLTLEDVLILNATKGIRMSGWARLIAKNV</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTS5</accession>
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                <person name="Suzuki T."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="2 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <property type="protein sequence ID" value="BAF90416.1"/>
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        <property type="protein sequence ID" value="BAF90416"/>
        <property type="gene ID" value="AZC_4418"/>
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        <property type="entry name" value="Integrase_cat-core"/>
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        <property type="entry name" value="RNaseH-like_sf"/>
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        <property type="entry name" value="RNaseH_sf"/>
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        <property type="entry name" value="LZ_Tnp_IS481"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="rve"/>
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        <property type="entry name" value="INTEGRASE"/>
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    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="128"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90416.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="314" mass="34824" checksum="322087402D65BFD3" modified="2007-12-04" version="1">MNIHKHARMTFHGRVLLAQRITVEGWRTADAAGAAGISVRTAYKWLARFRAGGEAALHDASSAPGRKPRATSGETVAAIEALRRQRLSGPAIAHSLGLARSTVGAILRRIGLSRLAALDEKRPANRYQKAMPGELIHMDTKKLGRIDGIGHRITGDRTRQSNRRGTGWECLHVAIDDASRLAYTEVLPDEKKGTVCAFTARALGWFARHGVVTARLMTDNGSAYKSHDFRDLLRAAGVRHVRTRPYTPRTNGKAERFIQTSLREWAYAVPYTSSRQRTQAMPGWIDTYNLNRPHSAHNGLSPWTRLNNLLGNDI</sequence>
</entry>
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    <accession>A8HUD6</accession>
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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        <property type="evidence" value="ECO:0007669"/>
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        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
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        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
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        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="253" mass="25362" checksum="7E220B21A86EDF07" modified="2007-12-04" version="1">MDVKGHAAVVTGAASGLGAVTARALAAAGAKVALLDREVEGAARVAAEIGGQAFACDVVDAASAEAAVAAAAAAHGPARILVNCAGVAPAGRIVGRKGPQPLEDFRRVVEINLIGTFNLLRLVAAGAVGLEPLARGERGVLINTASIAAYDGQVGQPAYAASKAGVAGLTLPAAREFAGVGIRVVTIAPGIFATPMMLNMPQEVQDSIGATVPFPPGLGDPEDYARLVLHIIGNTMLNGEVIRLDGALRMAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
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    <sequence length="430" mass="44800" checksum="09DC7198AE2065D1" modified="2007-12-04" version="1">MTLSPSSPTTARNVGEGYAMKIKRFRASLMAIGLALALTGGAQAAPRGPSGDAFYVPPTPLPKGEKGSVIQARALSGTMALPSAAKNLLVLYQSEDPKGAPVAVSGTISIPKGKPPAGGWPVITWTHGTVGLAAVCGPSRDTAKGPEHEYIAAIRPLLDAFVAKGYAVVATDYQGLGVAGFHPFFQGVPNGKNALDLLRAARTLEPAIGTRYAVMGHSQGGQADLFTAAIGPDYAPEFQLVGNVAMAPGANMAGRFDAVRLSDKTELAVPYVLYALHSFSTTDSAIDLARILTPQALAHMADLQKGCMTRTLTQGYWSTAIAKDQFLPKQDVTALLKVAAQNEPGTLRISAPTLLMQGTADVTVRPQDTDAVARDLCVKGNTLTYKTFPKTDHDGVMKAGAADALAFLSDRFAGKPAASNCSDLPRAAAK</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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        <property type="entry name" value="HTH_LacI"/>
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        <property type="entry name" value="HTH_LacI"/>
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        <property type="entry name" value="LacI/GalR-like_sensor"/>
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        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
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        <location>
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        <location>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF90402.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="397" mass="42219" checksum="EE18BD83D2CCADF6" modified="2007-12-04" version="1">MPVFRPSWPGENAKVKTRKGPAPDASRPSAAGAGHTGSGAPARVTLNDIAAHAGVSRATVSLVLRKSPLVADDTRAKVDAAMVELGYIYNRRAANLRSGASRTIGLVLCEIITPNYAQFTSGIDEVLDGEGYAAFITNSEEDATRQRRLLVRMQEHGVDGIVLVPAEHTRPDALTEAHCTSVPCVVAQRRIEGFPTDYVGPDYAAGMEMVTEHLIALGHTHIGFIGGLRRISPLAERLTGFRRALRRHKLKSGPVVPCPVLDRADGYAAARSLLAAGDHPTALVCYNDVVAFGVMLALTEHGLTPGRDVAVVGCDDVAEAGLHRPALTTFTTDPRVVGREAARLLLRRIENPQLPPEQIIIPPRLVIRQSCGAAFGAPARTAGAGKPPARRATARPA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BA14k family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="gene ID" value="AZC_4446"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="BA14K"/>
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        <property type="entry name" value="BA14K"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
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    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002723997" description="Lectin-like protein BA14k" evidence="8">
        <location>
            <begin position="24"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010270"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="173" mass="17708" checksum="9AFB98E9B4185ED5" modified="2007-12-04" version="1">MRISSTSALSSLALALMAGLALAPPPAAAGALQLGTLPAPAAEAARAPVTESVQYRPGWGGPGWGGGWRGGPGWGGPGWGWRGGWGPPPPPAWGWRAGGWGPGPYWGGYYGYGPGWGFAPGFATGVIVGSAVAAPPPPPPPANWYAYCASKYRSFDPRTGTYMGYDGRRHPCT</sequence>
</entry>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="9">Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.</text>
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        <subcellularLocation>
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</entry>
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            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="CAZy" id="GT83">
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        <property type="gene ID" value="AZC_1580"/>
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    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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    <dbReference type="GO" id="GO:0005886">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="RgtA/B/C-like"/>
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        <property type="entry name" value="PMT_2"/>
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    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
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    <feature type="transmembrane region" description="Helical" evidence="8">
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        <source>
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            <dbReference type="Pfam" id="PF13231"/>
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            <dbReference type="EMBL" id="BAF87578.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
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            <dbReference type="Proteomes" id="UP000000270"/>
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    <sequence length="596" mass="64710" checksum="F5A505938B5E4ABA" modified="2007-12-04" version="1">MPARRFCYCPRRIRPGSASRMAITAPASTTRRPLALELAHRLSRGFDAAAGSHVRACALLLIVTLVAFLPGLGSISPIDRDEARFAQASKQMLESGNYVDIRFKEDVRYKKPVGIHWLQVASVSVGEALVGPSARTTIAFYRIPSLLGAIGAVLLTYWTALAFVGRRGALLAGLMMASCVLLGIEARLAKTDAVLLFTVLASMGVLARSWMAAPDVKRLSFGLSAIFWTGLAGGILIKGPMAPLFVGLPIVVLAIMERSGRIFTRLRPLPGILWCLLLVLPWFVAIYYVTNGQFYKLAVGVDMLGKVTEGQEGHWAPPGTYLLAIWGTFWPSIVLAVMALPFAWRMRRERAVRFLLAWIVPTWIVFEITATKLPHYVLPLYPALAILTALAFERGNLSAGRRLAPLVWLWPVMGTLLVGALVFGFVMLGQGLALLAWPFMALALVLLVFAARVLPEAGPQPAFLIAVAGALALYIGVFQGLMPQLRGVWISERLAAIARDSGCPADRIATVPYQEPSLAFLAGTNIRFTGPDGAADLMKEGGCALAFIGKPMLPFFEARSKAIGVEPKLLERVDGFAYNGGRMQEISVFRAPERTP</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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        <property type="gene ID" value="AZC_4516"/>
    </dbReference>
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    </dbReference>
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        <location>
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        <location>
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        </location>
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        <location>
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF01551"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF90514.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="668" mass="70497" checksum="96A815D3EE31EA91" modified="2007-12-04" version="1">MTAAVFLKADLSYEAPPLGLDGAEHGEAGSRPARARFNRRWLSATGLMGGVALALMCGALFASITRDSRHVVRPVLAGRRSGVEKPRGDRLHTQQARADASALKREVKVEQLTASGMHAFVHVATKLATVVAAAADQPPAPRPRPPLPAEDGELPDAGADVPPPMAANMSAHAVASARRAGLKAAHSRVAEAQAAAAAALEAMARHPNTAPPPPPTALGFAPPPPPPSHLPPEILTGASVPPPPTPAPPPQEGPPAPSLAMFEDDLTAIGEPVNVSVLAKHPHEPATVDRVLVAKPGDAPEDMLRAAGLDSEDAQVLATALRKAAMAGKPAFAGGEELVLSEPKGEESARPPRPIKASLARAGKPVARLVATDAGAYVPMPDAPPVTPTALADGEVDPSLIDGLSIRDGLYKLADAHVVDEGMVEAILRLAEHDVDLDAPLGAEDSIDLVYGPPDRNDNRPEAFQQDIAFVRLKADGKERRYYRFRTADDGATDYYDSDGHSVTKMLLRKPFAAGRLNDGFGWRIHPILHDRRFHNGVDYTGPAGSPIVAAGAGVVEKIDYEWGYGKYVRVRHDGGYETTYAHVEGFPSGLKVGQRVRQGQVIAYVGSTGLSTGPHLYYELRINGHYADPTRVKLAGGRILQGDLADAFRKERARMDALAAAVPTPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="40" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="9"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="305" mass="32547" checksum="6CA389E49D938913" modified="2007-12-04" version="1">MRPHFAEYLATFVDVVRAGSFSGAARRRAVTPSAIVRQIDALERDLGVSLFIRSTRALTLTDAGQRLHERAVRHLDDLADTHAEIAAFEGSVTGTLRIACFPTFGKRYVLPVVVGLQAKHPALLVELDLTERLADPVAERLDVVIRMGALTDSTLIATKLAPLARLLVASPAYLARAGTPTSAADLSSHRLIDKLHGADLLGWRDVLGCPAGFGGNGTVALRSDDFEAQRAAAEAGLGIAFLSSWVVGPDVKAGKLIRLLSGDEPWNQGPSGVYALRALPQPSAKVKAFIEGLRKTIGSPPVWEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8I1A6</accession>
    <name>A8I1A6_AZOC5</name>
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            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1352</name>
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    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1352"/>
    <dbReference type="EnsemblBacteria" id="BAF87350">
        <property type="protein sequence ID" value="BAF87350"/>
        <property type="gene ID" value="AZC_1352"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1352"/>
    <dbReference type="eggNOG" id="COG1344">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_011142_1_0_5"/>
    <dbReference type="OMA" id="ENWIAGE"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00207">
        <property type="entry name" value="FLAGELLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="6" id="KW-0282">Flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="4">
        <location>
            <begin position="18"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="5">
        <location>
            <begin position="280"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="366" mass="37241" checksum="A490C5F651AA3601" modified="2007-12-04" version="1">MSLHHVHSNDGTSVMTSIITNNAASVALATLRSINDSLNTTNDRVSTGKKINSAADGAAYWNISTTLTSDNGALGAVKDAINLDLASVKTTNTGVTQIMNSLNTIKQALVSAQSSTADRTSLQKNIANAVSDIKSAASSAVVNGANWLSVDSSATGFNANKSLLANFSRTSGVVSVGSTTLDTGAFAVYDAKTNGTATGTSSTIDKAVTAVATSATVSGGLTVAVGTNAGNLKGFMDTTYSISGSVGGTTVAAFTASIADIDISALTSSDVDLAKLSSYMKIVSATIDGLQNGSTALGTTQTRLTSQQSFAQSLIDINTSSIGSLVDANMEEESTKLKALQTQQQLAVQSLSIANNSTSNIMTLFR</sequence>
</entry>
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    <accession>A8I1X5</accession>
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        <alternativeName>
            <fullName evidence="7">Queuosine biosynthesis protein QueG</fullName>
        </alternativeName>
    </protein>
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        <name evidence="10" type="ordered locus">AZC_4676</name>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the QueG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4676"/>
    <dbReference type="EnsemblBacteria" id="BAF90674">
        <property type="protein sequence ID" value="BAF90674"/>
        <property type="gene ID" value="AZC_4676"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4676"/>
    <dbReference type="eggNOG" id="COG1600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_030790_0_0_5"/>
    <dbReference type="OMA" id="ICDTDLS"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00916">
        <property type="entry name" value="QueG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="243"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cob(II)alamin binding" evidence="7">
        <location>
            <begin position="308"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF90674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="448" mass="48154" checksum="28354FCAD99AEE0D" modified="2007-12-04" version="1">MRLSPPQPSPASGRGSEVTRVQRCHAQHGKSPLPLAGKGWEGAKRRLSSPRRGSPPMSAPARKTAPLSPSDLKDQLRALALEEGFDAFGIADPDAVGDAGTRLRHWVAEERYGDMGWMAETLDRRVHARAMWPEALRVVMLGMNYGPDEDPRTVLAERSLGAISVYARGEDYHDIIKPKLKRLARALLALAGTGDVKVFVDTAPLMEKPLAMAAGLGWQGKHTNLVSRARGSWLFLGAIATTLDLPVDAPMGDHCGQCRACLDACPTAAFPAPYQIDARRCVSYLTIEHKGPIPRDLRPLMGNRIYGCDDCLAACPWNKFAELGREAKLAARDENRAPDLADLATLDDAAFRARFPKSPIKRVGRGRFLRNVLTAIGNSGDPALVASARAHLGDPDALVRGAAVWALSRLLPAAEFATLAAVQAGAEADAEVAAEWTAALEADAPPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="89" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2E1</accession>
    <name>A8I2E1_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease R</fullName>
            <shortName evidence="4">RNase R</shortName>
            <ecNumber evidence="4">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnr</name>
        <name evidence="7" type="ordered locus">AZC_1859</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1859"/>
    <dbReference type="EnsemblBacteria" id="BAF87857">
        <property type="protein sequence ID" value="BAF87857"/>
        <property type="gene ID" value="AZC_1859"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1859"/>
    <dbReference type="eggNOG" id="COG0557">
        <property type="taxonomic scope" value="Bacteria"/>
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    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
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        </location>
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        <location>
            <begin position="1"/>
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    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="778"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001849"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50126"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="BAF87857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="814" mass="87976" checksum="6C2C0556B9E12B71" modified="2007-12-04" version="1">MSGRPAQLDFCPCHCGPRDTPLPKRPSTPKRPAPSRKTRAVRQPDAPAFKATGVLPGKEEVLAFIASQGGKVSKRDIARAFGLGSGQKIELKALLRDLKDEGAVEGGRRRMHVPGSLPSVVLVDVTGRDGDGELLAVPTEWDSEEHGDAPVILLHVPDKLRGPAPGLSDRIVVRVEPNDPAPGIGYTGRVIKVLEKARKQQLGVFRKAPPGSSGGGRIIPIDKKNLGRELQVPPGAENGAEDGDLVSVEMMHQRVFGQPTARVKERLGSLATEKAISLVAIHAHGIPNAFPAKVIAEAEAARPATAKGREDWRKLPLVTIDPPDAKDHDDAVHAVPDDDPDNAGGFIVTVAIADVAAYVRPGSALDREALLRGNSVYFPDRVVPMLPERISNDLCSLRPQEDRAALAVRMVIGKDGRKRSHSFHRILMRSAAKLAYEQAQAAIDGVSDDTTAPLLESVLRPLYAAYACVKQARDARQPLELDLPERKILLKEDGTVDRVIVPPRLDAHRLIEEFMILANVAAAETLEQKKVPLIFRVHDGPTLAKLSALREFLATLDISLPKTDQVRPSHFNRILGMVDGGDSAPLVNQVILRSQSQAEYSSENYGHFGLNLRRYAHFTSPIRRYADLVVHRGLLRTLGADADALPETATVETLAEISADISATERRAMAAERETVDRLIAHHLAEQIGAVFQGRITGATRAGLFVALDETGADGFVPAASLGQDYYRFDETRQALVGDRTGEMHRIGDRVEVKLVEAAPVAGALRFELLSEGSYLGRGKSAKGRGAERPASKAAKARAGFAKRTAGRAPRKGR</sequence>
</entry>
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    <accession>A8I347</accession>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170507.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1980"/>
    <dbReference type="EnsemblBacteria" id="BAF87978">
        <property type="protein sequence ID" value="BAF87978"/>
        <property type="gene ID" value="AZC_1980"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1980"/>
    <dbReference type="eggNOG" id="COG1028">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_010194_1_3_5"/>
    <dbReference type="OMA" id="GELMWRL"/>
    <dbReference type="OrthoDB" id="1601931at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="235" mass="23928" checksum="BB7ED23E91F7D75E" modified="2007-12-04" version="1">MNAVSSEGGGRVPHALVTGVSSGIGAEIASQLLALGWRVTGFSRGQPGQEHPALTHVPVDISKRGALAEALLDLAPLDALIHAAGILRVGTLGALDPENGKAMWRLHVDAAEQMIEATVAAMPEGARIVLIGSRTAAGSAGRAQYAATKAALVGMARSFAIELAPRRITVNVIAPGATDTPMLRDPSRASVTPKMPPMGRLVQPKEVASLAAFLLSDGAASITGQQIVVCGGASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3E8</accession>
    <name>A8I3E8_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">ABC transporter substrate binding protein</fullName>
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    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_2015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170542.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2015"/>
    <dbReference type="EnsemblBacteria" id="BAF88013">
        <property type="protein sequence ID" value="BAF88013"/>
        <property type="gene ID" value="AZC_2015"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2015"/>
    <dbReference type="eggNOG" id="COG0747">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_017028_7_1_5"/>
    <dbReference type="OMA" id="MFHTWHA"/>
    <dbReference type="OrthoDB" id="162819at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0574">Periplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002720848" evidence="3">
        <location>
            <begin position="29"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="76"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF88013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="533" mass="58603" checksum="DC65D39C4C4B8A54" modified="2007-12-04" version="1">MDRRTFLKGAAGAGSLAMSGGFAMPALAQGAAKTLRFVPQANLANFDPIWGTQYVVRNASVLVWDTLYGLDANQKPQRQMVESEEVSADGLTWTFKLRPGLKFHDGEKVLAKDVVASLTRWSARDPMGIMLKNIQKELVAVDDNTFRWVLSKPYPKMLLALGKTNAPIAFIMPERIAQTDPFKQITEYVGSGPTKFLKNEWVPGAKAVFERFADYVPRNEPASWISGGKKMLVDRIEWVVMPDPATAAAALQNGEVDWWEQPLSDLVPLLKKNKNLNVDIGDPLGNVGSFRMNHIQPPFDNPKVRRAVLMALSQEDYMRAVVGDDEALWKTLPGFFTPGTPLYTEEGGEILKGKRDLDAAKKLLAESGYKGEPVVCVVAQDQPITKAQGDVTVDLLKKLGMNVDFVATDWGTVGSRRALKTPPTQGGWSMFHTWHAGSDCVNPAAYPAIRANGDKAWFGWPESPAVEAEVVSWFDAKDLNEEKAAIGRLNKAALENVTYAPTGFFLTYTAWNKKVTGVTKGPIPTFWGVAKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="94" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4D7</accession>
    <name>A8I4D7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ordered locus">AZC_1719</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170247.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1719"/>
    <dbReference type="EnsemblBacteria" id="BAF87717">
        <property type="protein sequence ID" value="BAF87717"/>
        <property type="gene ID" value="AZC_1719"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1719"/>
    <dbReference type="eggNOG" id="COG0449">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_012520_5_2_5"/>
    <dbReference type="OMA" id="ASEYRYA"/>
    <dbReference type="OrthoDB" id="43416at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="283"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="455"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF87717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="607" mass="65401" checksum="EB85A4794DA3DBB4" modified="2007-12-04" version="1">MCGIVGILGQGPVAEDVIDALKRLEYRGYDSAGIATLEHGHLAICRAEGKLRNLDQKLARHPLAGHSAIGHTRWATHGKPSERNAHPHSGKKVAVVHNGIIENFRELKDELIAGGAHFLSETDTEVVALLVDRELRAGRSPVEAVGKVLPRLRGAFALAFLFDGEDDLLIAARKGSPLAIGYGKGTMYLGSDAIALGSFTDEIVYLEEGDWAVITRAGAEIRDLTGAVVKRPMVKVPAGAMLVDKGNHRHFMAKEIYEQPEVIPHTFGHYIDPTKETVVLPELPLDLGSVTHISITACGTALYAGAVAEYWFERFARVPVSIDIASEFRYRETPLQPGGITIVISQSGETADTLASLRYAKELGQKVVAVVNVPTSTIAREADVVLPTLAGVEIGVASTKAFTCQLATLACLAVATGRAKGVLTSDDEHRLVRAMMEVPRLMTEALKLSPEIELLSRTLAKAQDVLYLGRGTNYPLALEGALKLKEISYIHAEGYAAGELKHGPIALIDEKMPVVVIAPYDRVFEKTVSNMEEVAARGGRIILVTDQKGADLANVTAMQKLILPEMPATIAPLIYSIPVQLIAYHTAVLMGTDVDQPRNLAKSVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="85" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5L0</accession>
    <name>A8I5L0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="8">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="8">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fabH</name>
        <name evidence="11" type="ordered locus">AZC_2294</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2294"/>
    <dbReference type="EnsemblBacteria" id="BAF88292">
        <property type="protein sequence ID" value="BAF88292"/>
        <property type="gene ID" value="AZC_2294"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2294"/>
    <dbReference type="eggNOG" id="COG0332">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_039592_3_1_5"/>
    <dbReference type="OMA" id="WGSEGDK"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="10">
        <location>
            <begin position="109"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="9">
        <location>
            <begin position="237"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="8">
        <location>
            <begin position="252"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF88292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="324" mass="34093" checksum="0CB6D4608A434C4B" modified="2007-12-04" version="1">MIGIHSVVRGVGSYLPQKVLTNADLAEMVDTSDEWIVQRTGIKERHVAAEGEFTSALGLKAAQAALADAGLVADDIDLIILATSTPDQTFPATAVTIQSELGITRGAAFDLQAVCSGFVFAIATADAHLRTGAFKRALVIGAETFSRILDWNDRGTCVLFGDGAGAIVLEGVPADEAKGRGVLTSHLRSDGRHRSKLFVDGGPSSTGTVGHLRMEGREVFKHAVGMITDVIVDAFAATGESAETIDWFVPHQANRRIIDASAQKLGIAPEKVVTTVQSHGNTSAASIPLALDVARKDGRIKPGDLVLLEAMGGGFTWGSALLRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A8I653</accession>
    <name>A8I653_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2364</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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            <begin position="10"/>
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    <sequence length="399" mass="41422" checksum="1CD9DBBF262C103E" modified="2007-12-04" version="1">MHDDRKPGQRDVWITGIGLVTSLGEGLDAHWTALAEGATPVVDTESFKPYIVHPLVKLNYDQQIPKKGDQRQMEAWQRIGTYAAGLALDSAGIAKNPEILGRTDMVVAAGGGERDFQVDAAILNDLLASNDWGRSLNERLLSDLRPTLSLAQLSNLLAGNISIVHGVTGSSRTFMGEESAGVDAARVAYSRIAAGQSEIGLVGGAYNAEREDMLLLYALNDLCMTGDYRPVLGAETAPGIPSGSMGAFLVLESPEHATARGAKPIAKLSGVWSERARRTEAGTVAAKVGELIADAGKTPGTVVYSAATGAPGATEAEGEALKAAGLPVRVATNRIGHGFEAQFSAVIALAALSLSRGAAIAPLAASPLETAQDGALERVIVTSVGHWRGEGAALVEKAG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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        <text evidence="1">Belongs to the bacterial solute-binding protein 7 family.</text>
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    </evidence>
    <sequence length="333" mass="36470" checksum="3EEA1D0BCB5BE997" modified="2007-12-04" version="1">MSLFSRGLAAACLAASALILSPLAADPAAAQTKLKWAHVYEPSEPFHTASVWAAGEIAKRTNGRYQIDVYPSSQLGKESDLNQGLTLGTVDMIISGSSFAGKAYPPIGVTYYPYTFRDADHLLAYAKSDVFKDLAKGYEDKTGNHIVAVTYYGVRQATSNKLFKTCAEMKGLKIRVPDAPAYLAMPKACGANITPIAFAEVYLALQNGTVDAQENPLTTIEAKKFFEVQKNIILTGHIVDHLNTVLSPSLWAKLSPEDRKIFTDVAQEAAAKASKEVAAREKELIAVFKEKGLTIVEVDTNDFRDTVMKNIPFESFGYRKADWERIQALKSSM</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the alanine racemase family.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="4 6"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2065"/>
    <dbReference type="EnsemblBacteria" id="BAF88063">
        <property type="protein sequence ID" value="BAF88063"/>
        <property type="gene ID" value="AZC_2065"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2065"/>
    <dbReference type="eggNOG" id="COG0787">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028393_1_1_5"/>
    <dbReference type="OMA" id="HMTHFSD"/>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="9">
        <location>
            <begin position="267"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="6">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="6">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="336"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6 7">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF88063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="393" mass="40871" checksum="D4256F833DAD6BA8" modified="2007-12-04" version="1">MRGNADDPAVNFALQNGADDAMNDYRAKTMLADGGCGVLTIDLGALARNYRKLKETAAPAAVAAVVKADAYGLGAGLVSERLYAEGCRHFFVAHFVEAVRLRPTLPVEATLLVLNGLMPGEEEHAADLGVTPVINCLEQAAAWATEAKVRGTRLKAAIQIDTGMSRLGLSEADVASLRADSLFAEAVEPILLMSHLACADTPAAPASAGQLAVMQRVAAHFPGLPVSLANSGGVFLGGAFHFALARPGIAVYGGAPVSDVANPMEPVVRIDIPVIQARTVPAGTAVGYGGTFVTTGETRLATLSGGYADGIPRHLSSSGALYYQGVRLPIAGRVSMDSLTVDASALPEGGLRLGTMVEFVGPSQSLEQVAADAGTISYEILTRLGRRYRRVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7F3</accession>
    <name>A8I7F3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Isocitrate lyase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170642.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2115"/>
    <dbReference type="EnsemblBacteria" id="BAF88113">
        <property type="protein sequence ID" value="BAF88113"/>
        <property type="gene ID" value="AZC_2115"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2115"/>
    <dbReference type="eggNOG" id="COG2513">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_027389_3_2_5"/>
    <dbReference type="OMA" id="FIAWPDM"/>
    <dbReference type="OrthoDB" id="1485205at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016833">
        <property type="term" value="F:oxo-acid-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="301" mass="32051" checksum="6E480CBC8D4E73E9" modified="2007-12-04" version="1">MSLKARLAQERVLPAPGIYDALTASLAAAAGFEALYLSGAAIAYTRLGRPDIGLVSMTEVAEVIALVRDRVPTPVIVDADNGYGNALNVQRTVRTFERAGASALQLEDQTMPKRCGHLQDKSLISTAEMIGKIKAAVDARTSEETLIIARTDAVAVEGFEPAIERARLYAEAGADVLFVEAPRSQDQLAAVTRALGNGLPLLVNMVEGGDTPLATTEELGELGFKIVIFPGGIVRALARTAQAYYRSLFTNGSNEPFREHMFDFSALNGLIGTADLLAQGREYDVFGAALADAPLTRKAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7G5</accession>
    <name>A8I7G5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2119</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2119"/>
    <dbReference type="EnsemblBacteria" id="BAF88117">
        <property type="protein sequence ID" value="BAF88117"/>
        <property type="gene ID" value="AZC_2119"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2119"/>
    <dbReference type="eggNOG" id="COG0654">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_033626_0_0_5"/>
    <dbReference type="OMA" id="CRFIAFM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="27"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="423" mass="46526" checksum="C4F23B2876F0BE05" modified="2007-12-04" version="1">MRAPQTEAILRRMTDPLPCPTVFTARCAIVGAGPAGLMLGLLLARAGVEVIVLEKHKDFLRDFRGDTIHPSTLEVMHEIGLLEGLLKLPHTQAPKLHAEIGGTDVTLADFSRLPTRCRFIAFMPQWDFLDYVARQAARYPSFQLLMSTAVEDLIEENGRVVGLRATCDGAPMEIRAGLVVAADGRHSRVRAKAGLAVEAFGSPRDVLWMKLSRQSDDPPYTMGHAGPRQGFVMIDRGDYWQCGYVLKKGSFDEVKRAGLDAFRATVAAVSPLPASRMDEVRDWTDVSLLQVRIDRLTQWWKPGLLCIGDAAHAMSPIGGVGVNLAIQDAVAAANILTAPLLKGAVDEAALAAVQKRRTFPTKATQKLQLMMQKDRRKRETDARRSSGPPAFVRTIARWPLLAHLAGRLVGLGFRPEHVRDRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8I962</accession>
    <name>A8I962_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_2748</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171272.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2748"/>
    <dbReference type="EnsemblBacteria" id="BAF88746">
        <property type="protein sequence ID" value="BAF88746"/>
        <property type="gene ID" value="AZC_2748"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2748"/>
    <dbReference type="eggNOG" id="COG3490">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_047398_0_0_5"/>
    <dbReference type="OMA" id="AGLWDNH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008311">
        <property type="entry name" value="UCP028101"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07433">
        <property type="entry name" value="DUF1513"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="369" mass="38237" checksum="FA5D541588B77EE7" modified="2007-12-04" version="1">MGFSRRSLLGLASAVIAWPRRSYADVHALDEGWLTTAGLDKGFGALAMGTDMTAAPKATTPARLHGIEASPNSPLAVAVGRRPGHVALVFDRARGGLVSQFAPGEGRVFSGHGRFSPDGALFLTNEIERGIEDGPRRTMGRGMVAVRSVAGKFEITAEWSTNGDGPHDLMRVGETLVVANGGIEPHTPEARDAEVSGSTISLLDPASGSIRGEGALSQDLASLSLRHLARDGQGGVVVAAQDLLADGVARPLLFDIAKDGKLTAYEAPENELRALRGYVGSVAIDASGAFVACASPRGGRVSVWQRNGRYVGAVPLVDGCGLAATPEPGRFIATSGYGEVIVIAAEADGLGVVARRTGGPRYDNHMVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9S5</accession>
    <name>A8I9S5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-related sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2826</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <begin position="527"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="580"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="DctM" evidence="5">
        <location>
            <begin position="324"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="646" mass="68623" checksum="B6DBC345F1BD2D62" modified="2007-12-04" version="1">MIQNRVFKTGLLCALAVALSTLGPEMAFAADGGLRAFVTHNMAPIMFGALVIFLLLGYPVAFALAANGLVFGVIGIELGLFRPDFLQALPERVYGTMNNEVLLAVPFFTFMGLILERSGMAEDLLDTIGQVFGSIRGGLAYAVIFVGALLAATTGVVAASVISMGLISLPIMLRYGYDRRVASGVIAASGTLAQIIPPSLVLIVMADQLNRSVGDMYEGAFVPGLLLAGLYAFYIFLVSAIFPSVAPGLPLEAQTLRDKNQKRGPSRLLGAIFAAGFAVLIATGSLPGLTAGSLPGAANLAVWGVGAFVLFYFIMSGTARLLTPSLFIALSIAIGISIAVMERSGMRVGSDYVVLAMSMTVGLAFVVAVINRVFRLGLLSKLAEQVIFVMVPPLALIFLVLGTIFIGVATPTEGGAMGSVGALLLAAGRGRLKFDLMRQATYSTAKLSAFVLFILLGSRVFSLTFYGVDGHRWVEELLVSLPGGQTGFLIVVNILVFLLAFFLDYFELAFIIIPLLGPAADKLGIDLIWFGVMLAVNMQTSFMHPPFGFALFFLRSVAPKVPYLDRVTGKRMEPVTTGQIYWGAVPFVGIQLIMVALVVLFPGMVTHYKSSSVQLDQGAVQKQFDNLTPDLDSAPPPPALDFGAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAY9</accession>
    <name>A8IAY9_AZOC5</name>
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        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2583</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2583"/>
    <dbReference type="EnsemblBacteria" id="BAF88581">
        <property type="protein sequence ID" value="BAF88581"/>
        <property type="gene ID" value="AZC_2583"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2583"/>
    <dbReference type="eggNOG" id="COG0631">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_034545_0_3_5"/>
    <dbReference type="OMA" id="NNEDFHR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="243" mass="26425" checksum="1AF08358C88CE217" modified="2007-12-04" version="1">MQAQPGARPYDTVRVVRAGVFEISLASRQGPGRENNEDAVFSNPETGVHLVADGVGGLPYGEVASWEIVQACTAIHAADLSFMDRLEWLEDRLLAANHTLYQAGMTAPQAFTMASTVVAAQVEDDRAGLFWAGDSRAYLRHHGRLLQLTTDHVELRDRRRLVTRLVGATPDPELDFRIVQIDPGARLLLCTDGIFDAVPPEVIGATLDLERRDLATALLEAADCYSGRDDATAIVLRHVGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="61" xmlns="http://uniprot.org/uniprot">
    <accession>A8IB00</accession>
    <name>A8IB00_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_2588</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2588"/>
    <dbReference type="EnsemblBacteria" id="BAF88586">
        <property type="protein sequence ID" value="BAF88586"/>
        <property type="gene ID" value="AZC_2588"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2588"/>
    <dbReference type="eggNOG" id="COG2226">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2835">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043922_0_0_5"/>
    <dbReference type="OMA" id="YLWSHFA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
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    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
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    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="2">
        <location>
            <begin position="287"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="487" mass="51714" checksum="642CB41CEE5C7FAC" modified="2007-12-04" version="1">MSGAPRHAPRSPPRRQGDASRPALPRADASGRACADAGAASAHATADHEGLHDRAHRQHACGAGHRHHHPLHAGRLRPRRARHDRHGLRHRADRQPAGGAGGRHDGPHKLRRAHSCTHGHGDGTGLHHRHHRRVTMRLLHHETLKPVCPACRQTGAEHPLALEAGAVIVEGDVRTGILRCSGPACGKAYPILSGTPILVPDVSSWLAANLHLVLQGEVESEAVESLLGDALGPDAAFNVVRQQQSTYGHDHYGDVFSGGVAAPTGSVRQALAQALAHLPAKAGPSIDLGCAAGRTTFDLAAATGRPALGIDLNWHLLRLGRTVLDDGHVLYPLRRSGNRFERRSARVNLPGAALCDFWIADALALPFAGGTFGYVSAFNVLDCVSRPTALIAEARRVLKAEGGLALSTPFDWATHATPPNEWLDGPAAARAVLQGHFPAPAGAPASGMAQELRLPWHVRLHDNAVVHYEAYVFLASKKDVSSGHQAA</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-08-03" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC06</accession>
    <name>YACG_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA gyrase inhibitor YacG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">yacG</name>
        <name type="ordered locus">AZC_3144</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Interacts with GyrB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA gyrase inhibitor YacG family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171668.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IC06"/>
    <dbReference type="SMR" id="A8IC06"/>
    <dbReference type="STRING" id="438753.AZC_3144"/>
    <dbReference type="EnsemblBacteria" id="BAF89142">
        <property type="protein sequence ID" value="BAF89142"/>
        <property type="gene ID" value="AZC_3144"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3144"/>
    <dbReference type="eggNOG" id="COG3024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_178280_2_2_5"/>
    <dbReference type="OMA" id="CSNRCRE"/>
    <dbReference type="OrthoDB" id="2071775at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008657">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00649">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005584">
        <property type="entry name" value="DNA_gyrase_inhibitor_YacG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36150">
        <property type="entry name" value="PTHR36150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03884">
        <property type="entry name" value="YacG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0479">Metal-binding</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0862">Zinc</keyword>
    <feature type="chain" id="PRO_1000072686" description="DNA gyrase inhibitor YacG">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00649"/>
        </source>
    </evidence>
    <sequence length="68" mass="7650" checksum="15545A58927A62BC" modified="2007-12-04" version="1">MSDETAKPFEPKPCPICGKPSIERYKPFCSKRCADVDLNRWLTGAYAIPVVEEEDEDGEPLSPPLRPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A8IC38</accession>
    <name>A8IC38_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3156</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171680.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF89154">
        <property type="protein sequence ID" value="BAF89154"/>
        <property type="gene ID" value="AZC_3156"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3156"/>
    <dbReference type="HOGENOM" id="CLU_2420670_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="91" mass="9887" checksum="0437C8E41C936ED6" modified="2007-12-04" version="1">MTIKTIGNVVHLPAPPEAPQAASAPIPTSPSDQIYAQAVDALSDYRRLAAIPELSAGQKREIDLARDRVVEYLCLARAIARIEQQDLPAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8ICF3</accession>
    <name>A8ICF3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3201</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="996" mass="102192" checksum="D389E14F3D1F5D15" modified="2007-12-04" version="1">MANGAARTRQAPDREMLRAGGECDARSRFSRRNGKQAGFRWGRCLRAFVVGNFFMPSHRPSPARRGFLLASTAVCLAAPAQAQTANPWATPEYYASQALRQINAAAAYAQGYTGAGVTVGVMDAAVDGRHPEFSGRMVPGWDFLNNRPTGQFDNMPDDSHGTHVAGIIAAARNGEVMQGVAFNARIMSVAYNWRVTSEDEIFASSWNYLAASGVPIVNNSVGMNDCDRAPAGPCNVTSYTRAKVEAELPQTLAAMRATARAGVLMVFATGNETQPHPDVLAGMPYLVPELKDTWLAVNLVSSVDLAVSWGNRCGVAKDWCLVAPGYNILSTVPLGEGFGLYRGYDTMSGTSMAAPSVSGAAALVKEAFPWFTAHDIQQAILTTATDLGEPGVDNVYGWGMLNVGKAVLGYAMFTGTTTLDTQGMTSTFSQDISGAGTLIKTGAGELILTGANTYSGGSWVDGGTLSINGSVASNVYVGQEGLLRGTGQIFAQLAVAGRLAPGNSPGTLTVAGPVLMSPTATFQVDIDGTGTGTGAGNYSRLVTTGPTGTVEVAGTLAPQLRGITGSATNSYTPTLGTTLRVIEASAGVSGSFSGLAQPIGLAAGTRFDALYGANDLSLIVTPAAYGTLSVLGLATSRNGTAVGGALDSVRPAAGVALTGSLGAFYQSLYTLQAAALPATLAQLSGEAHASAEAMAFDDARHIRSAVLERLDGSGVAAAPLAPGLTASVWLSGYGGWAHASGGDAAALYWDASGFVAGIDAPVTEMVRFGLAAGFGQSSGTVGDLTSDIDNTHIDLAAYAVAEGAGWRAKAGVAYGWNDLSMTRAIGFGSVAEGLATKQDGRTVQAFGEISRDLVLGHAQVSPYANLAYVNQRLDAFAETGGVAALSGSAQTLSTTLATLGARLAIGLPMGNATVTPNVNLGWQHAFGDVATEAVMTLAGSSPFRVYGVPLARDALVLGGGLTYGFGNSVAASVAYDGLIGSDVTESSIKADLRFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDF5</accession>
    <name>A8IDF5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MoCF_biosynth domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171455.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2931"/>
    <dbReference type="EnsemblBacteria" id="BAF88929">
        <property type="protein sequence ID" value="BAF88929"/>
        <property type="gene ID" value="AZC_2931"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2931"/>
    <dbReference type="eggNOG" id="COG0303">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG2068">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_505971_0_0_5"/>
    <dbReference type="OMA" id="VVIMPGC"/>
    <dbReference type="OrthoDB" id="472474at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012184">
        <property type="entry name" value="Bifunc_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036626">
        <property type="entry name" value="MPTBd_MobAlike"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="1">
        <location>
            <begin position="167"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="539" mass="55470" checksum="14E4928519BBA868" modified="2007-12-04" version="1">MRFGPVPLAEAEGAIAAHSIRCGDRVIRKGTRLAADEIAALSGAGHASVVVARLEADDVPEDAAAHELARAIAGPGLRVEAPFTGRSNLFAQAAGVVAIDRAGVDAFNGRDEALTLATIPDLRPVQAGDMVATVKIIPFAVPAPLVREAARTAPLLTLHPFVRRKVALVSTLLPGLPPKVVEKTRRVTAGRLAPAGAALSHDVQIPHDTAALAQAIRTAASEGADLVLIFGASAITDRRDVIPAALEAAGGHVERLGMPVDPGNLTLIGRLGDLPVIGAPGCARSAKENGFDWLLMRLLAGLDVTAAEVAGLGVGGLLGEIVTRPQLREEPPAPHAPEIATLILAAGRGTRMGGPNKLLADVGGTAVVRRVAEAALVAGPRPVVVVTGHEHERVEQALAGLAVQFIHNPDHLTGMASSLRRGIAALPPGVEGAVVALGDMPLVSAELFGRLGAAFAPELGRLIVVPMAGEQRGNPVLLSRRFFPDLMALEGDIGARRIIAAHPEAVVEVEAPSTAAFLDVDTPQALDEARTLLGSAQGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDL7</accession>
    <name>A8IDL7_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome c oxidase subunit 2</fullName>
            <ecNumber evidence="15">7.1.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ordered locus">AZC_2960</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="20" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="19 20" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 15">Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>4 Fe(II)-[cytochrome c] + 8 H(+)(in) + O2 = 4 Fe(III)-[cytochrome c] + 4 H(+)(out) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11436"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="7.1.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="15">Binds a copper A center.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.9" evidence="15"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2960"/>
    <dbReference type="EnsemblBacteria" id="BAF88958">
        <property type="protein sequence ID" value="BAF88958"/>
        <property type="gene ID" value="AZC_2960"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2960"/>
    <dbReference type="eggNOG" id="COG1622">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_036876_2_0_5"/>
    <dbReference type="OMA" id="HAFMPIA"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd13912">
        <property type="entry name" value="CcO_II_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034210">
        <property type="entry name" value="CcO_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014222">
        <property type="entry name" value="Cyt_c_oxidase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00116">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02866">
        <property type="entry name" value="CoxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0186">Copper</keyword>
    <keyword evidence="8 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="18">
        <location>
            <begin position="61"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="17">
        <location>
            <begin position="157"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="BAF88958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="313" mass="34513" checksum="B60ACC758DFCBD99" modified="2007-12-04" version="1">MHGNHGLCARAFGRQGRHVRRLCRPRRGPKMMSLRRAGALAVAASCWMGLSLAAAHAGLGQPSDWQMNLQQAATPVMESIRSFNTFLLVIISSIVLFVLVLLAICIVRFNEKANPVPSKTTHNTLLEVAWTVVPVMILVAIAIPSFRLLHLELHTPEPDMTVKVTGHQWYWSYEYPDNGGFGFDSLMVAEKDLKPGQPRLLAVDNEVVVPVNKVVRIHVTSADVIHSFAVPSFGVKIDAIPGRLNESWFKATKEGVYYGQCSELCGRDHAFMPLAVRVVSQQDFDAWLAQAKQKFADTQAPVPTQVADAAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDU0</accession>
    <name>A8IDU0_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative D-aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2992</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S58 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171516.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2992"/>
    <dbReference type="EnsemblBacteria" id="BAF88990">
        <property type="protein sequence ID" value="BAF88990"/>
        <property type="gene ID" value="AZC_2992"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2992"/>
    <dbReference type="eggNOG" id="COG3191">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024709_0_0_5"/>
    <dbReference type="OMA" id="YWGHGSG"/>
    <dbReference type="OrthoDB" id="2000083at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005321">
        <property type="entry name" value="Peptidase_S58_DmpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36512">
        <property type="entry name" value="PTHR36512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03576">
        <property type="entry name" value="Peptidase_S58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="348" mass="36368" checksum="4549E7FC6D7A9F68" modified="2007-12-04" version="1">MKRARDFGLVCGSLPPGPLNAITDVPGVRVGHRTLVDGDVRTGFTALVPHEGDLFREKLPAAVEVINGFGKSCGLIQVEELGQLETPILLGNTLSVGTGFEALVRRALAANPDIGRETGTVNPVVMECNDGWLSDIRALALTVDDAHAALDAAVSGMVPEGAVGAGAGMSAFGFKGGIATASRLLTLDGRDYTLGVLVLANFGRAGDLVLPDGRRPEVPKLRKSDFASVDAPERGSVIIVLATDIPLESRQLKRIARRCGAGLAKLGAFWGNGSGDIALAFSTAARIAHHETADLLPRMVLNENRIDLPFRAAADATQEAVLNALLAAPRTRGRDGHMRPSLADVLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="60" xmlns="http://uniprot.org/uniprot">
    <accession>A8IDV4</accession>
    <name>A8IDV4_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2999</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <comment type="similarity">
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                <person name="Lee KB."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172142.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3619"/>
    <dbReference type="EnsemblBacteria" id="BAF89617">
        <property type="protein sequence ID" value="BAF89617"/>
        <property type="gene ID" value="AZC_3619"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3619"/>
    <dbReference type="eggNOG" id="COG0162">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_024003_0_3_5"/>
    <dbReference type="OMA" id="YMMAKDS"/>
    <dbReference type="OrthoDB" id="402899at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
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    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
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    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
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    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
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    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="9">
        <location>
            <begin position="378"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="44"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="256"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF89617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="437" mass="48071" checksum="8882BDB2F2420971" modified="2007-12-04" version="1">MTTLRSDFLRTLQERGYIHQCSDLERLDAKASEGPITAYIGFDATASSLHAGHLLSIMMLRTLQRTGHRPIALMGGGTTKIGDPSGKDEARKMLTDAQINENIASIRKVFARFLDFEGSPKGYARFARAVDGKWNEEPRLLPAIMENNANWLDELKYIPLLREVGPHFTINRMLTFDSVKLRLEREQPLTFLEFNYMILQAYDFVELNKRHGCTLQMGGSDQWGNIVNGMELGRRMHGADLFALTTPLLTTSSGAKMGKTAGGAVWLDAALLSPYEYWQYWRNTGDADVERFLKLFTELPLDEIARLAALGGQEINHAKDVLATEATALLHGRAAAEEAKATARATFEEGALSTNLPTIEIPAADLKAGLAANSAFVTAGLVPSTSEARRQIKSGGLKVNDATVTDEKLVLGERDLTAEGVIKLSMGKKKHVLVRPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A8IFR6</accession>
    <name>A8IFR6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor RpoD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Sigma-70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoD</name>
        <name evidence="10" type="ordered locus">AZC_3643</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3643"/>
    <dbReference type="EnsemblBacteria" id="BAF89641">
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    <dbReference type="eggNOG" id="COG0568">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="480"/>
            <end position="493"/>
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            <end position="675"/>
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    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
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            <end position="669"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="7">
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            <end position="153"/>
        </location>
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            <end position="266"/>
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            <end position="526"/>
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    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
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            <begin position="480"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
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    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
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            <dbReference type="ARBA" id="ARBA00023163"/>
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    </evidence>
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            <dbReference type="HAMAP-Rule" id="MF_00963"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="PROSITE" id="PS00716"/>
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        <source>
            <dbReference type="EMBL" id="BAF89641.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="690" mass="78072" checksum="290C6F4438163839" modified="2007-12-04" version="1">MNWDERWRAGGTPLSPPRGDVQEMSMAKQATETTEAPEKEVDAPDGPLLDLSDAAVRKMIKSAKRRGYVTYEQLNEVMPSEEVTSEQIEDTLAMLNDMGINVIEAEEAEAEEASEEGETADEPEEVDSGELAEQSPRAVVRSETKSEPGERTDDPVRMYLREMGSVELLSREGEIAIAKRIEAGREAMIAGLCESPLTFQAIIIWRDELTEGRVLLRDIIDLEATYAGPEGKAGPVIEGETALAPEAGEDGLLNDSAAPGDDEDDMENSLSLAAMETEIKPKVLETFERIADNYKKLRRLQDQNVESKLKNETLSPAQERKAKKLKEDLVLDMKSLSLNQARIDSLVEQLYEINKRLVSLEGRLLRLAESYGVARDDFLRQYQGYELDPKWLLRVSKLGSKGWKEFVAHEKDGIHTLRGDIHALATETALEIAEFRKIVQMVQKGEKEARQAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKIVRTSRQMLHEIGREPTPEELAEKLGMPLEKVRKVLKIAKEPISLETPIGDEEDSHLGDFIEDKNAVLPIDAAIQSNLRETTTRVLASLTPREERVLRMRFGIGMNTDHTLEEVGQQFSVTRERIRQIEAKALRKLKHPSRSRKLRSFLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGF2</accession>
    <name>A8IGF2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF559 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_0081</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0081"/>
    <dbReference type="EnsemblBacteria" id="BAF86079">
        <property type="protein sequence ID" value="BAF86079"/>
        <property type="gene ID" value="AZC_0081"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0081"/>
    <dbReference type="eggNOG" id="COG2852">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_955292_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="2">
        <location>
            <begin position="102"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="291" mass="31031" checksum="CD8A7F40CF481EE8" modified="2007-12-04" version="1">MMDAARDMAGARTAIGRLRPAVLPPSLPSPARGEGSVAHAKPSCFEPPRSSPRNAPPPPLRGRAGEGGNAAPTGSTLSATAPEPPMPNEERPTAHRPISPRLKGNAKALRREMTDAELTLWQHLRAHRLEGAPFRRQAPMGRYVADFVCHPARLIVELDGGQHGGPEDQARDNWFAAQGYAVVRYWNNDVLGNLGGVLEDLSARVIERVKVESVLPPSPTLPRKGGGGDDLPLPTPKRLRAPLPPAHREPSPLEGEGREGGKTAGPENARSETSPTPIRTRTPASTGGHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="90" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGH8</accession>
    <name>A8IGH8_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator receiver</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
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    <reference evidence="5 6" key="1">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Ussery D.W."/>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="446"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="BAF86123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="665" mass="72004" checksum="A9ABEDEF02D83A12" modified="2007-12-04" version="1">MDALAVNAKQARMPTWAGQVPCRYRHRCGARCGGKVPAGLDPVHLTHLECVMTFRRRDFLISLALAVLCAVVAGWAGYKMVCAAGINEQHALAERRMDIANETLEREIEKYGLLPRTAAVSPNVIDFLSRPATAEGVAEINRQLRTLNDSAGTLQTYLVDPSGRIVASSNWSEKDSFIGRDISYRPYFQNAQPGRTTGYYAVGTTGDAPGYFLASAVEDGGRRLGVVAVKLGLDQLERLWLGQPEPALMVDDNGIVVVSSVPDWKFGALRPLPAATLAHLEASQQYNHREIRTLDWKVLTTFRNGSFLVRAGTPAGTATYLAAGRPVPDLHMHMIVLSEPREVYRVAWGWAIACAALAALACALLHVLNMRRLSIRERLAMREALQASHDRLEILVEARSAELRRANEGLRREVSERIQAVKQLQSFQEELIRTENLAVIGQLSAGIAHEINQPLAALSTLSANAVRFLERNDLATVRLNLGRISDLVARMGALTGQLRSFARRSTGEIGATAVGLRVDGAVALLAHRLTKDGVVVELLPPGGVLTVLCDPVRLEQVLVNLISNAVDASSDLRVPHIQVSWGAEGESGIIRVRDNGIGLTDAVKAHLFEPFFTTKKTSGLGLGLAISADIIRGFGGALTADNNPDGGATFTITLPLAEQKETCDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="91" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH08</accession>
    <name>A8IH08_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="7">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">OMP decarboxylase</fullName>
            <shortName evidence="7">OMPDCase</shortName>
            <shortName evidence="7">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrF</name>
        <name evidence="10" type="ordered locus">AZC_0159</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7 8">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 7 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the OMP decarboxylase family. Type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="7"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0159"/>
    <dbReference type="EnsemblBacteria" id="BAF86157">
        <property type="protein sequence ID" value="BAF86157"/>
        <property type="gene ID" value="AZC_0159"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0159"/>
    <dbReference type="eggNOG" id="COG0284">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_067069_1_0_5"/>
    <dbReference type="OMA" id="NFKIFLD"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01200_B">
        <property type="entry name" value="OMPdecase_type1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32119:SF2">
        <property type="entry name" value="PTHR32119:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 7 8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="9">
        <location>
            <begin position="11"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="66"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="BAF86157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="236" mass="23968" checksum="4AEA523FCBAD711F" modified="2007-12-04" version="1">MTDVSPDIRDRLIVALDYPNVGAAEALVWQLGDAVSFYKVGLELTVGGGLDLAADLIDAGKKVFLDLKMHDIGNTVEKATAAAAERGVSLLTVHAYPQTMAAAARGAKGSALQVLGVTVLTSYDEADLAAAGYAQGVTETVRRRAIQAQEAGIAGVICAPTDAAMVRAATSPDFQIVTPGVRPAGSAAGDQKRFATPADAMAAGANRIVVGRPITGAADPSAAARSILEELAKAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8IH26</accession>
    <name>A8IH26_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ordered locus">AZC_0165</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    </dbReference>
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    <evidence type="ECO:0000259" key="1">
        <source>
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    </evidence>
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        <source>
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    <sequence length="273" mass="30338" checksum="908C79B6054E5A75" modified="2007-12-04" version="1">MGAGFLISIGEPLFHSDPEGLIGKQALRGRRAFQVDVAMPPSLTLYELTGADDDLRFSPHCWKIRMALLHKGLEADRRPWRFTEKDAIAFSGGATVPVLVDGDKTVTDSWRIALHLEEHHADRPSLFGSETGRSYARFVNSYADTVLVAPLRHLLTLDILARVHEKDRDYFRASREKRFGQPLETHAGDPAVHIPAFRAALTPVRTVVAEQPFLSGAAPAYADYCAFGALMWARCVSPLRLLEKDDPVYGWRERMLDAFGGHARAAACTEQDA</sequence>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="STRING" id="438753.AZC_3276"/>
    <dbReference type="EnsemblBacteria" id="BAF89274">
        <property type="protein sequence ID" value="BAF89274"/>
        <property type="gene ID" value="AZC_3276"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3276"/>
    <dbReference type="eggNOG" id="COG3474">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_060944_2_0_5"/>
    <dbReference type="OMA" id="AQCHTIN"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="PTHR11961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
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        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002724498" evidence="6">
        <location>
            <begin position="26"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="26"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF89274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="128" mass="13339" checksum="DE540FEB5A2BA72F" modified="2007-12-04" version="1">MAFRQTPLIMCLALTLLGTGGAAHAQDAAAGERLFRARCASCHAVESGQNRIGPSLSGVIGRKAGSLEGARYSQGMRALDVTWDAAQLDTYLANPRAMVPGTTMTVSVTSAADRAAITGYLQTLSQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IHP5</accession>
    <name>A8IHP5_AZOC5</name>
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        <submittedName>
            <fullName evidence="3">IMP dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ordered locus">AZC_3304</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171827.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3304"/>
    <dbReference type="EnsemblBacteria" id="BAF89302">
        <property type="protein sequence ID" value="BAF89302"/>
        <property type="gene ID" value="AZC_3304"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3304"/>
    <dbReference type="eggNOG" id="COG1305">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG4196">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_008973_4_0_5"/>
    <dbReference type="OMA" id="KWYPGES"/>
    <dbReference type="OrthoDB" id="670657at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013589">
        <property type="entry name" value="Bac_transglu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018667">
        <property type="entry name" value="DUF2126"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08379">
        <property type="entry name" value="Bact_transglu_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09899">
        <property type="entry name" value="DUF2126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="172"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="556"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="560"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1112" mass="123904" checksum="6F549F23063E4A7B" modified="2007-12-04" version="1">MSILASLHHVTSYKYDRPVSLGPQIIRLRPAPHTRTTVPAYALKIEPKTHFLNWQQDPFGNWQARLVFPEKATEFRIEVDLLADLAVVNPFDFFIEEYAEHIPFTYAPEVKSELTPYLELEDGGPLLDAFVASIPLEKRRAVDFLVELNQRIQKDVGYIIRLEPGVQTPDETLASGKGSCRDSGWLLVQVLRRLGLAARFVSGYLIQLKPDVKSLDGPSGTDVDFTDLHAWAEVYLPGAGWIGLDATSGLLCGEGHIPLAATPHYRSAAPITGLVEKAEVTFEFDMKVTRVAEAPRVTLPFSDESWAALNALGAKVDADLEANDVRLTMGGEPTFVSIDDYQSAEWNTAAMGPMKRVRADDLIRRLRHRFASGGLLHYAQGKWYPGETLPRWSFGLFWRKDGKPIWHDDALIADENTNYGVGPEQAGRFSQALAERLGLSADHAQPAYEDIAHYILKEANLPENLEPGDPRIEDPFARNTMARAFAQGLGTPVGYVLPIQQVWGPTGSGWLSEQWKFRRGHLFLVPGDSPIGFRLPLSSLAYIPPTLYPHTVAADPLEARDPLPDPDEMAQGYRRDGKDGPIPAAARARRVVESYLASTPAAGPFYVRTALAVEPRDGRLCVFMPPVEALEAYLDLVTAIEATAAELNMPVHLEGYPPPFDYRLNVIQVAPDPGVIEVNIHPSATWQGCVDVTRGVYEEARLARLGTEKFMIDGRHSGTGGGNHVVVGGRTPADSPFLRRPDLLKSLILYWQRHPSLSYLFSGLFIGPTSQHPRIDEARHDSLYELEIALSRFPMPGTDLPPPPWLVDRLLRNILMDVTGNTHRTEISIDKLYSPDGPTGRLGLVEFRCFEMPPDWRMSLAQQLLLRALIASFWRKPLDGGCVRWGTSLNDRFMLPHYCWSDFLDVLDDLKGAGYDFDPEWFRAQFEFRFPAFGKVQRAGVDIEVRQALEPWHVLGEEGAIGGTVRYVDSSVERVQVKVDGFVPGRFVLTCNGRPVPLTPTGRNGTFVGGVRYKAWQPPEGLHPTIPVHTPLQFDLVDTWNGRSRGGCVYHVAHPAGRNYETFPVNSYEAEARRLARFENHGHTPGTMAHVPLETAPNEFPTTLDLRRPASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIG9</accession>
    <name>A8IIG9_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_3405</name>
    </gene>
    <organism evidence="2 3">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168751.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0220"/>
    <dbReference type="EnsemblBacteria" id="BAF86218">
        <property type="protein sequence ID" value="BAF86218"/>
        <property type="gene ID" value="AZC_0220"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0220"/>
    <dbReference type="eggNOG" id="COG0457">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019981_3_0_5"/>
    <dbReference type="OMA" id="DELRFRY"/>
    <dbReference type="OrthoDB" id="1382732at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="603" mass="64449" checksum="22D3B9246A8C5783" modified="2007-12-04" version="1">MDAILDTPPPGEEDGEAARVRAALARVLASDEFSSSPRLADFLRFVVEAKLGGRAEEIKGYTIAVEALGRPASFDPQSDPIVRVEATRLRRALERHYSGAGVDDEMEIVIPKGSYVPHFRPRGAAAEVLPEETQRPTGEDAIPVVAPQVAGSGLRRWGVPAVVLVFLVMLGTLGVRAVSGAWPFASLFAQAEGPRDLADRLGMPIIDVRPFETVGSRAPTQAETHAIEARLRDAFARFDFVDVMEPGQEASVRECRDPPPRSVFALSGLAEGREDGTFSLLVRLSDRCEGTIVWSADFEGLRRGSDMPATEQRVVRDIAVALMQSYGVLPTRARSQARADASPSGFGCIAQVYSLSRGSEAETPQGVRECLAREARQHTGFGLAHAVTAQIALDEIRRNPAAPADPDMLAQMLRNAELAADLAPTSAYASKVLAKVDYMRGERDAALAAAERALALNPLDYDVAADVGMVRIGLGQPEQGEALLNFARAHGALRTPMQDAFIAISAFLREDAHAAAGVLAPLQLHPSPQTRIGLALALKALGRTEQEHEVVMALVRETPDGAAGVRRVVHTMLPYADTAEPVLSELEQAGLGPRAVSAGSTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="92" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ06</accession>
    <name>A8IJ06_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Homoserine O-acetyltransferase</fullName>
            <shortName evidence="2">HAT</shortName>
            <ecNumber evidence="2">2.3.1.31</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Homoserine transacetylase</fullName>
            <shortName evidence="2">HTA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">metXA</name>
        <name evidence="6" type="ordered locus">AZC_0229</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>acetyl-CoA + L-homoserine = CoA + O-acetyl-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13701"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57716"/>
            <dbReference type="EC" id="2.3.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. MetX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.31" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0229"/>
    <dbReference type="EnsemblBacteria" id="BAF86227">
        <property type="protein sequence ID" value="BAF86227"/>
        <property type="gene ID" value="AZC_0229"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0229"/>
    <dbReference type="eggNOG" id="COG2021">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028760_1_2_5"/>
    <dbReference type="OMA" id="TRFCVVS"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00074"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004414">
        <property type="term" value="F:homoserine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00296">
        <property type="entry name" value="MetX_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="PTHR32268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01392">
        <property type="entry name" value="homoserO_Ac_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="5">
        <location>
            <begin position="66"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2 3">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <feature type="active site" evidence="2 3">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="403" mass="44076" checksum="6DFFDE5FEEC5EF3D" modified="2007-12-04" version="1">MGETVKIETGRQTAEDVKARREADEPHSPLVRFGADKPLRLDAGVELRGLQVAYQTYGEPNADRSNAILVCHALTGDQHVANVNPVTGKPGWWETMVGPGKPIDTERFFVICANVLGGCMGTTGPSSTNPATGRAYGLEMPVVTIRDMVNAQAMLLDHLGIERLFCVAGGSMGGMQVLQWAASYPERVFCALPIATAARHSAQNIAFGEVGRQAVMADPDWRGGDYLNQGVAPHRGLSVARMAAHITYMSDQALHRKFGRRLQNRVLPTFGFDADFQVESYLRHQGESFVQRFDANSYLYVTRAMDYFDLAADYDGVLANAFRSSKTRFCVVSFTSDWLFTTQDSRAIVHALNASGASVSYAEIESDKGHDAFLLEEPELFDISRGFLDSAARAAGLPPARTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ59</accession>
    <name>A8IJ59_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Methyl-accepting chemotaxis receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_0254</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <text evidence="3">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </dbReference>
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        <property type="entry name" value="DNA_lig_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="3">
        <location>
            <begin position="308"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="552" mass="61816" checksum="C0DB76F6D3211380" modified="2007-12-04" version="1">MNRFAELLDRLSYEPRRNAKIRLMSEYFRSTPDPERGVALAALTGKLSFTNAKPGLIRALIAERTDPVLFELSYDYVGDLSETVALMWPAPKGLPEMGGNHAPFLSEIVEGLETLPKRDLPRQLALWLDGLDETGRWALLKLITGALRVGASARLAKTAVAALGDLPPDEVELVWPGLSMPYRELFAWAEGKGERPQTTDPVPFRPVMLAHAIEETDFSALDPASFAAEWKWDGIRVQAVCARSSDGTRAARLYSRTGEDISGAFPDLVEALDFDGALDGELLIVREKRVETFNVLQQRLNRKAVTTKMLAEFPAHIRAYDLLAVAGEDLRPLPFRDRRARLEALIARLETQGHTRLDLSPLVPFADWEGLAAARRDPASAGAGLDAEAVEGVMLKGWDTAYLPGRPKGPWWKWKRDPHTVDAVLMYAQRGHGKRSSFYSDYTFGVWTQGEEGDVLVPVGKAYFGFTDQELIEIDKFVRRATINRFGPVREVLHEPDEGLVLEVAFEGLARSTRHRSGVAMRFPRIARLRWDKPPREADRLETLEALLRQEE</sequence>
</entry>
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            <fullName evidence="3">Putative amino acid ABC transporter periplasmic solute-binding protein</fullName>
        </submittedName>
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        <name evidence="3" type="ordered locus">AZC_3870</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3870"/>
    <dbReference type="EnsemblBacteria" id="BAF89868">
        <property type="protein sequence ID" value="BAF89868"/>
        <property type="gene ID" value="AZC_3870"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3870"/>
    <dbReference type="eggNOG" id="COG0834">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_019602_18_4_5"/>
    <dbReference type="OMA" id="ITYFMDG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="2">
        <location>
            <begin position="74"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF89868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="312" mass="34692" checksum="5CCE7A4F217954BB" modified="2007-12-04" version="1">MNEHRLSFSNAAFLAKIPPRLEFLNNPTRGLDMKIVLKAVRVLLATGFVSWAVPAAQAATPMPSPPELITSQGVLRAGVRCDQPPYGFQDGSGAFAGVETDMARQIADWIFGSKDKVEFTCVTAENRIPQLTGKRVDLLIATLGVTPERQRVIDFSIPYRWGASGLLVRADSPFQKVADLDHHTVVMPKGTVQAKWFEDMMPGVKTLRLNTAADSLQALKQGRADGYAHDAATLVVAAAQDKSLRLLNDPYQTSEVSIGLRKDEPTWKTYLDAAVERMHAEKLFRVWVEKYVSAEARPYYLEFFETPRPDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKD9</accession>
    <name>A8IKD9_AZOC5</name>
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        <submittedName>
            <fullName evidence="7">Putative ABC transporter permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF89893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="gene ID" value="AZC_3895"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3895"/>
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    <dbReference type="HOGENOM" id="CLU_046113_2_1_5"/>
    <dbReference type="OMA" id="ARYWELF"/>
    <dbReference type="OrthoDB" id="916788at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
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    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
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            <dbReference type="EMBL" id="BAF89893.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="257" mass="27607" checksum="BB7573D378EDBA13" modified="2007-12-04" version="1">MSYALRRRLSSTAVIIGFFVLWEAACVIFHIKEIVLPRPSQVLATLWLQAPAIWPHTVQTLYTTLIGFALGIVSGVLLGVVIGSSRLAYDTGYPLLIGFSSIPKVAVVPIFVLWFGAGTVPAVLTAMIMSLFPIVVNVATGLATTEPELEDVMKALRATKLDILFNVGLPRAMPYFFASLKVSVTLAFVGTVIAETVASNRGIGNLMMIASSSFDVPLVFAGLLVLALLGVGLYAIFSLIEGRVIGWARRKDDYAMG</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3915"/>
    <dbReference type="EnsemblBacteria" id="BAF89913">
        <property type="protein sequence ID" value="BAF89913"/>
        <property type="gene ID" value="AZC_3915"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3915"/>
    <dbReference type="eggNOG" id="COG1816">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_522460_0_0_5"/>
    <dbReference type="OMA" id="IAFERDM"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="A_deaminase" evidence="5">
        <location>
            <begin position="308"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF89913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="565" mass="61220" checksum="B460931B59A415CC" modified="2007-12-04" version="1">MRRPPDEISGRRMQHRKLQRSRDSRGARGRPCRRDPSGALIVRRRIAIAAFVLIAAALVVRLAFVTRDLPATLTAGQFETLRAELPRMRAFLARMPKGGDLHTHLSGAVYAERFIGVAVRDGLCLRRADWTLLPRPAGAPADHPCGTDPALVPLAEAVAGGRGQTTYDLLVNALSTRWFVPTLAVPSGHDQFFGTFGKFNAATGGPEWDSTARATAEMVVDQLRQYEAEQVQYAEFMVTLFEGEDRRRLAQALLASPAAAGGIDGQSDPVPLLEAVKGAGLADLVSARAAQLKDLVARIEALRGCAGDRGKPGCTVAYRFIAQVNRNAPPAEVFVQTAHAAALVRAAPGIVAGLNYVGPEDYRISLRDYRMHMRWIGALAGHDVPVALHAGELWLGLVPPPDLTFHIREAVEVAGARRIGHGTAIAFERDMDGLLAQMRRKDVAVEIALTSSDVILGVRGPEHPIRTYLSAGVPVVLSTDDAGVSRIDLTNEYFRAARDQGLGYGQLKAMARAAITHAFLPLDERQWQLGRLDSAFLAFERKVASDLPLPTKARLVARAMLPAGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="43" xmlns="http://uniprot.org/uniprot">
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
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        <name evidence="1" type="ordered locus">AZC_3917</name>
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        <lineage>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3917"/>
    <dbReference type="EnsemblBacteria" id="BAF89915">
        <property type="protein sequence ID" value="BAF89915"/>
        <property type="gene ID" value="AZC_3917"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3917"/>
    <dbReference type="eggNOG" id="ENOG502ZBVC">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_902059_0_0_5"/>
    <dbReference type="OMA" id="WTAYLLV"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF89915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="329" mass="37456" checksum="B3467B436E4EF37D" modified="2007-12-04" version="1">MDPKRELGRCRRRQPAKLRRETVLTSPAVPPAAKGKRPATRLYAILARDARTGVVFRRGPSRQVQLIRWDLRDDTFEHGQWFKGRIYERRCDLSPSGKLLLYFAATHRAPFYTWTALSKPPFFTALALWPKGDAWGGGGMLDDEETVLLNYLPDGDAPRFPLAEGFRLKPGMQVKPCGQWSGRGEDEPLNTLLLERAGWRLVERGEGEARGLKAPEIYKFSKPQVREKDGPGGRRLQMLLRVVGRAGKPFYGLDYRVVDRDGTVLVDLPETDWADWDGGDLVFARAGCLHRLRKSRFRDYADKGEDAFLRLHDFSDARFAPLEAPYAAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKR2</accession>
    <name>A8IKR2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">map</name>
        <name evidence="5" type="ordered locus">AZC_3940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172460.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3940"/>
    <dbReference type="MEROPS" id="M24.036"/>
    <dbReference type="EnsemblBacteria" id="BAF89938">
        <property type="protein sequence ID" value="BAF89938"/>
        <property type="gene ID" value="AZC_3940"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3940"/>
    <dbReference type="eggNOG" id="COG0024">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015857_0_2_5"/>
    <dbReference type="OMA" id="SAPEFCY"/>
    <dbReference type="OrthoDB" id="1285136at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="11"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF89938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="251" mass="26905" checksum="51443626637A7072" modified="2007-12-04" version="1">MTLSNDDELKAMQEIGRICAETLEAMSKAIEPGITTRELDGIGRAFLEAAGAQSAPETVYDFPGATCISINEEVAHGIPGDRVIRPGDLVNIDVSAHKNGYFADTGASFAVPPVTRAVEKLCRDGRRAMWAGLRQVAPGRLLAGIGQAVGAFAKKNGYTLVRNLASHGVGLSLHEEPTEIATWPDASDRRIITEGLVFTVEPFLSLGATLAENVEDDPWTLYSEPRALTVQYEHTVVATRNGPLVLTMPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="95" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKV2</accession>
    <name>A8IKV2_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ordered locus">AZC_3954</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="18" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <strain evidence="18">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <dbReference type="PROSITE" id="PS50885"/>
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    </evidence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0471"/>
    <dbReference type="EnsemblBacteria" id="BAF86469">
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    </dbReference>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86469.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="82" mass="9299" checksum="77CADF6C09704A41" modified="2007-12-04" version="1">MLRGPRARAAQEGRMIAIAVLLPWLALMLRGRIFQGILCLVLQITLIGWLPAAIWAVVVVNNDNEERRHRELMASLNGQRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="71" xmlns="http://uniprot.org/uniprot">
    <accession>A8IM43</accession>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Sato S."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="function">
        <text evidence="3">Removes the phosphate from trehalose 6-phosphate to produce free trehalose.</text>
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    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>alpha,alpha-trehalose 6-phosphate + H2O = alpha,alpha-trehalose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23420"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
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    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the trehalose phosphatase family.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.12" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
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    <dbReference type="HOGENOM" id="CLU_037265_2_0_5"/>
    <dbReference type="OMA" id="YGAERWD"/>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044651">
        <property type="entry name" value="OTSB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43768">
        <property type="entry name" value="PTHR43768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="261" mass="27215" checksum="AB8B956AFEAD80E9" modified="2007-12-04" version="1">MHVTSVPKEEGRPSRPDAVRLFDPRTCAFFLDVDGTLIDIAIHPDAVTVPSGLLTTLGTLKTAADGALALVSGRTVAGLDALFSPLKLAAAGVHGGEIRLTPEAPVAQQSATLPAETGTRISRLARDLDGVLMEDKGSSIAVHYRLAPQIGPDLQIALEQIVTDYPGLSLLPGRLVFEVKRAGCDKGVAVRQFMAAPGFAGRTPVFIGDDVTDEAAFAAVSQMGGIAVSVGRNLPVADLVLPEAQDVRALLATLVAQQPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8IML5</accession>
    <name>A8IML5_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Methylmalonate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_0575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169106.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0575"/>
    <dbReference type="EnsemblBacteria" id="BAF86573">
        <property type="protein sequence ID" value="BAF86573"/>
        <property type="gene ID" value="AZC_0575"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0575"/>
    <dbReference type="eggNOG" id="COG1012">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_005391_1_10_5"/>
    <dbReference type="OMA" id="NWTLRQP"/>
    <dbReference type="OrthoDB" id="490746at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004491">
        <property type="term" value="F:methylmalonate-semialdehyde dehydrogenase (acylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07085">
        <property type="entry name" value="ALDH_F6_MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010061">
        <property type="entry name" value="MeMal-semiAld_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43866">
        <property type="entry name" value="PTHR43866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01722">
        <property type="entry name" value="MMSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="16"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="498" mass="53353" checksum="5F3E5F21E9B1F3F1" modified="2007-12-04" version="1">MREMGHFIGGKHVPGTSGRHADVWQPMTGEVVGRVALASAAEMRAAVENAKAAQPAWAATNPQRRARVLMKFLELVQRDYDALADLLAREHGKTVPDAKGDIQRGLEVIEFAVGIPHLLKGEFTDGAGPGIDVYSMRQPLGVVAGITPFNFPAMIPMWKFGPAIACGNAFILKPSERDPGVPLKLAELMLEAGLPPGILNVVNGDKEAVDAILDDPDIQAVGFVGSSSIAQYIYARGAATGKRIQGFGGAKNHMIIMPDADMDQAVDALIGAGYGSAGERCMAISVAVPVGEAAAEKLIEKLVPRVESLKIGPSTDVTADFGPLVTREALERVKSYVDIGVNEGAKLLVDGRGFKLQGYENGFYLGGCLFDHVTPDMRIYKEEIFGPVLSVVRAKDYKEALRLPTEHEYGNGVAIFTRDGDAARDFASKVNVGMVGINVPIPVPIAYHTFGGWKRSGFGDLNQHGPDGVRFYTKTKTVTSRWPSGVKDGAEFVIPTMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="48" xmlns="http://uniprot.org/uniprot">
    <accession>A8IN40</accession>
    <name>A8IN40_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Liu C.T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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        <location>
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            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF86610.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="355" mass="36718" checksum="C91033170279AACE" modified="2007-12-04" version="1">MNGPFSLPRRAPRKVTQPKVTLAHGGGGTAMRDLIEDVFLETFSGAGHAAPEDQARFDLSALAAQGDRLAFTTDAFVVDPLFFPGGDIGKLAVCGTINDLAVGGARPVALSCAVIIEEGLPLETLRAVVASMARTAAEAGVVIVTGDTKVVARGACDKLFLTTTGIGVVRTGLDVGIAKGRPGDVVLVNGLLGDHGAAILNARGDLALETPIESDCAPLHDLVATLIAAAPGIRMMRDATRGGVAAVLNELAEASGVGVRIRETDVPLRPEVNGFCEILGLDPLYLANEGKLVAVVPPEEAEAALAAVRAHLLGREAAIIGRLAAERPGRVVMETRFGGERIVDMLVGDQLPRIC</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169150.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="SMR" id="A8IPG5"/>
    <dbReference type="STRING" id="438753.AZC_0619"/>
    <dbReference type="EnsemblBacteria" id="BAF86617">
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        <property type="gene ID" value="AZC_0619"/>
    </dbReference>
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        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="TEIGAMR"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="project" value="InterPro"/>
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    </dbReference>
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        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="123"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="123"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF86617.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
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        </source>
    </evidence>
    <sequence length="222" mass="25232" checksum="FA0C5AAD85FBB795" modified="2007-12-04" version="1">MYVVVDQRATVTDGYVSSFSREGFSSLGLGCNEFKEWLNTASDQDIGAVQGFLLGEFDNRPAFPEMIRTHSRAPIIALEDVRSLQQTLELFTAGIDDVVRKPVHVREIVARSDAVWRRVNSAAGPATNGRLRVFFDGRDPEVDGVPLPLPRRERHILEYLVKNSRRRVTKTQIFNTIYGIFNDDVDESVIEGHMSKLRKKLRMKLGEDVIDAKRYIGYQFIG</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012169216.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0685"/>
    <dbReference type="EnsemblBacteria" id="BAF86683">
        <property type="protein sequence ID" value="BAF86683"/>
        <property type="gene ID" value="AZC_0685"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0685"/>
    <dbReference type="eggNOG" id="COG0600">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046113_1_1_5"/>
    <dbReference type="OMA" id="CSIWPMI"/>
    <dbReference type="OrthoDB" id="1531811at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005889">
        <property type="entry name" value="NtrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01183">
        <property type="entry name" value="ntrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="108"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF86683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="302" mass="32430" checksum="55B2D66CE1A13E05" modified="2007-12-04" version="1">MSVTALKEAEPQRRPEAATPASVAQVVRLKRSRPPVSARLMAAARWFAVSVLPPLIVTALLLLLWELLCRGAGATLPPPSRIWADSKDLIVDPFFVAGPQDIGLGLRVLVSLQRVAVGFGLAAVVGVLTGALIGQSVWAMRGLDPIFQMLRTVPPLAWLPLALAAFRDSNPSAIFVIFITSIWPIIINTAVGIRNIPQDYRNVAQVLRLNPLEFFWKIMLPSAAPYIFTGLRIGVGLSWLAIVAAEMLTGGVGIGFFIWDAWNSSRLPDIIVALVYIGVVGFVLDRLVAGVAGIVTRGTAAS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="1994-02-01" modified="2022-05-25" version="58" xmlns="http://uniprot.org/uniprot">
    <accession>P33988</accession>
    <accession>A8IKL4</accession>
    <name>Y3924_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName>Uncharacterized protein AZC_3924</fullName>
        </recommendedName>
        <alternativeName>
            <fullName>ORF3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_3924</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1993" name="Mol. Plant Microbe Interact." volume="6" first="238" last="252">
            <title>Azorhizobium caulinodans nitrogen fixation (nif/fix) gene regulation: mutagenesis of the nifA -24/-12 promoter element, characterization of a ntrA(rpoN) gene, and derivation of a model.</title>
            <authorList>
                <person name="Stigter J."/>
                <person name="Schneider M."/>
                <person name="de Bruijn F.J."/>
            </authorList>
            <dbReference type="PubMed" id="8471796"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-68</scope>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="X69959">
        <property type="protein sequence ID" value="CAA49583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S33581">
        <property type="entry name" value="S33581"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="P33988"/>
    <dbReference type="STRING" id="438753.AZC_3924"/>
    <dbReference type="PRIDE" id="P33988"/>
    <dbReference type="EnsemblBacteria" id="BAF89922">
        <property type="protein sequence ID" value="BAF89922"/>
        <property type="gene ID" value="AZC_3924"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3924"/>
    <dbReference type="HOGENOM" id="CLU_2520497_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword id="KW-1185">Reference proteome</keyword>
    <feature type="chain" id="PRO_0000066466" description="Uncharacterized protein AZC_3924">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <sequence length="84" mass="9162" checksum="C1BFB95213A44C7A" modified="2008-02-26" version="2">MTDHECEIRSVDGSWEAVGVEEALGLPSSLLKRCPECHGRVRVHRASVNGMRAHFEHMEAHRGCSLSRGVQFSGVSSPHPAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="93" xmlns="http://uniprot.org/uniprot">
    <accession>A8HQN0</accession>
    <name>A8HQN0_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">Cysteine desulfurase</fullName>
            <ecNumber evidence="5 9">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">sufS</name>
        <name evidence="11" type="ordered locus">AZC_1047</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11 12" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="function">
        <text evidence="3">Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="5 9"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1047"/>
    <dbReference type="EnsemblBacteria" id="BAF87045">
        <property type="protein sequence ID" value="BAF87045"/>
        <property type="gene ID" value="AZC_1047"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1047"/>
    <dbReference type="eggNOG" id="COG0520">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_003433_2_5_5"/>
    <dbReference type="OMA" id="HKLCGPT"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF87115.1"/>
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    </dbReference>
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    <dbReference type="InterPro" id="IPR021508">
        <property type="entry name" value="Gp17-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11367">
        <property type="entry name" value="DUF3168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="137" mass="14277" checksum="9002CF0D3F208D6C" modified="2007-12-04" version="1">MSAPASAALALRKAIHQRLAADTALGALVAGAIHDVPPAGVPFPYVTLGEAVVSDWSTATEAGSEQALTLHVFSRQGGRAEAMALCAAVQEALHEAPLALDGHRLANLRATTAEVRRDGDGRTFHGFVRFRAVTEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRI8</accession>
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        <submittedName>
            <fullName evidence="7">Magnesium/cobalt transport protein</fullName>
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        <name evidence="7" type="ordered locus">AZC_1195</name>
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    <organism evidence="7 8">
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
                <person name="Lee KB."/>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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            <topology evidence="1">Multi-pass membrane protein</topology>
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    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF87193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="326" mass="36122" checksum="081ADF94F3A7DB06" modified="2007-12-04" version="1">MLIAYVPRAGALVSEVVAADANIPAGAVWLDLIAPEAFEDRTIERALGIEIPTREEMREIEASSRLYAERGARYMTLSVLCGAQTDTPEVTPVTFILTDAVLVTVRYSEPKAFPLLADRLRRACPDPLSAETLLAELLDTIIDRVADVLEMCGDGIDRLSRRTFEPQAKGSDANQIYRAILTQLGRKERLTSYARESLSSLTRLLAFLGADIVEGHTLSPKGRDAVKSMMRDVTGLSDYAVFLVTKLQFLLDATIGMVSLEQNNIIKIFAVLSVVLMPPTLIASIYGMNFQHMPELAETYGYPLALCAMVVSGILPYLFFKWRRWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="68" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRS6</accession>
    <name>A8HRS6_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPK2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4088</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:19575"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172608.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4088"/>
    <dbReference type="EnsemblBacteria" id="BAF90086">
        <property type="protein sequence ID" value="BAF90086"/>
        <property type="gene ID" value="AZC_4088"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4088"/>
    <dbReference type="eggNOG" id="COG2326">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_048699_1_0_5"/>
    <dbReference type="OMA" id="RTHYENV"/>
    <dbReference type="OrthoDB" id="953793at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022300">
        <property type="entry name" value="PPK2-rel_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03709">
        <property type="entry name" value="PPK2_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="5">
        <location>
            <begin position="31"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="281" mass="32371" checksum="3EB8C05DB6F25DAA" modified="2007-12-04" version="1">MDYRTAFLAKPGAPFRLADCDAGFHNAFSSRSEAQPEIDAQLKRMGNLQEKLYAERRHSLLIVLQGIDAAGKDGVCWHVLKGMGPQGCHVHAFKVPSDEEKAHDFLWRIHPHTPALGSVAVFNRSHYEAVLVERVHDLVPEQVWKHRYETINDFERGLELSGTTILKFFLFISKDEQLKRFGDRLDDPDRHWKISESDYTERARWDDYMAAYDDMIGRCSTEHAPWYVIPSNHKWFRDLAISQIIANTLQDMDLRPPEPNVDIAAIRKLYAAEVAKAKKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8HRX5</accession>
    <name>A8HRX5_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_4109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4109"/>
    <dbReference type="EnsemblBacteria" id="BAF90107">
        <property type="protein sequence ID" value="BAF90107"/>
        <property type="gene ID" value="AZC_4109"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4109"/>
    <dbReference type="eggNOG" id="COG1595">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_985710_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="125"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="223"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="44"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF90107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="282" mass="31030" checksum="82AA6C9066B3DEC4" modified="2007-12-04" version="1">MRMTGVRAAHGQSRRLAYSSAADRPRRQACLRAFMGCVGQRRGWNVDPDVGAPEPSARRRSGRNGRHRSSARIVPPERRIMSEPLSARDDGVAPNASPTTDERAAHNAMILAIAERQDRAAFAALFKHFAPRLKTFLMRSGLSATAAEEIAQETMLSVWRKAGYFDPAKAGAATWIFTIARNLKIDALRRERPVAQLPTEAEDTPDEAPNGEALVLAQEREDKVRAALSRLSADQANIVRLSFFQDKPHAQIAKELGIPLGTAKSRVRLALARLRALLEDIG</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HSH8</accession>
    <name>Y4184_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0391 membrane protein AZC_4184</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name type="ordered locus">AZC_4184</name>
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    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0391 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172704.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8HSH8"/>
    <dbReference type="STRING" id="438753.AZC_4184"/>
    <dbReference type="EnsemblBacteria" id="BAF90182">
        <property type="protein sequence ID" value="BAF90182"/>
        <property type="gene ID" value="AZC_4184"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4184"/>
    <dbReference type="eggNOG" id="COG5487">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_187346_0_0_5"/>
    <dbReference type="OMA" id="EIAWILF"/>
    <dbReference type="OrthoDB" id="2092958at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01361">
        <property type="entry name" value="UPF0391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009760">
        <property type="entry name" value="DUF1328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07043">
        <property type="entry name" value="DUF1328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036466">
        <property type="entry name" value="UCP036466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-1003">Cell membrane</keyword>
    <keyword id="KW-0472">Membrane</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0812">Transmembrane</keyword>
    <keyword id="KW-1133">Transmembrane helix</keyword>
    <feature type="chain" id="PRO_1000073379" description="UPF0391 membrane protein AZC_4184">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="4"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000255" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01361"/>
        </source>
    </evidence>
    <sequence length="59" mass="6288" checksum="2FEDA5A18769DBCA" modified="2007-12-04" version="1">MLSWALTFLVVAIIAAVLGFTAVAGTAIEIAKIIFYVAIVLFLISAVMGFLRRGSSRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="77" xmlns="http://uniprot.org/uniprot">
    <accession>A8HT54</accession>
    <name>A8HT54_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_4257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172777.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4257"/>
    <dbReference type="EnsemblBacteria" id="BAF90255">
        <property type="protein sequence ID" value="BAF90255"/>
        <property type="gene ID" value="AZC_4257"/>
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    <dbReference type="KEGG" id="azc:AZC_4257"/>
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        <source>
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    <sequence length="304" mass="31898" checksum="09913903C35D3B4F" modified="2007-12-04" version="1">MLFNQAGGAQTAAQGAGDGLVIDTTTQTFMADVIEESRTRPVLVDFWAPWCGPCKTLGPVIEKAVRSKKGKVLLAKMNIDDHPAIAQRLGIQSIPAVYAFVNGQPVDGFMGALPEGQVNDFIERLTGADAGIAEILEAAEQALAEGDAVGAGNAFAQILAEEPDNLKALSGLARAHVLLGDLEQAEATLAGVPANKANDPAVASARAAIELARQTADLGETAELEAAVAADPANHQARFDLALALAAGGKREDALVHLLEIVKRDRSWNEDGARKQLVQLFDAWGPTDPLTVTGRRKLSAILFA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3" key="2">
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90265.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_4267"/>
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        <property type="gene ID" value="AZC_4267"/>
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    </dbReference>
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        <property type="entry name" value="AB_hydrolase"/>
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        <property type="entry name" value="Hydrolase_4"/>
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    <dbReference type="Pfam" id="PF12146">
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="38"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="313" mass="34339" checksum="E689D6DBCA859ECF" modified="2007-12-04" version="1">MSLYPIPSNPVPEGAVTGVFTTADGRSLRFARWRPEGAQGTVALFPGRAEFIEKYFEVVRELLERRFAVAIFDWRGQGGSQRLLRNPRKGHVRRFSDYQLDLDAFGRQVLLPDCPAPHYALAHSMGGTILLQAVLDGRRWFDRVVLSAPMLDIAMVPYPRATHATARFLRGLGLGRAFVPGGGSAIVTNQPFEGNLVTSDPERYARAAAVTAKTPDLGLGSPTIGWLAGAYDAMEMLRQPEALREIRQPLLVVAAGAERIVSNAAIEHVASRLIAGAYVTVPAARHEILMERDIFRAQFWAAFDAFIPGSSPF</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="84" xmlns="http://uniprot.org/uniprot">
    <accession>A8HTB5</accession>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            </authorList>
            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
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        <property type="protein sequence ID" value="BAF86816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
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        <location>
            <begin position="11"/>
            <end position="252"/>
        </location>
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    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
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        <ligand>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
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            <dbReference type="ARBA" id="ARBA00022840"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="266" mass="28555" checksum="E1A6F5755790B40C" modified="2007-12-04" version="1">MRTGPMPEPKIEVAALRKCFGDLEVLKDINLRVDAGGVVALIGPSGSGKSTLLRCMNLLVLPDGGRVRVGGDSFAFGSGDRLPGVKEIARFRANTGMVFQHFNLFPHMSVLANVMEGPLTVRGMKKAQAEPLARRLLSKVGLADKADAYPSKLSGGQKQRVAIARALAMEPEVMLFDEATSALDPELVGEVLNVMRGLAAEGMTMVIVTHEIAFAREVADRVVFMRDGVVVEEGPAREVIDTPREAATRAFLSHFHKRGEAPAPSA</sequence>
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        <name evidence="1" type="ordered locus">AZC_0846</name>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="protein sequence ID" value="BAF86844.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0846"/>
    <dbReference type="EnsemblBacteria" id="BAF86844">
        <property type="protein sequence ID" value="BAF86844"/>
        <property type="gene ID" value="AZC_0846"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0846"/>
    <dbReference type="eggNOG" id="ENOG50308VJ">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_043375_0_0_5"/>
    <dbReference type="OMA" id="SIVCRGD"/>
    <dbReference type="OrthoDB" id="161412at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF86844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="483" mass="52454" checksum="6BB2F7E110611184" modified="2007-12-04" version="1">MLAFGEYRPDVSDYNGQHSQTMLNVFPRGDGYGPVASIEALTDALPAPCRGYIRAINEDGSVTIIAGTANGLWRLNNTTFAWEDVSKGPYNLTGSDLWSFAQFDNRVVAAQIGDPMQVITLGAGSTQFEDLAGDPPQARYVSVVSRFLVASGLLGAPLRIQWSAIDNIEGWTSGTDQSDFQDFADGGAVQGVAGGELGIVFQENAIRRLIYSPGSAVIFQIDKVPGETGCAVALSITQAAGYVFWYAGSGFYRMNPAGAPEPIGKERVDRTFAADFNADNLQLMMGAADPRSSRIIWAYRSQSGAAGRFDKALAYDYLLNRWTPLQFQGEFIAPFAQPGMTLERLDAAYPEYNLDTLPFSLDSFPASGGLLMAAFDAQHRLGLFTGPNLEATLVSAEGGGAQRAMIKAAMPVTDATEVMASISQRSTLMDAGEWSRETTRNILGWCPIRRDTRFYRFKLRFRKGARWTFCTGVEVDAVPTGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVK0</accession>
    <name>A8HVK0_AZOC5</name>
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        <recommendedName>
            <fullName evidence="1">LPS-assembly protein LptD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lptD</name>
        <name evidence="3" type="ordered locus">AZC_4323</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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            <taxon>Bacteria</taxon>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Component of the lipopolysaccharide transport and assembly complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the LptD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172843.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4323"/>
    <dbReference type="EnsemblBacteria" id="BAF90321">
        <property type="protein sequence ID" value="BAF90321"/>
        <property type="gene ID" value="AZC_4323"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4323"/>
    <dbReference type="eggNOG" id="COG1452">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009039_3_0_5"/>
    <dbReference type="OMA" id="DYSHLDW"/>
    <dbReference type="OrthoDB" id="100018at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015920">
        <property type="term" value="P:lipopolysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010033">
        <property type="term" value="P:response to organic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01411">
        <property type="entry name" value="LPS_assembly_LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020889">
        <property type="entry name" value="LipoPS_assembly_LptD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007543">
        <property type="entry name" value="LptD_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04453">
        <property type="entry name" value="LptD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="LptD" evidence="2">
        <location>
            <begin position="324"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="825" mass="90438" checksum="D89AC66DB8BE5162" modified="2007-12-04" version="1">MTVGSSPFQALAVMGPRSVLRGMGTAFVAGLLLLGASAGAVTPARAQSGPAGLGVATPKTDPNAKMLVTADQLVYDYKNDTVSAVGNVQMYYDGSSVEAKRVTYNRKTNKVIAEGNVRLKQKDGKIVTAENLELSQDYSEGFINSLRVDTPDKTHFAATRADRAEGNITVFQNGVYTACEPCKDTPQKPPLWQIKAARIIHNEDEKMIYYQDATMEFFGMPIAYFPYFSSPDPTVKRKTGFLFPEFYSSGNTGYGVSVPFFWNIAPDRDVTFDPMFFSKQGVLLRGEWRQRLENGSYSLRAAGIDQLDKGTFVSNGTPLPGYRDQRGMVESHGQFALNNYWTFGWDGTVVSDRMFLRDYGFVSSDIIDRTSQVYLQGQGDRSYFDLRGLYFLGMATTDNQNKLPVVGNLDYNYVFGKPVLGGEAGVNVNFTTLSRDQADFISTNALTANAANIGVLGGSCALSNPNPTQCLLRGAPGDYTRLSAELYWKRTLVDSAGQMWTPFAQMRVDVAQANVSALPTSYSSGPTLPGQNPLQSGDESLIRAMPVIGLDYRYPFISVQSWGTQTIEPRVQLIARPNETGIGKLPNEDAQSLVFDDTNLFSINKYSGYDRVEGGGRANVGVSYTAALNQGGVITALVGQSYHLFGLNSYAQGDMANTGLQSGLDTNVSDYIARFSYSPTDKFEVISRFRFAEDNASLQRFELEGRTQIDKLGINVIYGRYAPQPLLGYYEEREGVFTSASYKLSENWSLNGAVRYNIAQSAFDYTQLGVSYMDDCFTLALNYISDYTVNGTTNSSNNSILLRIGLRTLGETNIKSGLGSSSSSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8HVT6</accession>
    <name>A8HVT6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH-ubiquinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_4356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012172876.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4356"/>
    <dbReference type="EnsemblBacteria" id="BAF90354">
        <property type="protein sequence ID" value="BAF90354"/>
        <property type="gene ID" value="AZC_4356"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4356"/>
    <dbReference type="eggNOG" id="COG3261">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="eggNOG" id="COG3262">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_015134_3_1_5"/>
    <dbReference type="OMA" id="CDPCFTC"/>
    <dbReference type="OrthoDB" id="473681at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037232">
        <property type="entry name" value="NADH_quin_OxRdtase_su_C/D-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143243">
        <property type="entry name" value="SSF143243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="Complex1_49kDa" evidence="1">
        <location>
            <begin position="272"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF90354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="504" mass="54244" checksum="53928C626DFE3552" modified="2007-12-04" version="1">MGALTDILATGRIRTDHRPWLRAEVDAATWEALSEGLAAGRWTLMALWGEPDAVHMALLDEAATSLGTATYLAGDGTFPSVGRHHAPAQRLERTIRDLYGLVPVEAPDTRLWLDHGRWPVSRPLSGAPIPPDTTPYAFLPVEGQGLHEVAVGPVHAGIIEPGHFRFTANGEAVVRLEERLGYVHRGIEGLMRGASLERAATLAGRVSGDSTVAYALAFAGAVEAALEMEAPPRARWLRGLMAELERLANHFGDIGAVCNDAAFARMLAPCAVLREQVLRASEAAFGQRMMRDLVVPGGVLIDLAPRGEGRLRSLVETARSALPELLALYDGTASLQDRTVGTGIAQPDLVRRFGCGGFVGRASGRGFDVRRTLPYAPYDALRFDVAVLEAGDVDARVRIRFSEAEESLSLITQMLSNMPDGGDLSSPLPQSGAAREGVALVEGFRGDVFAFVRLDAAGRVAHAHLRDPSWFQWPVLEAVIEGNIIADFPLCNKSFNCSYAGHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="87" xmlns="http://uniprot.org/uniprot">
    <accession>A8HW95</accession>
    <name>A8HW95_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid ABC transporter, permease protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ordered locus">AZC_4406</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="11" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10 11" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="10 11" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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            <topology evidence="2">Multi-pass membrane protein</topology>
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        <subcellularLocation>
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        </subcellularLocation>
        <subcellularLocation>
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    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.</text>
    </comment>
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        <property type="protein sequence ID" value="BAF90404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
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        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
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        <property type="entry name" value="MetI-like"/>
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        <property type="entry name" value="BPD_transp_1"/>
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    </dbReference>
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        <property type="entry name" value="HEQRo_perm_3TM"/>
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    </dbReference>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    <evidence type="ECO:0000256" key="2">
        <source>
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        <source>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
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    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
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            <dbReference type="EMBL" id="BAF90404.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="217" mass="23685" checksum="4518EA8F12937433" modified="2007-12-04" version="1">MIRQFTSAEFMFLLMAVRWTLLLSAIAFLGGAVGGLFVALARTSQWAWLRAIAGAYIQVFQGTPLLMQLFLVFFGANFFGLSIDPLMAAAIGLTLNGAAFLGEIWRGCIQAIPKGQWEAATALGLHYTTRMKEIILPQAAKIAVAPTVGFLVLLVKSTSLASIIGFVELTRAGQIVNNATFRPFLVFGIVAAIYFVLCWPLSLFSRRLEKKFGTVSR</sequence>
</entry>
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        <name evidence="3" type="ordered locus">AZC_4414</name>
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    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4414"/>
    <dbReference type="EnsemblBacteria" id="BAF90412">
        <property type="protein sequence ID" value="BAF90412"/>
        <property type="gene ID" value="AZC_4414"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4414"/>
    <dbReference type="eggNOG" id="ENOG502ZKHW">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_686336_0_0_5"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="entry name" value="YcxB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14317">
        <property type="entry name" value="YcxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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    </feature>
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        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="YcxB" evidence="2">
        <location>
            <begin position="128"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="401" mass="44311" checksum="C6665365529F57C9" modified="2007-12-04" version="1">MTQPSPAAPVSLPIPLPLTLHINLTLDDMAEATLAAAHPEMARNRQHMLTRGLTVVLAAFIVIMGLSSGFSPTVLFHVVWGTPLLYLLLCMAPIILLWVLHPRLAMRGMRTMLRDGGVREAWAATLQITEEGITSTEPDRTTFVPWHRFRSVDETPRLVVCALWPYESTILPKAAIPADIAPALISWMAAQIAAPAAGATPEIPPAPETAVRVTHSLTPDDYAEALTWQRDQPAARRRTRRHYMLFWVLGSLLLPLFILLLVLTDPRPMEWEKITFLAERMVPDLLRNTLVLGVATFGFYLFRRRMAARAARKMATRNAAQFDAGPITTTFAPDGITIVQGGAMSRYGWPMVMALGETLSHVLVPLRSYGILAILREDLDPAARQRLLDMARAAGVPTTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-01-19" version="47" xmlns="http://uniprot.org/uniprot">
    <accession>A8HWL4</accession>
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        <recommendedName>
            <fullName evidence="4">Lectin-like protein BA14k</fullName>
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        <lineage>
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    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="10" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9 10" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Has immunoglobulin-binding and hemagglutination properties, and can bind to mannose. Essential for virulence. May be involved in LPS biosynthesis or polysaccharide transport.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BA14k family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF90443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4445"/>
    <dbReference type="EnsemblBacteria" id="BAF90443">
        <property type="protein sequence ID" value="BAF90443"/>
        <property type="gene ID" value="AZC_4445"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4445"/>
    <dbReference type="eggNOG" id="ENOG50331V1">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1264783_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012413">
        <property type="entry name" value="BA14K"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07886">
        <property type="entry name" value="BA14K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0843">Virulence</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF90443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="218" mass="22791" checksum="929250E8B15A3DEC" modified="2007-12-04" version="1">MRSLASWAPVHGPVTQWHLPAAEAFILRKETEMTQNIGAFRRTSSIILAAAVAGSLGLPGAAQAQMARAGATNAGAMQIGGGTSVPVQQVQYPLAPNAPRVGPPPPRGWRGNGPRAGWRGPGWRGPGYYQRGWGGPGWRGPGYYGPRYYNYNNNGAAVAAGVIGGLALGAAAASAANANQANQANAANWQAYCASKYRSFDPRTGTYLGYDGLRHPCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="88" xmlns="http://uniprot.org/uniprot">
    <accession>A8HX19</accession>
    <name>A8HX19_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1452</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1452"/>
    <dbReference type="EnsemblBacteria" id="BAF87450">
        <property type="protein sequence ID" value="BAF87450"/>
        <property type="gene ID" value="AZC_1452"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1452"/>
    <dbReference type="eggNOG" id="COG1126">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000604_1_22_5"/>
    <dbReference type="OMA" id="PEVMFFD"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="17"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="257" mass="28541" checksum="FD9A106D0163DAC6" modified="2007-12-04" version="1">MTPHVANLSGTAVDAMIVMADVEKWYGAYKALSGINLEVRRGERIVLCGPSGSGKSTLIRCINHLEAYQKGEIRVGGTRLGDDSRTIDKVRREVGMVFQHFNLFPHMTVLENCMLAPVRALGVSRKEAEETARGLLERVKILEQADKYPAQLSGGQQQRVAIARALCMRPSVMLFDEPTSALDPEMVKEVLDTMIGLAEEGMTMICVTHEMGFARQVADRVIFMAGGAIVEEAPPQEFFTRPRHERTRKFLGEILSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="66" xmlns="http://uniprot.org/uniprot">
    <accession>A8HXB9</accession>
    <name>A8HXB9_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
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        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
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    </evidence>
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    </evidence>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
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    </evidence>
    <evidence type="ECO:0000256" key="7">
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    </evidence>
    <evidence type="ECO:0000313" key="8">
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    </evidence>
    <evidence type="ECO:0000313" key="9">
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    </evidence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
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    <evidence type="ECO:0000259" key="1">
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    <sequence length="284" mass="32701" checksum="53BF26674E0DF49B" modified="2007-12-04" version="1">MIWENLVCLNSDVEPSFEVLGPARDYHATDSRLGDWTALDYKAALERDTAPLPLTSDREGYYGPDHFSYWASGLADARYLLEAAAQLGVDPQYYLDMGCASGRVLRHMAHERQGMRALGCDINRLHVEWCNRYLPANCTVFQNHSIPSLPLPDNSVDIVSAYSVFTHIEALETAWLMELRRILRPGGVAWITVHSELTLQDMTTDWPLWNPTMSHPEAATKLDAQRNFVGDRMVLRWHSDRSYASNVFYKLDYLKKTWSRFFEIADVRRRFPTFQDVLILRKPA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87561">
        <property type="protein sequence ID" value="BAF87561"/>
        <property type="gene ID" value="AZC_1563"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1563"/>
    <dbReference type="HOGENOM" id="CLU_1792508_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="144" mass="15910" checksum="C1D9DECCB8357C6E" modified="2007-12-04" version="1">MIVAVIAPAMKSRSKTVFWFKITGVTLALLMLLGIGVCRAFRTVAQVERPLFEVHVSPADACEAVRRKVIEQLDGRHPVSRSGCPGAKSSVWHDPANHVFIIVDQMDVQDQRGTPSVVRFQATARYTVAEDGRVHWTTISVTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8HZF5</accession>
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        <submittedName>
            <fullName evidence="1">3-hydroxybutyrate dehydrogenase</fullName>
        </submittedName>
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    <gene>
        <name evidence="1" type="ordered locus">AZC_4577</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <dbReference type="PubMed" id="17720818"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
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            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <dbReference type="STRING" id="438753.AZC_4577"/>
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        <property type="gene ID" value="AZC_4577"/>
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            <dbReference type="EMBL" id="BAF90575.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    </evidence>
    <sequence length="261" mass="27244" checksum="5718E26FF23BEA7A" modified="2007-12-04" version="1">MSIKGKVAVVTGSTSGIGLAYARAFAAEGANVVINGLGDAAAIEAERAKIEADFGVKALYSDANMLKAEEITGMVKLAETELGACDILVNNAGIQHVAPVEDFPIDTWNTIIAINLTSAFIASKAAIPGMKAKKWGRIINTASAHALVASPFKSAYVSAKHGIAGLTKTIALETATFGITCNAICPGYVWTPLVEKQIPDTAKARGMTEEQVKKEVLLAAQPTKEFVTVEEVAALAVFLASDNARSITGAMHQIDGGWVAE</sequence>
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<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Yamada M."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
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        <property type="gene ID" value="AZC_1308"/>
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            <begin position="16"/>
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    <evidence type="ECO:0000256" key="1">
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    </evidence>
    <evidence type="ECO:0000259" key="2">
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    <sequence length="308" mass="33818" checksum="4F196B0C0DA7A8E3" modified="2007-12-04" version="1">MSAQNRSLISNVMSSLNYNHLRYFWAVAHDGNLTRTAERLNLTQSALSVQIRKLEDRLGHALFERRGRQLHLTEAGKIVLDHADAIFATGDELLGTLRQTGAARQALRVGSLATLSRNFQMEFLRPVLGRTDIDLVLRSGSVGELLRALEALNLDVVLLNQAPPGDALTPFVTHRLAERPVSLVGTPERLRHAASFADRLRSHPIILPTVDSSVRIGFDALADRLGVRPQIVAEVEDMAMMRLLAREDIGLAVLPSIVVKDEIAAGVLVEGDQLSDIVETFHAVTMSRRFPNPLVKLLLQPTGTSGDN</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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            <end position="161"/>
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    <evidence type="ECO:0000259" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87380.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="171" mass="18747" checksum="5675509348D3E24B" modified="2007-12-04" version="1">MLTRKYSSSSFLVNKEDAMLEAAPVADLTSHLGYWLRLVSNHVSHAFARKLEAEGVTVAEWVLLRELYGVPSLGPSRLADTMGLTRGAISKLADRLIRKQLVVREDRADDARAHLLALTPAGRDLVPRLAAHADTNDAAFFGHLTREERAALEGLLKTIALKRGLKAMPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="71" xmlns="http://uniprot.org/uniprot">
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
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    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1408"/>
    <dbReference type="EnsemblBacteria" id="BAF87406">
        <property type="protein sequence ID" value="BAF87406"/>
        <property type="gene ID" value="AZC_1408"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1408"/>
    <dbReference type="eggNOG" id="COG0129">
        <property type="taxonomic scope" value="Bacteria"/>
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        <property type="component" value="Chromosome"/>
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        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
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    <dbReference type="Pfam" id="PF00920">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
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    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87406.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="557" mass="59103" checksum="779150355A9C0FE2" modified="2007-12-04" version="1">MRRNLASYGDPGFSLFLRKAFIKAAGYSDDALDRPIIGITNTFSDFNPCHGNVPRLIEAVKRGVMLAGGLPMEFPTVSIHESFSNPTSMFLRNLMAMDTEEMIRAQPMDAVVLIGGCDKTVPAQLMGAVSANVPAIQLITGPMLVGHHKGEILGACTDCRRLWGQHRAGHLDAEEMDVLSGRLAPTQGTCMVMGTASTMGCLVEALGIALPWTGTIPATHADRIRAAEASGRQAVQLATHGPTPRDLLTPAAFRNALTVLQAIGGSTNGLVHLAAIARRAGLSVDLDAFDAIGRSVPVLIDLKPSGDHYMEHFHWAGGVPKLMKELGDHLDRSAPTIDGRTIGEIADAAEEVPGQAIIRPASAPLKPFGGMAVLRGNLAPGGAVIKHSAASEALLRHTGRAVVFDSVEDMVNRIDDPGLDVQADDVLVLRNAGPKGAPGMPEAGYLPIPKKLAQAGVKDMVRISDARMSGTAFGTIVLHITPEAAVGGPLGLVRSGDTIRLDVAAREIALLVPDEELERRRAEWTPPAHLAEAARGYQHLYLTHVLQADEGCDFDFC</sequence>
</entry>
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    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_4675"/>
    <dbReference type="EnsemblBacteria" id="BAF90673">
        <property type="protein sequence ID" value="BAF90673"/>
        <property type="gene ID" value="AZC_4675"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_4675"/>
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        <property type="component" value="Chromosome"/>
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        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
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        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
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    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
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        <property type="entry name" value="Glutathione_S-Trfase_N"/>
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        <property type="entry name" value="GST_C"/>
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        <property type="entry name" value="Thioredoxin-like_sf"/>
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    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
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        <property type="match status" value="1"/>
    </dbReference>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="88"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF90673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="230" mass="26361" checksum="557D997ED0F7121D" modified="2007-12-04" version="1">MIQLYHHPFCPHSRFIRLLLAEYGIEPELIEVRVWERDPDFLALNPANETPVLTEEHVPSAPGASIIAEYLDETRGLALADRRLLPHAPLERIEVRRLVAWFHEKMFLDVTEHLVRERIYKRYMRANQGGGPPDATALRAARSNIRYHLKYIGWLAKARNWLAGERLTHADLAAAAHLSVADYLGDVPWDEDEDAKAWYARVKSRPTFRGILADTMPGMPPSATYTDLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="86" xmlns="http://uniprot.org/uniprot">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
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            <taxon>Alphaproteobacteria</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="31"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF87845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="405" mass="44547" checksum="C21E0DEC2324124C" modified="2007-12-04" version="1">MTDFHRIRRLPPYVFEQVNRVKAAARNNGVDIIDLGMGNPDLDAPAHVIEKLKETIGKPRTDRYSASKGIPGLRRAQAAYYERRFGVKLNPETQVVATLGSKEGFANMAQAITAPGDVILTPNPSYPIHAFGFLMAGGVIRSVPVEPDAQFFHAMERAVQHSIPKPIAVVVCYPSNPTATVANLDFYKDVVAFAKKNDLIVLSDLAYAELYFDDNEPPPSVLQVPGAMDVTVEFTSMSKTFSMAGWRMGFAVGNERLIAALARVKSYLDYGAYTPIQVAATAALNGPQECIAEMRETYKRRRDAMVDSFGRAGWTIPVPKASMFAWAPIPEPFRAMGSVEFSKLLIEKAEVAVAPGVGFGEHGDEYVRIAVVENEQRIRQAARNIRRFFEQAGTLHNVVPLSAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2H2</accession>
    <name>A8I2H2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Molybdopterin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1874</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1874"/>
    <dbReference type="EnsemblBacteria" id="BAF87872">
        <property type="protein sequence ID" value="BAF87872"/>
        <property type="gene ID" value="AZC_1874"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1874"/>
    <dbReference type="eggNOG" id="COG0243">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_000422_13_3_5"/>
    <dbReference type="OMA" id="DMNEIAR"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02793">
        <property type="entry name" value="MopB_CT_DMSOR-BSOR-TMAOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041954">
        <property type="entry name" value="CT_DMSOR/BSOR/TMAOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041460">
        <property type="entry name" value="Molybdopterin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006655">
        <property type="entry name" value="Mopterin_OxRdtase_prok_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18364">
        <property type="entry name" value="Molybdopterin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00932">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Molybdopterin_N" evidence="7">
        <location>
            <begin position="57"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Molybdopterin" evidence="5">
        <location>
            <begin position="100"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="Molydop_binding" evidence="6">
        <location>
            <begin position="669"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="816" mass="88562" checksum="C019E2BD1A4BD278" modified="2007-12-04" version="1">MSNNPGFSKGRRLHIGLIQPRAAILMDSFHRSTRHAGRGLAEPQMPRNPSIAAGASHASHWGSFSARWDGDRVQLTPHPEDPAPSPILGNFADALRHQARILRPMVRRGWLDHGPGPRHRDFSNDLVPVSWETALSLVATEIARVRDSYGPEAVYGGSYGWSSAGRFHHAQSQIHRFHNVVCGGYVRSVNSYSAGASAVILPRVMGPFEPLSRHNVTWDQICAHTDMVLAFGGMPIKNSMIASGGITRHVEADAMARAAARGTEFWSVSPLRDDMPEAAEARWLPIRPGTDVAMMLGLAHTLLTEALYDSSFVARYCVGFERFASYLTGEADGLPKSADWAAEITGIGADAMRMLARRLVEGRSLITVAHSLQRAQFGEQPVWMAATLAAMVGQIGLPGGGFNYALGAMGHTGRQINAVPIPTLPQGRNGVSTFIPVARIADMLLNPGGVFAFNGATYVYPRVRLIHWAGGNPFHHHQDLNRLRRAFSEADTIIVQESAWTPMARFADIVLPVTMTLEREDIGAAATDPRLIAMRQVAPPIGEARDDFVIFSALAARLGLEAAFTEGRSVREWLAHLYEQTQEALENAGLFAPSFEEFWERGEIPLPSAPDDGGLLRAFRADPQAAPLPTPSGRIEIFSETIAGFGYDDCPGHPTWLPSEEQPSAQTPLTLVANQPATRLHSQLDFAAHSQSHKQKGREVVRINPNDALERGIGDGDLVRLFNARGACVASARLSADVMPGVLHLPTGAWYDPEDEAPEGPLCVHGNPNVLTRDVGTSQLAQACCGQVTVVDIARHDRPVREVLAHRPPAFAEAAP</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="74" xmlns="http://uniprot.org/uniprot">
    <accession>A8I2M2</accession>
    <name>MQO_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable malate:quinone oxidoreductase</fullName>
            <ecNumber evidence="1">1.1.5.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">MQO</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Malate dehydrogenase [quinone]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mqo</name>
        <name type="ordered locus">AZC_1899</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-malate + a quinone = a quinol + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:46012"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.1.5.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MQO family.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.4" evidence="1"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170427.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8I2M2"/>
    <dbReference type="STRING" id="438753.AZC_1899"/>
    <dbReference type="EnsemblBacteria" id="BAF87897">
        <property type="protein sequence ID" value="BAF87897"/>
        <property type="gene ID" value="AZC_1899"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1899"/>
    <dbReference type="eggNOG" id="COG0579">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_028151_0_0_5"/>
    <dbReference type="OMA" id="RCDNPEV"/>
    <dbReference type="OrthoDB" id="1371190at2"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052589">
        <property type="term" value="F:malate dehydrogenase (menaquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008924">
        <property type="term" value="F:malate dehydrogenase (quinone) activity"/>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <property type="entry name" value="RmlC-like_jellyroll"/>
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        <property type="entry name" value="SSF51182"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
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    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF87898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="131" mass="14317" checksum="8DC7FBDB5DE5F434" modified="2007-12-04" version="1">MIRCVRMWTGPDGNSLFEEGTLEIGAGQHGKASGLPIAVHELSFQETASGGSFEWHQDPQPQFVITLAGTIEFEVKSGATFTIHPGDVLIAQDDSGSGHRWRLIGDQPWRRAYVIYDPGTNLHFKPNGAQA</sequence>
</entry>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
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        <text evidence="1">Acts on leucine, isoleucine and valine.</text>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00014472"/>
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    </evidence>
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            <dbReference type="EMBL" id="BAF87961.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="284" mass="30812" checksum="EF8C48FBC187A87F" modified="2007-12-04" version="1">MDRIAYVNGDFVPLAEARISPLDRGFLFADGIYEVSAVLDGKLVDNDSHLARLKRSVGEIALDLPVTLEELVELERELVRRNSLTEGVVYMQVTRGVADRDFTFPKDAKPTLFMFTQEKNILASKAAETGIRVKSVPDLRWARRDIKSVALLAQVLAKQAAAEAGCQEAWMVQDGFITEGGSSSAFIITANDVVVTRPNSTAVLPGCTRRALLALAAEGTITVEERLFTLDEALAAKEAFIASASSFVQAVVAIDDKPIGTGTPGPLTKRLRELYIAFARQTAV</sequence>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170547.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2020"/>
    <dbReference type="EnsemblBacteria" id="BAF88018">
        <property type="protein sequence ID" value="BAF88018"/>
        <property type="gene ID" value="AZC_2020"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2020"/>
    <dbReference type="eggNOG" id="COG0154">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_009600_0_4_5"/>
    <dbReference type="OMA" id="DRSDWYR"/>
    <dbReference type="OrthoDB" id="1239251at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="25"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF88018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="497" mass="52424" checksum="3E28DAD6FB4A58CD" modified="2007-12-04" version="1">MTELCDLTALELRDAIAHKRLSPVEVLEACLDRIEAVNPAVNAMVTLDVEGARKAAVEAEAAVMRGDALGPLHGLPLAVKDTQDVGGMRTTYGSPLFAEHVPAADAGSVARLRAAGAIIVGKTNTPEWAAGANTRNPVYGATGNPFDPLKSCAGSSGGAAVALACGMTPLATGSDTGGSLRNPAGFCGIVGMRPSYGLVASERRLHGWSSLSTDGPMARNVSDTALMLSVMASDDSRDPLAYTLPGEPVRARPGRWTVPEINLKELRLAFTEDFGFAPTEQQIRRVFRSRVAALAPHFATAEEAGPDCTGADDAFAVLRASMFLSMFEKIHAEKPHMLGPNVTANVKEGLSYSLSDYARAAATQTRIYRSYQSFFATHDVLISPTITLSPRPWSEPHPAEIDGVPTRSYFHWLALAYAVTLAGHPAISLPLGVDEAGMPFGLQIVGPRGGDALVLGVAKALETVCASDAALCRPVPDLAGLKAARPLRETPGFMTWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3L8</accession>
    <name>A8I3L8_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ordered locus">AZC_1630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF87628">
        <property type="protein sequence ID" value="BAF87628"/>
        <property type="gene ID" value="AZC_1630"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1630"/>
    <dbReference type="eggNOG" id="COG0730">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_045498_6_0_5"/>
    <dbReference type="OMA" id="SHEAVMH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF87628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="283" mass="28787" checksum="AA311507B8C82F62" modified="2007-12-04" version="1">MLPAAMLATIPWSEILILCGALLAGGVASGILAGLLGVGGGGIIVPVLYEVFRIIGVSDDVRMQLCIGTSLAIIVPTSIRSFHAHKARGLVVPGLLKVLGPPAVIGVALGSAIAGMVNGKILQGVFIALSVVLAARSISGRTDWRLGDQLPGKATLRIWGFFIGMASSMVGIAGGGLSTILLTLYGVPIHAAVATSAGVGIFIPLPGVLGYAISGWPHLSDLPPLSLGYVSVIGFALMAPVSTLTAPIGARLAHRLPRRGLEVGFGVFLLAVAARFLVAILSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3N4</accession>
    <name>A8I3N4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Chitooligosaccharide deacetylase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nodulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ordered locus">AZC_1635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="9" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8 9" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the polysaccharide deacetylase family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1635"/>
    <dbReference type="EnsemblBacteria" id="BAF87633">
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        <property type="gene ID" value="AZC_1635"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1635"/>
    <dbReference type="eggNOG" id="COG0726">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="NDMKFFH"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10977">
        <property type="entry name" value="CE4_PuuE_SpCDA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
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    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017625">
        <property type="entry name" value="PuuE/SpCDA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0536">Nodulation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="7">
        <location>
            <begin position="82"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="BAF87633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="323" mass="35937" checksum="90548BF07FF11B20" modified="2007-12-04" version="1">MNRQWTLPHRTRSLAATEKRMRERDLMGYGGRPPAIVWPNGARVAVSLVVNFEEGAELAVGDGDAASERIGEVLSVVAPGRRDFGQEEIFAYGTRVGLWRFLDAFDRHERQATFYMCGRAVERLPALAAEIVARGHEPACHGWLWRPHADFTDAAEERASLVRCIDVIRDTTGQRPLGFCCRGSQSPHTRALLGELGFLYDSNGFDDDLPYWSAAADGRILVVPYAFDTNDMKFFHPNGFVEPGQFVRYIEAALGTLVEEAGRGRSSLLNIGLHLRICGRPARFAAVEGILSALRSLGDRVWVARRDEIARHWLSATARIGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="64" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3P6</accession>
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        <recommendedName>
            <fullName evidence="4">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ordered locus">AZC_1639</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5 6" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1639"/>
    <dbReference type="EnsemblBacteria" id="BAF87637">
        <property type="protein sequence ID" value="BAF87637"/>
        <property type="gene ID" value="AZC_1639"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1639"/>
    <dbReference type="eggNOG" id="COG1566">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_018816_6_1_5"/>
    <dbReference type="OMA" id="DAWAVFQ"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="75"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="179"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="BAF87637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="362" mass="38555" checksum="E5D963A5FEAC21DE" modified="2007-12-04" version="1">MPPAAAVSYGDLAQAMTRETPPTTEPELPAPSSSSGARAAAVVVALSICLVVGLSLWFLVQPDPLLVQGEADARRLDIAARVDGRISTRPADRGADMAQGAALVTIDNPQLLARLAEARAAKVVAEADLERIRVGTRAEVIAARKAAVAAADASAKLAQQTYDRTRQLTERDFASVQKLDEATASLDVARRALDQARLAQDEAIAGYTAEERGVAEAAVAKADAAIRTLQAQVDELVVKAPAATQVYQVNAEPGEYVSPGVPLLSLVDLSDVWVRFDLREDLIGGLKPGDRFTVRIPALGDRPVTVEVRTIATRGEYAGWRATRATGDFDLRTFEVRAYPVAPLAGLRPGMSAYAEWKRPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I3R7</accession>
    <name>A8I3R7_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1646</name>
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    <organism evidence="1 2">
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        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
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                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="12 13" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a quinone + 5 H(+)(in) + NADH = a quinol + 4 H(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:57888"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="8">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the complex I 75 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF87672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170202.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_1674"/>
    <dbReference type="EnsemblBacteria" id="BAF87672">
        <property type="protein sequence ID" value="BAF87672"/>
        <property type="gene ID" value="AZC_1674"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_1674"/>
    <dbReference type="eggNOG" id="COG1034">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="HOGENOM" id="CLU_000422_11_6_5"/>
    <dbReference type="OMA" id="HKNVGPL"/>
    <dbReference type="OrthoDB" id="323168at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
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        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
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        <property type="entry name" value="Mopterin_OxRdtase"/>
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        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
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        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
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    <dbReference type="InterPro" id="IPR010228">
        <property type="entry name" value="NADH_UbQ_OxRdtase_Gsu"/>
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    <dbReference type="InterPro" id="IPR015405">
        <property type="entry name" value="NuoG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10588">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09326">
        <property type="entry name" value="NADH_dhqG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00929">
        <property type="entry name" value="NADH-G_4Fe-4S_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01973">
        <property type="entry name" value="NuoG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS51839">
        <property type="entry name" value="4FE4S_HC3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00642">
        <property type="entry name" value="COMPLEX1_75K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00643">
        <property type="entry name" value="COMPLEX1_75K_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0874">Quinone</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="9">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S His(Cys)3-ligated-type" evidence="11">
        <location>
            <begin position="87"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="10">
        <location>
            <begin position="224"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="BAF87672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="76" xmlns="http://uniprot.org/uniprot">
    <accession>A8I4A2</accession>
    <name>A8I4A2_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase/reductase SDR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_1708</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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    <sequence length="249" mass="25292" checksum="EB02D47A7D190792" modified="2007-12-04" version="1">MTTFQNKVVVVTGGTSGIGLATAKAFSAAGASVFITGRRQEALDAAVKAIGGQVTGVRGDMSKLADIDRLYDAVQQRHAQIDVLFANAGGGGFAPLGAIDETHFDETFATNVKGVLFTVQKALPLLKDGGAVVLTGSTAGASGTPAFSVYGATKAAVRSFARNWVLDLKDRHIRVNVVSPGPIDTAGLNELFGGGAEADGVKAGLVGAIPSGRVGQPEEVAQAVLFLASDAASFINGAELFVDGGMTQI</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <property type="protein sequence ID" value="BAF87801.1"/>
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    </dbReference>
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        <property type="nucleotide sequence ID" value="NC_009937.1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
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    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF87801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="223" mass="23516" checksum="4F5B82E03158FF38" modified="2007-12-04" version="1">MFIVNPMPAQIAPELVTELEKCEVATIGHVLHSGFVDREIRAVLPGKRVAGTAVTLRIPHADSTLLHYLTAYVRPGDVVVIERCGDDKHACWGGVITNAMKMAGVKAGVIDGPATDFSEIVKVDMPMWCRGPSPITTKLLGLEGAMNVPVNVGGQTIEPGDAVLCDESGVVVLKPAQAPAIAARAIQMQENEIKLLARLAAGEKLPDITGARAMVEAKLAPAT</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <location>
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        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Fe cation</name>
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        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Fe cation</name>
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        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR002825-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="342" mass="36390" checksum="FBED061D6549A51D" modified="2007-12-04" version="1">MLRSIGRRLFLAACGTAMLVGTASAQQVVNVYTTREPALAAPLFEAFTKATGITVNSVFVKDGLAERVKAEGAASPADLLMTVDVGNLLDVVDAGVIQPVESKVLSDAIPANLRDPQGNWFALSMRARLIYAAKDMPKLTSFHYEDLSDPKWKGKICIRSGQHPYNIGLTAAYIVHYGEAKTEAWLRGLKANLARKATGGDREGARDIMGGICDIAVGNSYYVGLMRSGAGGPDQKKWGEAIDVVLPTFENGGTHVNVSGAAVAKNAPNKANAVKLLEFAVSPQMQAVYAKQNMEYPVLAGAEIDPIIAALGPLKIDSVSLVEVAKARKKASELMDKVGFDN</sequence>
</entry>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170790.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF88261">
        <property type="protein sequence ID" value="BAF88261"/>
        <property type="gene ID" value="AZC_2263"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2263"/>
    <dbReference type="eggNOG" id="COG1238">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_125997_0_0_5"/>
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    <dbReference type="OrthoDB" id="1928533at2"/>
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        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="61"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
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            <end position="115"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="146" mass="16002" checksum="D05225184C0405FA" modified="2007-12-04" version="1">MTGLAIYGGLFVTAFIAATILPLQSEAALVALLLTGDRPWWALVAAASAGNVLGSLTNWMLGRGIERYRDRKWFPADGKALDRAQRWYRRYGKWSLLLSWAPVVGDPLTVIAGVLREPLGSFLLLVGIAKVARYLILTALTLNLFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="67" xmlns="http://uniprot.org/uniprot">
    <accession>A8I5W9</accession>
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        <recommendedName>
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    <gene>
        <name evidence="4" type="ordered locus">AZC_2332</name>
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    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
            <taxon>Bacteria</taxon>
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            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
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    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14717"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.5.1.54"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the class-II DAHP synthase family.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88330.1"/>
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    <dbReference type="RefSeq" id="WP_012170859.1">
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    <dbReference type="STRING" id="438753.AZC_2332"/>
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    <dbReference type="KEGG" id="azc:AZC_2332"/>
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    <dbReference type="HOGENOM" id="CLU_026885_0_1_5"/>
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    <dbReference type="OrthoDB" id="1371606at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
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    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
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        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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        <property type="entry name" value="DAHP_synth_2"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01474">
        <property type="entry name" value="DAHP_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF88330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="479" mass="53032" checksum="4FFD5AEDB4BD9765" modified="2007-12-04" version="1">MTTRPVSDRNPSAEIVSRRAEGWRPDSWRFYPVVQVPDYPDKVALGEVEGKLASYPPLVFAGEARRLKAHLAKVAAGEAFLLQGGDCAESFDEHSADNIRDFFRVFLQMAVVLTFSGGSPVVKVGRIAGQFAKPRSAPTETVNGVELPSYRGDIVNDIAFTPDARIPDPHRQLEAYRQSAATLNLLRAFASGGYANLANAHQWMLGFVKDSPQSHRYQELANRITEALDFMRACGIDPQVHPEMRSTDFFTSHEALLLGYEQALTRVDSTSGDWYATSGHMLWIGDRTRQPDHAHVEYFRGIRNPIGIKCGPSLSADGLIRLLDVLQPDNEAGRITLICRFGAEKAAEHLPALVRAVQKEGRTVVWSCDPMHGNTIKAGSGYKTRPFDRILSEIRTFFDVHAAEGTIPGGVHLEMTGKNVTECTGGARAISDEDLRDRYHTYCDPRLNAEQSIELAFLVAELLKTARQSRGRREVVAAE</sequence>
</entry>
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        <submittedName>
            <fullName evidence="2">Putative acetyltransferase</fullName>
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    <gene>
        <name evidence="2" type="ordered locus">AZC_2059</name>
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    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <lineage>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2059"/>
    <dbReference type="EnsemblBacteria" id="BAF88057">
        <property type="protein sequence ID" value="BAF88057"/>
        <property type="gene ID" value="AZC_2059"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2059"/>
    <dbReference type="eggNOG" id="COG1670">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118917_0_0_5"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="198" mass="22233" checksum="782EEF601975BD2C" modified="2007-12-04" version="1">MKPLGLSPGRAPPMRNEGMQQEAVVRPSITFRLPTDADFPVLAEIRRDPHMQAMLMAIPDRTDDAAVRQWIERRVSEPNGLFRVICETQAQEALGFIQISQVNTRDLHGYGAVALSRRCTFPGAALLAMRELMRAARADLGLRKLMAEIRSDNVDAIRMNELCGYKVVGTLESHFADADNKRHDVLLLQRVLVSQRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="57" xmlns="http://uniprot.org/uniprot">
    <accession>A8I7V1</accession>
    <name>A8I7V1_AZOC5</name>
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        <submittedName>
            <fullName evidence="1">Putative phage late control gene D protein</fullName>
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    <gene>
        <name evidence="1" type="ordered locus">AZC_2167</name>
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    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
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    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012170694.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2167"/>
    <dbReference type="EnsemblBacteria" id="BAF88165">
        <property type="protein sequence ID" value="BAF88165"/>
        <property type="gene ID" value="AZC_2167"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2167"/>
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        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1340985_0_0_5"/>
    <dbReference type="OMA" id="GRWIKEW"/>
    <dbReference type="OrthoDB" id="1278199at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="204" mass="21511" checksum="70DEB4A562F8C885" modified="2007-12-04" version="1">MAIRKPIVIVEGPKTANLLSVWGDTLTSVRIRDAVGHESDTCTLTFRVSPPFPAMPPRGTRYTVRIGWAQNAMAKVGVYTVQRTGLAGNPDGGHLMTVECRAADLIEKAKSVDSGHWDNTTLGAIVADVAKGLGLKAAVDPKLKGIRIPYRARVNQEAMDFLSDLADDFGAAVKVAGGQIVMTERGAGRTASGGALPGLTIPYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="81" xmlns="http://uniprot.org/uniprot">
    <accession>A8I8C9</accession>
    <name>A8I8C9_AZOC5</name>
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        <submittedName>
            <fullName evidence="5">Transcriptional regulatory protein</fullName>
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    <gene>
        <name evidence="5" type="primary">gntR</name>
        <name evidence="5" type="ordered locus">AZC_2647</name>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
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                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu CT."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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    </dbReference>
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        <property type="entry name" value="G3P_DH_FAD-dep"/>
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        <location>
            <begin position="26"/>
            <end position="348"/>
        </location>
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        <location>
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            <end position="508"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
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    </evidence>
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    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361217"/>
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    </evidence>
    <evidence type="ECO:0000259" key="7">
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            <dbReference type="Pfam" id="PF01266"/>
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    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
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    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="BAF88707.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="516" mass="56809" checksum="B46E0720A17D1066" modified="2007-12-04" version="1">MINVVADGCTMVRQQGSGGDVSSPFDILVVGGGINGAGIARDAVGRGLSVMMVEQDDLAAHTSSWSTKLIHGGLRYLEYYEFRLVREALLERERLLAMAPHIIRPLRFVLPHDVSIRPAWLVRLGLFFYDHLAPRKRLPGCERINLSSDRRGAPLKPLTKVGFEYSDCAVDDARLVVLNALDAKERGAIVEVGTRLESARREGKLWVATLKDASGATREVRAKVLVNAAGPWVADVLNHRLGLNTSKGVRLVKGSHIVVPRLYEGTQAYILQNPDKRIIFAIPYQDDLTLIGTTDVPYTGAPQDVAISDDETDYLISSINHWFKREISRSDIVWDYSGVRPLFDDGSINASAVTRDYVFDIDAPEGQAPLLSVFGGKLTTYRKLAEHVMRDLAPHIPGLKPAWTAEGTLPGGDIPDGDADRYAADLLKRKPFLGADRARRLVHTYGTRVEAIVGGARSAEDLGRDFGGGLTEAELRYLKSAEWARTARDVLWRRTKLGLKLPKEAAAEIDAFLNSI</sequence>
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        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
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                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="6 7" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="PubMed" id="18522759"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="6 7" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="6 7" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial solute-binding protein 1 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171248.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2724"/>
    <dbReference type="EnsemblBacteria" id="BAF88722">
        <property type="protein sequence ID" value="BAF88722"/>
        <property type="gene ID" value="AZC_2724"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0574">Periplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008520"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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    </evidence>
    <evidence type="ECO:0000256" key="4">
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            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="BAF88722.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="353" mass="38695" checksum="474A3B3D5A53835C" modified="2007-12-04" version="1">MTEHRTSLSRRQFLAAGAALGAGAIAAPHVSRAQEAATLRITGWGGKWGQVMSADVVPAFEKEFKCKVVTDTALPFLPKLQASPRSAPIYDVLHTNSNEQWAAVEMGLVEPKIDPKLVPNLADVYPFAISDKIVGVSIFTSAIGLGMRTDKGYPTPTSWKDLWDERYNGVRGGYVIPVNSLGQAFVPMCGMLYGKGPTDLDAAYAALEKVKPIKLVDFTGAMEKMLLSGEVGMCIIHDSGINRYYDDKPPTAFVAPKEGVLALEQVLTITPGSKVKELANAYVNYMLSPDVQKKLAQAVWYSPSNKMVKLDEPYASRLLTTPEKVASLIQVDWKWYNAHKDAIDSRVNRIFRA</sequence>
</entry>
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    <accession>A8I902</accession>
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    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2727"/>
    <dbReference type="EnsemblBacteria" id="BAF88725">
        <property type="protein sequence ID" value="BAF88725"/>
        <property type="gene ID" value="AZC_2727"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2727"/>
    <dbReference type="eggNOG" id="COG3535">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_038930_0_1_5"/>
    <dbReference type="OMA" id="KICVEMG"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1610.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010318">
        <property type="entry name" value="DUF917"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024071">
        <property type="entry name" value="DUF917_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027479">
        <property type="entry name" value="DUF917_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06032">
        <property type="entry name" value="DUF917"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="BAF88725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="364" mass="39102" checksum="9C07F9E4FABB3393" modified="2007-12-04" version="1">MREITADEIEALAIGAWVLGTGGGGSPYLGLLNMRRLYAEGRRVQLMSPLDLADDDWVAVVSNMGAPLVGQERLADSRNTARAVRMQEEINGIKFRAVMSVEIGGGNGVQALMAAAELGIPVVDADCMGRAFPEAQMTSVAIGGLKPYPCTLYDPRGIEAVVTKVPSWKWMERASRKICVEMGSIASTSKAPRTGREVKDWGIHFTTTAAIRIGHVVMEANRRHEDPVAAILASEGGLKLFTGKVVDVARRTTEGFLRGSAVVEGLEEDRGSRLELSFQNEWIVAWRDGKAIATSPDLICVLDSVTGNGVGTETVRYGQRVSVIALPAPAVLTTPKGLEHVGPRAFGYDLDFHSLFQPSEGRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="62" xmlns="http://uniprot.org/uniprot">
    <accession>A8I9G6</accession>
    <name>A8I9G6_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MOSC domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_2787</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171311.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_2787"/>
    <dbReference type="EnsemblBacteria" id="BAF88785">
        <property type="protein sequence ID" value="BAF88785"/>
        <property type="gene ID" value="AZC_2787"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2787"/>
    <dbReference type="eggNOG" id="COG2258">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104911_0_0_5"/>
    <dbReference type="OMA" id="PPCAHVE"/>
    <dbReference type="OrthoDB" id="1877633at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="33"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF88785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="169" mass="19139" checksum="5EC94D4DE773765D" modified="2007-12-04" version="1">MLSLQPAIETPAPAFVGVVRHLHITARAFLPMRAMEEIHLVAGKGIEGDRYMIGREEGFYSDRPEEGRQVTLFEMETLDALLRDHKIELKPEDHRRNVTVEGVPLNHLVGRRFWLGETLLEATRLSVPCRHIEEITGKAIFDPLINRSGLNCRILEGGTVRIGDLVRNI</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2008-02-26" modified="2022-05-25" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>A8IAT8</accession>
    <name>RS12_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpsL</name>
        <name type="ordered locus">AZC_2559</name>
    </gene>
    <organism>
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="function">
        <text evidence="2">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF88557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171083.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A8IAT8"/>
    <dbReference type="SMR" id="A8IAT8"/>
    <dbReference type="STRING" id="438753.AZC_2559"/>
    <dbReference type="EnsemblBacteria" id="BAF88557">
        <property type="protein sequence ID" value="BAF88557"/>
        <property type="gene ID" value="AZC_2559"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_2559"/>
    <dbReference type="eggNOG" id="COG0048">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_104295_1_2_5"/>
    <dbReference type="OMA" id="SPALEKC"/>
    <dbReference type="OrthoDB" id="1707228at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword id="KW-0488">Methylation</keyword>
    <keyword id="KW-1185">Reference proteome</keyword>
    <keyword id="KW-0687">Ribonucleoprotein</keyword>
    <keyword id="KW-0689">Ribosomal protein</keyword>
    <keyword id="KW-0694">RNA-binding</keyword>
    <keyword id="KW-0699">rRNA-binding</keyword>
    <keyword id="KW-0820">tRNA-binding</keyword>
    <feature type="chain" id="PRO_1000072252" description="30S ribosomal protein S12">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
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        <location>
            <position position="89"/>
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    </feature>
    <evidence type="ECO:0000250" key="1"/>
    <evidence type="ECO:0000255" key="2">
        <source>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="1 2" key="4">
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Sato S."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="1 2" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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    </evidence>
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        <source>
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                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
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                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Akiba N."/>
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    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89191.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
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    </evidence>
    <sequence length="314" mass="32299" checksum="01E523D4ED19C43A" modified="2007-12-04" version="1">MMTVPSFVKNPALATVAAFLLLLALAHGLGFSHGATLVTRTLAYALAAVSLSFLIGQCGLVSFGHAAPFGIGAYAVLIAGEAGVREVLVVLPLAAAAAALFSAVTGAIALRTRGVYFIMITLAFAQMAFYVAASLSAYGGDDGMAIAGRSTFFGIRFLKADTSLALLAIALVGLALFLFQRLAASRFGLMLRAARANESKVEALGLAPYRHRLIALALAGAVAGLAGALIANQVEYVSPALMGWHVSGELIVMVVLGGIGHPVGAVIGAVVVTLLDESLGHLTEHWRLGLGLVIILVALLRDADLKSLLRGGSR</sequence>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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    <reference evidence="1 2" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        </source>
    </reference>
    <reference evidence="1 2" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
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                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
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    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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    <sequence length="122" mass="13808" checksum="4F3AE6E080459E12" modified="2007-12-04" version="1">MSDLFWLTDEQMQRIEPYFPLSHGVPRVDDRRIVSGIIFVIRNGLRWRDAPAAYGPPKTIYNRFIRWSRMGVFNRIFAGLVAEGGLPDQLMIDATHLKAHRTAASLLKKGLFPDVSGAPKEG</sequence>
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                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <sequence length="270" mass="28570" checksum="96C893113B153884" modified="2007-12-04" version="1">MRPILIMSAINGARRTKADHPALPLSPADIATESLRCAEAGASAIHLHVRDDEGRHSLDAGRYAEAIAEIRQRGARDLILQVTTEAVGLYGPAEQMAMVRTVRPEAFSVAVRELFSDPALACEATAFLADCAAGGMAVQYILYDGADVQRFDALAEAGQIPLANATQLFVLGRYGDGPPSTPAAILGFLSARRHMLDWSVCAFGPTESACCMAAALLGGDVRMGFENNLHLPDGRLAPDNAALVTHFVAAARALGLRPLELAEARARLGL</sequence>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="EMBL" id="BAF88924.1"/>
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    <sequence length="679" mass="72095" checksum="E3AB67000A828201" modified="2007-12-04" version="1">MRRNGAPVTAARQLSRVWSSMSSDPRALLGQASALHRAGRMDEAIEACRAAAKVAPGFLDAHRMLAFALLQVGRAKEAVRAAQKARDLAPRDPNSHLLVGAGLLGQGDAAKALAAFDEAAKLAPNLLEAHFQAGNALAALGRFPAAIERYNRALALDPRSVEALTNRATTYARLARHAEALADCERLIEMQPWSPLHLVAKASTLLEMGEPVPALAAAEAAMAAAPTFAEAFHVAGQAKAALMDISGAIDLMTQALALEPQPRPTVRVHLARLLRMEERFAEARRQCDLALADQPRLAPALAERAEVRRAEGDSAAAVRDADAAIAIARDFTPALLVRAAALADLGRPDEMRTAISRALRAAPRDPAALVAKSALDLARGEWAAGWLGYEQRENLLPPPFLPPAFPRWDGVAPVQDLVILAEQGIGDVLQFGRLLSLAADRGLPARFHARPALAPLAALLEPRIPVVTDISGIAADAPGTFWLPLASLAKLFAPDPAMWPVAPYLTAPAERVAKWAHLREGGGFRVGINWQGNPSRLIDVGRSAPLAAFAPLADLPGVRLISLQHGAAAEQIASVPFADRIETLGEGVDADGIFLDRAGILAHLDLVVTTDTSTAHLAGALGRPGLVALRAVPDWRWGESGEHSLFYPSLRLMRQETAGDWTGLFTRIAAAVKQTMATA</sequence>
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        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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    <sequence length="239" mass="26584" checksum="2B4BCDC63BE9BE47" modified="2007-12-04" version="1">MFADSSRFIMDLGMNNGDDTAYYLAKGFDVVAIEANPALVEAARTRFAKEIVAKRLTLVEAAVWATSGTVAFHVNEEDSRSSSVEEVWAKHHDAATHVVEVASLTLGDLFDRFGTPRYLKIDVRGADEIVLKQLRGQIIKPLYVSVEDCRSGYDFIAALDEAGYDGFKLVDQSRVTQVRDPKVNFRFTEGSSGPFGDALPGTWLDRKAFEKLYSTTVRDRAGNRIAPKNLWFDIHAAKL</sequence>
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                <person name="Miwa H."/>
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    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
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                <person name="Peng MH."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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                <person name="Aono T."/>
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                <person name="Suzuki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
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            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
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                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
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        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
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        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
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                <person name="Wiley G.B."/>
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                <person name="Binnewies T."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168606.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86073">
        <property type="protein sequence ID" value="BAF86073"/>
        <property type="gene ID" value="AZC_0075"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0075"/>
    <dbReference type="eggNOG" id="ENOG5033JZS">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_1352343_0_0_5"/>
    <dbReference type="OMA" id="GWPEGFG"/>
    <dbReference type="OrthoDB" id="1653025at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721013" evidence="1">
        <location>
            <begin position="28"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="202" mass="21104" checksum="74D6FA4D12986E0D" modified="2007-12-04" version="1">MSDRLSRRTALLLGAGALASVAAPATAQVIAPTANTVFVLPGVGQVTTLTYRAKVVSANPATRRVVLETPNGKRWAVKAPLIVGDLSLLRNGETIIVRLVPGLVTALGKARQGVPGEVINDVGLNDGLPGWPEGFGVRRVTITTILVNIDKVGGTISFEGPDGYVRTIKAADQKVLADLAQVNIGDLCQITYVEAMAFNALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-05-25" version="86" xmlns="http://uniprot.org/uniprot">
    <accession>A8IGM4</accession>
    <name>A8IGM4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fef-1</name>
        <name evidence="2" type="synonym">def</name>
        <name evidence="3" type="ordered locus">AZC_0108</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3 4" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168639.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0108"/>
    <dbReference type="EnsemblBacteria" id="BAF86106">
        <property type="protein sequence ID" value="BAF86106"/>
        <property type="gene ID" value="AZC_0108"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0108"/>
    <dbReference type="eggNOG" id="COG0242">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_061901_2_0_5"/>
    <dbReference type="OMA" id="NMHGEPV"/>
    <dbReference type="OrthoDB" id="1649129at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="BAF86106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="165" mass="18193" checksum="6444868A64FBEE44" modified="2007-12-04" version="1">MAVLDLVRFPDPRLRQPAEPVTVFDGALADRAQDLLDTMRAAPGIGITGPHAGLMIRLVALELPETAPAFYVNPRVLRASPEMGRHPEGSVSMPGVVEEVERPARVRVAFQGLDGTGHEVEADGLLSVCLQHEIDQLDGIFWIQRLSRLKRERVVKKYEKLLKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="70" xmlns="http://uniprot.org/uniprot">
    <accession>A8IIM3</accession>
    <name>A8IIM3_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2Fe-2S ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ordered locus">AZC_3424</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="5" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="4 5" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the adrenodoxin/putidaredoxin family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3424"/>
    <dbReference type="EnsemblBacteria" id="BAF89422">
        <property type="protein sequence ID" value="BAF89422"/>
        <property type="gene ID" value="AZC_3424"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3424"/>
    <dbReference type="eggNOG" id="COG0633">
        <property type="taxonomic scope" value="Bacteria"/>
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    <dbReference type="OMA" id="IPGNRIA"/>
    <dbReference type="Proteomes" id="UP000000270">
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    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="term" value="P:P450-containing electron transport chain"/>
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        <property type="project" value="InterPro"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin"/>
    </dbReference>
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        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="PTHR23426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ADRENODOXIN"/>
    </dbReference>
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        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF89422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="107" mass="11286" checksum="9CAE582469228DE4" modified="2007-12-04" version="1">MKEVSMTTVTISPGGEVLEAAEGMSLLEVLLKGDIKIPHKCDGKASCGSCHIFVQEGRKGLTKIAREENEKLDSIVGVGSKSRLACQAKVLGTENIKIELLGFGSGL</sequence>
</entry>
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    <accession>A8IIV0</accession>
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        <submittedName>
            <fullName evidence="7">Putative NAD-dependent formate dehydrogenase beta subunit protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ordered locus">AZC_3453</name>
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    <organism evidence="7 8">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
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    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="8" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="7 8" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF89451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012171976.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_3453"/>
    <dbReference type="EnsemblBacteria" id="BAF89451">
        <property type="protein sequence ID" value="BAF89451"/>
        <property type="gene ID" value="AZC_3453"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_3453"/>
    <dbReference type="eggNOG" id="COG1894">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_014881_3_0_5"/>
    <dbReference type="OMA" id="DRMLMEG"/>
    <dbReference type="OrthoDB" id="688908at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
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        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH_4Fe-4S" evidence="6">
        <location>
            <begin position="426"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="BAF89451.1"/>
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    </evidence>
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    <sequence length="519" mass="54714" checksum="83178F510607D1FC" modified="2007-12-04" version="1">MSVRIFVPNDATAIACGADKVARAIEAGLAARGIVANIVRNGSRGLFWLEPLVEVETPKGRVGYGPVKPSDVESLLAAGLVHGADHPLSVGLVEEIPFLKKQTRLTFARCGIIDPLSLEEYKAHGGYKGLAKAIEIGPSATVEQVFESGLRGRGGAGFPTGIKWRTVAAAPADQRYIVCNADEGDSGTFADRLIMEADPFCLIEGMTIAGLAVGATKGFVYCRSEYPLSLQVMEKAIAIARTAGLLGKNVAGSQYDFDLEMRMGAGAYVCGEETALLDSLEGKRGVVRAKPPLPAHKGLFGKPTVINNLISLATVPVILEKGGAFYRDFGMGRSRGTMPIQLAGNIKFGGIFETAFGIPLGELVYDIGGGTASGRPVRAVQAGGPLGAYLPVHQFDTPFDYEAFAAKDALIGHGGIVVFDDTVDMAHMARFAMEFCSHESCGKCTPCRIGSTRGVETLDKIIAGNRREANLAVLTDLCQTMKLGSLCALGGFTPYPVLSALTHFPEDFGATPKLPAAAE</sequence>
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                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
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                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
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                <person name="Holsters M."/>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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                <person name="Suzuki T."/>
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                <person name="Yamada M."/>
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                <person name="Ussery D.W."/>
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                <person name="Herder J.D."/>
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                <person name="Oyaizu H."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
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                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
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                <person name="Suzuki T."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Lee KB."/>
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    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="BAF86228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="1218" mass="132371" checksum="2592530295C97265" modified="2007-12-04" version="1">MIRMLPCRMSSSRLAGASGRRRALPTNGAGHALFLPKFGNRPRGTQNRARSGAALRFGRALFASCSWGLRRLSRFGTGRAEGNETGTVRLVRFGRPSFRPCSGHSGGSTGRVAFASRYGTELSPELPDPADRMDDVTKLAVLPPSIRARGVTAVLGPTNTGKTHLAIERMLGHESGLIGLPLRLLAREVYQRVVERVGAKNVALITGEEKIKPKNPRYWVATVEAMPRDVDVAFVAIDEVQLATDLDRGHVFTNRLLNRRGRFETMLLGSATMRPLIQKLMPGVTMVERPRLSTLMFAGEKKISRLPRRSAIVAFSAEEVYSIAEFIRRQRGGAAVVMGALSPRTRNAQVELYQNGDVDYLIATDAIGMGLNLDVDHVAFASDRKFDGWQFRRLNPMEMAQIAGRAGRAMRDGTFGTTGRCPPLDQELVERLEAHDFENARVLQWRNAVPDYRTIRTLTDSLALPPREEGLTRAPTGDDVQVLEIMSRDADVTARVTSPAVVERLWDVCQVPDYRKVSPGAHAELISTLFQYVGTGGRIPDDWFARQIALTDRAEGDIDTLSSRIAQVRTLTFVANRPDWLGDPEHWQGVTRGVEDKLSDALHERLAQRFVDRRTSMLMRRLRENTMLETEISKTGDVTVEGHVIGHLQGFQFAPDPTAGGEEAKALRAAAQKALAGEIETRANRLSQAVDEAFVLSHDGTVRWTGEPVAKLIPGDEVLKPRFKIIADEHLTGPARDQVEARLTLWVNAHIEKLLGSLNKLATAEDITGIARGIAFQIVESLGVLERTKVAEEMKTLDQTARATLRGYGVRFGAHHIYLPALLKPAPRTLAAQLYALKHGGLQQKGLDELPHLAASGRTSIPVDHEIQKGLYRAVGFRVCGERAVRVDILERLADLIRPALAWRPNSPGPKPPGAVDGRGFTVTVGMTSLAGCSGEDFASILKSLGYRMERRAAPPPEADTAAVTEAAPAPEAAEPLTPAPEGAIEADLLFEASEAPAPVEAHEDASHEDAPHEEHDALVEEVAEAAETEAVIAESADPTAAESAEEVGAVEAPAAGDATPAEAAEAVAGEANPEEPALIEVWRPGRPPGAPRREGAPGQKREGRGDNRGGERRDGRPGGQRRNGPPGDRPGQGHRPPRPEGEGEAAAQGERQGNRPPRSERFRVPQGDAPRGPRPERHGGGAPQQQDRRREKQADPDSPFAALAALKARLEAEKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="65" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJ49</accession>
    <name>A8IJ49_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168781.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0250"/>
    <dbReference type="EnsemblBacteria" id="BAF86248">
        <property type="protein sequence ID" value="BAF86248"/>
        <property type="gene ID" value="AZC_0250"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0250"/>
    <dbReference type="eggNOG" id="COG1801">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_046519_1_1_5"/>
    <dbReference type="OMA" id="CYFDNDV"/>
    <dbReference type="OrthoDB" id="1068600at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002763">
        <property type="entry name" value="DUF72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036520">
        <property type="entry name" value="UPF0759_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30348">
        <property type="entry name" value="PTHR30348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01904">
        <property type="entry name" value="DUF72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117396">
        <property type="entry name" value="SSF117396"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="315" mass="35439" checksum="09FEB7E66EF8F200" modified="2007-12-04" version="1">MAARHPPADVRIGVSGWTYAPWRGAFYPEGLGAKRELAYAAQVFRSLEVNGTFYGLQKPEVFARWAAETPDDFLFAVKGPRFITHMKRLKAVEAPLANFFASGVLKLGRKLGPVLWQLPASFPFNEARLDAFLSLLPRNMATASELARRHDARLEGRAAVGAETDGPLRHALEIRHDSYRTPAFTDLLRHHGVALVCADTVEWPLLMDATADFIYVRLHGSQELYRSAYPPEELDRWAARVRHWREGQAMTDGAFIDARSVPKRPRDVFVYFDNTDKLHAPDDARALMTRLGQTPGHPDVPVRRRRKIGAAEAHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="82" xmlns="http://uniprot.org/uniprot">
    <accession>A8IJP4</accession>
    <name>A8IJP4_AZOC5</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ordered locus">AZC_0337</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="16" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="15 16" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the transpeptidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="4"/>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0337"/>
    <dbReference type="CAZy" id="GT51">
        <property type="family name" value="Glycosyltransferase Family 51"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="BAF86335">
        <property type="protein sequence ID" value="BAF86335"/>
        <property type="gene ID" value="AZC_0337"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
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        <property type="project" value="UniProtKB-KW"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="14">
        <location>
            <begin position="176"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="13">
        <location>
            <begin position="435"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="728"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="33"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="736"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="BAF86335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="777" mass="83548" checksum="3DA01CF7BA770462" modified="2007-12-04" version="1">MTGLFMAGRGTGGQERREPSMRAASGSPEPSFDIRLDPEDRPGGGRKPARKADAAGGGRPARDQRARVEPSLDGDAAESEDMAAAPRRSKTEGSSRTSKGSTSSGGRGKAKSERRRKRGFFSLFGLIKWLFILGLWAAVGVGALVAYEASKLPPMQTLMVPKRPPTVMIQSFDGKPLATRGDMGGAAVPIKELPAYLPKAFVAIEDRRFYDHFGLDIWGLARAMAANAVSRRVRQGGSTLTQQLAKNLFLTQERTFSRKIQELVLALWLEKKFTKTEILDLYLNRVYFGNGAYGVEAAAQRYFNKSARNVTLSEAAMLAGLVNAPSRLAPTRNLKAAQDRANLVLAAMREQGFITEDMAKVALARPATLAKPSTPDSIGYVADWVMDQLDSYVGTLPGDVIVRTTIDPVLQQTAQASLTDALNKQGQKYGVGQGAVVSLDTDGAVKALVGGRSYEDSQYNRAVTARRQPGSSFKPFIYLTALEKGLTPETVREDGPIQLKGWKPENASHQYLGPVQLQQALAMSLNTVSVRLALEVGPKAVVATAHRLGITSTLDPNPSIALGTSEVSVLELASAYVPFANGGIGVIPYVIESVKGPDGKMLYSRSTSGPGRVIDPAYVGMMNHMLEQTIAVGTGRRAELPGWDAAGKTGTSQDYRDAWFVGYTARIVTAVWIGNDDSSPTKKASGANLPAEIWSRYMKVAHKDLPPTELPGAGRSYVASGTFGFGQQGGMLPPGQVPDEAPPAIVGNLPPQQPRPQQDEPMTLDRWFVDTFLGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2021-09-29" version="55" xmlns="http://uniprot.org/uniprot">
    <accession>A8IK46</accession>
    <name>A8IK46_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ordered locus">AZC_0399</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="3" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="18522759"/>
            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
            <authorList>
                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="19542345"/>
            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="20382809"/>
            <dbReference type="DOI" id="10.1128/AEM.00238-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2 3" key="6">
        <citation type="journal article" date="2011" name="Appl. Environ. Microbiol." volume="77" first="4371" last="4382">
            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="21571889"/>
            <dbReference type="DOI" id="10.1128/AEM.02327-10"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AP009384">
        <property type="protein sequence ID" value="BAF86397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_012168930.1">
        <property type="nucleotide sequence ID" value="NC_009937.1"/>
    </dbReference>
    <dbReference type="STRING" id="438753.AZC_0399"/>
    <dbReference type="EnsemblBacteria" id="BAF86397">
        <property type="protein sequence ID" value="BAF86397"/>
        <property type="gene ID" value="AZC_0399"/>
    </dbReference>
    <dbReference type="KEGG" id="azc:AZC_0399"/>
    <dbReference type="eggNOG" id="COG5451">
        <property type="taxonomic scope" value="Bacteria"/>
    </dbReference>
    <dbReference type="HOGENOM" id="CLU_118542_0_0_5"/>
    <dbReference type="OMA" id="NEGAKWR"/>
    <dbReference type="OrthoDB" id="1832893at2"/>
    <dbReference type="Proteomes" id="UP000000270">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012645">
        <property type="entry name" value="CHP02301"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09539">
        <property type="entry name" value="DUF2385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02301">
        <property type="entry name" value="TIGR02301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5002721129" evidence="1">
        <location>
            <begin position="28"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="BAF86397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000000270"/>
        </source>
    </evidence>
    <sequence length="135" mass="14511" checksum="705D3FDBF9BB3779" modified="2007-12-04" version="1">MRTFRSAALLLASAVWIAGLACGPAQAASSEGSTPPYEQDLLKIAELLGSLHYLRPLCGAPNEGQSWRTEMQTLIDAEQPSDPRKGKLIAAFNAGYNSYATVYRTCTPAAVEAVQRQMDQGAKLAHEIVVRYGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2007-12-04" modified="2022-08-03" version="78" xmlns="http://uniprot.org/uniprot">
    <accession>A8IKE7</accession>
    <name>A8IKE7_AZOC5</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ordered locus">AZC_3898</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)</name>
        <dbReference type="NCBI Taxonomy" id="438753"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Proteobacteria</taxon>
            <taxon>Alphaproteobacteria</taxon>
            <taxon>Hyphomicrobiales</taxon>
            <taxon>Xanthobacteraceae</taxon>
            <taxon>Azorhizobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" date="2007" name="Appl. Environ. Microbiol." volume="73" first="6650" last="6659">
            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
            </authorList>
            <dbReference type="PubMed" id="17720818"/>
            <dbReference type="DOI" id="10.1128/AEM.01514-07"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="2" key="2">
        <citation type="submission" date="2007-04" db="EMBL/GenBank/DDBJ databases">
            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
        </source>
    </reference>
    <reference evidence="1 2" key="3">
        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
                <person name="Aono T."/>
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                <person name="Lee KB."/>
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                <person name="Liu C.T."/>
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            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Backer P.D."/>
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                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
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            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
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            <title>Involvement of the azorhizobial chromosome partition gene (parA) in the onset of bacteroid differentiation during Sesbania rostrata stem nodule development.</title>
            <authorList>
                <person name="Liu CT."/>
                <person name="Lee KB."/>
                <person name="Wang YS."/>
                <person name="Peng MH."/>
                <person name="Lee KT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Oyaizu H."/>
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            <title>Rhizobial factors required for stem nodule maturation and maintenance in Sesbania rostrata-Azorhizobium caulinodans ORS571 symbiosis.</title>
            <authorList>
                <person name="Suzuki S."/>
                <person name="Aono T."/>
                <person name="Lee KB."/>
                <person name="Suzuki T."/>
                <person name="Liu CT."/>
                <person name="Miwa H."/>
                <person name="Wakao S."/>
                <person name="Iki T."/>
                <person name="Oyaizu H."/>
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            <title>Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium caulinodans ORS571.</title>
            <authorList>
                <person name="Lee K.B."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu C.T."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T."/>
                <person name="Ussery D."/>
                <person name="Vereecke D."/>
                <person name="Gevers D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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        <citation type="journal article" date="2008" name="BMC Genomics" volume="9" first="271" last="271">
            <title>The genome of the versatile nitrogen fixer Azorhizobium caulinodans ORS571.</title>
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                <person name="Lee KB."/>
                <person name="Backer P.D."/>
                <person name="Aono T."/>
                <person name="Liu CT."/>
                <person name="Suzuki S."/>
                <person name="Suzuki T."/>
                <person name="Kaneko T."/>
                <person name="Yamada M."/>
                <person name="Tabata S."/>
                <person name="Kupfer D.M."/>
                <person name="Najar F.Z."/>
                <person name="Wiley G.B."/>
                <person name="Roe B."/>
                <person name="Binnewies T.T."/>
                <person name="Ussery D.W."/>
                <person name="D'Haeze W."/>
                <person name="Herder J.D."/>
                <person name="Gevers D."/>
                <person name="Vereecke D."/>
                <person name="Holsters M."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1186/1471-2164-9-271"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="4">
        <citation type="journal article" date="2009" name="Appl. Environ. Microbiol." volume="75" first="5037" last="5046">
            <title>Comparative genome-wide transcriptional profiling of Azorhizobium caulinodans ORS571 grown under free-living and symbiotic conditions.</title>
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                <person name="Tsukada S."/>
                <person name="Aono T."/>
                <person name="Akiba N."/>
                <person name="Lee KB."/>
                <person name="Liu CT."/>
                <person name="Toyazaki H."/>
                <person name="Oyaizu H."/>
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            <dbReference type="DOI" id="10.1128/AEM.00398-09"/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    <reference evidence="5 6" key="5">
        <citation type="journal article" date="2010" name="Appl. Environ. Microbiol." volume="76" first="3475" last="3485">
            <title>phrR-like gene praR of Azorhizobium caulinodans ORS571 is essential for symbiosis with Sesbania rostrata and is involved in expression of reb genes.</title>
            <authorList>
                <person name="Akiba N."/>
                <person name="Aono T."/>
                <person name="Toyazaki H."/>
                <person name="Sato S."/>
                <person name="Oyaizu H."/>
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        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571</strain>
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